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Conserved domains on  [gi|1012282653|ref|NP_001308658|]
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exocyst complex component 6B isoform 1 [Homo sapiens]

Protein Classification

SEC15 family protein( domain architecture ID 10513678)

SEC15 family protein similar to human exocyst complex component 6A/B, which are components of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
465-771 2.09e-122

Exocyst complex subunit Sec15-like;


:

Pssm-ID: 461169  Cd Length: 308  Bit Score: 370.71  E-value: 2.09e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 465 YKKVVGQFPFQDIELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 540
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 541 SLQNVIKrKNIGLTELVQIIINTTHLEKSCKYLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 620
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 621 FLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFA-VFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQF 699
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPESVKTLVYFRALDHIAESLLDLLLSPDVKRINENAVSNF 238

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012282653 700 NLDVRECEQFARSGPVPGFqEDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPNCKYLRVNPVTALTLLEKI 771
Cdd:pfam04091 239 DLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLEKL 308
 
Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
465-771 2.09e-122

Exocyst complex subunit Sec15-like;


Pssm-ID: 461169  Cd Length: 308  Bit Score: 370.71  E-value: 2.09e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 465 YKKVVGQFPFQDIELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 540
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 541 SLQNVIKrKNIGLTELVQIIINTTHLEKSCKYLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 620
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 621 FLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFA-VFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQF 699
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPESVKTLVYFRALDHIAESLLDLLLSPDVKRINENAVSNF 238

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012282653 700 NLDVRECEQFARSGPVPGFqEDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPNCKYLRVNPVTALTLLEKI 771
Cdd:pfam04091 239 DLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLEKL 308
 
Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
465-771 2.09e-122

Exocyst complex subunit Sec15-like;


Pssm-ID: 461169  Cd Length: 308  Bit Score: 370.71  E-value: 2.09e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 465 YKKVVGQFPFQDIELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 540
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 541 SLQNVIKrKNIGLTELVQIIINTTHLEKSCKYLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 620
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012282653 621 FLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFA-VFTHLPGKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQF 699
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPESVKTLVYFRALDHIAESLLDLLLSPDVKRINENAVSNF 238

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1012282653 700 NLDVRECEQFARSGPVPGFqEDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPNCKYLRVNPVTALTLLEKI 771
Cdd:pfam04091 239 DLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLEKL 308
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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