![](files/infoQ.gif)
myelin transcription factor 1-like protein isoform 5 [Homo sapiens]
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | |||||
MYT1 | pfam08474 | Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ... |
621-872 | 5.44e-122 | |||||
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells. : Pssm-ID: 462489 [Multi-domain] Cd Length: 237 Bit Score: 374.86 E-value: 5.44e-122
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
904-932 | 7.34e-17 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 74.88 E-value: 7.34e-17
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
31-58 | 9.90e-16 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 9.90e-16
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
953-981 | 1.07e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 1.07e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
1007-1034 | 6.82e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 69.10 E-value: 6.82e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
549-577 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
505-531 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. : Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1046-1126 | 1.93e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; : Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.28 E-value: 1.93e-04
|
|||||||||
Name | Accession | Description | Interval | E-value | |||||
MYT1 | pfam08474 | Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ... |
621-872 | 5.44e-122 | |||||
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells. Pssm-ID: 462489 [Multi-domain] Cd Length: 237 Bit Score: 374.86 E-value: 5.44e-122
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
904-932 | 7.34e-17 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 74.88 E-value: 7.34e-17
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
31-58 | 9.90e-16 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 9.90e-16
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
953-981 | 1.07e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 1.07e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
1007-1034 | 6.82e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 69.10 E-value: 6.82e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
549-577 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
505-531 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1046-1126 | 1.93e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.28 E-value: 1.93e-04
|
|||||||||
CCDC22 | pfam05667 | Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
1039-1117 | 7.09e-04 | |||||
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants. Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.86 E-value: 7.09e-04
|
|||||||||
Mplasa_alph_rch | TIGR04523 | helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1060-1138 | 9.63e-04 | |||||
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown. Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 9.63e-04
|
|||||||||
Atg16_CCD | cd22887 | Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1062-1108 | 2.43e-03 | |||||
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins. Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 38.32 E-value: 2.43e-03
|
|||||||||
Name | Accession | Description | Interval | E-value | |||||
MYT1 | pfam08474 | Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ... |
621-872 | 5.44e-122 | |||||
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells. Pssm-ID: 462489 [Multi-domain] Cd Length: 237 Bit Score: 374.86 E-value: 5.44e-122
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
904-932 | 7.34e-17 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 74.88 E-value: 7.34e-17
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
31-58 | 9.90e-16 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 9.90e-16
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
953-981 | 1.07e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 71.41 E-value: 1.07e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
1007-1034 | 6.82e-15 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 69.10 E-value: 6.82e-15
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
549-577 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
zf-C2HC | pfam01530 | Zinc finger, C2HC type; This is a DNA binding zinc finger domain. |
505-531 | 4.84e-14 | |||||
Zinc finger, C2HC type; This is a DNA binding zinc finger domain. Pssm-ID: 460240 Cd Length: 29 Bit Score: 66.79 E-value: 4.84e-14
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1046-1126 | 1.93e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.28 E-value: 1.93e-04
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1063-1128 | 3.19e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.51 E-value: 3.19e-04
|
|||||||||
CCDC22 | pfam05667 | Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
1039-1117 | 7.09e-04 | |||||
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants. Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.86 E-value: 7.09e-04
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1063-1127 | 7.34e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.35 E-value: 7.34e-04
|
|||||||||
Mplasa_alph_rch | TIGR04523 | helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1060-1138 | 9.63e-04 | |||||
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown. Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 9.63e-04
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1063-1128 | 9.95e-04 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 9.95e-04
|
|||||||||
COG4372 | COG4372 | Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1060-1128 | 1.31e-03 | |||||
Uncharacterized protein, contains DUF3084 domain [Function unknown]; Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.58 E-value: 1.31e-03
|
|||||||||
Mplasa_alph_rch | TIGR04523 | helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1050-1129 | 1.62e-03 | |||||
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown. Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 1.62e-03
|
|||||||||
Atg16_CCD | cd22887 | Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1062-1108 | 2.43e-03 | |||||
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins. Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 38.32 E-value: 2.43e-03
|
|||||||||
EnvC | COG4942 | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1060-1128 | 3.80e-03 | |||||
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 3.80e-03
|
|||||||||
YhaN | COG4717 | Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1037-1128 | 6.16e-03 | |||||
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 6.16e-03
|
|||||||||
EnvC | COG4942 | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1051-1124 | 6.66e-03 | |||||
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 6.66e-03
|
|||||||||
FapA | pfam03961 | Flagellar Assembly Protein A beta solenoid domain; This entry represents the C-terminal beta ... |
1057-1135 | 9.89e-03 | |||||
Flagellar Assembly Protein A beta solenoid domain; This entry represents the C-terminal beta solenoid domain of FapA and its homologs. Members of this family include FapA (flagellar assembly protein A) found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction. This entry shows similarity to pfam03775 suggesting a similar functional role. Pssm-ID: 461111 [Multi-domain] Cd Length: 272 Bit Score: 39.21 E-value: 9.89e-03
|
|||||||||
Blast search parameters | ||||
|