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Conserved domains on  [gi|1243938598|ref|NP_001342505|]
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G-protein-signaling modulator 1 isoform 6 [Mus musculus]

Protein Classification

TPR and TPR_12 domain-containing protein; tetratricopeptide repeat protein( domain architecture ID 11421212)

protein containing domains TPR, TPR_12, and GoLoco; tetratricopeptide repeat (TPR) protein such as kinesin light chain, which mediates the selective binding of kinesin to its cargo

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-299 2.87e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 2.87e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  46 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 125
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 126 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 205
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 206 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 285
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1243938598 286 HLRHLVIAQELADR 299
Cdd:COG0457   207 LRKKLAILTLAALA 220
GoLoco pfam02188
GoLoco motif;
411-432 2.29e-07

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 47.03  E-value: 2.29e-07
                          10        20
                  ....*....|....*....|..
gi 1243938598 411 ECFFDLLSKFQSSRMDDQRCPL 432
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
464-484 1.58e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.58e-05
                          10        20
                  ....*....|....*....|.
gi 1243938598 464 EEFFDLIASSQSRRLDDQRAS 484
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 511-533 1.65e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


:

Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.65e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  511 GDEFFNMLIKYQSSRIDDQRCPP 533
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
546-567 1.68e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.68e-05
                          10        20
                  ....*....|....*....|..
gi 1243938598 546 EDFFSLIQRVQAKRMDEQRVDL 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
267-335 3.84e-04

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 3.84e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1243938598 267 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 335
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-299 2.87e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 2.87e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  46 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 125
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 126 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 205
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 206 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 285
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1243938598 286 HLRHLVIAQELADR 299
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR_12 pfam13424
Tetratricopeptide repeat;
184-255 4.23e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.23e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1243938598 184 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 255
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
411-432 2.29e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 47.03  E-value: 2.29e-07
                          10        20
                  ....*....|....*....|..
gi 1243938598 411 ECFFDLLSKFQSSRMDDQRCPL 432
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 410-432 1.55e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.55e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  410 EECFFDLLSKFQSSRMDDQRCPL 432
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
464-484 1.58e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.58e-05
                          10        20
                  ....*....|....*....|.
gi 1243938598 464 EEFFDLIASSQSRRLDDQRAS 484
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 511-533 1.65e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.65e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  511 GDEFFNMLIKYQSSRIDDQRCPP 533
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
546-567 1.68e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.68e-05
                          10        20
                  ....*....|....*....|..
gi 1243938598 546 EDFFSLIQRVQAKRMDEQRVDL 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
512-532 1.76e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.76e-05
                          10        20
                  ....*....|....*....|.
gi 1243938598 512 DEFFNMLIKYQSSRIDDQRCP 532
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 463-485 3.14e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.95  E-value: 3.14e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  463 TEEFFDLIASSQSRRLDDQRASV 485
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 17-375 5.68e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 46.07  E-value: 5.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  17 KAGDFKAGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEYARALQfhkhdllLARTIGDRMGEAK------- 84
Cdd:NF040586  404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  85 ----ASGNLGNTLKVLGRFDEAivccqrhLDIAQEqgdkvgearalynignvyhakgkqlSWNAAQDPghLPPDVRETLh 160
Cdd:NF040586  476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV--FGEDHPRTL- 520

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 161 rasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHIFLGR 238
Cdd:NF040586  521 -----------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRELGR 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 239 FDVAAEHYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEG----RAC-WSLG 310
Cdd:NF040586  578 YAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALELAED---TYERYRRRFGPDhpdtLAAaLSLA 654

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 311 NAYVSMGSPAQALTFAKKHLQISQEigdRNGE-----LTARMNIAHLQLALGRltsPAAAEKPDLAGYEA 375
Cdd:NF040586  655 NDLRALGDADEARELAREVLDRYRR---VLGEdhpftLACRNNLAVLLRALGD---PEEARELAEAALEG 718
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 545-567 9.78e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 39.41  E-value: 9.78e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  545 DEDFFSLIQRVQAKRMDEQRVDL 567
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
267-335 3.84e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 3.84e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1243938598 267 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 335
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 83-115 7.86e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 7.86e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1243938598   83 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 115
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-299 2.87e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 2.87e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  46 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 125
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 126 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 205
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 206 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 285
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1243938598 286 HLRHLVIAQELADR 299
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-366 3.67e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 3.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  82 EAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEqgdkvgEARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHR 161
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR--------------------YEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 162 ASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDV 241
Cdd:COG0457    61 ALADYEQALEL------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 242 AAEHYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLviAQELADRVGEGRACWSLGNAYVSMGSPAQ 321
Cdd:COG0457   129 AIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEKLE--AAALAALLAAALGEAALALAAAEVLLALL 200

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1243938598 322 ALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAE 366
Cdd:COG0457   201 LALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
122-405 6.16e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 6.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 122 EARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLVKELGDraaqgrAYGNLGNTHYLLGNFTE 201
Cdd:COG0457     7 DAEAYNNLGLAYRRLGR--------------------YEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 202 ATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQDYER 281
Cdd:COG0457    61 ALADYEQALELDPDDAE------ALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 282 AAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPAQALTFAKKHLQisQEIGDRNGELTARMNIAHLQLALGRLTS 361
Cdd:COG0457   129 AIEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEA--AALAALLAAALGEAALALAAAEVLLALL 200

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1243938598 362 PAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLDRGIPRA 405
Cdd:COG0457   201 LALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 10-331 1.47e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 1.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  10 LEGERLCKAGDFKAGVAFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLKEYARALQFHKHdlLLARTiGDRmgeAKASGNL 89
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQK--LLERD-PDR---AEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  90 GNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERn 169
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEKLLELDPDD------AEALRLLAEIYEQEGD--------------------WEKAIEVLER- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 170 lsLVKELGDRAaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFgdkaaeRRAYSNLGNAHIFLGRFDVAAEHYKKT 249
Cdd:COG2956   136 --LLKLGPENA---HAYCELAELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 250 LQLSRQLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADRVgegracwSLGNAYVSMGSPAQALTFAKKH 329
Cdd:COG2956   205 LEQDPDY------LPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-------ALADLLERKEGLEAALALLERQ 271


                  ..
gi 1243938598 330 LQ 331
Cdd:COG2956   272 LR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 8-252 3.47e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.25  E-value: 3.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598   8 LALEGERLCKAGDFKAGVAFFEAAVQvGTEDLKTLSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTIGDRMGEAKASG 87
Cdd:COG3914     4 AALLALAALAAAALLAAAAAAELALA-AELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  88 NLGNTLKVLGRFDEAIVCCQRHLDIAqeqgdkVGEARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYE 167
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALN------PDNAEALFNLGNLLLALGR--------------------LEEALAALR 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 168 RNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYK 247
Cdd:COG3914   137 RALAL------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQDLGRLEEAIAAYR 204


                  ....*
gi 1243938598 248 KTLQL 252
Cdd:COG3914   205 RALEL 209
TPR_12 pfam13424
Tetratricopeptide repeat;
184-255 4.23e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.23e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1243938598 184 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 255
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 161-359 6.81e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 6.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 161 RASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFD 240
Cdd:COG3914    16 ALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 241 VAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPA 320
Cdd:COG3914    96 EALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGRLE 163

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1243938598 321 QALTFAKKHLQIsqeigdRNGELTARMNIAHLQLALGRL 359
Cdd:COG3914   164 EAIAALRRALEL------DPDNAEALNNLGNALQDLGRL 196
COG3899 COG3899
Predicted ATPase [General function prediction only];
99-408 1.25e-08

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 58.33  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598   99 FDEAIVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKqlswnaaqdpghlPPDVRETLHRASEFYERNLSLVKELGD 178
Cdd:COG3899    721 YAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGR-------------FEEAEALLERALAARALAALAALRHGN 787

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  179 RAAQGRAYGNLGntHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRD 258
Cdd:COG3899    788 PPASARAYANLG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGD 865

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  259 QAVEAQACYSLGNTyTLLQDYERAAEYHLRHLVIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGD 338
Cdd:COG3899    866 AALALLALAAAAAA-AAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAA 944

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  339 RNGELTARMNIAHLQLALGRLTSPAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLDRGIPRAPSS 408
Cdd:COG3899    945 LAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAA 1014
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 88-359 2.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 2.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  88 NLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYE 167
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDR------AEALLELAQDYLKAGL--------------------LDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 168 RnlsLVKELGDRAaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEfgdkaaERRAYSNLGNAHIFLGRFDVAAEHYK 247
Cdd:COG2956   101 K---LLELDPDDA---EALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 248 KTLQLSRQlrdqAVEAQacYSLGNTYTLLQDYERAAEYHLRhlVIAQELADRVGEGRacwsLGNAYVSMGSPAQALTFAK 327
Cdd:COG2956   169 KALKLDPD----CARAL--LLLAELYLEQGDYEEAIAALER--ALEQDPDYLPALPR----LAELYEKLGDPEEALELLR 236

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1243938598 328 KHLQisqeigdRNGELTARMNIAHLQLALGRL 359
Cdd:COG2956   237 KALE-------LDPSDDLLLALADLLERKEGL 261
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 37-262 2.62e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 2.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  37 EDLKTLSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTigdrmgEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQ 116
Cdd:COG3914    72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 117 gdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLL 196
Cdd:COG3914   146 ------AEAYLNLGEALRRLGR--------------------LEEAIAALRRALEL------DPDNAEALNNLGNALQDL 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1243938598 197 GNFTEATTFHKERLAIAKEFgdkaaeRRAYSNLgnahIFLGRFDVAAEHYKKTLQLSRQLRDQAVE 262
Cdd:COG3914   194 GRLEEAIAAYRRALELDPDN------ADAHSNL----LFALRQACDWEVYDRFEELLAALARGPSE 249
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 180-335 1.73e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.58  E-value: 1.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 180 AAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdq 259
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE------AFALLGEILLQLGDLDEAIVLLHEALELDPD---- 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1243938598 260 avEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPAQALTFAKKHLQISQE 335
Cdd:COG4783    71 --EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRPDEAIAALEKALELDPD 138
GoLoco pfam02188
GoLoco motif;
411-432 2.29e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 47.03  E-value: 2.29e-07
                          10        20
                  ....*....|....*....|..
gi 1243938598 411 ECFFDLLSKFQSSRMDDQRCPL 432
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
COG3899 COG3899
Predicted ATPase [General function prediction only];
151-405 4.06e-06

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 49.86  E-value: 4.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  151 LPPDVRETLH-RASEFYERNLSLVKEL------------GDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG 217
Cdd:COG3899    660 LPPEERRALHrRIARALEARGPEPLEErlfelahhlnraGERDRAARLLLRAARRALARGAYAEALRYLERALELLPPDP 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  218 DKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYT-----LLQDYERAAEYHLRHLVI 292
Cdd:COG3899    740 EEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYAnlgllLLGDYEEAYEFGELALAL 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  293 AQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAEKPDLAG 372
Cdd:COG3899    820 AERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAA 899

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1243938598  373 YEAQGARPKRTQRLSAETWDLLRLPLDRGIPRA 405
Cdd:COG3899    900 AAAALAAAAAAAALAAAELARLAAAAAAAAALA 932
TPR_12 pfam13424
Tetratricopeptide repeat;
224-295 4.67e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 44.69  E-value: 4.67e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1243938598 224 RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLR--DQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQE 295
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
12-138 5.31e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.08  E-value: 5.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  12 GERLCKAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQfhkhdlLLARTIGDRMGEAKASGNLGN 91
Cdd:COG0457    49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALE------DYDKALELDPDDAEALYNLGL 118

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1243938598  92 TLKVLGRFDEAIVCCQRHLDIaqeqgdKVGEARALYNIGNVYHAKGK 138
Cdd:COG0457   119 ALLELGRYDEAIEAYERALEL------DPDDADALYNLGIALEKLGR 159
TPR_12 pfam13424
Tetratricopeptide repeat;
83-139 1.29e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 1.29e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1243938598  83 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQ--GDKVGEARALYNIGNVYHAKGKQ 139
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRY 61
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 410-432 1.55e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.55e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  410 EECFFDLLSKFQSSRMDDQRCPL 432
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
464-484 1.58e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.58e-05
                          10        20
                  ....*....|....*....|.
gi 1243938598 464 EEFFDLIASSQSRRLDDQRAS 484
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 511-533 1.65e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.65e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  511 GDEFFNMLIKYQSSRIDDQRCPP 533
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
546-567 1.68e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.68e-05
                          10        20
                  ....*....|....*....|..
gi 1243938598 546 EDFFSLIQRVQAKRMDEQRVDL 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
512-532 1.76e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 41.64  E-value: 1.76e-05
                          10        20
                  ....*....|....*....|.
gi 1243938598 512 DEFFNMLIKYQSSRIDDQRCP 532
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 463-485 3.14e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.95  E-value: 3.14e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  463 TEEFFDLIASSQSRRLDDQRASV 485
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
COG3899 COG3899
Predicted ATPase [General function prediction only];
6-405 4.48e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 46.78  E-value: 4.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598    6 LELALE-GERLCKAGDFKAGVAFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTIG 77
Cdd:COG3899    745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598   78 DRMGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQGDKVGEARALYniGNVYHAKGKQLSWNAAQDPGHLPPDVRE 157
Cdd:COG3899    825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALA--AAAAAAAAAAALAAAAAAAARLLAAAAA 902

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  158 TLHRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLG 237
Cdd:COG3899    903 ALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAA 982

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  238 RFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADRVGEGRACWSLGNAYVSMG 317
Cdd:COG3899    983 AAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAAL 1062

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  318 SPAQALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLP 397
Cdd:COG3899   1063 AAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAAL 1142


                   ....*...
gi 1243938598  398 LDRGIPRA 405
Cdd:COG3899   1143 ALALAALL 1150
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 17-375 5.68e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 46.07  E-value: 5.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  17 KAGDFKAGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEYARALQfhkhdllLARTIGDRMGEAK------- 84
Cdd:NF040586  404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  85 ----ASGNLGNTLKVLGRFDEAivccqrhLDIAQEqgdkvgearalynignvyhakgkqlSWNAAQDPghLPPDVRETLh 160
Cdd:NF040586  476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV--FGEDHPRTL- 520

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 161 rasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHIFLGR 238
Cdd:NF040586  521 -----------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRELGR 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 239 FDVAAEHYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEG----RAC-WSLG 310
Cdd:NF040586  578 YAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALELAED---TYERYRRRFGPDhpdtLAAaLSLA 654

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 311 NAYVSMGSPAQALTFAKKHLQISQEigdRNGE-----LTARMNIAHLQLALGRltsPAAAEKPDLAGYEA 375
Cdd:NF040586  655 NDLRALGDADEARELAREVLDRYRR---VLGEdhpftLACRNNLAVLLRALGD---PEEARELAEAALEG 718
TPR_12 pfam13424
Tetratricopeptide repeat;
123-215 6.08e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 6.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 123 ARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLVKEL--GDRAAQGRAYGNLGNTHYLLGNFT 200
Cdd:pfam13424   3 ATALNNLAAVLRRLGR--------------------YDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYE 62

                          90
                  ....*....|....*
gi 1243938598 201 EATTFHKERLAIAKE 215
Cdd:pfam13424  63 EALELLERALALAEK 77
TPR_12 pfam13424
Tetratricopeptide repeat;
42-115 8.33e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 8.33e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1243938598  42 LSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTI--GDRMGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 115
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 545-567 9.78e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 39.41  E-value: 9.78e-05
                           10        20
                   ....*....|....*....|...
gi 1243938598  545 DEDFFSLIQRVQAKRMDEQRVDL 567
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 220-359 1.44e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 220 AAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYhlrhlvIAQELADR 299
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPD------NPEAFALLGEILLQLGDLDEAIVL------LHEALELD 68

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 300 VGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGDrngeltARMNIAHLQLALGRL 359
Cdd:COG4783    69 PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRP 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 7-138 2.25e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598   7 ELALEGERLCKAGDFKAGVAFFEAAVQVGTEDLktlsAIYSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKAS 86
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1243938598  87 GNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGK 138
Cdd:COG4783    76 LNLGLALLKAGDYDEALALLEKALKLDPEH------PEAYLRLARAYRALGR 121
TPR_7 pfam13176
Tetratricopeptide repeat;
265-299 2.62e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 2.62e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1243938598 265 ACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADR 299
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 176-293 3.05e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 3.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 176 LGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 255
Cdd:COG5010    47 RDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------LYYNLALLYSRSGDKDEAKEYYEKALALSPD 120

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1243938598 256 lrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIA 293
Cdd:COG5010   121 ------NPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
TPR_12 pfam13424
Tetratricopeptide repeat;
267-335 3.84e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 3.84e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1243938598 267 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 335
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_1 pfam00515
Tetratricopeptide repeat;
83-115 5.73e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 5.73e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1243938598  83 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 115
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
122-305 7.38e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 7.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 122 EARALYNIGNVYHAKGKqlsWNAAqdpghlppdvRETLHRAsefyernLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTE 201
Cdd:COG4785    72 LAQLYYERGVAYDSLGD---YDLA----------IADFDQA-------LEL------DPDLAEAYNNRGLAYLLLGDYDA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 202 ATtfhkERLAIAKEFGDKAAErrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYslgntytLLQDYER 281
Cdd:COG4785   126 AL----EDFDRALELDPDYAY--AYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAE-------RKLDPEK 192

                         170       180
                  ....*....|....*....|....
gi 1243938598 282 AAEYHLRHLVIAQELADRVGEGRA 305
Cdd:COG4785   193 ALALLLEDWATAYLLQGDTEEARE 216
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 83-115 7.86e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 7.86e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1243938598   83 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 115
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
224-252 1.44e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.24  E-value: 1.44e-03
                          10        20
                  ....*....|....*....|....*....
gi 1243938598 224 RAYSNLGNAHIFLGRFDVAAEHYKKTLQL 252
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
161-258 1.54e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 161 RASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKerlAIAKEFGDKaaerRAYSNLGNAHIFLGRFD 240
Cdd:COG3063    10 EAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEAIALEK---ALKLDPNNA----EALLNLAELLLELGDYD 76

                          90
                  ....*....|....*...
gi 1243938598 241 VAAEHYKKTLQLSRQLRD 258
Cdd:COG3063    77 EALAYLERALELDPSALR 94
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 224-333 1.67e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 224 RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQEladrvgEG 303
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGDTEEAEELLERALALDPD------NP 85

                          90       100       110
                  ....*....|....*....|....*....|
gi 1243938598 304 RACWSLGNAYVSMGSPAQALTFAKKHLQIS 333
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
12-182 2.47e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  12 GERLCKAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGN 91
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDD----AEALYNLGLALLELGRYDEAIEAYERALELDP------DDADALYNLGI 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  92 TLKVLGRFDEAIVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAAQDPGHLPPDVRETLHRASEFYERNLS 171
Cdd:COG0457   153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232

                         170
                  ....*....|.
gi 1243938598 172 LVKELGDRAAQ 182
Cdd:COG0457   233 LRLAALALYQY 243
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 172-285 2.94e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 172 LVKELGDRAAQ----GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYK 247
Cdd:COG4235     2 AIARLRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD------ALLDLAEALLAAGDTEEAEELLE 75

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1243938598 248 KTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEY 285
Cdd:COG4235    76 RALALDPD------NPEALYLLGLAAFQQGDYAEAIAA 107
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
232-335 3.18e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 232 AHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHlRHLVIAQELADrvgegrACWSLGN 311
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAE------ALLNLAE 67

                          90       100
                  ....*....|....*....|....
gi 1243938598 312 AYVSMGSPAQALTFAKKHLQISQE 335
Cdd:COG3063    68 LLLELGDYDEALAYLERALELDPS 91
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 197-359 3.65e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.99  E-value: 3.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 197 GNFTEATTFHKERLAIAKEfgDKAAER-RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTl 275
Cdd:pfam17874  15 GDAERALELAEQALALLPE--DDLLARgLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTLWALLQQGEILR- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 276 LQDYERAAEYHLRHlviAQELADRVGE------GRACWSLGNAYVSMGSPAQALTFAKKHLQISQEiGDRNGELTARMNI 349
Cdd:pfam17874  92 AQGRLHQALETYQQ---ALQLARDHGLqhlplhGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQ-WEPDAAVDAYVLL 167

                         170
                  ....*....|
gi 1243938598 350 AHLQLALGRL 359
Cdd:pfam17874 168 ARIALAQGEL 177
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-285 4.98e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 4.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 193 HYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDvAAEHYKKTLQLSRQlrdqavEAQACYSLGNT 272
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNAD------ALNNLGLLLLEQGRYD-EAIALEKALKLDPN------NAEALLNLAEL 68

                          90
                  ....*....|...
gi 1243938598 273 YTLLQDYERAAEY 285
Cdd:COG3063    69 LLELGDYDEALAY 81
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 232-328 6.02e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 6.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 232 AHIFLGRFDVAAEHYKktlQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEGRACWSLGN 311
Cdd:COG1729     2 ALLKAGDYDEAIAAFK---AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                          90
                  ....*....|....*..
gi 1243938598 312 AYVSMGSPAQALTFAKK 328
Cdd:COG1729    76 SYLELGDYDKARATLEE 92
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 171-251 7.74e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.51  E-value: 7.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598 171 SLVKELGDRAAQGRAYGNLGNTHYLLGNFTEA-TTFhkerLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKT 249
Cdd:COG1729    18 AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAaEAF----EKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEEL 93


                  ..
gi 1243938598 250 LQ 251
Cdd:COG1729    94 IK 95
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
17-115 8.44e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 35.92  E-value: 8.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243938598  17 KAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQFHKhdlllARTIGDRMGEAKAsgNLGNTLKVL 96
Cdd:COG3063     4 KLGDLEEAEEYYEKALELDPDN----ADALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAEALL--NLAELLLEL 72

                          90
                  ....*....|....*....
gi 1243938598  97 GRFDEAIVCCQRHLDIAQE 115
Cdd:COG3063    73 GDYDEALAYLERALELDPS 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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