|
Name |
Accession |
Description |
Interval |
E-value |
| SMYLE_N |
pfam18615 |
Short myomegalin-like EB1 binding proteins, N-terminal domain; This N-terminal region is found ... |
1-376 |
0e+00 |
|
Short myomegalin-like EB1 binding proteins, N-terminal domain; This N-terminal region is found in SMYLE (for short myomegalin-like EB1 binding protein). It includes the SMYLE homology (SmyH) domain found in the first 100 residues at the N terminus. This conserved SmyH domain is required and sufficient for PKA scaffolding protein AKAP9, and the pericentrosomal protein CDK5RAP2 binding.
Pssm-ID: 465822 Cd Length: 387 Bit Score: 680.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1 MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVPRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQ 80
Cdd:pfam18615 1 MKEACRICARELCGNQRRWIFHPAAKLNLQVLLSHALGRELTRDGRGEFACSKCAFMLDRMYRFDTVIARVEALSIERLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 81 KLLLEKDRLKFCIASMYRKNN-DDSGAEIKAGNGTVDMSVLPDARYSALLQEDFAYSGFECWVENEDQIQEPHSCHGSEG 159
Cdd:pfam18615 81 KLLLEKDRLRQCIAGLYRKNNsEESGPEDKVGDGTVDLSGLPDARYSALLQEDLAYSGYESWAEHEEQALDHHHCHASEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 160 PGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISCGPSSRWSTSICTEEPALSEVGPPDLASTKVPPDGESMEEETPG 239
Cdd:pfam18615 161 PGSRPRRCRGCAALRVADSDYEAVCKVPRKVARSISCGPSTRYSASTGNEEPSVSELGPATLGNTKSPCEGESMEEGSPA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 240 SSVESLDASVQ-ASPPQQKDEETERSAKELGKCDCCSDD--QAPQHGCNHKLELALSMIKGLDYKPIQSPRGSRLPIPVK 316
Cdd:pfam18615 241 SSVESLDTTVDvVQPPQQKDEESDKGEKDDRKCDQSSEEktTASSSLSSSGLELALSLLRGCEYRPVQSPRGSRLPVLVK 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392235 317 SSLPGAKPGPSMTDGV-------SSGFLNRSLKPLYKTPVSYPLELSDLQELWDDLCEDYLPLRVQP 376
Cdd:pfam18615 321 SSLSPGGLSYPLLDGSpgaglvcSTSFLSALREPFPQTPLDLQLELSELEELWLDLYVEYPPLRLQQ 387
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
403-1201 |
1.69e-18 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 93.20 E-value: 1.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 403 HLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLH 482
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 483 QSQlgqlhssegTSPAQQQVALLDLQSALFCSQLEIQKLqrvvrqkERQLADAKQCVQFVEAAAHESEQQKEASWKHNQE 562
Cdd:TIGR02168 313 NLE---------RQLEELEAQLEELESKLDELAEELAEL-------EEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 563 LRKALQQLQEELQNKSQQLRAWEaekyNEIRTQEQNIQHLNHSLshkEQLLQEFRELLQYRDNSDktLEANEMLLEKLRQ 642
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLN----NEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAE--LKELQAELEELEE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 643 RIHDKAVALERAIdekfSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQ 722
Cdd:TIGR02168 448 ELEELQEELERLE----EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 723 WLKEEMETKfSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEElcqrlqrkermlqDLLSDRNKQVL 802
Cdd:TIGR02168 524 VLSELISVD-EGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPL-------------DSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 803 EHEM--EIQGLLQSVSTREqESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAE-VTPTGRLGKQTDQG 879
Cdd:TIGR02168 590 DREIlkNIEGFLGVAKDLV-KFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDlVRPGGVITGGSAKT 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 880 SMQIPSRDdSTSLTAKEDVSIPRSTLGDLDT-VAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA 958
Cdd:TIGR02168 669 NSSILERR-REIEELEEKIEELEEKIAELEKaLAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 959 DMESLTRNIQIKEDLIKDLQMQLvdpedipamERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDERSRLNE 1038
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEELEERL---------EEAEEELAEAEAEIEELEAQIEQLK-EELKALREALDELRAELTLLNE 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1039 ALQAERQLYSSLVKFHAHPESSERDRT------------LQVELEGAQVLRSRLEEVLGRSLERLNRLET---LAAIGGA 1103
Cdd:TIGR02168 818 EAANLRERLESLERRIAATERRLEDLEeqieelsediesLAAEIEELEELIEELESELEALLNERASLEEalaLLRSELE 897
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1104 AAGDDTEDTSTEFTDSieEEAAHHSHQQLVKVALEKSLATVETQNpsfsppspmggdsnrcLQE---EMLHLRAEFHQHL 1180
Cdd:TIGR02168 898 ELSEELRELESKRSEL--RRELEELREKLAQLELRLEGLEVRIDN----------------LQErlsEEYSLTLEEAEAL 959
|
810 820
....*....|....*....|....*.
gi 2056392235 1181 EEKR-----KAEEELKELKAQIEEAG 1201
Cdd:TIGR02168 960 ENKIeddeeEARRRLKRLENKIKELG 985
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
518-1274 |
4.44e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 88.58 E-value: 4.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 518 IQKLQRVVRQKERQL----ADAKQCVQFVEAAAHESE----------QQKEASWKHNQELRKALQQLQEELQNKSQ---- 579
Cdd:TIGR02168 188 LDRLEDILNELERQLksleRQAEKAERYKELKAELRElelallvlrlEELREELEELQEELKEAEEELEELTAELQelee 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 580 ---QLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAID 656
Cdd:TIGR02168 268 kleELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 657 E---KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAK----GLEVEQLSTTCQNLQWLKEEME 729
Cdd:TIGR02168 348 ElkeELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEierlEARLERLEDRRERLQQEIEELL 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 730 TKFSRWQ-KEQESIIQQLQTSLHDRNKEVEDLSATLlcKLGPGQSEIAEEL-------CQRLQRKERMLQDLL------S 795
Cdd:TIGR02168 428 KKLEEAElKELQAELEELEEELEELQEELERLEEAL--EELREELEEAEQAldaaereLAQLQARLDSLERLQenlegfS 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 796 DRNKQVLEHEMEIQGLLQSVSTR-------EQESQAAAEKLVQALMERNSE-----LQALRQYLGGRDSLMsqAPISNQQ 863
Cdd:TIGR02168 506 EGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALGGRLQAVVVENLNaakkaIAFLKQNELGRVTFL--PLDSIKG 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 864 AEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSiprSTLGDLDTVAGLEKELSNAKEELE----------------L 927
Cdd:TIGR02168 584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS---YLLGGVLVVDDLDNALELAKKLRPgyrivtldgdlvrpggV 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 928 MAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPamERLTQEVLLLREKVASV 1007
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL--EELSRQISALRKDLARL 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1008 ESQGQEISgNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKfhahpESSERDRTLQVELEGAQVLRSRLEEVLGRs 1087
Cdd:TIGR02168 739 EAEVEQLE-ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA-----EIEELEAQIEQLKEELKALREALDELRAE- 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1088 LERLNRLETLAAIGGAAAGDDTEDTSTEFTDsIEEEAAHHSHQQLvkvALEKSLATVETQNPSFSPPSPMGGDSNRCLQE 1167
Cdd:TIGR02168 812 LTLLNEEAANLRERLESLERRIAATERRLED-LEEQIEELSEDIE---SLAAEIEELEELIEELESELEALLNERASLEE 887
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1168 EMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGfSSVSHIRNTMLSLCLENAELKEQmgeaMSDGWEIEEDkekgevMV 1247
Cdd:TIGR02168 888 ALALLRSELEELSEELRELESKRSELRRELEELR-EKLAQLELRLEGLEVRIDNLQER----LSEEYSLTLE------EA 956
|
810 820
....*....|....*....|....*..
gi 2056392235 1248 ETVVTKEGLSESSLQAEFRKLQGKLKN 1274
Cdd:TIGR02168 957 EALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
451-1020 |
5.62e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 5.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 451 ETLKsRERETEELYQVIEgqndtmAKLREMLHQSQLGQLHSsegtspAQQQVALLDLQSALfcSQLEIQKLQRVVRQKER 530
Cdd:COG1196 203 EPLE-RQAEKAERYRELK------EELKELEAELLLLKLRE------LEAELEELEAELEE--LEAELEELEAELAELEA 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 531 QLADAKQcvqfveaAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKE 610
Cdd:COG1196 268 ELEELRL-------ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 611 QLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSAL---EEKEKELRQLRLAVRERDHDLERLR 687
Cdd:COG1196 341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALraaAELAAQLEELEEAEEALLERLERLE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 688 DVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCK 767
Cdd:COG1196 421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 768 ---LGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTR-EQESQAAAEKLVQALMER------- 836
Cdd:COG1196 501 adyEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEdDEVAAAAIEYLKAAKAGRatflpld 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 837 ----------NSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLG 906
Cdd:COG1196 581 kiraraalaaALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 907 DLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA-DMESLTRNIQIKEDLIKDLQMQLVDPE 985
Cdd:COG1196 661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAeEERLEEELEEEALEEQLEAEREELLEE 740
|
570 580 590
....*....|....*....|....*....|....*
gi 2056392235 986 DIPAMERLTQEVLLLREKVASVESQGQEISGNRRQ 1020
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLERE 775
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
519-1201 |
9.82e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.28 E-value: 9.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 519 QKLQRV---VRQKERQLA----DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEkyne 591
Cdd:COG1196 186 ENLERLediLGELERQLEplerQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAE---- 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 592 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQ 671
Cdd:COG1196 262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 672 LRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTtcQNLQWLKEEMETkfsrwQKEQESIIQQLQTSLH 751
Cdd:COG1196 342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--ELLEALRAAAEL-----AAQLEELEEAEEALLE 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 752 DRNKEVEDLSATLLcklgpgQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQ 831
Cdd:COG1196 415 RLERLEEELEELEE------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 832 ALMERNSELQALRQYLGGRDSLMSQAPISnQQAEVTPTGRLGKQTDQGsmqiPSRDDSTSLTAKEDVSIPRSTLGDLDTV 911
Cdd:COG1196 489 AAARLLLLLEAEADYEGFLEGVKAALLLA-GLRGLAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAI 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 912 AGLEKELSNAKEELELMAKKERESQMELSALQSMMA--VQEEELQVQAADMESLTRNIQIKEDLIKDlqmqlvDPEDIPA 989
Cdd:COG1196 564 EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAavDLVASDLREADARYYVLGDTLLGRTLVAA------RLEAALR 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 990 MERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSslvkfhahpESSERDRTLQVE 1069
Cdd:COG1196 638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE---------EALLAEEEEERE 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1070 LEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAhhshqqlvkvalekslatvetqnp 1149
Cdd:COG1196 709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE------------------------ 764
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 1150 sfsppspmggdsnrclqeemlhlraefhqhleekrkAEEELKELKAQIEEAG 1201
Cdd:COG1196 765 ------------------------------------LERELERLEREIEALG 780
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
554-1294 |
1.56e-12 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 73.47 E-value: 1.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 554 EASW-KHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQ---------------------HLNHSLSHKEQ 611
Cdd:pfam02463 161 EAAGsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKaleyyqlkekleleeeyllylDYLKLNEERID 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 612 LLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLS 691
Cdd:pfam02463 241 LLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 692 SNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHD----RNKEVEDLSATLLCK 767
Cdd:pfam02463 321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeserLSSAAKLKEEELELK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 768 LGPGQSEiaeelcQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQ---ALR 844
Cdd:pfam02463 401 SEEEKEA------QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKkseDLL 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 845 QYLGGRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEdvsiPRSTLGDLDTVAGLEKELSNAKEE 924
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS----AHGRLGDLGVAVENYKVAISTAVI 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 925 LELMAKK------ERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQmQLVDPEDIPAMERLTQEVL 998
Cdd:pfam02463 551 VEVSATAdeveerQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK-ATLEADEDDKRAKVVEGIL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 999 LLREKVASVESQGQEISGNRRQQlllMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRS 1078
Cdd:pfam02463 630 KDTELTKLKESAKAKESGLRKGV---SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1079 RLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNpsfsppSPMG 1158
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL------AEER 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1159 GDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIRNTMLSlcLENAELKEQMGEAMSDGWEIEE 1238
Cdd:pfam02463 781 EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELE--ELALELKEEQKLEKLAEEELER 858
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 2056392235 1239 DKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIinlLKEQLVLSSKEGN 1294
Cdd:pfam02463 859 LEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEE---KKELEEESQKLNL 911
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
562-832 |
3.44e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.41 E-value: 3.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 562 ELRKALQQLQEE---------LQNKSQQLRAWEaeKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDnsdKTLEA 632
Cdd:TIGR02169 195 EKRQQLERLRRErekaeryqaLLKEKREYEGYE--LLKEKEALERQKEAIERQLASLEEELEKLTEEISELE---KRLEE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 633 NEMLLEKLRQRIHDKAVALERAIDEKfsaLEEKEKELRQLRLAVRERDHDLERLrdvlssnEATMQSMESLLRAKGLEVE 712
Cdd:TIGR02169 270 IEQLLEELNKKIKDLGEEEQLRVKEK---IGELEAEIASLERSIAEKERELEDA-------EERLAKLEAEIDKLLAEIE 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 713 QLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQtSLHDRNKEVEDLSATLLCKLGPGQSEIAEelcqrLQRKERMLQD 792
Cdd:TIGR02169 340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELE-EVDKEFAETRDELKDYREKLEKLKREINE-----LKRELDRLQE 413
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2056392235 793 LLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQA 832
Cdd:TIGR02169 414 ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
372-1095 |
3.10e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.32 E-value: 3.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 372 LRVQPMTEELLKQQK-LNSH-------ETTITQQSVSDSHL----AELQEKIQQTEATNKILQEKLNEMSYELKCAQESS 439
Cdd:TIGR02168 274 LEVSELEEEIEELQKeLYALaneisrlEQQKQILRERLANLerqlEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 440 QKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREML--HQSQLGQLhSSEGTSPAQQQVALLDLQSALFCSQLE 517
Cdd:TIGR02168 354 ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIasLNNEIERL-EARLERLEDRRERLQQEIEELLKKLEE 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 518 --IQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELR----------KALQQLQEELQNKSQQLRAWE 585
Cdd:TIGR02168 433 aeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAErelaqlqarlDSLERLQENLEGFSEGVKALL 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 586 AEKyneiRTQEQNIQHLNHSLSHKEQLLQE----FRELLQY--RDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKF 659
Cdd:TIGR02168 513 KNQ----SGLSGILGVLSELISVDEGYEAAieaaLGGRLQAvvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 660 SALEEKEKELRQLRLAVRERDHDlERLRDVLSS---------NEATMQSMESLLRAKGLEVeqlstTCQNLQWLKEEMET 730
Cdd:TIGR02168 589 NDREILKNIEGFLGVAKDLVKFD-PKLRKALSYllggvlvvdDLDNALELAKKLRPGYRIV-----TLDGDLVRPGGVIT 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 731 KFSRwqkEQESIIQQlqtslhdRNKEVEDLSATLlcKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQG 810
Cdd:TIGR02168 663 GGSA---KTNSSILE-------RRREIEELEEKI--EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 811 LLQSVSTREQESQAAAEKLVQAlmerNSELQALRQYLGGRDSLMSQAPISNQQAEVTptgrlgKQTDQGSMQipsrddst 890
Cdd:TIGR02168 731 LRKDLARLEAEVEQLEERIAQL----SKELTELEAEIEELEERLEEAEEELAEAEAE------IEELEAQIE-------- 792
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 891 slTAKEDVSIPRSTLgdldtvAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIK 970
Cdd:TIGR02168 793 --QLKEELKALREAL------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 971 EDLIKDLQMQLVDPEDIpaMERLTQEVLLLREKVASVESQGQEISGNR---RQQLLLMLEGLVDERSRLNEALQAERQLY 1047
Cdd:TIGR02168 865 EELIEELESELEALLNE--RASLEEALALLRSELEELSEELRELESKRselRRELEELREKLAQLELRLEGLEVRIDNLQ 942
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 2056392235 1048 SSLvkfhahpesSERdrtLQVELEGAQVLRSRLEEVLGRSLERLNRLE 1095
Cdd:TIGR02168 943 ERL---------SEE---YSLTLEEAEALENKIEDDEEEARRRLKRLE 978
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
382-1006 |
3.17e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.20 E-value: 3.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 382 LKQQKLNSHETTI----TQQSVSDSHLAELQEKIQQTEATNKILQEKLNEmsyelkcAQESSQKQDGTIQNLKETLKSRE 457
Cdd:COG1196 243 ELEAELEELEAELeeleAELAELEAELEELRLELEELELELEEAQAEEYE-------LLAELARLEQDIARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 458 RETEELyqviegqndtmaklremlhqsqlgqlhssegtspaqqqvalldlqsalfcsQLEIQKLQRVVRQKERQLADAkq 537
Cdd:COG1196 316 ERLEEL---------------------------------------------------EEELAELEEELEELEEELEEL-- 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 538 cvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFR 617
Cdd:COG1196 343 -----EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 618 ELLQYRDNSDKTLEANEMLLEKLRQRihdkavalERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATM 697
Cdd:COG1196 418 RLEEELEELEEALAELEEEEEEEEEA--------LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 698 QSMESLLRAkgleveqlsttcqnlqwLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVED-LSATLLCKLGPGQSEIA 776
Cdd:COG1196 490 AARLLLLLE-----------------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAaYEAALEAALAAALQNIV 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 777 EELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEkLVQALMERNSELQALRQYLGGRDSLmSQ 856
Cdd:COG1196 553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL-VASDLREADARYYVLGDTLLGRTLV-AA 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 857 APISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQ 936
Cdd:COG1196 631 RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 937 MELSALQSmmAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVAS 1006
Cdd:COG1196 711 EAEEERLE--EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
369-687 |
3.91e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.86 E-value: 3.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 369 YLPLRVQPMTEELLKQQKLnsHETTITQQSVSDSHLAELQEKIQQteatnkiLQEKLNEMSYELKCAQESSQKQDGTIQN 448
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRE--LSSLQSELRRIENRLDELSQELSD-------ASRKIGEIEKEIEQLEQEEEKLKERLEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 449 LKETLKSRERETEELYQVIEGQNDTMAKLREMLH--QSQLGQLHSSEGTSPAQQQVALL---------------DLQSAL 511
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHklEEALNDLEARLSHSRIPEIQAELskleeevsriearlrEIEQKL 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 512 FCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAekynE 591
Cdd:TIGR02169 822 NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA----Q 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 592 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLE----------ANEMLLEKLRQRIHDKAVALE-------RA 654
Cdd:TIGR02169 898 LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedeeipEEELSLEDVQAELQRVEEEIRalepvnmLA 977
|
330 340 350
....*....|....*....|....*....|....*....
gi 2056392235 655 IDE------KFSALEEKEKELRQLRLAVRERDHDLERLR 687
Cdd:TIGR02169 978 IQEyeevlkRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
383-765 |
4.93e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.04 E-value: 4.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 383 KQQKLNSHETTITQQSVSDSH-LAELQEKIQQTEATNKILQEKLNEMS-YELKCAQESSQKQDGTIQNLKETLKSRERET 460
Cdd:TIGR04523 244 KTTEISNTQTQLNQLKDEQNKiKKQLSEKQKELEQNNKKIKELEKQLNqLKSEISDLNNQKEQDWNKELKSELKNQEKKL 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 461 EELYQVIEGQNDTMAKLREmlhqsQLGQLHSSegtspaqqqvaLLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQ 540
Cdd:TIGR04523 324 EEIQNQISQNNKIISQLNE-----QISQLKKE-----------LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIK 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 541 FVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQ---LRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFR 617
Cdd:TIGR04523 388 NLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEierLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLE 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 618 ELLQYRDNSDKTLEANemlLEKLRQRIHDKAVALERAIDEKfSALEEKEKELRQLRLAVRERDHDLE----RLRDVLSSN 693
Cdd:TIGR04523 468 TQLKVLSRSINKIKQN---LEQKQKELKSKEKELKKLNEEK-KELEEKVKDLTKKISSLKEKIEKLEsekkEKESKISDL 543
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 694 EATMQSMESLLRAKGLEvEQLSTTCQNLQWLKEEmETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLL 765
Cdd:TIGR04523 544 EDELNKDDFELKKENLE-KEIDEKNKEIEELKQT-QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
419-1199 |
6.49e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 6.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 419 KILQEKLNEMS-YELKCAQESSQKQdgtIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEgt 495
Cdd:TIGR02169 214 QALLKEKREYEgYELLKEKEALERQ---KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEElnKKIKDLGEEE-- 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 496 sPAQQQVALLDLQSalfcsqlEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQ 575
Cdd:TIGR02169 289 -QLRVKEKIGELEA-------EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 576 NKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQ---RIHDKAVALE 652
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAaiaGIEAKINELE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 653 RAIDEKFSALEEKEKELRQLRlavrerdHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLqwlkEEMETKF 732
Cdd:TIGR02169 441 EEKEDKALEIKKQEWKLEQLA-------ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS----EERVRGG 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 733 SRWQKEQESIIQQLQTSLHDRNKeVEDLSATLLCKLGPGQ--------SEIAEELCQRLQRKE--RM----LQDLLSDRN 798
Cdd:TIGR02169 510 RAVEEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRlnnvvvedDAVAKEAIELLKRRKagRAtflpLNKMRDERR 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 799 KQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQ--ALMERnseLQALRQYLGG------------RDSLMSQAPISNQQA 864
Cdd:TIGR02169 589 DLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGdtLVVED---IEAARRLMGKyrmvtlegelfeKSGAMTGGSRAPRGG 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 865 EVTPTgRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQS 944
Cdd:TIGR02169 666 ILFSR-SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEE 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 945 MMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMER---LTQEVLLLREKVASVESQGQEISG--NRR 1019
Cdd:TIGR02169 745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeIQAELSKLEEEVSRIEARLREIEQklNRL 824
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1020 QQLLLMLEGLVDERSRLNEALQAERqlysslVKFHAHPESSE-RDRTLQVELEGAQV----LRSRLEEVLGRSLERLNRL 1094
Cdd:TIGR02169 825 TLEKEYLEKEIQELQEQRIDLKEQI------KSIEKEIENLNgKKEELEEELEELEAalrdLESRLGDLKKERDELEAQL 898
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1095 ETLaaiggaaagddtEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSnRCLQEEMLHLRA 1174
Cdd:TIGR02169 899 REL------------ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEE 965
|
810 820 830
....*....|....*....|....*....|....*
gi 2056392235 1175 EFH----------QHLEEKRKAEEELKELKAQIEE 1199
Cdd:TIGR02169 966 EIRalepvnmlaiQEYEEVLKRLDELKEKRAKLEE 1000
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
453-954 |
2.13e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.86 E-value: 2.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 453 LKSRERETEELYQVIEGQND-----TMAKLREMLHQS---QLGQLHSSEGTSPAQQQVALLDLQSAL---FCSQLEIQKL 521
Cdd:COG4717 14 FRDRTIEFSPGLNVIYGPNEagkstLLAFIRAMLLERlekEADELFKPQGRKPELNLKELKELEEELkeaEEKEEEYAEL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 522 QRVVRQKERQLADAKQcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEaEKYNEIRTQEQNIQH 601
Cdd:COG4717 94 QEELEELEEELEELEA-----ELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELE-ERLEELRELEEELEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 602 LNHSLSHKEQLLQEfrellQYRDNSDKTLEANEMLLEKLrQRIHDKAVALERAIDEKFSALEEKEKELRQLRlAVRERDH 681
Cdd:COG4717 168 LEAELAELQEELEE-----LLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEELEELEEELEQLE-NELEAAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 682 DLERLRDVLSSNEATmqSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEvEDLS 761
Cdd:COG4717 241 LEERLKEARLLLLIA--AALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL-EELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 762 ATLLCKL-------GPGQSEIAEELCQRLQRKERMLQDLLSDRNK-QVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL 833
Cdd:COG4717 318 EEELEELlaalglpPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAEAGVEDEEELRAALEQAEEY 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 834 MERNSELQALRQYLGgrdslmSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTS--LTAKEDVSIPRSTLGDLDTV 911
Cdd:COG4717 398 QELKEELEELEEQLE------ELLGELEELLEALDEEELEEELEELEEELEELEEELEelREELAELEAELEQLEEDGEL 471
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 2056392235 912 AGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQ 954
Cdd:COG4717 472 AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
369-1001 |
2.65e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 62.83 E-value: 2.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 369 YLPLRVQPMTEEL--LKQQKLNSHETTITQQsvsdshlaelQEKIQQTEATNKILQEKLNEMSyelkcaqESSQKQDGTI 446
Cdd:pfam15921 235 YLKGRIFPVEDQLeaLKSESQNKIELLLQQH----------QDRIEQLISEHEVEITGLTEKA-------SSARSQANSI 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 447 QNLKETLKSRERETEELYqviegqndtMAKLREMlhQSQLGQLHSS--EGTSPAQQQVALLDLQSALFCSQLEIQKLQRv 524
Cdd:pfam15921 298 QSQLEIIQEQARNQNSMY---------MRQLSDL--ESTVSQLRSElrEAKRMYEDKIEELEKQLVLANSELTEARTER- 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 525 vRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQEL--------------RKALQQLQEELQNKSQQLRAWEAEKYN 590
Cdd:pfam15921 366 -DQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrdtgnsitidhlRRELDDRNMEVQRLEALLKAMKSECQG 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 591 EIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALEraidEKFSALEEKEKELR 670
Cdd:pfam15921 445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQ----EKERAIEATNAEIT 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 671 QLRLAVRERDHDLERLR---DVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQesiiQQLQ 747
Cdd:pfam15921 521 KLRSRVDLKLQELQHLKnegDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK----AQLE 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 748 TSLHDRNKEVEDLSatLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAE 827
Cdd:pfam15921 597 KEINDRRLELQEFK--ILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSE 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 828 K---LVQALMERNSELQALRQYLggrdslmsQAPISNQQAEVTPTGRLGKQ---TDQGSMQIpsrddstSLTAKEDVSIP 901
Cdd:pfam15921 675 DyevLKRNFRNKSEEMETTTNKL--------KMQLKSAQSELEQTRNTLKSmegSDGHAMKV-------AMGMQKQITAK 739
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 902 RSTLGDLDT-VAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQ 980
Cdd:pfam15921 740 RGQIDALQSkIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
650 660
....*....|....*....|.
gi 2056392235 981 LVDPEDIpaMERLTQEVLLLR 1001
Cdd:pfam15921 820 FAECQDI--IQRQEQESVRLK 838
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
431-1200 |
3.14e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.78 E-value: 3.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 431 ELKCAQESSQKQDGTIQNLKETLK--SRERETEELYQviegqnDTMAKLREMlhqsqlgqlhssEGTSPAQQQVALLDLQ 508
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQ------ALLKEKREY------------EGYELLKEKEALERQK 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 509 SALfcsQLEIQKLQRVVRQKERQLAD-AKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAE 587
Cdd:TIGR02169 240 EAI---ERQLASLEEELEKLTEEISElEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 588 KYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEK 667
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 668 ----------ELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSttcQNLQWLKEEMETKFSRWQK 737
Cdd:TIGR02169 397 lkreinelkrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELYD 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 738 EQESiIQQLQTSLHDRNKEVEDLSATL--LCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSV 815
Cdd:TIGR02169 474 LKEE-YDRVEKELSKLQRELAEAEAQAraSEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNV 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 816 STreqESQAAAEKLVQALMERNselqalrqylGGRdslMSQAPISNQQAEVTPTGRLGKQTDQG-SMQIPSRDD------ 888
Cdd:TIGR02169 553 VV---EDDAVAKEAIELLKRRK----------AGR---ATFLPLNKMRDERRDLSILSEDGVIGfAVDLVEFDPkyepaf 616
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 889 -----STSLTakEDVSIPRSTLGDLDTVAgLEKEL----------SNAKEELELMAKKERESQMELSA-LQSMmavqEEE 952
Cdd:TIGR02169 617 kyvfgDTLVV--EDIEAARRLMGKYRMVT-LEGELfeksgamtggSRAPRGGILFSRSEPAELQRLRErLEGL----KRE 689
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 953 LQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDipAMERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDE 1032
Cdd:TIGR02169 690 LSSLQSELRRIENRLDELSQELSDASRKIGEIEK--EIEQLEQEEEKLKERLEELEEDLSSLE-QEIENVKSELKELEAR 766
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1033 RSRLNEALQAERQlysSLVKFHAHPeSSERDRTLQVELEGAQVLRSRLEEVLgRSLER-LNRLeTLAAIGGAAAGDDTED 1111
Cdd:TIGR02169 767 IEELEEDLHKLEE---ALNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARL-REIEQkLNRL-TLEKEYLEKEIQELQE 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1112 TSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQnpsfsppspmggdsNRCLQEEMLHLRAEFHQHLEEKRKAEEELK 1191
Cdd:TIGR02169 841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA--------------LRDLESRLGDLKKERDELEAQLRELERKIE 906
|
....*....
gi 2056392235 1192 ELKAQIEEA 1200
Cdd:TIGR02169 907 ELEAQIEKK 915
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
521-1012 |
1.47e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 60.14 E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 521 LQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRaweaEKYNEIRTQEQNIQ 600
Cdd:pfam05557 11 LSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALR----EQAELNRLKKKYLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 601 HLNHSLSHKEQLL-----------QEFRELLQYRDNSDKTLEANEMLLEKLRQRiHDKAVALERAIDEKFSALEEKEKEL 669
Cdd:pfam05557 87 ALNKKLNEKESQLadarevisclkNELSELRRQIQRAELELQSTNSELEELQER-LDLLKAKASEAEQLRQNLEKQQSSL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 670 RQLRLAVRERDHDLERLRD----VLSSNE--ATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEE---METKFSRWQKEQE 740
Cdd:pfam05557 166 AEAEQRIKELEFEIQSQEQdseiVKNSKSelARIPELEKELERLREHNKHLNENIENKLLLKEEvedLKRKLEREEKYRE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 741 SII------QQLQTSLHDRNKEVEDLSATLlcklgPGQSEIAEELCQrLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQS 814
Cdd:pfam05557 246 EAAtlelekEKLEQELQSWVKLAQDTGLNL-----RSPEDLSRRIEQ-LQQREIVLKEENSSLTSSARQLEKARRELEQE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 815 VS----------TREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQ---------------------- 862
Cdd:pfam05557 320 LAqylkkiedlnKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQllerieeaedmtqkmqahneem 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 863 -----QAEVTPTG-RLGKQTDQGSMQIPSRDDST--SLTAKEDVSIPRStlgDLDTVAGLEKELSNAKEELEL-MAKKER 933
Cdd:pfam05557 400 eaqlsVAEEELGGyKQQAQTLERELQALRQQESLadPSYSKEEVDSLRR---KLETLELERQRLREQKNELEMeLERRCL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 934 ESQMELS---ALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIP--AMERLTQEVLLLREKVASVE 1008
Cdd:pfam05557 477 QGDYDPKktkVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPetTSTMNFKEVLDLRKELESAE 556
|
....
gi 2056392235 1009 SQGQ 1012
Cdd:pfam05557 557 LKNQ 560
|
|
| Olduvai |
pfam06758 |
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ... |
1714-1783 |
2.30e-08 |
|
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.
Pssm-ID: 429104 [Multi-domain] Cd Length: 68 Bit Score: 52.81 E-value: 2.30e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1714 DHKSEKDQaglEPLALRLSRELQEKEKViEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACS 1783
Cdd:pfam06758 1 DEEEEEDQ---EPLAPRLSRELPEVEEQ-EVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSS 66
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
420-857 |
3.87e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 3.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 420 ILQEKLNEMSYEL-KCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMlhQSQLGQLhssegtspa 498
Cdd:COG4717 46 MLLERLEKEADELfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL--EAELEEL--------- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 499 QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKeaswkhnQELRKALQQLQEELQNKS 578
Cdd:COG4717 115 REELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE-------AELAELQEELEELLEQLS 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 579 QQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEK 658
Cdd:COG4717 188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 659 FSALEEKEKELRQLRLAVRErdHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLqWLKEEMETKFSRWQKE 738
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLA--LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL-GLPPDLSPEELLELLD 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 739 QESIIQQLQTSLHDRNKEV-----EDLSATLLCKLGPGQSEIAEELCQRLQRKERmLQDLLSDRNKQVLEHEMEIQGLLQ 813
Cdd:COG4717 345 RIEELQELLREAEELEEELqleelEQEIAALLAEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLE 423
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2056392235 814 SVSTREQESQaaAEKLVQALMERNSELQALRQYLGGRDSLMSQA 857
Cdd:COG4717 424 ALDEEELEEE--LEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
386-856 |
6.71e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 58.13 E-value: 6.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 386 KLNSHETTITQqsvSDSHLAELQEKIQQTEATNKILQEKLNEmsYELKcaQESSQKQDGTIQNLKETLKSRERETEELYQ 465
Cdd:PRK02224 207 RLNGLESELAE---LDEEIERYEEQREQARETRDEADEVLEE--HEER--REELETLEAEIEDLRETIAETEREREELAE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 466 VIEGQNDTMAKLREMLHqsqlGQLHSSEGTSPAQQqvALLDLQSALfcsQLEIQKLQRVVRQKERQLADA-KQCVQFVEA 544
Cdd:PRK02224 280 EVRDLRERLEELEEERD----DLLAEAGLDDADAE--AVEARREEL---EDRDEELRDRLEECRVAAQAHnEEAESLRED 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 545 AAHESEQQKEASWKhNQELRKALQQLQEELQNKSQQLRAWEAE------KYNEIRTQEQNIQHLNHSL-SHKEQLLQEFR 617
Cdd:PRK02224 351 ADDLEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEieelreRFGDAPVDLGNAEDFLEELrEERDELREREA 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 618 ELLQYRDNSDKTLEANEMLLEKLR-----QRIHDKAVAleRAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDV--- 689
Cdd:PRK02224 430 ELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLvea 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 690 ---LSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQK---EQESIIQQLQTSLHDRNKEVEDLSAT 763
Cdd:PRK02224 508 edrIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREaaaEAEEEAEEAREEVAELNSKLAELKER 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 764 L--LCKLGPGQSEIAE--ELCQRLQRKERMLQDL-------LSDRNKQVLEHEMEIQGllqsvsTREQESQAAAEKLVQA 832
Cdd:PRK02224 588 IesLERIRTLLAAIADaeDEIERLREKREALAELnderrerLAEKRERKRELEAEFDE------ARIEEAREDKERAEEY 661
|
490 500
....*....|....*....|....
gi 2056392235 833 LMERNSELQALRQylgGRDSLMSQ 856
Cdd:PRK02224 662 LEQVEEKLDELRE---ERDDLQAE 682
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
403-705 |
7.42e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 58.06 E-value: 7.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 403 HLAELQEKIQQTEATNKILQEKLNEMSYEL-KCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDtmakLREML 481
Cdd:TIGR00618 557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIpNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDL----QDVRL 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 482 HQSQLGQLHSSEGTSPAQQQVALL---DLQSALFCSQLEIQKLQRVVRQ------KERQLADAKQCVQFVEAAAHESEQQ 552
Cdd:TIGR00618 633 HLQQCSQELALKLTALHALQLTLTqerVREHALSIRVLPKELLASRQLAlqkmqsEKEQLTYWKEMLAQCQTLLRELETH 712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 553 KEASWKHNQELRKALQQLQEELQNK----SQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDK 628
Cdd:TIGR00618 713 IEEYDREFNEIENASSSLGSDLAARedalNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNR 792
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392235 629 TLEANEMLLEKLRQRIHDKAVALEraiDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLR 705
Cdd:TIGR00618 793 LREEDTHLLKTLEAEIGQEIPSDE---DILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQ 866
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
404-618 |
1.57e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 1.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 404 LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLhQ 483
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL-A 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 484 SQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLeIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQEL 563
Cdd:COG4942 108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392235 564 RKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRE 618
Cdd:COG4942 187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
515-1199 |
2.48e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 56.52 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 515 QLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQlQEELQNKSQQLRAWEAEKYNEIRT 594
Cdd:TIGR00618 200 TLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-QLKKQQLLKQLRARIEELRAQEAV 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 595 QEQNIQHLNHSlSHKEQLLQEFRELLQYRDNSDK---TLEANEMLLEKLRQriHDKAVALERAIDEKFSALEekEKELRQ 671
Cdd:TIGR00618 279 LEETQERINRA-RKAAPLAAHIKAVTQIEQQAQRihtELQSKMRSRAKLLM--KRAAHVKQQSSIEEQRRLL--QTLHSQ 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 672 LRLAVRERDHDLERlRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQlqtsLH 751
Cdd:TIGR00618 354 EIHIRDAHEVATSI-REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL----AH 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 752 DRNKEVEDLSATLLCKLGPG---QSEIAEE-LCQRLQRKERMLQDLLSDRnKQVLEHEMEIQGLLQSVSTREQESQAAAE 827
Cdd:TIGR00618 429 AKKQQELQQRYAELCAAAITctaQCEKLEKiHLQESAQSLKEREQQLQTK-EQIHLQETRKKAVVLARLLELQEEPCPLC 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 828 KlvqALMERNSELQALRQyLGGRDSLMSQ---APISNQQAEVTPTGRLGKQTDQG---SMQIPSRDDSTSLTAKEDVSIP 901
Cdd:TIGR00618 508 G---SCIHPNPARQDIDN-PGPLTRRMQRgeqTYAQLETSEEDVYHQLTSERKQRaslKEQMQEIQQSFSILTQCDNRSK 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 902 RStlgdldtVAGLEKELSNAKEELELMAKKERESQMELSAlqsmmavQEEELQVQAADMESLTRNIQIKEDLIKDLQmql 981
Cdd:TIGR00618 584 ED-------IPNLQNITVRLQDLTEKLSEAEDMLACEQHA-------LLRKLQPEQDLQDVRLHLQQCSQELALKLT--- 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 982 vdpedipAMERLTQEVLLLREKVASVES-QGQEISGNRRQQLLLMLEGLVDE----RSRLNEALQAERQLYSSLVKFHAH 1056
Cdd:TIGR00618 647 -------ALHALQLTLTQERVREHALSIrVLPKELLASRQLALQKMQSEKEQltywKEMLAQCQTLLRELETHIEEYDRE 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1057 -PESSERDRTLQVELEGAQVLrsrLEEVLGrSLERLNRlETLAAIGGAAAGDDTEDTSTEFTDSIEEE-AAHHSHQQLVK 1134
Cdd:TIGR00618 720 fNEIENASSSLGSDLAAREDA---LNQSLK-ELMHQAR-TVLKARTEAHFNNNEEVTAALQTGAELSHlAAEIQFFNRLR 794
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2056392235 1135 VALEKSLATVETQNPSFSPPspmGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEE 1199
Cdd:TIGR00618 795 EEDTHLLKTLEAEIGQEIPS---DEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEE 856
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
419-1157 |
3.84e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.89 E-value: 3.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 419 KILQEKLNEmSYELKCAQESSQKQdgTIQNLKETLKSREREteelyqviegqNDTMAKLREMLHQSQLGQLHSSEGTSPA 498
Cdd:pfam15921 88 KDLQRRLNE-SNELHEKQKFYLRQ--SVIDLQTKLQEMQME-----------RDAMADIRRRESQSQEDLRNQLQNTVHE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 499 QQQVALLDlQSALFCSQLEIQKLQRVVRQKERQLADAKQC-VQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNK 577
Cdd:pfam15921 154 LEAAKCLK-EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIlVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 578 -----------SQQLRAWEAEKYNEI--------------------------------RTQEQNIQ-------------- 600
Cdd:pfam15921 233 isylkgrifpvEDQLEALKSESQNKIelllqqhqdrieqliseheveitgltekassaRSQANSIQsqleiiqeqarnqn 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 601 -----HLNHSLSHKEQLLQEFRELLQYRDNSDKTLE-----ANEMLLEKLRQR--IHDKAVALERAIDEKFSALEEKEKE 668
Cdd:pfam15921 313 smymrQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERdqFSQESGNLDDQLQKLLADLHKREKE 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 669 LRQlrlavrERDHDlERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQW-LKEEMETKFSRWQKEQE------S 741
Cdd:pfam15921 393 LSL------EKEQN-KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSeCQGQMERQMAAIQGKNEslekvsS 465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 742 IIQQLQTSLHDRNKEVEDLSATllcKLGPGQSE-IAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGL--LQSVSTR 818
Cdd:pfam15921 466 LTAQLESTKEMLRKVVEELTAK---KMTLESSErTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELqhLKNEGDH 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 819 EQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTpTGRLGKQTDQGSMQIpsrDDSTSLTAKEDV 898
Cdd:pfam15921 543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE-KAQLEKEINDRRLEL---QEFKILKDKKDA 618
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 899 SIP--RSTLGDLDtvagLEK-ELSNAKEElelMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIK----E 971
Cdd:pfam15921 619 KIRelEARVSDLE----LEKvKLVNAGSE---RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKseemE 691
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 972 DLIKDLQMQLVDpedipAMERLTQEvlllREKVASVESQgqeiSGNRRQQLLLMLEGLVDERSRLnEALQAERQLYSSLV 1051
Cdd:pfam15921 692 TTTNKLKMQLKS-----AQSELEQT----RNTLKSMEGS----DGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAM 757
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1052 KfHAHPES---SERDRTLQVELEGAQVLRSRLE---EVLgRSLERlnRLETlAAIGGAAAGDDTEDTSTEFTDSIEEEaa 1125
Cdd:pfam15921 758 T-NANKEKhflKEEKNKLSQELSTVATEKNKMAgelEVL-RSQER--RLKE-KVANMEVALDKASLQFAECQDIIQRQ-- 830
|
810 820 830
....*....|....*....|....*....|..
gi 2056392235 1126 hhsHQQLVKVALEKSLATVETQNPSFSPPSPM 1157
Cdd:pfam15921 831 ---EQESVRLKLQHTLDVKELQGPGYTSNSSM 859
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
375-1226 |
4.37e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.57 E-value: 4.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 375 QPMTEELLKQQKLNSHETTItqqsvsDSHLAELQEKIQQTEATN-------KILQEKLNEMSYELKCAQESSQ------- 440
Cdd:pfam01576 110 EQLDEEEAARQKLQLEKVTT------EAKIKKLEEDILLLEDQNsklskerKLLEERISEFTSNLAEEEEKAKslsklkn 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 441 KQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLH--QSQLGQLHSSEGTSPAQQQVALLDLQSalfcSQLEI 518
Cdd:pfam01576 184 KHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAelQAQIAELRAQLAKKEEELQAALARLEE----ETAQK 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 519 QKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKeaswkhnQELRKALQQLQEELQNKSQQLRAWEaekynEIRTQ-EQ 597
Cdd:pfam01576 260 NNALKKIRELEAQISELQEDLESERAARNKAEKQR-------RDLGEELEALKTELEDTLDTTAAQQ-----ELRSKrEQ 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 598 NIQHLNHSLSHK----EQLLQEFREllqyrdnsdKTLEANEMLLEKLRQRIHDKAvALERAIDEKFSALEEKEKELRQLR 673
Cdd:pfam01576 328 EVTELKKALEEEtrshEAQLQEMRQ---------KHTQALEELTEQLEQAKRNKA-NLEKAKQALESENAELQAELRTLQ 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 674 LAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQT----- 748
Cdd:pfam01576 398 QAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtqell 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 749 --------SLHDRNKEVEDLSATLLcklgpGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGL--------- 811
Cdd:pfam01576 478 qeetrqklNLSTRLRQLEDERNSLQ-----EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALeegkkrlqr 552
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 812 -LQSVSTREQESQAAAEKLVQALMERNSELQalrqylggrDSLMSQapiSNQQAEVTPTGRLGKQTDQG-------SMQI 883
Cdd:pfam01576 553 eLEALTQQLEEKAAAYDKLEKTKNRLQQELD---------DLLVDL---DHQRQLVSNLEKKQKKFDQMlaeekaiSARY 620
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 884 PSRDDSTSLTAKED----VSIPRSTLGDLDTVAGLEKELSNAKEELE-LMAKKER--ESQMELSALQSMMAVQEEELQVQ 956
Cdd:pfam01576 621 AEERDRAEAEAREKetraLSLARALEEALEAKEELERTNKQLRAEMEdLVSSKDDvgKNVHELERSKRALEQQVEEMKTQ 700
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 957 aadMESLTRNIQIKED--LIKDLQMQlvdpedipAMERLTQEVLLLREKvasvesQGQEISGNRRQQLLLMLEGLVDERS 1034
Cdd:pfam01576 701 ---LEELEDELQATEDakLRLEVNMQ--------ALKAQFERDLQARDE------QGEEKRRQLVKQVRELEAELEDERK 763
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1035 RLNEALQAERQLYSSLVKFHAHPESSERDRT---------------LQVELEGAQVLRsrlEEVLGRSLERLNRLETLAA 1099
Cdd:pfam01576 764 QRAQAVAAKKKLELDLKELEAQIDAANKGREeavkqlkklqaqmkdLQRELEEARASR---DEILAQSKESEKKLKNLEA 840
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1100 IGGAAAGD---------DTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEML 1170
Cdd:pfam01576 841 ELLQLQEDlaaserarrQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVE 920
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392235 1171 HLRAE------FHQHLEEKR-KAEEELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQM 1226
Cdd:pfam01576 921 QLTTElaaersTSQKSESARqQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQL 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1941-2118 |
7.78e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 7.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1941 ADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH 2020
Cdd:COG1196 241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2021 VSREHSQET---ESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQ 2097
Cdd:COG1196 321 LEEELAELEeelEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
170 180
....*....|....*....|.
gi 2056392235 2098 QCEEKQQLFESLQSELQIYEA 2118
Cdd:COG1196 401 QLEELEEAEEALLERLERLEE 421
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
379-845 |
1.38e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.20 E-value: 1.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 379 EELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEmsyelkcaQESSQKQDGTIQNLKETLKSRER 458
Cdd:TIGR00618 206 LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE--------QLKKQQLLKQLRARIEELRAQEA 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 459 ETEELYQVIEGQNDtmaKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQC 538
Cdd:TIGR00618 278 VLEETQERINRARK---AAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 539 VQFveAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYN--------EIRTQEQNIQHLNHSLSHKE 610
Cdd:TIGR00618 355 IHI--RDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIlqreqatiDTRTSAFRDLQGQLAHAKKQ 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 611 QLLQEFRELLQ--YRDNSDKTLEANEMLLEKLRQRIHDKAVALERAidekfSALEEKEKELRQLRLAVRERDHDLER-LR 687
Cdd:TIGR00618 433 QELQQRYAELCaaAITCTAQCEKLEKIHLQESAQSLKEREQQLQTK-----EQIHLQETRKKAVVLARLLELQEEPCpLC 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 688 DVLSSNEATMQSM------ESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLS 761
Cdd:TIGR00618 508 GSCIHPNPARQDIdnpgplTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 762 ATL-----LCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNK-QVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALME 835
Cdd:TIGR00618 588 NLQnitvrLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVrLHLQQCSQELALKLTALHALQLTLTQERVREHALSI 667
|
490
....*....|
gi 2056392235 836 RNSELQALRQ 845
Cdd:TIGR00618 668 RVLPKELLAS 677
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
383-992 |
1.42e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.90 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 383 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNE--MSYELKCAQESSQKQDGTIQNLKETLKSRERET 460
Cdd:TIGR00606 452 KQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTetLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHT 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 461 EELYQVIEGQNDTMAKLREMLHQSQLG--QLHSSEGTSPAQQQValldlqsalfcsQLEIQKLQRVVRQKERQLADAKQC 538
Cdd:TIGR00606 532 TTRTQMEMLTKDKMDKDEQIRKIKSRHsdELTSLLGYFPNKKQL------------EDWLHSKSKEINQTRDRLAKLNKE 599
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 539 VQFVEAAAH------ESEQQKEASWKHN-------QELRKALQQLQEELQNKSQQlRAWEAEKYN-------EIRTQEQN 598
Cdd:TIGR00606 600 LASLEQNKNhinnelESKEEQLSSYEDKlfdvcgsQDEESDLERLKEEIEKSSKQ-RAMLAGATAvysqfitQLTDENQS 678
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 599 IQHLNHSLSHKEQLLQEFRELLQYRDNSDKT-LEANEMLLEKLRQRIHDKAVALERaideKFSALEEKEKELRQLRLAVR 677
Cdd:TIGR00606 679 CCPVCQRVFQTEAELQEFISDLQSKLRLAPDkLKSTESELKKKEKRRDEMLGLAPG----RQSIIDLKEKEIPELRNKLQ 754
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 678 ERDHDLERLRDVLSSNEATMQS-MESLLRAKGLEVEqlSTTCQNLQWLKEEMETKFSRWQKEQESIiqQLQTSLHDRNKE 756
Cdd:TIGR00606 755 KVNRDIQRLKNDIEEQETLLGTiMPEEESAKVCLTD--VTIMERFQMELKDVERKIAQQAAKLQGS--DLDRTVQQVNQE 830
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 757 VEDlsatllcklgpgqseiAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQ---SVSTREQESQAAAEKLVqal 833
Cdd:TIGR00606 831 KQE----------------KQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSeklQIGTNLQRRQQFEEQLV--- 891
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 834 mERNSELQALRQylggrdslmsqaPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRStlgDLDTVAG 913
Cdd:TIGR00606 892 -ELSTEVQSLIR------------EIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKE---KVKNIHG 955
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 914 LEKELSNAKEELELMAKKERESqmELSALQSMMAVQEEELQVQAADMESLTRNI---QIKEDLIKDLQMQLVDPEDIPAM 990
Cdd:TIGR00606 956 YMKDIENKIQDGKDDYLKQKET--ELNTVNAQLEECEKHQEKINEDMRLMRQDIdtqKIQERWLQDNLTLRKRENELKEV 1033
|
..
gi 2056392235 991 ER 992
Cdd:TIGR00606 1034 EE 1035
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
395-1139 |
2.34e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.51 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 395 TQQSVSDSHLAELQEKIQQTEATNKIlQEKLNEMSYELKCAQESSQKQDGTIQNLKEtlksRERETEELYQVIEGQNDTM 474
Cdd:TIGR00606 197 TQGQKVQEHQMELKYLKQYKEKACEI-RDQITSKEAQLESSREIVKSYENELDPLKN----RLKEIEHNLSKIMKLDNEI 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 475 AKL--REMLHQSQLGQLHssegtspaqqqvalLDLQSALFCSQLEIQKL----QRVVRQKERQLADAKQCVQFVEAAAHE 548
Cdd:TIGR00606 272 KALksRKKQMEKDNSELE--------------LKMEKVFQGTDEQLNDLyhnhQRTVREKERELVDCQRELEKLNKERRL 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 549 SEQQKEaswkhNQELRKALQQLQEELQNksQQLRAWEAEKY-NEIRTQEQNIQHLNHSlshkEQLLQEFRELLQYRDNSD 627
Cdd:TIGR00606 338 LNQEKT-----ELLVEQGRLQLQADRHQ--EHIRARDSLIQsLATRLELDGFERGPFS----ERQIKNFHTLVIERQEDE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 628 --------KTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERD---HDLERLRDVLSSNEAT 696
Cdd:TIGR00606 407 aktaaqlcADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEgssDRILELDQELRKAERE 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 697 MQSME--SLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQL-----QTSLHDRNKEVEDLSATLLCKLG 769
Cdd:TIGR00606 487 LSKAEknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdKMDKDEQIRKIKSRHSDELTSLL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 770 P--GQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL--MERNSELQALRQ 845
Cdd:TIGR00606 567 GyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsQDEESDLERLKE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 846 YLggRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVS-IPRSTLGDLDTVAGLEKELSNAKEE 924
Cdd:TIGR00606 647 EI--EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISdLQSKLRLAPDKLKSTESELKKKEKR 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 925 LELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPE----DIPAMERLTQEVLLL 1000
Cdd:TIGR00606 725 RDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltDVTIMERFQMELKDV 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1001 REKVASVESQGQEISGNRR-QQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERD-RTLQVELEGAQVLRS 1078
Cdd:TIGR00606 805 ERKIAQQAAKLQGSDLDRTvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElKSEKLQIGTNLQRRQ 884
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 1079 RLEEvlgRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEK 1139
Cdd:TIGR00606 885 QFEE---QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK 942
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
494-701 |
2.65e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 494 GTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEE 573
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 574 LQNKSQQLRAWEAEKYNEIRTQEQNIQH-------LNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQrihd 646
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA---- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392235 647 kavALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSME 701
Cdd:COG4942 168 ---ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
637-1095 |
3.89e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 3.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 637 LEKLRQRIHDKAVALERAIDEKFSALEEKEKE------------LRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 704
Cdd:PRK02224 164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQieekeekdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 705 ---RAKGLEVEQLSTTCQNLQWLKEEMEtkfsrwqKEQESI---IQQLQTSLHDRNKEVEDLSATllCKLGPGQSEIAEE 778
Cdd:PRK02224 244 eehEERREELETLEAEIEDLRETIAETE-------REREELaeeVRDLRERLEELEEERDDLLAE--AGLDDADAEAVEA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 779 LCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQEsqaaAEKLVQALMERNSELQALRQYLGGR----DSLM 854
Cdd:PRK02224 315 RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEER----AEELREEAAELESELEEAREAVEDRreeiEELE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 855 SQAPISNQQAEVTPTgRLGKQTDQGSMQIPSRDDS----TSLTAK---------------------------EDVSIPRS 903
Cdd:PRK02224 391 EEIEELRERFGDAPV-DLGNAEDFLEELREERDELrereAELEATlrtarerveeaealleagkcpecgqpvEGSPHVET 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 904 TLGDLDTVAGLEKELSNAKEELELMAKK--------ERESQME-----LSALQSMMAVQEEELQVQAADMESLTRNIQik 970
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERleraedlvEAEDRIErleerREDLEELIAERRETIEEKRERAEELRERAA-- 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 971 edlikDLQMQLVDPEDipAMERLTQEVLLLREKVASVESQGQEISgNRRQQL------LLMLEGLVDERSRLNEALQA-- 1042
Cdd:PRK02224 548 -----ELEAEAEEKRE--AAAEAEEEAEEAREEVAELNSKLAELK-ERIESLerirtlLAAIADAEDEIERLREKREAla 619
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 1043 ----ERQLYSSlvkfhahpESSERDRTLQVE-----LEGAQVLRSRLEEVLGRSLERLNRLE 1095
Cdd:PRK02224 620 elndERRERLA--------EKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELR 673
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
457-845 |
4.59e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 52.05 E-value: 4.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 457 ERETEELYQVIEGQ---NDTMAKLREMLHQSQLgqlhssEGTSPAQQqvALLDLQSALFCSQleiqklQRVVRQKERQLA 533
Cdd:pfam17380 286 ERQQQEKFEKMEQErlrQEKEEKAREVERRRKL------EEAEKARQ--AEMDRQAAIYAEQ------ERMAMERERELE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 534 DAKQcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAwEAEKYNEIRTQEQNIQhlnhslshkEQLL 613
Cdd:pfam17380 352 RIRQ-----EERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQ---------RKIQ 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 614 QEFRELLQYRDNSDktlEANEMLLEKLRqrihdkavaleraidekfsalEEKEKELRQLRLAVRERDHDLERLRDVLSSN 693
Cdd:pfam17380 417 QQKVEMEQIRAEQE---EARQREVRRLE---------------------EERAREMERVRLEEQERQQQVERLRQQEEER 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 694 EATMQSMESLLRAKGLEVEqlsttcQNLQWLKEEMETKfSRWQKEQESIIQQLQTSLHDRnkevedlsatllcklgpgQS 773
Cdd:pfam17380 473 KRKKLELEKEKRDRKRAEE------QRRKILEKELEER-KQAMIEEERKRKLLEKEMEER------------------QK 527
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 774 EIAEELCQRLQRKERmlqdllsdRNKQVLEHEMEIQgllqsvstrEQESQAAAEKLVQALMERNSELqaLRQ 845
Cdd:pfam17380 528 AIYEEERRREAEEER--------RKQQEMEERRRIQ---------EQMRKATEERSRLEAMEREREM--MRQ 580
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
358-690 |
4.96e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 4.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 358 LQELWDDLCEDYLPLRVQpMTEELLKQQKLNSHEttitqqSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQE 437
Cdd:TIGR02168 745 LEERIAQLSKELTELEAE-IEELEERLEEAEEEL------AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 438 SSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREmlhqsqlgqlhssegtspaqqqvALLDLQSALFCSQLE 517
Cdd:TIGR02168 818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA-----------------------EIEELEELIEELESE 874
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 518 IQKLQRVVRQKERQLADAKqcvqfvEAAAHESEQQKEASwKHNQELRKALQQLQEELqNKSQqlraweaEKYNEIrtqEQ 597
Cdd:TIGR02168 875 LEALLNERASLEEALALLR------SELEELSEELRELE-SKRSELRRELEELREKL-AQLE-------LRLEGL---EV 936
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 598 NIQHLNHSLSHKEQLLQEFrellqyrdnsdktLEANEMLLEKLRQRIHDKAVALERAIDE----KFSALEEKEkELRQLR 673
Cdd:TIGR02168 937 RIDNLQERLSEEYSLTLEE-------------AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYE-ELKERY 1002
|
330
....*....|....*..
gi 2056392235 674 LAVRERDHDLERLRDVL 690
Cdd:TIGR02168 1003 DFLTAQKEDLTEAKETL 1019
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
609-863 |
5.31e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 609 KEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIhdkaVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRD 688
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 689 VLSSNEATMQSMESLLRAK-GLEVEQLSTTCQNLQWLKEemetkFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLlck 767
Cdd:COG4942 105 ELAELLRALYRLGRQPPLAlLLSPEDFLDAVRRLQYLKY-----LAPARREQAEELRADLAELAALRAELEAERAEL--- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 768 lgpgqseiaEELCQRLQRKERMLQDLLSDRNKqvlehemeiqgLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYL 847
Cdd:COG4942 177 ---------EALLAELEEERAALEALKAERQK-----------LLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
250
....*....|....*.
gi 2056392235 848 GGRDSLMSQAPISNQQ 863
Cdd:COG4942 237 AAAAERTPAAGFAALK 252
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
369-766 |
5.31e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.13 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 369 YLPLRVQPMTEELLKQQKLNS------------HETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQ 436
Cdd:pfam10174 71 HLQLTIQALQDELRAQRDLNQllqqdfttspvdGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQK 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 437 ESSQKQDGTIQNLKETLKSR------ERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEG----TSPAQQQVALLD 506
Cdd:pfam10174 151 QTLGARDESIKKLLEMLQSKglpkksGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREElhrrNQLQPDPAKTKA 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 507 LQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEA 586
Cdd:pfam10174 231 LQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQT 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 587 E---KYNEIRTQEQNIQHLNHSLSHKEQ---LLQEFRELLQYRdnsdktLEANEMLLEKLRQRIHDKAvaleraiDEKfS 660
Cdd:pfam10174 311 KletLTNQNSDCKQHIEVLKESLTAKEQraaILQTEVDALRLR------LEEKESFLNKKTKQLQDLT-------EEK-S 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 661 ALEEKEKELRQLrLAVRER-----DHDLERLRDVLSSNEATMQSMESllRAKGLEVEQlSTTCQNLQWLKE---EMETKF 732
Cdd:pfam10174 377 TLAGEIRDLKDM-LDVKERkinvlQKKIENLQEQLRDKDKQLAGLKE--RVKSLQTDS-SNTDTALTTLEEalsEKERII 452
|
410 420 430
....*....|....*....|....*....|....
gi 2056392235 733 SRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLC 766
Cdd:pfam10174 453 ERLKEQREREDRERLEELESLKKENKDLKEKVSA 486
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
397-1052 |
6.50e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 6.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 397 QSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQEssqkqdgtiqnLKETLKSRERETEELYQVIEgqndtmAK 476
Cdd:pfam01576 21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE-----------MRARLAARKQELEEILHELE------SR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 477 LREMLHQSQlgQLHSSEgtSPAQQQVALLDlqsalfcSQLEIQKLQRVVRQKERQLADAKqcVQFVEAAAHESEQQkeas 556
Cdd:pfam01576 84 LEEEEERSQ--QLQNEK--KKMQQHIQDLE-------EQLDEEEAARQKLQLEKVTTEAK--IKKLEEDILLLEDQ---- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 557 wkhNQELRKALQQLQEELQNKSQQLrAWEAEKyneirtqeqnIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEML 636
Cdd:pfam01576 147 ---NSKLSKERKLLEERISEFTSNL-AEEEEK----------AKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRK 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 637 LEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRE----RDHDLERLRDVLSSNEATMQSMESLLRAKGLEVE 712
Cdd:pfam01576 213 LEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEetaqKNNALKKIRELEAQISELQEDLESERAARNKAEK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 713 QLSTTCQNLQWLKEEMETKFS--------RWQKEQEsiIQQLQTSLHDRNKEVEdlsaTLLCKLGPGQSEIAEELCQRLQ 784
Cdd:pfam01576 293 QRRDLGEELEALKTELEDTLDttaaqqelRSKREQE--VTELKKALEEETRSHE----AQLQEMRQKHTQALEELTEQLE 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 785 RKERMLQDLlsDRNKQVLEHE-MEIQGLLQSVSTREQESQAAAEKL---VQALMERNSELQALRQYLGGRDSLMsQAPIS 860
Cdd:pfam01576 367 QAKRNKANL--EKAKQALESEnAELQAELRTLQQAKQDSEHKRKKLegqLQELQARLSESERQRAELAEKLSKL-QSELE 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 861 N-----QQAEvTPTGRLGKQTDQGSMQIpsrDDSTSLTAKEdvsiPRSTLGDLDTVAGLEKELSNAKEELELMAKKERES 935
Cdd:pfam01576 444 SvssllNEAE-GKNIKLSKDVSSLESQL---QDTQELLQEE----TRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNV 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 936 QMELSALQSMMAVQEEELQVQAADMESLtrniqikEDLIKDLQMQLvdpedipamERLTQEvllLREKVASVESqgQEIS 1015
Cdd:pfam01576 516 ERQLSTLQAQLSDMKKKLEEDAGTLEAL-------EEGKKRLQREL---------EALTQQ---LEEKAAAYDK--LEKT 574
|
650 660 670
....*....|....*....|....*....|....*..
gi 2056392235 1016 GNRRQQlllmleglvdERSRLNEALQAERQLYSSLVK 1052
Cdd:pfam01576 575 KNRLQQ----------ELDDLLVDLDHQRQLVSNLEK 601
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
400-588 |
7.19e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.98 E-value: 7.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 400 SDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAK-LR 478
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 479 EMLHQ----SQLGQLHSSEGTSPAQQQVALLD-LQSAlfcSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 553
Cdd:COG3883 94 ALYRSggsvSYLDVLLGSESFSDFLDRLSALSkIADA---DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190
....*....|....*....|....*....|....*
gi 2056392235 554 EASWKHNQELRKALQQLQEELQNKSQQLRAWEAEK 588
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAEL 205
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
498-690 |
7.47e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 7.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 498 AQQQVALLD---------LQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQ 568
Cdd:COG4913 247 AREQIELLEpirelaeryAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELD 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 569 QLQEEL-QNKSQQLRAWEAekynEIRTQEQNIQHLNHSLSHKEQLLQEF--------RELLQYRDNSDKTLEAnemlLEK 639
Cdd:COG4913 327 ELEAQIrGNGGDRLEQLER----EIERLERELEERERRRARLEALLAALglplpasaEEFAALRAEAAALLEA----LEE 398
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 640 LRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVL 690
Cdd:COG4913 399 ELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL 449
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-710 |
9.11e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 9.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 498 AQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNK 577
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 578 SQQLRAWEAEKY--------------NEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQR 643
Cdd:COG4942 103 KEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392235 644 IHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLE 710
Cdd:COG4942 183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
408-1202 |
1.04e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.20 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 408 QEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQdgtIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMlhQSQLG 487
Cdd:TIGR00606 198 QGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQ---LESSREIVKSYENELDPLKNRLKEIEHNLSKIMKL--DNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 488 QLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKL----QRVVRQKERQLADAKQCVQFVEAAAHESEQQKEaswkhNQEL 563
Cdd:TIGR00606 273 ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLyhnhQRTVREKERELVDCQRELEKLNKERRLLNQEKT-----ELLV 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 564 RKALQQLQEELQNksQQLRAWEAEKY-NEIRTQEQNIQHLNHSlshkEQLLQEFRELLQYRDNSD--------KTLEANE 634
Cdd:TIGR00606 348 EQGRLQLQADRHQ--EHIRARDSLIQsLATRLELDGFERGPFS----ERQIKNFHTLVIERQEDEaktaaqlcADLQSKE 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 635 MLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERD---HDLERLRDVLSSNEATMQSME--SLLRAKGL 709
Cdd:TIGR00606 422 RLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEgssDRILELDQELRKAERELSKAEknSLTETLKK 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 710 EVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQL-----QTSLHDRNKEVEDLSATLLCKLGPG--QSEIAEELCQR 782
Cdd:TIGR00606 502 EVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdKMDKDEQIRKIKSRHSDELTSLLGYfpNKKQLEDWLHS 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 783 LQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL--MERNSELQALRQYLggRDSLMSQAPIS 860
Cdd:TIGR00606 582 KSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsQDEESDLERLKEEI--EKSSKQRAMLA 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 861 NQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVS-IPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMEL 939
Cdd:TIGR00606 660 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 940 SALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPE----DIPAMERLTQEVLLLREKVASVESQGQEIS 1015
Cdd:TIGR00606 740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltDVTIMERFQMELKDVERKIAQQAAKLQGSD 819
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1016 GNRRQQlllmleglvdersRLNEALQAERQLYSSLVKfhahpESSERDRTLQVELEGAQVLRSRLEEVlgrSLERLNRLE 1095
Cdd:TIGR00606 820 LDRTVQ-------------QVNQEKQEKQHELDTVVS-----KIELNRKLIQDQQEQIQHLKSKTNEL---KSEKLQIGT 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1096 TLAAIGGAAagDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATvetqnpsfsppspmggdsnrclQEEMLHLRAE 1175
Cdd:TIGR00606 879 NLQRRQQFE--EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQE----------------------KEELISSKET 934
|
810 820
....*....|....*....|....*..
gi 2056392235 1176 fhqhleEKRKAEEELKELKAQIEEAGF 1202
Cdd:TIGR00606 935 ------SNKKAQDKVNDIKEKVKNIHG 955
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
390-856 |
1.24e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.59 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 390 HETTITQQSVSDSH-------LAELQEKIQQTEATNKILQEKLNEMSyelkcAQESSQKQDgtIQNLKETLKSRERETEE 462
Cdd:pfam10174 270 REEEIKQMEVYKSHskfmknkIDQLKQELSKKESELLALQTKLETLT-----NQNSDCKQH--IEVLKESLTAKEQRAAI 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 463 LYQVIEGQNDTMAKLREMLH--QSQLGQLHSSEGTspaqQQVALLDLQSALFCS-------QLEIQKLQRVVRQKERQLA 533
Cdd:pfam10174 343 LQTEVDALRLRLEEKESFLNkkTKQLQDLTEEKST----LAGEIRDLKDMLDVKerkinvlQKKIENLQEQLRDKDKQLA 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 534 DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAwEAEKYN-EIRTQEQNIQHLNHSLSHKEQL 612
Cdd:pfam10174 419 GLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLE-ELESLKkENKDLKEKVSALQPELTEKESS 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 613 LQEFRELLQ-------YRDNSDKTLEAN-------EMLLEKLRQRIHDKAVAlERAIDEKFSALEEKEKELRQLRLAVRE 678
Cdd:pfam10174 498 LIDLKEHASslassglKKDSKLKSLEIAveqkkeeCSKLENQLKKAHNAEEA-VRTNPEINDRIRLLEQEVARYKEESGK 576
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 679 RDHDLERLRDVL-------SSNEATMQSMESLLRAKGLEveqLSTTCQNLQWLKEEMETKfsrwqkeqesIIQQLQTSLH 751
Cdd:pfam10174 577 AQAEVERLLGILrevenekNDKDKKIAELESLTLRQMKE---QNKKVANIKHGQQEMKKK----------GAQLLEEARR 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 752 DRNKEVEDLSATLLCKLGPGQSEIAEEL----------CQRLQRKERMLQDLLSDRNKQVLEH-EMEIQGLLQSVStrEQ 820
Cdd:pfam10174 644 REDNLADNSQQLQLEELMGALEKTRQELdatkarlsstQQSLAEKDGHLTNLRAERRKQLEEIlEMKQEALLAAIS--EK 721
|
490 500 510
....*....|....*....|....*....|....*..
gi 2056392235 821 ESQAAAEKLVQALMERNS-ELQALRQYlggRDSLMSQ 856
Cdd:pfam10174 722 DANIALLELSSSKKKKTQeEVMALKRE---KDRLVHQ 755
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
522-717 |
1.37e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.81 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 522 QRVVRQKERQLADAKQCVQFVEAAA-HESE---QQKEASWKHN--QELRKALQQLQEELQNKSQQLRAWE--AEKYNEIR 593
Cdd:PRK02224 523 ELIAERRETIEEKRERAEELRERAAeLEAEaeeKREAAAEAEEeaEEAREEVAELNSKLAELKERIESLEriRTLLAAIA 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 594 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEA--NEMLLEKLRQRiHDKAVALERAIDEKFSALEEKEKELRQ 671
Cdd:PRK02224 603 DAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefDEARIEEARED-KERAEEYLEQVEEKLDELREERDDLQA 681
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2056392235 672 LRLAVRERDHDLERLRDVLSSNEATMQSMESLLRakglEVEQLSTT 717
Cdd:PRK02224 682 EIGAVENELEELEELRERREALENRVEALEALYD----EAEELESM 723
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
652-1024 |
1.60e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.45 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 652 ERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVlssneatmqsmesllRAKGLEVEQLSTTCQNL-QWL----KE 726
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE---------------REKAERYQALLKEKREYeGYEllkeKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 727 EMETKFSRWQKEQESI---IQQLQTSLHDRNKEVEDLSATLlcklgpgqSEIAEELcqrlqrkERMLQDLLSDRNKQVLE 803
Cdd:TIGR02169 234 ALERQKEAIERQLASLeeeLEKLTEEISELEKRLEEIEQLL--------EELNKKI-------KDLGEEEQLRVKEKIGE 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 804 HEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSEL-------QALRQYLGGRDSLMSQapISNQQAEvtptgRLGKQT 876
Cdd:TIGR02169 299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLaeieeleREIEEERKRRDKLTEE--YAELKEE-----LEDLRA 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 877 DQGSMqipsrdDSTSLTAKEDVSIPRSTLGDL-DTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQV 955
Cdd:TIGR02169 372 ELEEV------DKEFAETRDELKDYREKLEKLkREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKED 445
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 956 QAADMESLTRNI-QIKEDLIKDLQMQLVDPEDIPAME-RLTQEVLLLREKVASVESQGQEISGNRRQQLLL 1024
Cdd:TIGR02169 446 KALEIKKQEWKLeQLAADLSKYEQELYDLKEEYDRVEkELSKLQRELAEAEAQARASEERVRGGRAVEEVL 516
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
561-1096 |
2.06e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 561 QELRKALQQLQEELQNKSQQLRAWE-----AEKYNEIRTQEQNIQHLNHSLSH--KEQLLQEFRELLQYRDNSDKTLEAN 633
Cdd:COG4913 231 VEHFDDLERAHEALEDAREQIELLEpirelAERYAAARERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 634 EMLLEKLRQRIHDKAVALERAIDE-KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSS-------NEATMQSMESLLR 705
Cdd:COG4913 311 LERLEARLDALREELDELEAQIRGnGGDRLEQLEREIERLERELEERERRRARLEALLAAlglplpaSAEEFAALRAEAA 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 706 AKGLEVEQLSTTCQNLQWlkeEMETKFSRWQKEQESIIQQLQtSLHDRNKeveDLSATLLcklgpgqsEIAEELCQRLQR 785
Cdd:COG4913 391 ALLEALEEELEALEEALA---EAEAALRDLRRELRELEAEIA-SLERRKS---NIPARLL--------ALRDALAEALGL 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 786 KERMLQ---DLLsdrnkQVLEHEME----IQGLLQSVSTR-----EQESQAAA--------EKLV-QALMERNSELQA-- 842
Cdd:COG4913 456 DEAELPfvgELI-----EVRPEEERwrgaIERVLGGFALTllvppEHYAAALRwvnrlhlrGRLVyERVRTGLPDPERpr 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 843 --------------------LRQYLGGRDSLM---SQAPISNQQAEVTPTGrLGKQtdqgsmqipsrddSTSLTAKEDVS 899
Cdd:COG4913 531 ldpdslagkldfkphpfrawLEAELGRRFDYVcvdSPEELRRHPRAITRAG-QVKG-------------NGTRHEKDDRR 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 900 IPRST--LGD--LDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA--DMESLTRNIQIKEDL 973
Cdd:COG4913 597 RIRSRyvLGFdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeiDVASAEREIAELEAE 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 974 IKDLQmqlvdpEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQqlllmlegLVDERSRLNEALQAERQLYSSLVKF 1053
Cdd:COG4913 677 LERLD------ASSDDLAALEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDL 742
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 2056392235 1054 HAHPESSERDRTLQVELEGAQV--LRSRLEEVLGRSLERLNRLET 1096
Cdd:COG4913 743 ARLELRALLEERFAAALGDAVEreLRENLEERIDALRARLNRAEE 787
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2012-2160 |
2.66e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2012 RRLQAQLSHVSREHS---QETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRL 2088
Cdd:TIGR02168 263 QELEEKLEELRLEVSeleEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 2089 QHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAysldachqipLSSDLSHLVAEVRALRGQLEQ 2160
Cdd:TIGR02168 343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET----------LRSKVAQLELQIASLNNEIER 404
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
337-709 |
3.44e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 49.36 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 337 LNRSLKPLYKTPVSYPLELSDLQELWDdlcEDYLPLRVQpmteelLKQQKLnSHETTITQQSVsdsHLAELQEKIQQTEA 416
Cdd:pfam07111 286 LTRKIQPSDSLEPEFPKKCRSLLNRWR---EKVFALMVQ------LKAQDL-EHRDSVKQLRG---QVAELQEQVTSQSQ 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 417 TNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERET----EELYQVIEGQNDTMAKLREMLHQSQ------- 485
Cdd:pfam07111 353 EQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTasaeEQLKFVVNAMSSTQIWLETTMTRVEqavarip 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 486 ---------LGQLHSSEGTSPAQQQVALLDLQS-----------ALFCSQLEIQKLQRVVRQKERQLAdAKQCVQFVEAA 545
Cdd:pfam07111 433 slsnrlsyaVRKVHTIKGLMARKVALAQLRQEScpppppappvdADLSLELEQLREERNRLDAELQLS-AHLIQQEVGRA 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 546 AHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAW---------EAEKYNEIRTQEQNI--QHLNHSLSHKEQLLQ 614
Cdd:pfam07111 512 REQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVArqgqqesteEAASLRQELTQQQEIygQALQEKVAEVETRLR 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 615 EfrellQYRDNSDKTLEAnemlleklrQRIHDKAVALERAIDEKFSALEEKEKELRqlRLAVRERDHDLERLRDVLSSNE 694
Cdd:pfam07111 592 E-----QLSDTKRRLNEA---------RREQAKAVVSLRQIQHRATQEKERNQELR--RLQDEARKEEGQRLARRVQELE 655
|
410
....*....|....*
gi 2056392235 695 ATMQSMESLLRAKGL 709
Cdd:pfam07111 656 RDKNLMLATLQQEGL 670
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
382-847 |
3.77e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 3.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 382 LKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQD--GTIQNLKETLKSRERE 459
Cdd:COG4717 68 LNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPER 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 460 TEELYQVIEGQNDTMAKLREMlhQSQLGQLhssegtspaQQQVAlldlqsalfcsqleiQKLQRVVRQKERQLADAKQCV 539
Cdd:COG4717 148 LEELEERLEELRELEEELEEL--EAELAEL---------QEELE---------------ELLEQLSLATEEELQDLAEEL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 540 QFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEF--- 616
Cdd:COG4717 202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVlfl 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 617 -------RELLQYRDNSDKTLEANEMLLEKLRQRIHDKAV-----ALERAIDEKFSALEEKEKELRQLRLAVRERDHDLE 684
Cdd:COG4717 282 vlgllalLFLLLAREKASLGKEAEELQALPALEELEEEELeellaALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 685 RLRdvlssNEATMQSMESLLRAKGLEVEqlsttcqnlqwlkEEMETKFSRWQKEQE--SIIQQLQTSLHDRNKEVEDLSA 762
Cdd:COG4717 362 ELQ-----LEELEQEIAALLAEAGVEDE-------------EELRAALEQAEEYQElkEELEELEEQLEELLGELEELLE 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 763 TLlcklgpGQSEIAEELcQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQS--VSTREQESQAAAEKLvQALMERNSEL 840
Cdd:COG4717 424 AL------DEEELEEEL-EELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAEL-RELAEEWAAL 495
|
....*..
gi 2056392235 841 QALRQYL 847
Cdd:COG4717 496 KLALELL 502
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
406-801 |
3.83e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 49.25 E-value: 3.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 406 ELQEKIQQTEATNKILQEKL----------NEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMA 475
Cdd:TIGR04523 364 ELEEKQNEIEKLKKENQSYKqeiknlesqiNDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 476 KLREMLHQSQLGQLHSSEGTSPAQQQVALLdlqsalfcsQLEIQKLQRVVRQKERQLAdakqcvqfveaaahESEQQKEA 555
Cdd:TIGR04523 444 DLTNQDSVKELIIKNLDNTRESLETQLKVL---------SRSINKIKQNLEQKQKELK--------------SKEKELKK 500
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 556 SWKHNQELR---KALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSH---KEQLLQEFRELLQYRDNSDKT 629
Cdd:TIGR04523 501 LNEEKKELEekvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKenlEKEIDEKNKEIEELKQTQKSL 580
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 630 LEANEMLLEKLRQRiHDKAVALERAIDEKFSALEEKEKELRQLRLAVRErdhdlerlrdvLSSNEATMQSMESLLRAkgl 709
Cdd:TIGR04523 581 KKKQEEKQELIDQK-EKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK-----------LSSIIKNIKSKKNKLKQ--- 645
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 710 EVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQT-----SLHDRNKEVEDLSATLLCKLGPGQSEIAEELcQRLQ 784
Cdd:TIGR04523 646 EVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDwlkelSLHYKKYITRMIRIKDLPKLEEKYKEIEKEL-KKLD 724
|
410
....*....|....*..
gi 2056392235 785 RKERMLQDLLSDRNKQV 801
Cdd:TIGR04523 725 EFSKELENIIKNFNKKF 741
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
519-740 |
4.10e-05 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 48.22 E-value: 4.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 519 QKLQRVVRQKERQLADAKqcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEkyneirTQEQN 598
Cdd:pfam09787 14 QKAARILQSKEKLIASLK------EGSGVEGLDSSTALTLELEELRQERDLLREEIQKLRGQIQQLRTE------LQELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 599 IQHLNHSLSHKEQLlQEFRELLQYRDNSDKTLEANemlLEKLRQRIHdkavaleraidekfSALEEKEKELRQLRLAVRE 678
Cdd:pfam09787 82 AQQQEEAESSREQL-QELEEQLATERSARREAEAE---LERLQEELR--------------YLEEELRRSKATLQSRIKD 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 679 RDHDLERLRDVL---SSNEATMQSMESLLR-------AKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQE 740
Cdd:pfam09787 144 REAEIEKLRNQLtskSQSSSSQSELENRLHqltetliQKQTMLEALSTEKNSLVLQLERMEQQIKELQGEGS 215
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
406-742 |
4.19e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.95 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 406 ELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMlHQSQ 485
Cdd:pfam05483 272 QLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAA-HSFV 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 486 LGQLHSS-----EGTSPAQQQVALLDLQSALFCSQL-----EIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQqkea 555
Cdd:pfam05483 351 VTEFEATtcsleELLRTEQQRLEKNEDQLKIITMELqkkssELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQ---- 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 556 swkhnqelrkaLQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYR--DNSDKTLEAN 633
Cdd:pfam05483 427 -----------FEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEklKNIELTAHCD 495
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 634 EMLLE--KLRQRIHDKAVAL-------------ERAIDEKFSALEEKEKELRQLRLAVRER-DHDLERLRDVLSSNEATM 697
Cdd:pfam05483 496 KLLLEnkELTQEASDMTLELkkhqediinckkqEERMLKQIENLEEKEMNLRDELESVREEfIQKGDEVKCKLDKSEENA 575
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2056392235 698 QSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESI 742
Cdd:pfam05483 576 RSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKAL 620
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
517-699 |
4.38e-05 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 46.82 E-value: 4.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 517 EIQKLQRVVRQKERQLADAKQcvqfveaaaheseqqkeaswkHNQELRKALQQLQEELQNKSQQLRAWEAEKY------N 590
Cdd:pfam13851 34 EIAELKKKEERNEKLMSEIQQ---------------------ENKRLTEPLQKAQEEVEELRKQLENYEKDKQslknlkA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 591 EIRTQEQNIQHLNHslsHKEQLLQEFRELLQYRDNsdkTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELR 670
Cdd:pfam13851 93 RLKVLEKELKDLKW---EHEVLEQRFEKVERERDE---LYDKFEAAIQDVQQKTGLKNLLLEKKLQALGETLEKKEAQLN 166
|
170 180 190
....*....|....*....|....*....|...
gi 2056392235 671 QLRLAVRERDHDL----ERLRDVLSSNEATMQS 699
Cdd:pfam13851 167 EVLAAANLDPDALqavtEKLEDVLESKNQLIKD 199
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
577-1199 |
4.61e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 49.05 E-value: 4.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 577 KSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEfrELLQYRDnsdktleanemllekLRQRIHDKAVALERAID 656
Cdd:pfam10174 43 KERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQD--ELRAQRD---------------LNQLLQQDFTTSPVDGE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 657 EKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQ 736
Cdd:pfam10174 106 DKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTR 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 737 K--EQESIIQQLQTSLHDRNKEVEDLSATLLCKL-GPGQSEIAEELCQRLQRKERMLQDLlsDRNKQVLEHEMEI---QG 810
Cdd:pfam10174 186 RiaEAEMQLGHLEVLLDQKEKENIHLREELHRRNqLQPDPAKTKALQTVIEMKDTKISSL--ERNIRDLEDEVQMlktNG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 811 LLQSVSTREQESQAAA------------EKLVQALMERNSELQALRQYLggrDSLMSQAPISNQQAEVTptgrlgkqtdq 878
Cdd:pfam10174 264 LLHTEDREEEIKQMEVykshskfmknkiDQLKQELSKKESELLALQTKL---ETLTNQNSDCKQHIEVL----------- 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 879 gsmqipsrddSTSLTAKEDVSIPRSTLGDLDTVAGLEKE--LSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQ 956
Cdd:pfam10174 330 ----------KESLTAKEQRAAILQTEVDALRLRLEEKEsfLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 957 AADMESLTRNIQIKEDLIKDLQ--MQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQQLllmleglvDERS 1034
Cdd:pfam10174 400 QKKIENLQEQLRDKDKQLAGLKerVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERL--------EELE 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1035 RLNEALQAERQLYSSLvkfhaHPESSERDRTLQVELEGAQVLRSR----------LEEVLGRSLERLNRLETlaAIGGAA 1104
Cdd:pfam10174 472 SLKKENKDLKEKVSAL-----QPELTEKESSLIDLKEHASSLASSglkkdsklksLEIAVEQKKEECSKLEN--QLKKAH 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1105 AGDDTEDTSTEFTDSI---EEEAAHHSHQ------------------QLVKVALEKSLATVETQNPSFSPPSPMGGDSNR 1163
Cdd:pfam10174 545 NAEEAVRTNPEINDRIrllEQEVARYKEEsgkaqaeverllgilrevENEKNDKDKKIAELESLTLRQMKEQNKKVANIK 624
|
650 660 670
....*....|....*....|....*....|....*...
gi 2056392235 1164 CLQEEMlhlRAEFHQHLEEKRKAEEELKE--LKAQIEE 1199
Cdd:pfam10174 625 HGQQEM---KKKGAQLLEEARRREDNLADnsQQLQLEE 659
|
|
| zf-AD |
pfam07776 |
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ... |
4-74 |
4.82e-05 |
|
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.
Pssm-ID: 462262 Cd Length: 75 Bit Score: 43.60 E-value: 4.82e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392235 4 ICRICARELcgNQRRWIFHTASK-LNLQVLLSHVLGKDVPR-DGKAEFACSKCAFMLDRIYRFDTVIARIEAL 74
Cdd:pfam07776 1 VCRLCLDES--DELIPIFDPSDSeKTLAEILEDCTGIELDPnDLLPKQICERCLSKLQEFYSFRERCLESQEL 71
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
380-662 |
5.02e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 48.75 E-value: 5.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 380 ELLKQQKLNSHETTITQQSVSDShLAELQeKIQQTEATNKILQEKLNEMSYELKCAQESsqkqdgtIQNLKETLKSRERE 459
Cdd:PRK11281 46 DALNKQKLLEAEDKLVQQDLEQT-LALLD-KIDRQKEETEQLKQQLAQAPAKLRQAQAE-------LEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 460 TEElyqviegqNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQ---QQVALLDLQSALFCSQLEIQKL------------- 521
Cdd:PRK11281 117 TLS--------TLSLRQLESRLAQtlDQLQNAQNDLAEYNSQlvsLQTQPERAQAALYANSQRLQQIrnllkggkvggka 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 522 ----QRVVRQKERQLADAKQCVQFVEAAAHE------SEQQKEASWKHNQeLRKALQQLQEELQNKsqqlRAWEAEK-YN 590
Cdd:PRK11281 189 lrpsQRVLLQAEQALLNAQNDLQRKSLEGNTqlqdllQKQRDYLTARIQR-LEHQLQLLQEAINSK----RLTLSEKtVQ 263
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392235 591 EIRTQEQNIQHLNHSLSHKEqlLQEFRELlqyrdnSDKTLEANEMLLEKLRQRIH-----DKAVALERAIDEKFSAL 662
Cdd:PRK11281 264 EAQSQDEAARIQANPLVAQE--LEINLQL------SQRLLKATEKLNTLTQQNLRvknwlDRLTQSERNIKEQISVL 332
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
389-1214 |
7.40e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.30 E-value: 7.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 389 SHETTI-TQQSVSDSHLAELQEKIQQTEATnkiLQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQvi 467
Cdd:pfam12128 269 SDETLIaSRQEERQETSAELNQLLRTLDDQ---WKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAA-- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 468 egqndtmaklremLHQSQLGQLHSSegtspaqqqvalLDLQSALFCSQLEiqKLQRVVRQKERQLADAK-QCVQFVEAAA 546
Cdd:pfam12128 344 -------------ADQEQLPSWQSE------------LENLEERLKALTG--KHQDVTAKYNRRRSKIKeQNNRDIAGIK 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 547 HESEQQKEASWKHNQELRKALQQLQEEL--QNKSQQLRAWEAEKYNEIRTQEQNIQhLNHSLSHKEQLLQefrellqyrd 624
Cdd:pfam12128 397 DKLAKIREARDRQLAVAEDDLQALESELreQLEAGKLEFNEEEYRLKSRLGELKLR-LNQATATPELLLQ---------- 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 625 nsdktLEANEMLLEKLRQrihdkavALERAidekFSALEEKEKELRQLRLAvreRDHDLERLRD----VLSSNEATMQSM 700
Cdd:pfam12128 466 -----LENFDERIERARE-------EQEAA----NAEVERLQSELRQARKR---RDQASEALRQasrrLEERQSALDELE 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 701 ESLLRAKGLEVEQLSTTCQNlqwlkeemetkfsrWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLG----------- 769
Cdd:pfam12128 527 LQLFPQAGTLLHFLRKEAPD--------------WEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYgvkldlkridv 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 770 PGQSEIAEELCQRLQRKERMLQDlLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLgg 849
Cdd:pfam12128 593 PEWAASEEELRERLDKAEEALQS-AREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKK-- 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 850 rdslmSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEdvsiprSTLGDLDTVAGLEKELSNAKEEL-ELM 928
Cdd:pfam12128 670 -----NKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKRE------ARTEKQAYWQVVEGALDAQLALLkAAI 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 929 AKKERESQMELSALQSMMAvqeEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLR-----EK 1003
Cdd:pfam12128 739 AARRSGAKAELKALETWYK---RDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRrprlaTQ 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1004 VASVESQGQEISGN----------RRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGA 1073
Cdd:pfam12128 816 LSNIERAISELQQQlarliadtklRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQL 895
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1074 QVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDdtedtstEFTDSIEEEAAHHSHQQLVKVALEKSLATVEtqnPSFSP 1153
Cdd:pfam12128 896 EDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLA-------ETWESLREEDHYQNDKGIRLLDYRKLVPYLE---QWFDV 965
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392235 1154 PSPMGGDSNRCLQEEMLHLRAEFHQHLEE-KRKAEEELKELKAQI-EEAGFSSVSHIRNTMLS 1214
Cdd:pfam12128 966 RVPQSIMVLREQVSILGVDLTEFYDVLADfDRRIASFSRELQREVgEEAFFEGVSESAVRIRS 1028
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
496-679 |
7.87e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.46 E-value: 7.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 496 SPAQQQVALLDLQSALfcsqLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEaswkhnqELRKALQQLQEELQ 575
Cdd:COG1579 1 AMPEDLRALLDLQELD----SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELE-------DLEKEIKRLELEIE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 576 NKSQQLRAWEaEKYNEIRTQEQnIQHLNHSLSH----KEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIhdkaVAL 651
Cdd:COG1579 70 EVEARIKKYE-EQLGNVRNNKE-YEALQKEIESlkrrISDLEDEILELMERIEELEEELAELEAELAELEAEL----EEK 143
|
170 180
....*....|....*....|....*...
gi 2056392235 652 ERAIDEKFSALEEKEKELRQLRLAVRER 679
Cdd:COG1579 144 KAELDEELAELEAELEELEAEREELAAK 171
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1941-2160 |
8.63e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 8.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1941 ADLLEEHLGEIRNLRQRLEesicindRLREQLEHrltstargrgstsnfysqgLESIPQLCNENRVLREDNRRLQAQLSH 2020
Cdd:COG4913 227 ADALVEHFDDLERAHEALE-------DAREQIEL-------------------LEPIRELAERYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2021 VSREHSQ-ETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEvlhfreerlsLQEND----SRLQHKLVLL 2095
Cdd:COG4913 281 LRLWFAQrRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ----------IRGNGgdrlEQLEREIERL 350
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392235 2096 QQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYS------LDACHQI--PLSSDLSHLVAEVRALRGQLEQ 2160
Cdd:COG4913 351 ERELEERERRRARLEALLAALGLPLPASAEEFAALRaeaaalLEALEEEleALEEALAEAEAALRDLRRELRE 423
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1944-2125 |
1.00e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.01 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1944 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLshvsr 2023
Cdd:COG1196 339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----- 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2024 ehsQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQ 2103
Cdd:COG1196 414 ---ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
170 180
....*....|....*....|..
gi 2056392235 2104 QLFESLQSELQIYEALYGNSKK 2125
Cdd:COG1196 491 ARLLLLLEAEADYEGFLEGVKA 512
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
902-1286 |
1.24e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 902 RSTLGDLDTVAGLEKELSNAKEELELMAKKE---RESQMELSALQsmmavqeeeLQVQAADMESLTRNIQIKEDLIKDLQ 978
Cdd:TIGR02168 182 ERTRENLDRLEDILNELERQLKSLERQAEKAeryKELKAELRELE---------LALLVLRLEELREELEELQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 979 MQLVDPEdiPAMERLTQEVLLLREKVASVESQGQEISGNrrqqlllmLEGLVDERSRLNEALQaerqlysslvkfhahpE 1058
Cdd:TIGR02168 253 EELEELT--AELQELEEKLEELRLEVSELEEEIEELQKE--------LYALANEISRLEQQKQ----------------I 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1059 SSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLEtlaaiggaaagddteDTSTEFTDSIEEEAAHHSHQQLVKVALE 1138
Cdd:TIGR02168 307 LRERLANLERQLEELEAQLEELESKLDELAEELAELE---------------EKLEELKEELESLEAELEELEAELEELE 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1139 KSLATvetqnpsfsppspmggdsnrcLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFS-SVSHIRNTMLSLCL 1217
Cdd:TIGR02168 372 SRLEE---------------------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRrERLQQEIEELLKKL 430
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392235 1218 ENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSEsSLQAEFRKLQGKLKNAHNIINLLKEQL 1286
Cdd:TIGR02168 431 EEAELKELQAELEELEEELEELQEELERLEEALEELREELE-EAEQALDAAERELAQLQARLDSLERLQ 498
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
498-1091 |
1.30e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 498 AQQQVALLDLQSALFcSQLEIQKLQRVVRQKERQLADAkqcvqfvEAAAHESEQQKEAswkHNQELRKALQQLQeelQNK 577
Cdd:COG4913 271 LAELEYLRAALRLWF-AQRRLELLEAELEELRAELARL-------EAELERLEARLDA---LREELDELEAQIR---GNG 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 578 SQQLRAWEAEkyneirtqeqnIQHLNHSLSHKEQLLQEFRELLQyrdNSDKTLEANEMLLEKLRQRIHDKAVALERAIDE 657
Cdd:COG4913 337 GDRLEQLERE-----------IERLERELEERERRRARLEALLA---ALGLPLPASAEEFAALRAEAAALLEALEEELEA 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 658 KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRakglevEQLSTTCQNLQWLKE--EMETKFSRW 735
Cdd:COG4913 403 LEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA------EALGLDEAELPFVGEliEVRPEEERW 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 736 QKEQE---------------------SIIQQLQTSLH---------DRNKEVEDLSA-TLLCKL----GPGQSEIAEELC 780
Cdd:COG4913 477 RGAIErvlggfaltllvppehyaaalRWVNRLHLRGRlvyervrtgLPDPERPRLDPdSLAGKLdfkpHPFRAWLEAELG 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 781 QR-----------LQRKER--MLQDLLSDRNKQvleHEMEIQGLLQSV-----STREQ-----ESQAAAEKLVQALMERN 837
Cdd:COG4913 557 RRfdyvcvdspeeLRRHPRaiTRAGQVKGNGTR---HEKDDRRRIRSRyvlgfDNRAKlaaleAELAELEEELAEAEERL 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 838 SELQALRQYLGGRDSLMSQapISNQQAEvtptgrlgkqtdqgsmqipsrddstsltakedvsiprstlgDLDtVAGLEKE 917
Cdd:COG4913 634 EALEAELDALQERREALQR--LAEYSWD-----------------------------------------EID-VASAERE 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 918 LSNAKEELELMakkeRESQMELSALQSMMAVQEEELQVQAADMESLTRNI-----QIK--EDLIKDLQMQLVDPEDIPAm 990
Cdd:COG4913 670 IAELEAELERL----DASSDDLAALEEQLEELEAELEELEEELDELKGEIgrlekELEqaEEELDELQDRLEAAEDLAR- 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 991 erlTQEVLLLREKVAsvesqgQEISGNRRQQlllMLEGLVDERSRLNEAL-QAERQLYSSLVKFHAHPESSERDrtLQVE 1069
Cdd:COG4913 745 ---LELRALLEERFA------AALGDAVERE---LRENLEERIDALRARLnRAEEELERAMRAFNREWPAETAD--LDAD 810
|
650 660
....*....|....*....|..
gi 2056392235 1070 LEGAQVLRSRLEEVLGRSLERL 1091
Cdd:COG4913 811 LESLPEYLALLDRLEEDGLPEY 832
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
554-1247 |
1.77e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.98 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 554 EASWKHNQELRKALQQLQEELQNKSQQlrawEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQyrdnsdkTLEAN 633
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIERLEKFIKR----TENIEELIKEKEKELEEVLREINEISSELPELREELE-------KLEKE 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 634 EMLLEKLRQRIHDKAVALERaIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSneatmqsmeslLRAKGLEVEQ 713
Cdd:PRK03918 230 VKELEELKEEIEELEKELES-LEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-----------LKEKAEEYIK 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 714 LSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQtSLHDRNKEVEDLSATLlcklgpgqSEIAEELcQRLQRKERMLQDL 793
Cdd:PRK03918 298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIK-ELEEKEERLEELKKKL--------KELEKRL-EELEERHELYEEA 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 794 LSDR-NKQVLEHEM------EIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNqqAEV 866
Cdd:PRK03918 368 KAKKeELERLKKRLtgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG--REL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 867 TPTGRLGkqtdqgsmqipsrddstsLTAKEDVSIPRStLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMM 946
Cdd:PRK03918 446 TEEHRKE------------------LLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLK 506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 947 AVQEEELQVQAADMESLTRNIQ-IKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEISGnrrqQLLLM 1025
Cdd:PRK03918 507 ELEEKLKKYNLEELEKKAEEYEkLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLK----ELEEL 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1026 LEGLVDErsrLNEALQAERQLYSSLVKFhahpESSERDrtLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAA 1105
Cdd:PRK03918 583 GFESVEE---LEERLKELEPFYNEYLEL----KDAEKE--LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1106 GDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETqnpsfsppspmggdSNRCLQEEmLHLRAEFHQHLEEKRK 1185
Cdd:PRK03918 654 KKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK--------------TLEKLKEE-LEEREKAKKELEKLEK 718
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392235 1186 AEEELKEL-------KAQIEEAGFSSVSHIRntmlslclenAELKEQMGEAMSDGWEIEEDKEKGEVMV 1247
Cdd:PRK03918 719 ALERVEELrekvkkyKALLKERALSKVGEIA----------SEIFEELTEGKYSGVRVKAEENKVKLFV 777
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
571-845 |
1.80e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 571 QEELQNKSQQLRAWEaEKYNEIRTQEQNIQHLNHSLSHKEQLLQEfrellQYRDNSDKTLEANEMlleklRQRIHDKAVA 650
Cdd:pfam01576 4 EEEMQAKEEELQKVK-ERQQKAESELKELEKKHQQLCEEKNALQE-----QLQAETELCAEAEEM-----RARLAARKQE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 651 LERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMEsllrakgLEVEQLSTTCQNLQ---WLKEE 727
Cdd:pfam01576 73 LEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ-------LEKVTTEAKIKKLEediLLLED 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 728 METKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSatllcKLGPGQSEIAEELCQRLQRKERMLQDL----------LSDR 797
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSLS-----KLKNKHEAMISDLEERLKKEEKGRQELekakrklegeSTDL 220
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2056392235 798 NKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQ 845
Cdd:pfam01576 221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1941-2160 |
2.03e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.97 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1941 ADLLEEHLGEIRNLRQRLEESICINDRLREQLEhRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH 2020
Cdd:TIGR02168 704 RKELEELEEELEQLRKELEELSRQISALRKDLA-RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2021 VSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCE 2100
Cdd:TIGR02168 783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2101 EKQQLFESLQSELQIYEALYGNSKKGLKAYSLDachQIPLSSDLSHLVAEVRALRGQLEQ 2160
Cdd:TIGR02168 863 ELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRELEE 919
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
523-967 |
2.19e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.96 E-value: 2.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 523 RVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELrKALQQLQEELQNKSQQLRAWEAEKYNE---IRTQEQNI 599
Cdd:TIGR00606 169 KALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMEL-KYLKQYKEKACEIRDQITSKEAQLESSreiVKSYENEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 600 QHLNHSLSHKEQLLQEFRELlqyrDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKElrqlrlAVRER 679
Cdd:TIGR00606 248 DPLKNRLKEIEHNLSKIMKL----DNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQR------TVREK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 680 DHDLERLRDVLSSNEATMQsmesLLRAKGLEVEQLSTTCQnlqwLKEEMETKFSRwqkEQESIIQQLQTSL------HDR 753
Cdd:TIGR00606 318 ERELVDCQRELEKLNKERR----LLNQEKTELLVEQGRLQ----LQADRHQEHIR---ARDSLIQSLATRLeldgfeRGP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 754 NKEVE-DLSATLLCKLGPGQSEIAEELCQRLQRKERMLQ---DLLSDRNK---QVLEHEMEI----QGLLQSVSTREQES 822
Cdd:TIGR00606 387 FSERQiKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQeqaDEIRDEKKglgRTIELKKEIlekkQEELKFVIKELQQL 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 823 QAAAEKLV---QALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGR-LGKQTDQGSMQIPSRDDSTSLTAKEDV 898
Cdd:TIGR00606 467 EGSSDRILeldQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRkLDQEMEQLNHHTTTRTQMEMLTKDKMD 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 899 SIPR-------------STLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTR 965
Cdd:TIGR00606 547 KDEQirkiksrhsdeltSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYED 626
|
..
gi 2056392235 966 NI 967
Cdd:TIGR00606 627 KL 628
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1944-2114 |
2.74e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.60 E-value: 2.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1944 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGS-----------------TSNFYSQGLESI--------- 1997
Cdd:TIGR02169 714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENvkselkelearieeleeDLHKLEEALNDLearlshsri 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1998 PQLCNENRVLREDNRRLQAQLSHVSREHSQETEsLREALLSSRSHLQELEKELEHQKVERQQLLEDLR-----------E 2066
Cdd:TIGR02169 794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTL-EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkeeleeeleE 872
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 2067 KQQEVLHFREERLSLQENDSRLQHKLVLLQ---QQCEEKQQLFESLQSELQ 2114
Cdd:TIGR02169 873 LEAALRDLESRLGDLKKERDELEAQLRELErkiEELEAQIEKKRKRLSELK 923
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
548-1021 |
4.16e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.87 E-value: 4.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 548 ESE-QQKEASWKHNQEL----RKALQQLQeeLQNKSQQLRAWEAEKYNEIRTQEQN-IQHL--------NHSLSHKEQLL 613
Cdd:pfam05483 98 EAElKQKENKLQENRKIieaqRKAIQELQ--FENEKVSLKLEEEIQENKDLIKENNaTRHLcnllketcARSAEKTKKYE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 614 QEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQlrlAVRERDHDLERLRDVLSSN 693
Cdd:pfam05483 176 YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK---EINDKEKQVSLLLIQITEK 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 694 EATMQSMESLLRAKGLEVEQLS--TTCQNlQWLKEEMETKfSRWQKEQESIIQQLQTSLHDRNKEVEDL--SATLLCKLG 769
Cdd:pfam05483 253 ENKMKDLTFLLEESRDKANQLEekTKLQD-ENLKELIEKK-DHLTKELEDIKMSLQRSMSTQKALEEDLqiATKTICQLT 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 770 PGQSEIAEELCQ----------RLQRKERMLQDLLSDRNKQVLEHEMEiqglLQSVSTREQESQAAAEKLVQALMERNSE 839
Cdd:pfam05483 331 EEKEAQMEELNKakaahsfvvtEFEATTCSLEELLRTEQQRLEKNEDQ----LKIITMELQKKSSELEEMTKFKNNKEVE 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 840 LQALRQYLGGRDSLMSQapisNQQAEVTPTGRLGKQTDQGSMqIPSRDDSTsltakEDVSIprstlgDLDTVAGLEKELS 919
Cdd:pfam05483 407 LEELKKILAEDEKLLDE----KKQFEKIAEELKGKEQELIFL-LQAREKEI-----HDLEI------QLTAIKTSEEHYL 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 920 NAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQikEDLIKDLQMQlvdpedipamERLTQEVLL 999
Cdd:pfam05483 471 KEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ--EDIINCKKQE----------ERMLKQIEN 538
|
490 500
....*....|....*....|..
gi 2056392235 1000 LREKVASVESQGQEISGNRRQQ 1021
Cdd:pfam05483 539 LEEKEMNLRDELESVREEFIQK 560
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
395-593 |
4.42e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 395 TQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELK--CAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQND 472
Cdd:COG3206 212 EEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGsgPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHP 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 473 TMAKLREmlhqsqlgQLHSSEGTSPAQQQVALLDLQSalfcsqlEIQKLQRVVRQKERQLADAKQcvQFVEAAAHESEQQ 552
Cdd:COG3206 292 DVIALRA--------QIAALRAQLQQEAQRILASLEA-------ELEALQAREASLQAQLAQLEA--RLAELPELEAELR 354
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2056392235 553 KeaswkHNQELrKALQQLQEELQNKSQQLRAWEAEKYNEIR 593
Cdd:COG3206 355 R-----LEREV-EVARELYESLLQRLEEARLAEALTVGNVR 389
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
595-1269 |
4.50e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 4.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 595 QEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEML---LEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQ 671
Cdd:TIGR00618 151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLhgkAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKH 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 672 LRLAVRERDHDLERLRDVLSSNEATmQSMESLLRAKGLEVEQLSTTCQNLQWLKEEME--TKFSRWQKEQESIIQ--QLQ 747
Cdd:TIGR00618 231 LREALQQTQQSHAYLTQKREAQEEQ-LKKQQLLKQLRARIEELRAQEAVLEETQERINraRKAAPLAAHIKAVTQieQQA 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 748 TSLHDRNKEVEDLSATLLCKLGPGQSEIAEelcqrLQRKERMLQDLLSDRNKQVLEHEmeiqgllQSVSTREQESQAAAE 827
Cdd:TIGR00618 310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSS-----IEEQRRLLQTLHSQEIHIRDAHE-------VATSIREISCQQHTL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 828 KlvQALMERNSELQALRQYLGGRDSLMSQapISNQQAEVTPtgrlgkqtdQGSMQIPSRDDSTSLTAKEDVSIPRSTLGD 907
Cdd:TIGR00618 378 T--QHIHTLQQQKTTLTQKLQSLCKELDI--LQREQATIDT---------RTSAFRDLQGQLAHAKKQQELQQRYAELCA 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 908 LdTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVD---- 983
Cdd:TIGR00618 445 A-AITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDidnp 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 984 PEDIPAMERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKF-----HAHPE 1058
Cdd:TIGR00618 524 GPLTRRMQRGEQTYAQLETSEEDVYHQLTSER-KQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNItvrlqDLTEK 602
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1059 SSERDRTLQVELEgaqvlrsRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFT---DSIEEEAAHHSHQQLVKV 1135
Cdd:TIGR00618 603 LSEAEDMLACEQH-------ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTltqERVREHALSIRVLPKELL 675
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1136 AL-EKSLATVETQNPSFSPPSPMGGDSNRCLQEEmlhlraefHQHLEEKRKAEEElkelkaqIEEAGFSSVSHIRNTMLS 1214
Cdd:TIGR00618 676 ASrQLALQKMQSEKEQLTYWKEMLAQCQTLLREL--------ETHIEEYDREFNE-------IENASSSLGSDLAAREDA 740
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392235 1215 LCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQ 1269
Cdd:TIGR00618 741 LNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLRE 795
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
2002-2117 |
5.08e-04 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 43.35 E-value: 5.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2002 NENRVLREDNRRLQAQLSHVSREHsQETESLREALLSSRSHLQEL--EKELEhqkvERQQLLEDLREKQQEVLHFREERL 2079
Cdd:pfam15619 67 EEVRVLRERLRRLQEKERDLERKL-KEKEAELLRLRDQLKRLEKLseDKNLA----EREELQKKLEQLEAKLEDKDEKIQ 141
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2056392235 2080 SLQE----NDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYE 2117
Cdd:pfam15619 142 DLERklelENKSFRRQLAAEKKKHKEAQEEVKILQEEIERLQ 183
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
542-779 |
6.12e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.44 E-value: 6.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 542 VEAAAHESEQQKEASwkhnQELRKALQQLQEELqNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHK-----EQLLQEF 616
Cdd:PRK03918 520 LEKKAEEYEKLKEKL----IKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesvEELEERL 594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 617 RELLQYRD------NSDKTLEANEMLLEKLRqrihDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHdlERLRDVL 690
Cdd:PRK03918 595 KELEPFYNeylelkDAEKELEREEKELKKLE----EELDKAFEELAETEKRLEELRKELEELEKKYSEEEY--EELREEY 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 691 SSNEATMQSMESllRAKGLEvEQLSTTCQNLQWLKEEMEtKFSRWQKEQESIIQQLQtSLHDRNKEVEDLSATL----LC 766
Cdd:PRK03918 669 LELSRELAGLRA--ELEELE-KRREEIKKTLEKLKEELE-EREKAKKELEKLEKALE-RVEELREKVKKYKALLkeraLS 743
|
250
....*....|...
gi 2056392235 767 KLGPGQSEIAEEL 779
Cdd:PRK03918 744 KVGEIASEIFEEL 756
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
610-840 |
6.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 610 EQLLQEFRELLQYRDNSDKTLEANEML--LEKLRQRIHDKAVALE--RAIDEKFS------ALEEKEKELRQLRLAVRER 679
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLepIRELAERYAAARERLAelEYLRAALRlwfaqrRLELLEAELEELRAELARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 680 DHDLERLRDVLSSNEATMQSMESLLRAKGLE-VEQLSttcQNLQWLKEEMETKFSRWQkEQESIIQQLQTSLHDRNKEVE 758
Cdd:COG4913 308 EAELERLEARLDALREELDELEAQIRGNGGDrLEQLE---REIERLERELEERERRRA-RLEALLAALGLPLPASAEEFA 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 759 DLSATLlcklgPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNS 838
Cdd:COG4913 384 ALRAEA-----AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEA 458
|
..
gi 2056392235 839 EL 840
Cdd:COG4913 459 EL 460
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2005-2114 |
6.52e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 6.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2005 RVLREDNRRLQAQL-SHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQE 2083
Cdd:COG1196 216 RELKEELKELEAELlLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295
|
90 100 110
....*....|....*....|....*....|.
gi 2056392235 2084 NDSRLQHKLVLLQQQCEEKQQLFESLQSELQ 2114
Cdd:COG1196 296 ELARLEQDIARLEERRRELEERLEELEEELA 326
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
501-775 |
7.14e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 44.95 E-value: 7.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 501 QVALLDLQSALFCSQLEIQKLQRVVRQKER-QLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEE--LQNK 577
Cdd:COG5185 235 LKGFQDPESELEDLAQTSDKLEKLVEQNTDlRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKkaTESL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 578 SQQLRAWEAEK---------YNEIRTQEQNIQHLNHSLSHKEQLLQEFRE-LLQYRDNSDKTLEANEML--LEKLRQRIH 645
Cdd:COG5185 315 EEQLAAAEAEQeleeskretETGIQNLTAEIEQGQESLTENLEAIKEEIEnIVGEVELSKSSEELDSFKdtIESTKESLD 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 646 DKAVALERAIDEKFSAL-----------EEKEKELRQLR----------------LAVRERDHDLERLRDVLSSNEATMQ 698
Cdd:COG5185 395 EIPQNQRGYAQEILATLedtlkaadrqiEELQRQIEQATssneevskllneliseLNKVMREADEESQSRLEEAYDEINR 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 699 SMESLLRAKGLEVEQLSttcQNLQWLKEEMETKFSRWQKEQESIIQ---QLQTSLHDRNKEVEDLSATLLCKLGPGQSEI 775
Cdd:COG5185 475 SVRSKKEDLNEELTQIE---SRVSTLKATLEKLRAKLERQLEGVRSkldQVAESLKDFMRARGYAHILALENLIPASELI 551
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
540-831 |
8.33e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.89 E-value: 8.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 540 QFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNksqqlraweAEK----YNEIRTQEqnIQHLNHSLSHKEQLLQE 615
Cdd:PLN02939 103 QRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQN---------AEKnillLNQARLQA--LEDLEKILTEKEALQGK 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 616 FREL---LQYRDNSDKT-------LEANEMLLEKLRQRIHDKAV---ALERAIDEKFSALEEKEKELRQLRLAVR----- 677
Cdd:PLN02939 172 INILemrLSETDARIKLaaqekihVEILEEQLEKLRNELLIRGAtegLCVHSLSKELDVLKEENMLLKDDIQFLKaelie 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 678 -----ERDHDLERLRDVLssnEATMQSMESLLRAKGLEVEQLSTTCQNLQWLK-EEMETKFSRWQKEQESIIQQLQTSlH 751
Cdd:PLN02939 252 vaeteERVFKLEKERSLL---DASLRELESKFIVAQEDVSKLSPLQYDCWWEKvENLQDLLDRATNQVEKAALVLDQN-Q 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 752 DRNKEVEDLSATLlckLGPGQSEIAEELCQRLQRKERMLQDLLsdrnkQVLEHEMEIQGLLQSVSTreQESQAAAEKLVQ 831
Cdd:PLN02939 328 DLRDKVDKLEASL---KEANVSKFSSYKVELLQQKLKLLEERL-----QASDHEIHSYIQLYQESI--KEFQDTLSKLKE 397
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
531-847 |
9.61e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.52 E-value: 9.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 531 QLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQlraweaekyneIRTQEQNIQHLNHSLSHKE 610
Cdd:PRK11281 25 AFARAASNGDLPTEADVQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDK-----------IDRQKEETEQLKQQLAQAP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 611 QLLQEF-RELLQYRDNSDKTLEANemlLEKLRQRihdkavALERAIDEKFSALEEKEKELRQLR-LAVRERDHdLERLRD 688
Cdd:PRK11281 94 AKLRQAqAELEALKDDNDEETRET---LSTLSLR------QLESRLAQTLDQLQNAQNDLAEYNsQLVSLQTQ-PERAQA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 689 VLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLqwlkeemetkfsrWQKEQESIiqQLQTSLhdRNKEVEdlSATLLCKL 768
Cdd:PRK11281 164 ALYANSQRLQQIRNLLKGGKVGGKALRPSQRVL-------------LQAEQALL--NAQNDL--QRKSLE--GNTQLQDL 224
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392235 769 GPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMeiqgllQSVSTREQESQAAAEKLVQALMERNSELQalrQYL 847
Cdd:PRK11281 225 LQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEKTV------QEAQSQDEAARIQANPLVAQELEINLQLS---QRL 294
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
379-747 |
9.62e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 9.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 379 EELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMS--------YELKCAQESSQKQDGTIQNLK 450
Cdd:COG4717 116 EELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEeleaelaeLQEELEELLEQLSLATEEELQ 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 451 ETLKSRERETEELYQVIEGQNDTMAKLREmlHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKER 530
Cdd:COG4717 196 DLAEELEELQQRLAELEEELEEAQEELEE--LEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLIL 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 531 QLADAKQCVQFVEAAAHESEQQKEASwkhNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKE 610
Cdd:COG4717 274 TIAGVLFLVLGLLALLFLLLAREKAS---LGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 611 QLLQEFRELLQYRDnsdktLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVL 690
Cdd:COG4717 351 ELLREAEELEEELQ-----LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 691 S--SNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMET--KFSRWQKEQESIIQQLQ 747
Cdd:COG4717 426 DeeELEEELEELEEELEELEEELEELREELAELEAELEQLEEdgELAELLQELEELKAELR 486
|
|
| HAUS5 |
pfam14817 |
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. ... |
1999-2083 |
9.94e-04 |
|
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. The HAUS augmin-like complex contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis.
Pssm-ID: 464332 [Multi-domain] Cd Length: 643 Bit Score: 44.27 E-value: 9.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1999 QLCNENRVLREDNRRLQAQL----------SHVSREHSQETESLREA---------LLSSRSHLQELEKELEHQKVERQQ 2059
Cdd:pfam14817 317 QFLNELAETRSRCQQLQARLqglkdeaeleSLGIGDTSQNDSLLRQVlelelqaagLAASRDTLRSECQQLNKLARERQE 396
|
90 100
....*....|....*....|....
gi 2056392235 2060 LLEDLREKQQEVLHFREERLSLQE 2083
Cdd:pfam14817 397 ALRSLQKKWQRILDFRQLVSELQE 420
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
901-1095 |
1.05e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 901 PRSTLGDLDTVAGLEKELSNAKEELELmAKKERESQMELSALQSMMAVQEEELQVQAADMESLT-----RNIQIKEDLIK 975
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALED-AREQIELLEPIRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 976 DLQMQLVDPEDipAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLvkfHA 1055
Cdd:COG4913 299 ELRAELARLEA--ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL---GL 373
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2056392235 1056 HPESSERD-----RTLQVELEGAQVLRSRLEEVLGRSLERLNRLE 1095
Cdd:COG4913 374 PLPASAEEfaalrAEAAALLEALEEELEALEEALAEAEAALRDLR 418
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
634-845 |
1.34e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 634 EMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRlavreRDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQ 713
Cdd:COG3206 163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 714 LSTTCQNLQWLKEEMETKFSRWQkeQESIIQQLQTSLHDRNKEVEDLSATLlcklGPGQSEIaeelcQRLQRKERMLQDL 793
Cdd:COG3206 238 AEARLAALRAQLGSGPDALPELL--QSPVIQQLRAQLAELEAELAELSARY----TPNHPDV-----IALRAQIAALRAQ 306
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392235 794 LSDRNKQVLEhemEIQGLLQSVSTREQESQAAAEKL---VQALMERNSELQALRQ 845
Cdd:COG3206 307 LQQEAQRILA---SLEAELEALQAREASLQAQLAQLearLAELPELEAELRRLER 358
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
354-1038 |
1.36e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 354 ELSDLQELWDDLCEDY---------LPLRVQPMTEELLKQQKLNSHETTITQQSVSDShLAELQEKIQQTEATNKILQEK 424
Cdd:TIGR02169 252 ELEKLTEEISELEKRLeeieqlleeLNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELEDAEERLAKLEAE 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 425 LNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLhqsqlgqlhssegtspAQQQVAL 504
Cdd:TIGR02169 331 IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL----------------KDYREKL 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 505 LDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKE--------ASWKHNQ--------------- 561
Cdd:TIGR02169 395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEdkaleikkQEWKLEQlaadlskyeqelydl 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 562 -----ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQE---QNIQ--------------------------HLNHSLS 607
Cdd:TIGR02169 475 keeydRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkASIQgvhgtvaqlgsvgeryataievaagnRLNNVVV 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 608 HKEQLLQEFRELLQYRDNSDKT-LEANEMLLEKLRQRIHDKAVALERAI-----DEKFS--------------------- 660
Cdd:TIGR02169 555 EDDAVAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVdlvefDPKYEpafkyvfgdtlvvedieaarr 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 661 ----------------------------------ALEEKEKELRqlrlaVRERDHDLERLRDVLSSNEATMQSMESLLRA 706
Cdd:TIGR02169 635 lmgkyrmvtlegelfeksgamtggsraprggilfSRSEPAELQR-----LRERLEGLKRELSSLQSELRRIENRLDELSQ 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 707 KGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSAtllcKLGPGQSEIA------EELC 780
Cdd:TIGR02169 710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEA----RIEELEEDLHkleealNDLE 785
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 781 QRLQRKE-RMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQaAAEKLVQALMERNSELQALRQylggrdslMSQAPI 859
Cdd:TIGR02169 786 ARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE-YLEKEIQELQEQRIDLKEQIK--------SIEKEI 856
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 860 SNQQAEVTPTGRLGKQTDQGSMQIPSRddstsltakedvsiprstlgdldtVAGLEKELSNAKEELELMAKKERESQMEL 939
Cdd:TIGR02169 857 ENLNGKKEELEEELEELEAALRDLESR------------------------LGDLKKERDELEAQLRELERKIEELEAQI 912
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 940 SALQSMMAVQEEELQVQAADMESLTRNIQIKEDlikdlqmqlvDPEDIPAMERLTQEVLLLREKVASVES------QGQE 1013
Cdd:TIGR02169 913 EKKRKRLSELKAKLEALEEELSEIEDPKGEDEE----------IPEEELSLEDVQAELQRVEEEIRALEPvnmlaiQEYE 982
|
810 820
....*....|....*....|....*
gi 2056392235 1014 ISGNRRQQLLLMLEGLVDERSRLNE 1038
Cdd:TIGR02169 983 EVLKRLDELKEKRAKLEEERKAILE 1007
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
404-752 |
2.22e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.41 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 404 LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLK----ETLKSRERETEElyQVIEGQNdtmAKLRE 479
Cdd:PRK04863 839 LRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNlladETLADRVEEIRE--QLDEAEE---AKRFV 913
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 480 MLHQSQLGQLhssegtspaQQQVALLDlqsalfCSQLEIQKLQRVVRQKERQLADAKQCV----QFVEAAAH----ESEQ 551
Cdd:PRK04863 914 QQHGNALAQL---------EPIVSVLQ------SDPEQFEQLKQDYQQAQQTQRDAKQQAfaltEVVQRRAHfsyeDAAE 978
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 552 QKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAE--KYNEIRTQeqniqhLNHSLSHKEQLLQEFRELLQyrdnsDKT 629
Cdd:PRK04863 979 MLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQlaQYNQVLAS------LKSSYDAKRQMLQELKQELQ-----DLG 1047
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 630 LEANEMLLEKLRQR-----------------IHDKAVALERAIDE---KFSALEEKEKELRQL----------------- 672
Cdd:PRK04863 1048 VPADSGAEERARARrdelharlsanrsrrnqLEKQLTFCEAEMDNltkKLRKLERDYHEMREQvvnakagwcavlrlvkd 1127
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 673 -----RLAVRE------------RDHDLERLRDVLSSNEATMQSMESLLRAKGLEVE-QLSTTCqnLQWLK--------- 725
Cdd:PRK04863 1128 ngverRLHRRElaylsadelrsmSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKvQFYIAV--YQHLRerirqdiir 1205
|
410 420 430
....*....|....*....|....*....|....*
gi 2056392235 726 --------EEMETKFSRWQKEQESIIQQLQTSLHD 752
Cdd:PRK04863 1206 tddpveaiEQMEIELSRLTEELTSREQKLAISSES 1240
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
404-849 |
2.28e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 404 LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQdGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ 483
Cdd:COG3096 308 LVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQ-EKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEA 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 484 SQLgqlhssEGTSPAQQqvaLLDLQSALFCSQLEIQKLQRVVRQKERqladAKQCVQFVEAAAHESEQQkeaswkhnqel 563
Cdd:COG3096 387 AEE------EVDSLKSQ---LADYQQALDVQQTRAIQYQQAVQALEK----ARALCGLPDLTPENAEDY----------- 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 564 rkaLQQLQEELQNKSQQLRAWEaekyneirtqeqniQHLNHSLSHKEQllqeFRELLQyrdnsdktleanemLLEKL--- 640
Cdd:COG3096 443 ---LAAFRAKEQQATEEVLELE--------------QKLSVADAARRQ----FEKAYE--------------LVCKIage 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 641 --RQRIHDKAVAL------ERAIDEKFSALEEKEKELRQLRlavrERDHDLERLRDVLSsneatmqsmesllRAKGLEVE 712
Cdd:COG3096 488 veRSQAWQTARELlrryrsQQALAQRLQQLRAQLAELEQRL----RQQQNAERLLEEFC-------------QRIGQQLD 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 713 QlsttcqnlqwlKEEMETKFSRWQKEQESIIQQLQTSLHDRN---KEVEDLSATL--LCKLGPgqseIAEELCQRLQRKE 787
Cdd:COG3096 551 A-----------AEELEELLAELEAQLEELEEQAAEAVEQRSelrQQLEQLRARIkeLAARAP----AWLAAQDALERLR 615
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2056392235 788 RMLQDLLSDRN------KQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGG 849
Cdd:COG3096 616 EQSGEALADSQevtaamQQLLEREREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGG 683
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1944-2118 |
2.34e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 2.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1944 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSR 2023
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2024 EHSQETESLREALLSSRSHLQELEKELEHQKV---ERQQLLEDLREKQQEV----LHFREERLSLQENDSRLQHKLVLLQ 2096
Cdd:COG4942 112 ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYlapARREQAEELRADLAELaalrAELEAERAELEALLAELEEERAALE 191
|
170 180
....*....|....*....|..
gi 2056392235 2097 QQCEEKQQLFESLQSELQIYEA 2118
Cdd:COG4942 192 ALKAERQKLLARLEKELAELAA 213
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
1995-2112 |
2.49e-03 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 42.44 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1995 ESIPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDL---------- 2064
Cdd:pfam09787 61 EEIQKLRGQIQQLRTELQELEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQEELRYLEEELrrskatlqsr 140
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 2065 -REKQQEVLHFREERLSLQENDS---RLQHKLVLLQQQCEEKQQLFESLQSE 2112
Cdd:pfam09787 141 iKDREAEIEKLRNQLTSKSQSSSsqsELENRLHQLTETLIQKQTMLEALSTE 192
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
396-813 |
3.03e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.02 E-value: 3.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 396 QQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQdGTIQNLKETLKSRERETEELYQVIEGQNDTMA 475
Cdd:PRK04863 301 QLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQ-EKIERYQADLEELEERLEEQNEVVEEADEQQE 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 476 KLREMLHQSQLGQLHSSEGTSPAQQQvalLDLQsalfcsqleiQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEa 555
Cdd:PRK04863 380 ENEARAEAAEEEVDELKSQLADYQQA---LDVQ----------QTRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLE- 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 556 swkhnqELRKALQQLQEELQNKSQQLRAweAEKYNEIRTQE-QNIQHLNHSLShKEQLLQEFRELL-QYRD--NSDKTLE 631
Cdd:PRK04863 446 ------EFQAKEQEATEELLSLEQKLSV--AQAAHSQFEQAyQLVRKIAGEVS-RSEAWDVARELLrRLREqrHLAEQLQ 516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 632 ANEMLLEKLRQRIHDKAvALERAIDE---KFSALEEKEKELRQLRlavRERDHDLERLRDVLSSNEAtmqsmesllRAKG 708
Cdd:PRK04863 517 QLRMRLSELEQRLRQQQ-RAERLLAEfckRLGKNLDDEDELEQLQ---EELEARLESLSESVSEARE---------RRMA 583
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 709 LEVEQlsttcQNLQWLKEEMETKFSRWQKEQESiIQQLQTSLHDrnkEVEDlsatllcklgpgqSEIAEELCQRLQRKER 788
Cdd:PRK04863 584 LRQQL-----EQLQARIQRLAARAPAWLAAQDA-LARLREQSGE---EFED-------------SQDVTEYMQQLLERER 641
|
410 420
....*....|....*....|....*...
gi 2056392235 789 MLQ---DLLSDRNKQVLEhemEIQGLLQ 813
Cdd:PRK04863 642 ELTverDELAARKQALDE---EIERLSQ 666
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
499-679 |
3.10e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.58 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 499 QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEelqnKS 578
Cdd:COG4372 56 QAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQ----QR 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 579 QQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEK 658
Cdd:COG4372 132 KQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIES 211
|
170 180
....*....|....*....|.
gi 2056392235 659 FSALEEKEKELRQLRLAVRER 679
Cdd:COG4372 212 LPRELAEELLEAKDSLEAKLG 232
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
660-865 |
3.37e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 660 SALEEKEKELRQLRlavrerdHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEq 739
Cdd:COG4942 20 DAAAEAEAELEQLQ-------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 740 esiIQQLQTSLHDRNKEVEDLSATL--LCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVleheMEIQGLLQSVST 817
Cdd:COG4942 92 ---IAELRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQA----EELRADLAELAA 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2056392235 818 REQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAE 865
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA 212
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
519-668 |
5.17e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 5.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 519 QKLQRVVRQKERQL-ADAKQCVQFVEAAAHE--SEQQKEASWKHN--QELRKALQQLQEELQNKSQQLRaweaEKYNEIR 593
Cdd:PRK12704 38 EEAKRILEEAKKEAeAIKKEALLEAKEEIHKlrNEFEKELRERRNelQKLEKRLLQKEENLDRKLELLE----KREEELE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 594 TQEQNIQHLNHSLSHKEQLLQEFR-----ELLQYrdnSDKTL-EANEMLLEKLRQRIHDKAVALERAIDEKfsALEEKEK 667
Cdd:PRK12704 114 KKEKELEQKQQELEKKEEELEELIeeqlqELERI---SGLTAeEAKEILLEKVEEEARHEAAVLIKEIEEE--AKEEADK 188
|
.
gi 2056392235 668 E 668
Cdd:PRK12704 189 K 189
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
408-861 |
6.01e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.05 E-value: 6.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 408 QEKIQQTEATNKILQEKLNEmsyELKCAQESSQKQDGTIQNLKETLKSRE--RETEELYQVIEGQN--DTMAKLREMLHQ 483
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKAD---EAKKKAEEAKKADEAKKKAEEAKKAEEakKKAEEAKKADEAKKkaEEAKKADEAKKK 1491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 484 SQLGQLHSSEGTSPAQQQVALLDLQSALfcsqlEIQKLQRVVRQKERQLADAKQCVQFVEAAaheSEQQKEASWKHNQEL 563
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKADEAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKA---DELKKAEELKKAEEK 1563
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 564 RKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEfrELLQYRDNSDKTLEANEMLLEKLRQR 643
Cdd:PTZ00121 1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA--EEAKIKAEELKKAEEEKKKVEQLKKK 1641
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 644 IHD---KAVALERAIDE-KFSALEEKEKELRQLRLA--VRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEV------ 711
Cdd:PTZ00121 1642 EAEekkKAEELKKAEEEnKIKAAEEAKKAEEDKKKAeeAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaeel 1721
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 712 ----EQLSTTCQNLQWLKEEMETKFSRWQKEQE--SIIQQLQTSLHDRNKEVEDLSATLLcklgpgQSEIAEELCQRLQR 785
Cdd:PTZ00121 1722 kkaeEENKIKAEEAKKEAEEDKKKAEEAKKDEEekKKIAHLKKEEEKKAEEIRKEKEAVI------EEELDEEDEKRRME 1795
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2056392235 786 KERMLQDLLSdrNKQVLEhEMEIQGLLQSVSTREQESQAAAEKLVQALMERNsELQALRQYLGGRDSLMSQAPISN 861
Cdd:PTZ00121 1796 VDKKIKDIFD--NFANII-EGGKEGNLVINDSKEMEDSAIKEVADSKNMQLE-EADAFEKHKFNKNNENGEDGNKE 1867
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1942-2108 |
6.17e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 6.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1942 DLLEEHLGEIRNLRQRLEESIcinDRLREQLEHRLTSTAR-GRGSTSNFYSQGlESIPQLCNENRVLREDNRRLQAQLSH 2020
Cdd:COG4942 79 AALEAELAELEKEIAELRAEL---EAQKEELAELLRALYRlGRQPPLALLLSP-EDFLDAVRRLQYLKYLAPARREQAEE 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2021 VsREHSQETESLREALLSSRSHLQELEKE-------LEHQKVERQQLLEDLREKQQEvlhFREERLSLQENDSRLQHKLV 2093
Cdd:COG4942 155 L-RADLAELAALRAELEAERAELEALLAEleeeraaLEALKAERQKLLARLEKELAE---LAAELAELQQEAEELEALIA 230
|
170
....*....|....*
gi 2056392235 2094 LLQQQCEEKQQLFES 2108
Cdd:COG4942 231 RLEAEAAAAAERTPA 245
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
463-625 |
6.29e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.49 E-value: 6.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 463 LYQVIEGQNDTMAKLREMLhqSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFV 542
Cdd:PRK09039 44 LSREISGKDSALDRLNSQI--AELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGEL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 543 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAekyneiRTQEQNIQ------HLNHSLSHKEQLLQ-- 614
Cdd:PRK09039 122 AQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK------RDRESQAKiadlgrRLNVALAQRVQELNry 195
|
170
....*....|....*..
gi 2056392235 615 --EF----RELLQYRDN 625
Cdd:PRK09039 196 rsEFfgrlREILGDREG 212
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
395-865 |
6.47e-03 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 42.09 E-value: 6.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 395 TQQSVSDSHLAELQEKIQQteatnkiLQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEgQNDTM 474
Cdd:PRK10246 419 AEQRPLRQRLVALHGQIVP-------QQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICE-QEARI 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 475 AKLREMLHQSQLGQLHSSEGTS--PAQQQVALLDLQSalfcSQLEIQKLQRVVRQ-KERQLADAKQcvqfVEAAAHESEQ 551
Cdd:PRK10246 491 KDLEAQRAQLQAGQPCPLCGSTshPAVEAYQALEPGV----NQSRLDALEKEVKKlGEEGAALRGQ----LDALTKQLQR 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 552 QKEASwkhnQELRKALQQLQEELQNKSQQLraweaekyNEIRTQEQNIQH-LNHSLSHKEQLLQefrelLQYRDNSDKTL 630
Cdd:PRK10246 563 DESEA----QSLRQEEQALTQQWQAVCASL--------NITLQPQDDIQPwLDAQEEHERQLRL-----LSQRHELQGQI 625
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 631 EANEMLLEKLRQRIHDKAVALERAI----------DEKFSALEEKEKEL-----RQLRL-AVRERDHDLERLRDVLSSNE 694
Cdd:PRK10246 626 AAHNQQIIQYQQQIEQRQQQLLTALagyaltlpqeDEEASWLATRQQEAqswqqRQNELtALQNRIQQLTPLLETLPQSD 705
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 695 ATMQSMESLLRAKGLEV--EQLSTTCQnLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDrnkeveDLSATLLCKLGPGQ 772
Cdd:PRK10246 706 DLPHSEETVALDNWRQVheQCLSLHSQ-LQTLQQQDVLEAQRLQKAQAQFDTALQASVFD------DQQAFLAALLDEET 778
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 773 SEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQeSQAAAEKLVQALME---RNSEL-QALRQYLG 848
Cdd:PRK10246 779 LTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQ-IQQELAQLAQQLREnttRQGEIrQQLKQDAD 857
|
490 500
....*....|....*....|
gi 2056392235 849 GRD---SLMSQAPISNQQAE 865
Cdd:PRK10246 858 NRQqqqALMQQIAQATQQVE 877
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
637-764 |
7.35e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 637 LEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQS-------------MESL 703
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkeyealqkeIESL 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392235 704 LRAKGL----------EVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATL 764
Cdd:COG1579 102 KRRISDledeilelmeRIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
676-1297 |
7.61e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 7.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 676 VRERDHDLERLRDVLSSNEATMQSMESLLRAkglEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLH---- 751
Cdd:pfam15921 80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQ---SVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHelea 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 752 ----------DRNKEVEDLSATLLCKLGPgqseiaeelcqrLQRKERMLQDLLSDRNKQVLEHE----MEIQGLLQSVST 817
Cdd:pfam15921 157 akclkedmleDSNTQIEQLRKMMLSHEGV------------LQEIRSILVDFEEASGKKIYEHDsmstMHFRSLGSAISK 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 818 REQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAP-------ISNQQAEVTPTGRLGKQTDQGSMQIPSRDDST 890
Cdd:pfam15921 225 ILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHqdrieqlISEHEVEITGLTEKASSARSQANSIQSQLEII 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 891 SLTAKEDVSIPRSTLGDLD-TVAGLEKELSNAKeelelmakkeRESQMELSALQSMMAVQEEELQVQAADMESLTRNIQI 969
Cdd:pfam15921 305 QEQARNQNSMYMRQLSDLEsTVSQLRSELREAK----------RMYEDKIEELEKQLVLANSELTEARTERDQFSQESGN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 970 KEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVdersrlnEALQAE--RQLY 1047
Cdd:pfam15921 375 LDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALL-------KAMKSEcqGQME 447
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1048 SSLVKFHAHPESSERDRTLQVELEGA-QVLRSRLEEVLGR--SLERLNRLETLAAIGGAAAGDDTEDTSTEFT------- 1117
Cdd:pfam15921 448 RQMAAIQGKNESLEKVSSLTAQLESTkEMLRKVVEELTAKkmTLESSERTVSDLTASLQEKERAIEATNAEITklrsrvd 527
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1118 ------DSIEEEAAHHSHQQLVKVALEKSLA----TVETQNPSFSPPSPMGGDSNRClQEEMLHLRAEFHQHLEEKRKAE 1187
Cdd:pfam15921 528 lklqelQHLKNEGDHLRNVQTECEALKLQMAekdkVIEILRQQIENMTQLVGQHGRT-AGAMQVEKAQLEKEINDRRLEL 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 1188 EELKELKAQIEeagfSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEdkEKGEVMVETVVTKEGLseSSLQAEFRK 1267
Cdd:pfam15921 607 QEFKILKDKKD----AKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ--ERDQLLNEVKTSRNEL--NSLSEDYEV 678
|
650 660 670
....*....|....*....|....*....|
gi 2056392235 1268 LQGKLKNAHNIINLLKEQLVLSSKEGNSKL 1297
Cdd:pfam15921 679 LKRNFRNKSEEMETTTNKLKMQLKSAQSEL 708
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
407-642 |
7.71e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 7.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 407 LQEKIQQTEATNKILQEKLNEMSYELKCAQESsqkqdgtIQNLKETLK--SRERETEELYQVIEGQNDTMAKLREMLH-- 482
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAA-------LEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAea 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 483 QSQLGQLhssegtspaQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQcvQFVEA--AAHESEQQKEASwkhN 560
Cdd:COG3206 239 EARLAAL---------RAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSA--RYTPNhpDVIALRAQIAAL---R 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 561 QELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNhslshkeQLLQEFRELLQYRDNSDKTLeanEMLLEKL 640
Cdd:COG3206 305 AQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELP-------ELEAELRRLEREVEVARELY---ESLLQRL 374
|
..
gi 2056392235 641 RQ 642
Cdd:COG3206 375 EE 376
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
535-796 |
8.51e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 8.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 535 AKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEI-RTQEQ-------------NIQ 600
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIeELTDEllnlvmdiedpsaALN 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 601 HLNHSLSHKEQLLQEF-RELLQYRDNSD-----KTLEANEMLLEKLRQRIHDKAVALErAIDEKFSALEEKEKELRQLRL 674
Cdd:PHA02562 259 KLNTAAAKIKSKIEQFqKVIKMYEKGGVcptctQQISEGPDRITKIKDKLKELQHSLE-KLDTAIDELEEIMDEFNEQSK 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 675 AVRErdhdlerLRDVLSSNEATMQSMESllRAKGLEVEqlsttcqnlqwlkeemetkfsrwqkeqesiIQQLQTSLHDRN 754
Cdd:PHA02562 338 KLLE-------LKNKISTNKQSLITLVD--KAKKVKAA------------------------------IEELQAEFVDNA 378
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2056392235 755 KEVEDLSATLLcKLGPGQSEIAEELCQRLqrkerMLQDLLSD 796
Cdd:PHA02562 379 EELAKLQDELD-KIVKTKSELVKEKYHRG-----IVTDLLKD 414
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
2002-2111 |
8.57e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.89 E-value: 8.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 2002 NENRVLREDNRRLQAQLSHVsREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLL----------EDLREKQQEV 2071
Cdd:pfam13851 54 QENKRLTEPLQKAQEEVEEL-RKQLENYEKDKQSLKNLKARLKVLEKELKDLKWEHEVLEqrfekvererDELYDKFEAA 132
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2056392235 2072 LHFREERLSLQENdsRLQHKLVLLQQQCEEKQ-QLFESLQS 2111
Cdd:pfam13851 133 IQDVQQKTGLKNL--LLEKKLQALGETLEKKEaQLNEVLAA 171
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
517-717 |
8.61e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 8.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 517 EIQKLQRVVRQKERQLADAKQ---CVQFVEAAAHESEQQKEAswkhNQELRKALQQLQEeLQNKSQQLRAWEAEKYNEIR 593
Cdd:COG3206 183 QLPELRKELEEAEAALEEFRQkngLVDLSEEAKLLLQQLSEL----ESQLAEARAELAE-AEARLAALRAQLGSGPDALP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 594 TQEQN--IQHLNHSLSHKEQLLQEfrELLQYRDNS------DKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEK 665
Cdd:COG3206 258 ELLQSpvIQQLRAQLAELEAELAE--LSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQ 335
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2056392235 666 EKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMesLLRAKGLEVEQLSTT 717
Cdd:COG3206 336 LAQLEARLAELPELEAELRRLEREVEVARELYESL--LQRLEEARLAEALTV 385
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
651-845 |
8.91e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 8.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 651 LERAIDEKFSALEEK----EKELRQLRLAVRERDHDLERLRdvlSSNEATMQSMESllrakGLEVEQLSTTCQNLQWLKE 726
Cdd:COG3206 162 LEQNLELRREEARKAleflEEQLPELRKELEEAEAALEEFR---QKNGLVDLSEEA-----KLLLQQLSELESQLAEARA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392235 727 EMEtkfsrwqkEQESIIQQLQTSLHDRNKEVEDLSatllcklgpgQSEIAEELCQRLQRKERMLQDLLS---DRNKQVLE 803
Cdd:COG3206 234 ELA--------EAEARLAALRAQLGSGPDALPELL----------QSPVIQQLRAQLAELEAELAELSArytPNHPDVIA 295
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2056392235 804 HEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQ 845
Cdd:COG3206 296 LRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLA 337
|
|
| |
