![](files/infoQ.gif)
pre-mRNA-processing factor 40 homolog A isoform 11 [Homo sapiens]
PRP40 family protein( domain architecture ID 1003925)
PRP40 family protein similar to Homo sapiens pre-mRNA-processing factor 40 homolog A that binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 super family | cl34905 | Splicing factor [RNA processing and modification]; |
54-713 | 1.31e-45 | ||||||||||
Splicing factor [RNA processing and modification]; The actual alignment was detected with superfamily member COG5104: Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 173.34 E-value: 1.31e-45
|
||||||||||||||
Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
54-713 | 1.31e-45 | ||||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 173.34 E-value: 1.31e-45
|
||||||||||||||
FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
312-361 | 1.38e-14 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 68.64 E-value: 1.38e-14
|
||||||||||||||
WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
63-90 | 2.10e-11 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 59.08 E-value: 2.10e-11
|
||||||||||||||
WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
63-90 | 6.60e-11 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 57.61 E-value: 6.60e-11
|
||||||||||||||
PHA03255 | PHA03255 | BDLF3; Provisional |
162-304 | 1.61e-04 | ||||||||||
BDLF3; Provisional Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 44.12 E-value: 1.61e-04
|
||||||||||||||
Name | Accession | Description | Interval | E-value | ||||||||||
PRP40 | COG5104 | Splicing factor [RNA processing and modification]; |
54-713 | 1.31e-45 | ||||||||||
Splicing factor [RNA processing and modification]; Pssm-ID: 227435 [Multi-domain] Cd Length: 590 Bit Score: 173.34 E-value: 1.31e-45
|
||||||||||||||
FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
312-361 | 1.38e-14 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 68.64 E-value: 1.38e-14
|
||||||||||||||
WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
63-90 | 2.10e-11 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 59.08 E-value: 2.10e-11
|
||||||||||||||
WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
63-88 | 3.63e-11 | ||||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 58.29 E-value: 3.63e-11
|
||||||||||||||
WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
63-90 | 6.60e-11 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 57.61 E-value: 6.60e-11
|
||||||||||||||
FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
311-364 | 2.09e-09 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 54.12 E-value: 2.09e-09
|
||||||||||||||
WW | cd00201 | Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ... |
101-131 | 1.68e-08 | ||||||||||
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs. Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 50.60 E-value: 1.68e-08
|
||||||||||||||
WW | smart00456 | Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ... |
100-131 | 1.81e-08 | ||||||||||
Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides. Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 50.68 E-value: 1.81e-08
|
||||||||||||||
FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
661-715 | 3.79e-08 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 50.26 E-value: 3.79e-08
|
||||||||||||||
WW | pfam00397 | WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ... |
103-129 | 6.18e-08 | ||||||||||
WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro. Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 49.04 E-value: 6.18e-08
|
||||||||||||||
FF | smart00441 | Contains two conserved F residues; A novel motif that often accompanies WW domains. Often ... |
445-504 | 4.15e-06 | ||||||||||
Contains two conserved F residues; A novel motif that often accompanies WW domains. Often contains two conserved Phe (F) residues. Pssm-ID: 128718 [Multi-domain] Cd Length: 55 Bit Score: 44.49 E-value: 4.15e-06
|
||||||||||||||
FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
662-713 | 2.42e-05 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 42.44 E-value: 2.42e-05
|
||||||||||||||
PHA03255 | PHA03255 | BDLF3; Provisional |
162-304 | 1.61e-04 | ||||||||||
BDLF3; Provisional Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 44.12 E-value: 1.61e-04
|
||||||||||||||
FF | pfam01846 | FF domain; This domain has been predicted to be involved in protein-protein interaction. This ... |
529-581 | 8.85e-04 | ||||||||||
FF domain; This domain has been predicted to be involved in protein-protein interaction. This domain was recently shown to bind the hyperphosphorylated C-terminal repeat domain of RNA polymerase II, confirming its role in protein-protein interactions. Pssm-ID: 426471 [Multi-domain] Cd Length: 50 Bit Score: 37.82 E-value: 8.85e-04
|
||||||||||||||
alt | PHA02566 | ADP-ribosyltransferase; Provisional |
270-475 | 5.12e-03 | ||||||||||
ADP-ribosyltransferase; Provisional Pssm-ID: 222881 [Multi-domain] Cd Length: 684 Bit Score: 40.50 E-value: 5.12e-03
|
||||||||||||||
Blast search parameters | ||||
|