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pre-mRNA-processing factor 40 homolog A isoform 9 [Homo sapiens]
PRP40 family protein( domain architecture ID 1003925)
PRP40 family protein similar to Homo sapiens pre-mRNA-processing factor 40 homolog A that binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 super family | cl34905 | Splicing factor [RNA processing and modification]; |
110-755 | 6.73e-47 | ||||||||||
Splicing factor [RNA processing and modification]; The actual alignment was detected with superfamily member COG5104: Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 177.58 E-value: 6.73e-47
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Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
110-755 | 6.73e-47 | ||||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 177.58 E-value: 6.73e-47
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
350-399 | 7.38e-15 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 69.41 E-value: 7.38e-15
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
119-146 | 2.45e-11 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 58.69 E-value: 2.45e-11
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
119-146 | 7.77e-11 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 57.61 E-value: 7.77e-11
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PHA03255 | PHA03255 | BDLF3; Provisional |
200-342 | 1.55e-04 | ||||||||||
BDLF3; Provisional Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 44.12 E-value: 1.55e-04
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Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
110-755 | 6.73e-47 | ||||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 177.58 E-value: 6.73e-47
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
350-399 | 7.38e-15 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 69.41 E-value: 7.38e-15
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
119-146 | 2.45e-11 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 58.69 E-value: 2.45e-11
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
119-144 | 4.00e-11 | ||||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 58.29 E-value: 4.00e-11
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
119-146 | 7.77e-11 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 57.61 E-value: 7.77e-11
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
349-402 | 1.06e-09 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 54.89 E-value: 1.06e-09
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WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
157-187 | 1.91e-08 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 50.60 E-value: 1.91e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
703-757 | 2.00e-08 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 51.42 E-value: 2.00e-08
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WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
156-187 | 2.07e-08 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 50.68 E-value: 2.07e-08
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WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
159-185 | 6.73e-08 | ||||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 49.04 E-value: 6.73e-08
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FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
483-542 | 2.30e-06 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 45.26 E-value: 2.30e-06
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
704-755 | 1.57e-05 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 42.83 E-value: 1.57e-05
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PHA03255 | PHA03255 | BDLF3; Provisional |
200-342 | 1.55e-04 | ||||||||||
BDLF3; Provisional Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 44.12 E-value: 1.55e-04
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alt | PHA02566 | ADP-ribosyltransferase; Provisional |
308-513 | 3.57e-03 | ||||||||||
ADP-ribosyltransferase; Provisional Pssm-ID: 222881 [Multi-domain] Cd Length: 684 Bit Score: 41.27 E-value: 3.57e-03
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FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
567-623 | 9.59e-03 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 35.13 E-value: 9.59e-03
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Blast search parameters | ||||
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