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Conserved domains on  [gi|1876941705|ref|NP_001372480|]
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caprin-2 isoform 36 [Homo sapiens]

Protein Classification

Caprin-1_C domain-containing protein( domain architecture ID 12115383)

Caprin-1_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Caprin-1_C pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is ...
287-601 3.64e-158

Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteriztic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.


:

Pssm-ID: 463522 [Multi-domain]  Cd Length: 320  Bit Score: 456.56  E-value: 3.64e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 287 LQDLMTQIQGTCNFMQESVLDFDKPS-SAIPTSQPPSATP-----GSPVASKEQNLSSQSDFLQEPLQATSSPVTCSSNA 360
Cdd:pfam12287   1 LQDLMAQIQGTYNFMQDSMLDFDKPSdSAIVSAQPPSQSPdlsqmVCPPASPEQRLSQQSDVLQQPEQTQVSPVSPSSNA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 361 ClvttdqASSGSETEFMTSET--PEAAIPP---GKQPSSLASPNPPMAKGSE-QGFQSPPASSSSVTINTAPFQAMQTVF 434
Cdd:pfam12287  81 C------ASSGSEYQFHTSEPpqPEAIDPIqssMSLPSELAPPSPPLSPASQpQVFQSKPASSSGINVNAAPFQSMQTVF 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 435 NVNAPLPPRKEQEIKE-SPYSPGYNQSFTTASTQTPPQCQLPSIHVEQTVhsqeTANYHPDGTIQVSNGSLAFYPAQTNV 513
Cdd:pfam12287 155 NVNAPVPPRNEQELKEsSQYSSGYNQSFSSQSTQTVPQCQLPSEQLEQTV----VGAYHPDGTIQVSNGHLAFYPAQTNG 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 514 FPRPTQPFVNSRGSVRGCTRGGRLITNSYRSPGGYK-GFDTYRG-LPSISNGNYSQLQFQAREYSGAPYSQRDNFQQCYK 591
Cdd:pfam12287 231 FPRPPQPFYNSRGSPRGGPRGGRGLMNGYRGPNGFKgGFDGYRGpFPNTPNGGYGQLQFQARDYSGTPYSQRDGYQQNYK 310
                         330
                  ....*....|
gi 1876941705 592 RGGTSGGPRA 601
Cdd:pfam12287 311 RGGTQSGPRA 320
PTZ00121 super family cl31754
MAEBL; Provisional
7-236 6.41e-03

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 6.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705    7 KKTQLSKTESV-KESESLMEFAQPEIQPQEFLNR---RYMTEVDYSNKQGEEQPWEADYARKPNLPKR--WDMLTEPDGQ 80
Cdd:PTZ00121  1621 KAEELKKAEEEkKKVEQLKKKEAEEKKKAEELKKaeeENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKkaAEALKKEAEE 1700
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705   81 EKKQESFKSWEAS--------GKHQEVSKPAVSLEQRK--QDTSKLRSTLPEEQKKQEISKSKPSPSQWKQDTPKSKAGY 150
Cdd:PTZ00121  1701 AKKAEELKKKEAEekkkaeelKKAEEENKIKAEEAKKEaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  151 VQEEQKKQETPKlwpvqlQKEQDPKKQTPKSWTPSMQSEQNTTKSWTTPMCEEQDSKQPETPKS----WENNVESQKHSL 226
Cdd:PTZ00121  1781 IEEELDEEDEKR------RMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSknmqLEEADAFEKHKF 1854
                          250
                   ....*....|
gi 1876941705  227 TSQSQISPKS 236
Cdd:PTZ00121  1855 NKNNENGEDG 1864
 
Name Accession Description Interval E-value
Caprin-1_C pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is ...
287-601 3.64e-158

Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteriztic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.


Pssm-ID: 463522 [Multi-domain]  Cd Length: 320  Bit Score: 456.56  E-value: 3.64e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 287 LQDLMTQIQGTCNFMQESVLDFDKPS-SAIPTSQPPSATP-----GSPVASKEQNLSSQSDFLQEPLQATSSPVTCSSNA 360
Cdd:pfam12287   1 LQDLMAQIQGTYNFMQDSMLDFDKPSdSAIVSAQPPSQSPdlsqmVCPPASPEQRLSQQSDVLQQPEQTQVSPVSPSSNA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 361 ClvttdqASSGSETEFMTSET--PEAAIPP---GKQPSSLASPNPPMAKGSE-QGFQSPPASSSSVTINTAPFQAMQTVF 434
Cdd:pfam12287  81 C------ASSGSEYQFHTSEPpqPEAIDPIqssMSLPSELAPPSPPLSPASQpQVFQSKPASSSGINVNAAPFQSMQTVF 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 435 NVNAPLPPRKEQEIKE-SPYSPGYNQSFTTASTQTPPQCQLPSIHVEQTVhsqeTANYHPDGTIQVSNGSLAFYPAQTNV 513
Cdd:pfam12287 155 NVNAPVPPRNEQELKEsSQYSSGYNQSFSSQSTQTVPQCQLPSEQLEQTV----VGAYHPDGTIQVSNGHLAFYPAQTNG 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 514 FPRPTQPFVNSRGSVRGCTRGGRLITNSYRSPGGYK-GFDTYRG-LPSISNGNYSQLQFQAREYSGAPYSQRDNFQQCYK 591
Cdd:pfam12287 231 FPRPPQPFYNSRGSPRGGPRGGRGLMNGYRGPNGFKgGFDGYRGpFPNTPNGGYGQLQFQARDYSGTPYSQRDGYQQNYK 310
                         330
                  ....*....|
gi 1876941705 592 RGGTSGGPRA 601
Cdd:pfam12287 311 RGGTQSGPRA 320
PHA03247 PHA03247
large tegument protein UL36; Provisional
314-475 1.73e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  314 AIPTSQPPSATPGSPVASkeqnLSSQSDFLQEPLQATSSPVTCSSNACLVTTDQASSGSETEFMTSETPEAAIPPGKQPS 393
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVAS----LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  394 SLaSPNPPMAKGSEqgFQSPPASSSSVTINTAPfqAMQTVFNVNAPLPPRKEQEIKESPYSPgynQSFTTASTQTPPQCQ 473
Cdd:PHA03247  2849 SL-PLGGSVAPGGD--VRRRPPSRSPAAKPAAP--ARPPVRRLARPAVSRSTESFALPPDQP---ERPPQPQAPPPPQPQ 2920

                   ..
gi 1876941705  474 LP 475
Cdd:PHA03247  2921 PQ 2922
PTZ00121 PTZ00121
MAEBL; Provisional
7-236 6.41e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 6.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705    7 KKTQLSKTESV-KESESLMEFAQPEIQPQEFLNR---RYMTEVDYSNKQGEEQPWEADYARKPNLPKR--WDMLTEPDGQ 80
Cdd:PTZ00121  1621 KAEELKKAEEEkKKVEQLKKKEAEEKKKAEELKKaeeENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKkaAEALKKEAEE 1700
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705   81 EKKQESFKSWEAS--------GKHQEVSKPAVSLEQRK--QDTSKLRSTLPEEQKKQEISKSKPSPSQWKQDTPKSKAGY 150
Cdd:PTZ00121  1701 AKKAEELKKKEAEekkkaeelKKAEEENKIKAEEAKKEaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  151 VQEEQKKQETPKlwpvqlQKEQDPKKQTPKSWTPSMQSEQNTTKSWTTPMCEEQDSKQPETPKS----WENNVESQKHSL 226
Cdd:PTZ00121  1781 IEEELDEEDEKR------RMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSknmqLEEADAFEKHKF 1854
                          250
                   ....*....|
gi 1876941705  227 TSQSQISPKS 236
Cdd:PTZ00121  1855 NKNNENGEDG 1864
 
Name Accession Description Interval E-value
Caprin-1_C pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is ...
287-601 3.64e-158

Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteriztic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.


Pssm-ID: 463522 [Multi-domain]  Cd Length: 320  Bit Score: 456.56  E-value: 3.64e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 287 LQDLMTQIQGTCNFMQESVLDFDKPS-SAIPTSQPPSATP-----GSPVASKEQNLSSQSDFLQEPLQATSSPVTCSSNA 360
Cdd:pfam12287   1 LQDLMAQIQGTYNFMQDSMLDFDKPSdSAIVSAQPPSQSPdlsqmVCPPASPEQRLSQQSDVLQQPEQTQVSPVSPSSNA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 361 ClvttdqASSGSETEFMTSET--PEAAIPP---GKQPSSLASPNPPMAKGSE-QGFQSPPASSSSVTINTAPFQAMQTVF 434
Cdd:pfam12287  81 C------ASSGSEYQFHTSEPpqPEAIDPIqssMSLPSELAPPSPPLSPASQpQVFQSKPASSSGINVNAAPFQSMQTVF 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 435 NVNAPLPPRKEQEIKE-SPYSPGYNQSFTTASTQTPPQCQLPSIHVEQTVhsqeTANYHPDGTIQVSNGSLAFYPAQTNV 513
Cdd:pfam12287 155 NVNAPVPPRNEQELKEsSQYSSGYNQSFSSQSTQTVPQCQLPSEQLEQTV----VGAYHPDGTIQVSNGHLAFYPAQTNG 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 514 FPRPTQPFVNSRGSVRGCTRGGRLITNSYRSPGGYK-GFDTYRG-LPSISNGNYSQLQFQAREYSGAPYSQRDNFQQCYK 591
Cdd:pfam12287 231 FPRPPQPFYNSRGSPRGGPRGGRGLMNGYRGPNGFKgGFDGYRGpFPNTPNGGYGQLQFQARDYSGTPYSQRDGYQQNYK 310
                         330
                  ....*....|
gi 1876941705 592 RGGTSGGPRA 601
Cdd:pfam12287 311 RGGTQSGPRA 320
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
238-609 1.57e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 238 GVATASLIPNDQLLPRklNTEPKDVPKPVHQPVGSSSTLPKDPVLRKEKLQDlmtqiqgtcNFMQESVLDFDKPSSAIPT 317
Cdd:pfam05109 447 GLPSSTHVPTNLTAPA--STGPTVSTADVTSPTPAGTTSGASPVTPSPSPRD---------NGTESKAPDMTSPTSAVTT 515
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 318 SQPPSATPGSPVASKEQNLSSqsdflqePLQATSSPVTCssnaclVTTDQASSGSETEFMTSETPEAAIPP-GK-QPSSL 395
Cdd:pfam05109 516 PTPNATSPTPAVTTPTPNATS-------PTLGKTSPTSA------VTTPTPNATSPTPAVTTPTPNATIPTlGKtSPTSA 582
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 396 ASPNPPMAKGSEQGFQSPPA---------SSSSVTINTAPFQAMQTVFNVNAPLPPRKEQEIKESPYSPGYNQSFTTAST 466
Cdd:pfam05109 583 VTTPTPNATSPTVGETSPQAnttnhtlggTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDN 662
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 467 QTPPQCQLPSIHVE-----QTVHSQETANYHpdgtiqVSNGSLAFYPAQTNVFPRPTQPFVNSRGSVRGCTRGGRLI-TN 540
Cdd:pfam05109 663 STSHMPLLTSAHPTggeniTQVTPASTSTHH------VSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKnAT 736
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 541 SYRSPGGYKgfdtyRGLPSI-SNGNYSQLQFQAREYSGapYSQRDNFQQCYKRGGTSGGPRANSRANCFI 609
Cdd:pfam05109 737 SPQAPSGQK-----TAVPTVtSTGGKANSTTGGKHTTG--HGARTSTEPTTDYGGDSTTPRTRYNATTYL 799
PHA03247 PHA03247
large tegument protein UL36; Provisional
314-475 1.73e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  314 AIPTSQPPSATPGSPVASkeqnLSSQSDFLQEPLQATSSPVTCSSNACLVTTDQASSGSETEFMTSETPEAAIPPGKQPS 393
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVAS----LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  394 SLaSPNPPMAKGSEqgFQSPPASSSSVTINTAPfqAMQTVFNVNAPLPPRKEQEIKESPYSPgynQSFTTASTQTPPQCQ 473
Cdd:PHA03247  2849 SL-PLGGSVAPGGD--VRRRPPSRSPAAKPAAP--ARPPVRRLARPAVSRSTESFALPPDQP---ERPPQPQAPPPPQPQ 2920

                   ..
gi 1876941705  474 LP 475
Cdd:PHA03247  2921 PQ 2922
PTZ00121 PTZ00121
MAEBL; Provisional
7-236 6.41e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 6.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705    7 KKTQLSKTESV-KESESLMEFAQPEIQPQEFLNR---RYMTEVDYSNKQGEEQPWEADYARKPNLPKR--WDMLTEPDGQ 80
Cdd:PTZ00121  1621 KAEELKKAEEEkKKVEQLKKKEAEEKKKAEELKKaeeENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKkaAEALKKEAEE 1700
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705   81 EKKQESFKSWEAS--------GKHQEVSKPAVSLEQRK--QDTSKLRSTLPEEQKKQEISKSKPSPSQWKQDTPKSKAGY 150
Cdd:PTZ00121  1701 AKKAEELKKKEAEekkkaeelKKAEEENKIKAEEAKKEaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  151 VQEEQKKQETPKlwpvqlQKEQDPKKQTPKSWTPSMQSEQNTTKSWTTPMCEEQDSKQPETPKS----WENNVESQKHSL 226
Cdd:PTZ00121  1781 IEEELDEEDEKR------RMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSknmqLEEADAFEKHKF 1854
                          250
                   ....*....|
gi 1876941705  227 TSQSQISPKS 236
Cdd:PTZ00121  1855 NKNNENGEDG 1864
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
97-469 6.76e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 39.75  E-value: 6.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705  97 QEVSKPAVSLEQRKQDTSKLRSTLPEEQKKQEISKSKPSPSQwkqdTPKSKAGYVQEEQKKQETPKLWPVQLQKEQDPKK 176
Cdd:pfam03154 175 QAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQ----PPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQ 250
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 177 QTPKSWTPSMQSEQNTTK-SWTTPMCEEQDSKQpETPKSWENNVESQKHSLT---SQSQISPKSWGVATASLIPNDQLLP 252
Cdd:pfam03154 251 PMTQPPPPSQVSPQPLPQpSLHGQMPPMPHSLQ-TGPSHMQHPVPPQPFPLTpqsSQSQVPPGPSPAAPGQSQQRIHTPP 329
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 253 RKLNTEPKDVPK-----PVHQPVGSSSTLPKDPV--LRKEKLQDLMTQIQGTCNFMQESVLDFD---KPSSAIPTSQPPS 322
Cdd:pfam03154 330 SQSQLQSQQPPReqplpPAPLSMPHIKPPPTTPIpqLPNPQSHKHPPHLSGPSPFQMNSNLPPPpalKPLSSLSTHHPPS 409
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941705 323 ATPgspvasKEQNLSSQSDFLQEPlqATSSPVTCSSNACLVTTDQASSGSETEFMTSETPEAAIP--PGKQPSSLASPNP 400
Cdd:pfam03154 410 AHP------PPLQLMPQSQQLPPP--PAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPfvPGGPPPITPPSGP 481
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1876941705 401 PMAKGSEQGFQSPPASSSSVTINTAPFQAMQTVFNVNAPLPPRKEQEIKESPYSPGYNQSFTTASTQTP 469
Cdd:pfam03154 482 PTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTP 550
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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