|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-319 |
3.42e-116 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 344.77 E-value: 3.42e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 1 MNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP 80
Cdd:PLN02521 150 LDVVVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVAQFTCKCERHIGTQSGGMDQAISIMAQQGVAKLIDFNP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 81 LRATDVKLPSGAVFVIANSCVEMNKAATSH--FNIRVMECRLAAKLLA-KYKSLQWD---KVLRLEEVQaKLGISLEE-- 152
Cdd:PLN02521 230 VRATDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAvKLGMSAEEaisKVKTLSDVE-GLCVSFAGsh 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 153 ----MLLVTEDALHPEPYNPEEICRCLGISLEELRTQilSPNTQDVLI----FKLYQRAKHVYSEAARVLQFKKICEE-- 222
Cdd:PLN02521 309 gssdPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRAVHVYSEAKRVHAFRDTVSSsl 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 223 APENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQ- 301
Cdd:PLN02521 387 SEEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKFYKs 466
|
330 340
....*....|....*....|.
gi 1200742298 302 RSD-GSLAPEKQSL--FATKP 319
Cdd:PLN02521 467 RIEkGVIKEEDLGLyvFASKP 487
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-321 |
6.49e-60 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 196.53 E-value: 6.49e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 1 MNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLIEFS 79
Cdd:COG0153 109 FDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAEnEFVGVPCGIMDQFASALGKKGHALLLDCR 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 80 PLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNIRVMECRLAAKLLAKykslqwdKVLRleEVqaklgiSLEEmllvte 158
Cdd:COG0153 189 SLEYEYVPLPlEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR--DV------TLED------ 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 159 dalhpepynpeeicrclgisLEELRTQILSPntqdvlifKLYQRAKHVYSEAARVLQFKKICEEapeNMVQLLGELMNQS 238
Cdd:COG0153 247 --------------------LEAARARLGDE--------VLRRRARHVVTENQRVLEAVEALRA---GDLEAFGKLMNAS 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 239 HMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQRsdGSLAPEkqsLFAT 317
Cdd:COG0153 296 HASLRDDYEVSCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEK--TGLEPD---FYVV 370
|
....
gi 1200742298 318 KPGA 321
Cdd:COG0153 371 KPSD 374
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
2-323 |
3.83e-48 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 166.15 E-value: 3.83e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 2 NCLVDGNIPPSSGLSSSSALVCCAGlVTLTVLGRN--LSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFS 79
Cdd:TIGR00131 112 DIVCSGNVPTGSGLSSSAAFECAVG-AVLQNMGHLplDSKQILLRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECR 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 80 PLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNIRVMECRLAAKLLAKykslqwdkvlrleevqaKLGISLEEMLlvte 158
Cdd:TIGR00131 191 SLKATPFKFPqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAA-----------------TDKGALRDFM---- 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 159 dalhPEPYNPEEIcrclgisleelRTQILSPNTQdvlifklyQRAKHVYSEAARVLQFKKICEEapENMVQLlGELMNQS 238
Cdd:TIGR00131 249 ----NEYFARYIA-----------RLTKMLPLVE--------ERAKHVVSENLRVLKAVKAMKD--NDFKQF-GALMNES 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 239 HMSCRDMYECSCPELDQLVDICR-KFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQRSDgslAPEKQSLFAT 317
Cdd:TIGR00131 303 HASCDDDYECTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTG---LELTFYVIVS 379
|
....*.
gi 1200742298 318 KPGASE 323
Cdd:TIGR00131 380 KPGAGS 385
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
221-301 |
2.76e-08 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 50.55 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 221 EEAPENMVQLLGELMNQSHMSC--RDMYECSCPELDQLVDICRKFGAqGSRLTGAGWGGCTVSMVP-ADKLPSFLANVHK 297
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELGL-GAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 1200742298 298 AYYQ 301
Cdd:pfam08544 82 AGKK 85
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-319 |
3.42e-116 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 344.77 E-value: 3.42e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 1 MNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSP 80
Cdd:PLN02521 150 LDVVVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVAQFTCKCERHIGTQSGGMDQAISIMAQQGVAKLIDFNP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 81 LRATDVKLPSGAVFVIANSCVEMNKAATSH--FNIRVMECRLAAKLLA-KYKSLQWD---KVLRLEEVQaKLGISLEE-- 152
Cdd:PLN02521 230 VRATDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAvKLGMSAEEaisKVKTLSDVE-GLCVSFAGsh 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 153 ----MLLVTEDALHPEPYNPEEICRCLGISLEELRTQilSPNTQDVLI----FKLYQRAKHVYSEAARVLQFKKICEE-- 222
Cdd:PLN02521 309 gssdPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRAVHVYSEAKRVHAFRDTVSSsl 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 223 APENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQ- 301
Cdd:PLN02521 387 SEEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKFYKs 466
|
330 340
....*....|....*....|.
gi 1200742298 302 RSD-GSLAPEKQSL--FATKP 319
Cdd:PLN02521 467 RIEkGVIKEEDLGLyvFASKP 487
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-321 |
6.49e-60 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 196.53 E-value: 6.49e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 1 MNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLIEFS 79
Cdd:COG0153 109 FDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAEnEFVGVPCGIMDQFASALGKKGHALLLDCR 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 80 PLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNIRVMECRLAAKLLAKykslqwdKVLRleEVqaklgiSLEEmllvte 158
Cdd:COG0153 189 SLEYEYVPLPlEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR--DV------TLED------ 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 159 dalhpepynpeeicrclgisLEELRTQILSPntqdvlifKLYQRAKHVYSEAARVLQFKKICEEapeNMVQLLGELMNQS 238
Cdd:COG0153 247 --------------------LEAARARLGDE--------VLRRRARHVVTENQRVLEAVEALRA---GDLEAFGKLMNAS 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 239 HMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQRsdGSLAPEkqsLFAT 317
Cdd:COG0153 296 HASLRDDYEVSCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEK--TGLEPD---FYVV 370
|
....
gi 1200742298 318 KPGA 321
Cdd:COG0153 371 KPSD 374
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
2-323 |
3.83e-48 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 166.15 E-value: 3.83e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 2 NCLVDGNIPPSSGLSSSSALVCCAGlVTLTVLGRN--LSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFS 79
Cdd:TIGR00131 112 DIVCSGNVPTGSGLSSSAAFECAVG-AVLQNMGHLplDSKQILLRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECR 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 80 PLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNIRVMECRLAAKLLAKykslqwdkvlrleevqaKLGISLEEMLlvte 158
Cdd:TIGR00131 191 SLKATPFKFPqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAA-----------------TDKGALRDFM---- 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 159 dalhPEPYNPEEIcrclgisleelRTQILSPNTQdvlifklyQRAKHVYSEAARVLQFKKICEEapENMVQLlGELMNQS 238
Cdd:TIGR00131 249 ----NEYFARYIA-----------RLTKMLPLVE--------ERAKHVVSENLRVLKAVKAMKD--NDFKQF-GALMNES 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 239 HMSCRDMYECSCPELDQLVDICR-KFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQRSDgslAPEKQSLFAT 317
Cdd:TIGR00131 303 HASCDDDYECTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTG---LELTFYVIVS 379
|
....*.
gi 1200742298 318 KPGASE 323
Cdd:TIGR00131 380 KPGAGS 385
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-299 |
7.01e-33 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 125.36 E-value: 7.01e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 1 MNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLI--- 76
Cdd:PRK05322 113 FDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQKTEnEFIGVNSGIMDQFAIGMGKKDHAILLdcn 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 77 ----EFSPLRATDVKLpsgavfVIANScvemNKA---ATSHFNIRVMECRLAakllakykslqwdkvlrLEEVQAKLGI- 148
Cdd:PRK05322 193 tleyEYVPLDLGDYVI------VIMNT----NKRrelADSKYNERRAECEKA-----------------LEELQKKLDIk 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 149 SLEEmllVTEDALhpepynpeeicrclgislEELRTQILSPNtqdvlifkLYQRAKHVYSEAARVLQFKKICEEapeNMV 228
Cdd:PRK05322 246 SLGE---LTEEEF------------------DEYSYLIKDET--------LLKRARHAVTENQRTLKAVKALKA---GDL 293
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1200742298 229 QLLGELMNQSHMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAY 299
Cdd:PRK05322 294 EKFGRLMNASHVSLRDDYEVTGLELDTLVEAAWKQeGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAY 365
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
37-303 |
3.46e-30 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 118.10 E-value: 3.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 37 LSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNkAATSHFNIRV 115
Cdd:PRK05101 149 LSGAEIALNGQEAEnQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPMPEGVAVVIINSNVKRG-LVDSEYNTRR 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 116 MECRLAAKLLAKykslqwdKVLR---LEEVQAKlgisleemllvtEDALHPEpynpeeicrclgisleelrtqilspntq 192
Cdd:PRK05101 228 QQCETAARFFGV-------KALRdvtLEQFNAV------------AAELDPV---------------------------- 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 193 dvlifkLYQRAKHVYSEAARVLQFKKICEEapENMVqLLGELMNQSHMSCRDMYECSCPELDQLVDICR-KFGAQGS-RL 270
Cdd:PRK05101 261 ------VAKRARHVITENARTLEAASALAA--GDLK-RMGELMAESHASMRDDFEITVPQIDTLVEIVKaVIGDQGGvRM 331
|
250 260 270
....*....|....*....|....*....|...
gi 1200742298 271 TGAGWGGCTVSMVPADKLPSFLANVHKAYYQRS 303
Cdd:PRK05101 332 TGGGFGGCIVALVPEELVEAVRQAVAEQYEAKT 364
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
5-302 |
3.30e-27 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 109.32 E-value: 3.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 5 VDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSER-YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRA 83
Cdd:PRK03817 91 VSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENeFVGVPCGIMDQFAVAFGKKDHAIFLDTMTLEY 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 84 TDVKLPSGAVFVIANSCVEmNKAATSHFNIRVMECRLAAKLLAKYKSLQwdkvlrleevqaklgisleemllVTEDALHp 163
Cdd:PRK03817 171 EYVPFPEDYEILVFDTGVK-RELASSEYNERRQECEEALKILGKKSSKE-----------------------VTEEDLS- 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 164 epynpeeicrclgiSLEELrtqilspntqdvlifkLYQRAKHVYSEAARVLQFKKICEEapeNMVQLLGELMNQSHMSCR 243
Cdd:PRK03817 226 --------------KLPPL----------------LRKRAGYVLRENERVLKVRDALKE---GDIETLGELLTESHWDLA 272
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1200742298 244 DMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQR 302
Cdd:PRK03817 273 DNYEVSCEELDFFVEFALELGAYGARLTGAGFGGSAIALVDKGKFESIGEELLEEYKKR 331
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
20-298 |
6.47e-20 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 89.15 E-value: 6.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 20 ALVCCAGLVTLTVL-GRNLSKVELAEICAKSER-YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGA--VFV 95
Cdd:PRK00555 110 AALECAVLGAVGAAtGTRIDRLEQARLAQRAENeYVGAPTGLLDQLAALFGAPKTALLIDFRDLTVRPVAFDPDAagVVL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 96 IANSCVEMNKAATSHFNIRVMECRLAAKLLAkykslqwdkVLRLEEVQAKLGISLeemllvtedalhpepynpeeicrcl 175
Cdd:PRK00555 190 LLMDSRARHRHAGGEYAARRASCERAAADLG---------VSSLRAVQDRGLAAL------------------------- 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 176 gisleelrTQILSPNTqdvlifklYQRAKHVYSEAARVLQFKKICEEAPenmVQLLGELMNQSHMSCRDMYECSCPELDQ 255
Cdd:PRK00555 236 --------GAIADPID--------ARRARHVLTENQRVLDFAAALADSD---FTAAGQLLTASHASMRDDFEITTERIDL 296
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1200742298 256 LVDICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKA 298
Cdd:PRK00555 297 IADSAVRAGALGARMTGGGFGGCVIALVPADRAEDVADTVRRA 339
|
|
| PLN02865 |
PLN02865 |
galactokinase |
52-324 |
8.24e-13 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 68.67 E-value: 8.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 52 YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAV-------FVIANSCVEMNKAATSHFNIRVMECRLAAKL 124
Cdd:PLN02865 184 YLGLRNGILDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQQPggekpfkILLAFSGLRHALTNKPGYNLRVSECQEAARF 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 125 LAKYKSLqwdkvlrlEEVQAKLGisleemllvtedALHPEPYnpeeicrclgisleELRTQILSPNtqdvlifkLYQRAK 204
Cdd:PLN02865 264 LLEASGN--------DELEPLLC------------NVEPEVY--------------EAHKCKLEAV--------LARRAE 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 205 HVYSEAARVLqfkKICEEAPENMVQLLGELMNQSHMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMV 283
Cdd:PLN02865 302 HYFSENMRVI---KGVEAWASGNLEEFGKLISASGLSSIENYECGCEPLIQLYEILLKApGVYGARFSGAGFRGCCVAFV 378
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1200742298 284 PADKLPSFLANVhKAYYQRSDGSLA---PEKQSLFATKPGASER 324
Cdd:PLN02865 379 DAEMAEEAASFV-RDEYEKAQPELAsniNGDKPVLICEAGDCAR 421
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
38-302 |
9.07e-12 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 65.61 E-value: 9.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 38 SKVELAEIcAKSERYIGTEGGG-----MDQSISFLAEEG----------TAKLIEFSPLratdvkLPSGAVFVIANSCVE 102
Cdd:PTZ00290 189 SKEELIEL-AKQARRIETEFCGvnvgiMDQFISAFAEEDkfmfldckslTFESHDMTPL------LGDGACFLLIDSMIK 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 103 MNkaatshfnirvmecrLAAKLLAKYKSLQWDkvlrLEEVQAKLG--ISLEEMLLVTEDALHPEPY----NPEEIcrclg 176
Cdd:PTZ00290 262 HD---------------LLGGTAGMYNTVRSD----QEGAQKKIGkhRYRGKPFTFSDLVRNPKKYtfdgDVVAF----- 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 177 isLEELRTQiLSPNTqdvlifklYQRAKHVYSEAARVLQFKKICEEA----PENMVQLLGELMNQSHMSCRDMYECSCPE 252
Cdd:PTZ00290 318 --MESCKPL-MTPGE--------FERGTYNIMEQIRTLEFIKLNDPElplsREERFRKAGEILNAGHQGMRDLMKITTPE 386
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1200742298 253 LDQLVD-ICRKFGAQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQR 302
Cdd:PTZ00290 387 LDFIHElINEEKGVAGGRMMGGGFGGCIILLLKKNAVDRVVAHVREKFKAR 437
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
198-282 |
1.92e-11 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 64.10 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 198 KLYQRAKHVYSEAARVLQfkkiceeapENMVQLLGELMNQSHMSCRDMyECSCPELDQLVDICRKFGAQGSRLTGAGWGG 277
Cdd:PTZ00298 218 RLLENYNACVSEAKEALQ---------KGNLFRVGELMNANHDLCQKL-TVSCRELDSIVQTCRTYGALGAKMSGTGRGG 287
|
....*
gi 1200742298 278 CTVSM 282
Cdd:PTZ00298 288 LVVAL 292
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
33-278 |
2.14e-10 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 60.24 E-value: 2.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 33 LGRNLSKVELAEICAKSERYIGTEGGGMDQSISFLaeEGtakLIEF-SPLRATDVKLPSGAVFVIANSCVemnKAATSHf 111
Cdd:COG1577 114 YGVELSKEELFKLALEAEKIVHGNPSGLDTAASTY--GG---PIYYqRGDRAEPLELPKNLPLVVGDTGV---PASTKE- 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 112 nirvmecrLAAKLLAKYKSlqwdkvlrleevqaklgisleemllvtedalHPEPYNPeeicrclgisleelrtqilspnt 191
Cdd:COG1577 185 --------LVAKVRKLKER-------------------------------NPELYEA----------------------- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 192 qdvlifkLYQRAKHVYSEAARVLQfkkiceeapENMVQLLGELMNQSHmscRDMYE--CSCPELDQLVDICRKFGAQGSR 269
Cdd:COG1577 203 -------FLEEIGDLVEEAIEALE---------EGDLEALGELMNENH---GLLRAlgVSTPELDRLVEAARKAGALGAK 263
|
....*....
gi 1200742298 270 LTGAGWGGC 278
Cdd:COG1577 264 LTGAGGGGC 272
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
228-280 |
3.18e-09 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 56.92 E-value: 3.18e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1200742298 228 VQLLGELMNQSHmSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTV 280
Cdd:TIGR00549 220 VESLGELMNINQ-GLLKALGVSHPKLDQLVEIARKAGALGAKLTGAGGGGCMI 271
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
231-287 |
1.02e-08 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 55.44 E-value: 1.02e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1200742298 231 LGELMNQSHmSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTVSMVPADK 287
Cdd:PRK03926 216 LGELMNINQ-GLLDALGVSTKELSELIYAARTAGALGAKITGAGGGGCMVALAAPEK 271
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
221-301 |
2.76e-08 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 50.55 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 221 EEAPENMVQLLGELMNQSHMSC--RDMYECSCPELDQLVDICRKFGAqGSRLTGAGWGGCTVSMVP-ADKLPSFLANVHK 297
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELGL-GAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 1200742298 298 AYYQ 301
Cdd:pfam08544 82 AGKK 85
|
|
| COG2605 |
COG2605 |
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ... |
201-310 |
6.25e-06 |
|
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain] Cd Length: 328 Bit Score: 47.10 E-value: 6.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1200742298 201 QRAKHVYSEAARVLQFKKICEEApENMVQLL--------GELMNQSHMSCRDMYE-CSCPELDQLVDICRKFGAQGSRLT 271
Cdd:COG2605 205 QVKNVEDGDEATLEALHEMKELA-LEMKEALlkgdldefGELLNEGWELKKRLASgISNPAIDEIYELARKAGALGGKLL 283
|
90 100 110
....*....|....*....|....*....|....*....
gi 1200742298 272 GAGWGGCTVSMVPADKLPSFLANVHKAYYQRSDGSLAPE 310
Cdd:COG2605 284 GAGGGGFLLFYAPPERREAVREALSKAGLRVVPFSFDKE 322
|
|
| |
