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Conserved domains on  [gi|1200005324|ref|NP_001338940|]
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solute carrier family 35 member F4 isoform c [Homo sapiens]

Protein Classification

solute carrier family 35 protein( domain architecture ID 710040)

solute carrier family 35 protein is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others; belongs to the DMT (drug/metabolite transporter) superfamily

Gene Ontology:  GO:0022857|GO:0055085
PubMed:  28350329|11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RhaT super family cl34009
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 238-310 1.31e-06

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


The actual alignment was detected with superfamily member COG0697:

Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 49.07  E-value: 1.31e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1200005324 238 TATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFH-ADSIIGVAFAVGSASTSALY 310
Cdd:COG0697    91 PAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGgGGSLLGDLLALLAALSWALY 164
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 238-310 1.31e-06

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 49.07  E-value: 1.31e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1200005324 238 TATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFH-ADSIIGVAFAVGSASTSALY 310
Cdd:COG0697    91 PAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGgGGSLLGDLLALLAALSWALY 164
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 238-310 1.31e-06

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 49.07  E-value: 1.31e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1200005324 238 TATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFH-ADSIIGVAFAVGSASTSALY 310
Cdd:COG0697    91 PAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGgGGSLLGDLLALLAALSWALY 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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