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Conserved domains on  [gi|1862723104|ref|NP_001371738|]
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microtubule-associated protein 4 isoform 108 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
882-911 1.07e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.07e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862723104  882 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
913-943 2.36e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 2.36e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862723104  913 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 943
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
859-880 1.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 1.31e-08
                           10        20
                   ....*....|....*....|..
gi 1862723104  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
721-995 1.34e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  721 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 800
Cdd:pfam05109  459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  801 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTE----NI 873
Cdd:pfam05109  530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSpqanTT 605
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  874 KHQPGGgrvqIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSE 953
Cdd:pfam05109  606 NHTLGG----TSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENI 681
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1862723104  954 APLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 995
Cdd:pfam05109  682 TQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PHA03247 super family cl33720
large tegument protein UL36; Provisional
575-852 6.37e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 6.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  575 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 653
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  654 CNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNK--ELPPSPEKKTKPIADAKAPEKRASPSKP--------ASAP 723
Cdd:PHA03247  2669 RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpEPAPHALVSATPLPPGPAAARQASPALPaapappavPAGP 2748
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  724 ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 803
Cdd:PHA03247  2749 ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL 2828
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723104  804 sgtAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKP----SSTTPRLSRLA 852
Cdd:PHA03247  2829 ---PPPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAakpaAPARPPVRRLA 2887
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
882-911 1.07e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.07e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862723104  882 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
913-943 2.36e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 2.36e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862723104  913 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 943
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
859-880 1.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 1.31e-08
                           10        20
                   ....*....|....*....|..
gi 1862723104  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
721-995 1.34e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  721 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 800
Cdd:pfam05109  459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  801 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTE----NI 873
Cdd:pfam05109  530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSpqanTT 605
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  874 KHQPGGgrvqIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSE 953
Cdd:pfam05109  606 NHTLGG----TSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENI 681
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1862723104  954 APLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 995
Cdd:pfam05109  682 TQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PRK13914 PRK13914
invasion associated endopeptidase;
656-872 1.44e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 42.48  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  656 SQPSELSSETSGIARPEEGRPVV-SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 734
Cdd:PRK13914   145 STPVAPTQEVKKETTTQQAAPAAeTKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWALSVKYGVSVQDI 224
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  735 VAKTTTAAAVASTGPS---SRSPSTLLPKkpTAIKTEGKPAEvkKMTAKSVPADLSrpKSTSTSSMKKTTTLSGTAPAAG 811
Cdd:PRK13914   225 MSWNNLSSSSIYVGQKlaiKQTANTATPK--AEVKTEAPAAE--KQAAPVVKENTN--TNTATTEKKETTTQQQTAPKAP 298
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723104  812 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP-RLSRLATNTSAPDLKNVRSKVGSTEN 872
Cdd:PRK13914   299 TEAAKPAPAPSTNTNANKTNTNTNTNTNNTNTSTPsKNTNTNTNSNTNTNSNTNANQGSSNN 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
575-852 6.37e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 6.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  575 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 653
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  654 CNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNK--ELPPSPEKKTKPIADAKAPEKRASPSKP--------ASAP 723
Cdd:PHA03247  2669 RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpEPAPHALVSATPLPPGPAAARQASPALPaapappavPAGP 2748
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  724 ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 803
Cdd:PHA03247  2749 ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL 2828
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723104  804 sgtAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKP----SSTTPRLSRLA 852
Cdd:PHA03247  2829 ---PPPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAakpaAPARPPVRRLA 2887
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
882-911 1.07e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.07e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862723104  882 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
913-943 2.36e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 2.36e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862723104  913 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 943
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
859-880 1.31e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 1.31e-08
                           10        20
                   ....*....|....*....|..
gi 1862723104  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
721-995 1.34e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  721 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 800
Cdd:pfam05109  459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  801 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTE----NI 873
Cdd:pfam05109  530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSpqanTT 605
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  874 KHQPGGgrvqIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSE 953
Cdd:pfam05109  606 NHTLGG----TSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENI 681
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1862723104  954 APLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 995
Cdd:pfam05109  682 TQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PRK13914 PRK13914
invasion associated endopeptidase;
656-872 1.44e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 42.48  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  656 SQPSELSSETSGIARPEEGRPVV-SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 734
Cdd:PRK13914   145 STPVAPTQEVKKETTTQQAAPAAeTKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWALSVKYGVSVQDI 224
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  735 VAKTTTAAAVASTGPS---SRSPSTLLPKkpTAIKTEGKPAEvkKMTAKSVPADLSrpKSTSTSSMKKTTTLSGTAPAAG 811
Cdd:PRK13914   225 MSWNNLSSSSIYVGQKlaiKQTANTATPK--AEVKTEAPAAE--KQAAPVVKENTN--TNTATTEKKETTTQQQTAPKAP 298
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723104  812 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP-RLSRLATNTSAPDLKNVRSKVGSTEN 872
Cdd:PRK13914   299 TEAAKPAPAPSTNTNANKTNTNTNTNTNNTNTSTPsKNTNTNTNSNTNTNSNTNANQGSSNN 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
647-858 1.52e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  647 KLGERKPCNSQPSELSSETSGIARPEEGRPVVS-GTGNDITTPPNKELPPSPEKKTKPIADAkapekrASPSKPASAPAS 725
Cdd:PHA03247  2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQRPRRRAARPTVGSLTSL------ADPPPPPPTPEP 2710
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  726 RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTtlsg 805
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---- 2784
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1862723104  806 tAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 858
Cdd:PHA03247  2785 -RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
692-841 6.27e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 6.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  692 ELPPSPEKKTKPI---ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSPStlLPKKPT 763
Cdd:PTZ00449   509 EPPEGPEASGLPPkapGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPE--FPKDPK 586
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  764 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--PFIDKKPTSA 839
Cdd:PTZ00449   587 HPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiIKSPKPPKSP 663

                   ..
gi 1862723104  840 KP 841
Cdd:PTZ00449   664 KP 665
PHA03247 PHA03247
large tegument protein UL36; Provisional
575-852 6.37e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 6.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  575 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 653
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  654 CNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNK--ELPPSPEKKTKPIADAKAPEKRASPSKP--------ASAP 723
Cdd:PHA03247  2669 RLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpEPAPHALVSATPLPPGPAAARQASPALPaapappavPAGP 2748
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  724 ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 803
Cdd:PHA03247  2749 ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL 2828
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723104  804 sgtAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKP----SSTTPRLSRLA 852
Cdd:PHA03247  2829 ---PPPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAakpaAPARPPVRRLA 2887
PHA03247 PHA03247
large tegument protein UL36; Provisional
653-847 8.85e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 8.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  653 PCNSQPSELSSETSGIARPEEGRPVVSGTGNDittPPNKELPPSPEKKTKPIADAKAPEKRASPSK-----PASAPASRS 727
Cdd:PHA03247  2575 PRPSEPAVTSRARRPDAPPQSARPRAPVDDRG---DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEpdphpPPTVPPPER 2651
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723104  728 GSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAiktegkPAEVKKMTAKSVPADLSR---PKSTSTSSMKKTTTLS 804
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA------RPTVGSLTSLADPPPPPPtpePAPHALVSATPLPPGP 2725
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1862723104  805 GTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP-----TSAKPSSTTPR 847
Cdd:PHA03247  2726 AAARQASPALPAAPAPPAVPAGPATPGGPARParpptTAGPPAPAPPA 2773
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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