|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00399 |
PTZ00399 |
cysteinyl-tRNA-synthetase; Provisional |
1-647 |
0e+00 |
|
cysteinyl-tRNA-synthetase; Provisional
Pssm-ID: 240402 [Multi-domain] Cd Length: 651 Bit Score: 686.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNHLfeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:PTZ00399 104 MNITDIDDKIIKRAREEKL------------------------------------------------------------- 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltgeevnscvevlleeakdllsdwldstlgcdvtdnSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFV 160
Cdd:PTZ00399 123 -------------------------------------SIFLELARKWEKEFFEDMKALNVRPPDVITRVSEYVPEIVDFI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 QKIVDNGYGYVSNGSVYFDTAKFASSeKHSYGKLVPEAVGDQKALQEGEGDLSISAdrlSEKRSPNDFALWKASKPGEPS 240
Cdd:PTZ00399 166 QKIIDNGFAYESNGSVYFDVEAFRKA-GHVYPKLEPESVADEDRIAEGEGALGKVS---GEKRSPNDFALWKASKPGEPS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 WPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:PTZ00399 242 WDSPWGKGRPGWHIECSAMASNILGDPIDIHSGGIDLKFPHHDNELAQSEAYFDKHQWVNYFLHSGHLHIKGLKMSKSLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVdiTGQFEKWGEEEAELNK 400
Cdd:PTZ00399 322 NFITIRQALSKYTARQIRLLFLLHKWDKPMNYSDESMDEAIEKDKVFFNFFANVKIKLRESE--LTSPQKWTQHDFELNE 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 401 NFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAArkavRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVG 480
Cdd:PTZ00399 400 LFEETKSAVHAALLDNFDTPEALQALQKLISATNTYLNS----GEQPSAPLLRSVAQYVTKILSIFGLVEGSDGLGSQGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 481 GpgtslSLEATVMPYLQVLSEFREGVRKIAR--------EQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDR 552
Cdd:PTZ00399 476 N-----STSENFKPLLEALLRFRDEVRDAAKaemklislDKKKKQLLQLCDKLRDEWLPNLGIRIEDKPDGPSVWKLDDK 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 553 NTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKL 632
Cdd:PTZ00399 551 EELQREKEEKEALKEQKRLRKLKKQEEKKKKELEKLEKAKIPPAEFFKRQEDKYSAFDETGLPTHDADGEEISKKERKKL 630
|
650
....*....|....*
gi 1802776421 633 KKLFEAQEKLYKEYL 647
Cdd:PTZ00399 631 SKEYDKQAKLHEEYL 645
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
1-540 |
1.43e-119 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 364.04 E-value: 1.43e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNhlfeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:COG0215 65 RNITDVDDKIIKRAAEE--------------------------------------------------------------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltGEEVNscvevlleeakdllsdwldstlgcDVTDnsifsklpkFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFV 160
Cdd:COG0215 82 ---GESIW------------------------ELAE---------RYIAAFHEDMDALGVLPPDIEPRATEHIPEMIELI 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 QKIVDNGYGYVSNGSVYFDTAKFassekHSYGKL---VPEAvgdqkaLQEGEgdlsiSADRLSEKRSPNDFALWKASKPG 237
Cdd:COG0215 126 ERLIEKGHAYEADGDVYFDVRSF-----PDYGKLsgrNLDD------LRAGA-----RVEVDEEKRDPLDFALWKAAKPG 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 238 EPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDcWVRYFLHTGHLTIAGCKMSK 317
Cdd:COG0215 190 EPSWDSPWGRGRPGWHIECSAMSTKYLGETFDIHGGGIDLIFPHHENEIAQSEAATGKP-FARYWMHNGFLTVNGEKMSK 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 318 SLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQ-YEKfLNEFFLNVKDILRAPVDITGQFEKWgeeea 396
Cdd:COG0215 269 SLGNFFTVRDLLKKYDPEVLRFFLLSAHYRSPLDFSEEALEEAEKaLER-LYNALRRLEEALGAADSSAEEIEEL----- 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 397 elnknfydkKTAIHKALCDNVDTRTVMEEMRALVSQCNlymaarKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLg 476
Cdd:COG0215 343 ---------REEFIAAMDDDFNTPEALAVLFELVREIN------KALDEGEDKAALAALAALLRALGGVLGLLLLEPEA- 406
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802776421 477 fpVGGPGTSLSLEATVMPYLQvlsefregVRKIAREQKvpeILQLSDALRDNILpELGVRFEDH 540
Cdd:COG0215 407 --WQGAAEDELLDALIEALIE--------ERAEARKAK---DFARADRIRDELA-ALGIVLEDT 456
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
100-365 |
2.16e-109 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 332.03 E-value: 2.16e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 100 DLLSDWLDStLGCDVT--------DNSI----------FSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQ 161
Cdd:pfam01406 35 DVLRRYLQA-LGYDVQfvqnftdiDDKIikrarqegesFRQLAARFIEAYTKDMDALNVLPPDLEPRVTEHIDEIIEFIE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 162 KIVDNGYGYVS-NGSVYFDTAKFassekHSYGKLVPEAVGDQKALQEGEGDlsisadrlSEKRSPNDFALWKASKPGEPS 240
Cdd:pfam01406 114 RLIKKGYAYVSdNGDVYFDVSSF-----PDYGKLSGQNLEQLEAGARGEVS--------EGKRDPLDFALWKASKEGEPS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 WPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDcWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:pfam01406 181 WDSPWGKGRPGWHIECSAMARKYLGDQIDIHGGGIDLAFPHHENEIAQSEAAFDKQ-LANYWLHNGHVMIDGEKMSKSLG 259
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYSsntmESALQYEK 365
Cdd:pfam01406 260 NFFTIRDVLKRYDPEILRYFLLSVHYRSPLDFS----EELLEQAK 300
|
|
| cysS |
TIGR00435 |
cysteinyl-tRNA synthetase; This model finds the cysteinyl-tRNA synthetase from most but not ... |
131-539 |
1.73e-100 |
|
cysteinyl-tRNA synthetase; This model finds the cysteinyl-tRNA synthetase from most but not from all species. The enzyme from one archaeal species, Archaeoglobus fulgidus, is found but the equivalent enzymes from some other Archaea, including Methanococcus jannaschii, are not found, although biochemical evidence suggests that tRNA(Cys) in these species are charged directly with Cys rather than through a misacylation and correction pathway as for tRNA(Gln). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273076 [Multi-domain] Cd Length: 464 Bit Score: 314.71 E-value: 1.73e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 131 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS-NGSVYFDTAKFassekHSYGKLvpeAVGDQKALQEGE 209
Cdd:TIGR00435 95 YFEDMKALNVLPPDLEPRATEHIDEIIEFIEQLIEKGYAYVSdNGDVYFDVSKF-----KDYGKL---SKQDLDQLEAGA 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 210 GDLSISAdrlseKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQS 289
Cdd:TIGR00435 167 RVDVDEA-----KRNKLDFVLWKSSKEGEPKWDSPWGKGRPGWHIECSAMNDKYLGDQIDIHGGGVDLIFPHHENEIAQS 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 290 EAYFeNDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSsntmESALQYEKFLNE 369
Cdd:TIGR00435 242 EAAF-GKQLAKYWMHNGFLMIDNEKMSKSLGNFFTVRDVLKNYDPEILRYFLLSVHYRSPLDFS----EELLEAAKNALE 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 370 FFLNVKDILRApvDITGQFEkWGEEEAELNKNFYDkktAIHKALCDNVDTRTVMEEMRALVSQCNLYMAarkavrkrpNQ 449
Cdd:TIGR00435 317 RLYKALRVLDT--SLAYSGN-QSLNKFPDEKEFEA---RFVEAMDDDLNTANALAVLFELAKSINLTFV---------SK 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 450 ALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPylqvlsefregvRKIAREQKVpeiLQLSDALRDNi 529
Cdd:TIGR00435 382 ADAALLIEHLIFLESRLGLLLGLPSKPVQAGSNDDLGEIEALIEE------------RSIARKEKD---FAKADEIRDE- 445
|
410
....*....|
gi 1802776421 530 LPELGVRFED 539
Cdd:TIGR00435 446 LAKKGIVLED 455
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
1-353 |
4.67e-65 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 213.21 E-value: 4.67e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNHLFeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:cd00672 63 QNITDIDDKIIKRAREEGLS------------------------------------------------------------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltgeevnscvevlleeakdllsdwldstlgcdvtdnsiFSKLPKFWEGDFHRDMEALNVLPPDVLTRVseyvpeivnfv 160
Cdd:cd00672 83 ---------------------------------------WKEVADYYTKEFFEDMKALNVLPPDVVPRV----------- 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 qkivdngygyvsngsvyfdtakfassekhsygklvpeavgdqkalqegegdlsisadrlsekrspndfalwkaskpgeps 240
Cdd:cd00672 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 wpcpwgkgrpgWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFeNDCWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:cd00672 113 -----------WHIECSAMAMKYLGETFDIHGGGVDLIFPHHENEIAQSEAAT-GKPFARYWLHTGHLTIDGEKMSKSLG 180
|
330 340 350
....*....|....*....|....*....|...
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYS 353
Cdd:cd00672 181 NFITVRDALKKYDPEVLRLALLSSHYRSPLDFS 213
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00399 |
PTZ00399 |
cysteinyl-tRNA-synthetase; Provisional |
1-647 |
0e+00 |
|
cysteinyl-tRNA-synthetase; Provisional
Pssm-ID: 240402 [Multi-domain] Cd Length: 651 Bit Score: 686.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNHLfeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:PTZ00399 104 MNITDIDDKIIKRAREEKL------------------------------------------------------------- 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltgeevnscvevlleeakdllsdwldstlgcdvtdnSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFV 160
Cdd:PTZ00399 123 -------------------------------------SIFLELARKWEKEFFEDMKALNVRPPDVITRVSEYVPEIVDFI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 QKIVDNGYGYVSNGSVYFDTAKFASSeKHSYGKLVPEAVGDQKALQEGEGDLSISAdrlSEKRSPNDFALWKASKPGEPS 240
Cdd:PTZ00399 166 QKIIDNGFAYESNGSVYFDVEAFRKA-GHVYPKLEPESVADEDRIAEGEGALGKVS---GEKRSPNDFALWKASKPGEPS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 WPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:PTZ00399 242 WDSPWGKGRPGWHIECSAMASNILGDPIDIHSGGIDLKFPHHDNELAQSEAYFDKHQWVNYFLHSGHLHIKGLKMSKSLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVdiTGQFEKWGEEEAELNK 400
Cdd:PTZ00399 322 NFITIRQALSKYTARQIRLLFLLHKWDKPMNYSDESMDEAIEKDKVFFNFFANVKIKLRESE--LTSPQKWTQHDFELNE 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 401 NFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAArkavRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVG 480
Cdd:PTZ00399 400 LFEETKSAVHAALLDNFDTPEALQALQKLISATNTYLNS----GEQPSAPLLRSVAQYVTKILSIFGLVEGSDGLGSQGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 481 GpgtslSLEATVMPYLQVLSEFREGVRKIAR--------EQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDR 552
Cdd:PTZ00399 476 N-----STSENFKPLLEALLRFRDEVRDAAKaemklislDKKKKQLLQLCDKLRDEWLPNLGIRIEDKPDGPSVWKLDDK 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 553 NTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKL 632
Cdd:PTZ00399 551 EELQREKEEKEALKEQKRLRKLKKQEEKKKKELEKLEKAKIPPAEFFKRQEDKYSAFDETGLPTHDADGEEISKKERKKL 630
|
650
....*....|....*
gi 1802776421 633 KKLFEAQEKLYKEYL 647
Cdd:PTZ00399 631 SKEYDKQAKLHEEYL 645
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
1-540 |
1.43e-119 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 364.04 E-value: 1.43e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNhlfeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:COG0215 65 RNITDVDDKIIKRAAEE--------------------------------------------------------------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltGEEVNscvevlleeakdllsdwldstlgcDVTDnsifsklpkFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFV 160
Cdd:COG0215 82 ---GESIW------------------------ELAE---------RYIAAFHEDMDALGVLPPDIEPRATEHIPEMIELI 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 QKIVDNGYGYVSNGSVYFDTAKFassekHSYGKL---VPEAvgdqkaLQEGEgdlsiSADRLSEKRSPNDFALWKASKPG 237
Cdd:COG0215 126 ERLIEKGHAYEADGDVYFDVRSF-----PDYGKLsgrNLDD------LRAGA-----RVEVDEEKRDPLDFALWKAAKPG 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 238 EPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDcWVRYFLHTGHLTIAGCKMSK 317
Cdd:COG0215 190 EPSWDSPWGRGRPGWHIECSAMSTKYLGETFDIHGGGIDLIFPHHENEIAQSEAATGKP-FARYWMHNGFLTVNGEKMSK 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 318 SLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQ-YEKfLNEFFLNVKDILRAPVDITGQFEKWgeeea 396
Cdd:COG0215 269 SLGNFFTVRDLLKKYDPEVLRFFLLSAHYRSPLDFSEEALEEAEKaLER-LYNALRRLEEALGAADSSAEEIEEL----- 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 397 elnknfydkKTAIHKALCDNVDTRTVMEEMRALVSQCNlymaarKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLg 476
Cdd:COG0215 343 ---------REEFIAAMDDDFNTPEALAVLFELVREIN------KALDEGEDKAALAALAALLRALGGVLGLLLLEPEA- 406
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802776421 477 fpVGGPGTSLSLEATVMPYLQvlsefregVRKIAREQKvpeILQLSDALRDNILpELGVRFEDH 540
Cdd:COG0215 407 --WQGAAEDELLDALIEALIE--------ERAEARKAK---DFARADRIRDELA-ALGIVLEDT 456
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
100-365 |
2.16e-109 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 332.03 E-value: 2.16e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 100 DLLSDWLDStLGCDVT--------DNSI----------FSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQ 161
Cdd:pfam01406 35 DVLRRYLQA-LGYDVQfvqnftdiDDKIikrarqegesFRQLAARFIEAYTKDMDALNVLPPDLEPRVTEHIDEIIEFIE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 162 KIVDNGYGYVS-NGSVYFDTAKFassekHSYGKLVPEAVGDQKALQEGEGDlsisadrlSEKRSPNDFALWKASKPGEPS 240
Cdd:pfam01406 114 RLIKKGYAYVSdNGDVYFDVSSF-----PDYGKLSGQNLEQLEAGARGEVS--------EGKRDPLDFALWKASKEGEPS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 WPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDcWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:pfam01406 181 WDSPWGKGRPGWHIECSAMARKYLGDQIDIHGGGIDLAFPHHENEIAQSEAAFDKQ-LANYWLHNGHVMIDGEKMSKSLG 259
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYSsntmESALQYEK 365
Cdd:pfam01406 260 NFFTIRDVLKRYDPEILRYFLLSVHYRSPLDFS----EELLEQAK 300
|
|
| cysS |
TIGR00435 |
cysteinyl-tRNA synthetase; This model finds the cysteinyl-tRNA synthetase from most but not ... |
131-539 |
1.73e-100 |
|
cysteinyl-tRNA synthetase; This model finds the cysteinyl-tRNA synthetase from most but not from all species. The enzyme from one archaeal species, Archaeoglobus fulgidus, is found but the equivalent enzymes from some other Archaea, including Methanococcus jannaschii, are not found, although biochemical evidence suggests that tRNA(Cys) in these species are charged directly with Cys rather than through a misacylation and correction pathway as for tRNA(Gln). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273076 [Multi-domain] Cd Length: 464 Bit Score: 314.71 E-value: 1.73e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 131 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS-NGSVYFDTAKFassekHSYGKLvpeAVGDQKALQEGE 209
Cdd:TIGR00435 95 YFEDMKALNVLPPDLEPRATEHIDEIIEFIEQLIEKGYAYVSdNGDVYFDVSKF-----KDYGKL---SKQDLDQLEAGA 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 210 GDLSISAdrlseKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQS 289
Cdd:TIGR00435 167 RVDVDEA-----KRNKLDFVLWKSSKEGEPKWDSPWGKGRPGWHIECSAMNDKYLGDQIDIHGGGVDLIFPHHENEIAQS 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 290 EAYFeNDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSsntmESALQYEKFLNE 369
Cdd:TIGR00435 242 EAAF-GKQLAKYWMHNGFLMIDNEKMSKSLGNFFTVRDVLKNYDPEILRYFLLSVHYRSPLDFS----EELLEAAKNALE 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 370 FFLNVKDILRApvDITGQFEkWGEEEAELNKNFYDkktAIHKALCDNVDTRTVMEEMRALVSQCNLYMAarkavrkrpNQ 449
Cdd:TIGR00435 317 RLYKALRVLDT--SLAYSGN-QSLNKFPDEKEFEA---RFVEAMDDDLNTANALAVLFELAKSINLTFV---------SK 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 450 ALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPylqvlsefregvRKIAREQKVpeiLQLSDALRDNi 529
Cdd:TIGR00435 382 ADAALLIEHLIFLESRLGLLLGLPSKPVQAGSNDDLGEIEALIEE------------RSIARKEKD---FAKADEIRDE- 445
|
410
....*....|
gi 1802776421 530 LPELGVRFED 539
Cdd:TIGR00435 446 LAKKGIVLED 455
|
|
| PLN02946 |
PLN02946 |
cysteine-tRNA ligase |
123-360 |
3.79e-69 |
|
cysteine-tRNA ligase
Pssm-ID: 178532 [Multi-domain] Cd Length: 557 Bit Score: 235.21 E-value: 3.79e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 123 LPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASsekhsYGKLVPEAVGDQ 202
Cdd:PLN02946 146 LSRRYCEEFLSDMAYLHCLPPSVEPRVSDHIPQIIDMIKQILDNGCAYRVDGDVYFSVDKFPE-----YGKLSGRKLEDN 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 203 KAlqeGEgdlSISADrlSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHH 282
Cdd:PLN02946 221 RA---GE---RVAVD--SRKKNPADFALWKAAKEGEPFWDSPWGPGRPGWHIECSAMSAAYLGHSFDIHGGGMDLVFPHH 292
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1802776421 283 DNELAQSEAYFEnDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESA 360
Cdd:PLN02946 293 ENEIAQSCAACC-DSNISYWIHNGFVTVDSEKMSKSLGNFFTIRQVIDLYHPLALRLFLLGTHYRSPINYSDVQLESA 369
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
1-353 |
4.67e-65 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 213.21 E-value: 4.67e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 1 MNITDIDDKIIKRARQNHLFeqyrekrpeaaqlledvqaalkpfsvklnettdpdkkqmleriqhavqlateplekavqs 80
Cdd:cd00672 63 QNITDIDDKIIKRAREEGLS------------------------------------------------------------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 81 rltgeevnscvevlleeakdllsdwldstlgcdvtdnsiFSKLPKFWEGDFHRDMEALNVLPPDVLTRVseyvpeivnfv 160
Cdd:cd00672 83 ---------------------------------------WKEVADYYTKEFFEDMKALNVLPPDVVPRV----------- 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 161 qkivdngygyvsngsvyfdtakfassekhsygklvpeavgdqkalqegegdlsisadrlsekrspndfalwkaskpgeps 240
Cdd:cd00672 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 241 wpcpwgkgrpgWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFeNDCWVRYFLHTGHLTIAGCKMSKSLK 320
Cdd:cd00672 113 -----------WHIECSAMAMKYLGETFDIHGGGVDLIFPHHENEIAQSEAAT-GKPFARYWLHTGHLTIDGEKMSKSLG 180
|
330 340 350
....*....|....*....|....*....|...
gi 1802776421 321 NFITIKDALKKHSARQLRLAFLMHSWKDTLDYS 353
Cdd:cd00672 181 NFITVRDALKKYDPEVLRLALLSSHYRSPLDFS 213
|
|
| cysS |
PRK14535 |
cysteinyl-tRNA synthetase; Provisional |
132-360 |
6.07e-53 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 173001 [Multi-domain] Cd Length: 699 Bit Score: 193.78 E-value: 6.07e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 132 HRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGY-VSNGSVYFDTAKFASsekhsYGKLVPEAVGDQKALQEGEG 210
Cdd:PRK14535 323 HEDADALGVLRPDIEPKATENIPQMIAMIETLIQNGKAYpAANGDVYYAVREFAA-----YGQLSGKSLDDLRAGERVEV 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 211 DlsisadrlSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSE 290
Cdd:PRK14535 398 D--------GFKRDPLDFVLWKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSV 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 291 AYFENDC---------------WVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSN 355
Cdd:PRK14535 470 GATGHTCghhhaqthhgqsiasHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDA 549
|
....*
gi 1802776421 356 TMESA 360
Cdd:PRK14535 550 HLDDA 554
|
|
| mycothiol_MshC |
TIGR03447 |
cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Members of this ... |
131-362 |
9.81e-50 |
|
cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Members of this protein family are MshC, l-cysteine:1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, an enzyme that uses ATP to ligate a Cys residue to a mycothiol precursor molecule, in the second to last step in mycothiol biosynthesis. This enzyme shows considerable homology to Cys--tRNA ligases, and many instances are misannotated as such. Mycothiol is found in Mycobacterium tuberculosis, Corynebacterium glutamicum, Streptomyces coelicolor, and various other members of the Actinobacteria. Mycothiol is an analog to glutathione. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 132488 [Multi-domain] Cd Length: 411 Bit Score: 178.77 E-value: 9.81e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 131 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYV----SNGSVYFDTAkfaSSEKHSYGKLVPEAVGDQKALQ 206
Cdd:TIGR03447 110 FREDMEALRVLPPRDYIGAVESIDEVVEMVEKLLASGAAYIvegpEYPDVYFSID---ATEQFGYESGYDRATMLELFAE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 207 EGeGDlsisADRLSeKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNEL 286
Cdd:TIGR03447 187 RG-GD----PDRPG-KRDPLDALLWRAAREGEPSWDSPFGRGRPGWHIECSAIALNRLGAGFDIQGGGSDLIFPHHEFSA 260
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1802776421 287 AQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDaLKK--HSARQLRLAFLMHSWKDTLDYSSNTMESALQ 362
Cdd:TIGR03447 261 AHAEAATGVRRMARHYVHAGMIGLDGEKMSKSLGNLVFVSK-LRAagVDPAAIRLGLLAGHYRQDRDWTDAVLAEAEA 337
|
|
| PRK12418 |
PRK12418 |
cysteinyl-tRNA synthetase; Provisional |
131-362 |
3.40e-49 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 183518 [Multi-domain] Cd Length: 384 Bit Score: 176.27 E-value: 3.40e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 131 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYV----SNGSVYFDTAkfassekhsygklVPEAVGDQKALQ 206
Cdd:PRK12418 83 FREDMEALRVLPPRDYVGAVESIPEVVELVEKLLASGAAYVvddeEYPDVYFSVD-------------ATPQFGYESGYD 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 207 EGEGdLSISADRLSE-----KRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPH 281
Cdd:PRK12418 150 RATM-LELFAERGGDpdrpgKRDPLDALLWRAARPGEPSWPSPFGPGRPGWHIECSAIALNRLGSGFDIQGGGSDLIFPH 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 282 HDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKdALKK--HSARQLRLAFLMHSWKDTLDYSSNTMES 359
Cdd:PRK12418 229 HEFSAAHAEAATGERRFARHYVHAGMIGLDGEKMSKSRGNLVFVS-RLRAagVDPAAIRLALLAGHYRADREWTDAVLAE 307
|
...
gi 1802776421 360 ALQ 362
Cdd:PRK12418 308 AEA 310
|
|
| cysS |
PRK14536 |
cysteinyl-tRNA synthetase; Provisional |
122-474 |
1.06e-44 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 184731 [Multi-domain] Cd Length: 490 Bit Score: 166.63 E-value: 1.06e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 122 KLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASsekhsYGKLVPEAVGD 201
Cdd:PRK14536 98 EIAAHYTAAFFRDTARLNIERPSIVCNATEHIQDMIALIKRLEARGHTYCAGGNVYFDIRTFPS-----YGSLASAAVED 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 202 qkaLQEGEgdlSISADrlSEKRSPNDFALWKASKPGEP---SWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLR 278
Cdd:PRK14536 173 ---LQAGA---RIEHD--TNKRNPHDFVLWFTRSKFENhalTWDSPWGRGYPGWHIECSAMSMKYLGEQCDIHIGGVDHI 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 279 FPHHDNELAQSEAyFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKK-HSARQLRLAFLMHSWKDTLDYSSNTM 357
Cdd:PRK14536 245 RVHHTNEIAQCEA-ATGKPWVRYWLHHEFLLMNKGKMSKSAGQFLTLSSLQEKgFQPLDYRFFLLGGHYRSQLAFSWEAL 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 358 ESALQYEKFLNEFFLNVKDILRAPVDITGQF------EKWGEEEAELNKNFYDKKTAihkALCDNVDTRTVMEEMRALVS 431
Cdd:PRK14536 324 KTAKAARRSLVRRVARVVDAARATTGSVRGTlaecaaERVAESRASESELLLTDFRA---ALEDDFSTPKALSELQKLVK 400
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1802776421 432 QCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSS 474
Cdd:PRK14536 401 DTSVPPSLCLSVLQAMDTVLGLGLIQEATASLSAQVPAGPSEE 443
|
|
| cysS |
PRK14534 |
cysteinyl-tRNA synthetase; Provisional |
122-404 |
2.06e-34 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 173000 [Multi-domain] Cd Length: 481 Bit Score: 136.90 E-value: 2.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 122 KLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFassekHSYGKLVPEAVGD 201
Cdd:PRK14534 96 EISRFFTEAFFDDCKKLNIVYPDKVLVASEYIPIMIEVVKVLEENGFTYFVNGNVYFDTSCF-----KSYGQMAGINLND 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 202 QKALQEGEGDLSISadrlseKRSPNDFALWKAS---KPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLR 278
Cdd:PRK14534 171 FKDMSVSRVEIDKS------KRNKSDFVLWFTNskfKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKSTLDIHLGGVDHI 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 279 FPHHDNELAQSEAYFeNDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKH-SARQLRLAFLMHSWKDTLDYSSNTM 357
Cdd:PRK14534 245 GVHHINEIAIAECYL-NKKWCDMFVHGEFLIMEYEKMSKSNNNFITIKDLEDQGfSPLDFRYFCLTAHYRTQLKFTFNNL 323
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1802776421 358 E-SALQYEKFLNE--FFLNVKDilraPVDITGQFEKWGEEEAELNKNFYD 404
Cdd:PRK14534 324 KaCKIARENMLNKltYFYSSLD----QFDLNLLNKDLENIEFSLEKEYYD 369
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
291-426 |
1.07e-07 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 55.26 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 291 AYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLaFLMHS---WKDtLDYSSNTMESAL-QYEKF 366
Cdd:PRK12300 554 AIFPEEKWPRGIVVNGFVLLEGKKMSKSKGNVIPLRKAIEEYGADVVRL-YLTSSaelLQD-ADWREKEVESVRrQLERF 631
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 367 LnEFFLNVKDIlrAPVDITGQFEKWgeEEAELNKNFydKKTaiHKALcDNVDTRTVMEEM 426
Cdd:PRK12300 632 Y-ELAKELIEI--GGEEELRFIDKW--LLSRLNRII--KET--TEAM-ESFQTRDAVQEA 681
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
275-361 |
1.07e-05 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 48.91 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 275 FDLRFPHHD---NELAQS----EAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRlaFLMHSWK 347
Cdd:PLN02959 672 FDLRVSGKDliqNHLTFAiynhTAIWAEEHWPRGFRCNGHLMLNSEKMSKSTGNFLTLRQAIEEFSADATR--FALADAG 749
|
90
....*....|....*..
gi 1802776421 348 DTLD---YSSNTMESAL 361
Cdd:PLN02959 750 DGVDdanFVFETANAAI 766
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
299-345 |
1.61e-04 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 44.06 E-value: 1.61e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1802776421 299 VRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHS 345
Cdd:cd00814 265 PTRIVAHGYLTVEGKKMSKSRGNVVDPDDLLERYGADALRYYLLRER 311
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
305-345 |
5.98e-04 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 42.66 E-value: 5.98e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1802776421 305 TGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHS 345
Cdd:pfam09334 315 HGYLTYEGGKMSKSRGNVVWPSEALDRFPPDALRYYLARNR 355
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
251-319 |
1.03e-03 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 39.77 E-value: 1.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802776421 251 GWHIECSAMAGTLLGASMDIHGGGFDLRFpHHDNELAQSEAYfeNDCWVRYFLHTGHLTIA-GCKMSKSL 319
Cdd:cd00802 77 EYMFLQAADFLLLYETECDIHLGGSDQLG-HIELGLELLKKA--GGPARPFGLTFGRVMGAdGTKMSKSK 143
|
|
| |
