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Conserved domains on  [gi|1164769123|ref|NP_001336584|]
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progesterone-induced-blocking factor 1 isoform 1 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
208-567 1.61e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  208 LAEELSTNKNQLK---QLTETYEEDRKNYSEVQircqrLALELADTKQLiqqgdyrQENYDKVKSERDALEQEVIELRRK 284
Cdd:TIGR02168  194 ILNELERQLKSLErqaEKAERYKELKAELRELE-----LALLVLRLEEL-------REELEELQEELKEAEEELEELTAE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  285 HEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKyva 364
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE--- 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  365 srdhykteyENKLHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQYLRtgiwqepshyiiiwhkARRNLREARd 444
Cdd:TIGR02168  339 ---------LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----------------LRSKVAQLE- 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  445 navaEKERAVMAEKDALEKHDQLLDRYRELQLSTESKvteflHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKL 524
Cdd:TIGR02168  393 ----LQIASLNNEIERLEARLERLEDRRERLQQEIEE-----LLKKLEEAELKELQAELEELEEELEELQEELERLEEAL 463
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1164769123  525 EVLTKEFyslqASSEKRITELQAQNSEHQARLDIYEKLEKELD 567
Cdd:TIGR02168  464 EELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLE 502
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
32-355 2.62e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 2.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   32 DDISSSEEREGKVRITRQLIERKELlhNIQLLKIELSQKTMMIDNLKVDYLTKIE--ELEEKLNDA---LHQKQLLTLR- 105
Cdd:TIGR02169  160 DEIAGVAEFDRKKEKALEELEEVEE--NIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYegyELLKEKEALEr 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  106 ----LDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGD----VRRNLRDFELTEEQYIKLKAFPEDQL 177
Cdd:TIGR02169  238 qkeaIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKEREL 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  178 SIPEYVSVRFYELVNPLRKEICElqvkkniLAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQg 257
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEE-------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD- 389
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  258 dyRQENYDKVKSERDAL--------------EQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYL 323
Cdd:TIGR02169  390 --YREKLEKLKREINELkreldrlqeelqrlSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
                          330       340       350
                   ....*....|....*....|....*....|..
gi 1164769123  324 NRQNMELSVRCAHEEDRLERLQAQLEESKKAR 355
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
433-723 4.80e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 4.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 433 HKARRNLREARDN----------------------AVAEKERAVMAEKDALEkHDQLLDRYRELQlsteSKVTEFLHQSK 490
Cdd:COG1196   175 EEAERKLEATEENlerledilgelerqleplerqaEKAERYRELKEELKELE-AELLLLKLRELE----AELEELEAELE 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 491 LKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEII 570
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 571 MQTAEIENEDEAERvlfsygygANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQ 650
Cdd:COG1196   330 EELEELEEELEELE--------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1164769123 651 TQQpyryLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQILVK 723
Cdd:COG1196   402 LEE----LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
208-567 1.61e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  208 LAEELSTNKNQLK---QLTETYEEDRKNYSEVQircqrLALELADTKQLiqqgdyrQENYDKVKSERDALEQEVIELRRK 284
Cdd:TIGR02168  194 ILNELERQLKSLErqaEKAERYKELKAELRELE-----LALLVLRLEEL-------REELEELQEELKEAEEELEELTAE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  285 HEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKyva 364
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE--- 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  365 srdhykteyENKLHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQYLRtgiwqepshyiiiwhkARRNLREARd 444
Cdd:TIGR02168  339 ---------LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----------------LRSKVAQLE- 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  445 navaEKERAVMAEKDALEKHDQLLDRYRELQLSTESKvteflHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKL 524
Cdd:TIGR02168  393 ----LQIASLNNEIERLEARLERLEDRRERLQQEIEE-----LLKKLEEAELKELQAELEELEEELEELQEELERLEEAL 463
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1164769123  525 EVLTKEFyslqASSEKRITELQAQNSEHQARLDIYEKLEKELD 567
Cdd:TIGR02168  464 EELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
206-569 3.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 3.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 206 NILAEELSTNKNQLK---QLTETYEEDRKNYSEVQIRCQRLALELADTKQ--LIQQGDYRQENYDKVKSERDALEQEVIE 280
Cdd:COG1196   192 EDILGELERQLEPLErqaEKAERYRELKEELKELEAELLLLKLRELEAELeeLEAELEELEAELEELEAELAELEAELEE 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 281 LRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEmye 360
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE--- 348
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 361 kyvasrdhykteyenkLHDELEQIRLKTNQEIDQLRNASREMYERENRsggwevqylrtgiwqepshyiiiwhkarrnlR 440
Cdd:COG1196   349 ----------------AEEELEEAEAELAEAEEALLEAEAELAEAEEE-------------------------------L 381
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 441 EARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKY 520
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1164769123 521 QKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 569
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
32-355 2.62e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 2.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   32 DDISSSEEREGKVRITRQLIERKELlhNIQLLKIELSQKTMMIDNLKVDYLTKIE--ELEEKLNDA---LHQKQLLTLR- 105
Cdd:TIGR02169  160 DEIAGVAEFDRKKEKALEELEEVEE--NIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYegyELLKEKEALEr 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  106 ----LDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGD----VRRNLRDFELTEEQYIKLKAFPEDQL 177
Cdd:TIGR02169  238 qkeaIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKEREL 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  178 SIPEYVSVRFYELVNPLRKEICElqvkkniLAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQg 257
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEE-------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD- 389
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  258 dyRQENYDKVKSERDAL--------------EQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYL 323
Cdd:TIGR02169  390 --YREKLEKLKREINELkreldrlqeelqrlSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
                          330       340       350
                   ....*....|....*....|....*....|..
gi 1164769123  324 NRQNMELSVRCAHEEDRLERLQAQLEESKKAR 355
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
433-723 4.80e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 4.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 433 HKARRNLREARDN----------------------AVAEKERAVMAEKDALEkHDQLLDRYRELQlsteSKVTEFLHQSK 490
Cdd:COG1196   175 EEAERKLEATEENlerledilgelerqleplerqaEKAERYRELKEELKELE-AELLLLKLRELE----AELEELEAELE 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 491 LKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEII 570
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 571 MQTAEIENEDEAERvlfsygygANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQ 650
Cdd:COG1196   330 EELEELEEELEELE--------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1164769123 651 TQQpyryLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQILVK 723
Cdd:COG1196   402 LEE----LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
433-763 6.93e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 6.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  433 HKARRNLREARDN------AVAEKERAV---MAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFES-ERVQLL 502
Cdd:TIGR02168  175 KETERKLERTRENldrledILNELERQLkslERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEElKEAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  503 QEETARNLTQCQLECE-------KYQKKLEVLTKEFYSLQAssekRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAE 575
Cdd:TIGR02168  255 LEELTAELQELEEKLEelrlevsELEEEIEELQKELYALAN----EISRLEQQKQILRERLANLERQLEELEAQLEELES 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  576 IENEDEAErvlfsygyganvpttAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPY 655
Cdd:TIGR02168  331 KLDELAEE---------------LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  656 RYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDL--EQLLNHREELAAMKQILVKMHSKHSENSL 733
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEleEELEELQEELERLEEALEELREELEEAEQ 475
                          330       340       350
                   ....*....|....*....|....*....|
gi 1164769123  734 LLTKTEPKHVTENQKSKTLNVPKEHEDNIF 763
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFS 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
124-566 7.16e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 7.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 124 MKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAfpedQLSIPEYVSVRFYELVNPLRKEICELQV 203
Cdd:PRK03918  198 KEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK----ELESLEGSKRKLEEKIRELEERIEELKK 273
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 204 KKNILaEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRR 283
Cdd:PRK03918  274 EIEEL-EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEK 352
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 284 KHEILEASHMIQTKERSELS-----------KEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESK 352
Cdd:PRK03918  353 RLEELEERHELYEEAKAKKEelerlkkrltgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK 432
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 353 KA---------------REEMYEKY------VASRDHYKTEYENKLHDELEQIR--LKTNQEIDQLRNASREMYERENRS 409
Cdd:PRK03918  433 KAkgkcpvcgrelteehRKELLEEYtaelkrIEKELKEIEEKERKLRKELRELEkvLKKESELIKLKELAEQLKELEEKL 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 410 GGWEVQYLRTGiWQE----PSHYIIIWHKARRNLREARDNAVAEKERAVMAEK--DALEKHDQLLDRYRELQLSTESKVT 483
Cdd:PRK03918  513 KKYNLEELEKK-AEEyeklKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKldELEEELAELLKELEELGFESVEELE 591
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 484 EFLhqSKLKSFESERVQLLQ-----EETARNLTQCQLECEKYQKKLEVLTKEFYSLqassEKRITELQAQNS--EHQARL 556
Cdd:PRK03918  592 ERL--KELEPFYNEYLELKDaekelEREEKELKKLEEELDKAFEELAETEKRLEEL----RKELEELEKKYSeeEYEELR 665
                         490
                  ....*....|
gi 1164769123 557 DIYEKLEKEL 566
Cdd:PRK03918  666 EEYLELSREL 675
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
141-721 1.77e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 1.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  141 TNLQLREKAGDVRRNLRDFElTEEQYIKLKAFP-EDQLSIPEYVSVRFYELVnplrkeiceLQVKKNILAEELSTNKNQL 219
Cdd:pfam15921  211 STMHFRSLGSAISKILRELD-TEISYLKGRIFPvEDQLEALKSESQNKIELL---------LQQHQDRIEQLISEHEVEI 280
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  220 KQLTETYEEDRKNYSEVQIRCQrlaleladtkqlIQQGDYRQENYDKVKSERDaLEQEVIELRRkhEILEASHMIQTKeR 299
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLE------------IIQEQARNQNSMYMRQLSD-LESTVSQLRS--ELREAKRMYEDK-I 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  300 SELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASR---DHYKTEYENK 376
Cdd:pfam15921  345 EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSitiDHLRRELDDR 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  377 ------LHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQYLRTgiwQEPSHYIIIWHKARRNLREARDNAVA-- 448
Cdd:pfam15921  425 nmevqrLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST---KEMLRKVVEELTAKKMTLESSERTVSdl 501
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  449 -----EKERAVMAEKDALEKHDQLLD-RYRELQ-LSTESKVTEFLHQS----KLKSFESERVQLLQEETARNLTQ----- 512
Cdd:pfam15921  502 taslqEKERAIEATNAEITKLRSRVDlKLQELQhLKNEGDHLRNVQTEcealKLQMAEKDKVIEILRQQIENMTQlvgqh 581
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  513 -----------CQLECEKYQKKLEVltKEFYSLQASSEKRITELQAQNSEHQ-----------ARLDIYEKLEKELDEII 570
Cdd:pfam15921  582 grtagamqvekAQLEKEINDRRLEL--QEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVKDIKQERDQLL 659
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  571 MQTAEIENE-----DEAERVLFSYGYGANVPTTAKRRLKQSVHLARRVLQlekQNSLILKDLEHRKDQVTQLSQELDRan 645
Cdd:pfam15921  660 NEVKTSRNElnslsEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE---QTRNTLKSMEGSDGHAMKVAMGMQK-- 734
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1164769123  646 sllnqtqqpyrylieSVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQIL 721
Cdd:pfam15921  735 ---------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVL 795
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
208-567 1.61e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  208 LAEELSTNKNQLK---QLTETYEEDRKNYSEVQircqrLALELADTKQLiqqgdyrQENYDKVKSERDALEQEVIELRRK 284
Cdd:TIGR02168  194 ILNELERQLKSLErqaEKAERYKELKAELRELE-----LALLVLRLEEL-------REELEELQEELKEAEEELEELTAE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  285 HEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKyva 364
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE--- 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  365 srdhykteyENKLHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQYLRtgiwqepshyiiiwhkARRNLREARd 444
Cdd:TIGR02168  339 ---------LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----------------LRSKVAQLE- 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  445 navaEKERAVMAEKDALEKHDQLLDRYRELQLSTESKvteflHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKL 524
Cdd:TIGR02168  393 ----LQIASLNNEIERLEARLERLEDRRERLQQEIEE-----LLKKLEEAELKELQAELEELEEELEELQEELERLEEAL 463
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1164769123  525 EVLTKEFyslqASSEKRITELQAQNSEHQARLDIYEKLEKELD 567
Cdd:TIGR02168  464 EELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLE 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
125-404 6.22e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 6.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  125 KQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQVK 204
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  205 KNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQ--QGDYRQEN--YDKVKSERDALEQEVIE 280
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDelRAELTLLNeeAANLRERLESLERRIAA 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  281 LRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYE 360
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRR 915
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1164769123  361 KYVASRDHykteyENKLHDELEQIRLKTNQEIDQLRNASREMYE 404
Cdd:TIGR02168  916 ELEELREK-----LAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
206-569 3.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 3.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 206 NILAEELSTNKNQLK---QLTETYEEDRKNYSEVQIRCQRLALELADTKQ--LIQQGDYRQENYDKVKSERDALEQEVIE 280
Cdd:COG1196   192 EDILGELERQLEPLErqaEKAERYRELKEELKELEAELLLLKLRELEAELeeLEAELEELEAELEELEAELAELEAELEE 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 281 LRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEmye 360
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE--- 348
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 361 kyvasrdhykteyenkLHDELEQIRLKTNQEIDQLRNASREMYERENRsggwevqylrtgiwqepshyiiiwhkarrnlR 440
Cdd:COG1196   349 ----------------AEEELEEAEAELAEAEEALLEAEAELAEAEEE-------------------------------L 381
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 441 EARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKY 520
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1164769123 521 QKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 569
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
17-717 7.85e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 7.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   17 SLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVDYLTKIEELEEKLNDAL 96
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   97 HQKQLLTLRLdNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEE----QYIKLKAF 172
Cdd:TIGR02168  330 SKLDELAEEL-AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAslnnEIERLEAR 408
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  173 PED-QLSIPEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTK 251
Cdd:TIGR02168  409 LERlEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  252 QLIQQGDYRQENYDKVKSERDALEQEVIELRRKHEILeaSHMIQTKERSELSKEVVTLEQTVTLLQKDKE-------YLN 324
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL--SELISVDEGYEAAIEAALGGRLQAVVVENLNaakkaiaFLK 566
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  325 RQNMELSVRCAHEEDRLERLQAQLEESKKaREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNqeIDQLRNASREMYE 404
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREILK-NIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD--LDNALELAKKLRP 643
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  405 REN---------RSGGwevqyLRTGIWQEPSHYIIIWHKARRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQ 475
Cdd:TIGR02168  644 GYRivtldgdlvRPGG-----VITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  476 LSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKrITELQAQnsehqar 555
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE-IEELEAQ------- 790
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  556 ldiYEKLEKELDEIIMQTAEIENEDEAERVLFsygygANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVT 635
Cdd:TIGR02168  791 ---IEQLKEELKALREALDELRAELTLLNEEA-----ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  636 QLSQELDRANSLLNQTQQPYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELA 715
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                   ..
gi 1164769123  716 AM 717
Cdd:TIGR02168  943 ER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
87-696 1.03e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  87 ELEEKLNDALHQKQLLTLR-LDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQ 165
Cdd:COG1196   217 ELKEELKELEAELLLLKLReLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 166 YIKLKafpedqlsipeyvsvrfyELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLAL 245
Cdd:COG1196   297 LARLE------------------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 246 ELADTKQ----LIQQGDYRQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE 321
Cdd:COG1196   359 ELAEAEEalleAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 322 YLNRQNMELsvrcAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQEidQLRNASRE 401
Cdd:COG1196   439 EEEEALEEA----AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE--GFLEGVKA 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 402 MYERENRSGGWEVQYLRTGIWQEPSHYIIIWHKARRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESK 481
Cdd:COG1196   513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 482 VTEF------LHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKK------LEVLTKEFYSLQASSEKRITELQAQN 549
Cdd:COG1196   593 ARGAigaavdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVtlagrlREVTLEGEGGSAGGSLTGGSRRELLA 672
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 550 SEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERvlfsygyganvptTAKRRLKQSVHLARRVLQLEKQNSLILKDLEH 629
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEER-------------ELAEAEEERLEEELEEEALEEQLEAEREELLE 739
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 630 RKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQR-------------------------DSKIDSLTESIAQLEKDVS 684
Cdd:COG1196   740 ELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllaieeyeeleerydflSEQREDLEEARETLEEAIE 819
                         650
                  ....*....|..
gi 1164769123 685 NLNKEKSALLQT 696
Cdd:COG1196   820 EIDRETRERFLE 831
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
32-355 2.62e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 2.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   32 DDISSSEEREGKVRITRQLIERKELlhNIQLLKIELSQKTMMIDNLKVDYLTKIE--ELEEKLNDA---LHQKQLLTLR- 105
Cdd:TIGR02169  160 DEIAGVAEFDRKKEKALEELEEVEE--NIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYegyELLKEKEALEr 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  106 ----LDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGD----VRRNLRDFELTEEQYIKLKAFPEDQL 177
Cdd:TIGR02169  238 qkeaIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKEREL 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  178 SIPEYVSVRFYELVNPLRKEICElqvkkniLAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQg 257
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEE-------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD- 389
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  258 dyRQENYDKVKSERDAL--------------EQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYL 323
Cdd:TIGR02169  390 --YREKLEKLKREINELkreldrlqeelqrlSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
                          330       340       350
                   ....*....|....*....|....*....|..
gi 1164769123  324 NRQNMELSVRCAHEEDRLERLQAQLEESKKAR 355
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
90-716 3.63e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 3.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   90 EKLNDALHQ--KQLLTLRLdnqlafQQKDASKYQELmKQEMETILLR---------QKQLEETNLQLREKAGDVRRNLRD 158
Cdd:TIGR02168  189 DRLEDILNEleRQLKSLER------QAEKAERYKEL-KAELRELELAllvlrleelREELEELQEELKEAEEELEELTAE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  159 FELTEEQYIKLK-AFPEDQLSIPEYVSvRFYELVNplrkEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQ 237
Cdd:TIGR02168  262 LQELEEKLEELRlEVSELEEEIEELQK-ELYALAN----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  238 IRCQRLALELADTKQLIQQgdyRQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQ 317
Cdd:TIGR02168  337 EELAELEEKLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  318 KDKEYLNRQNMELsvRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKlhDELEQIRLKTNQEIDQLRN 397
Cdd:TIGR02168  414 DRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL--EEAEQALDAAERELAQLQA 489
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  398 ASREMYERENRSGG--------WEVQYLRTGIWQEPSHYIII---WHKARRN-LREARDNAVAEKERAVMAEKDALEKHD 465
Cdd:TIGR02168  490 RLDSLERLQENLEGfsegvkalLKNQSGLSGILGVLSELISVdegYEAAIEAaLGGRLQAVVVENLNAAKKAIAFLKQNE 569
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  466 QLLDRYRELQLSTESKVtEFLHQSKLKSFESERVQLLQEET------------------ARNLTQCQLECEKYQKKLEVL 527
Cdd:TIGR02168  570 LGRVTFLPLDSIKGTEI-QGNDREILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvVDDLDNALELAKKLRPGYRIV 648
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  528 TKEFYSLQAS------SEKRITELQAQNSEhqarldiYEKLEKELDEIIMQTAEIENE-DEAERVLFSYGYGANVPTTAK 600
Cdd:TIGR02168  649 TLDGDLVRPGgvitggSAKTNSSILERRRE-------IEELEEKIEELEEKIAELEKAlAELRKELEELEEELEQLRKEL 721
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  601 RRLKQSVHLAR--------RVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQRDSKIDSL 672
Cdd:TIGR02168  722 EELSRQISALRkdlarleaEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1164769123  673 TESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAA 716
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
433-723 4.80e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 4.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 433 HKARRNLREARDN----------------------AVAEKERAVMAEKDALEkHDQLLDRYRELQlsteSKVTEFLHQSK 490
Cdd:COG1196   175 EEAERKLEATEENlerledilgelerqleplerqaEKAERYRELKEELKELE-AELLLLKLRELE----AELEELEAELE 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 491 LKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEII 570
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 571 MQTAEIENEDEAERvlfsygygANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQ 650
Cdd:COG1196   330 EELEELEEELEELE--------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1164769123 651 TQQpyryLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQILVK 723
Cdd:COG1196   402 LEE----LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
36-409 1.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   36 SSEEREGKVRITRQLIERKELLHNIQLLKIELS---QKTMMIDNLKVDYLTKIEELEEKLNDALHQKQLLTLRLDNQLAF 112
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSslqSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER 738
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  113 QQKDASKYQEL------MKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQyiklkafpeDQLSIPEYVSVR 186
Cdd:TIGR02169  739 LEELEEDLSSLeqeienVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQ---------AELSKLEEEVSR 809
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  187 FYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDyrqENYDK 266
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE---SRLGD 886
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  267 VKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSV--RCAHEEDRLERL 344
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSleDVQAELQRVEEE 966
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1164769123  345 QAQLEESKKAREEMYEKYVASRDHYKtEYENKLHDELEQIRLKTNQEIDQLRNASREMYERENRS 409
Cdd:TIGR02169  967 IRALEPVNMLAIQEYEEVLKRLDELK-EKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINEN 1030
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
37-356 1.51e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   37 SEEREGKVRITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVDyLTKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKD 116
Cdd:TIGR02168  691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  117 ASKYQELMKQEMETILLRQKQLEETNLQ----------LREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVR 186
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEElkalrealdeLRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  187 FYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDK 266
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL 929
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  267 VKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVvtLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQA 346
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE--ARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTA 1007
                          330
                   ....*....|
gi 1164769123  347 QLEESKKARE 356
Cdd:TIGR02168 1008 QKEDLTEAKE 1017
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
125-357 3.84e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 3.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 125 KQEMETIllrQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLkafpEDQLSIPEyvsvrfyELVNPLRKEICELQVK 204
Cdd:COG4942    26 EAELEQL---QQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALE-------QELAALEAELAELEKE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 205 KNILAEELSTNKNQL-KQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRR 283
Cdd:COG4942    92 IAELRAELEAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1164769123 284 KHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELsvrcAHEEDRLERLQAQLEESKKAREE 357
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL----QQEAEELEALIARLEAEAAAAAE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
433-763 6.93e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 6.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  433 HKARRNLREARDN------AVAEKERAV---MAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFES-ERVQLL 502
Cdd:TIGR02168  175 KETERKLERTRENldrledILNELERQLkslERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEElKEAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  503 QEETARNLTQCQLECE-------KYQKKLEVLTKEFYSLQAssekRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAE 575
Cdd:TIGR02168  255 LEELTAELQELEEKLEelrlevsELEEEIEELQKELYALAN----EISRLEQQKQILRERLANLERQLEELEAQLEELES 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  576 IENEDEAErvlfsygyganvpttAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPY 655
Cdd:TIGR02168  331 KLDELAEE---------------LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  656 RYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDL--EQLLNHREELAAMKQILVKMHSKHSENSL 733
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEleEELEELQEELERLEEALEELREELEEAEQ 475
                          330       340       350
                   ....*....|....*....|....*....|
gi 1164769123  734 LLTKTEPKHVTENQKSKTLNVPKEHEDNIF 763
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFS 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
242-584 8.79e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 8.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  242 RLALELADTKQLIQQGdyrQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE 321
Cdd:TIGR02168  681 ELEEKIEELEEKIAEL---EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  322 YLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRdhykteyenKLHDELEQIRLKTNQEIDQLRNAsRE 401
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR---------EALDELRAELTLLNEEAANLRER-LE 827
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  402 MYERENRSGGWEVQYLrtgiwqepshyiiiwHKARRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESK 481
Cdd:TIGR02168  828 SLERRIAATERRLEDL---------------EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  482 VTEF-LHQSKLKSFESERVQLLQEetarnLTQCQLECEKYQKKLEVLTKEFYSLQAS-SEKRITELQAQNSEHQARLDIY 559
Cdd:TIGR02168  893 RSELeELSEELRELESKRSELRRE-----LEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDE 967
                          330       340       350
                   ....*....|....*....|....*....|....
gi 1164769123  560 EKLEKELDEIIMQTAEI---------ENEDEAER 584
Cdd:TIGR02168  968 EEARRRLKRLENKIKELgpvnlaaieEYEELKER 1001
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
183-579 1.01e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  183 VSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQgdyrqe 262
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE------ 741
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  263 nydkVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQT-----VTLLQKDKEYLNRQNMELSVRCAHE 337
Cdd:TIGR02169  742 ----LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsrIPEIQAELSKLEEEVSRIEARLREI 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  338 EDRLERLQAQLEESKKAREEMyEKYVASRDHYKTEYENKLHDELEQIRlKTNQEIDQLRNASREMYERenrsggwevqyl 417
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQEL-QEQRIDLKEQIKSIEKEIENLNGKKE-ELEEELEELEAALRDLESR------------ 883
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  418 rtgiwqepshyiiiwhkaRRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKvteflhQSKLKSFESE 497
Cdd:TIGR02169  884 ------------------LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAL------EEELSEIEDP 939
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  498 RVQLLQEetarnlTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQaqnsEHQARLDIYE----KLEKELDEIIMQT 573
Cdd:TIGR02169  940 KGEDEEI------PEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYE----EVLKRLDELKekraKLEEERKAILERI 1009

                   ....*.
gi 1164769123  574 AEIENE 579
Cdd:TIGR02169 1010 EEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
218-696 1.05e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  218 QLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYR--QENYDKVKSERDALEQEVIELRRKHEILEASHM-I 294
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALREELDELEAQIRgN 335
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  295 QTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQL--------EESKKAREEMYEKYVASR 366
Cdd:COG4913    336 GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAaallealeEELEALEEALAEAEAALR 415
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  367 DHyKTEYEnKLHDELEQIRLKTN---QEIDQLRNASR-----------------EMYERENRsggWE---VQYL---RTG 420
Cdd:COG4913    416 DL-RRELR-ELEAEIASLERRKSnipARLLALRDALAealgldeaelpfvgeliEVRPEEER---WRgaiERVLggfALT 490
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  421 IWQEPSHY-----IIIWHKARRNLREARDNAVAEKERAVMAEKDALekhdqlldrYRELQLStESKVTEFLHQSKLKSFE 495
Cdd:COG4913    491 LLVPPEHYaaalrWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSL---------AGKLDFK-PHPFRAWLEAELGRRFD 560
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  496 SERVQLLQE--ETARNLT-QCQL--ECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDiyeKLEKELDEII 570
Cdd:COG4913    561 YVCVDSPEElrRHPRAITrAGQVkgNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELA---EAEERLEALE 637
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  571 MQTAEIENEDEAERVLFSYGYganvpttAKRRLKQsvhLARRVLQLEKQnsliLKDLEHRKDQVTQLSQELDRANSLLNQ 650
Cdd:COG4913    638 AELDALQERREALQRLAEYSW-------DEIDVAS---AEREIAELEAE----LERLDASSDDLAALEEQLEELEAELEE 703
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1164769123  651 TQQPYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQT 696
Cdd:COG4913    704 LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
194-379 1.30e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  194 LRKEICELQVKKNILAEELSTNKNQLKQLTETYE--EDRKNYSEVQIRCQRLALELADTKQLIQQ-----GDYR--QENY 264
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERldassDDLAalEEQL 694
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  265 DKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQkdKEYLNRQNMELSVRcAHEEDRLERL 344
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL--RALLEERFAAALGD-AVERELRENL 771
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1164769123  345 QAQLEESKKAREEMYEKYVASRDHYKTEYENKLHD 379
Cdd:COG4913    772 EERIDALRARLNRAEEELERAMRAFNREWPAETAD 806
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
87-717 1.63e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   87 ELEEKLNDAlhQKQLLTLRLD---NQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKA----------GDVR 153
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEelrEELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEeeieelqkelYALA 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  154 RNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFY-------ELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETY 226
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELEskldelaEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  227 EED-------RKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSE--RDALEQEVIELRRKHEILEASHMIQTK 297
Cdd:TIGR02168  375 EELeeqletlRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQE 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  298 ERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQaqlEESKKAREEMYEKYVASRDH--------- 368
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE---GFSEGVKALLKNQSGLSGILgvlselisv 531
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  369 ---YKTEYENKLHDELEQIRLKTNQEIDQLRNAsremyERENRSGGWEVQYLRTGIWQEPSHYIIIWHKARRNLREARDN 445
Cdd:TIGR02168  532 degYEAAIEAALGGRLQAVVVENLNAAKKAIAF-----LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD 606
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  446 AVAEKERAVMAEKDAL------EKHDQLLDRYRELQLStESKVT---EFLHQSKLKSFESERVQLLQEETARNLTQCQLE 516
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRPG-YRIVTldgDLVRPGGVITGGSAKTNSSILERRREIEELEEK 685
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  517 CEKYQ-------KKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKE----LDEIIMQTAEIENEDEAERV 585
Cdd:TIGR02168  686 IEELEekiaeleKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqlEERIAQLSKELTELEAEIEE 765
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  586 LFSYGYGANvpTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQR 665
Cdd:TIGR02168  766 LEERLEEAE--EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1164769123  666 DSKIDSLTESIAQLEKDVSNL----NKEKSALLQTKNQMALDLEQLLNHREELAAM 717
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELeeliEELESELEALLNERASLEEALALLRSELEEL 899
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
113-716 2.00e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 113 QQKDASKYQELMKQEMET-ILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAfpedqlsipeyvsvrfyeLV 191
Cdd:COG1196   208 QAEKAERYRELKEELKELeAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA------------------EL 269
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 192 NPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQgdyrqenydkVKSER 271
Cdd:COG1196   270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE----------LEEEL 339
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 272 DALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEES 351
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 352 KKAREEMYEKYVASRdhyktEYENKLHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQylrtgiwqepshyiii 431
Cdd:COG1196   420 EEELEELEEALAELE-----EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA---------------- 478
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 432 WHKARRNLREARDNAVAEKERAVMAE---KDALEKHDQLLDRYRELQLSTESKVtEFLHQSKLKSFESERVQLLQEETAR 508
Cdd:COG1196   479 LAELLEELAEAAARLLLLLEAEADYEgflEGVKAALLLAGLRGLAGAVAVLIGV-EAAYEAALEAALAAALQNIVVEDDE 557
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 509 NLtqcqLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAErvlfs 588
Cdd:COG1196   558 VA----AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV----- 628
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 589 ygygANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQpyRYLIESVRQRDSK 668
Cdd:COG1196   629 ----AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA--EEELELEEALLAE 702
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 1164769123 669 IDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAA 716
Cdd:COG1196   703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
503-716 3.36e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 3.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 503 QEETARNLTQCQLECEKYQKKLEVLTKEFYSLQ---ASSEKRITELQAQNSEHQARLdiyEKLEKELDEIIMQTAEIENE 579
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLkqlAALERRIAALARRIRALEQEL---AALEAELAELEKEIAELRAE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 580 DE------AERVLFSYGYGANVPTTAKRRLKQSVHLARRVLQLEKQNslilkdlEHRKDQVTQLSQELDRANSLLNQTQQ 653
Cdd:COG4942    99 LEaqkeelAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA-------PARREQAEELRADLAELAALRAELEA 171
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1164769123 654 PYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSAL---LQTKNQMALDLEQLLNHREELAA 716
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELaaeLAELQQEAEELEALIARLEAEAA 237
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
124-566 7.16e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 7.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 124 MKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAfpedQLSIPEYVSVRFYELVNPLRKEICELQV 203
Cdd:PRK03918  198 KEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEK----ELESLEGSKRKLEEKIRELEERIEELKK 273
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 204 KKNILaEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRR 283
Cdd:PRK03918  274 EIEEL-EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEK 352
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 284 KHEILEASHMIQTKERSELS-----------KEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESK 352
Cdd:PRK03918  353 RLEELEERHELYEEAKAKKEelerlkkrltgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK 432
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 353 KA---------------REEMYEKY------VASRDHYKTEYENKLHDELEQIR--LKTNQEIDQLRNASREMYERENRS 409
Cdd:PRK03918  433 KAkgkcpvcgrelteehRKELLEEYtaelkrIEKELKEIEEKERKLRKELRELEkvLKKESELIKLKELAEQLKELEEKL 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 410 GGWEVQYLRTGiWQE----PSHYIIIWHKARRNLREARDNAVAEKERAVMAEK--DALEKHDQLLDRYRELQLSTESKVT 483
Cdd:PRK03918  513 KKYNLEELEKK-AEEyeklKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKldELEEELAELLKELEELGFESVEELE 591
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 484 EFLhqSKLKSFESERVQLLQ-----EETARNLTQCQLECEKYQKKLEVLTKEFYSLqassEKRITELQAQNS--EHQARL 556
Cdd:PRK03918  592 ERL--KELEPFYNEYLELKDaekelEREEKELKKLEEELDKAFEELAETEKRLEEL----RKELEELEKKYSeeEYEELR 665
                         490
                  ....*....|
gi 1164769123 557 DIYEKLEKEL 566
Cdd:PRK03918  666 EEYLELSREL 675
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
265-696 7.48e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 7.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  265 DKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERL 344
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  345 QAQLEESKKAREEMYEKYVASRDhyKTEYENKLHDELEQIRLKTNQEIDQLRNAsremyerenrsggwevqylrtgiwqe 424
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEE--RLEEAEEELAEAEAEIEELEAQIEQLKEE-------------------------- 797
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  425 pshyiiiWHKARRNLREARDNAVAEKERAvmaeKDALEKHDQLLDRYRELQlstesKVTEFLHQSKlksfesERVQLLQE 504
Cdd:TIGR02168  798 -------LKALREALDELRAELTLLNEEA----ANLRERLESLERRIAATE-----RRLEDLEEQI------EELSEDIE 855
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  505 ETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAER 584
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  585 VlfsygygaNVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSL----LNQTQQPYRYLie 660
Cdd:TIGR02168  936 V--------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAaieeYEELKERYDFL-- 1005
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1164769123  661 svrqrDSKIDSLTESIAQLEKDVSNLNKEKSALLQT 696
Cdd:TIGR02168 1006 -----TAQKEDLTEAKETLEEAIEEIDREARERFKD 1036
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
18-579 7.67e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 7.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  18 LESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVDYLTKIEELEEKLNDALH 97
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  98 QKQLLTLRLDNQLAfQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQL 177
Cdd:COG1196   331 ELEELEEELEELEE-ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 178 SIpeyvsvrfyelvnpLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELAD----TKQL 253
Cdd:COG1196   410 EA--------------LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAElleeAALL 475
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 254 IQQGDYRQENYDKVKSERDALEQEVIELR------RKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQN 327
Cdd:COG1196   476 EAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 328 MELSVRC-----AHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQE--IDQLRNASR 400
Cdd:COG1196   556 DEVAAAAieylkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtLVAARLEAA 635
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 401 EMYERENRSGGWEVQYLRTGIWQEPSHYIIIWHKARRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTES 480
Cdd:COG1196   636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 481 KVTEFLHQsklksfesERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEH----QARL 556
Cdd:COG1196   716 RLEEELEE--------EALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAI 787
                         570       580
                  ....*....|....*....|...
gi 1164769123 557 DIYEKLEKELDEIIMQTAEIENE 579
Cdd:COG1196   788 EEYEELEERYDFLSEQREDLEEA 810
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
19-284 8.07e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 8.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   19 ESEDISLETTVPTDDISSSEEREGKV--RITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVdyltKIEELEEKLNDAL 96
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQLeeRIAQLSKELTELEAEIEELEERLEEAEEELAEAEA----EIEELEAQIEQLK 795
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123   97 HQKQLLTLRLD---NQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLkafp 173
Cdd:TIGR02168  796 EELKALREALDelrAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL---- 871
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  174 EDQLSIPEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQL 253
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
                          250       260       270
                   ....*....|....*....|....*....|.
gi 1164769123  254 IQQGDyrQENYDKVKSERDALEQEVIELRRK 284
Cdd:TIGR02168  952 TLEEA--EALENKIEDDEEEARRRLKRLENK 980
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
141-721 1.77e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 1.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  141 TNLQLREKAGDVRRNLRDFElTEEQYIKLKAFP-EDQLSIPEYVSVRFYELVnplrkeiceLQVKKNILAEELSTNKNQL 219
Cdd:pfam15921  211 STMHFRSLGSAISKILRELD-TEISYLKGRIFPvEDQLEALKSESQNKIELL---------LQQHQDRIEQLISEHEVEI 280
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  220 KQLTETYEEDRKNYSEVQIRCQrlaleladtkqlIQQGDYRQENYDKVKSERDaLEQEVIELRRkhEILEASHMIQTKeR 299
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLE------------IIQEQARNQNSMYMRQLSD-LESTVSQLRS--ELREAKRMYEDK-I 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  300 SELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASR---DHYKTEYENK 376
Cdd:pfam15921  345 EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSitiDHLRRELDDR 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  377 ------LHDELEQIRLKTNQEIDQLRNASREMYERENRSGGWEVQYLRTgiwQEPSHYIIIWHKARRNLREARDNAVA-- 448
Cdd:pfam15921  425 nmevqrLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST---KEMLRKVVEELTAKKMTLESSERTVSdl 501
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  449 -----EKERAVMAEKDALEKHDQLLD-RYRELQ-LSTESKVTEFLHQS----KLKSFESERVQLLQEETARNLTQ----- 512
Cdd:pfam15921  502 taslqEKERAIEATNAEITKLRSRVDlKLQELQhLKNEGDHLRNVQTEcealKLQMAEKDKVIEILRQQIENMTQlvgqh 581
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  513 -----------CQLECEKYQKKLEVltKEFYSLQASSEKRITELQAQNSEHQ-----------ARLDIYEKLEKELDEII 570
Cdd:pfam15921  582 grtagamqvekAQLEKEINDRRLEL--QEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVKDIKQERDQLL 659
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  571 MQTAEIENE-----DEAERVLFSYGYGANVPTTAKRRLKQSVHLARRVLQlekQNSLILKDLEHRKDQVTQLSQELDRan 645
Cdd:pfam15921  660 NEVKTSRNElnslsEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE---QTRNTLKSMEGSDGHAMKVAMGMQK-- 734
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1164769123  646 sllnqtqqpyrylieSVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQIL 721
Cdd:pfam15921  735 ---------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVL 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
209-402 3.52e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 3.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 209 AEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQgdyRQENYDKVKSERDALEQEVIELRRKHEIL 288
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA---LARRIRALEQELAALEAELAELEKEIAEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 289 EASHMIQTKERSELSKEVVTLEQT----VTLLQKDK----------EYLNRQNMELSVRCAHEEDRLERLQAQLEESKKA 354
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQpplaLLLSPEDFldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1164769123 355 REEMYEKYVASRDHYKTEYE--NKLHDELEQIRLKTNQEIDQLRNASREM 402
Cdd:COG4942   176 LEALLAELEEERAALEALKAerQKLLARLEKELAELAAELAELQQEAEEL 225
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
625-740 7.96e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123 625 KDLEHRKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDL 704
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1164769123 705 EQLlnhREELAAMKQILVKMhSKHSENSLLLTKTEP 740
Cdd:COG4942   100 EAQ---KEELAELLRALYRL-GRQPPLALLLSPEDF 131
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
262-475 8.94e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.51  E-value: 8.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  262 ENYDKVKSERDAL---EQEVIELRRKHEILEashmiqtkERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSV-----R 333
Cdd:COG4913    225 EAADALVEHFDDLeraHEALEDAREQIELLE--------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLelleaE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1164769123  334 CAHEEDRLERLQAQLEESKKAREEMYEKyvasRDHYKTEYENKLHDELEQIRlktnQEIDQLRnasREMYERENRSGGWE 413
Cdd:COG4913    297 LEELRAELARLEAELERLEARLDALREE----LDELEAQIRGNGGDRLEQLE----REIERLE---RELEERERRRARLE 365
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1164769123  414 vQYLRTGIWQEPSHyIIIWHKARRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQ 475
Cdd:COG4913    366 -ALLAALGLPLPAS-AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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