|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
269-1067 |
1.00e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.95 E-value: 1.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 269 HLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLH 348
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 349 QSQlgqlhssegTSPAQQQVALLDLQSALFCSQLEIQKLqrvvrqkERQLADAKQCVQFVEAAAHESEQQKEASWKHNQE 428
Cdd:TIGR02168 313 NLE---------RQLEELEAQLEELESKLDELAEELAEL-------EEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 429 LRKALQQLQEELQNKSQQLRAWEaekyNEIRTQEQNIQHLNHSLshkEQLLQEFRELLQYRDNSDktLEANEMLLEKLRQ 508
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLN----NEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAE--LKELQAELEELEE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 509 RIHDKAVALERAIdekfSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQ 588
Cdd:TIGR02168 448 ELEELQEELERLE----EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 589 WLKEEMETKfSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEElcqrlqrkermlqDLLSDRNKQVL 668
Cdd:TIGR02168 524 VLSELISVD-EGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPL-------------DSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 669 EHEM--EIQGLLQSVSTREqESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAE-VTPTGRLGKQTDQG 745
Cdd:TIGR02168 590 DREIlkNIEGFLGVAKDLV-KFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDlVRPGGVITGGSAKT 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 746 SMQIPSRDdSTSLTAKEDVSIPRSTLGDLDT-VAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA 824
Cdd:TIGR02168 669 NSSILERR-REIEELEEKIEELEEKIAELEKaLAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 825 DMESLTRNIQIKEDLIKDLQMQLvdpedipamERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDERSRLNE 904
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEELEERL---------EEAEEELAEAEAEIEELEAQIEQLK-EELKALREALDELRAELTLLNE 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 905 ALQAERQLYSSLVKFHAHPESSERDRT------------LQVELEGAQVLRSRLEEVLGRSLERLNRLET---LAAIGGA 969
Cdd:TIGR02168 818 EAANLRERLESLERRIAATERRLEDLEeqieelsediesLAAEIEELEELIEELESELEALLNERASLEEalaLLRSELE 897
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 970 AAGDDTEDTSTEFTDSieEEAAHHSHQQLVKVALEKSLATVETQNpsfsppspmggdsnrcLQE---EMLHLRAEFHQHL 1046
Cdd:TIGR02168 898 ELSEELRELESKRSEL--RRELEELREKLAQLELRLEGLEVRIDN----------------LQErlsEEYSLTLEEAEAL 959
|
810 820
....*....|....*....|....*.
gi 2056392186 1047 EEKR-----KAEEELKELKAQIEEAG 1067
Cdd:TIGR02168 960 ENKIeddeeEARRRLKRLENKIKELG 985
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
79-708 |
6.66e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 6.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 79 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQ------NEAELRRQFEERQQETEHVY---ELLENKIQLLQEESRLAK 149
Cdd:TIGR02168 271 ELRLEVSELEEEIEELQKELYALANEISRLEQQkqilreRLANLERQLEELEAQLEELEsklDELAEELAELEEKLEELK 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 150 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQvkpDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLL 229
Cdd:TIGR02168 351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKV---AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 230 HLLEEPTSMEVQPMTEELLKQQklnshETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQD 309
Cdd:TIGR02168 428 KKLEEAELKELQAELEELEEEL-----EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 310 GTIQNLKETLKSRER------------ETEELYQ--------------VIEGQNDTMAKLrEMLHQSQLG---------- 353
Cdd:TIGR02168 503 GFSEGVKALLKNQSGlsgilgvlseliSVDEGYEaaieaalggrlqavVVENLNAAKKAI-AFLKQNELGrvtflpldsi 581
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 354 -----------QLHSSEG---------TSPAQQQVALLDLQSALFCSQ-----LEIQKLQR------------------- 389
Cdd:TIGR02168 582 kgteiqgndreILKNIEGflgvakdlvKFDPKLRKALSYLLGGVLVVDdldnaLELAKKLRpgyrivtldgdlvrpggvi 661
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 390 ---------VVRQKERQLADAKQCVQFVEAAAHESEQQkeaswkhnqelRKALQQLQEELQNKSQQLRAWEAEKYNEI-- 458
Cdd:TIGR02168 662 tggsaktnsSILERRREIEELEEKIEELEEKIAELEKA-----------LAELRKELEELEEELEQLRKELEELSRQIsa 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 459 --------RTQEQNIQHLNHSLSHK-EQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDkavaLERAIDEKFSALE 529
Cdd:TIGR02168 731 lrkdlarlEAEVEQLEERIAQLSKElTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ----LKEELKALREALD 806
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 530 EKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESII 609
Cdd:TIGR02168 807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLE 886
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 610 QQlqtsLHDRNKEVEDLSATLLcklgpgqsEIAEELcQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQ 689
Cdd:TIGR02168 887 EA----LALLRSELEELSEELR--------ELESKR-SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL 953
|
730
....*....|....*....
gi 2056392186 690 AAAEKLVQALMERNSELQA 708
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARR 972
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
417-1140 |
3.34e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 3.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 417 QQKEASWKHNQELRKALQQLQEELQNKSQ-------QLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYR 489
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQeleekleELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 490 DNSDKTLEANEMLLEKLRQRIHDKAVALERAIDE---KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSM 566
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAEELAELEEKLEElkeELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 567 ESLLRAK----GLEVEQLSTTCQNLQWLKEEMETKFSRWQ-KEQESIIQQLQTSLHDRNKEVEDLSATLlcKLGPGQSEI 641
Cdd:TIGR02168 395 IASLNNEierlEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELERLEEAL--EELREELEE 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 642 AEEL-------CQRLQRKERMLQDLL------SDRNKQVLEHEMEIQGLLQSVSTR-------EQESQAAAEKLVQALME 701
Cdd:TIGR02168 473 AEQAldaaereLAQLQARLDSLERLQenlegfSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALGGRLQAVVV 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 702 RNSE-----LQALRQYLGGRDSLMsqAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSiprSTLGDLDT 776
Cdd:TIGR02168 553 ENLNaakkaIAFLKQNELGRVTFL--PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS---YLLGGVLV 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 777 VAGLEKELSNAKEELE----------------LMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLI 840
Cdd:TIGR02168 628 VDDLDNALELAKKLRPgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 841 KDLQMQLVDPEDIPamERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKfh 920
Cdd:TIGR02168 708 EELEEELEQLRKEL--EELSRQISALRKDLARLEAEVEQLE-ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA-- 782
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 921 ahpESSERDRTLQVELEGAQVLRSRLEEVLGRsLERLNRLETLAAIGGAAAGDDTEDTSTEFTDsIEEEAAHHSHQQLvk 1000
Cdd:TIGR02168 783 ---EIEELEAQIEQLKEELKALREALDELRAE-LTLLNEEAANLRERLESLERRIAATERRLED-LEEQIEELSEDIE-- 855
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1001 vALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGfSSVSHIRNTMLS 1080
Cdd:TIGR02168 856 -SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR-EKLAQLELRLEG 933
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1081 LCLENAELKEQmgeaMSDGWEIEEDkekgevMVETVVTKEGLSESSLQAEFRKLQGKLKN 1140
Cdd:TIGR02168 934 LEVRIDNLQER----LSEEYSLTLE------EAEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
199-908 |
2.95e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.86 E-value: 2.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 199 QRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEpTSMEVQPMTEELLKQQK-LNSH-------ETTITQQSVSDSHL 270
Cdd:TIGR02168 236 ELREELEELQEELKEAEEELEELTAELQELEEKLEE-LRLEVSELEEEIEELQKeLYALaneisrlEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 271 ----AELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREM 346
Cdd:TIGR02168 315 erqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 347 L--HQSQLGQLhSSEGTSPAQQQVALLDLQSALFCSQLE--IQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEAS 422
Cdd:TIGR02168 395 IasLNNEIERL-EARLERLEDRRERLQQEIEELLKKLEEaeLKELQAELEELEEELEELQEELERLEEALEELREELEEA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 423 WKHNQELR----------KALQQLQEELQNKSQQLRAWEAEKyneiRTQEQNIQHLNHSLSHKEQLLQE----FRELLQY 488
Cdd:TIGR02168 474 EQALDAAErelaqlqarlDSLERLQENLEGFSEGVKALLKNQ----SGLSGILGVLSELISVDEGYEAAieaaLGGRLQA 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 489 --RDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDlERLRDVLSS-------- 558
Cdd:TIGR02168 550 vvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD-PKLRKALSYllggvlvv 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 559 ---NEATMQSMES------------LLRAKGLEVEQLSTTCQNLQWLKEEMEtkfsrwqkEQESIIQQLQTSLHDRNKEV 623
Cdd:TIGR02168 629 ddlDNALELAKKLrpgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIE--------ELEEKIEELEEKIAELEKAL 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 624 EDLSATLlcklgpgqSEIAEELCQRLQRKERMLQDlLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERN 703
Cdd:TIGR02168 701 AELRKEL--------EELEEELEQLRKELEELSRQ-ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 704 SELQALRQYLGGRDSLMSQAP------------ISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTL 771
Cdd:TIGR02168 772 EAEEELAEAEAEIEELEAQIEqlkeelkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 772 GDLdtvAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPE 851
Cdd:TIGR02168 852 EDI---ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 852 DipAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQA 908
Cdd:TIGR02168 929 L--RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
69-616 |
3.57e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 3.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 69 QALRDFEKniELKVEVESLK-RELQDKKQHLDKTWADVENLNSQNEAELrRQFEERQQETEHVYELLENKIQLLQEESRL 147
Cdd:COG1196 216 RELKEELK--ELEAELLLLKlRELEAELEELEAELEELEAELEELEAEL-AELEAELEELRLELEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 148 AKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVP----GDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSR 223
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEeeleELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 224 EKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQE 303
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 304 SSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQ---------QQVALLDLQ 374
Cdd:COG1196 453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALllaglrglaGAVAVLIGV 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 375 SALFCSQLEIQKLQRVVRQKERQLADAKQCVQFV--EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEA 452
Cdd:COG1196 533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 453 EKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKE 532
Cdd:COG1196 613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 533 KELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKG--LEVEQLSTTCQNLQWLKEEMETKFSRwqKEQESIIQ 610
Cdd:COG1196 693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEReeLLEELLEEEELLEEEALEELPEPPDL--EELERELE 770
|
....*.
gi 2056392186 611 QLQTSL 616
Cdd:COG1196 771 RLEREI 776
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
79-710 |
4.98e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 4.98e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 79 ELKVEVESLKR---------ELQDKKQHLDKtWADVENLNSQNEAelRRQFEERQQETEHVYELLENKIQLLQEEsrlak 149
Cdd:TIGR02168 197 ELERQLKSLERqaekaerykELKAELRELEL-ALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEK----- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 150 neaarmaaLVEAEKEcNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRdkrieeLNQSLAAQERLVEQLSREKQQLL 229
Cdd:TIGR02168 269 --------LEELRLE-VSELEEEIEELQKELYALANEISRLEQQKQILRER------LANLERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 230 HLLEEPTSMEVQpmTEELLKQQKLNSHEttitqqsvsdshLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQD 309
Cdd:TIGR02168 334 ELAEELAELEEK--LEELKEELESLEAE------------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 310 GTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEgtspAQQQVALLDLQSALFCSQLEIQKLQR 389
Cdd:TIGR02168 400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----EELQEELERLEEALEELREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 390 VVRQKERQLADAKQCVQFVEA--AAHESEQQKEASWKHNQELRKALQQ-------------------LQEELQ-----NK 443
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERlqENLEGFSEGVKALLKNQSGLSGILGvlselisvdegyeaaieaaLGGRLQavvveNL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 444 SQQLRAWEAEKYNEI--------------------RTQEQNIQHLNHSLSHKEQLLQEFRELLQYR-------DNSD--- 493
Cdd:TIGR02168 556 NAAKKAIAFLKQNELgrvtflpldsikgteiqgndREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvDDLDnal 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 494 ---KTLEANEML-------------------------------LEKLRQRI---HDKAVALERAIDEKFSALEEKEKELR 536
Cdd:TIGR02168 636 elaKKLRPGYRIvtldgdlvrpggvitggsaktnssilerrreIEELEEKIeelEEKIAELEKALAELRKELEELEEELE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 537 QLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSL 616
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 617 HDRNKEVEDLSA-----TLLCKLGPGQSEIAEELCQRLQRKERMLQDlLSDRNKQVLEHEMEIQGLLQSVSTREQESQAA 691
Cdd:TIGR02168 796 EELKALREALDElraelTLLNEEAANLRERLESLERRIAATERRLED-LEEQIEELSEDIESLAAEIEELEELIEELESE 874
|
730
....*....|....*....
gi 2056392186 692 AEKLVQALMERNSELQALR 710
Cdd:TIGR02168 875 LEALLNERASLEEALALLR 893
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
317-886 |
2.63e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.66 E-value: 2.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 317 ETLKsRERETEELYQVIEgqndtmAKLREMLHQSQLGQLHSsegtspAQQQVALLDLQSALfcSQLEIQKLQRVVRQKER 396
Cdd:COG1196 203 EPLE-RQAEKAERYRELK------EELKELEAELLLLKLRE------LEAELEELEAELEE--LEAELEELEAELAELEA 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 397 QLADAKQcvqfveaAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKE 476
Cdd:COG1196 268 ELEELRL-------ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 477 QLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSAL---EEKEKELRQLRLAVRERDHDLERLR 553
Cdd:COG1196 341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALraaAELAAQLEELEEAEEALLERLERLE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 554 DVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCK 633
Cdd:COG1196 421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 634 ---LGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTR-EQESQAAAEKLVQALMER------- 702
Cdd:COG1196 501 adyEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEdDEVAAAAIEYLKAAKAGRatflpld 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 703 ----------NSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLG 772
Cdd:COG1196 581 kiraraalaaALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 773 DLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA-DMESLTRNIQIKEDLIKDLQMQLVDPE 851
Cdd:COG1196 661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAeEERLEEELEEEALEEQLEAEREELLEE 740
|
570 580 590
....*....|....*....|....*....|....*
gi 2056392186 852 DIPAMERLTQEVLLLREKVASVESQGQEISGNRRQ 886
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLERE 775
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
57-731 |
5.48e-12 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 71.54 E-value: 5.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 57 LRAFEKPPQVQTQALRDFEKNIELKVEVESLKRELQ--------------DKKQHLDKTWADVEN--------------- 107
Cdd:TIGR00618 169 LMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQlltlctpcmpdtyhERKQVLEKELKHLREalqqtqqshayltqk 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 108 LNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKnEAARMAALVEAEKECNLELSEKLKGVtknwedvpgdQ 187
Cdd:TIGR00618 249 REAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRAR-KAAPLAAHIKAVTQIEQQAQRIHTEL----------Q 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 188 VKPDQYTEALAQRDKRIEElNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQ-----PMTEELLKQQKLNSHETTITQ 262
Cdd:TIGR00618 318 SKMRSRAKLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIscqqhTLTQHIHTLQQQKTTLTQKLQ 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 263 QSVSD-SHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQviegqndtma 341
Cdd:TIGR00618 397 SLCKElDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ---------- 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 342 KLREMLHQSQLGQLHSSEGTSPAQQQVALLdlqsalfcsqLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEA 421
Cdd:TIGR00618 467 SLKEREQQLQTKEQIHLQETRKKAVVLARL----------LELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQT 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 422 SWKHNQELRKALQQLQEELqNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDN-SDKTLEANE 500
Cdd:TIGR00618 537 YAQLETSEEDVYHQLTSER-KQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEaEDMLACEQH 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 501 MLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRD----VLSSNEATMQSMESLLRAKGLE 576
Cdd:TIGR00618 616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVlpkeLLASRQLALQKMQSEKEQLTYW 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 577 VEQLStTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRN-------KEVEDLSATLLCKLGPGQSEIAEELCQRL 649
Cdd:TIGR00618 696 KEMLA-QCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREdalnqslKELMHQARTVLKARTEAHFNNNEEVTAAL 774
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 650 QR--KERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTR----EQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQA 723
Cdd:TIGR00618 775 QTgaELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEipsdEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKY 854
|
....*...
gi 2056392186 724 PISNQQAE 731
Cdd:TIGR00618 855 EECSKQLA 862
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
384-1067 |
9.44e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.74 E-value: 9.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 384 IQKLQRVVRQKERQLA----DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEkyneIR 459
Cdd:COG1196 188 LERLEDILGELERQLEplerQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAE----LA 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 460 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLR 539
Cdd:COG1196 264 ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 540 LAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTtcQNLQWLKEEMETkfsrwQKEQESIIQQLQTSLHDR 619
Cdd:COG1196 344 EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--ELLEALRAAAEL-----AAQLEELEEAEEALLERL 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 620 NKEVEDLSATLLcklgpgQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL 699
Cdd:COG1196 417 ERLEEELEELEE------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 700 MERNSELQALRQYLGGRDSLMSQAPISnQQAEVTPTGRLGKQTDQGsmqiPSRDDSTSLTAKEDVSIPRSTLGDLDTVAG 779
Cdd:COG1196 491 ARLLLLLEAEADYEGFLEGVKAALLLA-GLRGLAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 780 LEKELSNAKEELELMAKKERESQMELSALQSMMA--VQEEELQVQAADMESLTRNIQIKEDLIKDlqmqlvDPEDIPAME 857
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAavDLVASDLREADARYYVLGDTLLGRTLVAA------RLEAALRRA 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 858 RLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSslvkfhahpESSERDRTLQVELE 937
Cdd:COG1196 640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE---------EALLAEEEEERELA 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 938 GAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAhhshqqlvkvalekslatvetqnpsf 1017
Cdd:COG1196 711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-------------------------- 764
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1018 sppspmggdsnrclqeemlhlraefhqhleekrkAEEELKELKAQIEEAG 1067
Cdd:COG1196 765 ----------------------------------LERELERLEREIEALG 780
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
428-698 |
9.08e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 9.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 428 ELRKALQQLQEE---------LQNKSQQLRAWEaeKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDnsdKTLEA 498
Cdd:TIGR02169 195 EKRQQLERLRRErekaeryqaLLKEKREYEGYE--LLKEKEALERQKEAIERQLASLEEELEKLTEEISELE---KRLEE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 499 NEMLLEKLRQRIHDKAVALERAIDEKfsaLEEKEKELRQLRLAVRERDHDLERLrdvlssnEATMQSMESLLRAKGLEVE 578
Cdd:TIGR02169 270 IEQLLEELNKKIKDLGEEEQLRVKEK---IGELEAEIASLERSIAEKERELEDA-------EERLAKLEAEIDKLLAEIE 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 579 QLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQtSLHDRNKEVEDLSATLLCKLGPGQSEIAEelcqrLQRKERMLQD 658
Cdd:TIGR02169 340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELE-EVDKEFAETRDELKDYREKLEKLKREINE-----LKRELDRLQE 413
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2056392186 659 LLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQA 698
Cdd:TIGR02169 414 ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
149-556 |
6.29e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 6.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 149 KNEAARMAALVEAEKECNLELSEKLKGVtknwedvpgdQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQL 228
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAEL----------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 229 LHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQsvsDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 308
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEA---EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 309 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREmlhqsqlgqlhssegtspaqqqvALLDLQSALFCSQLEIQKLQ 388
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAA-----------------------EIEELEELIEELESELEALL 879
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 389 RVVRQKERQLADAKQCVQFVEAAAHESEQQKEAswkhNQELRKALQQLQEELQNKSQQLraweaekyneirtqEQNIQHL 468
Cdd:TIGR02168 880 NERASLEEALALLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGL--------------EVRIDNL 941
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 469 NHSLSHKEQLLQEFrellqyrdnsdktLEANEMLLEKLRQRIHDKAVALERAIDE----KFSALEEKEkELRQLRLAVRE 544
Cdd:TIGR02168 942 QERLSEEYSLTLEE-------------AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYE-ELKERYDFLTA 1007
|
410
....*....|..
gi 2056392186 545 RDHDLERLRDVL 556
Cdd:TIGR02168 1008 QKEDLTEAKETL 1019
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
52-722 |
1.22e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 63.83 E-value: 1.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 52 VQTYSLRAFEKPPQVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHV 130
Cdd:TIGR00618 223 VLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERiNRARKAAPLAAHIKAV 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 131 YELLENKIQLLQE-ESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVkpDQYTEALAQRDKRIEELNQ 209
Cdd:TIGR00618 303 TQIEQQAQRIHTElQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAH--EVATSIREISCQQHTLTQH 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 210 SLAAQER---LVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKI 286
Cdd:TIGR00618 381 IHTLQQQkttLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 287 LQE---KLNEMSYELKCAQESSQKQDGT----------IQNLKETLKSRERETE-ELYQVIEGQNDTMAKLREMLHQSQL 352
Cdd:TIGR00618 461 LQEsaqSLKEREQQLQTKEQIHLQETRKkavvlarlleLQEEPCPLCGSCIHPNpARQDIDNPGPLTRRMQRGEQTYAQL 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 353 GQlhsSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKA 432
Cdd:TIGR00618 541 ET---SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 433 LQQLQEELQNksqqlraweaekYNEIRTQEQNIQHLNHSLSHKEQLLQEfrelLQYRDNSDKTLEANEMLLEKL--RQRI 510
Cdd:TIGR00618 618 LRKLQPEQDL------------QDVRLHLQQCSQELALKLTALHALQLT----LTQERVREHALSIRVLPKELLasRQLA 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 511 HDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTcqNLQWL 590
Cdd:TIGR00618 682 LQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQART--VLKAR 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 591 KEEMETKFSRWQKEQESI--IQQLQTSLHDRNKEVEDLSATLLCKLgpgqSEIAEELCQRLQrkERMLQDLLSDRNKQVL 668
Cdd:TIGR00618 760 TEAHFNNNEEVTAALQTGaeLSHLAAEIQFFNRLREEDTHLLKTLE----AEIGQEIPSDED--ILNLQCETLVQEEEQF 833
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2056392186 669 EHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQ 722
Cdd:TIGR00618 834 LSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
424-1160 |
1.93e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 63.45 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 424 KHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQ---------------------HLNHSLSHKEQLLQEF 482
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKaleyyqlkekleleeeyllylDYLKLNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 483 RELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEAT 562
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 563 MQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHD----RNKEVEDLSATLLCKLGPGQ 638
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeserLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 639 SEiaeelcQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQ---ALRQYLGG 715
Cdd:pfam02463 406 EA------QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKkseDLLKETQL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 716 RDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEdvsiPRSTLGDLDTVAGLEKELSNAKEELELMA 795
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS----AHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 796 KK------ERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQmQLVDPEDIPAMERLTQEVLLLREK 869
Cdd:pfam02463 556 TAdeveerQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK-ATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 870 VASVESQGQEISGNRRQQlllMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEV 949
Cdd:pfam02463 635 TKLKESAKAKESGLRKGV---SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 950 LGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNpsfsppSPMGGDSNR 1029
Cdd:pfam02463 712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL------AEEREKTEK 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1030 CLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIRNTMLSlcLENAELKEQMGEAMSDGWEIEEDKEKG 1109
Cdd:pfam02463 786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELE--ELALELKEEQKLEKLAEEELERLEEEI 863
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 2056392186 1110 EVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIinlLKEQLVLSSKEGN 1160
Cdd:pfam02463 864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEE---KKELEEESQKLNL 911
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
257-872 |
2.00e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 257 ETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEmsyelkcAQESSQKQDGTIQNLKETLKSRERETEELyqviegq 336
Cdd:COG1196 256 EELEAELAELEAELEELRLELEELELELEEAQAEEYE-------LLAELARLEQDIARLEERRRELEERLEEL------- 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 337 ndtmaklremlhqsqlgqlhssegtspaqqqvalldlqsalfcsQLEIQKLQRVVRQKERQLADAkqcvqfvEAAAHESE 416
Cdd:COG1196 322 --------------------------------------------EEELAELEEELEELEEELEEL-------EEELEEAE 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 417 QQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL 496
Cdd:COG1196 351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 497 EANEMLLEKLRQRihdkavalERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAkgle 576
Cdd:COG1196 431 AELEEEEEEEEEA--------LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE---- 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 577 veqlsttcqnlqwLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVED-LSATLLCKLGPGQSEIAEELCQRLQRKERM 655
Cdd:COG1196 499 -------------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAaYEAALEAALAAALQNIVVEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 656 LQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEkLVQALMERNSELQALRQYLGGRDSLmSQAPISNQQAEVTPT 735
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDL-VASDLREADARYYVLGDTLLGRTLV-AARLEAALRRAVTLA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 736 GRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSmmAVQ 815
Cdd:COG1196 644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE--EEL 721
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 816 EEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVAS 872
Cdd:COG1196 722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
75-539 |
2.13e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.73 E-value: 2.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 75 EKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEaELRRQFEERQQETEHVYELLENKIQLLQEesrlAKNEaar 154
Cdd:TIGR04523 225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN-KIKKQLSEKQKELEQNNKKIKELEKQLNQ----LKSE--- 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 155 maaLVEAEKECNLELSEKLKGVTKNWEDvpgdqvKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEE 234
Cdd:TIGR04523 297 ---ISDLNNQKEQDWNKELKSELKNQEK------KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 235 PTSmEVQPMTEEllKQQKLNSHETTITQQSvsdshlaELQEKIQQTEATNKILQEKlnemsyelkcaqessqkqdgtIQN 314
Cdd:TIGR04523 368 KQN-EIEKLKKE--NQSYKQEIKNLESQIN-------DLESKIQNQEKLNQQKDEQ---------------------IKK 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 315 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLdlqsalfcsQLEIQKLQRVVRQK 394
Cdd:TIGR04523 417 LQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL---------SRSINKIKQNLEQK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 395 ERQLAdakqcvqfveaaahESEQQKEASWKHNQELR---KALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHS 471
Cdd:TIGR04523 488 QKELK--------------SKEKELKKLNEEKKELEekvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE 553
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392186 472 LSH---KEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRiHDKAVALERAIDEKFSALEEKEKELRQLR 539
Cdd:TIGR04523 554 LKKenlEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEEKEKKISSLEKELEKAK 623
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
79-631 |
7.42e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.19 E-value: 7.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 79 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQ----------NEAELRRQFEERQQETEHVYELLeNKIQLLQEESRLA 148
Cdd:TIGR04523 79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEikndkeqknkLEVELNKLEKQKKENKKNIDKFL-TEIKKKEKELEKL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 149 KNEAARMAALVEA-EKECNLELSEKLKgVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQ 227
Cdd:TIGR04523 158 NNKYNDLKKQKEElENELNLLEKEKLN-IQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEK 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 228 LLHLLEEptsmevqpmteellKQQKLNSHETTITQQSVSDSH-LAELQEKIQQTEATNKILQEKLNEMS-YELKCAQESS 305
Cdd:TIGR04523 237 KQQEINE--------------KTTEISNTQTQLNQLKDEQNKiKKQLSEKQKELEQNNKKIKELEKQLNqLKSEISDLNN 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 306 QKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREmlhqsQLGQLHSSegtspaqqqvaLLDLQSALFCSQLEIQ 385
Cdd:TIGR04523 303 QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNE-----QISQLKKE-----------LTNSESENSEKQRELE 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 386 KLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQ---LRAWEAEKYNEIRTQE 462
Cdd:TIGR04523 367 EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEierLKETIIKNNSEIKDLT 446
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 463 QNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANemlLEKLRQRIHDKAVALERAIDEKfSALEEKEKELRQLRLAV 542
Cdd:TIGR04523 447 NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN---LEQKQKELKSKEKELKKLNEEK-KELEEKVKDLTKKISSL 522
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 543 RERDHDLE----RLRDVLSSNEATMQSMESLLRAKGLEvEQLSTTCQNLQWLKEEmETKFSRWQKEQESIIQQLQTSLHD 618
Cdd:TIGR04523 523 KEKIEKLEsekkEKESKISDLEDELNKDDFELKKENLE-KEIDEKNKEIEELKQT-QKSLKKKQEEKQELIDQKEKEKKD 600
|
570
....*....|...
gi 2056392186 619 RNKEVEDLSATLL 631
Cdd:TIGR04523 601 LIKEIEEKEKKIS 613
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
67-583 |
7.83e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.21 E-value: 7.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 67 QTQALRDFEKNIELKVEVESLKReLQDKKQHLDKTWADVENLNSQNE-AELRRQ--------FEERQQETEHvyelLENK 137
Cdd:PRK02224 185 QRGSLDQLKAQIEEKEEKDLHER-LNGLESELAELDEEIERYEEQREqARETRDeadevleeHEERREELET----LEAE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 138 IQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEE-LNQSLAAQER 216
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDrLEECRVAAQA 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 217 LVEQLSREKQQLLHLLEEPTsmEVQPMTEELlkQQKLNSHETTITQQSvsdSHLAELQEKIQQTEATNKILQEKLNEMSY 296
Cdd:PRK02224 340 HNEEAESLREDADDLEERAE--ELREEAAEL--ESELEEAREAVEDRR---EEIEELEEEIEELRERFGDAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 297 ELKCAQESSQKQDGTIQNLKETLKS---RERETEELYQ------------------VIEGQNDTMAKLREMLHQSQLGQ- 354
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTareRVEEAEALLEagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVe 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 355 -----LHSSEGTSPAQQQVALLDLQSALFCSQLEIQKlqRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQEL 429
Cdd:PRK02224 493 eveerLERAEDLVEAEDRIERLEERREDLEELIAERR--ETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEA 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 430 RKALQQLQEELQNKSQQLRAWE--AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEA--NEMLLEK 505
Cdd:PRK02224 571 REEVAELNSKLAELKERIESLEriRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefDEARIEE 650
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2056392186 506 LRQRiHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRakglEVEQLSTT 583
Cdd:PRK02224 651 ARED-KERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALEALYD----EAEELESM 723
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
239-553 |
1.79e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.08 E-value: 1.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 239 EVQPMTEELLKQQKLnsHETTITQQSVSDSHLAELQEKIQQteatnkiLQEKLNEMSYELKCAQESSQKQDGTIQNLKET 318
Cdd:TIGR02169 675 ELQRLRERLEGLKRE--LSSLQSELRRIENRLDELSQELSD-------ASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 319 LKSRERETEELYQVIEGQNDTMAKLREMLH--QSQLGQLHSSEGTSPAQQQVALL---------------DLQSALFCSQ 381
Cdd:TIGR02169 746 LSSLEQEIENVKSELKELEARIEELEEDLHklEEALNDLEARLSHSRIPEIQAELskleeevsriearlrEIEQKLNRLT 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 382 LEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAekynEIRTQ 461
Cdd:TIGR02169 826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA----QLREL 901
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 462 EQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLE----------ANEMLLEKLRQRIHDKAVALE-------RAIDE- 523
Cdd:TIGR02169 902 ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedeeipEEELSLEDVQAELQRVEEEIRalepvnmLAIQEy 981
|
330 340 350
....*....|....*....|....*....|....*
gi 2056392186 524 -----KFSALEEKEKELRQLRLAVRERDHDLERLR 553
Cdd:TIGR02169 982 eevlkRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| Olduvai |
pfam06758 |
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the ... |
1581-1650 |
4.66e-08 |
|
Olduvai domain; This domain formerly known as DUF1220 or NBPF domain has been renamed as the Olduvai domain. It is found highly duplicated in the human lineage.
Pssm-ID: 429104 [Multi-domain] Cd Length: 68 Bit Score: 51.65 E-value: 4.66e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1581 DHKSEKDQaglEPLALRLSRELQEKEKViEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACS 1650
Cdd:pfam06758 1 DEEEEEDQ---EPLAPRLSRELPEVEEQ-EVPQDSLDECYLTPSVLPDLSDSYQPYRSTIFSFEEQQVSS 66
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
121-1065 |
8.66e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 8.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 121 EERQQETEHVYELLENKIQLLQEEsrlaKNEAARMAALVEAEKEcnLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 200
Cdd:TIGR02169 183 EENIERLDLIIDEKRQQLERLRRE----REKAERYQALLKEKRE--YEGYELLKEKEALERQKEAIERQLASLEEELEKL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 201 DKRIEELNQSLAAQERLVEQLSREkqqllhlleeptsmeVQPMTEELLKQQKLNSHETTITQQSVSDShLAELQEKIQQT 280
Cdd:TIGR02169 257 TEEISELEKRLEEIEQLLEELNKK---------------IKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELEDA 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 281 EATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLhqsqlgqlhsseg 360
Cdd:TIGR02169 321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL------------- 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 361 tspAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEaswkhnqELRKALQQLQEEL 440
Cdd:TIGR02169 388 ---KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKE-------DKALEIKKQEWKL 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 441 QNKSQQLRAWEAEKYNeirtQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERa 520
Cdd:TIGR02169 458 EQLAADLSKYEQELYD----LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS- 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 521 IDEKFSALEEKEKELRqLRLAVRERDHDLERLRDVLSSNEATMQSMESL--LRAKGLEVEQLSTT-----CQNLQWLKEE 593
Cdd:TIGR02169 533 VGERYATAIEVAAGNR-LNNVVVEDDAVAKEAIELLKRRKAGRATFLPLnkMRDERRDLSILSEDgvigfAVDLVEFDPK 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 594 METKFsrWQKEQESIIqqlqtslhdrnkeVEDLsatllcklgpgqseiaeELCQRLQRKERMLQ---DLLSDRNKQVLEH 670
Cdd:TIGR02169 612 YEPAF--KYVFGDTLV-------------VEDI-----------------EAARRLMGKYRMVTlegELFEKSGAMTGGS 659
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 671 EMEIQGLLQSVSTREQESQAAAEklvqaLMERNSELQALRQYLGGRDSLMSQAPISNQQAEvtptgrlgkqtdqgsmqip 750
Cdd:TIGR02169 660 RAPRGGILFSRSEPAELQRLRER-----LEGLKRELSSLQSELRRIENRLDELSQELSDAS------------------- 715
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 751 srddstsltakedvsiprstlgdldtvagleKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLT 830
Cdd:TIGR02169 716 -------------------------------RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE 764
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 831 RNIQIKEDLIKDLQMQLVDPEDIPAMER---LTQEVLLLREKVASVESQGQEISG--NRRQQLLLMLEGLVDERSRLNEA 905
Cdd:TIGR02169 765 ARIEELEEDLHKLEEALNDLEARLSHSRipeIQAELSKLEEEVSRIEARLREIEQklNRLTLEKEYLEKEIQELQEQRID 844
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 906 LQAERqlysslVKFHAHPESSE-RDRTLQVELEGAQV----LRSRLEEVLGRSLERLNRLETLaaiggaaagddtEDTST 980
Cdd:TIGR02169 845 LKEQI------KSIEKEIENLNgKKEELEEELEELEAalrdLESRLGDLKKERDELEAQLREL------------ERKIE 906
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 981 EFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSnRCLQEEMLHLRAEFH----------QHLEEKR 1050
Cdd:TIGR02169 907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRalepvnmlaiQEYEEVL 985
|
970
....*....|....*
gi 2056392186 1051 KAEEELKELKAQIEE 1065
Cdd:TIGR02169 986 KRLDELKEKRAKLEE 1000
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
80-695 |
9.49e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.82 E-value: 9.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 80 LKVEVESLKRELQDKKQHLDKTwADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ------------------LL 141
Cdd:pfam15921 108 LRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEdsntqieqlrkmmlshegVL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 142 QE-ESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGD------QVKP--DQYTEALAQRDKRIEELNQSla 212
Cdd:pfam15921 187 QEiRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEisylkgRIFPveDQLEALKSESQNKIELLLQQ-- 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 213 AQERLVEQLSREKQQLLHLLEEPTSMEVQPMT----EELLKQQKLNSHETTITQQSVSDSHLAEL-----------QEKI 277
Cdd:pfam15921 265 HQDRIEQLISEHEVEITGLTEKASSARSQANSiqsqLEIIQEQARNQNSMYMRQLSDLESTVSQLrselreakrmyEDKI 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 278 QQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERE-------TEELYQVIEGQNDTMAKLR------ 344
Cdd:pfam15921 345 EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKElslekeqNKRLWDRDTGNSITIDHLRrelddr 424
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 345 --EMLHQSQLGQLHSSEGTSPAQQQVALLDLQS------ALFCSQLEIQK--LQRVVRQ---KERQLADAKQCVQFVEAA 411
Cdd:pfam15921 425 nmEVQRLEALLKAMKSECQGQMERQMAAIQGKNeslekvSSLTAQLESTKemLRKVVEEltaKKMTLESSERTVSDLTAS 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 412 AHESEQQKEASWKHNQELRK----ALQQLQeELQNKSQQLRAWEAEkyneirtqeqnIQHLNHSLSHKEQLL----QEFR 483
Cdd:pfam15921 505 LQEKERAIEATNAEITKLRSrvdlKLQELQ-HLKNEGDHLRNVQTE-----------CEALKLQMAEKDKVIeilrQQIE 572
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 484 ELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALeraidEKFSALEEKeKELRQLRLAVRERDHDLERLRDVLSSNEaTM 563
Cdd:pfam15921 573 NMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLEL-----QEFKILKDK-KDAKIRELEARVSDLELEKVKLVNAGSE-RL 645
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 564 QSMESLLRAKGLEVEQLSTTCQNLQWLKEEMET---KFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPG--- 637
Cdd:pfam15921 646 RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVlkrNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDgha 725
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 638 -------QSEIAEELCQ--RLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKL 695
Cdd:pfam15921 726 mkvamgmQKQITAKRGQidALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL 792
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
69-608 |
1.25e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 57.04 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 69 QALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIqllqeESRLA 148
Cdd:pfam05483 123 QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-----EKMIL 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 149 KNEAARMAAlveaeKECNLELSEKLKgvtknwEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLS---REK 225
Cdd:pfam05483 198 AFEELRVQA-----ENARLEMHFKLK------EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTfllEES 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 226 QQLLHLLEEPTSMEVQPMTEELLKQQKLNshettitqqsvsdSHLAELQEKIQQTEATNKILQEKLN-------EMSYEL 298
Cdd:pfam05483 267 RDKANQLEEKTKLQDENLKELIEKKDHLT-------------KELEDIKMSLQRSMSTQKALEEDLQiatkticQLTEEK 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 299 KCAQESSQKQDGT----IQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLhqsqlgQLHSSEgtspaqqqvaLLDLQ 374
Cdd:pfam05483 334 EAQMEELNKAKAAhsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMEL------QKKSSE----------LEEMT 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 375 SALFCSQLEIQKLQRVVRQKERQLADAKQcvqfVEAAAHESEQQKeaswkhnQELRKALQQLQEELQNKSQQLRA----- 449
Cdd:pfam05483 398 KFKNNKEVELEELKKILAEDEKLLDEKKQ----FEKIAEELKGKE-------QELIFLLQAREKEIHDLEIQLTAiktse 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 450 -WEAEKYNEIRTQEQNIQHLNHSL-SHKEQLLQEFRELLQyrDNSDKTLEanemlLEKLRQRIHDKAVALERAIdEKFSA 527
Cdd:pfam05483 467 eHYLKEVEDLKTELEKEKLKNIELtAHCDKLLLENKELTQ--EASDMTLE-----LKKHQEDIINCKKQEERML-KQIEN 538
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 528 LEEKEKELRQLRLAVRER-DHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQE 606
Cdd:pfam05483 539 LEEKEMNLRDELESVREEfIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENK 618
|
..
gi 2056392186 607 SI 608
Cdd:pfam05483 619 AL 620
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
62-513 |
2.92e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.93 E-value: 2.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 62 KPPQVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR-QFEERQQETEHVYELLENKIQL 140
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 141 LQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVkpdqytEALAQRDKRIEELNQSLAAQERLVEQ 220
Cdd:COG4717 144 LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE------EELQDLAEELEELQQRLAELEEELEE 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 221 LSREKQQLLHLLEE-PTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKI---------------QQTEATN 284
Cdd:COG4717 218 AQEELEELEEELEQlENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlgllallfLLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 285 KILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPA 364
Cdd:COG4717 298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 365 QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEAswkhnQELRKALQQLQEELQNKS 444
Cdd:COG4717 378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEEL-----EELEEELEELEEELEELR 452
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392186 445 QQLRAWEAekynEIRTQEQniqhlNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDK 513
Cdd:COG4717 453 EELAELEA----ELEQLEE-----DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
87-588 |
3.52e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 3.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 87 LKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECN 166
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 167 L-ELSEKLKGVTKNWEDVpgdqvkPDQYtEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTE 245
Cdd:COG4717 127 LlPLYQELEALEAELAEL------PERL-EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 246 ELLKQQKLnshettitqqsvsdshLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKET----LKS 321
Cdd:COG4717 200 ELEELQQR----------------LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAallaLLG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 322 RERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSS-EGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVrQKERQLAD 400
Cdd:COG4717 264 LGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLgKEAEELQALPALEELEEEELEELLAALGLPPDL-SPEELLEL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 401 AKQCVQFVEAAAHESEQQKEASWKHNQELRKALqqLQEELQNKSQQLRAWeAEKYNEIRTQEQNIQHLnhslshKEQLLQ 480
Cdd:COG4717 343 LDRIEELQELLREAEELEEELQLEELEQEIAAL--LAEAGVEDEEELRAA-LEQAEEYQELKEELEEL------EEQLEE 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 481 EFRELLQYRDNSDKtleanemllEKLRQRIHDKAVALErAIDEKFSALEEKEKELRQlRLAVRERDHDLERLRDVLSSNE 560
Cdd:COG4717 414 LLGELEELLEALDE---------EELEEELEELEEELE-ELEEELEELREELAELEA-ELEQLEEDGELAELLQELEELK 482
|
490 500
....*....|....*....|....*...
gi 2056392186 561 ATMQSMESLLRAKGLEVEQLSTTCQNLQ 588
Cdd:COG4717 483 AELRELAEEWAALKLALELLEEAREEYR 510
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
319-820 |
6.55e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.77 E-value: 6.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 319 LKSRERETEELYQVIEGQND-----TMAKLREMLHQS---QLGQLHSSEGTSPAQQQVALLDLQSAL---FCSQLEIQKL 387
Cdd:COG4717 14 FRDRTIEFSPGLNVIYGPNEagkstLLAFIRAMLLERlekEADELFKPQGRKPELNLKELKELEEELkeaEEKEEEYAEL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 388 QRVVRQKERQLADAKQcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEaEKYNEIRTQEQNIQH 467
Cdd:COG4717 94 QEELEELEEELEELEA-----ELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELE-ERLEELRELEEELEE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 468 LNHSLSHKEQLLQEfrellQYRDNSDKTLEANEMLLEKLrQRIHDKAVALERAIDEKFSALEEKEKELRQLRlAVRERDH 547
Cdd:COG4717 168 LEAELAELQEELEE-----LLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEELEELEEELEQLE-NELEAAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 548 DLERLRDVLSSNEATmqSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEvEDLS 627
Cdd:COG4717 241 LEERLKEARLLLLIA--AALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL-EELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 628 ATLLCKL-------GPGQSEIAEELCQRLQRKERMLQDLLSDRNK-QVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL 699
Cdd:COG4717 318 EEELEELlaalglpPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAEAGVEDEEELRAALEQAEEY 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 700 MERNSELQALRQYLGgrdslmSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTS--LTAKEDVSIPRSTLGDLDTV 777
Cdd:COG4717 398 QELKEELEELEEQLE------ELLGELEELLEALDEEELEEELEELEEELEELEEELEelREELAELEAELEQLEEDGEL 471
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 2056392186 778 AGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQ 820
Cdd:COG4717 472 AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
270-484 |
1.03e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 270 LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLhQ 349
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL-A 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 350 SQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLeIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQEL 429
Cdd:COG4942 108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392186 430 RKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRE 484
Cdd:COG4942 187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1066 |
1.18e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 309 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLRE-----MLHQSQLGQLHSSEGTSPAQQQVALLDLQSALfcsQLE 383
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaERYQALLKEKREYEGYELLKEKEALERQKEAI---ERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 384 IQKLQRVVRQKERQLAD-AKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQE 462
Cdd:TIGR02169 246 LASLEEELEKLTEEISElEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 463 QNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEK--------- 533
Cdd:TIGR02169 326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkreinelk 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 534 -ELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSttcQNLQWLKEEMETKFSRWQKEQESiIQQL 612
Cdd:TIGR02169 406 rELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELYDLKEE-YDRV 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 613 QTSLHDRNKEVEDLSATL--LCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTreqESQA 690
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQAraSEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVV---EDDA 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 691 AAEKLVQALMERNselqalrqylGGRdslMSQAPISNQQAEVTPTGRLGKQTDQG-SMQIPSRDD-----------STSL 758
Cdd:TIGR02169 559 VAKEAIELLKRRK----------AGR---ATFLPLNKMRDERRDLSILSEDGVIGfAVDLVEFDPkyepafkyvfgDTLV 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 759 TakEDVSIPRSTLGDLDTVAgLEKEL----------SNAKEELELMAKKERESQMELSA-LQSMmavqEEELQVQAADME 827
Cdd:TIGR02169 626 V--EDIEAARRLMGKYRMVT-LEGELfeksgamtggSRAPRGGILFSRSEPAELQRLRErLEGL----KRELSSLQSELR 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 828 SLTRNIQIKEDLIKDLQMQLVDPEDipAMERLTQEVLLLREKVASVESQGQEISgNRRQQLLLMLEGLVDERSRLNEALQ 907
Cdd:TIGR02169 699 RIENRLDELSQELSDASRKIGEIEK--EIEQLEQEEEKLKERLEELEEDLSSLE-QEIENVKSELKELEARIEELEEDLH 775
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 908 AERQlysSLVKFHAHPeSSERDRTLQVELEGAQVLRSRLEEVLgRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIE 987
Cdd:TIGR02169 776 KLEE---ALNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392186 988 EEAAHHSHQQLVKVALEKSLATVETQnpsfsppspmggdsNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEA 1066
Cdd:TIGR02169 851 SIEKEIENLNGKKEELEEELEELEAA--------------LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
75-608 |
1.26e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.91 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 75 EKNIELKVEVESLKRElqdKKQHLDKTWADVENLNSqNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 154
Cdd:PRK03918 182 EKFIKRTENIEELIKE---KEKELEEVLREINEISS-ELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 155 MAALVEAEKECNlELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSlaaqERLVEQLSREKQQLLHLLEE 234
Cdd:PRK03918 258 EEKIRELEERIE-ELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREI----EKRLSRLEEEINGIEERIKE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 235 PTSMEVQpmTEELLKQQKLNSHETTITQQSVSDSHLA-ELQEKIQQTEATNKILQ-EKLNEMSYELKCAQESSQKQDGTI 312
Cdd:PRK03918 333 LEEKEER--LEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEISKI 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 313 QNLKETLKSRERETEELYQVIEGQNDTMAKLREML---HQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKlqr 389
Cdd:PRK03918 411 TARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteeHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK--- 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 390 vVRQKERQLADAKQCVQFVEAAAHESE----QQKEASWKHNQELRKALQQLQEELQN------KSQQLRAWEAEKYNEIR 459
Cdd:PRK03918 488 -VLKKESELIKLKELAEQLKELEEKLKkynlEELEKKAEEYEKLKEKLIKLKGEIKSlkkeleKLEELKKKLAELEKKLD 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 460 TQEQNIQHLNHSLSHK-----EQLLQEFRELLQYRD------NSDKTLEANEMLLEKLRqrihDKAVALERAIDEKFSAL 528
Cdd:PRK03918 567 ELEEELAELLKELEELgfesvEELEERLKELEPFYNeylelkDAEKELEREEKELKKLE----EELDKAFEELAETEKRL 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 529 EEKEKELRQLRLAVRERDHdlERLRDVLSSNEATMQSMESllRAKGLEvEQLSTTCQNLQWLKEEMEtKFSRWQKEQESI 608
Cdd:PRK03918 643 EELRKELEELEKKYSEEEY--EELREEYLELSRELAGLRA--ELEELE-KRREEIKKTLEKLKEELE-EREKAKKELEKL 716
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
53-858 |
1.96e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.51 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 53 QTYSLRAFEKPPQVQTQALRDFEKNIElkvEVESLKRELQDKKQHLDKTWADVENLNSQ----------------NEAEL 116
Cdd:TIGR00606 232 QLESSREIVKSYENELDPLKNRLKEIE---HNLSKIMKLDNEIKALKSRKKQMEKDNSElelkmekvfqgtdeqlNDLYH 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 117 RRQFEERQQETEHV-----YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE-----LSEKLKGVTKNWEDVPGD 186
Cdd:TIGR00606 309 NHQRTVREKERELVdcqreLEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRArdsliQSLATRLELDGFERGPFS 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 187 QVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVS 266
Cdd:TIGR00606 389 ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEG 468
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 267 DS-HLAELQEKIQQTEATNKILQEKLNE--MSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKL 343
Cdd:TIGR00606 469 SSdRILELDQELRKAERELSKAEKNSLTetLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 344 REMLHQSQLG--QLHSSEGTSPAQQQValldlqsalfcsQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAH------ES 415
Cdd:TIGR00606 549 EQIRKIKSRHsdELTSLLGYFPNKKQL------------EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNhinnelES 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 416 EQQKEASWKHN-------QELRKALQQLQEELQNKSQQLRAWEAEK------YNEIRTQEQNIQHLNHSLSHKEQLLQEF 482
Cdd:TIGR00606 617 KEEQLSSYEDKlfdvcgsQDEESDLERLKEEIEKSSKQRAMLAGATavysqfITQLTDENQSCCPVCQRVFQTEAELQEF 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 483 RELLQYRDNSDKT-LEANEMLLEKLRQRIHDKAVALERaideKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEA 561
Cdd:TIGR00606 697 ISDLQSKLRLAPDkLKSTESELKKKEKRRDEMLGLAPG----RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET 772
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 562 TMQS-MESLLRAKGLEVEqlSTTCQNLQWLKEEMETKFSRWQKEQESIiqQLQTSLHDRNKEVEDlsatllcklgpgqse 640
Cdd:TIGR00606 773 LLGTiMPEEESAKVCLTD--VTIMERFQMELKDVERKIAQQAAKLQGS--DLDRTVQQVNQEKQE--------------- 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 641 iAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQ---SVSTREQESQAAAEKLVqalmERNSELQALRQylggrd 717
Cdd:TIGR00606 834 -KQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSeklQIGTNLQRRQQFEEQLV----ELSTEVQSLIR------ 902
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 718 slmsqaPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRStlgDLDTVAGLEKELSNAKEELELMAKK 797
Cdd:TIGR00606 903 ------EIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKE---KVKNIHGYMKDIENKIQDGKDDYLK 973
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2056392186 798 ERESqmELSALQSMMAVQEEELQVQAADMESLTRNI---QIKEDLIKDLQMQLVDPEDIPAMER 858
Cdd:TIGR00606 974 QKET--ELNTVNAQLEECEKHQEKINEDMRLMRQDIdtqKIQERWLQDNLTLRKRENELKEVEE 1035
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
286-723 |
3.33e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 286 ILQEKLNEMSYEL-KCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREmlhqsqlgqlhssegtspA 364
Cdd:COG4717 46 MLLERLEKEADELfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEE------------------L 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 365 QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKS 444
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLS 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 445 QQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEK 524
Cdd:COG4717 188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 525 FSALEEKEKELRQLRLAVRErdHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLqWLKEEMETKFSRWQKE 604
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLA--LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL-GLPPDLSPEELLELLD 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 605 QESIIQQLQTSLHDRNKEV-----EDLSATLLCKLGPGQSEIAEELCQRLQRKERmLQDLLSDRNKQVLEHEMEIQGLLQ 679
Cdd:COG4717 345 RIEELQELLREAEELEEELqleelEQEIAALLAEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLE 423
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2056392186 680 SVSTREQESQaaAEKLVQALMERNSELQALRQYLGGRDSLMSQA 723
Cdd:COG4717 424 ALDEEELEEE--LEELEEELEELEEELEELREELAELEAELEQL 465
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1808-1985 |
3.63e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.63 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1808 ADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH 1887
Cdd:COG1196 241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1888 VSREHSQET---ESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQ 1964
Cdd:COG1196 321 LEEELAELEeelEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
170 180
....*....|....*....|.
gi 2056392186 1965 QCEEKQQLFESLQSELQIYEA 1985
Cdd:COG1196 401 QLEELEEAEEALLERLERLEE 421
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
81-611 |
3.76e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 52.42 E-value: 3.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 81 KVEVESLKrELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEesrlaKNEAARMAALVE 160
Cdd:pfam05483 278 KLQDENLK-ELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEE-----LNKAKAAHSFVV 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 161 AEKECNLELSEKLKGVTKNWEDVPGDQVKpdQYTEALAQRDKRIEELNQSLAAQERLVEQLSR---EKQQLLHLLE--EP 235
Cdd:pfam05483 352 TEFEATTCSLEELLRTEQQRLEKNEDQLK--IITMELQKKSSELEEMTKFKNNKEVELEELKKilaEDEKLLDEKKqfEK 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 236 TSMEVQPMTEELL-----KQQKLNSHETTITQQSVSDSH----LAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQ 306
Cdd:pfam05483 430 IAEELKGKEQELIfllqaREKEIHDLEIQLTAIKTSEEHylkeVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAS 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 307 KQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTspaqqqvalldlqsalfcsQLEIQK 386
Cdd:pfam05483 510 DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEV-------------------KCKLDK 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 387 LQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEkyneirtqeqnIQ 466
Cdd:pfam05483 571 SEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIK-----------VN 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 467 HLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEK-------FSALEEKEKElrQLR 539
Cdd:pfam05483 640 KLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRcqhkiaeMVALMEKHKH--QYD 717
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392186 540 LAVRERDHDLERLRDVLSSNEATMQSMESLLraKGLEVEQLSTTCQnLQWLKEEMEtKFSRWQKEQESIIQQ 611
Cdd:pfam05483 718 KIIEERDSELGLYKNKEQEQSSAKAALEIEL--SNIKAELLSLKKQ-LEIEKEEKE-KLKMEAKENTAILKD 785
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
252-722 |
4.01e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 252 KLNSHETTITQqsvSDSHLAELQEKIQQTEATNKILQEKLNEmsYELKcaQESSQKQDGTIQNLKETLKSRERETEELYQ 331
Cdd:PRK02224 207 RLNGLESELAE---LDEEIERYEEQREQARETRDEADEVLEE--HEER--REELETLEAEIEDLRETIAETEREREELAE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 332 VIEGQNDTMAKLREMLHqsqlGQLHSSEGTSPAQQqvALLDLQSALfcsQLEIQKLQRVVRQKERQLADAKQCVQFVEAA 411
Cdd:PRK02224 280 EVRDLRERLEELEEERD----DLLAEAGLDDADAE--AVEARREEL---EDRDEELRDRLEECRVAAQAHNEEAESLRED 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 412 AHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAE------KYNEIRTQEQNIQHLNHSL-SHKEQLLQEFRE 484
Cdd:PRK02224 351 ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEieelreRFGDAPVDLGNAEDFLEELrEERDELREREAE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 485 LLQYRDNSDKTLEANEMLLEKLR-----QRIHDKAVAleRAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDV---- 555
Cdd:PRK02224 431 LEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveae 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 556 --LSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQK---EQESIIQQLQTSLHDRNKEVEDLSATL 630
Cdd:PRK02224 509 drIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREaaaEAEEEAEEAREEVAELNSKLAELKERI 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 631 --LCKLGPGQSEIAE--ELCQRLQRKERMLQDL-------LSDRNKQVLEHEMEIQGllqsvsTREQESQAAAEKLVQAL 699
Cdd:PRK02224 589 esLERIRTLLAAIADaeDEIERLREKREALAELnderrerLAEKRERKRELEAEFDE------ARIEEAREDKERAEEYL 662
|
490 500
....*....|....*....|...
gi 2056392186 700 MERNSELQALRQylgGRDSLMSQ 722
Cdd:PRK02224 663 EQVEEKLDELRE---ERDDLQAE 682
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
198-576 |
5.25e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 51.88 E-value: 5.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 198 AQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEE---------PTSMEVQPMTEELLKQQKLNSHETtitqqsvsds 268
Cdd:PRK04863 782 AAREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAfsrfigshlAVAFEADPEAELRQLNRRRVELER---------- 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 269 HLAELQEKIQQTEATNKILQEKLNEMSyelKCAQESSQKQDgtiqnlkETLKSRERETEElyQVIEGQNdtmAKLREMLH 348
Cdd:PRK04863 852 ALADHESQEQQQRSQLEQAKEGLSALN---RLLPRLNLLAD-------ETLADRVEEIRE--QLDEAEE---AKRFVQQH 916
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 349 QSQLGQLhssegtspaQQQVALLDlqsalfCSQLEIQKLQRVVRQKERQLADAKQCV----QFVEAAAH----ESEQQKE 420
Cdd:PRK04863 917 GNALAQL---------EPIVSVLQ------SDPEQFEQLKQDYQQAQQTQRDAKQQAfaltEVVQRRAHfsyeDAAEMLA 981
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 421 ASWKHNQELRKALQQLQEELQNKSQQLRAWEAE--KYNEIRTQeqniqhLNHSLSHKEQLLQEFRELLQyrdnsDKTLEA 498
Cdd:PRK04863 982 KNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQlaQYNQVLAS------LKSSYDAKRQMLQELKQELQ-----DLGVPA 1050
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 499 NEMLLEKLRQRiHDKAVALERAIDEKFSALEEK----EKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKG 574
Cdd:PRK04863 1051 DSGAEERARAR-RDELHARLSANRSRRNQLEKQltfcEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNG 1129
|
..
gi 2056392186 575 LE 576
Cdd:PRK04863 1130 VE 1131
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
387-878 |
7.39e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 7.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 387 LQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRaweaEKYNEIRTQEQNIQ 466
Cdd:pfam05557 11 LSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALR----EQAELNRLKKKYLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 467 HLNHSLSHKEQLL-----------QEFRELLQYRDNSDKTLEANEMLLEKLRQRiHDKAVALERAIDEKFSALEEKEKEL 535
Cdd:pfam05557 87 ALNKKLNEKESQLadarevisclkNELSELRRQIQRAELELQSTNSELEELQER-LDLLKAKASEAEQLRQNLEKQQSSL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 536 RQLRLAVRERDHDLERLRD----VLSSNE--ATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEE---METKFSRWQKEQE 606
Cdd:pfam05557 166 AEAEQRIKELEFEIQSQEQdseiVKNSKSelARIPELEKELERLREHNKHLNENIENKLLLKEEvedLKRKLEREEKYRE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 607 SII------QQLQTSLHDRNKEVEDLSATLlcklgPGQSEIAEELCQrLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQS 680
Cdd:pfam05557 246 EAAtlelekEKLEQELQSWVKLAQDTGLNL-----RSPEDLSRRIEQ-LQQREIVLKEENSSLTSSARQLEKARRELEQE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 681 VS----------TREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQ---------------------- 728
Cdd:pfam05557 320 LAqylkkiedlnKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQllerieeaedmtqkmqahneem 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 729 -----QAEVTPTG-RLGKQTDQGSMQIPSRDDST--SLTAKEDVSIPRStlgDLDTVAGLEKELSNAKEELEL-MAKKER 799
Cdd:pfam05557 400 eaqlsVAEEELGGyKQQAQTLERELQALRQQESLadPSYSKEEVDSLRR---KLETLELERQRLREQKNELEMeLERRCL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 800 ESQMELS---ALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIP--AMERLTQEVLLLREKVASVE 874
Cdd:pfam05557 477 QGDYDPKktkVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPetTSTMNFKEVLDLRKELESAE 556
|
....
gi 2056392186 875 SQGQ 878
Cdd:pfam05557 557 LKNQ 560
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
92-651 |
1.13e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.94 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 92 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLaKNEAARMAALVEAEKECNLELSE 171
Cdd:pfam01576 18 KERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQEL-EEILHELESRLEEEEERSQQLQN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 172 KLKGVTKNWEDVPgDQVKPDQYTEALAQRDK-----RIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMevqpMTEE 246
Cdd:pfam01576 97 EKKKMQQHIQDLE-EQLDEEEAARQKLQLEKvtteaKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSN----LAEE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 247 LLKQQKL----NSHETTITqqsvsdshlaELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSR 322
Cdd:pfam01576 172 EEKAKSLsklkNKHEAMIS----------DLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 323 ERETEELYQVIEGQ----NDTMAKLREML-HQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKL-------QRV 390
Cdd:pfam01576 242 EEELQAALARLEEEtaqkNNALKKIRELEaQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTldttaaqQEL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 391 VRQKERQLADAKQCVQfVEAAAHESeQQKEASWKHNQELRKALQQLQEELQNKS------QQLRAWEAEKYNEIRTQEQN 464
Cdd:pfam01576 322 RSKREQEVTELKKALE-EETRSHEA-QLQEMRQKHTQALEELTEQLEQAKRNKAnlekakQALESENAELQAELRTLQQA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 465 IQHLNHSLSHKEQLLQEfrelLQYRDNSDktleanemllEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRE 544
Cdd:pfam01576 400 KQDSEHKRKKLEGQLQE----LQARLSES----------ERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSS 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 545 RDHDLERLRDVLSsnEATMQSMESLLRAKGLEVEQLSTTCQnlqwLKEEMETKfsrwqKEQESIIQQLQTSLHDRNKEVE 624
Cdd:pfam01576 466 LESQLQDTQELLQ--EETRQKLNLSTRLRQLEDERNSLQEQ----LEEEEEAK-----RNVERQLSTLQAQLSDMKKKLE 534
|
570 580
....*....|....*....|....*..
gi 2056392186 625 DLSATLlcklgpgqsEIAEELCQRLQR 651
Cdd:pfam01576 535 EDAGTL---------EALEEGKKRLQR 552
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
61-711 |
1.14e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 61 EKPPQVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQL 140
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 141 LQ--EESRLA----KNEAARMAALV-EAEKECNLELSEKLKGVTKNWEDVPGDQVKPdqytealAQRDKRIEELNQSLAA 213
Cdd:PTZ00121 1163 ARkaEEARKAedakKAEAARKAEEVrKAEELRKAEDARKAEAARKAEEERKAEEARK-------AEDAKKAEAVKKAEEA 1235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 214 QERLVEQLSREKQQllhLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQsVSDSHLAELQEKIQQTEATNKIlqEKLNE 293
Cdd:PTZ00121 1236 KKDAEEAKKAEEER---NNEEIRKFEEARMAHFARRQAAIKAEEARKADE-LKKAEEKKKADEAKKAEEKKKA--DEAKK 1309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 294 MSYELKCAQESSQKQdgtiQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDL 373
Cdd:PTZ00121 1310 KAEEAKKADEAKKKA----EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 374 QSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASW--KHNQELRKAlqqlqEELQNKSQQLR-AW 450
Cdd:PTZ00121 1386 KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEakKKAEEAKKA-----DEAKKKAEEAKkAE 1460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 451 EAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAiDEKFSALEE 530
Cdd:PTZ00121 1461 EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA-EEAKKADEA 1539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 531 KEKELRQLRLAVR--ERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESI 608
Cdd:PTZ00121 1540 KKAEEKKKADELKkaEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 609 IQQLQTslhdRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQ----RKERMLQDLLSDRNK-QVLEHEMEIQGLLQSVST 683
Cdd:PTZ00121 1620 IKAEEL----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEenkiKAAEEAKKAEEDKKKaEEAKKAEEDEKKAAEALK 1695
|
650 660
....*....|....*....|....*...
gi 2056392186 684 REQESQAAAEKLVQALMERNSELQALRQ 711
Cdd:PTZ00121 1696 KEAEEAKKAEELKKKEAEEKKKAEELKK 1723
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
360-567 |
1.81e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 360 GTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEE 439
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 440 LQNKSQQLRAWEAEKYNEIRTQEQNIQH-------LNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQrihd 512
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA---- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2056392186 513 kavALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSME 567
Cdd:COG4942 168 ---ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
194-556 |
3.15e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 3.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 194 TEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLlhlleeptsmevqpmTEELLKQQKLNSHETTITQQSVSDSHLAEL 273
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDAL---------------QERREALQRLAEYSWDEIDVASAEREIAEL 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 274 QEKIQQTEATNKILQEkLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLG 353
Cdd:COG4913 674 EAELERLDASSDDLAA-LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 354 QLHSSEGTSPAQQQVAlLDLQSalfcsqlEIQKLQRVVRQKERQLADAKQcvQFVEAAAHESeQQKEASWKHNQELRKAL 433
Cdd:COG4913 753 ERFAAALGDAVERELR-ENLEE-------RIDALRARLNRAEEELERAMR--AFNREWPAET-ADLDADLESLPEYLALL 821
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 434 QQLQEE------------LQNKSQQLRAWEAEK-YNEIRTQEQNIQHLNHSLSHkeqllqefrelLQYRDNSDKTLEANE 500
Cdd:COG4913 822 DRLEEDglpeyeerfkelLNENSIEFVADLLSKlRRAIREIKERIDPLNDSLKR-----------IPFGPGRYLRLEARP 890
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2056392186 501 MLLE---KLRQRIHDkavALERAIDEKFSALEEKEKELRQL--RLAVRERDHDLERLRDVL 556
Cdd:COG4913 891 RPDPevrEFRQELRA---VTSGASLFDEELSEARFAALKRLieRLRSEEEESDRRWRARVL 948
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
380-556 |
3.42e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 380 SQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEEL-QNKSQQLRAWEAekynEI 458
Cdd:COG4913 272 AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrGNGGDRLEQLER----EI 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 459 RTQEQNIQHLNHSLSHKEQLLQEF--------RELLQYRDNSDKTLEAnemlLEKLRQRIHDKAVALERAIDEKFSALEE 530
Cdd:COG4913 348 ERLERELEERERRRARLEALLAALglplpasaEEFAALRAEAAALLEA----LEEELEALEEALAEAEAALRDLRRELRE 423
|
170 180
....*....|....*....|....*.
gi 2056392186 531 KEKELRQLRLAVRERDHDLERLRDVL 556
Cdd:COG4913 424 LEAEIASLERRKSNIPARLLALRDAL 449
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
79-291 |
4.51e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 79 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQneaelRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAAL 158
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 159 VEAEKEcnlELSEKLKGVTKNWE----------DVPGDQVKPDQYTEALAQ-RDKRIEELNQSLAAQERLVEQLSREKQQ 227
Cdd:COG4942 99 LEAQKE---ELAELLRALYRLGRqpplalllspEDFLDAVRRLQYLKYLAPaRREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2056392186 228 LLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSdshLAELQEKIQQTEATNKILQEKL 291
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAE---LAELQQEAEELEALIARLEAEA 236
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
192-711 |
4.67e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.81 E-value: 4.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 192 QYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLA 271
Cdd:TIGR00618 153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLR 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 272 ELQEKIQQTEATNKILQEKLNEmsyelkcaQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDtmaKLREMLHQSQ 351
Cdd:TIGR00618 233 EALQQTQQSHAYLTQKREAQEE--------QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARK---AAPLAAHIKA 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 352 LGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFveAAAHESEQQKEASWKHNQELRK 431
Cdd:TIGR00618 302 VTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHI--RDAHEVATSIREISCQQHTLTQ 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 432 ALQQLQEELQNKSQQLRAWEAEKYN--------EIRTQEQNIQHLNHSLSHKEQLLQEFRELLQ--YRDNSDKTLEANEM 501
Cdd:TIGR00618 380 HIHTLQQQKTTLTQKLQSLCKELDIlqreqatiDTRTSAFRDLQGQLAHAKKQQELQQRYAELCaaAITCTAQCEKLEKI 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 502 LLEKLRQRIHDKAVALERAidekfSALEEKEKELRQLRLAVRERDHDLER-LRDVLSSNEATMQSM------ESLLRAKG 574
Cdd:TIGR00618 460 HLQESAQSLKEREQQLQTK-----EQIHLQETRKKAVVLARLLELQEEPCpLCGSCIHPNPARQDIdnpgplTRRMQRGE 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 575 LEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATL-----LCKLGPGQSEIAEELCQRL 649
Cdd:TIGR00618 535 QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQnitvrLQDLTEKLSEAEDMLACEQ 614
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392186 650 QRKERMLQDLLSDRNK-QVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQ 711
Cdd:TIGR00618 615 HALLRKLQPEQDLQDVrLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLAS 677
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
364-576 |
4.75e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 4.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 364 AQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNK 443
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 444 SQQLRAWEAEKY--------------NEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQR 509
Cdd:COG4942 103 KEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 510 IHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLE 576
Cdd:COG4942 183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
70-329 |
6.13e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.53 E-value: 6.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 70 ALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA------ELRRQFEERQQETEHVYELLEN---KIQL 140
Cdd:TIGR02169 669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDasrkigEIEKEIEQLEQEEEKLKERLEEleeDLSS 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 141 LQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTK--NWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLV 218
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 219 EQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVS----DSHLAELQEKIQQTEATNKILQEKLNEM 294
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAlrdlESRLGDLKKERDELEAQLRELERKIEEL 908
|
250 260 270
....*....|....*....|....*....|....*
gi 2056392186 295 SYELKCAQESSQKQDGTIQNLKETLKSRERETEEL 329
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
475-729 |
6.49e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 6.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 475 KEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIhdkaVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRD 554
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 555 VLSSNEATMQSMESLLRAK-GLEVEQLSTTCQNLQWLKEemetkFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLlck 633
Cdd:COG4942 105 ELAELLRALYRLGRQPPLAlLLSPEDFLDAVRRLQYLKY-----LAPARREQAEELRADLAELAALRAELEAERAEL--- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 634 lgpgqseiaEELCQRLQRKERMLQDLLSDRNKqvlehemeiqgLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYL 713
Cdd:COG4942 177 ---------EALLAELEEERAALEALKAERQK-----------LLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
250
....*....|....*.
gi 2056392186 714 GGRDSLMSQAPISNQQ 729
Cdd:COG4942 237 AAAAERTPAAGFAALK 252
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
83-695 |
1.08e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.64 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 83 EVESLKRELQDKKQHLD-------------------KTWADVENLNSQNEAELRRQFEERQQE-TEHVYELlenkiqllq 142
Cdd:COG3096 390 EVDSLKSQLADYQQALDvqqtraiqyqqavqalekaRALCGLPDLTPENAEDYLAAFRAKEQQaTEEVLEL--------- 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 143 eESRLAKNEAARmaalveAEKECNLELSEKLKG-VTKNWEDVPGDQV---KPDQytEALAQRDKRIE----ELNQSLAAQ 214
Cdd:COG3096 461 -EQKLSVADAAR------RQFEKAYELVCKIAGeVERSQAWQTARELlrrYRSQ--QALAQRLQQLRaqlaELEQRLRQQ 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 215 ERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKI---LQEKL 291
Cdd:COG3096 532 QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAwlaAQDAL 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 292 NEMSYELKCAQESSQKQDGTIQNLKEtlksRERETEELYQVIEGQNDTMAKLREMLHQ------SQLGQLHSSEG---TS 362
Cdd:COG3096 612 ERLREQSGEALADSQEVTAAMQQLLE----REREATVERDELAARKQALESQIERLSQpggaedPRLLALAERLGgvlLS 687
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 363 PAQQQVALLDLQ--SALFC---SQLEIQKLQRVVRQKErQLADAKQCVQFVE-------AAAHESEQQKEASWKHNQEL- 429
Cdd:COG3096 688 EIYDDVTLEDAPyfSALYGparHAIVVPDLSAVKEQLA-GLEDCPEDLYLIEgdpdsfdDSVFDAEELEDAVVVKLSDRq 766
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 430 -------------RKALQQLQEELQNKSQQLraweAEKYNEIRTQEQNIQHLNHSLShkeQLLQEFRELlqyrdnsdkTL 496
Cdd:COG3096 767 wrysrfpevplfgRAAREKRLEELRAERDEL----AEQYAKASFDVQKLQRLHQAFS---QFVGGHLAV---------AF 830
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 497 EAN-EMLLEKLRQRIhdkavaleRAIDEKFSALEEKEKELRQLRLAVRER---------------DHDLERLRDVLSSNE 560
Cdd:COG3096 831 APDpEAELAALRQRR--------SELERELAQHRAQEQQLRQQLDQLKEQlqllnkllpqanllaDETLADRLEELREEL 902
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 561 ATMQSMESLLRAKGLEVEQLSTTCQNLQ---WLKEEMETKFSRWQKEQESIIQQL-------QTSLH-------DRNKEV 623
Cdd:COG3096 903 DAAQEAQAFIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIfalsevvQRRPHfsyedavGLLGEN 982
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392186 624 EDLSATLLCKLgpgqsEIAEELCQRLQRKERMLQDLLSDRNkQVLehemeiQGLLQSVSTREQESQAAAEKL 695
Cdd:COG3096 983 SDLNEKLRARL-----EQAEEARREAREQLRQAQAQYSQYN-QVL------ASLKSSRDAKQQTLQELEQEL 1042
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
71-713 |
1.09e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 71 LRDFEKNIE-LKVEVESLKRELQDKKQHLDKTWADVENLnsqnEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 149
Cdd:TIGR02169 338 IEELEREIEeERKRRDKLTEEYAELKEELEDLRAELEEV----DKEFAETRDELKDYREKLEKLKREINELKRELDRLQE 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 150 NEAARMAALVEAEkecnlelseklkgvtknwEDVPGDQVKPDQYTEALAQRDKRIEELNQSLaaqERLVEQLSREKQQLL 229
Cdd:TIGR02169 414 ELQRLSEELADLN------------------AAIAGIEAKINELEEEKEDKALEIKKQEWKL---EQLAADLSKYEQELY 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 230 HLLEEptsmevqpmteellkQQKLNshettitqqsvsdSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQD 309
Cdd:TIGR02169 473 DLKEE---------------YDRVE-------------KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 310 GTIQNLKETLKSRERETE-----ELYQVIEGQNDTMAKLREMLHQSQLGQL----------HSSEGTSPAQQQVA--LLD 372
Cdd:TIGR02169 525 GTVAQLGSVGERYATAIEvaagnRLNNVVVEDDAVAKEAIELLKRRKAGRAtflplnkmrdERRDLSILSEDGVIgfAVD 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 373 L---------------QSALFCSQLEIQKLQ----RVVRQKERQL---------ADAKQCVQFVEAAAHESEQQKEASWK 424
Cdd:TIGR02169 605 LvefdpkyepafkyvfGDTLVVEDIEAARRLmgkyRMVTLEGELFeksgamtggSRAPRGGILFSRSEPAELQRLRERLE 684
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 425 HNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYrdnSDKTLEANEMLLE 504
Cdd:TIGR02169 685 GLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS---LEQEIENVKSELK 761
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 505 KLRQRIHDKavalERAIDEKFSALEEKEKELRQLRlaVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTC 584
Cdd:TIGR02169 762 ELEARIEEL----EEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 585 QNLQWLKEEMETKFSRWQKEQESIiqqlqtslhdrNKEVEDLsatllcklgpgQSEIAEelcqrLQRKERMLQDLLSDRN 664
Cdd:TIGR02169 836 QELQEQRIDLKEQIKSIEKEIENL-----------NGKKEEL-----------EEELEE-----LEAALRDLESRLGDLK 888
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 2056392186 665 KQVLEHEMEIQGLLQsvstREQESQAAAEKLVQALMERNSELQALRQYL 713
Cdd:TIGR02169 889 KERDELEAQLRELER----KIEELEAQIEKKRKRLSELKAKLEALEEEL 933
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
266-454 |
1.11e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.13 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 266 SDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAK-LR 344
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 345 EMLHQ----SQLGQLHSSEGTSPAQQQVALLD-LQSAlfcSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQK 419
Cdd:COG3883 94 ALYRSggsvSYLDVLLGSESFSDFLDRLSALSkIADA---DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190
....*....|....*....|....*....|....*
gi 2056392186 420 EASWKHNQELRKALQQLQEELQNKSQQLRAWEAEK 454
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAEL 205
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
110-575 |
1.24e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 47.44 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 110 SQNEAE-LRRQFEERQQETEHVYELLENKIQLLQEEsrlAKNEAARMAALVEAEkecnlELSEKLKGVTKNWEDVPGD-- 186
Cdd:pfam07111 195 AQKEAElLRKQLSKTQEELEAQVTLVESLRKYVGEQ---VPPEVHSQTWELERQ-----ELLDTMQHLQEDRADLQATve 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 187 --QVKPDQYTEALAQRDkriEELNQSLAAQERLVEQLSREKQQLLHLLEEPT-SMEVQpmteelLKQQKLnSHETTITQQ 263
Cdd:pfam07111 267 llQVRVQSLTHMLALQE---EELTRKIQPSDSLEPEFPKKCRSLLNRWREKVfALMVQ------LKAQDL-EHRDSVKQL 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 264 SVsdsHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERET----EELYQVIEGQNDT 339
Cdd:pfam07111 337 RG---QVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTasaeEQLKFVVNAMSST 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 340 MAKLREMLHQSQ----------------LGQLHSSEGTSPAQQQVALLDLQS-----------ALFCSQLEIQKLQRVVR 392
Cdd:pfam07111 414 QIWLETTMTRVEqavaripslsnrlsyaVRKVHTIKGLMARKVALAQLRQEScpppppappvdADLSLELEQLREERNRL 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 393 QKERQLAdAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAW---------EAEKYNEIRTQEQ 463
Cdd:pfam07111 494 DAELQLS-AHLIQQEVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVArqgqqesteEAASLRQELTQQQ 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 464 NI--QHLNHSLSHKEQLLQEfrellQYRDNSDKTLEAnemlleklrQRIHDKAVALERAIDEKFSALEEKEKELRqlRLA 541
Cdd:pfam07111 573 EIygQALQEKVAEVETRLRE-----QLSDTKRRLNEA---------RREQAKAVVSLRQIQHRATQEKERNQELR--RLQ 636
|
490 500 510
....*....|....*....|....*....|....
gi 2056392186 542 VRERDHDLERLRDVLSSNEATMQSMESLLRAKGL 575
Cdd:pfam07111 637 DEARKEEGQRLARRVQELERDKNLMLATLQQEGL 670
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1811-2007 |
2.01e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.85 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1811 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLshvsr 1890
Cdd:COG1196 339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----- 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1891 ehsQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQ 1970
Cdd:COG1196 414 ---ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
170 180 190
....*....|....*....|....*....|....*..
gi 2056392186 1971 QLFESLQSELQIYEALYGNSKKGLKDSAVSPPVRDVG 2007
Cdd:COG1196 491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
287-847 |
2.07e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.65 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 287 LQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQ 366
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 367 QVALLDlQSALFCSQLEIQKLQRVVRQKERQLADAKQC-VQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNK-- 443
Cdd:pfam15921 156 AAKCLK-EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIlVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEis 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 444 ---------SQQLRAWEAEKYNEI--------------------------------RTQEQNIQ---------------- 466
Cdd:pfam15921 235 ylkgrifpvEDQLEALKSESQNKIelllqqhqdrieqliseheveitgltekassaRSQANSIQsqleiiqeqarnqnsm 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 467 ---HLNHSLSHKEQLLQEFRELLQYRDNSDKTLE-----ANEMLLEKLRQR--IHDKAVALERAIDEKFSALEEKEKELR 536
Cdd:pfam15921 315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERdqFSQESGNLDDQLQKLLADLHKREKELS 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 537 QlrlavrERDHDlERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQW-LKEEMETKFSRWQKEQE------SII 609
Cdd:pfam15921 395 L------EKEQN-KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSeCQGQMERQMAAIQGKNEslekvsSLT 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 610 QQLQTSLHDRNKEVEDLSATllcKLGPGQSE-IAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGL--LQSVSTREQ 686
Cdd:pfam15921 468 AQLESTKEMLRKVVEELTAK---KMTLESSErTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELqhLKNEGDHLR 544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 687 ESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTpTGRLGKQTDQGSMQIpsrDDSTSLTAKEDVSI 766
Cdd:pfam15921 545 NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE-KAQLEKEINDRRLEL---QEFKILKDKKDAKI 620
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 767 P--RSTLGDLDtvagLEK-ELSNAKEElelMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIK----EDL 839
Cdd:pfam15921 621 RelEARVSDLE----LEKvKLVNAGSE---RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKseemETT 693
|
....*...
gi 2056392186 840 IKDLQMQL 847
Cdd:pfam15921 694 TNKLKMQL 701
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
65-731 |
2.10e-04 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 46.72 E-value: 2.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 65 QVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQEteHVYELLENKIQLLQEE 144
Cdd:PRK10246 240 QQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRPHWERIQE--QSAALAHTRQQIEEVN 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 145 SRLAKNEAARMAALVEAEKECNLELSEKlkGVTKNWedvpgdqvkpdqyteaLAQRDkRIEELNQSLAAQERLVEQLSRE 224
Cdd:PRK10246 318 TRLQSTMALRARIRHHAAKQSAELQAQQ--QSLNTW----------------LAEHD-RFRQWNNELAGWRAQFSQQTSD 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 225 KQQLLHLLEEPTSMEVQ----PMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQteatnkiLQEKLNEMSYELKC 300
Cdd:PRK10246 379 REQLRQWQQQLTHAEQKlnalPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP-------QQKRLAQLQVAIQN 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 301 AQESSQKQDGTIQNLKETLKSRERETEELYQVIEgQNDTMAKLREMLHQSQLGQLHSSEGTS--PAQQQVALLDLQSalf 378
Cdd:PRK10246 452 VTQEQTQRNAALNEMRQRYKEKTQQLADVKTICE-QEARIKDLEAQRAQLQAGQPCPLCGSTshPAVEAYQALEPGV--- 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 379 cSQLEIQKLQRVVRQ-KERQLADAKQcvqfVEAAAHESEQQKEASwkhnQELRKALQQLQEELQNKSQQLraweaekyNE 457
Cdd:PRK10246 528 -NQSRLDALEKEVKKlGEEGAALRGQ----LDALTKQLQRDESEA----QSLRQEEQALTQQWQAVCASL--------NI 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 458 IRTQEQNIQH-LNHSLSHKEQLLQefrelLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAI----------DEKFS 526
Cdd:PRK10246 591 TLQPQDDIQPwLDAQEEHERQLRL-----LSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALagyaltlpqeDEEAS 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 527 ALEEKEKEL-----RQLRL-AVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEV--EQLSTTCQnLQWLKEEMETKF 598
Cdd:PRK10246 666 WLATRQQEAqswqqRQNELtALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVheQCLSLHSQ-LQTLQQQDVLEA 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 599 SRWQKEQESIIQQLQTSLHDrnkeveDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLL 678
Cdd:PRK10246 745 QRLQKAQAQFDTALQASVFD------DQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGL 818
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 679 QSVSTREQeSQAAAEKLVQALME---RNSEL-QALRQYLGGRD---SLMSQAPISNQQAE 731
Cdd:PRK10246 819 DLTVTVEQ-IQQELAQLAQQLREnttRQGEIrQQLKQDADNRQqqqALMQQIAQATQQVE 877
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1872-1998 |
2.17e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.47 E-value: 2.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1872 RVLREDNRRLQAQLSHVSREHSQETESLRE---ALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSL 1948
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAEleaELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1949 QENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKDSA 1998
Cdd:COG1196 315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
503-961 |
2.80e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.19 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 503 LEKLRQRIHDKAVALERAIDEKFSALEEKEKE------------LRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 570
Cdd:PRK02224 164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQieekeekdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 571 ---RAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEqesiIQQLQTSLHDRNKEVEDLSATllCKLGPGQSEIAEELCQ 647
Cdd:PRK02224 244 eehEERREELETLEAEIEDLRETIAETEREREELAEE----VRDLRERLEELEEERDDLLAE--AGLDDADAEAVEARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 648 RLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISN 727
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELR 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 728 QQAEVTPTgRLGKQTDQGSMQIPSRDDS----TSLTAK---------------------------EDVSIPRSTLGDLDT 776
Cdd:PRK02224 398 ERFGDAPV-DLGNAEDFLEELREERDELrereAELEATlrtarerveeaealleagkcpecgqpvEGSPHVETIEEDRER 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 777 VAGLEKELSNAKEELELMAKK-ER-----ESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDP 850
Cdd:PRK02224 477 VEELEAELEDLEEEVEEVEERlERaedlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 851 EDipAMERLTQEVLLLREKVASVESQGQEISgNRRQQL------LLMLEGLVDERSRLNEALQA------ERQLYSSlvk 918
Cdd:PRK02224 557 RE--AAAEAEEEAEEAREEVAELNSKLAELK-ERIESLerirtlLAAIADAEDEIERLREKREAlaelndERRERLA--- 630
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 2056392186 919 fhahpESSERDRTLQVE-----LEGAQVLRSRLEEVLGRSLERLNRLE 961
Cdd:PRK02224 631 -----EKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELR 673
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
323-711 |
3.60e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.88 E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 323 ERETEELYQVIEGQ---NDTMAKLREMLHQSQLgqlhssEGTSPAQQqvALLDLQSALFCSQleiqklQRVVRQKERQLA 399
Cdd:pfam17380 286 ERQQQEKFEKMEQErlrQEKEEKAREVERRRKL------EEAEKARQ--AEMDRQAAIYAEQ------ERMAMERERELE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 400 DAKQcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAwEAEKYNEIRTQEQNIQhlnhslshkEQLL 479
Cdd:pfam17380 352 RIRQ-----EERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQ---------RKIQ 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 480 QEFRELLQYRDNSDktlEANEMLLEKLRqrihdkavaleraidekfsalEEKEKELRQLRLAVRERDHDLERLRDVLSSN 559
Cdd:pfam17380 417 QQKVEMEQIRAEQE---EARQREVRRLE---------------------EERAREMERVRLEEQERQQQVERLRQQEEER 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 560 EATMQSMESLLRAKGLEVEqlsttcQNLQWLKEEMETKfSRWQKEQESIIQQLQTSLHDRnkevedlsatllcklgpgQS 639
Cdd:pfam17380 473 KRKKLELEKEKRDRKRAEE------QRRKILEKELEER-KQAMIEEERKRKLLEKEMEER------------------QK 527
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392186 640 EIAEELCQRLQRKERmlqdllsdRNKQVLEHEMEIQgllqsvstrEQESQAAAEKLVQALMERNSELqaLRQ 711
Cdd:pfam17380 528 AIYEEERRREAEEER--------RKQQEMEERRRIQ---------EQMRKATEERSRLEAMEREREM--MRQ 580
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
261-1005 |
4.14e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.81 E-value: 4.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 261 TQQSVSDSHLAELQEKIQQTEATNKIlQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKsrerETEELYQVIEGQNDTM 340
Cdd:TIGR00606 197 TQGQKVQEHQMELKYLKQYKEKACEI-RDQITSKEAQLESSREIVKSYENELDPLKNRLK----EIEHNLSKIMKLDNEI 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 341 AKLREMLHQSQLGQLHSSEgtspaqqqvallDLQSALFCSQLEIQKL----QRVVRQKERQLADAKQCVQFVEAAAHESE 416
Cdd:TIGR00606 272 KALKSRKKQMEKDNSELEL------------KMEKVFQGTDEQLNDLyhnhQRTVREKERELVDCQRELEKLNKERRLLN 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 417 QQKeaswkhnQELRKALQQLQEELQNKSQQLRAWEAEKY-NEIRTQEQNIQHLNHSlshkEQLLQEFRELLQYRDNSD-- 493
Cdd:TIGR00606 340 QEK-------TELLVEQGRLQLQADRHQEHIRARDSLIQsLATRLELDGFERGPFS----ERQIKNFHTLVIERQEDEak 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 494 ------KTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERD---HDLERLRDVLSSNEATMQ 564
Cdd:TIGR00606 409 taaqlcADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEgssDRILELDQELRKAERELS 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 565 SME--SLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQL-----QTSLHDRNKEVEDLSATLLCKLGP- 636
Cdd:TIGR00606 489 KAEknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdKMDKDEQIRKIKSRHSDELTSLLGy 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 637 -GQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQAL--MERNSELQALRQYL 713
Cdd:TIGR00606 569 fPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsQDEESDLERLKEEI 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 714 ggRDSLMSQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDDSTSLTAKEDVS-IPRSTLGDLDTVAGLEKELSNAKEELE 792
Cdd:TIGR00606 649 --EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISdLQSKLRLAPDKLKSTESELKKKEKRRD 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 793 LMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPE----DIPAMERLTQEVLLLRE 868
Cdd:TIGR00606 727 EMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltDVTIMERFQMELKDVER 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 869 KVASVESQGQEISGNRR-QQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERD-RTLQVELEGAQVLRSRL 946
Cdd:TIGR00606 807 KIAQQAAKLQGSDLDRTvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElKSEKLQIGTNLQRRQQF 886
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 2056392186 947 EEvlgRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEK 1005
Cdd:TIGR00606 887 EE---QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK 942
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
191-459 |
5.05e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 5.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 191 DQYTEALAQRDKRIEELNQSLAAQERLVEQLsREKQQLLHLlEEPTSMEVQPMTEelLKQQklnshettitqqsvsdshL 270
Cdd:COG3206 171 EEARKALEFLEEQLPELRKELEEAEAALEEF-RQKNGLVDL-SEEAKLLLQQLSE--LESQ------------------L 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 271 AELQEKIQQTEATNKILQEKLNEMSYELkcaqeSSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREmlhqs 350
Cdd:COG3206 229 AEARAELAEAEARLAALRAQLGSGPDAL-----PELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRA----- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 351 qlgQLHSSEGTSPAQQQVALLDLQSalfcsqlEIQKLQRVVRQKERQLADAKQcvQFVEAAAHESEQQKeaswkHNQELr 430
Cdd:COG3206 299 ---QIAALRAQLQQEAQRILASLEA-------ELEALQAREASLQAQLAQLEA--RLAELPELEAELRR-----LEREV- 360
|
250 260
....*....|....*....|....*....
gi 2056392186 431 KALQQLQEELQNKSQQLRAWEAEKYNEIR 459
Cdd:COG3206 361 EVARELYESLLQRLEEARLAEALTVGNVR 389
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
80-650 |
5.29e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.55 E-value: 5.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 80 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAE---LRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA 156
Cdd:pfam01576 181 LKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGEstdLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKN 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 157 ALVEAEKECNLELSEKLkgvtknwEDVPGDQVkpdQYTEALAQRDKRIEELN----------QSLAAQERLVEQLSREKQ 226
Cdd:pfam01576 261 NALKKIRELEAQISELQ-------EDLESERA---ARNKAEKQRRDLGEELEalkteledtlDTTAAQQELRSKREQEVT 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 227 QLLHLLEEPTSMEVQPMTEelLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQ 306
Cdd:pfam01576 331 ELKKALEEETRSHEAQLQE--MRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRK 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 307 KQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQvaLLDLQSALFCSQLEIQK 386
Cdd:pfam01576 409 KLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ--LQDTQELLQEETRQKLN 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 387 LQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQ--------------LQEELQNKSQQL--RAW 450
Cdd:pfam01576 487 LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEdagtlealeegkkrLQRELEALTQQLeeKAA 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 451 EAEKYNEIRTQEQ--------NIQHLNHSLSHKEQLLQEFRELLQYRDN-SDKTLEANEMLLEKLRQRiHDKAVALERAI 521
Cdd:pfam01576 567 AYDKLEKTKNRLQqelddllvDLDHQRQLVSNLEKKQKKFDQMLAEEKAiSARYAEERDRAEAEAREK-ETRALSLARAL 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 522 DEKFSALEEKEKELRQLRLavrerdhdleRLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEM---ETKF 598
Cdd:pfam01576 646 EEALEAKEELERTNKQLRA----------EMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELqatEDAK 715
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 2056392186 599 SRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQ 650
Cdd:pfam01576 716 LRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQ 767
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
385-606 |
5.90e-04 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 44.36 E-value: 5.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 385 QKLQRVVRQKERQLADAKqcvqfvEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEkyneirTQEQN 464
Cdd:pfam09787 14 QKAARILQSKEKLIASLK------EGSGVEGLDSSTALTLELEELRQERDLLREEIQKLRGQIQQLRTE------LQELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 465 IQHLNHSLSHKEQLlQEFRELLQYRDNSDKTLEANemlLEKLRQRIHdkavaleraidekfSALEEKEKELRQLRLAVRE 544
Cdd:pfam09787 82 AQQQEEAESSREQL-QELEEQLATERSARREAEAE---LERLQEELR--------------YLEEELRRSKATLQSRIKD 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2056392186 545 RDHDLERLRDVL---SSNEATMQSMESLLR-------AKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQE 606
Cdd:pfam09787 144 REAEIEKLRNQLtskSQSSSSQSELENRLHqltetliQKQTMLEALSTEKNSLVLQLERMEQQIKELQGEGS 215
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
416-565 |
7.19e-04 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 42.97 E-value: 7.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 416 EQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKY------NEIRTQEQNIQHLNHslsHKEQLLQEFRELLQYR 489
Cdd:pfam13851 46 EKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKDKQslknlkARLKVLEKELKDLKW---EHEVLEQRFEKVERER 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 490 DNsdkTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDL----ERLRDVLSSNEATMQS 565
Cdd:pfam13851 123 DE---LYDKFEAAIQDVQQKTGLKNLLLEKKLQALGETLEKKEAQLNEVLAAANLDPDALqavtEKLEDVLESKNQLIKD 199
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
75-334 |
7.50e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 44.56 E-value: 7.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 75 EKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHvyELLENKIQLLQEESRLAKNEAAR 154
Cdd:COG5185 282 ENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETET--GIQNLTAEIEQGQESLTENLEAI 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 155 MAALVEAEKECNLE-LSEKLKGVTKNWEDVPgdQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLE 233
Cdd:COG5185 360 KEEIENIVGEVELSkSSEELDSFKDTIESTK--ESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNE 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 234 EpTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQ 313
Cdd:COG5185 438 E-VSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVR 516
|
250 260
....*....|....*....|....*
gi 2056392186 314 NL----KETLKSRERETEELYQVIE 334
Cdd:COG5185 517 SKldqvAESLKDFMRARGYAHILAL 541
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
381-1065 |
8.66e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.57 E-value: 8.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 381 QLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQlQEELQNKSQQLRAWEAEKYNEIRT 460
Cdd:TIGR00618 200 TLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-QLKKQQLLKQLRARIEELRAQEAV 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 461 QEQNIQHLNHSlSHKEQLLQEFRELLQYRDNSDK---TLEANEMLLEKLRQriHDKAVALERAIDEKFSALEEKEkeLRQ 537
Cdd:TIGR00618 279 LEETQERINRA-RKAAPLAAHIKAVTQIEQQAQRihtELQSKMRSRAKLLM--KRAAHVKQQSSIEEQRRLLQTL--HSQ 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 538 LRLAVRERDHDLERlRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLqtslH 617
Cdd:TIGR00618 354 EIHIRDAHEVATSI-REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA----H 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 618 DRNKEVEDLSATLLCKLGPG---QSEIAEE-LCQRLQRKERMLQDLLSDRnKQVLEHEMEIQGLLQSVSTREQESQAAAE 693
Cdd:TIGR00618 429 AKKQQELQQRYAELCAAAITctaQCEKLEKiHLQESAQSLKEREQQLQTK-EQIHLQETRKKAVVLARLLELQEEPCPLC 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 694 KlvqALMERNSELQALRQyLGGRDSLMSQ---APISNQQAEVTPTGRLGKQTDQG---SMQIPSRDDSTSLTAKEDVSIP 767
Cdd:TIGR00618 508 G---SCIHPNPARQDIDN-PGPLTRRMQRgeqTYAQLETSEEDVYHQLTSERKQRaslKEQMQEIQQSFSILTQCDNRSK 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 768 RStlgdldtVAGLEKELSNAKEELELMAKKERESQMELSAlqsmmavQEEELQVQAADMESLTRNIQIKEDLIKDLQmql 847
Cdd:TIGR00618 584 ED-------IPNLQNITVRLQDLTEKLSEAEDMLACEQHA-------LLRKLQPEQDLQDVRLHLQQCSQELALKLT--- 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 848 vdpedipAMERLTQEVLLLREKVASVES-QGQEISGNRRQQLLLMLEGLVDE----RSRLNEALQAERQLYSSLVKFHAH 922
Cdd:TIGR00618 647 -------ALHALQLTLTQERVREHALSIrVLPKELLASRQLALQKMQSEKEQltywKEMLAQCQTLLRELETHIEEYDRE 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 923 -PESSERDRTLQVELEGAQVLrsrLEEVLGrSLERLNRlETLAAIGGAAAGDDTEDTSTEFTDSIEEE-AAHHSHQQLVK 1000
Cdd:TIGR00618 720 fNEIENASSSLGSDLAAREDA---LNQSLK-ELMHQAR-TVLKARTEAHFNNNEEVTAALQTGAELSHlAAEIQFFNRLR 794
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2056392186 1001 VALEKSLATVETQNPSFSPPspmGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEE 1065
Cdd:TIGR00618 795 EEDTHLLKTLEAEIGQEIPS---DEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEE 856
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1879-1981 |
9.52e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.66 E-value: 9.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1879 RRLQAQLSHVSREHS---QETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRL 1955
Cdd:TIGR02168 263 QELEEKLEELRLEVSeleEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
|
90 100
....*....|....*....|....*.
gi 2056392186 1956 QHKLVLLQQQCEEKQQLFESLQSELQ 1981
Cdd:TIGR02168 343 EEKLEELKEELESLEAELEELEAELE 368
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1809-1981 |
9.74e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 9.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1809 DLLEEHLGEIRNLRQRLEESIcinDRLREQLEHRLTSTARgrgstsnfYSQGLESipqLCNENRVLREDNRRLQAQLSHV 1888
Cdd:COG1196 263 AELEAELEELRLELEELELEL---EEAQAEEYELLAELAR--------LEQDIAR---LEERRRELEERLEELEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1889 SREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLR---EKQQEVLHFREERLSLQENDSRLQHKLVLLQQQ 1965
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAelaEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
|
170
....*....|....*.
gi 2056392186 1966 CEEKQQLFESLQSELQ 1981
Cdd:COG1196 409 EEALLERLERLEEELE 424
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
427-962 |
1.10e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 427 QELRKALQQLQEELQNKSQQLRAWE-----AEKYNEIRTQEQNIQHLNHSLSH--KEQLLQEFRELLQYRDNSDKTLEAN 499
Cdd:COG4913 231 VEHFDDLERAHEALEDAREQIELLEpirelAERYAAARERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 500 EMLLEKLRQRIHDKAVALERAIDE-KFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVE 578
Cdd:COG4913 311 LERLEARLDALREELDELEAQIRGnGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 579 QLSTTCQNLQwlkEEMETKFSRWQKEqesiIQQLQTSLHDRNKEVEDLSATLLCkLGPGQSEIAEELCQRLQRKERMLQ- 657
Cdd:COG4913 391 ALLEALEEEL---EALEEALAEAEAA----LRDLRRELRELEAEIASLERRKSN-IPARLLALRDALAEALGLDEAELPf 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 658 --DLLsdrnkQVLEHEME----IQGLLQSVSTR-----EQESQAAA--------EKLV-QALMERNSELQA--------- 708
Cdd:COG4913 463 vgELI-----EVRPEEERwrgaIERVLGGFALTllvppEHYAAALRwvnrlhlrGRLVyERVRTGLPDPERprldpdsla 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 709 -------------LRQYLGGRDSLM---SQAPISNQQAEVTPTGrLGKQtdqgsmqipsrddSTSLTAKEDVSIPRST-- 770
Cdd:COG4913 538 gkldfkphpfrawLEAELGRRFDYVcvdSPEELRRHPRAITRAG-QVKG-------------NGTRHEKDDRRRIRSRyv 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 771 LGD--LDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAA--DMESLTRNIQIKEDLIKDLQmq 846
Cdd:COG4913 604 LGFdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeiDVASAEREIAELEAELERLD-- 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 847 lvdpEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQqlllmlegLVDERSRLNEALQAERQLYSSLVKFHAHPESS 926
Cdd:COG4913 682 ----ASSDDLAALEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
570 580 590
....*....|....*....|....*....|....*...
gi 2056392186 927 ERDRTLQVELEGAQV--LRSRLEEVLGRSLERLNRLET 962
Cdd:COG4913 750 LLEERFAAALGDAVEreLRENLEERIDALRARLNRAEE 787
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
65-535 |
1.20e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.24 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 65 QVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENlnsqneaelrrqfeerqqetehvyelLENKIQLLQEE 144
Cdd:TIGR04523 243 EKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE--------------------------LEKQLNQLKSE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 145 srlakneaarmaaLVEAEKECNLELSEKLKGVTKNWEDvpgdqvKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSRE 224
Cdd:TIGR04523 297 -------------ISDLNNQKEQDWNKELKSELKNQEK------KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 225 KQQLLHLLEEPTSmEVQPMTEEllKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQES 304
Cdd:TIGR04523 358 NSEKQRELEEKQN-EIEKLKKE--NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 305 SQKQDGTIQNLKET-------LKSRERETEELYQVIEGQNDTMAKLREMLHQ---------SQLGQLhsSEGTSPAQQQV 368
Cdd:TIGR04523 435 IIKNNSEIKDLTNQdsvkeliIKNLDNTRESLETQLKVLSRSINKIKQNLEQkqkelkskeKELKKL--NEEKKELEEKV 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 369 ALLDLQSALFCSqlEIQKLQRVVRQKERQLADAkqcvqfveaaahESEQQKEASWKHNQELRKALQQLQ---EELQNKSQ 445
Cdd:TIGR04523 513 KDLTKKISSLKE--KIEKLESEKKEKESKISDL------------EDELNKDDFELKKENLEKEIDEKNkeiEELKQTQK 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 446 QLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDE-- 523
Cdd:TIGR04523 579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEir 658
|
490
....*....|...
gi 2056392186 524 -KFSALEEKEKEL 535
Cdd:TIGR04523 659 nKWPEIIKKIKES 671
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
83-727 |
1.48e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 83 EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE---RQQETEHVYELLENKIQLLQEESRLAknEAARMAALV 159
Cdd:PTZ00121 1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEakkDAEEAKKAEEERNNEEIRKFEEARMA--HFARRQAAI 1272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 160 EAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSME 239
Cdd:PTZ00121 1273 KAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 240 VQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKlNEMSYELKCAQESSQKQDGTIQNLKETL 319
Cdd:PTZ00121 1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-KKKADELKKAAAAKKKADEAKKKAEEKK 1431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 320 KSRE---------------------RETEELYQVIE---------GQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVA 369
Cdd:PTZ00121 1432 KADEakkkaeeakkadeakkkaeeaKKAEEAKKKAEeakkadeakKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 370 LLDLQSALfcsqlEIQKLQRVVRQKERQLADAKQCVQFVEAAaheSEQQKEASWKHNQELRKALQQLQEELQNKSQQLRA 449
Cdd:PTZ00121 1512 ADEAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKA---DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA 1583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 450 WEAEKYNEIRTQEQNIQHLNHSLSHKEQL---------LQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERA 520
Cdd:PTZ00121 1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAkkaeeakikAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 521 IDEKFSALEEKEK--ELRQLRLAVRERDHDLER-LRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETK 597
Cdd:PTZ00121 1664 AEEAKKAEEDKKKaeEAKKAEEDEKKAAEALKKeAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK 1743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 598 F----SRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLcklgpgQSEIAEELCQRLQRKERMLQDLLSdrNKQVLEhEME 673
Cdd:PTZ00121 1744 KkaeeAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI------EEELDEEDEKRRMEVDKKIKDIFD--NFANII-EGG 1814
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2056392186 674 IQGLLQSVSTREQESQAAAEKLVQALMERNsELQALRQYLGGRDSLMSQAPISN 727
Cdd:PTZ00121 1815 KEGNLVINDSKEMEDSAIKEVADSKNMQLE-EADAFEKHKFNKNNENGEDGNKE 1867
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
362-545 |
1.51e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 362 SPAQQQVALLDLQSALfcsqLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEaswkhnqELRKALQQLQEELQ 441
Cdd:COG1579 1 AMPEDLRALLDLQELD----SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELE-------DLEKEIKRLELEIE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 442 NKSQQLRAWEaEKYNEIRTQEQnIQHLNHSLSH----KEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIhdkaVAL 517
Cdd:COG1579 70 EVEARIKKYE-EQLGNVRNNKE-YEALQKEIESlkrrISDLEDEILELMERIEELEEELAELEAELAELEAEL----EEK 143
|
170 180
....*....|....*....|....*...
gi 2056392186 518 ERAIDEKFSALEEKEKELRQLRLAVRER 545
Cdd:COG1579 144 KAELDEELAELEAELEELEAEREELAAK 171
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
256-722 |
1.93e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 43.27 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 256 HETTITQQSVSDSH-------LAELQEKIQQTEATNKILQEKLNEMSyelkcAQESSQKQDgtIQNLKETLKSRERETEE 328
Cdd:pfam10174 270 REEEIKQMEVYKSHskfmknkIDQLKQELSKKESELLALQTKLETLT-----NQNSDCKQH--IEVLKESLTAKEQRAAI 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 329 LYQVIEGQNDTMAKLREMLH--QSQLGQLHSSEGTspaqQQVALLDLQSALFCS-------QLEIQKLQRVVRQKERQLA 399
Cdd:pfam10174 343 LQTEVDALRLRLEEKESFLNkkTKQLQDLTEEKST----LAGEIRDLKDMLDVKerkinvlQKKIENLQEQLRDKDKQLA 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 400 DAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLL 479
Cdd:pfam10174 419 GLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSL 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 480 QEFRELLQ-------YRDNSDKTLEAN-------EMLLEKLRQRIHDKAVAlERAIDEKFSALEEKEKELRQLRLAVRER 545
Cdd:pfam10174 499 IDLKEHASslassglKKDSKLKSLEIAveqkkeeCSKLENQLKKAHNAEEA-VRTNPEINDRIRLLEQEVARYKEESGKA 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 546 DHDLERLRDVL-------SSNEATMQSMESLLRAKGLEveqLSTTCQNLQWLKEEMETKfsrwqkeqesIIQQLQTSLHD 618
Cdd:pfam10174 578 QAEVERLLGILrevenekNDKDKKIAELESLTLRQMKE---QNKKVANIKHGQQEMKKK----------GAQLLEEARRR 644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 619 RNKEVEDLSATLLCKLGPGQSEIAEEL----------CQRLQRKERMLQDLLSDRNKQVLEH-EMEIQGLLQSVStrEQE 687
Cdd:pfam10174 645 EDNLADNSQQLQLEELMGALEKTRQELdatkarlsstQQSLAEKDGHLTNLRAERRKQLEEIlEMKQEALLAAIS--EKD 722
|
490 500 510
....*....|....*....|....*....|....*.
gi 2056392186 688 SQAAAEKLVQALMERNS-ELQALRQYlggRDSLMSQ 722
Cdd:pfam10174 723 ANIALLELSSSKKKKTQeEVMALKRE---KDRLVHQ 755
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
406-697 |
2.33e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 43.35 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 406 QFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNksqqlraweAEK----YNEIRTQEqnIQHLNHSLSHKEQLLQE 481
Cdd:PLN02939 103 QRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQN---------AEKnillLNQARLQA--LEDLEKILTEKEALQGK 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 482 FREL---LQYRDNSDKT-------LEANEMLLEKLRQRIHDKAV---ALERAIDEKFSALEEKEKELRQLRLAVR----- 543
Cdd:PLN02939 172 INILemrLSETDARIKLaaqekihVEILEEQLEKLRNELLIRGAtegLCVHSLSKELDVLKEENMLLKDDIQFLKaelie 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 544 -----ERDHDLERLRDVLssnEATMQSMESLLRAKGLEVEQLSTTCQNLQWLK-EEMETKFSRWQKEQESIIQQLQTSlH 617
Cdd:PLN02939 252 vaeteERVFKLEKERSLL---DASLRELESKFIVAQEDVSKLSPLQYDCWWEKvENLQDLLDRATNQVEKAALVLDQN-Q 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 618 DRNKEVEDLSATLlckLGPGQSEIAEELCQRLQRKERMLQDLLsdrnkQVLEHEMEIQGLLQSVSTreQESQAAAEKLVQ 697
Cdd:PLN02939 328 DLRDKVDKLEASL---KEANVSKFSSYKVELLQQKLKLLEERL-----QASDHEIHSYIQLYQESI--KEFQDTLSKLKE 397
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1808-1981 |
2.43e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1808 ADLLEEHLGEIRNLRQRLEesicindRLREQLEHrltstargrgstsnfysqgLESIPQLCNENRVLREDNRRLQAQLSH 1887
Cdd:COG4913 227 ADALVEHFDDLERAHEALE-------DAREQIEL-------------------LEPIRELAERYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1888 VSREHSQ-ETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEvlhfreerlsLQEND----SRLQHKLVLL 1962
Cdd:COG4913 281 LRLWFAQrRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ----------IRGNGgdrlEQLEREIERL 350
|
170
....*....|....*....
gi 2056392186 1963 QQQCEEKQQLFESLQSELQ 1981
Cdd:COG4913 351 ERELEERERRRARLEALLA 369
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
67-476 |
2.71e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 67 QTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE------------------ 128
Cdd:pfam15921 397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNEslekvssltaqlestkem 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 129 --HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELS----------EKLKGVTKNWEDVPGDQVKPDQYTEA 196
Cdd:pfam15921 477 lrKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITklrsrvdlklQELQHLKNEGDHLRNVQTECEALKLQ 556
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 197 LAQRDKRIEELNQSLAAQERLVEQLSR-------EKQQLLHLLEEpTSMEVQPMteELLKQQKlnshettitqqsvsDSH 269
Cdd:pfam15921 557 MAEKDKVIEILRQQIENMTQLVGQHGRtagamqvEKAQLEKEIND-RRLELQEF--KILKDKK--------------DAK 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 270 LAELQEKIQQTEATNKILqekLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEElYQVI--------EGQNDTMA 341
Cdd:pfam15921 620 IRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSED-YEVLkrnfrnksEEMETTTN 695
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 342 KLREMLH--QSQLGQ----LHSSEGTSPAQQQVAlLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHES 415
Cdd:pfam15921 696 KLKMQLKsaQSELEQtrntLKSMEGSDGHAMKVA-MGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKL 774
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2056392186 416 EQ-------QKEASWKHNQELRKALQQLQEELQNKSQQLRAWE---AEKYNEIRTQEQNIQH--LNHSLSHKE 476
Cdd:pfam15921 775 SQelstvatEKNKMAGELEVLRSQERRLKEKVANMEVALDKASlqfAECQDIIQRQEQESVRlkLQHTLDVKE 847
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1811-1981 |
2.80e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.13 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1811 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGS-----------------TSNFYSQGLESI--------- 1864
Cdd:TIGR02169 714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENvkselkelearieeleeDLHKLEEALNDLearlshsri 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1865 PQLCNENRVLREDNRRLQAQLSHVSREHSQETEsLREALLSSRSHLQELEKELEHQKVERQQLLEDLR-----------E 1933
Cdd:TIGR02169 794 PEIQAELSKLEEEVSRIEARLREIEQKLNRLTL-EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkeeleeeleE 872
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2056392186 1934 KQQEVLHFREERLSLQENDSRLQHKLVLLQ---QQCEEKQQLFESLQSELQ 1981
Cdd:TIGR02169 873 LEAALRDLESRLGDLKKERDELEAQLRELErkiEELEAQIEKKRKRLSELK 923
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
65-309 |
2.89e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.98 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 65 QVQTQALRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEerqqetehvyellenKIQLLQEE 144
Cdd:PRK11281 63 QDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLS---------------TLSLRQLE 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 145 SRLAKneaaRMAALVEAEKECNlelseklkgvTKNWEDVpGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSRE 224
Cdd:PRK11281 128 SRLAQ----TLDQLQNAQNDLA----------EYNSQLV-SLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 225 KQQLLHLleEPTSMEVQpmteeLLKQQKLNSHETTItqQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYEL--KCAQ 302
Cdd:PRK11281 193 QRVLLQA--EQALLNAQ-----NDLQRKSLEGNTQL--QDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLseKTVQ 263
|
....*..
gi 2056392186 303 ESSQKQD 309
Cdd:PRK11281 264 EAQSQDE 270
|
|
| HAUS5 |
pfam14817 |
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. ... |
1866-1950 |
2.91e-03 |
|
HAUS augmin-like complex subunit 5; This family includes HAUS augmin-like complex subunit 5. The HAUS augmin-like complex contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis.
Pssm-ID: 464332 [Multi-domain] Cd Length: 643 Bit Score: 42.73 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1866 QLCNENRVLREDNRRLQAQL----------SHVSREHSQETESLREA---------LLSSRSHLQELEKELEHQKVERQQ 1926
Cdd:pfam14817 317 QFLNELAETRSRCQQLQARLqglkdeaeleSLGIGDTSQNDSLLRQVlelelqaagLAASRDTLRSECQQLNKLARERQE 396
|
90 100
....*....|....*....|....
gi 2056392186 1927 LLEDLREKQQEVLHFREERLSLQE 1950
Cdd:pfam14817 397 ALRSLQKKWQRILDFRQLVSELQE 420
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
883-1152 |
3.20e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 3.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 883 NRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVkfHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLEt 962
Cdd:TIGR02168 239 EELEELQEELKEAEEELEELTAELQELEEKLEELR--LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE- 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 963 laaiggaaagddteDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQ-------NPSFSPPSPMGGDSNRCLQEEM 1035
Cdd:TIGR02168 316 --------------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEElesleaeLEELEAELEELESRLEELEEQL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1036 LHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFS-SVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVE 1114
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRrERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEE 461
|
250 260 270
....*....|....*....|....*....|....*...
gi 2056392186 1115 TVVTKEGLSEsSLQAEFRKLQGKLKNAHNIINLLKEQL 1152
Cdd:TIGR02168 462 ALEELREELE-EAEQALDAAERELAQLQARLDSLERLQ 498
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
476-706 |
3.26e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 476 EQLLQEFRELLQYRDNSDKTLEANEML--LEKLRQRIHDKAVALE--RAIDEKFS------ALEEKEKELRQLRLAVRER 545
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLepIRELAERYAAARERLAelEYLRAALRlwfaqrRLELLEAELEELRAELARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 546 DHDLERLRDVLSSNEATMQSMESLLRAKGLE-VEQLSttcQNLQWLKEEMETKFSRWQkEQESIIQQLQTSLHDRNKEVE 624
Cdd:COG4913 308 EAELERLEARLDALREELDELEAQIRGNGGDrLEQLE---REIERLERELEERERRRA-RLEALLAALGLPLPASAEEFA 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 625 DLSATLlcklgPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNS 704
Cdd:COG4913 384 ALRAEA-----AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEA 458
|
..
gi 2056392186 705 EL 706
Cdd:COG4913 459 EL 460
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
71-523 |
3.28e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.74 E-value: 3.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 71 LRDFEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR---------RQFEERQQETEHVYELLENKIQLL 141
Cdd:PRK03918 285 LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKeleekeerlEELKKKLKELEKRLEELEERHELY 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 142 QEesrlAKNEAARMAALVEAEKECNLE-LSEKLKGVTKNWEDVpgdQVKPDQYTEALAQRDKRIEELNQSLAA------- 213
Cdd:PRK03918 365 EE----AKAKKEELERLKKRLTGLTPEkLEKELEELEKAKEEI---EEEISKITARIGELKKEIKELKKAIEElkkakgk 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 214 ------------QERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDsHLAELQEKiqqte 281
Cdd:PRK03918 438 cpvcgrelteehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE-QLKELEEK----- 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 282 aTNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ------SQLGQL 355
Cdd:PRK03918 512 -LKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEleelgfESVEEL 590
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 356 HS--SEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQfvEAAAHESEQQKEASWKHNQELRKAL 433
Cdd:PRK03918 591 EErlKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE--ELRKELEELEKKYSEEEYEELREEY 668
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 434 QQLQEELQNKSQQLRAWEaekyNEIRTQEQNIQHLNHSLSHKEQLLQEFRELlqyrdnsDKTLEANEMLLEKLRQRihdK 513
Cdd:PRK03918 669 LELSRELAGLRAELEELE----KRREEIKKTLEKLKEELEEREKAKKELEKL-------EKALERVEELREKVKKY---K 734
|
490
....*....|
gi 2056392186 514 AVALERAIDE 523
Cdd:PRK03918 735 ALLKERALSK 744
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
397-713 |
3.75e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.59 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 397 QLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQlraweaekyneIRTQEQNIQHLNHSLSHKE 476
Cdd:PRK11281 25 AFARAASNGDLPTEADVQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDK-----------IDRQKEETEQLKQQLAQAP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 477 QLLQEF-RELLQYRDNSDKTLEANemlLEKLRQRihdkavALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDV 555
Cdd:PRK11281 94 AKLRQAqAELEALKDDNDEETRET---LSTLSLR------QLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 556 LSSNEATMQSMESLLRAKGLEVEQLSTTCQNLqwlkeemetkfsrWQKEQESIiqQLQTSLhdRNKEVEdlSATLLCKLG 635
Cdd:PRK11281 165 LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL-------------LQAEQALL--NAQNDL--QRKSLE--GNTQLQDLL 225
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2056392186 636 PGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMeiqgllQSVSTREQESQAAAEKLVQALMERNSELQalrQYL 713
Cdd:PRK11281 226 QKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEKTV------QEAQSQDEAARIQANPLVAQELEINLQLS---QRL 294
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
69-741 |
4.21e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.52 E-value: 4.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 69 QALRDFEKNIE--LKVEVESLKRE-LQDKKQHLDKTWADVENLnsqnEAELRRQFEERQQETEHVYELLENKIQLLQEES 145
Cdd:pfam12128 231 QAIAGIMKIRPefTKLQQEFNTLEsAELRLSHLHFGYKSDETL----IASRQEERQETSAELNQLLRTLDDQWKEKRDEL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 146 RLakneaaRMAALVEAEKECNLELsEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDkrIEELNQSLAAQERLVEQLSREK 225
Cdd:pfam12128 307 NG------ELSAADAAVAKDRSEL-EALEDQHGAFLDADIETAAADQEQLPSWQSE--LENLEERLKALTGKHQDVTAKY 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 226 QQLLHLLEEPTSMEVqpmteELLKQQKLNSHETTITQQSVSDSHL----AELQEKIQQTEATNKILQEKLNEMSYELKCA 301
Cdd:pfam12128 378 NRRRSKIKEQNNRDI-----AGIKDKLAKIREARDRQLAVAEDDLqaleSELREQLEAGKLEFNEEEYRLKSRLGELKLR 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 302 QESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQS-QLGQLHSSEGTSPAQQQVALLDLQSALFCS 380
Cdd:pfam12128 453 LNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRdQASEALRQASRRLEERQSALDELELQLFPQ 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 381 Q---------------------LEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEE 439
Cdd:pfam12128 533 AgtllhflrkeapdweqsigkvISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEA 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 440 LQnkSQQLRAWEAEKynEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRdnsdktleANEMLLEKLRqrihdKAVALER 519
Cdd:pfam12128 613 LQ--SAREKQAAAEE--QLVQANGELEKASREETFARTALKNARLDLRRL--------FDEKQSEKDK-----KNKALAE 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 520 AIDEKFSALEEKEKELRQLrlavrERDHD--LERLRDVLSSNEATMQsmesllrAKGLEVEqlSTTCQNLQWLKEEMETK 597
Cdd:pfam12128 676 RKDSANERLNSLEAQLKQL-----DKKHQawLEEQKEQKREARTEKQ-------AYWQVVE--GALDAQLALLKAAIAAR 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 598 FSRWQKEQESIIQQLQTSL----------HDRNKEVEDLSATLLCKLGPGQSEIAEELCQR---LQRKERmLQDLLSDRN 664
Cdd:pfam12128 742 RSGAKAELKALETWYKRDLaslgvdpdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQetwLQRRPR-LATQLSNIE 820
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 665 KQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMSQAPISNQQAEVTPTGRLGKQ 741
Cdd:pfam12128 821 RAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLED 897
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
74-494 |
4.40e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.25 E-value: 4.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 74 FEKNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEER------QQETEHVYELLENKIQLLQEESRL 147
Cdd:COG5185 113 EWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKdifgklTQELNQNLKKLEIFGLTLGLLKGI 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 148 AKNEAARMAALVEAEKECNLELS-----------------EKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK-------- 202
Cdd:COG5185 193 SELKKAEPSGTVNSIKESETGNLgsestllekakeiinieEALKGFQDPESELEDLAQTSDKLEKLVEQNTDlrleklge 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 203 ---RIEELNQSLAAQERLVEQLSREkqqllhlleeptsmevqpmTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQ 279
Cdd:COG5185 273 naeSSKRLNENANNLIKQFENTKEK-------------------IAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRE 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 280 TEATNKILQEKLNEmsyelkcAQESSQKQDGTIQNLKETLkSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHsse 359
Cdd:COG5185 334 TETGIQNLTAEIEQ-------GQESLTENLEAIKEEIENI-VGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRG--- 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 360 gtspaQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQ-------CVQFVEAAAHESEQQK--EASWKHNQELR 430
Cdd:COG5185 403 -----YAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKllnelisELNKVMREADEESQSRleEAYDEINRSVR 477
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 431 KALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEF---RELLQYRDNSDK 494
Cdd:COG5185 478 SKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFmraRGYAHILALENL 544
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
767-961 |
4.45e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 4.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 767 PRSTLGDLDTVAGLEKELSNAKEELELmAKKERESQMELSALQSMMAVQEEELQVQAADMESLT-----RNIQIKEDLIK 841
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALED-AREQIELLEPIRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 842 DLQMQLVDPEDipAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLvkfHA 921
Cdd:COG4913 299 ELRAELARLEA--ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL---GL 373
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2056392186 922 HPESSERD-----RTLQVELEGAQVLRSRLEEVLGRSLERLNRLE 961
Cdd:COG4913 374 PLPASAEEfaalrAEAAALLEALEEELEALEEALAEAEAALRDLR 418
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
61-337 |
4.87e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 61 EKPPQVQTQALRDFEKNIELKvEVESLKRELQDKKQHLdktWADVENLNSQNEAELRR-QFEERQQETEHV-YELLENKI 138
Cdd:pfam17380 299 ERLRQEKEEKAREVERRRKLE-EAEKARQAEMDRQAAI---YAEQERMAMERERELERiRQEERKRELERIrQEEIAMEI 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 139 QLLQEESRLA-----KNEAARMaalvEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQyTEALAQRDKRIEELNQSLAA 213
Cdd:pfam17380 375 SRMRELERLQmerqqKNERVRQ----ELEAARKVKILEEERQRKIQQQKVEMEQIRAEQ-EEARQREVRRLEEERAREME 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 214 QERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQT-------EATNKI 286
Cdd:pfam17380 450 RVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKllekemeERQKAI 529
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2056392186 287 LQEKLNEMSYELKCAQESS------QKQDGTIQNLKETLKSRERETEELYQVIEGQN 337
Cdd:pfam17380 530 YEEERRREAEEERRKQQEMeerrriQEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
73-314 |
5.07e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.15 E-value: 5.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 73 DFEKNIELKVEVESLKRELqDKKQHLDKTWADVEnLNSQNEaELRRQFEERQQETEHVYELLEnKIQLLQEEsrLAKNEA 152
Cdd:PLN03229 519 EFNKRLSRAPNYLSLKYKL-DMLNEFSRAKALSE-KKSKAE-KLKAEINKKFKEVMDRPEIKE-KMEALKAE--VASSGA 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 153 ARMAAL--------VEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKrIEELNqslaaqerlvEQLSRE 224
Cdd:PLN03229 593 SSGDELdddlkekvEKMKKEIELELAGVLKSMGLEVIGVTKKNKDTAEQTPPPNLQEK-IESLN----------EEINKK 661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 225 KQQLLHlleeptSMEVQPMTEELlkqqKLNSHETTITQQSVSDSHLAELQEKIQQ--TEATNKI-LQEKLNEMSYELKCA 301
Cdd:PLN03229 662 IERVIR------SSDLKSKIELL----KLEVAKASKTPDVTEKEKIEALEQQIKQkiAEALNSSeLKEKFEELEAELAAA 731
|
250
....*....|...
gi 2056392186 302 QESSQKQDGTIQN 314
Cdd:PLN03229 732 RETAAESNGSLKN 744
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
437-711 |
6.01e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.08 E-value: 6.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 437 QEELQNKSQQLRAWEaEKYNEIRTQEQNIQHLNHSLSHKEQLLQEfrellQYRDNSDKTLEANEMlleklRQRIHDKAVA 516
Cdd:pfam01576 4 EEEMQAKEEELQKVK-ERQQKAESELKELEKKHQQLCEEKNALQE-----QLQAETELCAEAEEM-----RARLAARKQE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 517 LERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMEsllrakgLEVEQLSTTCQNLQ---WLKEE 593
Cdd:pfam01576 73 LEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ-------LEKVTTEAKIKKLEediLLLED 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 594 METKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSatllcKLGPGQSEIAEELCQRLQRKERMLQDL----------LSDR 663
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSLS-----KLKNKHEAMISDLEERLKKEEKGRQELekakrklegeSTDL 220
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2056392186 664 NKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQ 711
Cdd:pfam01576 221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1808-1995 |
6.24e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.97 E-value: 6.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1808 ADLLEEHLGEIRNLRQRLEESICINDRLREQLEhRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSH 1887
Cdd:TIGR02168 704 RKELEELEEELEQLRKELEELSRQISALRKDLA-RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1888 VSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCE 1967
Cdd:TIGR02168 783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
|
170 180
....*....|....*....|....*...
gi 2056392186 1968 EKQQLFESLQSELQIYEALYGNSKKGLK 1995
Cdd:TIGR02168 863 ELEELIEELESELEALLNERASLEEALA 890
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1811-1980 |
6.50e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.97 E-value: 6.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1811 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGSTSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSR 1890
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1891 EHSQETE---SLREALLSSRSHLQELEKELEHQKVERQQ-------LLEDLREKQQEVLHFREERLSLQENDSRLQHKLV 1960
Cdd:TIGR02168 846 QIEELSEdieSLAAEIEELEELIEELESELEALLNERASleealalLRSELEELSEELRELESKRSELRRELEELREKLA 925
|
170 180
....*....|....*....|
gi 2056392186 1961 LLQQQCEEKQQLFESLQSEL 1980
Cdd:TIGR02168 926 QLELRLEGLEVRIDNLQERL 945
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
430-626 |
7.14e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 7.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 430 RKALQQLQEELQNKSQQLRAWEAEKyNEIRTQEQNIQhlnhslshkeQLLQEFRELLQYRDNSDKTLEANEML--LEKLR 507
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERL-EALEAELDALQ----------ERREALQRLAEYSWDEIDVASAEREIaeLEAEL 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 508 QRI---HDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAkgLEVEQLSTTC 584
Cdd:COG4913 678 ERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL--ELRALLEERF 755
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2056392186 585 QNLqwLKEEMETKFSRWQKEQesiIQQLQTSLHDRNKEVEDL 626
Cdd:COG4913 756 AAA--LGDAVERELRENLEER---IDALRARLNRAEEELERA 792
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
1869-1984 |
7.57e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 39.89 E-value: 7.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1869 NENRVLREDNRRLQAQLSHVSREHsQETESLREALLSSRSHLQEL--EKELEhqkvERQQLLEDLREKQQEVLHFREERL 1946
Cdd:pfam15619 67 EEVRVLRERLRRLQEKERDLERKL-KEKEAELLRLRDQLKRLEKLseDKNLA----EREELQKKLEQLEAKLEDKDEKIQ 141
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2056392186 1947 SLQE----NDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYE 1984
Cdd:pfam15619 142 DLERklelENKSFRRQLAAEKKKHKEAQEEVKILQEEIERLQ 183
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1811-1981 |
9.59e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.20 E-value: 9.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1811 LEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTA--RGRGSTSNFYSQGLESIPQLCNENRvlrEDNRRLQAQLShv 1888
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELEslEAELEELEAELEELESRLEELEEQL---ETLRSKVAQLE-- 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 1889 srehsQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFR-----EERLSLQENDSRLQHKLVLLQ 1963
Cdd:TIGR02168 393 -----LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEleeleEELEELQEELERLEEALEELR 467
|
170
....*....|....*...
gi 2056392186 1964 QQCEEKQQLFESLQSELQ 1981
Cdd:TIGR02168 468 EELEEAEQALDAAERELA 485
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
113-695 |
9.80e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.31 E-value: 9.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 113 EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEkecnlELSEKLKGVTKNWEDVPGDqvkpdq 192
Cdd:pfam01576 11 EEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAE-----EMRARLAARKQELEEILHE------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 193 yteaLAQRDKRIEELNQSLAAQERlveqlsrEKQQLLHLLEEPtsmevqpMTEELLKQQKLNSHETTItqqsvsDSHLAE 272
Cdd:pfam01576 80 ----LESRLEEEEERSQQLQNEKK-------KMQQHIQDLEEQ-------LDEEEAARQKLQLEKVTT------EAKIKK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 273 LQEKIQQTEATN-------KILQEKLNEMSYELKCAQESSQ-------KQDGTIQNLKETLKSRE---RETEELYQVIEG 335
Cdd:pfam01576 136 LEEDILLLEDQNsklskerKLLEERISEFTSNLAEEEEKAKslsklknKHEAMISDLEERLKKEEkgrQELEKAKRKLEG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 336 QndtmaklremlhqsqlgqlhssegTSPAQQQVALLdlqsalfcsQLEIQKLQRVVRQKERQLADAkqcvqfvEAAAHES 415
Cdd:pfam01576 216 E------------------------STDLQEQIAEL---------QAQIAELRAQLAKKEEELQAA-------LARLEEE 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 416 EQQKEASWKHNQELRKALQQLQEELQ------NKSQQLRAWEAEKYNEIRTQ------------------EQNIQHLNHS 471
Cdd:pfam01576 256 TAQKNNALKKIRELEAQISELQEDLEseraarNKAEKQRRDLGEELEALKTEledtldttaaqqelrskrEQEVTELKKA 335
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 472 LSHK----EQLLQEFREllqyrdnsdKTLEANEMLLEKLRQRIHDKAvALERAIDEKFSALEEKEKELRQLRLAVRERDH 547
Cdd:pfam01576 336 LEEEtrshEAQLQEMRQ---------KHTQALEELTEQLEQAKRNKA-NLEKAKQALESENAELQAELRTLQQAKQDSEH 405
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 548 DLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQT------------- 614
Cdd:pfam01576 406 KRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtqellqeetrqkl 485
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2056392186 615 SLHDRNKEVEDLSATLLcklgpGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGL----------LQSVSTR 684
Cdd:pfam01576 486 NLSTRLRQLEDERNSLQ-----EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALeegkkrlqreLEALTQQ 560
|
650
....*....|.
gi 2056392186 685 EQESQAAAEKL 695
Cdd:pfam01576 561 LEEKAAAYDKL 571
|
|
| |
