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myocyte-specific enhancer factor 2A isoform 2 [Homo sapiens]
MEF2 family transcription factor( domain architecture ID 13416711)
MEF2 family transcription factor is a MADS (MCM1, Agamous, Deficiens, and SRF)-box transcription factor, similar to human myocyte-specific enhancer factor 2C, a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes
List of domain hits
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Name | Accession | Description | Interval | E-value | |||||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 1.38e-39 | |||||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. : Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 1.38e-39
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ARG80 super family | cl34888 | Regulator of arginine metabolism and related MADS box-containing transcription factors ... |
1-235 | 2.57e-10 | |||||
Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]; The actual alignment was detected with superfamily member COG5068: Pssm-ID: 227400 [Multi-domain] Cd Length: 412 Bit Score: 62.34 E-value: 2.57e-10
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Name | Accession | Description | Interval | E-value | |||||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 1.38e-39 | |||||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 1.38e-39
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MADS | smart00432 | MADS domain; |
2-60 | 3.13e-32 | |||||
MADS domain; Pssm-ID: 197721 [Multi-domain] Cd Length: 59 Bit Score: 117.27 E-value: 3.13e-32
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SRF-TF | pfam00319 | SRF-type transcription factor (DNA-binding and dimerization domain); |
10-57 | 2.10e-24 | |||||
SRF-type transcription factor (DNA-binding and dimerization domain); Pssm-ID: 459760 [Multi-domain] Cd Length: 48 Bit Score: 95.57 E-value: 2.10e-24
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ARG80 | COG5068 | Regulator of arginine metabolism and related MADS box-containing transcription factors ... |
1-235 | 2.57e-10 | |||||
Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]; Pssm-ID: 227400 [Multi-domain] Cd Length: 412 Bit Score: 62.34 E-value: 2.57e-10
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HJURP_C | pfam12347 | Holliday junction regulator protein family C-terminal repeat; Although this family is ... |
97-152 | 7.49e-05 | |||||
Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes. Pssm-ID: 463543 Cd Length: 63 Bit Score: 40.79 E-value: 7.49e-05
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Name | Accession | Description | Interval | E-value | |||||
MADS_MEF2_like | cd00265 | MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ... |
2-78 | 1.38e-39 | |||||
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238165 [Multi-domain] Cd Length: 77 Bit Score: 137.68 E-value: 1.38e-39
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MADS | smart00432 | MADS domain; |
2-60 | 3.13e-32 | |||||
MADS domain; Pssm-ID: 197721 [Multi-domain] Cd Length: 59 Bit Score: 117.27 E-value: 3.13e-32
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MADS | cd00120 | MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ... |
2-60 | 1.90e-29 | |||||
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238067 [Multi-domain] Cd Length: 59 Bit Score: 109.53 E-value: 1.90e-29
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MADS_SRF_like | cd00266 | SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ... |
2-83 | 2.90e-26 | |||||
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi. Pssm-ID: 238166 [Multi-domain] Cd Length: 83 Bit Score: 101.57 E-value: 2.90e-26
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SRF-TF | pfam00319 | SRF-type transcription factor (DNA-binding and dimerization domain); |
10-57 | 2.10e-24 | |||||
SRF-type transcription factor (DNA-binding and dimerization domain); Pssm-ID: 459760 [Multi-domain] Cd Length: 48 Bit Score: 95.57 E-value: 2.10e-24
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ARG80 | COG5068 | Regulator of arginine metabolism and related MADS box-containing transcription factors ... |
1-235 | 2.57e-10 | |||||
Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]; Pssm-ID: 227400 [Multi-domain] Cd Length: 412 Bit Score: 62.34 E-value: 2.57e-10
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HJURP_C | pfam12347 | Holliday junction regulator protein family C-terminal repeat; Although this family is ... |
97-152 | 7.49e-05 | |||||
Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes. Pssm-ID: 463543 Cd Length: 63 Bit Score: 40.79 E-value: 7.49e-05
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Blast search parameters | ||||
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