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Conserved domains on  [gi|1002341753|ref|NP_001307517|]
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acylphosphatase-2 isoform 4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acylphosphatase super family cl00551
Acylphosphatase;
2-73 4.34e-16

Acylphosphatase;


The actual alignment was detected with superfamily member pfam00708:

Pssm-ID: 444972  Cd Length: 85  Bit Score: 65.69  E-value: 4.34e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTISklEYSNFSI 73
Cdd:pfam00708 17 FVYRLAKELGLKGWVRNLPDGSVEIVVQGPEEDVDKFLEWLKS-GPPPARVDKVEVTEIDEPG--DFSGFEI 85
 
Name Accession Description Interval E-value
Acylphosphatase pfam00708
Acylphosphatase;
2-73 4.34e-16

Acylphosphatase;


Pssm-ID: 425830  Cd Length: 85  Bit Score: 65.69  E-value: 4.34e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTISklEYSNFSI 73
Cdd:pfam00708 17 FVYRLAKELGLKGWVRNLPDGSVEIVVQGPEEDVDKFLEWLKS-GPPPARVDKVEVTEIDEPG--DFSGFEI 85
AcyP COG1254
Acylphosphatase [Energy production and conversion];
2-74 4.35e-15

Acylphosphatase [Energy production and conversion];


Pssm-ID: 440866  Cd Length: 89  Bit Score: 63.25  E-value: 4.35e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTisKLEYSNFSIR 74
Cdd:COG1254   20 FTRRQARRLGLTGWVRNLPDGSVEVVAEGEEEAVEAFLEWLRK-GPPAARVEDVEVEEEEP--TGEFEGFEIR 89
PRK14424 PRK14424
acylphosphatase; Provisional
 3-67 9.69e-11

acylphosphatase; Provisional


Pssm-ID: 184674  Cd Length: 94  Bit Score: 52.53  E-value: 9.69e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTISKLE 67
Cdd:PRK14424  26 TVREAHALGLRGWVANLEDGTVEAMIQGPAAQIDRMLAWLRH-GPPAARVTEVTFEERRTEKRFE 89
 
Name Accession Description Interval E-value
Acylphosphatase pfam00708
Acylphosphatase;
2-73 4.34e-16

Acylphosphatase;


Pssm-ID: 425830  Cd Length: 85  Bit Score: 65.69  E-value: 4.34e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTISklEYSNFSI 73
Cdd:pfam00708 17 FVYRLAKELGLKGWVRNLPDGSVEIVVQGPEEDVDKFLEWLKS-GPPPARVDKVEVTEIDEPG--DFSGFEI 85
AcyP COG1254
Acylphosphatase [Energy production and conversion];
2-74 4.35e-15

Acylphosphatase [Energy production and conversion];


Pssm-ID: 440866  Cd Length: 89  Bit Score: 63.25  E-value: 4.35e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTisKLEYSNFSIR 74
Cdd:COG1254   20 FTRRQARRLGLTGWVRNLPDGSVEVVAEGEEEAVEAFLEWLRK-GPPAARVEDVEVEEEEP--TGEFEGFEIR 89
PRK14424 PRK14424
acylphosphatase; Provisional
 3-67 9.69e-11

acylphosphatase; Provisional


Pssm-ID: 184674  Cd Length: 94  Bit Score: 52.53  E-value: 9.69e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEKTISKLE 67
Cdd:PRK14424  26 TVREAHALGLRGWVANLEDGTVEAMIQGPAAQIDRMLAWLRH-GPPAARVTEVTFEERRTEKRFE 89
PRK14441 PRK14441
acylphosphatase; Provisional
 3-58 2.44e-10

acylphosphatase; Provisional


Pssm-ID: 172917  Cd Length: 93  Bit Score: 51.52  E-value: 2.44e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFS 58
Cdd:PRK14441  24 AADEARRLGVEGWVRNLPDGRVEAEAEGERAAVGALVRWCHA-GPPAARVDRVEVE 78
PRK14423 PRK14423
acylphosphatase; Provisional
 3-53 6.49e-10

acylphosphatase; Provisional


Pssm-ID: 237713  Cd Length: 92  Bit Score: 50.06  E-value: 6.49e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRID 53
Cdd:PRK14423  24 TRDTARELGVDGWVRNLDDGRVEAVFEGPRDAVEAMVEWCHE-GSPAAVVE 73
PRK14426 PRK14426
acylphosphatase; Provisional
 3-74 7.56e-09

acylphosphatase; Provisional


Pssm-ID: 184675  Cd Length: 92  Bit Score: 47.33  E-value: 7.56e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRtnFSNEKTISKLEYSNFSIR 74
Cdd:PRK14426  23 TQHEALKLGLTGYAKNLDDGSVEVVACGEEEQVEKLMEWLKEGGPRSARVDR--VLTEPHSPRGELTGFSIR 92
PRK14448 PRK14448
acylphosphatase; Provisional
 2-75 8.10e-09

acylphosphatase; Provisional


Pssm-ID: 172924  Cd Length: 90  Bit Score: 47.45  E-value: 8.10e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTnFSNEKTISKlEYSNFSIRY 75
Cdd:PRK14448  20 FTWQEATKIGIKGYVKNRPDGSVEVVAVGSDAQIAAFRDWLQH-GPPTAVVCNV-IEQDYQGSR-QFTHFSVRR 90
PRK14438 PRK14438
acylphosphatase; Provisional
 2-75 1.69e-08

acylphosphatase; Provisional


Pssm-ID: 172914  Cd Length: 91  Bit Score: 46.76  E-value: 1.69e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFsnEKTISKLEYSNFSIRY 75
Cdd:PRK14438  21 HTQQTAQRLNVSGWVKNLPNGSVQGCFEGEETDVAALIDWCHH-GPSRARVSGVIV--EREEFRGEFDDFDIRY 91
PRK14425 PRK14425
acylphosphatase; Provisional
 1-52 1.74e-08

acylphosphatase; Provisional


Pssm-ID: 172901  Cd Length: 94  Bit Score: 46.77  E-value: 1.74e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  1 MYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRI 52
Cdd:PRK14425  23 DWTRDEAERLGLTGWVRNESDGSVTALIAGPDSAISAMIERFRR-GPPGASV 73
PRK14436 PRK14436
acylphosphatase; Provisional
 6-54 1.86e-08

acylphosphatase; Provisional


Pssm-ID: 172912  Cd Length: 91  Bit Score: 46.50  E-value: 1.86e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 1002341753  6 EARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDR 54
Cdd:PRK14436  26 EARKLGVNGWVRNLPDGSVEAVLEGDEERVEALIGWAHQ-GPPLARVTR 73
PRK14420 PRK14420
acylphosphatase; Provisional
 2-75 4.79e-08

acylphosphatase; Provisional


Pssm-ID: 237710  Cd Length: 91  Bit Score: 45.57  E-value: 4.79e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEdkvNSMKSWLSKV--GSPSSRIdrTNFSNEKTISKLEYSNFSIRY 75
Cdd:PRK14420  20 FVQMEADKRKLTGWVKNRDDGTVEIEAEGPE---EALQLFLDAIekGSPFSKV--TDVHIEERDVLSGEKQFRIMY 90
PRK14447 PRK14447
acylphosphatase; Provisional
 4-73 5.75e-07

acylphosphatase; Provisional


Pssm-ID: 172923  Cd Length: 95  Bit Score: 43.00  E-value: 5.75e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002341753  4 EDEARKIGVVGWVKNTSKG-TVTGQVQGPEDKVNSMKSWlSKVGSPSSRIDRTNFSNEKTisKLEYSNFSI 73
Cdd:PRK14447  24 KEVANRNGVRGWVRNRSDGrTVEAVLEGPRDAVLKVIEW-ARVGPPGARVEDVEVKWEEY--KGEFQDFRI 91
PRK14442 PRK14442
acylphosphatase; Provisional
 3-44 2.56e-06

acylphosphatase; Provisional


Pssm-ID: 172918  Cd Length: 91  Bit Score: 41.02  E-value: 2.56e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSK 44
Cdd:PRK14442  23 TREEADRLELDGWVRNLDDGRVEVVWEGEEDRAKALERWLGR 64
PRK14444 PRK14444
acylphosphatase; Provisional
 2-61 5.52e-06

acylphosphatase; Provisional


Pssm-ID: 172920  Cd Length: 92  Bit Score: 40.25  E-value: 5.52e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFSNEK 61
Cdd:PRK14444  22 YTRDRAREAGVKGWVRNLSDGRVEAVFEGSRPAVQKMISWCYS-GPSHARVERVEVHWEE 80
HypF COG0068
Hydrogenase maturation factor HypF (carbamoyltransferase) [Posttranslational modification, ...
 7-74 1.34e-05

Hydrogenase maturation factor HypF (carbamoyltransferase) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 439838 [Multi-domain]  Cd Length: 757  Bit Score: 40.86  E-value: 1.34e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002341753   7 ARKIGVVGWVKNTSKGtVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRTNFsneKTISKLEYSNFSIR 74
Cdd:COG0068    25 AKELGLKGWVRNDGGG-VEIEVEGEEEALEAFLEALRAEAPPLARIDSIEV---EELPPEGFDGFRIL 88
PRK14427 PRK14427
acylphosphatase; Provisional
 2-75 1.65e-05

acylphosphatase; Provisional


Pssm-ID: 172903  Cd Length: 94  Bit Score: 39.09  E-value: 1.65e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPsSRIDRTNFSNEKTISklEYSNFSIRY 75
Cdd:PRK14427  24 WTMRKAEELGLTGTVRNLDDGSVALVAEGTGEQVEKLLDWLNSDRAP-GRVERVDHTVSEATG--EFREFRARD 94
PRK14428 PRK14428
acylphosphatase; Provisional
 2-43 5.34e-05

acylphosphatase; Provisional


Pssm-ID: 172904  Cd Length: 97  Bit Score: 37.80  E-value: 5.34e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLS 43
Cdd:PRK14428  26 FTVTQARRLGVQGWVRNCRDGSVELEAQGSSDAVQALVEQLA 67
PRK14421 PRK14421
acylphosphatase; Provisional
 2-53 1.06e-04

acylphosphatase; Provisional


Pssm-ID: 237711 [Multi-domain]  Cd Length: 99  Bit Score: 37.09  E-value: 1.06e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1002341753  2 YTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSwLSKVGSPSSRID 53
Cdd:PRK14421  22 WVARTAEALGLEGWVRNRRDGSVEALFAGPADAVAEMIA-RCRRGPSAARVD 72
PRK14430 PRK14430
acylphosphatase; Provisional
 5-54 1.36e-04

acylphosphatase; Provisional


Pssm-ID: 172906  Cd Length: 92  Bit Score: 36.82  E-value: 1.36e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 1002341753  5 DEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLsKVGSPSSRIDR 54
Cdd:PRK14430  25 DAADDLGLGGWVRNRADGTVEVMASGTVRQLEALRAWM-EAGPPAAQVTK 73
PRK14445 PRK14445
acylphosphatase; Provisional
 1-38 4.12e-04

acylphosphatase; Provisional


Pssm-ID: 172921  Cd Length: 91  Bit Score: 35.21  E-value: 4.12e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 1002341753  1 MYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSM 38
Cdd:PRK14445  21 MFIDRAASELNLSGWVRNLPDGTVEIEAQGSSGMIDEL 58
PRK14451 PRK14451
acylphosphatase; Provisional
 3-73 5.78e-04

acylphosphatase; Provisional


Pssm-ID: 237715  Cd Length: 89  Bit Score: 34.90  E-value: 5.78e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002341753  3 TEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFsnEKTISKlEYSNFSI 73
Cdd:PRK14451  22 AKKLAEQLMISGWARNLADGRVEVFACGKEDKLEEFYTWLQK-GPLNARVDVCTR--ENLPWQ-DYISFDV 88
PRK14437 PRK14437
acylphosphatase; Provisional
 6-74 2.76e-03

acylphosphatase; Provisional


Pssm-ID: 172913  Cd Length: 109  Bit Score: 33.55  E-value: 2.76e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002341753   6 EARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKvGSPSSRIDRTNFsneKTISKLEYSNFSIR 74
Cdd:PRK14437   45 KAEELQLTGWVKNLSHGDVELVACGERDSIMILTEWLWE-GPPQAAVSNVNW---EEIVVEDYSDFRVR 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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