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Conserved domains on  [gi|1240296508|ref|NP_001342033|]
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ERI1 exoribonuclease 2 isoform 2 [Mus musculus]

Protein Classification

DNA topoisomerase( domain architecture ID 10536289)

type I DNA topoisomerase releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-GRF pfam06839
GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding ...
 364-412 2.50e-18

GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding proteins. It seems likely that this domain is involved in nucleic acid binding. It is named GRF after three conserved residues in the centre of the alignment of the domain. This zinc finger may be related to pfam01396.


:

Pssm-ID: 462017  Cd Length: 45  Bit Score: 78.21  E-value: 2.50e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1240296508 364 PLCKCGRRSKRLIVSNNGPNHGKAFYCCPVGKYqqdrKCCGYFKWEQTL 412
Cdd:pfam06839   1 PLCPCGQRAVLLTVRKTGPNPGRQFYKCPVGRE----KQCGFFQWADEV 45
 
Name Accession Description Interval E-value
zf-GRF pfam06839
GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding ...
 364-412 2.50e-18

GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding proteins. It seems likely that this domain is involved in nucleic acid binding. It is named GRF after three conserved residues in the centre of the alignment of the domain. This zinc finger may be related to pfam01396.


Pssm-ID: 462017  Cd Length: 45  Bit Score: 78.21  E-value: 2.50e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1240296508 364 PLCKCGRRSKRLIVSNNGPNHGKAFYCCPVGKYqqdrKCCGYFKWEQTL 412
Cdd:pfam06839   1 PLCPCGQRAVLLTVRKTGPNPGRQFYKCPVGRE----KQCGFFQWADEV 45
 
Name Accession Description Interval E-value
zf-GRF pfam06839
GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding ...
 364-412 2.50e-18

GRF zinc finger; This presumed zinc binding domain is found in a variety of DNA-binding proteins. It seems likely that this domain is involved in nucleic acid binding. It is named GRF after three conserved residues in the centre of the alignment of the domain. This zinc finger may be related to pfam01396.


Pssm-ID: 462017  Cd Length: 45  Bit Score: 78.21  E-value: 2.50e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1240296508 364 PLCKCGRRSKRLIVSNNGPNHGKAFYCCPVGKYqqdrKCCGYFKWEQTL 412
Cdd:pfam06839   1 PLCPCGQRAVLLTVRKTGPNPGRQFYKCPVGRE----KQCGFFQWADEV 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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