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Conserved domains on  [gi|2077863211|ref|NP_001382764|]
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zinc finger protein 846 isoform 7 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 18089714)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60|1.10.287.1360
Gene Ontology:  GO:0008270|GO:0003677|GO:0003700|GO:0005515|GO:0001217
PubMed:  11361095|22803940|30718982|10940247|12665246|11179890|8183940|2023909|8183939|10748030|27867147|28765213
SCOP:  4003583|4002243

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
232-256 2.65e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 2.65e-05
                          10        20
                  ....*....|....*....|....*
gi 2077863211 232 LKLHIRTHSGEKPYKCKECGKAFTH 256
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 213-291 5.55e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 5.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 213 GEKPYVCK--ECGKAFTQSTGLKLHiRTHSGEKPykckecgkaFTHSSYLTDHTRIHSGK-KPYVCMECGKAFTRSTGLI 289
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQ---------KLHENPSPEKMNIFSAKdKPYRCEVCDKRYKNLNGLK 415


                  ..
gi 2077863211 290 LH 291
Cdd:COG5189   416 YH 417
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-240 7.58e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 161 CECKDCWRTFLNQSSLKLHiRSHNgdkhyvckECGKAFSNSSHLIGHGRIHSGEKPYVCKECGKAFTQSTGLKLHiRTHS 240
Cdd:COG5189   352 CPVEGCNKKYKNQNGLKYH-MLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
KRAB super family cl42959
krueppel associated box;
1-30 6.77e-04

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 37.19  E-value: 6.77e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 2077863211    1 MLENYKNLIILGSELFKRSLMSGLEQMEEL 30
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEP 59
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
232-256 2.65e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 2.65e-05
                          10        20
                  ....*....|....*....|....*
gi 2077863211 232 LKLHIRTHSGEKPYKCKECGKAFTH 256
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 213-291 5.55e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 5.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 213 GEKPYVCK--ECGKAFTQSTGLKLHiRTHSGEKPykckecgkaFTHSSYLTDHTRIHSGK-KPYVCMECGKAFTRSTGLI 289
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQ---------KLHENPSPEKMNIFSAKdKPYRCEVCDKRYKNLNGLK 415


                  ..
gi 2077863211 290 LH 291
Cdd:COG5189   416 YH 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-240 7.58e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 161 CECKDCWRTFLNQSSLKLHiRSHNgdkhyvckECGKAFSNSSHLIGHGRIHSGEKPYVCKECGKAFTQSTGLKLHiRTHS 240
Cdd:COG5189   352 CPVEGCNKKYKNQNGLKYH-MLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
PHA00733 PHA00733
hypothetical protein
 216-263 3.36e-04

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.86  E-value: 3.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2077863211 216 PYVCKECGKAFTQSTGLKLHIRThsGEKPYKCKECGKAFTHSSYLTDH 263
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRY--TEHSKVCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
259-284 6.54e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 6.54e-04
                          10        20
                  ....*....|....*....|....*.
gi 2077863211 259 YLTDHTRIHSGKKPYVCMECGKAFTR 284
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
KRAB smart00349
krueppel associated box;
1-30 6.77e-04

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 37.19  E-value: 6.77e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 2077863211    1 MLENYKNLIILGSELFKRSLMSGLEQMEEL 30
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEP 59
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
75-296 1.99e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.68  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211  75 KLYDSNHSGKVFNEHPFLMTHMITHIGEKTSEDNQSgkalRKNFPHSFYKKSHAEGKMPKCVKHEKAFNQFPNLTRQNKT 154
Cdd:COG5048   210 SIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSP----SSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKG 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 155 HTqeKLCECKDCWRTFLNQSSLKLHIRSHN----GDKHYVCKE--CGKAFSNSSHLIGHGRIHSGEKPYVCK--ECGKAF 226
Cdd:COG5048   286 FS--LPIKSKQCNISFSRSSPLTRHLRSVNhsgeSLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF 363

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2077863211 227 TQSTGLKLH--IRTHSGEKPYKCKE-----CGKAFTHSSYLTDHTRIHSGKKPYVCM--ECGKAFTRSTGLILHMRIHT 296
Cdd:COG5048   364 SPLLNNEPPqsLQQYKDLKNDKKSEtlsnsCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT 442
zf-H2C2_2 pfam13465
Zinc-finger double domain;
175-200 2.72e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 2.72e-03
                          10        20
                  ....*....|....*....|....*.
gi 2077863211 175 SLKLHIRSHNGDKHYVCKECGKAFSN 200
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
232-256 2.65e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 2.65e-05
                          10        20
                  ....*....|....*....|....*
gi 2077863211 232 LKLHIRTHSGEKPYKCKECGKAFTH 256
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 213-291 5.55e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 5.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 213 GEKPYVCK--ECGKAFTQSTGLKLHiRTHSGEKPykckecgkaFTHSSYLTDHTRIHSGK-KPYVCMECGKAFTRSTGLI 289
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQ---------KLHENPSPEKMNIFSAKdKPYRCEVCDKRYKNLNGLK 415


                  ..
gi 2077863211 290 LH 291
Cdd:COG5189   416 YH 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-240 7.58e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 161 CECKDCWRTFLNQSSLKLHiRSHNgdkhyvckECGKAFSNSSHLIGHGRIHSGEKPYVCKECGKAFTQSTGLKLHiRTHS 240
Cdd:COG5189   352 CPVEGCNKKYKNQNGLKYH-MLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
PHA00733 PHA00733
hypothetical protein
 216-263 3.36e-04

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.86  E-value: 3.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2077863211 216 PYVCKECGKAFTQSTGLKLHIRThsGEKPYKCKECGKAFTHSSYLTDH 263
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRY--TEHSKVCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
259-284 6.54e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 6.54e-04
                          10        20
                  ....*....|....*....|....*.
gi 2077863211 259 YLTDHTRIHSGKKPYVCMECGKAFTR 284
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
KRAB smart00349
krueppel associated box;
1-30 6.77e-04

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 37.19  E-value: 6.77e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 2077863211    1 MLENYKNLIILGSELFKRSLMSGLEQMEEL 30
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEP 59
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 245-267 1.26e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.74  E-value: 1.26e-03
                          10        20
                  ....*....|....*....|...
gi 2077863211 245 YKCKECGKAFTHSSYLTDHTRIH 267
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
75-296 1.99e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.68  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211  75 KLYDSNHSGKVFNEHPFLMTHMITHIGEKTSEDNQSgkalRKNFPHSFYKKSHAEGKMPKCVKHEKAFNQFPNLTRQNKT 154
Cdd:COG5048   210 SIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSP----SSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKG 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 155 HTqeKLCECKDCWRTFLNQSSLKLHIRSHN----GDKHYVCKE--CGKAFSNSSHLIGHGRIHSGEKPYVCK--ECGKAF 226
Cdd:COG5048   286 FS--LPIKSKQCNISFSRSSPLTRHLRSVNhsgeSLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKF 363

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2077863211 227 TQSTGLKLH--IRTHSGEKPYKCKE-----CGKAFTHSSYLTDHTRIHSGKKPYVCM--ECGKAFTRSTGLILHMRIHT 296
Cdd:COG5048   364 SPLLNNEPPqsLQQYKDLKNDKKSEtlsnsCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT 442
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 217-239 2.21e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 2.21e-03
                          10        20
                  ....*....|....*....|...
gi 2077863211 217 YVCKECGKAFTQSTGLKLHIRTH 239
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
175-200 2.72e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 2.72e-03
                          10        20
                  ....*....|....*....|....*.
gi 2077863211 175 SLKLHIRSHNGDKHYVCKECGKAFSN 200
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
243-302 3.01e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 38.91  E-value: 3.01e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2077863211 243 KPYKCKECGKAFTHSSYLTDHTRIHSGKKPYVCMECGKAFTRSTGLIL--HMRIHTGEKPYE 302
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELsrHLRTHHNNPSDL 93
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
171-237 4.99e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 38.14  E-value: 4.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2077863211 171 LNQSSLKLHIRSHNGDKHYVCKECGKAFSNSSHLIGHGRIHSGEKPYVCKECGKAFTQSTGLKLHIR 237
Cdd:COG5048    16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRH 82
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
173-301 7.23e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 37.75  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2077863211 173 QSSLKLHIRSHNGDKHYVCkecgkafSNSSHLIGHGRIHSGEKPYVCKECGKAFTQSTGLKLHIRTHSG-EKPYKCKECG 251
Cdd:COG5048   224 SSSLPLTTNSQLSPKSLLS-------QSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCN 296

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2077863211 252 KAFTHSSYLTDHTR--IHSGK--KPYVCME--CGKAFTRSTGLILHMRIHTGEKPY 301
Cdd:COG5048   297 ISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPA 352
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 189-211 8.15e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 33.43  E-value: 8.15e-03
                          10        20
                  ....*....|....*....|...
gi 2077863211 189 YVCKECGKAFSNSSHLIGHGRIH 211
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 273-295 9.16e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 33.04  E-value: 9.16e-03
                          10        20
                  ....*....|....*....|...
gi 2077863211 273 YVCMECGKAFTRSTGLILHMRIH 295
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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