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Conserved domains on  [gi|1012139188|ref|NP_001308607|]
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leucine-rich repeat-containing protein 28 isoform 5 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-176 4.95e-24

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.01  E-value: 4.95e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  17 QKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDI 96
Cdd:COG4886   110 SNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDL 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  97 STNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPlDLGRSRELQYVYVDNNiHLKGLPS 176
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNN-QLTDLPP 267
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-176 4.95e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.01  E-value: 4.95e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  17 QKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDI 96
Cdd:COG4886   110 SNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDL 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  97 STNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPlDLGRSRELQYVYVDNNiHLKGLPS 176
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNN-QLTDLPP 267
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
10-258 4.73e-13

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 68.57  E-value: 4.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  10 NFPENLAQklpNLVELYLHSNNIVVVPEAIGSLVklQCLDLSDNALeIVCPEigrlralrhlrlannqlqFLPpevgdlK 89
Cdd:PRK15370  213 SLPENLQG---NIKTLYANSNQLTSIPATLPDTI--QEMELSINRI-TELPE------------------RLP------S 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  90 ELQTLDISTNRLLTLPERLHMclSLQYLTVDRNRLWYVPRHlcqLPS-LNELSMAGNRLAFLPLDLgrSRELQYVYVDNN 168
Cdd:PRK15370  263 ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAH---LPSgITHLNVQSNSLTALPETL--PPGLKTLEAGEN 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188 169 IhLKGLPSYLynkvigcsgcgaPiqvSEVKLLSFSSGQRTVF---LPAEVKAIGTEHDHVLPLQE---LAMRGLYHTYHS 242
Cdd:PRK15370  336 A-LTSLPASL------------P---PELQVLDVSKNQITVLpetLPPTITTLDVSRNALTNLPEnlpAALQIMQASRNN 399

                         250
                  ....*....|....*.
gi 1012139188 243 LLKGRQLLVLWLTAAP 258
Cdd:PRK15370  400 LVRLPESLPHFRGEGP 415
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 13-147 6.53e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.77  E-value: 6.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  13 ENLaQKLPNLVELYLHSNNIVVVpEAIGSLVKLQCLDLSDNALEIVcpeigrlralrhlrlanNQLQflppevgDLKELQ 92
Cdd:cd21340    40 ENL-EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-----------------EGLE-------NLTNLE 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012139188  93 TLDISTNRL-----LTLPERLHMCL--SLQYLTVDRNRLWYVpRHLCQLPSLNELSMAGNRL 147
Cdd:cd21340    94 ELHIENQRLppgekLTFDPRSLAALsnSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQI 154
LRR_8 pfam13855
Leucine rich repeat;
20-101 1.77e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  20 PNLVELYLHSNNIVVV-PEAIGSLVKLQCLDLSdnaleivcpeigrlralrhlrlaNNQLQFLPPEV-GDLKELQTLDIS 97
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLS-----------------------NNLLTTLSPGAfSGLPSLRYLDLS 57


                  ....
gi 1012139188  98 TNRL 101
Cdd:pfam13855  58 GNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-176 4.95e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.01  E-value: 4.95e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  17 QKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDI 96
Cdd:COG4886   110 SNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDL 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  97 STNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPlDLGRSRELQYVYVDNNiHLKGLPS 176
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNN-QLTDLPP 267
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
10-258 4.73e-13

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 68.57  E-value: 4.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  10 NFPENLAQklpNLVELYLHSNNIVVVPEAIGSLVklQCLDLSDNALeIVCPEigrlralrhlrlannqlqFLPpevgdlK 89
Cdd:PRK15370  213 SLPENLQG---NIKTLYANSNQLTSIPATLPDTI--QEMELSINRI-TELPE------------------RLP------S 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  90 ELQTLDISTNRLLTLPERLHMclSLQYLTVDRNRLWYVPRHlcqLPS-LNELSMAGNRLAFLPLDLgrSRELQYVYVDNN 168
Cdd:PRK15370  263 ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAH---LPSgITHLNVQSNSLTALPETL--PPGLKTLEAGEN 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188 169 IhLKGLPSYLynkvigcsgcgaPiqvSEVKLLSFSSGQRTVF---LPAEVKAIGTEHDHVLPLQE---LAMRGLYHTYHS 242
Cdd:PRK15370  336 A-LTSLPASL------------P---PELQVLDVSKNQITVLpetLPPTITTLDVSRNALTNLPEnlpAALQIMQASRNN 399

                         250
                  ....*....|....*.
gi 1012139188 243 LLKGRQLLVLWLTAAP 258
Cdd:PRK15370  400 LVRLPESLPHFRGEGP 415
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
10-124 2.03e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.41  E-value: 2.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  10 NFPENLAQkLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPpEVGDLK 89
Cdd:COG4886   173 DLPEELGN-LTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLT 250

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1012139188  90 ELQTLDISTNRLLTLPERLHMClSLQYLTVDRNRL 124
Cdd:COG4886   251 NLEELDLSNNQLTDLPPLANLT-NLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
10-104 1.75e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 57.64  E-value: 1.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  10 NFPENLAQkLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVcPEIGRLRALRHLRLANNQLQFLPPEvGDLK 89
Cdd:COG4886   196 DLPEPLGN-LTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLPPL-ANLT 272

                          90
                  ....*....|....*
gi 1012139188  90 ELQTLDISTNRLLTL 104
Cdd:COG4886   273 NLKTLDLSNNQLTDL 287
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
3-154 4.01e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.93  E-value: 4.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188   3 YIQSWRPNFpENLAQKLPN-LVELYLHSNNIVVVPEAIGslVKLQCLDLSDNALEIVcPEIgrlralrhlrlannqlqfL 81
Cdd:PRK15370  287 YLSVYDNSI-RTLPAHLPSgITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSL-PAS------------------L 344

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1012139188  82 PPEvgdlkeLQTLDISTNRLLTLPERLHMclSLQYLTVDRNRLWYVPRHlcqLP-SLNELSMAGNRLAFLPLDL 154
Cdd:PRK15370  345 PPE------LQVLDVSKNQITVLPETLPP--TITTLDVSRNALTNLPEN---LPaALQIMQASRNNLVRLPESL 407
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
29-180 7.18e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 52.63  E-value: 7.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  29 SNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLperl 108
Cdd:COG4886    36 ALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSN---- 111

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012139188 109 hmCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNNiHLKGLPSYLYN 180
Cdd:COG4886   112 --LTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN-QLTDLPEELGN 180
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 25-180 7.73e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.85  E-value: 7.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  25 LYLH-SNNIVVVPEAIGSLVKLQCLDLSDNALEIVCP-EIGRLRALRHLRLANNQLQ-FLPPEVGDLKELQTLDISTNRL 101
Cdd:PLN00113  121 RYLNlSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPnDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQL 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188 102 L-TLPERLHMCLSLQYLTVDRNRL-WYVPRHLCQLPSLNELSMAGNRLAF-LPLDLGRSRELQYVYVDNNIHLKGLPSYL 178
Cdd:PLN00113  201 VgQIPRELGQMKSLKWIYLGYNNLsGEIPYEIGGLTSLNHLDLVYNNLTGpIPSSLGNLKNLQYLFLYQNKLSGPIPPSI 280


                  ..
gi 1012139188 179 YN 180
Cdd:PLN00113  281 FS 282
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 18-176 1.62e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.99  E-value: 1.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  18 KLPNLVELYLHSNNIV-VVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQ-FLPPEVGDLKELQTLD 95
Cdd:PLN00113  426 KLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSELMQLK 505

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  96 ISTNRLL-TLPERLHMCLSLQYLTVDRNRL-WYVPRHLCQLPSLNELSMAGNRLAF-LPLDLGRSRELQYVYVDNNiHLK 172
Cdd:PLN00113  506 LSENKLSgEIPDELSSCKKLVSLDLSHNQLsGQIPASFSEMPVLSQLDLSQNQLSGeIPKNLGNVESLVQVNISHN-HLH 584


                  ....*
gi 1012139188 173 G-LPS 176
Cdd:PLN00113  585 GsLPS 589
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 19-176 1.94e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.61  E-value: 1.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  19 LPNLVELYLHSNNIV-VVPEAIGSLVKLQCLDLSDNALEIVCPE--IGRLRALRHLRLANNQLQFLPPEVGDLKELQTLD 95
Cdd:PLN00113  259 LKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGEIPElvIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQ 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  96 ISTNRLL-TLPERLHMCLSLQYLTVDRNRL-WYVPRHLCQLPSLNELSMAGNRL-AFLPLDLGRSRELQYVYVDNNiHLK 172
Cdd:PLN00113  339 LWSNKFSgEIPKNLGKHNNLTVLDLSTNNLtGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDN-SFS 417


                  ....*
gi 1012139188 173 G-LPS 176
Cdd:PLN00113  418 GeLPS 422
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
20-175 3.49e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 44.77  E-value: 3.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  20 PNLVELYLHSNNIVVVPEAIGSLVKL-----------------QCLDLSDNALEIVcPEIgrLRALRHLRLANNQLQFLP 82
Cdd:PRK15387  262 PGLLELSIFSNPLTHLPALPSGLCKLwifgnqltslpvlppglQELSVSDNQLASL-PAL--PSELCKLWAYNNQLTSLP 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  83 PEVGDLKELQTLDISTNRLLTLPERLHmclslqyltvdrnRLWYVPRHLCQLPS----LNELSMAGNRLAFLPLdlgRSR 158
Cdd:PRK15387  339 TLPSGLQELSVSDNQLASLPTLPSELY-------------KLWAYNNRLTSLPAlpsgLKELIVSGNRLTSLPV---LPS 402

                         170
                  ....*....|....*..
gi 1012139188 159 ELQYVYVDNNiHLKGLP 175
Cdd:PRK15387  403 ELKELMVSGN-RLTSLP 418
PLN03150 PLN03150
hypothetical protein; Provisional
 80-155 4.75e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.34  E-value: 4.75e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1012139188  80 FLPPEVGDLKELQTLDISTNRLL-TLPERLHMCLSLQYLTVDRNRL-WYVPRHLCQLPSLNELSMAGNRLA-FLPLDLG 155
Cdd:PLN03150  433 FIPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFnGSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 13-147 6.53e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.77  E-value: 6.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  13 ENLaQKLPNLVELYLHSNNIVVVpEAIGSLVKLQCLDLSDNALEIVcpeigrlralrhlrlanNQLQflppevgDLKELQ 92
Cdd:cd21340    40 ENL-EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-----------------EGLE-------NLTNLE 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012139188  93 TLDISTNRL-----LTLPERLHMCL--SLQYLTVDRNRLWYVpRHLCQLPSLNELSMAGNRL 147
Cdd:cd21340    94 ELHIENQRLppgekLTFDPRSLAALsnSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQI 154
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
78-176 8.54e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 40.53  E-value: 8.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  78 LQFLPPEvgdlkeLQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQL--------------PSLNELSMA 143
Cdd:PRK15387  237 LPALPPE------LRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLwifgnqltslpvlpPGLQELSVS 310

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1012139188 144 GNRLAFLPldlGRSRELQYVYVDNNiHLKGLPS 176
Cdd:PRK15387  311 DNQLASLP---ALPSELCKLWAYNN-QLTSLPT 339
PLN03150 PLN03150
hypothetical protein; Provisional
 34-124 1.64e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 39.41  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  34 VVPEAIGSLVKLQCLDLSDNALEIVcpeigrlralrhlrlannqlqfLPPEVGDLKELQTLDISTNRLL-TLPERLHMCL 112
Cdd:PLN03150  433 FIPNDISKLRHLQSINLSGNSIRGN----------------------IPPSLGSITSLEVLDLSYNSFNgSIPESLGQLT 490

                          90
                  ....*....|..
gi 1012139188 113 SLQYLTVDRNRL 124
Cdd:PLN03150  491 SLRILNLNGNSL 502
LRR_8 pfam13855
Leucine rich repeat;
20-101 1.77e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  20 PNLVELYLHSNNIVVV-PEAIGSLVKLQCLDLSdnaleivcpeigrlralrhlrlaNNQLQFLPPEV-GDLKELQTLDIS 97
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLS-----------------------NNLLTTLSPGAfSGLPSLRYLDLS 57


                  ....
gi 1012139188  98 TNRL 101
Cdd:pfam13855  58 GNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 18-160 3.25e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 38.68  E-value: 3.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  18 KLPNLVELYLHSNNIV-VVPEAIGSLVKLQCLDLsdnaleivcpeigrlralrhlrLANNQLQFLPPEVGDLKELQ---- 92
Cdd:PLN00113  210 QMKSLKWIYLGYNNLSgEIPYEIGGLTSLNHLDL----------------------VYNNLTGPIPSSLGNLKNLQylfl 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  93 --------------------TLDISTNRLL-TLPERLHMCLSLQYLTVDRNRLW-YVPRHLCQLPSLNELSMAGNRLAF- 149
Cdd:PLN00113  268 yqnklsgpippsifslqkliSLDLSDNSLSgEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSGe 347

                         170
                  ....*....|.
gi 1012139188 150 LPLDLGRSREL 160
Cdd:PLN00113  348 IPKNLGKHNNL 358
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
18-106 5.12e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 37.99  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012139188  18 KLPNLVELYLHSNNIVVVPEaIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDIS 97
Cdd:COG4886   248 NLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLL 326


                  ....*....
gi 1012139188  98 TNRLLTLPE 106
Cdd:COG4886   327 LLLLKGLLV 335
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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