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Conserved domains on  [gi|1041817999|ref|NP_001316055|]
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dnaJ homolog subfamily C member 13 isoform 1 [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 18340985)

J domain-containing protein similar to the N-terminal conserved domain (called J domain) of DnaJ-like proteins, which is involved in regulating the ATPase activity of heat shock protein 70 (Hsp70) by ATP hydrolysis

Gene Ontology:  GO:0006457
PubMed:  9585179|23894646|15170475|9644977

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-836 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


:

Pssm-ID: 466078  Cd Length: 819  Bit Score: 1490.18  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   12 CFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQG-TEFNLTFRKGsgKKSETLKFSTEHR 90
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGpNEFIITTRKK--GKSDTMRFSSEYR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   91 TELLTEALRFRTDFSEGKI--TGRRYNCYKHHWSDSRKPVILEVTPGGFDQINPATNRVLCSYDYRNIEGFVDLSDYQGG 168
Cdd:pfam19432   79 AEILTDALRYRAKFADEYKdkLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGIILVSDYPGG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  169 FCILYGGFSRLHLFASEQREEIIKSAIDHAGNYIGISLRIRKEPLEFEQYLNLRFGKYSTDESITSLAEFVVQKISPRHS 248
Cdd:pfam19432  159 FVILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHP 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  249 EPVKRVLALTETCLVERDPATYNIATLKPLGEVFALVCDSENPQLFTIEFIKGQVRKYSSTERDSLLASLLDGVRASGNR 328
Cdd:pfam19432  239 DPVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNR 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  329 DVCVKMTPTHKGQRWGLLSMPVDEEVESLHLRFLATPPNG-NFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNA 407
Cdd:pfam19432  319 DVHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLISPPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVSA 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  408 ITALLSQEGDVVA-SNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGVKVVKALKRSNNGIIHAAVDMLCALMCPMH 486
Cdd:pfam19432  399 LEALLEEEGDQDFiSPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQPMH 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  487 DDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTL 566
Cdd:pfam19432  479 DNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRGRSL 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  567 FKLFQHPSMAIIKGAGLVMKAIIEEGDKEIATKMQELALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNA 646
Cdd:pfam19432  559 FKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWITGNP 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  647 TATNLLKRILPPGLLAYLESSDLVPEKDADRMHVRDNVKIAMDQYGKFNKVPEwqrlagkaakevEKFAKEKVDLVLMHW 726
Cdd:pfam19432  639 DAMDLLKRILPAGLLDYLDSTEEPPEDEEDLLNTRDNLKMATDHSEQKSGLKE------------QKTVEKHVEGLLQHW 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  727 RDRMGIAQKEDKnnmniNQKPVVLRKRRQRIKIEANWDLFYYRFGQDHARSNLIWNFKTREELKDTLESEMRAFNIDREL 806
Cdd:pfam19432  707 RLRIGLEFKKKF-----QQRPVVLRKRRQRVKSEANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKEL 781

                          810       820       830
                   ....*....|....*....|....*....|
gi 1041817999  807 GSANVISWNHHEFEVKYECLAEEIKIGDYY 836
Cdd:pfam19432  782 AGDKVISWNHTEFEVRYPSLADEIKIGDYY 811
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1306-1359 5.73e-16

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 74.05  E-value: 5.73e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFLC 1359
Cdd:pfam00226    1 DYYEILGVSPDA---SDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 981-1031 1.94e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


:

Pssm-ID: 464112  Cd Length: 50  Bit Score: 72.19  E-value: 1.94e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1041817999  981 WYFGNaDKERSGPYGFHEMQELWTKGMLNAKTRCWAQGMDGWRPLQSIPQL 1031
Cdd:pfam14237    1 WYYAV-NGQQQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
 
Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-836 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


Pssm-ID: 466078  Cd Length: 819  Bit Score: 1490.18  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   12 CFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQG-TEFNLTFRKGsgKKSETLKFSTEHR 90
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGpNEFIITTRKK--GKSDTMRFSSEYR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   91 TELLTEALRFRTDFSEGKI--TGRRYNCYKHHWSDSRKPVILEVTPGGFDQINPATNRVLCSYDYRNIEGFVDLSDYQGG 168
Cdd:pfam19432   79 AEILTDALRYRAKFADEYKdkLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGIILVSDYPGG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  169 FCILYGGFSRLHLFASEQREEIIKSAIDHAGNYIGISLRIRKEPLEFEQYLNLRFGKYSTDESITSLAEFVVQKISPRHS 248
Cdd:pfam19432  159 FVILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHP 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  249 EPVKRVLALTETCLVERDPATYNIATLKPLGEVFALVCDSENPQLFTIEFIKGQVRKYSSTERDSLLASLLDGVRASGNR 328
Cdd:pfam19432  239 DPVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNR 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  329 DVCVKMTPTHKGQRWGLLSMPVDEEVESLHLRFLATPPNG-NFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNA 407
Cdd:pfam19432  319 DVHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLISPPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVSA 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  408 ITALLSQEGDVVA-SNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGVKVVKALKRSNNGIIHAAVDMLCALMCPMH 486
Cdd:pfam19432  399 LEALLEEEGDQDFiSPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQPMH 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  487 DDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTL 566
Cdd:pfam19432  479 DNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRGRSL 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  567 FKLFQHPSMAIIKGAGLVMKAIIEEGDKEIATKMQELALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNA 646
Cdd:pfam19432  559 FKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWITGNP 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  647 TATNLLKRILPPGLLAYLESSDLVPEKDADRMHVRDNVKIAMDQYGKFNKVPEwqrlagkaakevEKFAKEKVDLVLMHW 726
Cdd:pfam19432  639 DAMDLLKRILPAGLLDYLDSTEEPPEDEEDLLNTRDNLKMATDHSEQKSGLKE------------QKTVEKHVEGLLQHW 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  727 RDRMGIAQKEDKnnmniNQKPVVLRKRRQRIKIEANWDLFYYRFGQDHARSNLIWNFKTREELKDTLESEMRAFNIDREL 806
Cdd:pfam19432  707 RLRIGLEFKKKF-----QQRPVVLRKRRQRVKSEANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKEL 781

                          810       820       830
                   ....*....|....*....|....*....|
gi 1041817999  807 GSANVISWNHHEFEVKYECLAEEIKIGDYY 836
Cdd:pfam19432  782 AGDKVISWNHTEFEVRYPSLADEIKIGDYY 811
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1306-1359 5.73e-16

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 74.05  E-value: 5.73e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFLC 1359
Cdd:pfam00226    1 DYYEILGVSPDA---SDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 981-1031 1.94e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


Pssm-ID: 464112  Cd Length: 50  Bit Score: 72.19  E-value: 1.94e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1041817999  981 WYFGNaDKERSGPYGFHEMQELWTKGMLNAKTRCWAQGMDGWRPLQSIPQL 1031
Cdd:pfam14237    1 WYYAV-NGQQQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 1306-1359 8.05e-15

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 70.65  E-value: 8.05e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGqgpHDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFLC 1359
Cdd:cd06257      1 DYYDILGVPPD---ASDEEIKKAYRKLALKYHPDKNPddpEAEEKFKEINEAYEVLS 54
DnaJ smart00271
DnaJ molecular chaperone homology domain;
1306-1359 1.08e-14

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 70.34  E-value: 1.08e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1041817999  1306 DAYEVLNLPQGqgpHDESKIRKAYFRLAQKYHPDKNP----EGRDMFEKVNKAYEFLC 1359
Cdd:smart00271    2 DYYEILGVPRD---ASLDEIKKAYRKLALKYHPDKNPgdkeEAEEKFKEINEAYEVLS 56
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1301-1360 7.05e-12

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 63.58  E-value: 7.05e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1041817999 1301 MMSIDDAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPDKNPEGRD----MFEKVNKAYEFLCT 1360
Cdd:COG2214      1 MPDLKDHYAVLGVPPDASLEE---IRQAYRRLAKLLHPDRGGELKAlaeeLFQRLNEAYEVLSD 61
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1302-1358 1.13e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 65.94  E-value: 1.13e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK10767     1 MAKRDYYEVLGVSRNA---SEDEIKKAYRKLAMKYHPDRNPgdkEAEEKFKEIKEAYEVL 57
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 1306-1358 3.71e-08

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 58.00  E-value: 3.71e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN--PEGRDMFEKVNKAYEFL 1358
Cdd:TIGR02349    1 DYYEILGVSKDA---SEEEIKKAYRKLAKKYHPDRNkdKEAEEKFKEINEAYEVL 52
 
Name Accession Description Interval E-value
RME-8_N pfam19432
DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in ...
 12-836 0e+00

DNAJ protein RME-8 N-terminal; DNAJ protein RME-8 (receptor-mediated endocytosis-8; Gvr2 in Arabidopsis) is involved in membrane trafficking through early endosomes and in the regulation of endosomal membrane tubulation. It regulates the dynamics of SNX1 (sorting nexin 1) on the endosomal membrane. It coordinates the function of the WASH complex and the retromer SNX dimer through its interaction with FAM21 subunit in WASH complex. This is the N-terminal domain of RME-8, which is required for membrane association and interaction with FAM21 tail domain. It contains critical residues mediating phosphatidylinositol 3-phosphate (PI(3)P) binding, required for its association with endosomes.


Pssm-ID: 466078  Cd Length: 819  Bit Score: 1490.18  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   12 CFYTTKHSWRGKYKRVFSVGTHAITTYNPNTLEVTNQWPYGDICSISPVGKGQG-TEFNLTFRKGsgKKSETLKFSTEHR 90
Cdd:pfam19432    1 CYLVTKHSWKGKYKRIFSIGTLGITTYNPSTLEVTNQWLYSDFISIKPSPKSGGpNEFIITTRKK--GKSDTMRFSSEYR 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999   91 TELLTEALRFRTDFSEGKI--TGRRYNCYKHHWSDSRKPVILEVTPGGFDQINPATNRVLCSYDYRNIEGFVDLSDYQGG 168
Cdd:pfam19432   79 AEILTDALRYRAKFADEYKdkLDQRFNAYKHHWSDRRIPVVLRVTPVGLEQLDPATGEVLASYLYKDIEGIILVSDYPGG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  169 FCILYGGFSRLHLFASEQREEIIKSAIDHAGNYIGISLRIRKEPLEFEQYLNLRFGKYSTDESITSLAEFVVQKISPRHS 248
Cdd:pfam19432  159 FVILYGGFRRLHLFAVENRDELIKKIRENAAEYIGIPIKVAKEPITLDQFKLTRLGKYSSDEHLTSLAEFPVQKISPRHP 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  249 EPVKRVLALTETCLVERDPATYNIATLKPLGEVFALVCDSENPQLFTIEFIKGQVRKYSSTERDSLLASLLDGVRASGNR 328
Cdd:pfam19432  239 DPVRRLLCLSETCLLERDPATYNVVTLRPLKDIFALVRDEEDPQRFSIEYKNGDVRSYTSTERDALLASLLDGVRASGNR 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  329 DVCVKMTPTHKGQRWGLLSMPVDEEVESLHLRFLATPPNG-NFADAVFRFNANISYSGVLHAVTQDGLFSENKEKLINNA 407
Cdd:pfam19432  319 DVHVKMRRTDRGLRLGPLSVPVDEEVESQLLKFLISPPPGgSFADAVERFNANIPYSGLLHSVTQDGLFAENKEKLIVSA 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  408 ITALLSQEGDVVA-SNAELESQFQAVRRLVASKAGFLAFTQLPKFRERLGVKVVKALKRSNNGIIHAAVDMLCALMCPMH 486
Cdd:pfam19432  399 LEALLEEEGDQDFiSPHELEAQFQALRRLFASKAGFSAFTAVPGFREKLGSKVVRALKRNDEAVSHAAVDMLCALMQPMH 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  487 DDYDLRQEQLNKASLLSSKKFLENLLEKFNSHVDHGTGALVISSLLDFLTFALCAPYSETTEGQQFDMLLEMVASNGRTL 566
Cdd:pfam19432  479 DNYDLRQEQLNKSSLLSSKKFLEHLLDMLVDHVERGTGALVVAAMLDFLTFALCAPYSETTDGKQFDSLLEMVADRGRSL 558

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  567 FKLFQHPSMAIIKGAGLVMKAIIEEGDKEIATKMQELALSEGALPRHLHTAMFTISSDQRMLTNRQLSRHLVGLWTADNA 646
Cdd:pfam19432  559 FKLFQHPSLAIVKGAGLVMRAIIEEGDPEISARMQELALSEGALLRHLHTALFTTSRDLRLLTNRQLSRHLIALWITGNP 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  647 TATNLLKRILPPGLLAYLESSDLVPEKDADRMHVRDNVKIAMDQYGKFNKVPEwqrlagkaakevEKFAKEKVDLVLMHW 726
Cdd:pfam19432  639 DAMDLLKRILPAGLLDYLDSTEEPPEDEEDLLNTRDNLKMATDHSEQKSGLKE------------QKTVEKHVEGLLQHW 706

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999  727 RDRMGIAQKEDKnnmniNQKPVVLRKRRQRIKIEANWDLFYYRFGQDHARSNLIWNFKTREELKDTLESEMRAFNIDREL 806
Cdd:pfam19432  707 RLRIGLEFKKKF-----QQRPVVLRKRRQRVKSEANWPMFYYQFKKDHAKPDLIWNHKTREELREALENELRAFNQDKEL 781

                          810       820       830
                   ....*....|....*....|....*....|
gi 1041817999  807 GSANVISWNHHEFEVKYECLAEEIKIGDYY 836
Cdd:pfam19432  782 AGDKVISWNHTEFEVRYPSLADEIKIGDYY 811
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 1306-1359 5.73e-16

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 74.05  E-value: 5.73e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFLC 1359
Cdd:pfam00226    1 DYYEILGVSPDA---SDEEIKKAYRKLALKYHPDKNpgdPEAEEKFKEINEAYEVLS 54
GYF_2 pfam14237
GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately ...
 981-1031 1.94e-15

GYF domain 2; This domain is found in bacteria, archaea and eukaryotes, and is approximately 50 amino acids in length. It contains an evolutionary conserved signature W-X-Y-X6-11-GPF-X4-M-X2-W-X3-GYF, the site of interaction with proline-rich peptides. Family members include RME-8 (Required for receptor-mediated endocytosis 8), a DNAJC13 protein. RME-8 was first identified as a protein that is required for endocytosis in Caenorhabditis elegans. It coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. Family members found in Arabidopsis include Arabidopsis trithorax-related3 (Atxr3), also known as set domain group 2 (Sdg2). It is the major enzyme responsible for H3K4me3 in Arabidopsis and SDG2-dependent H3K4m3 is critical for regulating gene expression and plant development. Another family member found in Arabidopsis is Tic56. It is an essential subunit of a 1-MDa protein complex at the inner chloroplast envelope membrane. Furthermore, Tic56 is important for rRNA processing and chloroplast ribosome assembly.


Pssm-ID: 464112  Cd Length: 50  Bit Score: 72.19  E-value: 1.94e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1041817999  981 WYFGNaDKERSGPYGFHEMQELWTKGMLNAKTRCWAQGMDGWRPLQSIPQL 1031
Cdd:pfam14237    1 WYYAV-NGQQQGPFSLEELRQLAASGEITPDTLVWREGMDDWKPASDVPEL 50
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 1306-1359 8.05e-15

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 70.65  E-value: 8.05e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGqgpHDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFLC 1359
Cdd:cd06257      1 DYYDILGVPPD---ASDEEIKKAYRKLALKYHPDKNPddpEAEEKFKEINEAYEVLS 54
DnaJ smart00271
DnaJ molecular chaperone homology domain;
1306-1359 1.08e-14

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 70.34  E-value: 1.08e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1041817999  1306 DAYEVLNLPQGqgpHDESKIRKAYFRLAQKYHPDKNP----EGRDMFEKVNKAYEFLC 1359
Cdd:smart00271    2 DYYEILGVPRD---ASLDEIKKAYRKLALKYHPDKNPgdkeEAEEKFKEINEAYEVLS 56
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1301-1360 7.05e-12

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 63.58  E-value: 7.05e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1041817999 1301 MMSIDDAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPDKNPEGRD----MFEKVNKAYEFLCT 1360
Cdd:COG2214      1 MPDLKDHYAVLGVPPDASLEE---IRQAYRRLAKLLHPDRGGELKAlaeeLFQRLNEAYEVLSD 61
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 1306-1358 1.77e-11

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 63.95  E-value: 1.77e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQGQGPhDEskIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:COG0484      1 DYYEILGVSRDASA-EE--IKKAYRKLAKKYHPDRNPgdpEAEEKFKEINEAYEVL 53
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 1306-1358 7.43e-11

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 59.63  E-value: 7.43e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQGqGPHDEskIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFL 1358
Cdd:COG5407      1 DPYEVLGVAKT-ASADE--IKKAYRKLAKKYHPDRNkgdPKAEERFKEINEAYELL 53
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1302-1358 1.13e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 65.94  E-value: 1.13e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK10767     1 MAKRDYYEVLGVSRNA---SEDEIKKAYRKLAMKYHPDRNPgdkEAEEKFKEIKEAYEVL 57
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 1301-1358 1.46e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 62.51  E-value: 1.46e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1041817999 1301 MMSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14277     1 MAAKKDYYEILGVDRNA---TEEEIKKAYRRLAKKYHPDLNPgdkEAEQKFKEINEAYEIL 58
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 1306-1358 1.40e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 59.44  E-value: 1.40e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14281     4 DYYEVLGVSRSA---DKDEIKKAYRKLALKYHPDKNPdnkEAEEHFKEVNEAYEVL 56
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 1306-1358 3.02e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 58.24  E-value: 3.02e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1041817999 1306 DAYEVLNLPQgQGPHDEskIRKAYFRLAQKYHPD--KNPEGRDMFEKVNKAYEFL 1358
Cdd:PRK14291     4 DYYEILGVSR-NATQEE--IKKAYRRLARKYHPDfnKNPEAEEKFKEINEAYQVL 55
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 1306-1358 3.71e-08

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 58.00  E-value: 3.71e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN--PEGRDMFEKVNKAYEFL 1358
Cdd:TIGR02349    1 DYYEILGVSKDA---SEEEIKKAYRKLAKKYHPDRNkdKEAEEKFKEINEAYEVL 52
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
1302-1370 5.49e-08

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 51.72  E-value: 5.49e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDK-----NPEGRDMFEK----VNKAYEFLCTKSAKIVDGPD 1370
Cdd:COG1076      1 MQLDDAFELLGLPPDA---DDAELKRAYRKLQREHHPDRlaaglPEEEQRLALQkaaaINEAYETLKDPRGIDLAAPA 75
PRK14297 PRK14297
molecular chaperone DnaJ;
1302-1358 5.98e-08

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 57.49  E-value: 5.98e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14297     1 MASKDYYEVLGLEKGA---SDDEIKKAFRKLAIKYHPDKNKgnkEAEEKFKEINEAYQVL 57
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 1302-1358 7.25e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 53.40  E-value: 7.25e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPD--KNPEGRDMFEKVNKAYEFL 1358
Cdd:PRK14299     1 MAYKDYYAILGVPKNA---SQDEIKKAFKKLARKYHPDvnKSPGAEEKFKEINEAYTVL 56
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 1306-1358 8.87e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 53.69  E-value: 8.87e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14284     2 DYYTILGVSKTASPEE---IKKAYRKLAVKYHPDKNPgdaEAEKRFKEVSEAYEVL 54
PRK14293 PRK14293
molecular chaperone DnaJ;
1301-1358 1.12e-06

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 53.46  E-value: 1.12e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1301 MMSidDAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPD--KNPEGRDMFEKVNKAYEFL 1358
Cdd:PRK14293     1 MAA--DYYEILGVSRDADKDE---LKRAYRRLARKYHPDvnKEPGAEDRFKEINRAYEVL 55
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 1301-1358 1.49e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 52.90  E-value: 1.49e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1301 MMSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN--PEGRDMFEKVNKAYEFL 1358
Cdd:PRK14283     1 MAEKRDYYEVLGVDRNA---DKKEIKKAYRKLARKYHPDVSeeEGAEEKFKEISEAYAVL 57
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 1301-1358 1.75e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 52.54  E-value: 1.75e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1301 MMSIDDAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPDKN--PEGRDMFEKVNKAYEFL 1358
Cdd:PRK14298     1 MATTRDYYEILGLSKDASVED---IKKAYRKLAMKYHPDKNkePDAEEKFKEISEAYAVL 57
PRK14280 PRK14280
molecular chaperone DnaJ;
1302-1358 1.86e-06

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 52.42  E-value: 1.86e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1041817999 1302 MSIDDAYEVLNLPQGqGPHDEskIRKAYFRLAQKYHPDKNPE--GRDMFEKVNKAYEFL 1358
Cdd:PRK14280     1 MAKRDYYEVLGVSKS-ASKDE--IKKAYRKLSKKYHPDINKEegADEKFKEISEAYEVL 56
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 1302-1358 3.94e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 51.63  E-value: 3.94e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN--PEGRDMFEKVNKAYEFL 1358
Cdd:PRK14276     1 MNNTEYYDRLGVSKDA---SQDEIKKAYRKLSKKYHPDINkePGAEEKYKEVQEAYETL 56
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 1306-1359 4.14e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 51.30  E-value: 4.14e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGQGphdESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFLC 1359
Cdd:PRK14294     5 DYYEILGVTRDAS---EEEIKKSYRKLAMKYHPDRNPgdkEAEELFKEAAEAYEVLS 58
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 1308-1358 4.77e-06

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 51.36  E-value: 4.77e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1041817999 1308 YEVLNLPQGQgphDESKIRKAYFRLAQKYHPDK--NPEgrdMFEKVNKAYEFL 1358
Cdd:PTZ00037    31 YEVLNLSKDC---TTSEIKKAYRKLAIKHHPDKggDPE---KFKEISRAYEVL 77
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 1302-1358 5.40e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 51.28  E-value: 5.40e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14301     1 MSQRDYYEVLGVSRDA---SEDEIKKAYRKLALQYHPDRNPdnpEAEQKFKEAAEAYEVL 57
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 1306-1371 7.84e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 50.44  E-value: 7.84e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNP--EGRDMFEKVNKAYEFLCTKSAK-IVD-GPDP 1371
Cdd:PRK14278     4 DYYGLLGVSRNA---SDAEIKRAYRKLARELHPDVNPdeEAQEKFKEISVAYEVLSDPEKRrIVDlGGDP 70
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 1302-1364 1.37e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 50.01  E-value: 1.37e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1041817999 1302 MSIDDAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPD--KNPEGRDMFEKVNKAYEFLCTKSAK 1364
Cdd:PRK14287     1 MSKRDYYEVLGVDRNASVDE---VKKAYRKLARKYHPDvnKAPDAEDKFKEVKEAYDTLSDPQKK 62
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 1306-1358 1.55e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 49.60  E-value: 1.55e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQGqGPHDEskIRKAYFRLAQKYHPDK---NPEGRDMFEKVNKAYEFL 1358
Cdd:PRK14285     4 DYYEILGLSKG-ASKDE--IKKAYRKIAIKYHPDKnkgNKEAESIFKEATEAYEVL 56
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 1306-1358 4.51e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 48.25  E-value: 4.51e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQgQGPHDEskIRKAYFRLAQKYHPDKNPEGR----DMFEKVNKAYEFL 1358
Cdd:PRK14282     5 DYYEILGVSR-NATQEE--IKRAYKRLVKEWHPDRHPENRkeaeQKFKEIQEAYEVL 58
PRK10266 PRK10266
curved DNA-binding protein;
1302-1358 5.23e-05

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 47.51  E-value: 5.23e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLnlpqGQGPHDESK-IRKAYFRLAQKYHPD--KNPEGRDMFEKVNKAYEFL 1358
Cdd:PRK10266     1 MELKDYYAIM----GVKPTDDLKtIKTAYRRLARKYHPDvsKEPDAEARFKEVAEAWEVL 56
PRK14295 PRK14295
molecular chaperone DnaJ;
1306-1358 7.23e-05

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 47.54  E-value: 7.23e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1041817999 1306 DAYEVLNLPQgQGPHDEskIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFL 1358
Cdd:PRK14295    10 DYYKVLGVPK-DATEAE--IKKAYRKLAREYHPDANkgdAKAEERFKEISEAYDVL 62
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 1302-1358 8.09e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 47.29  E-value: 8.09e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFL 1358
Cdd:PRK14286     1 MSERSYYDILGVSKSA---NDEEIKSAYRKLAIKYHPDKNkgnKESEEKFKEATEAYEIL 57
PRK14289 PRK14289
molecular chaperone DnaJ;
1301-1358 8.35e-05

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 47.52  E-value: 8.35e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1041817999 1301 MMSIDDAYEVLNLPQgQGPHDEskIRKAYFRLAQKYHPDKNP---EGRDMFEKVNKAYEFL 1358
Cdd:PRK14289     1 MAEKRDYYEVLGVSK-TATVDE--IKKAYRKKAIQYHPDKNPgdkEAEEKFKEAAEAYDVL 58
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1306-1358 1.46e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 46.42  E-value: 1.46e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1041817999 1306 DAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDKNPE--GRDMFEKVNKAYEFL 1358
Cdd:PRK14292     3 DYYELLGVSRTA---SADEIKSAYRKLALKYHPDRNKEkgAAEKFAQINEAYAVL 54
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 1306-1358 1.51e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 43.38  E-value: 1.51e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1041817999 1306 DAYEVLNLPQGQGPHDeskIRKAYFRLAQKYHPDKNP----EGRDMFEKVNKAYEFL 1358
Cdd:PRK14290     4 DYYKILGVDRNASQED---IKKAFRELAKKWHPDLHPgnkaEAEEKFKEISEAYEVL 57
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 1302-1359 2.09e-03

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 40.22  E-value: 2.09e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1041817999 1302 MSIDDAYEVLNLPQGQgphDESKIRKAYFRLAQKYHPDkNPEGRDMFEKVNKAYEFLC 1359
Cdd:PTZ00100    62 MSKSEAYKILNISPTA---SKERIREAHKQLMLRNHPD-NGGSTYIASKVNEAKDLLL 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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