|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
109-654 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 749.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 109 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTTLVAFPSSSVYPTkdeennPLE 185
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP-GKKGGYTSGT--FRTVLIA 262
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 263 CNVK----QMSKDAQP----SFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH 334
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 335 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 414
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 415 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 494
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 495 REISDHVLRMHRYRAPgeqdgdamplgsavdilatddpnfsQEDQQDtqiyekhdnllhgtkkkkEKMVSAAFMKKYIHV 574
Cdd:smart00350 393 RELAKHVVDLHRYSHP-------------------------EEDEAF------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 575 AK-IIKPVLTQESATYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 653
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 1484505971 654 F 654
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
298-652 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 602.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 298 QLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYrapgeqdgdamplgsavdilatddpnfsqe 537
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 538 dqqdtqiyekhdnllhgtkkkkekmvsAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTAR 616
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 1484505971 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
19-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 544.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 19 YLDFLDDEEdqgiYQSKVRELISDNQYR--LIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIdatYAKQYE 96
Cdd:COG1241 9 FEEFLRRYK----YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 97 EFYVGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTtlvafpsssvY 174
Cdd:COG1241 82 DAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------E 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 175 PTKDEE---NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY 251
Cdd:COG1241 150 PHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 252 TSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE 330
Cdd:COG1241 230 KSTIFDLYLEANSIEVEEKEfEEIEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 331 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCID 409
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 410 EFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQM 489
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 490 DPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilatddpnfsqedqqdtqIYEKHDNLLHGTKKKKEKMVSAAFMK 569
Cdd:COG1241 468 DEERDRELARHILKVHR-------------------------------------AGELLEQEIEEETEEVKPEIDPDLLR 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 570 KYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
Cdd:COG1241 511 KYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRL 587
|
...
gi 1484505971 649 VQY 651
Cdd:COG1241 588 VDS 590
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
12-651 |
4.70e-173 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 515.63 E-value: 4.70e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 12 LREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATY 91
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 92 AKQYEEFYVGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSS 171
Cdd:NF040949 81 AEEVAKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 172 SVYPtKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPG---KK 248
Cdd:NF040949 159 TVCP-VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 249 GgyTSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVER 327
Cdd:NF040949 238 G--SRPIFKNYIEANHIEVSQKElEEVEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 328 DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
Cdd:NF040949 314 VLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLD 487
Cdd:NF040949 394 IDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 488 QMDPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilatddpnfsqedqqdtqiyekhdnllhgTKKKKEKMVSAAF 567
Cdd:NF040949 474 KPNEERDRRLARHILDVHS------------------------------------------------GKEKVKPEIDPDL 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 568 MKKYIHVA-KIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAV 646
Cdd:NF040949 506 LKKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAI 585
|
....*
gi 1484505971 647 ELVQY 651
Cdd:NF040949 586 RLMLA 590
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
280-505 |
3.50e-130 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 387.66 E-value: 3.50e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 280 DIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVL 359
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 360 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 439
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1484505971 440 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 505
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
113-654 |
1.86e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 280.73 E-value: 1.86e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 113 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVafpssSVYPTKDEENNPL-------- 184
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 185 ---ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDK--------------------AKPGDRVQVVGTY 241
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGIL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 242 RCLPGKkggyTSGTFRTV---------LIACNVKQMSKDAQP-----------SFSAEDIAKIKKFSktRSKDIFDQLAK 301
Cdd:PTZ00111 373 KVTPIR----TSTTRRTLkslytyfvnVIHVKVINSTNANQPekglkylgnenDFSDLQVYKILELS--RNPMIYRILLD 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 302 SLAPSIHGHDYVKKAILCLLLGGVERDLENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRG 372
Cdd:PTZ00111 447 SFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKS 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 373 SSGVGLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAA 451
Cdd:PTZ00111 527 SSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILAS 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 452 ANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhryrapgeqdgdAMPLGSAVDILATDD 531
Cdd:PTZ00111 607 CNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK-------------DFLLPHMTGSGNDED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 532 PnfsqEDQQDTQIYEkhDNLLHgtKKKKEKMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRSQDSMSSDT--- 607
Cdd:PTZ00111 674 T----YDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdel 745
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1484505971 608 -----------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF 654
Cdd:PTZ00111 746 ehaqedddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTF 809
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-104 |
2.19e-17 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 78.10 E-value: 2.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 16 QRDYLDFLD----DEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASI--DA 89
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 1484505971 90 TYAKQYEEFYVGLEG 104
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
109-654 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 749.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 109 KHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRS---VHYCPATKKTIERRYSDLTTLVAFPSSSVYPTkdeennPLE 185
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPT------PFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP-GKKGGYTSGT--FRTVLIA 262
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 263 CNVK----QMSKDAQP----SFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH 334
Cdd:smart00350 155 NHVRkldyKRSFEDSSfsvqSLSDEEEEEIRKLSK--DPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 335 IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKM 414
Cdd:smart00350 233 IRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKM 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 415 SDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQD 494
Cdd:smart00350 313 DDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERD 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 495 REISDHVLRMHRYRAPgeqdgdamplgsavdilatddpnfsQEDQQDtqiyekhdnllhgtkkkkEKMVSAAFMKKYIHV 574
Cdd:smart00350 393 RELAKHVVDLHRYSHP-------------------------EEDEAF------------------EPPLSQEKLRKYIAY 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 575 AK-IIKPVLTQESATYIAEEYSRLRSQDSmSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAY 653
Cdd:smart00350 430 AReKIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
.
gi 1484505971 654 F 654
Cdd:smart00350 509 I 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
298-652 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 602.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 298 QLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYrapgeqdgdamplgsavdilatddpnfsqe 537
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 538 dqqdtqiyekhdnllhgtkkkkekmvsAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTAR 616
Cdd:cd17754 211 ---------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITAR 263
|
330 340 350
....*....|....*....|....*....|....*.
gi 1484505971 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17754 264 TLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
19-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 544.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 19 YLDFLDDEEdqgiYQSKVRELISDNQYR--LIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIdatYAKQYE 96
Cdd:COG1241 9 FEEFLRRYK----YRDEILELAQEYPEKrsLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLEP---YDVSLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 97 EFYVGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA--TKKTIERRYSDLTtlvafpsssvY 174
Cdd:COG1241 82 DAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ----------E 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 175 PTKDEE---NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY 251
Cdd:COG1241 150 PHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 252 TSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE 330
Cdd:COG1241 230 KSTIFDLYLEANSIEVEEKEfEEIEITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 331 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRGVVCID 409
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 410 EFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQM 489
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 490 DPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilatddpnfsqedqqdtqIYEKHDNLLHGTKKKKEKMVSAAFMK 569
Cdd:COG1241 468 DEERDRELARHILKVHR-------------------------------------AGELLEQEIEEETEEVKPEIDPDLLR 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 570 KYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTArtsPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
Cdd:COG1241 511 KYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV---PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRL 587
|
...
gi 1484505971 649 VQY 651
Cdd:COG1241 588 VDS 590
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
12-651 |
4.70e-173 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 515.63 E-value: 4.70e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 12 LREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATY 91
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 92 AKQYEEFYVGLEGSFgsKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSS 171
Cdd:NF040949 81 AEEVAKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 172 SVYPtKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPG---KK 248
Cdd:NF040949 159 TVCP-VCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 249 GgyTSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVER 327
Cdd:NF040949 238 G--SRPIFKNYIEANHIEVSQKElEEVEITEEDEEKILELAK--DPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 328 DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
Cdd:NF040949 314 VLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLD 487
Cdd:NF040949 394 IDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 488 QMDPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilatddpnfsqedqqdtqiyekhdnllhgTKKKKEKMVSAAF 567
Cdd:NF040949 474 KPNEERDRRLARHILDVHS------------------------------------------------GKEKVKPEIDPDL 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 568 MKKYIHVA-KIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAV 646
Cdd:NF040949 506 LKKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAI 585
|
....*
gi 1484505971 647 ELVQY 651
Cdd:NF040949 586 RLMLA 590
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
299-650 |
8.57e-144 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 426.37 E-value: 8.57e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17706 2 LADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17706 82 TAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDgdamplgsavdilatddpnfsqed 538
Cdd:cd17706 162 YNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQV------------------------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 539 qqdtqiyekhdnllhgTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQdsmsSDTARTSPVTARTL 618
Cdd:cd17706 218 ----------------KPEEDGIPIDIELLRKYILYARQIHPKISEEAREKLVRWYVELRKE----SERRSTIPITARQL 277
|
330 340 350
....*....|....*....|....*....|..
gi 1484505971 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17706 278 ESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVR 309
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
280-505 |
3.50e-130 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 387.66 E-value: 3.50e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 280 DIAKIKKFSKtrSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVL 359
Cdd:pfam00493 1 DEEEIKELAK--RPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 360 CTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH 439
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1484505971 440 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 505
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
299-652 |
5.36e-125 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 377.91 E-value: 5.36e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDlENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHryrapgeQDGDAMPlgSAVDILatdDPNfsqed 538
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVH-------QHNKQPD--SDFEPL---DPK----- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 539 qqdtqiyekhdnllhgtkkkkekmvsaaFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPvtaRTL 618
Cdd:cd17758 224 ----------------------------LLRAYIALAKRKRPTVPPALADYIVQAYVEMRQEAKRSKDFTFTTP---RTL 272
|
330 340 350
....*....|....*....|....*....|....
gi 1484505971 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17758 273 LAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
299-650 |
1.23e-120 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 366.71 E-value: 1.23e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17756 2 ISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17756 82 TASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAmplgsavdilatddpnfsqed 538
Cdd:cd17756 162 YDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQEN--------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 539 qqdtqiyekhdnllhgtkkkkEKMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRS---QDSMSSDTARTSPVT 614
Cdd:cd17756 221 ---------------------EGEIPISKLKRYIAYCRAkCAPRLSEEAAEKLSNHYVTIRKdvrQNELESDNRSSIPIT 279
|
330 340 350
....*....|....*....|....*....|....*.
gi 1484505971 615 ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17756 280 VRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQ 315
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
299-649 |
2.84e-118 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 360.53 E-value: 2.84e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 379 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGR 458
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRApgeqdgDAMplgsavdilatdDPNFSQED 538
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE------EAI------------EPPFTAEQ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 539 qqdtqiyekhdnllhgtkkkkekmvsaafMKKYIHVAKIIKPVLTQESATYIAEEYSRLRsQDSMSSDTARTSPVTARTL 618
Cdd:cd17757 224 -----------------------------LKRYIAYARTFKPKLTKEAKDELVEQYKELR-QDDASGSTRSSYRITVRQL 273
|
330 340 350
....*....|....*....|....*....|.
gi 1484505971 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELV 649
Cdd:cd17757 274 ESLIRLSEAIARLHCSDEVTPEHVEEAARLL 304
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
297-650 |
3.93e-114 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 349.83 E-value: 3.93e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 297 DQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 456
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 457 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRyrapgeqdgdamplgsavdilatddpnfsq 536
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHS------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 537 edqqdtqiyekhdnllHGTKKKKEKMVSAAFMKKYIHVA-KIIKPVLTQESATYIAEEYSRLRSQdsmSSDTARTSPVTA 615
Cdd:cd17761 211 ----------------GGEMREIKPEIDPDLLRKYIAYArKNVRPVLTEEAKQLIKDFYVEMRKS---GQETPSPVPITA 271
|
330 340 350
....*....|....*....|....*....|....*
gi 1484505971 616 RTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
Cdd:cd17761 272 RQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
299-652 |
1.28e-110 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 340.57 E-value: 1.28e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDLEN-GSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVG 377
Cdd:cd17755 2 LARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 378 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYG 457
Cdd:cd17755 82 LTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIGS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 458 RYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHryrapgeqdgdamplgsavdilatddpnfsqe 537
Cdd:cd17755 162 RYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLY-------------------------------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 538 dQQDTQIYEKHDnllhgtkkkkekMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRsqdSMSSDTARTSPVTAR 616
Cdd:cd17755 210 -LEDTPEHIQDE------------VLDVEVLTDYISYAREhIHPKLSEEAAQELVQAYVDMR---KMGSDARKRITATPR 273
|
330 340 350
....*....|....*....|....*....|....*.
gi 1484505971 617 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17755 274 QLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
301-649 |
1.33e-108 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 335.96 E-value: 1.33e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 301 KSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTA 380
Cdd:cd17753 4 NSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 381 AVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYD 460
Cdd:cd17753 84 SVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 461 QYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPgeqdgdamplgsavdilatddpnfsQEDQQ 540
Cdd:cd17753 164 PTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHP-------------------------ENDED 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 541 DTQIYEKHDNLLHGTkkKKEKMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRsQDSMSSDTArtsPVTARTLE 619
Cdd:cd17753 219 REGEEEKNQRQRPKE--TKVEPIPQELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLR-KESMATGSL---PITVRHLE 292
|
330 340 350
....*....|....*....|....*....|
gi 1484505971 620 TLIRLATAHAKARMSKTVDLQDAEEAVELV 649
Cdd:cd17753 293 SIIRISEAHAKMHLREYVSEEDVDMAIRVM 322
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
113-654 |
1.86e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 280.73 E-value: 1.86e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 113 PRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVafpssSVYPTKDEENNPL-------- 184
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEH-----YEYVIQGEVNEPLlcnecnsk 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 185 ---ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDK--------------------AKPGDRVQVVGTY 241
Cdd:PTZ00111 293 ytfELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEiymkdnevinlnlyddlidsVKTGDRVTVVGIL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 242 RCLPGKkggyTSGTFRTV---------LIACNVKQMSKDAQP-----------SFSAEDIAKIKKFSktRSKDIFDQLAK 301
Cdd:PTZ00111 373 KVTPIR----TSTTRRTLkslytyfvnVIHVKVINSTNANQPekglkylgnenDFSDLQVYKILELS--RNPMIYRILLD 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 302 SLAPSIHGHDYVKKAILCLLLGGVERDLENGSHI---------RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRG 372
Cdd:PTZ00111 447 SFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKSPdacykvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKS 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 373 SSGVGLTAAVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAA 451
Cdd:PTZ00111 527 SSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILAS 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 452 ANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRmhryrapgeqdgdAMPLGSAVDILATDD 531
Cdd:PTZ00111 607 CNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK-------------DFLLPHMTGSGNDED 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 532 PnfsqEDQQDTQIYEkhDNLLHgtKKKKEKMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRSQDSMSSDT--- 607
Cdd:PTZ00111 674 T----YDRSNTMHVE--DESLR--SEKDYNKNDLDMLRMYIKFSKLhCFPKLSDEAKKVITREYVKMRQGNFQTSNLdel 745
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1484505971 608 -----------------ARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF 654
Cdd:PTZ00111 746 ehaqedddddlyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTF 809
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
299-652 |
1.41e-73 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 242.45 E-value: 1.41e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGL 378
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 379 TaaVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPvYGR 458
Cdd:cd17760 82 T--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 459 YDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLrmhryrapgEQDGDAmplgsavdilatddpnfsqed 538
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---------ENKGEP--------------------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 539 qqdtqiyekhdnllhgtkKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATyIAEEYSRLRSQdsmsSDTARTSPVTARTL 618
Cdd:cd17760 209 ------------------SKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA-ILLRYYQLQRQ----SDCRNAARTTIRML 265
|
330 340 350
....*....|....*....|....*....|....
gi 1484505971 619 ETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17760 266 ESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
299-652 |
1.91e-69 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 231.27 E-value: 1.91e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 299 LAKSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKyaDDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDmDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVY 456
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 457 GRYDQYKTPMENIGLQDSLLSRFDLLFIMLDqmDPEQDReisDHVLRMHryrapgeqdgdamplgsavdilatddpnfsq 536
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLD--TPSEEH---DHLLSEH------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 537 edqqdtqiyekHDnllhgtkkkkekmvsaaFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQdsmsSDTARTSPVTA 615
Cdd:cd17759 205 -----------HQ-----------------LLRKYISYARqYVNPVLSKDASEALQEFYLELRKQ----NQLADSSPITT 252
|
330 340 350
....*....|....*....|....*....|....*..
gi 1484505971 616 RTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYA 652
Cdd:cd17759 253 RQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
114-245 |
4.98e-36 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 132.22 E-value: 4.98e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 114 RTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPtkdeenNPLETEygLSVY 193
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPTKCPNPECGNKDP------FKLVHE--KSKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1484505971 194 KDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP 245
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
567-650 |
2.39e-23 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 94.53 E-value: 2.39e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 567 FMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRSqdsMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 645
Cdd:pfam17855 2 LLRKYIAYAREkIKPKLSEEAREKLVDAYVELRK---ESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEA 78
|
....*
gi 1484505971 646 VELVQ 650
Cdd:pfam17855 79 IRLLK 83
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-104 |
2.19e-17 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 78.10 E-value: 2.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 16 QRDYLDFLD----DEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASI--DA 89
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 1484505971 90 TYAKQYEEFYVGLEG 104
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
297-512 |
1.50e-07 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 54.02 E-value: 1.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 297 DQLAKSLAPSIHGHDYVKKAIL-CLLLGGverdlengshirgdiNILLIGDPSVAKSQLLR---YVLCTAPRAIPTTgrg 372
Cdd:COG0714 4 ARLRAEIGKVYVGQEELIELVLiALLAGG---------------HLLLEGVPGVGKTTLAKalaRALGLPFIRIQFT--- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 373 ssgVGLTAA-VT----TDQETGERRLEAGAmVLAdrGVVCIDEFDKMSDmdRT--AIHEVMEQGRVTIakAGIHARLNAR 445
Cdd:COG0714 66 ---PDLLPSdILgtyiYDQQTGEFEFRPGP-LFA--NVLLADEINRAPP--KTqsALLEAMEERQVTI--PGGTYKLPEP 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 446 CSVLAAANPVygrydqyktpmENIG---LQDSLLSRFdLLFIMLDQMDPEQDREIsdhvLRMHRYRAPGE 512
Cdd:COG0714 136 FLVIATQNPI-----------EQEGtypLPEAQLDRF-LLKLYIGYPDAEEEREI----LRRHTGRHLAE 189
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
340-479 |
6.33e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.44 E-value: 6.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 340 NILLIGDPSVAKSQLLRYV---LCTAPRAIpttgrgssgVGLTAAVTTDQETGERRLEAGAMVLADR---------GVVC 407
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLaaaLSNRPVFY---------VQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAV 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1484505971 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAG--IHARLNARcSVLAAANPVYGRydqyktPMEnigLQDSLLSRF 479
Cdd:pfam07728 72 LDEINRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRG------LNE---LSPALRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
396-454 |
1.35e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 44.06 E-value: 1.35e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1484505971 396 GAMVLADRGVVCIDEfdkMSDMDRTAI---HEVMEQGRVTIAKAGIHARLNARCSVLAAANP 454
Cdd:pfam01078 100 GEISLAHNGVLFLDE---LPEFKRRVLeslRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
340-485 |
2.26e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 42.52 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1484505971 340 NILLIGDPSVAKSQLLRYVLCTAPRaipttgRGSSGVGLTAAVTT-------DQETGERRLEAGAMVLADRGVVCIDEFD 412
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFR------PGAPFLYLNASDLLeglvvaeLFGHFLVRLLFELAEKAKPGVLFIDEID 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1484505971 413 KMSDMDRTAIHEVMEQGRVTIAKagiharlNARCSVLAAANpvygrydqyktPMENIGLQDSLLSRFDLLFIM 485
Cdd:cd00009 95 SLSRGAQNALLRVLETLNDLRID-------RENVRVIGATN-----------RPLLGDLDRALYDRLDIRIVI 149
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
396-454 |
1.41e-03 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 41.95 E-value: 1.41e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1484505971 396 GAMVLADRGVVCIDEfdkMSDMDRTAIhEV----MEQGRVTIAKAGIHARLNARCSVLAAANP 454
Cdd:COG0606 290 GEISLAHNGVLFLDE---LPEFSRRVL-EAlrqpLEDGEVTISRANGSVTYPARFQLVAAMNP 348
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