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fibrinogen beta chain isoform 8 preproprotein [Homo sapiens]
Fib_alpha and FReD domain-containing protein( domain architecture ID 10554875)
Fib_alpha and FReD domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Fib_alpha | pfam08702 | Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ... |
91-234 | 3.34e-67 | |||
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma). : Pssm-ID: 462570 Cd Length: 143 Bit Score: 208.16 E-value: 3.34e-67
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FReD super family | cl00085 | Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
238-359 | 1.68e-56 | |||
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation. The actual alignment was detected with superfamily member cd00087: Pssm-ID: 412152 [Multi-domain] Cd Length: 215 Bit Score: 183.60 E-value: 1.68e-56
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Name | Accession | Description | Interval | E-value | |||
Fib_alpha | pfam08702 | Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ... |
91-234 | 3.34e-67 | |||
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma). Pssm-ID: 462570 Cd Length: 143 Bit Score: 208.16 E-value: 3.34e-67
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FReD | cd00087 | Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
238-359 | 1.68e-56 | |||
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation. Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 183.60 E-value: 1.68e-56
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FBG | smart00186 | Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
237-360 | 4.27e-55 | |||
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous. Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 179.78 E-value: 4.27e-55
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Fibrinogen_C | pfam00147 | Fibrinogen beta and gamma chains, C-terminal globular domain; |
237-360 | 3.01e-54 | |||
Fibrinogen beta and gamma chains, C-terminal globular domain; Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 178.10 E-value: 3.01e-54
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GGGWT_bact | NF040941 | fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
241-282 | 1.12e-08 | |||
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV. Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 50.64 E-value: 1.12e-08
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Name | Accession | Description | Interval | E-value | |||
Fib_alpha | pfam08702 | Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ... |
91-234 | 3.34e-67 | |||
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma). Pssm-ID: 462570 Cd Length: 143 Bit Score: 208.16 E-value: 3.34e-67
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FReD | cd00087 | Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
238-359 | 1.68e-56 | |||
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation. Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 183.60 E-value: 1.68e-56
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FBG | smart00186 | Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
237-360 | 4.27e-55 | |||
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous. Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 179.78 E-value: 4.27e-55
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Fibrinogen_C | pfam00147 | Fibrinogen beta and gamma chains, C-terminal globular domain; |
237-360 | 3.01e-54 | |||
Fibrinogen beta and gamma chains, C-terminal globular domain; Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 178.10 E-value: 3.01e-54
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GGGWT_bact | NF040941 | fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
241-282 | 1.12e-08 | |||
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV. Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 50.64 E-value: 1.12e-08
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Blast search parameters | ||||
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