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Conserved domains on  [gi|1251770303|ref|NP_001343392|]
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sushi domain-containing protein 4 isoform 2 precursor [Mus musculus]

Protein Classification

CCP domain-containing protein( domain architecture ID 13332521)

CCP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 57-238 9.43e-14

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 9.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  57 CADPGVPENGfRTPSGGVFFESSVTrFHCQDGFRLKGSTKRLCMKHFNGTLGWVPsDKPVCIQEDCRIP-QIEDAEIR-- 133
Cdd:PHA02927   86 CPSPRDIDNG-QLDIGGVDFGSSIT-YSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPpSISNGRHNgy 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 134 NKTYRHGEKLVIDCHEGFKIrypdLYNLVSLCrDDGTWDNLPICQ--GCLRPlASSNGYVNiSEFQTSFPVGTVIAYRCF 211
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                         170       180
                  ....*....|....*....|....*..
gi 1251770303 212 PGFKLEGSENLECLHNLIWSSSPPRCL 238
Cdd:PHA02927  236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 245-299 4.52e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 4.52e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1251770303  245 CPLPPMVSHGDFICHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 299
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 57-238 9.43e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 9.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  57 CADPGVPENGfRTPSGGVFFESSVTrFHCQDGFRLKGSTKRLCMKHFNGTLGWVPsDKPVCIQEDCRIP-QIEDAEIR-- 133
Cdd:PHA02927   86 CPSPRDIDNG-QLDIGGVDFGSSIT-YSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPpSISNGRHNgy 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 134 NKTYRHGEKLVIDCHEGFKIrypdLYNLVSLCrDDGTWDNLPICQ--GCLRPlASSNGYVNiSEFQTSFPVGTVIAYRCF 211
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                         170       180
                  ....*....|....*....|....*..
gi 1251770303 212 PGFKLEGSENLECLHNLIWSSSPPRCL 238
Cdd:PHA02927  236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 1.29e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.29e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1251770303 180 CLRPLASSNGYVNISefQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.40e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.68  E-value: 1.40e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1251770303  180 CLRPLASSNGYVNISefQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 245-299 4.52e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 4.52e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1251770303  245 CPLPPMVSHGDFICHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 299
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 245-296 9.71e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.61  E-value: 9.71e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1251770303 245 CPLPPMVSHGDFICHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 296
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 1.45e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.45e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1251770303 190 YVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
245-296 1.10e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.10e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1251770303 245 CPLPPMVSHGDFIChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 296
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 57-238 9.43e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 9.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  57 CADPGVPENGfRTPSGGVFFESSVTrFHCQDGFRLKGSTKRLCMKHFNGTLGWVPsDKPVCIQEDCRIP-QIEDAEIR-- 133
Cdd:PHA02927   86 CPSPRDIDNG-QLDIGGVDFGSSIT-YSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPpSISNGRHNgy 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 134 NKTYRHGEKLVIDCHEGFKIrypdLYNLVSLCrDDGTWDNLPICQ--GCLRPlASSNGYVNiSEFQTSFPVGTVIAYRCF 211
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                         170       180
                  ....*....|....*....|....*..
gi 1251770303 212 PGFKLEGSENLECLHNLIWSSSPPRCL 238
Cdd:PHA02927  236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
 30-238 4.20e-12

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 67.00  E-value: 4.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  30 LAVILWFQLALCFgpaqlTGGFDDLnVCADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHFNGTLgW 109
Cdd:PHA02639    1 MKIILYLFIGVCY-----VHGVKSI-YCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 110 vPSDKPVCIQEDCR-IPQIEDAEIRNK--TYRHGEKLVIDCHEGFKIRYPDLYNLVSLCRDDGTWD-NLPICQ--GCLRP 183
Cdd:PHA02639   74 -SNKAPFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRFP 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1251770303 184 lASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRCL 238
Cdd:PHA02639  153 -ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 180-237 1.29e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.29e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1251770303 180 CLRPLASSNGYVNISefQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:cd00033     1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 180-237 1.40e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.68  E-value: 1.40e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1251770303  180 CLRPLASSNGYVNISefQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 134-296 4.87e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 57.36  E-value: 4.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 134 NKTYRHGEKLVIDCHEGFkiRYPDLYNLVSLCRDDG-TWDNLPICQGCLRPLASSNGYVNISefqtSFPVGTVIAYRCFP 212
Cdd:PHA02927   41 NANYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGwTLFNQCIKRRCPSPRDIDNGQLDIG----GVDFGSSITYSCNS 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 213 GFKLEGSENLEC----LHNLIWSSSPPRClalEAQVCPLPPMVSHGDficHPRPCERYNHGTVVEFYCDPGYSLTSDYKy 288
Cdd:PHA02927  115 GYQLIGESKSYCelgsTGSMVWNPEAPIC---ESVKCQSPPSISNGR---HNGYEDFYTDGSVVTYSCNSGYSLIGNSG- 187


                  ....*...
gi 1251770303 289 ITCQYGEW 296
Cdd:PHA02927  188 VLCSGGEW 195
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 245-299 4.52e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 4.52e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1251770303  245 CPLPPMVSHGDFICHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 299
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
PHA02831 PHA02831
EEV host range protein; Provisional
 104-238 5.74e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 53.84  E-value: 5.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 104 NGTlgWvpSDKPVCI-QEDCRIP-QIEDAEIRNKT--YRHGEKLVIDCHEGFKIRYPDLYNLVSLCRDdGTW--DNlPIC 177
Cdd:PHA02831   63 NGS--W--STKNMCIgKRNCKDPvTILNGYIKNKKdqYSFGDSVTYACKVNKLEKYSIVGNETVKCIN-KQWvpKY-PVC 136

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1251770303 178 Q--GCLRPlASSNGYVNIseFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRCL 238
Cdd:PHA02831  137 KliRCKYP-ALQNGFLNV--FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 245-296 9.71e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.61  E-value: 9.71e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1251770303 245 CPLPPMVSHGDFICHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 296
Cdd:cd00033     1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
190-237 1.45e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.45e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1251770303 190 YVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:pfam00084   9 NGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 57-118 3.79e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.07  E-value: 3.79e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1251770303  57 CADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHfngtLGWVPSdKPVCI 118
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN----GGWSPP-PPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 57-117 1.72e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.21  E-value: 1.72e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1251770303   57 CADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKhfNGTlgWVPSdKPVC 117
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE--NGT--WSPP-PPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 134-306 2.60e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 48.84  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 134 NKTYRHGEKLVIDCHEGFkirypdlyNLVSLCRDDGTWDNLPICQG---CLRPLASSNGYVNISEFQTSFpvGTVIAYRC 210
Cdd:PHA02831   37 NKVYEENENLEYKCNNNF--------DKVFVTCNNGSWSTKNMCIGkrnCKDPVTILNGYIKNKKDQYSF--GDSVTYAC 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 211 ----FPGFKLEGSENLECLhNLIWSSSPPRCLALEAQVcplpPMVSHGDFICHPRpceRYNHGTVVEFYCDPGY----SL 282
Cdd:PHA02831  107 kvnkLEKYSIVGNETVKCI-NKQWVPKYPVCKLIRCKY----PALQNGFLNVFEK---KFYYGDIVNFKCKKGFillgSS 178

                         170       180
                  ....*....|....*....|....*
gi 1251770303 283 TSdykyiTCQYGE-WFPSYQvYCIK 306
Cdd:PHA02831  179 VS-----TCDINSiWYPGIP-KCVK 197
PHA02817 PHA02817
EEV Host range protein; Provisional
 117-237 5.64e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 47.63  E-value: 5.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 117 CIQEDCRIP-QIEDAEIRNK--TYRHGEKLVIDCHEGFK-IRYPDLYNLVSLCRDDGTWD-NLPICQ--GCLRPlASSNG 189
Cdd:PHA02817   19 CDLNKCCYPpSIKNGYIYNKktEYNIGSNVTFFCGNNTRgVRYTLVGEKNIICEKDGKWNkEFPVCKiiRCRFP-ALQNG 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1251770303 190 YVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRC 237
Cdd:PHA02817   98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
245-296 1.10e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.10e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1251770303 245 CPLPPMVSHGDFIChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 296
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 92-247 1.24e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.00  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  92 KGSTKRLCMKHFNGTLGWvpSDKPVCIQEDCRIPQIEDAEIR--NKTYRHGEKLVIDCHEGFKIRYPDLYNLVSlcrddG 169
Cdd:PHA02954  102 KDETKYFRCEEKNGNTSW--NDTVTCPNAECQPLQLEHGSCQpvKEKYSFGEHITINCDVGYEVIGASYISCTA-----N 174

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1251770303 170 TWDNLPICQGCLRPLASSNGYVNISefqtSFPVGTVIAYRCFPGFKLEGSENLECLHNLiWSSSPPRCLALEAQVCPL 247
Cdd:PHA02954  175 SWNVIPSCQQKCDIPSLSNGLISGS----TFSIGGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICVRSNEEFDPV 247
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 54-298 1.92e-05

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 46.18  E-value: 1.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303  54 LNVCADPGVP-----ENGFRTPSGGVFFESSVTRFHCQDGFRLK--GSTKRLCmkhfNGTlGWVPSDKpvCIQEDCRIPQ 126
Cdd:PHA02927   18 LSCCTIPSRPinmkfKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKC----TGT-GWTLFNQ--CIKRRCPSPR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 127 -IEDAEIRNKTYRHGEKLVIDCHEGFKIrypdLYNLVSLCRDDGT----WD-NLPICQG--CLRPLASSNGYVNisEFQT 198
Cdd:PHA02927   91 dIDNGQLDIGGVDFGSSITYSCNSGYQL----IGESKSYCELGSTgsmvWNpEAPICESvkCQSPPSISNGRHN--GYED 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 199 SFPVGTVIAYRCFPGFKLEGSENLECLHNLiWSSsPPRCLALEaqvCPlPPMVSHGDFICHPRpcERYNHGTVVEFYCDP 278
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-WSD-PPTCQIVK---CP-HPTISNGYLSSGFK--RSYSYNDNVDFKCKY 236

                         250       260
                  ....*....|....*....|.
gi 1251770303 279 GYSLTSDYKYiTCQYGE-WFP 298
Cdd:PHA02927  237 GYKLSGSSSS-TCSPGNtWQP 256
PHA02639 PHA02639
EEV host range protein; Provisional
 180-298 2.35e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 46.20  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1251770303 180 CLRPLASSNGYvnISEFQTSFPVGTVIAYRCFPGFKLEGSENLECL---HNLIWSSSPPRCLALEaqvCPLPPMVSHGDf 256
Cdd:PHA02639   22 CDKPDDISNGF--ITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdkNNAIWSNKAPFCMLKE---CNDPPSIINGK- 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1251770303 257 ICHPRpcERYNHGTVVEFYCDP----GYSLTSDYKYITCQYGEWFP 298
Cdd:PHA02639   96 IYNKR--EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKP 139
Sushi pfam00084
Sushi repeat (SCR repeat);
57-117 1.18e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 39.79  E-value: 1.18e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1251770303  57 CADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHFNgtlgWVPSDkPVC 117
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT----WSPPF-PEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 125-177 3.95e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.58  E-value: 3.95e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1251770303  125 PQIEDAEIR--NKTYRHGEKLVIDCHEGFKIRYPDlynlVSLCRDDGTWDN-LPIC 177
Cdd:smart00032   5 PDIENGTVTssSGTYSYGDTVTYSCDPGYTLIGSS----TITCLENGTWSPpPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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