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Conserved domains on  [gi|1802983044|ref|NP_001365086|]
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X-ray radiation resistance-associated protein 1 isoform 4 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
103-283 2.03e-18

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 2.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 103 SDLCTINVSGLKFSKAkENDFKHFHSVIYINASENL---LPlEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLS 179
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQltdLP-EPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 180 FNSLTvEAICDLGILPHLRVLLLTGNGLTSLPPNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSNpscFASLAG 259
Cdd:COG4886   191 NNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPEPLA------------------NLTNLETLDLSNNQLTD---LPELGN 248

                         170       180
                  ....*....|....*....|....
gi 1802983044 260 LRRLKKLSLDENRIIRIPYLQQVQ 283
Cdd:COG4886   249 LTNLEELDLSNNQLTDLPPLANLT 272
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
103-283 2.03e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 2.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 103 SDLCTINVSGLKFSKAkENDFKHFHSVIYINASENL---LPlEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLS 179
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQltdLP-EPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 180 FNSLTvEAICDLGILPHLRVLLLTGNGLTSLPPNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSNpscFASLAG 259
Cdd:COG4886   191 NNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPEPLA------------------NLTNLETLDLSNNQLTD---LPELGN 248

                         170       180
                  ....*....|....*....|....
gi 1802983044 260 LRRLKKLSLDENRIIRIPYLQQVQ 283
Cdd:COG4886   249 LTNLEELDLSNNQLTDLPPLANLT 272
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 103-278 9.83e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.46  E-value: 9.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 103 SDLCTINVSGLKFSKAKENDFKHFHSVIYINASENLL----PLEAFHTFPALKELDLAFNGIkTIYVKYGDFKLLEFLDL 178
Cdd:PLN00113   69 SRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLsgpiPDDIFTTSSSLRYLNLSNNNF-TGSIPRGSIPNLETLDL 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 179 SFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNlavaeqeaSVTSLTSkryilrfpaLETLMLDDNRLSNpSCFASLA 258
Cdd:PLN00113  148 SNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPN--------SLTNLTS---------LEFLTLASNQLVG-QIPRELG 209

                         170       180
                  ....*....|....*....|.
gi 1802983044 259 GLRRLKKLSLDENRII-RIPY 278
Cdd:PLN00113  210 QMKSLKWIYLGYNNLSgEIPY 230
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 178-276 9.82e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 9.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 178 LSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPpNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSnpsCFASL 257
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIE-NLE------------------FLTNLTHLYLQNNQIE---KIENL 64

                          90
                  ....*....|....*....
gi 1802983044 258 AGLRRLKKLSLDENRIIRI 276
Cdd:cd21340    65 ENLVNLKKLYLGGNRISVV 83
LRR_8 pfam13855
Leucine rich repeat;
195-273 1.24e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 195 PHLRVLLLTGNGLTSLPPnlavaeqeasvtsltskRYILRFPALETLMLDDNRLS--NPSCFaslAGLRRLKKLSLDENR 272
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDD-----------------GAFKGLSNLKVLDLSNNLLTtlSPGAF---SGLPSLRYLDLSGNR 60


                  .
gi 1802983044 273 I 273
Cdd:pfam13855  61 L 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
103-283 2.03e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 2.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 103 SDLCTINVSGLKFSKAkENDFKHFHSVIYINASENL---LPlEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLS 179
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQltdLP-EPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 180 FNSLTvEAICDLGILPHLRVLLLTGNGLTSLPPNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSNpscFASLAG 259
Cdd:COG4886   191 NNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPEPLA------------------NLTNLETLDLSNNQLTD---LPELGN 248

                         170       180
                  ....*....|....*....|....
gi 1802983044 260 LRRLKKLSLDENRIIRIPYLQQVQ 283
Cdd:COG4886   249 LTNLEELDLSNNQLTDLPPLANLT 272
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
121-281 6.18e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.83  E-value: 6.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 121 NDFKHFHSVIYINASENL---LPlEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTV--EAICDlgiLP 195
Cdd:COG4886   107 EELSNLTNLESLDLSGNQltdLP-EELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDlpEELGN---LT 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 196 HLRVLLLTGNGLTSLPPNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSNPScfASLAGLRRLKKLSLDENRIIR 275
Cdd:COG4886   183 NLKELDLSNNQITDLPEPLG------------------NLTNLEELDLSGNQLTDLP--EPLANLTNLETLDLSNNQLTD 242


                  ....*.
gi 1802983044 276 IPYLQQ 281
Cdd:COG4886   243 LPELGN 248
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
150-277 5.38e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.10  E-value: 5.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 150 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSltveaicDLGILPHLRVLLLTGNGLTSLPPNLAVAEQ-------EAS 222
Cdd:COG4886    75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELANLTNlkeldlsNNQ 147

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1802983044 223 VTSLTSKryILRFPALETLMLDDNRLSN-PScfaSLAGLRRLKKLSLDENRIIRIP 277
Cdd:COG4886   148 LTDLPEP--LGNLTNLKSLDLSNNQLTDlPE---ELGNLTNLKELDLSNNQITDLP 198
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 103-278 9.83e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.46  E-value: 9.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 103 SDLCTINVSGLKFSKAKENDFKHFHSVIYINASENLL----PLEAFHTFPALKELDLAFNGIkTIYVKYGDFKLLEFLDL 178
Cdd:PLN00113   69 SRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLsgpiPDDIFTTSSSLRYLNLSNNNF-TGSIPRGSIPNLETLDL 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 179 SFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNlavaeqeaSVTSLTSkryilrfpaLETLMLDDNRLSNpSCFASLA 258
Cdd:PLN00113  148 SNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPN--------SLTNLTS---------LEFLTLASNQLVG-QIPRELG 209

                         170       180
                  ....*....|....*....|.
gi 1802983044 259 GLRRLKKLSLDENRII-RIPY 278
Cdd:PLN00113  210 QMKSLKWIYLGYNNLSgEIPY 230
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 178-276 9.82e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 9.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 178 LSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPpNLAvaeqeasvtsltskryilRFPALETLMLDDNRLSnpsCFASL 257
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIE-NLE------------------FLTNLTHLYLQNNQIE---KIENL 64

                          90
                  ....*....|....*....
gi 1802983044 258 AGLRRLKKLSLDENRIIRI 276
Cdd:cd21340    65 ENLVNLKKLYLGGNRISVV 83
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
131-277 1.02e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 45.69  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 131 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSL 210
Cdd:COG4886     3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1802983044 211 PPNLAVAEQEASVTSLTS-----KRYILRFPALETLMLDDNRLSN-PscfASLAGLRRLKKLSLDENRIIRIP 277
Cdd:COG4886    83 SLLLLGLTDLGDLTNLTEldlsgNEELSNLTNLESLDLSGNQLTDlP---EELANLTNLKELDLSNNQLTDLP 152
LRR_8 pfam13855
Leucine rich repeat;
195-273 1.24e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 195 PHLRVLLLTGNGLTSLPPnlavaeqeasvtsltskRYILRFPALETLMLDDNRLS--NPSCFaslAGLRRLKKLSLDENR 272
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDD-----------------GAFKGLSNLKVLDLSNNLLTtlSPGAF---SGLPSLRYLDLSGNR 60


                  .
gi 1802983044 273 I 273
Cdd:pfam13855  61 L 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 142-273 3.23e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 43.50  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 142 EAFHTFPALKELDLAFN-----GIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGI----LPHLRVLLLTGNGLTSLPp 212
Cdd:cd00116   159 KALRANRDLKELNLANNgigdaGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAEtlasLKSLEVLNLGDNNLTDAG- 237

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802983044 213 nlAVAEQEASVTSLTSkryilrfpaLETLMLDDNRLSNPSCFASLAGLR---RLKKLSLDENRI 273
Cdd:cd00116   238 --AAALASALLSPNIS---------LLTLSLSCNDITDDGAKDLAEVLAekeSLLELDLRGNKF 290
LRR_8 pfam13855
Leucine rich repeat;
148-207 3.25e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 3.25e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802983044 148 PALKELDLAFNGIKTIYVKY-GDFKLLEFLDLSFNSLTV---EAICDLgilPHLRVLLLTGNGL 207
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTlspGAFSGL---PSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 141-277 6.97e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.70  E-value: 6.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 141 LEAFHTFPALKELDLAFNGIKTI----YVKYgdfklLEFLDLSF------NSLTVEAICDLGILPHLRVLLLTGNGLTSL 210
Cdd:cd21340    61 IENLENLVNLKKLYLGGNRISVVegleNLTN-----LEELHIENqrlppgEKLTFDPRSLAALSNSLRVLNISGNNIDSL 135

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1802983044 211 PPnLAVaeqeasvtsltskryilrFPALETLMLDDNRLSNPSCFA-SLAGLRRLKKLSLDENRIIRIP 277
Cdd:cd21340   136 EP-LAP------------------LRNLEQLDASNNQISDLEELLdLLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 141-282 2.59e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.15  E-value: 2.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 141 LEAFHTFPALKELDLAFNGIKTIyVKYGDFKLLEFLDLSFNSLTVeaICDLGILPHLRVLLLTGN------GLTS----- 209
Cdd:cd21340    17 IDNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEK--IENLENLVNLKKLYLGGNrisvveGLENltnle 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 210 --------LPPNLAVAEQEASVTSLTskryilrfPALETLMLDDNRLSNPSCfasLAGLRRLKKLSLDENRIIRIPYLQQ 281
Cdd:cd21340    94 elhienqrLPPGEKLTFDPRSLAALS--------NSLRVLNISGNNIDSLEP---LAPLRNLEQLDASNNQISDLEELLD 162


                  .
gi 1802983044 282 V 282
Cdd:cd21340   163 L 163
PLN03150 PLN03150
hypothetical protein; Provisional
 150-212 3.26e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.95  E-value: 3.26e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1802983044 150 LKELDLAFNGIK-TIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPP 212
Cdd:PLN03150  444 LQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
122-302 6.04e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.92  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 122 DFKHFHSVIYINASENLL-PLEAFHTFPALKELDLAFNGIKTIyVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVL 200
Cdd:COG4886   223 PLANLTNLETLDLSNNQLtDLPELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSL 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1802983044 201 LLTGNGLTSLPPNLavAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQ 280
Cdd:COG4886   302 LLLLLLLNLLELLI--LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379

                         170       180
                  ....*....|....*....|..
gi 1802983044 281 QVQLYDESVDWNGGRGSPHKEP 302
Cdd:COG4886   380 LTLALLLLTLLLLLLTTTAGVL 401
LRR_8 pfam13855
Leucine rich repeat;
139-183 7.15e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 7.15e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1802983044 139 LPLEAFHTFPALKELDLAFNGIKTIYvkYGDF---KLLEFLDLSFNSL 183
Cdd:pfam13855  16 LDDGAFKGLSNLKVLDLSNNLLTTLS--PGAFsglPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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