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Concise Results
Standard Results
Full Results
janus kinase and microtubule-interacting protein 3 isoform n [Homo sapiens]
Protein Classification
SMC_prok_B and JAKMIP_CC3 domain-containing protein ( domain architecture ID 13531091 )
SMC_prok_B and JAKMIP_CC3 domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
357-553
6.97e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 267.52
E-value: 6.97e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 357 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 435
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 436 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 515
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1973459236 516 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 553
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-547
4.71e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 66.50
E-value: 4.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL TLVIQADKIKAA E 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL LEAEAELAEAEE E 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 186 IRSVYHLHQ E EITRI -- KKECER E IRRL E QQ L D E KDA R RFQLKIAELS A IIRKL E DRNAL --- L S E ERN E LLKRVR E A E S 260
Cdd:COG1196 381 LEELAEELL E ALRAA ae LAAQLE E LEEA E EA L L E RLE R LEEELEELEE A LAELE E EEEEE eea L E E AAE E EAELEE E E E A 460
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 261 QYKP L LDKNKRLSRKNED L SHA L R - RM E NKLKFVTQENI E MRQRAGIIRRPSS L NDLDQSQDERE V DF L KLQIVEQQNLI 339
Cdd:COG1196 461 LLEL L AELLEEAALLEAA L AEL L E e LA E AAARLLLLLEA E ADYEGFLEGVKAA L LLAGLRGLAGA V AV L IGVEAAYEAAL 540
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 340 DELSKTLETAGY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTDQTPCTPDDDL 417
Cdd:COG1196 541 EAALAAALQNIV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LREADARYYVLGD 620
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 418 EEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE Q gqdmkw IE E 497
Cdd:COG1196 621 TLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE E ------ EL E 694
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1973459236 498 KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 547
Cdd:COG1196 695 LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
423-749
6.02e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 56.48
E-value: 6.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 K E ET EL RFRQ L TMEYQA L QRAYAL L QEQVG - GTLDA E REVKTREQ L Q AE VQRAQARI E D LE KA L A E - Q GQDMKWIE E KQA 500
Cdd:COG1196 220 E E LK EL EAEL L LLKLRE L EAELEE L EAELE e LEAEL E ELEAELAE L E AE LEELRLEL E E LE LE L E E a Q AEEYELLA E LAR 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 501 L YRRNQE L V E KIKQM E TEEAR L RH E VQDARDQN E L LE FRIL ELEE RE rkspaisfhhtpfvdgksplqvyceaegvtdiv 580
Cdd:COG1196 300 L EQDIAR L E E RRREL E ERLEE L EE E LAELEEEL E E LE EELE ELEE EL --------------------------------- 346
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 581 v A E LMKK L D ilgdnanltn E EQVVVIQ A RTV L TL AE KW L QQI EE TEAA L QRKMVDLESEKELFSK Q KGY L D E ELDYRKQA 660
Cdd:COG1196 347 - E E AEEE L E ---------- E AEAELAE A EEA L LE AE AE L AEA EE ELEE L AEELLEALRAAAELAA Q LEE L E E AEEALLER 415
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 661 L DQANKHIL ELE AM L YDALQQ E AGAKV A ELLSE EE REK L KVAV E Q w KRQVMS EL R E RD A QILRERM ELL QLAQQRIKE L E 740
Cdd:COG1196 416 L ERLEEELE ELE EA L AELEEE E EEEEE A LEEAA EE EAE L EEEE E A - LLELLA EL L E EA A LLEAALA ELL EELAEAAAR L L 494
....*....
gi 1973459236 741 ERI EA QKRQ 749
Cdd:COG1196 495 LLL EA EADY 503
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
357-553
6.97e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 267.52
E-value: 6.97e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 357 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 435
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 436 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 515
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1973459236 516 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 553
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-547
4.71e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 66.50
E-value: 4.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL TLVIQADKIKAA E 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL LEAEAELAEAEE E 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 186 IRSVYHLHQ E EITRI -- KKECER E IRRL E QQ L D E KDA R RFQLKIAELS A IIRKL E DRNAL --- L S E ERN E LLKRVR E A E S 260
Cdd:COG1196 381 LEELAEELL E ALRAA ae LAAQLE E LEEA E EA L L E RLE R LEEELEELEE A LAELE E EEEEE eea L E E AAE E EAELEE E E E A 460
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 261 QYKP L LDKNKRLSRKNED L SHA L R - RM E NKLKFVTQENI E MRQRAGIIRRPSS L NDLDQSQDERE V DF L KLQIVEQQNLI 339
Cdd:COG1196 461 LLEL L AELLEEAALLEAA L AEL L E e LA E AAARLLLLLEA E ADYEGFLEGVKAA L LLAGLRGLAGA V AV L IGVEAAYEAAL 540
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 340 DELSKTLETAGY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTDQTPCTPDDDL 417
Cdd:COG1196 541 EAALAAALQNIV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LREADARYYVLGD 620
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 418 EEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE Q gqdmkw IE E 497
Cdd:COG1196 621 TLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE E ------ EL E 694
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1973459236 498 KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 547
Cdd:COG1196 695 LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-746
7.12e-11
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 65.85
E-value: 7.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAV ----- L L T EL KTKLH E EKMKELQAVR E TL - L RQH 98
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAEL qelee K L E EL RLEVS E LEEEIEELQK E LY a L ANE 296
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 99 EAE L LRVIK I KDNENQR L QAL L SA L RDGGP E - KV K TVL L S E AKE E AKKGF E VE K VKMQQEIS EL KGAKRQV EE ALTLVIQ 177
Cdd:TIGR02168 297 ISR L EQQKQ I LRERLAN L ERQ L EE L EAQLE E l ES K LDE L A E ELA E LEEKL E EL K EELESLEA EL EELEAEL EE LESRLEE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 178 ADK i KAAEI RS VYHLHQEE I TRIKK E C ER ----------------- EI RR L EQQ L D E KDARRF Q LKIA EL SAIIRK L EDR 240
Cdd:TIGR02168 377 LEE - QLETL RS KVAQLELQ I ASLNN E I ER learlerledrrerlqq EI EE L LKK L E E AELKEL Q AELE EL EEELEE L QEE 455
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 241 NAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRKNED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQ 320
Cdd:TIGR02168 456 LER L E E ALE EL REELE EAE QALDAAERELAQ L QARLDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EG 534
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 321 D E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVS 400
Cdd:TIGR02168 535 Y E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLG 602
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 401 YQT D RTDQT P ------------ CTPD DDL EEGMA - KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr 464
Cdd:TIGR02168 603 VAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- 679
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 465 E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi EE KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL 541
Cdd:TIGR02168 680 E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- EE LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT 757
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 542 ELE ERERKS paisfhhtpfvdg KSP L QVYC E AEGVTDIVVA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQ 621
Cdd:TIGR02168 758 ELE AEIEEL ------------- EER L EEAE E ELAEAEAEIE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAAN 821
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 622 IE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDYRKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KV 701
Cdd:TIGR02168 822 LR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIESLAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SE 901
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 1973459236 702 AVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRIKELEERIEAQ 746
Cdd:TIGR02168 902 ELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGLEVRIDNLQER 944
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
423-749
6.02e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 56.48
E-value: 6.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 K E ET EL RFRQ L TMEYQA L QRAYAL L QEQVG - GTLDA E REVKTREQ L Q AE VQRAQARI E D LE KA L A E - Q GQDMKWIE E KQA 500
Cdd:COG1196 220 E E LK EL EAEL L LLKLRE L EAELEE L EAELE e LEAEL E ELEAELAE L E AE LEELRLEL E E LE LE L E E a Q AEEYELLA E LAR 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 501 L YRRNQE L V E KIKQM E TEEAR L RH E VQDARDQN E L LE FRIL ELEE RE rkspaisfhhtpfvdgksplqvyceaegvtdiv 580
Cdd:COG1196 300 L EQDIAR L E E RRREL E ERLEE L EE E LAELEEEL E E LE EELE ELEE EL --------------------------------- 346
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 581 v A E LMKK L D ilgdnanltn E EQVVVIQ A RTV L TL AE KW L QQI EE TEAA L QRKMVDLESEKELFSK Q KGY L D E ELDYRKQA 660
Cdd:COG1196 347 - E E AEEE L E ---------- E AEAELAE A EEA L LE AE AE L AEA EE ELEE L AEELLEALRAAAELAA Q LEE L E E AEEALLER 415
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 661 L DQANKHIL ELE AM L YDALQQ E AGAKV A ELLSE EE REK L KVAV E Q w KRQVMS EL R E RD A QILRERM ELL QLAQQRIKE L E 740
Cdd:COG1196 416 L ERLEEELE ELE EA L AELEEE E EEEEE A LEEAA EE EAE L EEEE E A - LLELLA EL L E EA A LLEAALA ELL EELAEAAAR L L 494
....*....
gi 1973459236 741 ERI EA QKRQ 749
Cdd:COG1196 495 LLL EA EADY 503
PTZ00121
PTZ00121 MAEBL; Provisional
41-287
5.01e-04
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 43.98
E-value: 5.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 41 Q EK S K VS --- K V E RE KN QE LR QVR E HEQHKT A VLLTEL K TKLH E E KMK ELQ A vretll RQH E AELLRVIKI K DN E NQRLQ 117
Cdd:PTZ00121 1561 E EK K K AE eak K A E ED KN MA LR KAE E AKKAEE A RIEEVM K LYEE E K KMK AEE A ------ KKA E EAKIKAEEL K KA E EEKKK 1634
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 118 al LSA L RDGGP E KV K TV llseak EE A KK GF E VE K V K MQQ E ISELKGA K RQV EEA LTL vi QA D KI KAAE IRSVYHLHQEEI 197
Cdd:PTZ00121 1635 -- VEQ L KKKEA E EK K KA ------ EE L KK AE E EN K I K AAE E AKKAEED K KKA EEA KKA -- EE D EK KAAE ALKKEAEEAKKA 1704
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 198 TRI KK ECER E IRRL E QQLDEKDARRFQLKI A ELS A IIR K LEDRN A LLS E - E RNELLKRVR E A E SQYKPLLDKNKRLSRKN 276
Cdd:PTZ00121 1705 EEL KK KEAE E KKKA E ELKKAEEENKIKAEE A KKE A EED K KKAEE A KKD E e E KKKIAHLKK E E E KKAEEIRKEKEAVIEEE 1784
250
....*....|.
gi 1973459236 277 E D LSHAL RRME 287
Cdd:PTZ00121 1785 L D EEDEK RRME 1795
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
424-548
2.71e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 424 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 499
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1973459236 500 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 548
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
423-747
3.07e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 41.20
E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 502
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 503 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 582
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 583 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 662
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 663 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 742
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1973459236 743 IE A QK 747
Cdd:TIGR02168 508 VK A LL 512
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
357-553
6.97e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 267.52
E-value: 6.97e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 357 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 435
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 436 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 515
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1973459236 516 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 553
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-547
4.71e-11
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 66.50
E-value: 4.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL TLVIQADKIKAA E 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL LEAEAELAEAEE E 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 186 IRSVYHLHQ E EITRI -- KKECER E IRRL E QQ L D E KDA R RFQLKIAELS A IIRKL E DRNAL --- L S E ERN E LLKRVR E A E S 260
Cdd:COG1196 381 LEELAEELL E ALRAA ae LAAQLE E LEEA E EA L L E RLE R LEEELEELEE A LAELE E EEEEE eea L E E AAE E EAELEE E E E A 460
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 261 QYKP L LDKNKRLSRKNED L SHA L R - RM E NKLKFVTQENI E MRQRAGIIRRPSS L NDLDQSQDERE V DF L KLQIVEQQNLI 339
Cdd:COG1196 461 LLEL L AELLEEAALLEAA L AEL L E e LA E AAARLLLLLEA E ADYEGFLEGVKAA L LLAGLRGLAGA V AV L IGVEAAYEAAL 540
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 340 DELSKTLETAGY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTDQTPCTPDDDL 417
Cdd:COG1196 541 EAALAAALQNIV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LREADARYYVLGD 620
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 418 EEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE Q gqdmkw IE E 497
Cdd:COG1196 621 TLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE E ------ EL E 694
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1973459236 498 KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 547
Cdd:COG1196 695 LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-746
7.12e-11
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 65.85
E-value: 7.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAV ----- L L T EL KTKLH E EKMKELQAVR E TL - L RQH 98
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAEL qelee K L E EL RLEVS E LEEEIEELQK E LY a L ANE 296
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 99 EAE L LRVIK I KDNENQR L QAL L SA L RDGGP E - KV K TVL L S E AKE E AKKGF E VE K VKMQQEIS EL KGAKRQV EE ALTLVIQ 177
Cdd:TIGR02168 297 ISR L EQQKQ I LRERLAN L ERQ L EE L EAQLE E l ES K LDE L A E ELA E LEEKL E EL K EELESLEA EL EELEAEL EE LESRLEE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 178 ADK i KAAEI RS VYHLHQEE I TRIKK E C ER ----------------- EI RR L EQQ L D E KDARRF Q LKIA EL SAIIRK L EDR 240
Cdd:TIGR02168 377 LEE - QLETL RS KVAQLELQ I ASLNN E I ER learlerledrrerlqq EI EE L LKK L E E AELKEL Q AELE EL EEELEE L QEE 455
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 241 NAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRKNED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQ 320
Cdd:TIGR02168 456 LER L E E ALE EL REELE EAE QALDAAERELAQ L QARLDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EG 534
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 321 D E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVS 400
Cdd:TIGR02168 535 Y E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLG 602
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 401 YQT D RTDQT P ------------ CTPD DDL EEGMA - KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr 464
Cdd:TIGR02168 603 VAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- 679
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 465 E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi EE KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL 541
Cdd:TIGR02168 680 E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- EE LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT 757
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 542 ELE ERERKS paisfhhtpfvdg KSP L QVYC E AEGVTDIVVA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQ 621
Cdd:TIGR02168 758 ELE AEIEEL ------------- EER L EEAE E ELAEAEAEIE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAAN 821
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 622 IE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDYRKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KV 701
Cdd:TIGR02168 822 LR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIESLAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SE 901
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 1973459236 702 AVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRIKELEERIEAQ 746
Cdd:TIGR02168 902 ELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGLEVRIDNLQER 944
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-547
1.95e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 58.02
E-value: 1.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 E D L R A K L TDIQI EL QQEKSKV skve R E KNQ EL RQVREH E QHKT A V L LTELKTKLHE E KMKELQAV R ETL L RQHE AEL LRV 105
Cdd:COG1196 256 E E L E A E L AELEA EL EELRLEL ---- E E LEL EL EEAQAE E YELL A E L ARLEQDIARL E ERRRELEE R LEE L EEEL AEL EEE 331
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDN E NQR L QAL L SALR dggpekvktvlls E AK EEA KKGFEVEKVKMQQEIS EL KG A KRQV EE ALTLVIQ A DKIK A AE 185
Cdd:COG1196 332 LEELEE E LEE L EEE L EEAE ------------- E EL EEA EAELAEAEEALLEAEA EL AE A EEEL EE LAEELLE A LRAA A EL 398
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 186 IRSVYH L HQE E ITRIKKECER E IRRL E QQLDEKDARRFQLKIA E LSAIIRKL E DRNALLS E ERN ELL KRVR E AESQYKPL 265
Cdd:COG1196 399 AAQLEE L EEA E EALLERLERL E EELE E LEEALAELEEEEEEEE E ALEEAAEE E AELEEEE E ALL ELL AELL E EAALLEAA 478
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 266 L DKNKRLSRKNEDLSHA L RRM E NKLKFVTQENIEMRQR AG IIRRPSSLND L DQSQDER E VDFLK - L QIVE Q QNLIDELSK 344
Cdd:COG1196 479 L AELLEELAEAAARLLL L LEA E ADYEGFLEGVKAALLL AG LRGLAGAVAV L IGVEAAY E AALEA a L AAAL Q NIVVEDDEV 558
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 345 TLETAG Y V K S - VLE R DKL L RFR K Q R KKM A KLPKPVVVETFFGY D EE AS LESDGSSVS Y QTDR T DQ - TPCTPDDDLEEGMA 422
Cdd:COG1196 559 AAAAIE Y L K A a KAG R ATF L PLD K I R ARA A LAAALARGAIGAAV D LV AS DLREADARY Y VLGD T LL g RTLVAARLEAALRR 638
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 KEETEL R F R QL T M E YQALQRAYA L LQEQVGGT L D A ER E VKTREQLQ AE VQRAQARIEDLEKALA E QGQDMKWIE E KQA L Y 502
Cdd:COG1196 639 AVTLAG R L R EV T L E GEGGSAGGS L TGGSRREL L A A LL E AEAELEEL AE RLAEEELELEEALLAE E EEERELAEA E EER L E 718
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1973459236 503 RRNQ E LVEKIKQMETE E AR L RHEVQDARDQN E LLEFRIL E LEER E 547
Cdd:COG1196 719 EELE E EALEEQLEAER E EL L EELLEEEELLE E EALEELP E PPDL E 763
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
423-749
6.02e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 56.48
E-value: 6.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 K E ET EL RFRQ L TMEYQA L QRAYAL L QEQVG - GTLDA E REVKTREQ L Q AE VQRAQARI E D LE KA L A E - Q GQDMKWIE E KQA 500
Cdd:COG1196 220 E E LK EL EAEL L LLKLRE L EAELEE L EAELE e LEAEL E ELEAELAE L E AE LEELRLEL E E LE LE L E E a Q AEEYELLA E LAR 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 501 L YRRNQE L V E KIKQM E TEEAR L RH E VQDARDQN E L LE FRIL ELEE RE rkspaisfhhtpfvdgksplqvyceaegvtdiv 580
Cdd:COG1196 300 L EQDIAR L E E RRREL E ERLEE L EE E LAELEEEL E E LE EELE ELEE EL --------------------------------- 346
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 581 v A E LMKK L D ilgdnanltn E EQVVVIQ A RTV L TL AE KW L QQI EE TEAA L QRKMVDLESEKELFSK Q KGY L D E ELDYRKQA 660
Cdd:COG1196 347 - E E AEEE L E ---------- E AEAELAE A EEA L LE AE AE L AEA EE ELEE L AEELLEALRAAAELAA Q LEE L E E AEEALLER 415
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 661 L DQANKHIL ELE AM L YDALQQ E AGAKV A ELLSE EE REK L KVAV E Q w KRQVMS EL R E RD A QILRERM ELL QLAQQRIKE L E 740
Cdd:COG1196 416 L ERLEEELE ELE EA L AELEEE E EEEEE A LEEAA EE EAE L EEEE E A - LLELLA EL L E EA A LLEAALA ELL EELAEAAAR L L 494
....*....
gi 1973459236 741 ERI EA QKRQ 749
Cdd:COG1196 495 LLL EA EADY 503
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
158-751
1.25e-07
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 55.33
E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 158 ISE L KGAKRQV E EALT L VIQADKIK A AEIRSVYHLHQE E ITRIKK --- E C E R E IRR LE QQ L D E KD A R rfqlk IA EL SAII 234
Cdd:COG1196 202 LEP L ERQAEKA E RYRE L KEELKELE A ELLLLKLRELEA E LEELEA ele E L E A E LEE LE AE L A E LE A E ----- LE EL RLEL 276
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 235 RK LE DRNALLSE E RN ELL KRVREA E SQYKP L LDKNKR L SRKN E D L SHA L RRM E NK L KFVTQ E NI E MRQRAGIIRRP ---- 310
Cdd:COG1196 277 EE LE LELEEAQA E EY ELL AELARL E QDIAR L EERRRE L EERL E E L EEE L AEL E EE L EELEE E LE E LEEELEEAEEE leea 356
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 311 - SS L NDLDQSQD E R E VDFLKLQIVEQQNLIDE L SKTLET A GYVKSVL E RDKLLRFRKQ R KKMAK lpkpvvvetffgy D E E 389
Cdd:COG1196 357 e AE L AEAEEALL E A E AELAEAEEELEELAEEL L EALRAA A ELAAQLE E LEEAEEALLE R LERLE ------------- E E L 423
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 390 AS LE SDGSSVSYQTDRTDQT pctpdd DL E EGMAKE E T E LRFRQ L TMEYQA L QRAY ALL QEQVGGT L DAER E VKT R EQ L QA 469
Cdd:COG1196 424 EE LE EALAELEEEEEEEEEA ------ LE E AAEEEA E L E EEEEA L LELLAE L LEEA ALL EAALAEL L EELA E AAA R LL L LL 497
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 470 E VQR - AQARI E DLEK AL AEQ G QDMKWIEE kq A LYRRNQELV E KIKQMETEE A RLRHE V Q D ARDQNELL E FRILELEE R ER 548
Cdd:COG1196 498 E AEA d YEGFL E GVKA AL LLA G LRGLAGAV -- A VLIGVEAAY E AALEAALAA A LQNIV V E D DEVAAAAI E YLKAAKAG R AT 575
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 549 KS P AISFHHTPFVDGKSPLQVYCE A EGVTDIVVA E LMKKLDI LGD NA nltneeq VVVIQARTV L TL A EKWLQQIEETEAA 628
Cdd:COG1196 576 FL P LDKIRARAALAAALARGAIGA A VDLVASDLR E ADARYYV LGD TL ------- LGRTLVAAR L EA A LRRAVTLAGRLRE 648
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 629 LQRKMVDLESEKE L FSKQKGY L DEE L DYRKQA L DQANKHIL E L E AM L YD AL QQ E AGAKVAELLS EEER EKLKVAV E Q w KR 708
Cdd:COG1196 649 VTLEGEGGSAGGS L TGGSRRE L LAA L LEAEAE L EELAERLA E E E LE L EE AL LA E EEEERELAEA EEER LEEELEE E A - LE 727
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 1973459236 709 QVMSEL RE RDAQI L R E RM ELL QLAQQRIKELEERI E AQK R QIK 751
Cdd:COG1196 728 EQLEAE RE ELLEE L L E EE ELL EEEALEELPEPPDL E ELE R ELE 770
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
50-751
4.83e-07
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 53.53
E-value: 4.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 50 E R EK NQ E LRQVR E HEQHKTAV LL T EL KT K LHEEKMK E LQA V R E TL l RQH EAE LLRVIKIKDNENQR L QALLSA L RDGGP E 129
Cdd:TIGR02169 252 E L EK LT E EISEL E KRLEEIEQ LL E EL NK K IKDLGEE E QLR V K E KI - GEL EAE IASLERSIAEKERE L EDAEER L AKLEA E 330
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 130 KV K TVLLS E AK E EAKKGFEVEKV K MQQ E IS ELK gakr QVE E A L TLVIQADKIKA AE I R SVYHLHQ E EITRI K K E CEREI R 209
Cdd:TIGR02169 331 ID K LLAEI E EL E REIEEERKRRD K LTE E YA ELK ---- EEL E D L RAELEEVDKEF AE T R DELKDYR E KLEKL K R E INELK R 406
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 210 R L EQQLD E K da R R FQLKI A E L S A I I RKL E DRNAL L S EE RNELLKRVREA E SQYKP L LDKNKRLSRKNE DL SHALR R M E NK 289
Cdd:TIGR02169 407 E L DRLQE E L -- Q R LSEEL A D L N A A I AGI E AKINE L E EE KEDKALEIKKQ E WKLEQ L AADLSKYEQELY DL KEEYD R V E KE 484
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 290 L KFVTQ E NI E MRQR A GIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTL E T A G ------- Y V KSVLERDKLL 362
Cdd:TIGR02169 485 L SKLQR E LA E AEAQ A RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI E V A A gnrlnnv V V EDDAVAKEAI 564
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 363 RFR K Q RK ---------- KM AKLPKPVVVETFF G YDEE A ---- SLESDGSSVSYQTDRTDQTP ctpd D D L E EG mak EETEL 428
Cdd:TIGR02169 565 ELL K R RK agratflpln KM RDERRDLSILSED G VIGF A vdlv EFDPKYEPAFKYVFGDTLVV ---- E D I E AA --- RRLMG 637
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 429 RF R QL T M E YQALQRAY A L lqeq V GG TLDAEREVKTREQLQ AE V QR AQA R I E D L EKA L AEQGQDMKW IE ek QA L YRRN QEL 508
Cdd:TIGR02169 638 KY R MV T L E GELFEKSG A M ---- T GG SRAPRGGILFSRSEP AE L QR LRE R L E G L KRE L SSLQSELRR IE -- NR L DELS QEL 711
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 509 VEKIKQMETE E ARLRHEV Q DARDQN E L LE FRILE L EER E RKSPAI sfhhtpfvdg KS P L Q vyc E A E GVTDIVVAE L M K KL 588
Cdd:TIGR02169 712 SDASRKIGEI E KEIEQLE Q EEEKLK E R LE ELEED L SSL E QEIENV ---------- KS E L K --- E L E ARIEELEED L H K LE 778
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 589 DI L G D NANLTNEEQVVV IQA R tv L TLA E KWLQQ IE ETEAALQR K MVD L ES EKE LFS K QKGY L D E ELDYR K QALDQAN K H I 668
Cdd:TIGR02169 779 EA L N D LEARLSHSRIPE IQA E -- L SKL E EEVSR IE ARLREIEQ K LNR L TL EKE YLE K EIQE L Q E QRIDL K EQIKSIE K E I 856
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 669 LE L EAMLYDALQQEAGAKV A ELLS E EEREK LK VAVEQWKR Q v MS EL RER daqi LR E RMELLQLAQQ R IK EL EERI EA QKR 748
Cdd:TIGR02169 857 EN L NGKKEELEEELEELEA A LRDL E SRLGD LK KERDELEA Q - LR EL ERK ---- IE E LEAQIEKKRK R LS EL KAKL EA LEE 931
...
gi 1973459236 749 QIK 751
Cdd:TIGR02169 932 ELS 934
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
209-771
6.01e-07
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 53.02
E-value: 6.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 209 R R L EQQ L D E KD A RRFQ LK IA EL S A IIRK LE DRNAL L SE E RN EL LKRVR E A E SQYKP L LDKNKR L SRKN E DLSHALRRMEN 288
Cdd:COG1196 216 R E L KEE L K E LE A ELLL LK LR EL E A ELEE LE AELEE L EA E LE EL EAELA E L E AELEE L RLELEE L ELEL E EAQAEEYELLA 295
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 289 K L kfvtq ENI E MRQRAGII RR PSSLND L DQSQD E REV df L KLQIV E QQNLID EL SKT LE T A gyvksvlerdk LLRFRKQR 368
Cdd:COG1196 296 E L ----- ARL E QDIARLEE RR RELEER L EELEE E LAE -- L EEELE E LEEELE EL EEE LE E A ----------- EEELEEAE 357
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 369 KKM A KL pkpvvvetffgyd EEA S LE SDGSSVSYQTDRTDQT pctp DDD LE EGM A KE E TELRFRQ L TMEYQ AL QRAYAL L Q 448
Cdd:COG1196 358 AEL A EA ------------- EEA L LE AEAELAEAEEELEELA ---- EEL LE ALR A AA E LAAQLEE L EEAEE AL LERLER L E 420
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 449 E QVGGTLD A ER E V kt R E QLQA E VQRAQARI E DLEKALA E QGQDMKWIE E KQALYRRNQELVEKIKQMET E E A RLRHEVQD 528
Cdd:COG1196 421 E ELEELEE A LA E L -- E E EEEE E EEALEEAA E EEAELEE E EEALLELLA E LLEEAALLEAALAELLEELA E A A ARLLLLLE 498
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 529 A RDQN E LLEFRILELEERERKSPAISFHHTPFVDGKSPLQVY - CEAEGVTDIV V A E LMKKLDILGDNANLTNEEQVVVIQ 607
Cdd:COG1196 499 A EADY E GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL e AALAAALQNI V V E DDEVAAAAIEYLKAAKAGRATFLP 578
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 608 ARTVLTL A EKWLQQIEETEA A LQRKMVDLES E KELFSKQK G YLDEELDYRKQA L DQ A NKHILE L EAM L YDALQQEA G AKV 687
Cdd:COG1196 579 LDKIRAR A ALAAALARGAIG A AVDLVASDLR E ADARYYVL G DTLLGRTLVAAR L EA A LRRAVT L AGR L REVTLEGE G GSA 658
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 688 AEL L SEEE R EK L KV A VEQWKRQVMSELRERDAQI L RERME LL QLAQQRIKEL E ERI E AQKRQIK E LEEKFLFLFLFFS L A 767
Cdd:COG1196 659 GGS L TGGS R RE L LA A LLEAEAELEELAERLAEEE L ELEEA LL AEEEEERELA E AEE E RLEEELE E EALEEQLEAEREE L L 738
....
gi 1973459236 768 FI L W 771
Cdd:COG1196 739 EE L L 742
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-523
1.31e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 45.70
E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 E DLRAK L TDIQI EL QQEKSKVSKV E R E KNQELRQVR E HEQHKTAV L LTELKTKLHE E KMK E LQAVRETL L RQH E A EL LRV 105
Cdd:COG1196 347 E EAEEE L EEAEA EL AEAEEALLEA E A E LAEAEEELE E LAEELLEA L RAAAELAAQL E ELE E AEEALLER L ERL E E EL EEL 426
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDNENQRLQALLS AL RDGGP E KVKTVLLS EA KE E AKKGFEV E KVKMQQEIS EL KGAKRQVEEA L T L VIQ A DKIKAAE 185
Cdd:COG1196 427 EEALAELEEEEEEEEE AL EEAAE E EAELEEEE EA LL E LLAELLE E AALLEAALA EL LEELAEAAAR L L L LLE A EADYEGF 506
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 186 IRS V YHLHQEEIT R IKKECEREIRRL E QQLDEKDA rrfqlki A E L S A IIRKLEDRNALLSEERN E L LK RVREAESQYK PL 265
Cdd:COG1196 507 LEG V KAALLLAGL R GLAGAVAVLIGV E AAYEAALE ------- A A L A A ALQNIVVEDDEVAAAAI E Y LK AAKAGRATFL PL 579
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 266 LDKNK R LSRKNEDLSH A LRRMENKLKFVTQ E NIEMRQRA G IIRRPSS L NDLDQSQDE R EVDF L KLQIV E QQNLIDEL S KT 345
Cdd:COG1196 580 DKIRA R AALAAALARG A IGAAVDLVASDLR E ADARYYVL G DTLLGRT L VAARLEAAL R RAVT L AGRLR E VTLEGEGG S AG 659
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 346 LETA G YVKSV L ERDK L LRFRKQRKKMAK L pkpvvvetffg YD EE AS LE SDGSSVSYQTDRTDQ tpctp DDDLEEGMAK EE 425
Cdd:COG1196 660 GSLT G GSRRE L LAAL L EAEAELEELAER L ----------- AE EE LE LE EALLAEEEEERELAE ----- AEEERLEEEL EE 723
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 426 TE L RFRQLTMEYQA L QRAYALLQEQVGGT L DAER E VKTR E Q L QA E VQ R AQAR IE D L EK -- A LA eqgqdmkw IEE KQA L YR 503
Cdd:COG1196 724 EA L EEQLEAEREEL L EELLEEEELLEEEA L EELP E PPDL E E L ER E LE R LERE IE A L GP vn L LA -------- IEE YEE L EE 795
490 500
....*....|....*....|
gi 1973459236 504 R NQE L V E KIKQM E TEEAR L R 523
Cdd:COG1196 796 R YDF L S E QREDL E EARET L E 815
PTZ00121
PTZ00121 MAEBL; Provisional
41-287
5.01e-04
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 43.98
E-value: 5.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 41 Q EK S K VS --- K V E RE KN QE LR QVR E HEQHKT A VLLTEL K TKLH E E KMK ELQ A vretll RQH E AELLRVIKI K DN E NQRLQ 117
Cdd:PTZ00121 1561 E EK K K AE eak K A E ED KN MA LR KAE E AKKAEE A RIEEVM K LYEE E K KMK AEE A ------ KKA E EAKIKAEEL K KA E EEKKK 1634
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 118 al LSA L RDGGP E KV K TV llseak EE A KK GF E VE K V K MQQ E ISELKGA K RQV EEA LTL vi QA D KI KAAE IRSVYHLHQEEI 197
Cdd:PTZ00121 1635 -- VEQ L KKKEA E EK K KA ------ EE L KK AE E EN K I K AAE E AKKAEED K KKA EEA KKA -- EE D EK KAAE ALKKEAEEAKKA 1704
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 198 TRI KK ECER E IRRL E QQLDEKDARRFQLKI A ELS A IIR K LEDRN A LLS E - E RNELLKRVR E A E SQYKPLLDKNKRLSRKN 276
Cdd:PTZ00121 1705 EEL KK KEAE E KKKA E ELKKAEEENKIKAEE A KKE A EED K KKAEE A KKD E e E KKKIAHLKK E E E KKAEEIRKEKEAVIEEE 1784
250
....*....|.
gi 1973459236 277 E D LSHAL RRME 287
Cdd:PTZ00121 1785 L D EEDEK RRME 1795
PTZ00121
PTZ00121 MAEBL; Provisional
1-309
1.37e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 42.44
E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 1 MS K RGMSSRA K G D K A EAL A ALQAANEDLR - A KLTDIQI E LQQEKSKVSKV E RE K NQ E LR --- QVREH E QH K T A VLLTELK 76
Cdd:PTZ00121 1488 AK K KAEEAKK K A D E A KKA A EAKKKADEAK k A EEAKKAD E AKKAEEAKKAD E AK K AE E KK kad ELKKA E EL K K A EEKKKAE 1567
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 77 TKLHE E KM K ELQAVRETLLRQH E AELLRVIKIKDN E NQRLQ A ll SALRDGGPE K V K TVL L SE A k EE A KK GF E VE K V K MQQ 156
Cdd:PTZ00121 1568 EAKKA E ED K NMALRKAEEAKKA E EARIEEVMKLYE E EKKMK A -- EEAKKAEEA K I K AEE L KK A - EE E KK KV E QL K K K EAE 1644
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 157 E ISELKGA K RQV EE altlviqa D KIKAAE IRSVYHLHQEEITRI KK EC E R E IRRL E QQLD E KDARR fql K IA EL saii R K 236
Cdd:PTZ00121 1645 E KKKAEEL K KAE EE -------- N KIKAAE EAKKAEEDKKKAEEA KK AE E D E KKAA E ALKK E AEEAK --- K AE EL ---- K K 1709
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1973459236 237 L E drnalls E E RNELLKRVRE AE SQY K PLLDKN K RLSRKNEDLSHALRRM E NKL K FVTQENI E MRQR A GI IR R 309
Cdd:PTZ00121 1710 K E ------- A E EKKKAEELKK AE EEN K IKAEEA K KEAEEDKKKAEEAKKD E EEK K KIAHLKK E EEKK A EE IR K 1775
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
26-264
1.99e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 41.29
E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 26 EDLR A K L TDI Q I E LQQEKSKVSKVER E KNQE L R Q VREH E Q hkt AVLLTELKTKLH E EKMKE L Q A V retl L RQH E A E LLRV 105
Cdd:COG4942 23 AEAE A E L EQL Q Q E IAELEKELAALKK E EKAL L K Q LAAL E R --- RIAALARRIRAL E QELAA L E A E ---- L AEL E K E IAEL 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 106 IKIKDNENQR L QA LL S AL - R D G GPEKVKTV L LS E AKEE A kkgfevek V KMQ Q EISE L KG A K R QVE E A L TLVIQADKIKA A 184
Cdd:COG4942 96 RAELEAQKEE L AE LL R AL y R L G RQPPLALL L SP E DFLD A -------- V RRL Q YLKY L AP A R R EQA E E L RADLAELAALR A 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 185 E IRS vyhl HQE E ITRIKK E C E R E IRR LE QQLD E K darrf Q LKI A E L SAIIRK L EDRN A L L SE E RN EL LKRVREA E SQYKP 264
Cdd:COG4942 168 E LEA ---- ERA E LEALLA E L E E E RAA LE ALKA E R ----- Q KLL A R L EKELAE L AAEL A E L QQ E AE EL EALIARL E AEAAA 238
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
424-548
2.71e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 424 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 499
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1973459236 500 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 548
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
423-747
3.07e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 41.20
E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 423 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 502
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 503 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 582
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 583 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 662
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 663 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 742
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1973459236 743 IE A QK 747
Cdd:TIGR02168 508 VK A LL 512
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
136-347
3.46e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 40.82
E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 136 L SEAK E E A KKGFEVE K V K MQQ E IS EL KGA K RQV E EA ltlv IQ A DKIKA A EIRSVYHLHQ EEI TRIK K EC E REIRR LE Q -- 213
Cdd:TIGR02169 203 L RRER E K A ERYQALL K E K REY E GY EL LKE K EAL E RQ ---- KE A IERQL A SLEEELEKLT EEI SELE K RL E EIEQL LE E ln 278
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 214 ---- Q L D E KDAR R FQL KI A EL S A I I RK LE DRN A LLSE E RNELLK R VREA E SQYKP LL DKNKR L S R KN E DLSHALRRMENK 289
Cdd:TIGR02169 279 kkik D L G E EEQL R VKE KI G EL E A E I AS LE RSI A EKER E LEDAEE R LAKL E AEIDK LL AEIEE L E R EI E EERKRRDKLTEE 358
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1973459236 290 LKFVTQ E NIEM R QRAGIIRRPSSLNDLDQSQDEREVDF LK LQ I V E QQNLI D E L SKT L E 347
Cdd:TIGR02169 359 YAELKE E LEDL R AELEEVDKEFAETRDELKDYREKLEK LK RE I N E LKREL D R L QEE L Q 416
COG2433
COG2433 Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
456-545
4.07e-03
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain]
Cd Length: 644
Bit Score: 40.61
E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 456 DA E REVKTR E -- Q L QAE V Q R AQ A RI E D LE KA L A E QGQDMKWI E EKQALY R RNQELV ---- EK I KQMET E EA RL RH E VQDA 529
Cdd:COG2433 405 ER E LTEEEE E ir R L EEQ V E R LE A EV E E LE AE L E E KDERIERL E RELSEA R SEERRE irkd RE I SRLDR E IE RL ER E LEEE 484
90
....*....|....*.
gi 1973459236 530 R DQN E L L EFRILE L E E 545
Cdd:COG2433 485 R ERI E E L KRKLER L K E 500
YhaN
COG4717 Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
416-750
4.70e-03
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain]
Cd Length: 641
Bit Score: 40.52
E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 416 D L E E GMA K E E TE L RFRQ L TM E YQ AL QRAY A L L Q E QVG gtl DA E REVKTREQ L QA E VQRAQ A RIED L EKA L A E QGQDMKWI 495
Cdd:COG4717 113 E L R E ELE K L E KL L QLLP L YQ E LE AL EAEL A E L P E RLE --- EL E ERLEELRE L EE E LEELE A ELAE L QEE L E E LLEQLSLA 189
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 496 E E KQA -- L YRRNQ EL VEKIKQM E T E EARLRH E VQDARDQN E L LE FRILELEER ER KS ------ PAISFHHTPFVD G K S P L 567
Cdd:COG4717 190 T E EEL qd L AEELE EL QQRLAEL E E E LEEAQE E LEELEEEL E Q LE NELEAAALE ER LK earlll LIAAALLALLGL G G S L L 269
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 568 QVYCEAE GV TDI V VAE L MKKLDI L GDNANLTNE E QVVVIQARTVLT L A E KW L QQI eeteaa L QRKMVDLESEK E LFSKQK 647
Cdd:COG4717 270 SLILTIA GV LFL V LGL L ALLFLL L AREKASLGK E AEELQALPALEE L E E EE L EEL ------ L AALGLPPDLSP E ELLELL 343
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 648 GYLD E ELDYRKQ A LDQANKHI LE LEAMLYD AL QQ EAG AKVA E L L SE ----- EE REK LK VAV E QWKR Q VMSE L R E R ---- D 718
Cdd:COG4717 344 DRIE E LQELLRE A EELEEELQ LE ELEQEIA AL LA EAG VEDE E E L RA aleqa EE YQE LK EEL E ELEE Q LEEL L G E L eell E 423
330 340 350
....*....|....*....|....*....|..
gi 1973459236 719 A QILR E RM E L L QLAQQRIK ELEE RI E AQKRQI 750
Cdd:COG4717 424 A LDEE E LE E E L EELEEELE ELEE EL E ELREEL 455
COG2433
COG2433 Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
136-302
7.40e-03
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain]
Cd Length: 644
Bit Score: 39.84
E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 136 LSEAKEEAKKGFEVEK VK mqqe ISELK G A kr QV EEAL TLV I QADK ika A E IRSVYHLHQ E EIT R IKK E C E R EIRRLE Q Q L 215
Cdd:COG2433 352 FERVEKKVPPDVDRDE VK ---- ARVIR G L -- SI EEAL EEL I EKEL --- P E EEPEAEREK E HEE R ELT E E E E EIRRLE E Q V 422
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 216 D -- E KDARRFQLKIA E LSAI I RK LE DRNALLSE E RNELLKRV RE A esqykplldkn K RL S R KN E D L SHA L RRMENKLKFV 293
Cdd:COG2433 423 E rl E AEVEELEAELE E KDER I ER LE RELSEARS E ERREIRKD RE I ----------- S RL D R EI E R L ERE L EEERERIEEL 491
....*....
gi 1973459236 294 TQENIEMRQ 302
Cdd:COG2433 492 KRKLERLKE 500
PTZ00121
PTZ00121 MAEBL; Provisional
50-549
8.56e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 39.74
E-value: 8.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 50 E RE K NQEL R QVREHEQHKTAVLLT E LKTKLHEE K MKELQAVR E T ll RQHEA E LLRVIKIKD NE NQ R lqalls ALRDGGPE 129
Cdd:PTZ00121 1192 E LR K AEDA R KAEAARKAEEERKAE E ARKAEDAK K AEAVKKAE E A -- KKDAE E AKKAEEERN NE EI R ------ KFEEARMA 1263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 130 KVKTVLLSEAK EEA K K GF E VE K VKMQQEIS E L K G A -- K RQVE EA LTLV iq ADKI KA A E IRSVYHLHQEEITRI KK EC E RE 207
Cdd:PTZ00121 1264 HFARRQAAIKA EEA R K AD E LK K AEEKKKAD E A K K A ee K KKAD EA KKKA -- EEAK KA D E AKKKAEEAKKKADAA KK KA E EA 1341
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 208 IRRL E QQLD E KD A RRFQLKI AE LS A IIRKLEDRN A lls EERNELL K RVR E AESQYKPLLD K NKRLSR K NED L shalrrme 287
Cdd:PTZ00121 1342 KKAA E AAKA E AE A AADEAEA AE EK A EAAEKKKEE A --- KKKADAA K KKA E EKKKADEAKK K AEEDKK K ADE L -------- 1410
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 288 N K LKFVTQENI E MRQR A GIIRRPSSLN dl DQSQDEREV D FL K LQ i V E QQNLID E LS K TL E T A GYVKSVLERDKLLRFRKQ 367
Cdd:PTZ00121 1411 K K AAAAKKKAD E AKKK A EEKKKADEAK -- KKAEEAKKA D EA K KK - A E EAKKAE E AK K KA E E A KKADEAKKKAEEAKKADE 1487
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 368 R KK M A KLP K PVVV E T ff GYDE EA SLES D GSSVSYQTDRT D QTPCTPDDDLEEGMA K E E T ----- EL RFRQLTMEYQALQR 442
Cdd:PTZ00121 1488 A KK K A EEA K KKAD E A -- KKAA EA KKKA D EAKKAEEAKKA D EAKKAEEAKKADEAK K A E E kkkad EL KKAEELKKAEEKKK 1565
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 443 A YALLQEQVGGTLDAEREVKTREQLQ A EVQRAQARI E DLE K AL AE QGQDMKWIEE K QALYRRNQ E L --- VE KI K QM E T EE 519
Cdd:PTZ00121 1566 A EEAKKAEEDKNMALRKAEEAKKAEE A RIEEVMKLY E EEK K MK AE EAKKAEEAKI K AEELKKAE E E kkk VE QL K KK E A EE 1645
490 500 510
....*....|....*....|....*....|
gi 1973459236 520 ARLRH E VQD A RDQ N ELLEFRILELE E RER K 549
Cdd:PTZ00121 1646 KKKAE E LKK A EEE N KIKAAEEAKKA E EDK K 1675
PRK05771
PRK05771 V-type ATP synthase subunit I; Validated
31-298
8.74e-03
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain]
Cd Length: 646
Bit Score: 39.53
E-value: 8.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 31 KL TDIQIE L QQEKSKVS KV EREKNQ EL RQVR E H E qhk TAVLLT E L K TK lh EE KMK EL qavr E TLLRQH E A E LL R VIKIKD 110
Cdd:PRK05771 61 KL RSYLPK L NPLREEKK KV SVKSLE EL IKDV E E E --- LEKIEK E I K EL -- EE EIS EL ---- E NEIKEL E Q E IE R LEPWGN 131
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 111 nenqr LQAL LS A L RDGGPEK V KTVLLS E A K E E AK K gf EVEK V KMQQE IS EL KG AK rqveeal TL V IQAD K IKAA E I rsvy 190
Cdd:PRK05771 132 ----- FDLD LS L L LGFKYVS V FVGTVP E D K L E EL K -- LESD V ENVEY IS TD KG YV ------- YV V VVVL K ELSD E V ---- 193
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1973459236 191 hlhqeeitrikkec E R E IRR L E qqldekd AR R FQ L K - IAEL S AI IR KLEDRNALLSE ER NE LL KRVR E AESQ Y kplldk N 269
Cdd:PRK05771 194 -------------- E E E LKK L G ------- FE R LE L E e EGTP S EL IR EIKEELEEIEK ER ES LL EELK E LAKK Y ------ L 246
250 260
....*....|....*....|....*....
gi 1973459236 270 KR L SRKN E D L SHA L R R M E NKL KF VTQENI 298
Cdd:PRK05771 247 EE L LALY E Y L EIE L E R A E ALS KF LKTDKT 275
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
