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Conserved domains on  [gi|1383482556|ref|NP_001349655|]
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zinc finger protein 62 isoform 1 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
437-850 4.93e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 437 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 514
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 515 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 587
Cdd:COG5048   112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 588 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 664
Cdd:COG5048   192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 665 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 737
Cdd:COG5048   263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 738 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 806
Cdd:COG5048   343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1383482556 807 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 850
Cdd:COG5048   423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 379-458 5.56e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 379 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 455
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                  ...
gi 1383482556 456 VHR 458
Cdd:COG5189   416 YHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
127-542 2.37e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 127 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 202
Cdd:COG5048    30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 203 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 280
Cdd:COG5048   110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 281 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 360
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 361 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 427
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 428 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 496
Cdd:COG5048   341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1383482556 497 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 542
Cdd:COG5048   421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
437-850 4.93e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 437 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 514
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 515 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 587
Cdd:COG5048   112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 588 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 664
Cdd:COG5048   192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 665 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 737
Cdd:COG5048   263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 738 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 806
Cdd:COG5048   343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1383482556 807 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 850
Cdd:COG5048   423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 379-458 5.56e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 379 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 455
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                  ...
gi 1383482556 456 VHR 458
Cdd:COG5189   416 YHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
127-542 2.37e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 127 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 202
Cdd:COG5048    30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 203 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 280
Cdd:COG5048   110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 281 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 360
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 361 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 427
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 428 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 496
Cdd:COG5048   341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1383482556 497 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 542
Cdd:COG5048   421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 493-541 3.75e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.75e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1383482556 493 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 541
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
286-310 3.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.86e-04
                          10        20
                  ....*....|....*....|....*
gi 1383482556 286 LRVHKRIHTGEKPYECDECGKAFIT 310
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
370-394 1.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.44e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 370 LIVHKRIHTGEKPYKCDICGKAFSY 394
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
817-840 1.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.51e-03
                          10        20
                  ....*....|....*....|....
gi 1383482556 817 LDQHKRIHTGKKPYRCNDCGKAFN 840
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 353-401 2.27e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 2.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1383482556 353 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDICGKAFSYSSGLAVH 401
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
437-850 4.93e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 437 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 514
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 515 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 587
Cdd:COG5048   112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 588 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 664
Cdd:COG5048   192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 665 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 737
Cdd:COG5048   263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 738 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 806
Cdd:COG5048   343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 1383482556 807 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 850
Cdd:COG5048   423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
324-766 4.75e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.79  E-value: 4.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 324 DKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYEC--DECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKafSYSSGLAVH 401
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLP--LSNSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 402 KSIHpgkkaheckdCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTgekpyKCDVCGKAYISRSS 481
Cdd:COG5048   109 SLSS----------SSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSV-----NTPQSNSLHPPLPA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 482 LKNHKGIHMGEKPYKCSycEKSFNYSSALEQHKRIHTREKPFGCDECGKaFRNNSGLKVHKRIHTGERPYKCEecgkayi 561
Cdd:COG5048   174 NSLSKDPSSNLSLLISS--NVSTSIPSSSENSPLSSSYSIPSSSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ------- 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 562 slssliNHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGE-------KPYKCDVCEKSFNYTSLLSQHKR--VHTRE 632
Cdd:COG5048   244 ------SPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGE 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 633 --KPFECD--RCEKVFRNNSSLKVHKRIHTGEKPYECDIC--------GKAYISHSSLINHKSTHPGKTSYTCDECGKAF 700
Cdd:COG5048   318 slKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfspLLNNEPPQSLQQYKDLKNDKKSETLSNSCIRN 397

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1383482556 701 FSSR-TLISHKRVHLGEKP--FKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHK 766
Cdd:COG5048   398 FKRDsNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 379-458 5.56e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 379 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 455
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                  ...
gi 1383482556 456 VHR 458
Cdd:COG5189   416 YHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 458-542 2.02e-08

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 57.42  E-value: 2.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 458 RRLHT-GEKPYKCDV--CGKAYISRSSLKNHKgihmgekpyKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRN 534
Cdd:COG5189   340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410


                  ....*...
gi 1383482556 535 NSGLKVHK 542
Cdd:COG5189   411 LNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
269-655 9.13e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 9.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 269 KPYECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSI------------------HFGDKPYKCD 330
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLrthhnnpsdlnskslplsNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 331 ECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEK-------PYKCDICGKAFSYSSGLAVHKS 403
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 404 IHPGKKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLK 483
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 484 NHKGIHMGE-------KPYKCSYCEKSFNYSSALEQHKR--IHTRE--KPFGCDE--CGKAFRNNSGLKVHKRIHTGERP 550
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 551 YKC--EECGKAYISLSSLINHKSVHP-----GEKPFKCD--ECEKAFITYRTLLNHKKIHLGEKP--YKCDVCEKSFNYT 619
Cdd:COG5048   352 AKEklLNSSSKFSPLLNNEPPQSLQQykdlkNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1383482556 620 SLLSQHKRVHTREKPFECdRCEKVFRNNSSLKVHKR 655
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
185-590 1.03e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 1.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 185 KPYKCDECGKAYMSYSSLINHKSTHSGEKNCKC--DECGKSFNYSSVLDQHKRIHTGEKPYECgeCGKAFRNSSGLRVHK 262
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLN--SKSLPLSNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 263 RIHTGEKP-YECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHfgDKPYKCdECEKSFNYSSL 341
Cdd:COG5048   110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHP--PLPANS-LSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 342 LIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTgEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKDCGKSFS 421
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 422 YNSLLLQHKTIHTGER-------PYVCDVCGKTFRNNSGLKVHRR--LHTGE--KPYKCDV--CGKAYISRSSLKNHKGI 488
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 489 HMGEKPYKCSYCEKSFNYSSAL-------EQHKRIHTREKPFGCD--ECGKAFRNNSGLKVHKRIHTGERP--YKCEECG 557
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLnneppqsLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420       430
                  ....*....|....*....|....*....|...
gi 1383482556 558 KAYISLSSLINHKSVHPGEKPFKCDECEKAFIT 590
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRD 458
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
127-542 2.37e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 127 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 202
Cdd:COG5048    30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 203 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 280
Cdd:COG5048   110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 281 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 360
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 361 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 427
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 428 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 496
Cdd:COG5048   341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1383482556 497 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 542
Cdd:COG5048   421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 435-487 4.30e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 4.30e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1383482556 435 GERPYVCDV--CGKTFRNNSGLKVHRrLH--------------------TGEKPYKCDVCGKAYISRSSLKNHKG 487
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYHM-LHghqnqklhenpspekmnifsAKDKPYRCEVCDKRYKNLNGLKYHRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 239-290 1.04e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.86  E-value: 1.04e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1383482556 239 GEKPYECG--ECGKAFRNSSGLRVHKR-------------------IHTGEKPYECDTCGKTFSNSSGLRVHK 290
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 50-262 3.15e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 3.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556  50 FPKWKILKEGKSSIREM---IDT-HTNAANIKLEQDDETSEKSFYPSTNTMHQTIPTEPNCTKQGEHTENING----NVH 121
Cdd:COG5189   214 LKKLSLIEEKKFPERVRsryIDIgHMMDTHQFYLEDVDLMDDDILGPSNEEMLYKYISPSQGSAELFEESSLGfdyeFIH 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 122 PA----HIADKKLHKCDECGKSFKYNSRLVQHKIMHTGEKryecddcrgTFRSSSSLRVHKrihtGEKPYKCD--ECGKA 195
Cdd:COG5189   294 KSvgnkEIRGGISTGEMIDVRKLPCTNSSSNGKLAHGGER---------NIDTPSRMLKVK----DGKPYKCPveGCNKK 360

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1383482556 196 YMSYSSLINHKsthsgekncKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHK 262
Cdd:COG5189   361 YKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 493-541 3.75e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.75e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1383482556 493 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 541
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
286-310 3.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.86e-04
                          10        20
                  ....*....|....*....|....*
gi 1383482556 286 LRVHKRIHTGEKPYECDECGKAFIT 310
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
258-282 8.46e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 8.46e-04
                          10        20
                  ....*....|....*....|....*
gi 1383482556 258 LRVHKRIHTGEKPYECDTCGKTFSN 282
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
173-196 1.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.13e-03
                          10        20
                  ....*....|....*....|....
gi 1383482556 173 SLRVHKRIHTGEKPYKCDECGKAY 196
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
230-254 1.32e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.32e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 230 LDQHKRIHTGEKPYECGECGKAFRN 254
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
370-394 1.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.44e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 370 LIVHKRIHTGEKPYKCDICGKAFSY 394
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
817-840 1.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.51e-03
                          10        20
                  ....*....|....*....|....
gi 1383482556 817 LDQHKRIHTGKKPYRCNDCGKAFN 840
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 490-570 1.77e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 490 MGEKPYKCSY--CEKSFNYSSALEQHkRIHTREKPfgcdecgKAFRNNSGLKvHKRIHTGERPYKCEECGKAYISLSSLI 567
Cdd:COG5189   345 KDGKPYKCPVegCNKKYKNQNGLKYH-MLHGHQNQ-------KLHENPSPEK-MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                  ...
gi 1383482556 568 NHK 570
Cdd:COG5189   416 YHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
649-674 2.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.13e-03
                          10        20
                  ....*....|....*....|....*.
gi 1383482556 649 SLKVHKRIHTGEKPYECDICGKAYIS 674
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 353-401 2.27e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 2.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1383482556 353 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDICGKAFSYSSGLAVH 401
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
538-562 2.40e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.40e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 538 LKVHKRIHTGERPYKCEECGKAYIS 562
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 602-682 6.15e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 6.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1383482556 602 LGEKPYKCDV--CEKSFNYTSLLSQHkRVHtrekpfecDRCEKVFRNNSSLKVHKRIHTGEKPYECDICGKAYISHSSLI 679
Cdd:COG5189   345 KDGKPYKCPVegCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                  ...
gi 1383482556 680 NHK 682
Cdd:COG5189   416 YHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
342-366 6.53e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.53e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 342 LIQHKVIHTGEKPYECDECGKAFRN 366
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-478 6.93e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.93e-03
                          10        20
                  ....*....|....*....|....*
gi 1383482556 454 LKVHRRLHTGEKPYKCDVCGKAYIS 478
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 714-766 9.55e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 39.32  E-value: 9.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1383482556 714 LGEKPFKC--VECGKSFSYSSLLSQHKR-------------------IHTGEKPYVCDWCGKAFRNSSGLTVHK 766
Cdd:COG5189   345 KDGKPYKCpvEGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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