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Conserved domains on  [gi|1677501140|ref|NP_001308836|]
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inactive dipeptidyl peptidase 10 isoform e [Homo sapiens]

Protein Classification

S9 family peptidase( domain architecture ID 12012129)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues

CATH:  3.40.50.1820|2.140.10.30
EC:  3.4.-.-
Gene Ontology:  GO:0008236|GO:0006508
MEROPS:  S9
PubMed:  19508187|12369917|35631755
SCOP:  3000102

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 133-486 3.12e-133

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 399.38  E-value: 3.12e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 133 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 212
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 213 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 291
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 292 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGAC-SKNEE--------- 361
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTvVILEEtsdgwvelh 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 362 ---PVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQ 438
Cdd:pfam00930 236 qdpHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1677501140 439 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 486
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
567-769 2.59e-49

Prolyl oligopeptidase family;


:

Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 2.59e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 567 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 645
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 646 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 718
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1677501140 719 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 769
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 133-486 3.12e-133

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 399.38  E-value: 3.12e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 133 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 212
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 213 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 291
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 292 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGAC-SKNEE--------- 361
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTvVILEEtsdgwvelh 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 362 ---PVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQ 438
Cdd:pfam00930 236 qdpHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1677501140 439 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 486
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
567-769 2.59e-49

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 2.59e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 567 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 645
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 646 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 718
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1677501140 719 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 769
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
582-769 3.62e-41

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.55  E-value: 3.62e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 582 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 661
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 662 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNVHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 738
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1677501140 739 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 769
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
PLN02442 PLN02442
S-formylglutathione hydrolase
 618-746 3.01e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 43.61  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 618 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 687
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 688 TYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 746
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 133-486 3.12e-133

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 399.38  E-value: 3.12e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 133 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 212
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 213 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 291
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 292 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGAC-SKNEE--------- 361
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTvVILEEtsdgwvelh 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 362 ---PVFSRDGSKFFMTVPvKQGgrgeFHHVAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQ 438
Cdd:pfam00930 236 qdpHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1677501140 439 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 486
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
567-769 2.59e-49

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 172.80  E-value: 2.59e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 567 FHIDWD-SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAS 645
Cdd:pfam00326   1 PSFSWNaQLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 646 MILKSDEKLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNVHGLKEEN-ILIIHGTADTKVH 718
Cdd:pfam00326  80 AALNQRPDLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1677501140 719 FQHSAELIKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 769
Cdd:pfam00326 160 PWQSLKLVAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
582-769 3.62e-41

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.55  E-value: 3.62e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 582 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 661
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 662 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNVHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 738
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1677501140 739 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 769
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 582-768 9.20e-09

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 56.85  E-value: 9.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 582 IVARFDGRGSGF-QGLkilqeiHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKlFKCGSV 660
Cdd:COG1073    66 NVLAFDYRGYGEsEGE------PREEGSPERRDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPR-VKAVIL 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 661 VAPITDLK-----LYASAFSERYLGMPSKEESTY-----QAASVLHNVHGLKeENILIIHGTADTKVHFQHSAELIKhli 730
Cdd:COG1073   139 DSPFTSLEdlaaqRAKEARGAYLPGVPYLPNVRLasllnDEFDPLAKIEKIS-RPLLFIHGEKDEAVPFYMSEDLYE--- 214

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1677501140 731 KAGVNYTMQVYPDEGHNVSEKSKYHLY-STILKFFSDCL 768
Cdd:COG1073   215 AAAEPKELLIVPGAGHVDLYDRPEEEYfDKLAEFFKKNL 253
COG4099 COG4099
Predicted peptidase [General function prediction only];
617-748 5.80e-07

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 51.51  E-value: 5.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 617 AVKFLLKLPYIDSKRLSIFGKGYGGYIA-SMILKSDEkLFKCGSVVAPITDLklyasAFSERYLGMPskeestyqaasvl 695
Cdd:COG4099   112 LLDDLIAEYRIDPDRIYLTGLSMGGYGTwDLAARYPD-LFAAAVPICGGGDP-----ANAANLKKVP------------- 172

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1677501140 696 hnvhglkeenILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNV 748
Cdd:COG4099   173 ----------VWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHNS 215
YpfH COG0400
Predicted esterase [General function prediction only];
627-750 5.37e-05

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 44.90  E-value: 5.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 627 IDSKRLSIFGKGYGGYIASMILKSDEKLFKCgsVVApitdlklyasaFSerylGMPSKEESTYQAASVLHNVHglkeenI 706
Cdd:COG0400    86 IDPERIVLAGFSQGAAMALSLALRRPELLAG--VVA-----------LS----GYLPGEEALPAPEAALAGTP------V 142

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1677501140 707 LIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDeGHNVSE 750
Cdd:COG0400   143 FLAHGTQDPVIPVERAREAAEALEAAGADVTYREYPG-GHEISP 185
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
611-746 2.67e-04

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 43.03  E-value: 2.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 611 VKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAsMILKSDEKLFKCgsVVApitdlklyasafserYLGMPSKEESTYQ 690
Cdd:COG0412    90 AADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLA-LLAAARGPDLAA--AVS---------------FYGGLPADDLLDL 151

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1677501140 691 AASVLHNVhglkeeniLIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 746
Cdd:COG0412   152 AARIKAPV--------LLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGH 199
PLN02442 PLN02442
S-formylglutathione hydrolase
 618-746 3.01e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 43.61  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 618 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 687
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 688 TYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 746
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
583-766 2.31e-03

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 40.37  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 583 VARFDGRGSGfqglkilqEIHRRLGSVE-----VKDQITAVKFLLKLPyidSKRLSIFGKGYGGYIASMILKSDEKLFKc 657
Cdd:COG2267    58 VLAFDLRGHG--------RSDGPRGHVDsfddyVDDLRAALDALRARP---GLPVVLLGHSMGGLIALLYAARYPDRVA- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677501140 658 gSVVapitdlkLYASAFSERYLGMPSkeESTYQAASVLHNVHGLKEEnILIIHGTADTKVHFQHSAELIKHLIKAGvnyT 737
Cdd:COG2267   126 -GLV-------LLAPAYRADPLLGPS--ARWLRALRLAEALARIDVP-VLVLHGGADRVVPPEAARRLAARLSPDV---E 191

                         170       180       190
                  ....*....|....*....|....*....|
gi 1677501140 738 MQVYPDEGHNV-SEKSKYHLYSTILKFFSD 766
Cdd:COG2267   192 LVLLPGARHELlNEPAREEVLAAILAWLER 221
PRK11460 PRK11460
putative hydrolase; Provisional
 673-746 9.61e-03

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 38.48  E-value: 9.61e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1677501140 673 AFSERYLGMPSKEestyQAASVLHnvhglkeenilIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 746
Cdd:PRK11460  133 AFSGRYASLPETA----PTATTIH-----------LIHGGEDPVIDVAHAVAAQEALISLGGDVTLDIVEDLGH 191
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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