|
Name |
Accession |
Description |
Interval |
E-value |
| Spectrin_like |
pfam18373 |
Spectrin like domain; Desmoplakin (DP) is an integral part of desmosomes, where it links ... |
651-728 |
6.30e-34 |
|
Spectrin like domain; Desmoplakin (DP) is an integral part of desmosomes, where it links desmosomal cadherins to the intermediate filaments. The N-terminal region of DP contains a plakin domain common to members of the plakin family. Plakin domains contain multiple copies of spectrin repeats (SRs) pfam00435. Spectrin repeats (SRs) consist of three alpha-helices (A, B, and C) that form an antiparallel triple-helical bundle. This entry describes SR6 which has a divergent structure relative to the other SRs. SR6 shows significant deviations in helices A and B where they are significantly shorter than in other repeats. Structural comparison revealed that SR6 is more similar to other three-helix-bundle proteins, including target of Myb1 and the syntaxin Habc domain, than to other SR proteins. Due to these differences with other spectrin repeats, this region is termed spectrin-like repeat.
Pssm-ID: 465730 Cd Length: 78 Bit Score: 125.79 E-value: 6.30e-34
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502443 651 VSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKS 728
Cdd:pfam18373 1 VSWQYLLKDIQRINSWTISMLKTMRPEEYRQVLKNLETHYQDFLRDSQESEMFGAEDRRQLEREVNSAQQHYQTLLVS 78
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1124-1868 |
4.10e-25 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 115.15 E-value: 4.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1124 QRQKATVLEN-SKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELET 1202
Cdd:TIGR02168 178 ERKLERTRENlDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1203 IVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEEntftrrtLEDHLKRKDLSLNDLEQQKNKL---MEELRR 1279
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR-------LEQQKQILRERLANLERQLEELeaqLEELES 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1280 KRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEiqytCRENalpvcpITQATSCRAVTGLQQEHDKQ 1359
Cdd:TIGR02168 331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE----LEEQ------LETLRSKVAQLELQIASLNN 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1360 KAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEekarllkdkLDETNNTLRCLKLELERKDQAEKGYSQQLR 1439
Cdd:TIGR02168 401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE---------LEELEEELEELQEELERLEEALEELREELE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1440 ELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEK-------GKLQREVDRI-------TRAHAVAEKNIQHLN 1505
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqsglsGILGVLSELIsvdegyeAAIEAALGGRLQAVV 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1506 S-------QIHSFRDEKELERLQICQrKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKS------------- 1565
Cdd:TIGR02168 552 VenlnaakKAIAFLKQNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvdd 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1566 -NECAEMLKQKVEE----------------LTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRST 1628
Cdd:TIGR02168 631 lDNALELAKKLRPGyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1629 NEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQ 1708
Cdd:TIGR02168 711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1709 VQ--------------ELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISG 1774
Cdd:TIGR02168 791 IEqlkeelkalrealdELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1775 IRLDFVSLQQENSRAQENAKLCETN-------IKELERQLQQYREQMQQGQHMEANHYQKCQKLE---DELIAQKRE--- 1841
Cdd:TIGR02168 871 LESELEALLNERASLEEALALLRSEleelseeLRELESKRSELRRELEELREKLAQLELRLEGLEvriDNLQERLSEeys 950
|
810 820 830
....*....|....*....|....*....|..
gi 4502443 1842 -----VENLKQKMDQQIKEHEHQLVLLQCEIQ 1868
Cdd:TIGR02168 951 ltleeAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SH3_10 |
pfam17902 |
SH3 domain; This entry represents an SH3 domain. |
550-616 |
5.19e-21 |
|
SH3 domain; This entry represents an SH3 domain.
Pssm-ID: 407754 Cd Length: 65 Bit Score: 88.47 E-value: 5.19e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 550 QLKPRNSdcPLKTSIPIKAICDYRQIEITIYKDDECVLANNSHRAKWKVISPTGNEAMVPSVCFTVP 616
Cdd:pfam17902 1 PLKQRRS--PVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1092-1845 |
5.04e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 98.22 E-value: 5.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1092 IKFAGDSLKRLEEE-----EIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEEL----- 1161
Cdd:TIGR02169 193 IDEKRQQLERLRRErekaeRYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLeeieq 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1162 ------PKVREAAENE--------------LRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLT 1221
Cdd:TIGR02169 273 lleelnKKIKDLGEEEqlrvkekigeleaeIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1222 IEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAfq 1301
Cdd:TIGR02169 353 DKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA-- 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1302 kqVAEKQLKEKQKIELEARRKITEIQytcrenalpvcpitqatscravtglqqehdkQKAEELKQQVDeltaanrKAEQD 1381
Cdd:TIGR02169 431 --GIEAKINELEEEKEDKALEIKKQE-------------------------------WKLEQLAADLS-------KYEQE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1382 MRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGR---------------QLN 1446
Cdd:TIGR02169 471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvgeryataievaagnRLN 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1447 QTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKlQREVDRITRAHAVA------EKNIQHLNSQIHSFRDEKELERL 1520
Cdd:TIGR02169 551 NVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDGVIGfavdlvEFDPKYEPAFKYVFGDTLVVEDI 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1521 QICQRKSDHLK------EQFEKS------HEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKL 1588
Cdd:TIGR02169 630 EAARRLMGKYRmvtlegELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1589 MMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCD 1668
Cdd:TIGR02169 710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1669 QQniiiqntkkEVRNLNAELNASKEEKRRgeqkvqlQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFK 1748
Cdd:TIGR02169 790 HS---------RIPEIQAELSKLEEEVSR-------IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1749 QSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKC 1828
Cdd:TIGR02169 854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
|
810
....*....|....*..
gi 4502443 1829 QKLEDELIAQKREVENL 1845
Cdd:TIGR02169 934 SEIEDPKGEDEEIPEEE 950
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1072-1763 |
2.55e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 95.89 E-value: 2.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1072 QEFMDLRTRYTAL-VTLMTQYIKFAGDSLKRLEEEEIK---RCKET---------------SEHGAYSDLLQRQKATVLE 1132
Cdd:TIGR02168 213 ERYKELKAELRELeLALLVLRLEELREELEELQEELKEaeeELEELtaelqeleekleelrLEVSELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1133 nskLTGKISELERMVAELKKQKSRVEEELpkvrEAAENELRKQQRnvedislQKIRAESEAKQYRRELETIVREKEAAER 1212
Cdd:TIGR02168 293 ---LANEISRLEQQKQILRERLANLERQL----EELEAQLEELES-------KLDELAEELAELEEKLEELKEELESLEA 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1213 ELERVRQLTIEAEAKRAAVEENLLNFR-------NQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNE- 1284
Cdd:TIGR02168 359 ELEELEAELEELESRLEELEEQLETLRskvaqleLQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEl 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1285 --------EELLKLIKQMEkDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCR------------------------- 1331
Cdd:TIGR02168 439 qaeleeleEELEELQEELE-RLEEALEELREELEEAEQALDAAERELAQLQARLDslerlqenlegfsegvkallknqsg 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1332 ----------------------ENALP-----VCPITQATSCRAVTGLQQeHDKQKAE--ELKQQVDELTAANRkAEQDM 1382
Cdd:TIGR02168 518 lsgilgvlselisvdegyeaaiEAALGgrlqaVVVENLNAAKKAIAFLKQ-NELGRVTflPLDSIKGTEIQGND-REILK 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1383 RELTYELNALQLEKTSSE----------------------EKARLLKDKL--------------------DETNNTLRCL 1420
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKlrkalsyllggvlvvddldnalELAKKLRPGYrivtldgdlvrpggvitggsAKTNSSILER 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1421 KLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKN 1500
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1501 IQHLNSQIHSFRD--EKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEE 1578
Cdd:TIGR02168 756 LTELEAEIEELEErlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1579 LTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLH-------KQTKTEQDFQRKIKCLEE 1651
Cdd:TIGR02168 836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrseleELSEELRELESKRSELRR 915
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1652 DLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNL-NAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVqDELHLKTIEE 1730
Cdd:TIGR02168 916 ELEELREKLAQLELRLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL-GPVNLAAIEE 994
|
810 820 830
....*....|....*....|....*....|....*....
gi 4502443 1731 qmthrkmvlFQEESGKF------KQSAEEFRKKMEKLME 1763
Cdd:TIGR02168 995 ---------YEELKERYdfltaqKEDLTEAKETLEEAIE 1024
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
375-557 |
2.56e-19 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 89.04 E-value: 2.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 375 LHNFVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYR 454
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 455 AAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQrkySCDRSSSIHKLEDLVQESMEEKEELLQY 534
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA---SEDLGKDLESVEELLKKHKELEEELEAH 158
|
170 180
....*....|....*....|...
gi 4502443 535 KSTIANLMGKAKTIIQLKPRNSD 557
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDAD 181
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1097-1800 |
3.07e-19 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 95.98 E-value: 3.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1097 DSLKRLEE----EEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENEL 1172
Cdd:PTZ00121 1125 EDARKAEEarkaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEA 1204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1173 RKQQRNVEDIS-LQKIRAESEAKQYRRELETIVREKEAAERELER-----------------VRQLTIEAEAKRAAVEEN 1234
Cdd:PTZ00121 1205 ARKAEEERKAEeARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERnneeirkfeearmahfaRRQAAIKAEEARKADELK 1284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1235 LLNFRNQLEEntfTRRTLE----DHLKRKDLSLNDLEQQKNKLME------ELRRKRDNEEELLKLIKQMEKDLAFQKQV 1304
Cdd:PTZ00121 1285 KAEEKKKADE---AKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEakkkadAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1305 AEKQLKEKQKIELEARRKITEIQYTCRENAlpvcpitqatscravtglQQEHDKQKAEELKQQVDEL---TAANRKAEQD 1381
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKK------------------KADEAKKKAEEDKKKADELkkaAAAKKKADEA 1423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1382 MRELTYELNALQLEKTSSE-EKARLLKDKLDETNntlrclKLELERKDQAEKGYSQQLR---ELGRQLNQTTGKAEEAMQ 1457
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKKAEEaKKADEAKKKAEEAK------KAEEAKKKAEEAKKADEAKkkaEEAKKADEAKKKAEEAKK 1497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1458 EASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKEL----------------ERLQ 1521
Cdd:PTZ00121 1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaeeakkaeEDKN 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1522 ICQRKSDHLKEQFEKSHEQLLQNIKAEKENN-DKIQRLNEELEKSNEC--AEMLKQKVEELTRQNNETKLMMQRIQAESE 1598
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKaEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1599 NIVLEKQTIQQRCEALKIQAdgfkDQLRSTNEHLHK---QTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQ 1675
Cdd:PTZ00121 1658 ENKIKAAEEAKKAEEDKKKA----EEAKKAEEDEKKaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1676 NTKKEvrnlnaelnaSKEEKRRGEQ--KVQLQQAQVQELNNRLKKVQDELHLK---TIEEQMTHRKMVLFQEESGKFKQS 1750
Cdd:PTZ00121 1734 EAKKE----------AEEDKKKAEEakKDEEEKKKIAHLKKEEEKKAEEIRKEkeaVIEEELDEEDEKRRMEVDKKIKDI 1803
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 4502443 1751 AEEFRKKMEKLMESKVIT----ENDISGIR--LDFVSLQQENSRAQENAKLCETNI 1800
Cdd:PTZ00121 1804 FDNFANIIEGGKEGNLVIndskEMEDSAIKevADSKNMQLEEADAFEKHKFNKNNE 1859
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1194-1875 |
2.93e-18 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 92.43 E-value: 2.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1194 KQYRRELEtivREKEAAERELERV--------RQL-TIEAEAKRAaveENLLNFRNQLEEntftrrtledhlKRKDLSLN 1264
Cdd:TIGR02168 171 KERRKETE---RKLERTRENLDRLedilneleRQLkSLERQAEKA---ERYKELKAELRE------------LELALLVL 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1265 DLEqqknklmeELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQat 1344
Cdd:TIGR02168 233 RLE--------ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ-- 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1345 scravtglQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLEL 1424
Cdd:TIGR02168 303 --------QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1425 ERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLN-----HEKGKLQREVDRITRAHAVAEK 1499
Cdd:TIGR02168 375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLkkleeAELKELQAELEELEEELEELQE 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1500 NIQHLNSQIHSFRDEKELERLQICQRKSDH------------LKEQFEKSHEQLLQNIKAEKENNDKIQRL------NEE 1561
Cdd:TIGR02168 455 ELERLEEALEELREELEEAEQALDAAERELaqlqarldslerLQENLEGFSEGVKALLKNQSGLSGILGVLselisvDEG 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1562 LEKSNECA-------------EMLKQKVEELtRQNNETKLMM--------QRIQAESENIVLEKQTIQQRCEALKIQADG 1620
Cdd:TIGR02168 535 YEAAIEAAlggrlqavvvenlNAAKKAIAFL-KQNELGRVTFlpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1621 FK-------------DQLRSTNEhLHKQTKTEQDF----------------------------QRKIKCLEEDLAKSQNL 1659
Cdd:TIGR02168 614 LRkalsyllggvlvvDDLDNALE-LAKKLRPGYRIvtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEEK 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1660 VSEFKQKCDQQNIIIQNTKKEVRNLNAE-------LNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQM 1732
Cdd:TIGR02168 693 IAELEKALAELRKELEELEEELEQLRKEleelsrqISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1733 THRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYRE 1812
Cdd:TIGR02168 773 AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4502443 1813 QMQQGQH-MEanhyqKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAKD 1875
Cdd:TIGR02168 853 DIESLAAeIE-----ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1107-1857 |
3.79e-18 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 92.51 E-value: 3.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1107 IKRCKETSEHGAYSDLLQRQ-----------------KATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAE 1169
Cdd:PTZ00121 1026 IEKIEELTEYGNNDDVLKEKdiidedidgnhegkaeaKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKK 1105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1170 NELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTR 1249
Cdd:PTZ00121 1106 TETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE 1185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1250 RTLEDHLKRKDLSLNDLEQQKN----KLMEELRRKRDNEE-ELLKLIKQMEKDlafqKQVAEKQLKEKQKIELEARRKIT 1324
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKaeeeRKAEEARKAEDAKKaEAVKKAEEAKKD----AEEAKKAEEERNNEEIRKFEEAR 1261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1325 EIQYTCRENALpvcpitQATSCRAVTGLQQEHDKQKAEELK--QQVDELTAANRKAEQDMReltyelnALQLEKTSSE-- 1400
Cdd:PTZ00121 1262 MAHFARRQAAI------KAEEARKADELKKAEEKKKADEAKkaEEKKKADEAKKKAEEAKK-------ADEAKKKAEEak 1328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1401 EKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKrnyqlELESLNHEK 1480
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-----EAKKKAEED 1403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1481 GKLQREVDRitraHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKA-EKENNDKIQRLN 1559
Cdd:PTZ00121 1404 KKKADELKK----AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAeEAKKADEAKKKA 1479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1560 EELEKSNEC---AEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRC---EALKIQADGFKDQLRSTNEHLH 1633
Cdd:PTZ00121 1480 EEAKKADEAkkkAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKkadEAKKAEEKKKADELKKAEELKK 1559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1634 KQTKTEQDFQRKikcLEEDLAKSQNLVSEFKQkcdqqniIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELN 1713
Cdd:PTZ00121 1560 AEEKKKAEEAKK---AEEDKNMALRKAEEAKK-------AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1714 NRLKKVqdELHLKTIEEQMTHRKMVLFQEESGKFKqsAEEFRKKMEklmeskvitendisgirldfvslqqENSRAQENA 1793
Cdd:PTZ00121 1630 EEKKKV--EQLKKKEAEEKKKAEELKKAEEENKIK--AAEEAKKAE-------------------------EDKKKAEEA 1680
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1794 KLCETNIKELERQLQQYREQMQQGQHM---EANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHE 1857
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELkkkEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE 1747
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1135-1493 |
2.79e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 89.35 E-value: 2.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1135 KLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVR---EKEAAE 1211
Cdd:TIGR02168 688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEleaEIEELE 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1212 RELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLI 1291
Cdd:TIGR02168 768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1292 KQMEKDLAFqkqvAEKQLKEKQKIELEARRKITEiqytcrenalpvcpitqATSCRAVTGLQQEHDKQKAEELKQQVDEL 1371
Cdd:TIGR02168 848 EELSEDIES----LAAEIEELEELIEELESELEA-----------------LLNERASLEEALALLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1372 TAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQ-QLRELGRQLNQTTG 1450
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGP 986
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 4502443 1451 KAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQ---REVDRITRA 1493
Cdd:TIGR02168 987 VNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEeaiEEIDREARE 1032
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1234-1875 |
9.06e-17 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 87.00 E-value: 9.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1234 NLLNFRNQLEENTFTR-RTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEK 1312
Cdd:TIGR04523 26 NIANKQDTEEKQLEKKlKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1313 QKIELEARRKITEIqytcrenalpvcpitqatscravtgLQQEHDKQKAEELKQQVDELTAAN----RKAEQDMRELTYE 1388
Cdd:TIGR04523 106 SKINSEIKNDKEQK-------------------------NKLEVELNKLEKQKKENKKNIDKFlteiKKKEKELEKLNNK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1389 LNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLE----------LERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQE 1458
Cdd:TIGR04523 161 YNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKllklelllsnLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1459 ASDLKKIKRNYQLEL----ESLNHEKGKL---QREVDRITRAHAVAEKNIQHLNSQIHSFRDEKElerlqicQRKSDHLK 1531
Cdd:TIGR04523 241 INEKTTEISNTQTQLnqlkDEQNKIKKQLsekQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE-------QDWNKELK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1532 EQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKsnecaemLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRC 1611
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQ-------LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEI 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1612 EALKIQADGFKDQLRstnehlhKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNAS 1691
Cdd:TIGR04523 387 KNLESQINDLESKIQ-------NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNL 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1692 KEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITEND 1771
Cdd:TIGR04523 460 DNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1772 ISGIRLDFVSLQQENSRaqenaklceTNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQ 1851
Cdd:TIGR04523 540 ISDLEDELNKDDFELKK---------ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK 610
|
650 660
....*....|....*....|....
gi 4502443 1852 QIKEHEHQLVLLQCEIQKKSTAKD 1875
Cdd:TIGR04523 611 KISSLEKELEKAKKENEKLSSIIK 634
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1140-1718 |
9.26e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 87.30 E-value: 9.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1140 ISELERMVAELKKQKSR------VEEELpKVREAAE--NELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAE 1211
Cdd:COG1196 195 LGELERQLEPLERQAEKaeryreLKEEL-KELEAELllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1212 RELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLI 1291
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1292 KQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQytcrenalpvcpitQATSCRAVTGLQQEHDKQKAEELKQQVDEL 1371
Cdd:COG1196 354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELL--------------EALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1372 TAANRKAEQDMREltyELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGK 1451
Cdd:COG1196 420 EEELEELEEALAE---LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1452 AEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERL----------- 1520
Cdd:COG1196 497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYlkaakagratf 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1521 ----QICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSN---ECAEMLKQKVEELTRQNNETKLMMQRI 1593
Cdd:COG1196 577 lpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTlvaARLEAALRRAVTLAGRLREVTLEGEGG 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1594 QAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQkcdQQNII 1673
Cdd:COG1196 657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE---QLEAE 733
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 4502443 1674 IQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKK 1718
Cdd:COG1196 734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
282-477 |
9.54e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 81.34 E-value: 9.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 282 VQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISE---IQMTAPLKLTYAEKLHRLESQY 358
Cdd:cd00176 9 ADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGeqlIEEGHPDAEEIQERLEELNQRW 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 359 AKLLNTSRNQERHLDT---LHNFVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEI 435
Cdd:cd00176 89 EELRELAEERRQRLEEaldLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELEEELEAHEPRLKSLNEL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 4502443 436 AEQLLLENHP-ARLTIEAYRAAMQTQWSWILQLCQCVEQHIKE 477
Cdd:cd00176 169 AEELLEEGHPdADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
912-1870 |
1.74e-16 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 86.64 E-value: 1.74e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 912 KAKAISDEMFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQ 991
Cdd:TIGR00606 186 KALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIM 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 992 ENQPENSKTLATQLNQQKmLVSEIEMKQSKM-----DECQKYAEQYSATVKDYElqtmtyRAMVDSQQKSpvkrRRMQSS 1066
Cdd:TIGR00606 266 KLDNEIKALKSRKKQMEK-DNSELELKMEKVfqgtdEQLNDLYHNHQRTVREKE------RELVDCQREL----EKLNKE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1067 ADLIIQEFMDLRTR--YTALVTLMTQYIKFAGDSLKrlEEEEIKRCKETSEHGAYSDLlQRQKATVLENSKLTGKISELE 1144
Cdd:TIGR00606 335 RRLLNQEKTELLVEqgRLQLQADRHQEHIRARDSLI--QSLATRLELDGFERGPFSER-QIKNFHTLVIERQEDEAKTAA 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1145 RMVAELKKQKSRVEEELPKVREaaenELRKQQRNVEDISLQKIRAESEAKQYRRELETIvrekEAAERELERVRQLTIEA 1224
Cdd:TIGR00606 412 QLCADLQSKERLKQEQADEIRD----EKKGLGRTIELKKEILEKKQEELKFVIKELQQL----EGSSDRILELDQELRKA 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1225 EAKRAAVEENllnfrnqleENTFTRRTLEDHLKRKDLslnDLEQQKNKLMEELRRKRDNEEELlkliKQMEkdlafqkQV 1304
Cdd:TIGR00606 484 ERELSKAEKN---------SLTETLKKEVKSLQNEKA---DLDRKLRKLDQEMEQLNHHTTTR----TQME-------ML 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1305 AEKQLKEKQKIelearRKITEIQYTCRENALPVCPITQATScravtglQQEHDKQKaeELKQQVDELTAANR---KAEQD 1381
Cdd:TIGR00606 541 TKDKMDKDEQI-----RKIKSRHSDELTSLLGYFPNKKQLE-------DWLHSKSK--EINQTRDRLAKLNKelaSLEQN 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1382 MRELTYELNALQLEKTSSEEK------ARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQ------LNQTT 1449
Cdd:TIGR00606 607 KNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDEnqsccpVCQRV 686
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1450 GKAEEAMQE-ASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRdekelERLQICQRKSD 1528
Cdd:TIGR00606 687 FQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR-----NKLQKVNRDIQ 761
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1529 HLKEQFEKsHEQLLQNIKAEKENNDK-------IQRLNEELEKSNECAEMLKQKVE--ELTRQNNETKLMMQRIQAESEN 1599
Cdd:TIGR00606 762 RLKNDIEE-QETLLGTIMPEEESAKVcltdvtiMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDT 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1600 IVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKK 1679
Cdd:TIGR00606 841 VVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEK 920
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1680 EVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQdelhlKTIEEQMTHRKMVLfQEESGKFKQSAEEFRKKME 1759
Cdd:TIGR00606 921 DQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIE-----NKIQDGKDDYLKQK-ETELNTVNAQLEECEKHQE 994
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1760 KLmeskvitENDISGIRLDFVSLQQENSRAQENAKL--CETNIKELERQLQQYREQMQQGQHMEANhyQKCQKLEDELia 1837
Cdd:TIGR00606 995 KI-------NEDMRLMRQDIDTQKIQERWLQDNLTLrkRENELKEVEEELKQHLKEMGQMQVLQMK--QEHQKLEENI-- 1063
|
970 980 990
....*....|....*....|....*....|...
gi 4502443 1838 qkREVENLKQKMDQQIKEHEHQLVLLQCEIQKK 1870
Cdd:TIGR00606 1064 --DLIKRNHVLALGRQKGYEKEIKHFKKELREP 1094
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
935-1721 |
7.21e-16 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 84.78 E-value: 7.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 935 KEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYY-RDTYHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQKMLVS 1013
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYlRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1014 EIE----MKQSKMDECQKYAEQYSATVKDYELQTMTYRA-MVDSQQKSPVKRRRMQSSADLiiqEFMDLRTRYTALVTLM 1088
Cdd:pfam15921 153 ELEaakcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSiLVDFEEASGKKIYEHDSMSTM---HFRSLGSAISKILREL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1089 TQYIKFAGDSLKRLEEEeIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAA 1168
Cdd:pfam15921 230 DTEISYLKGRIFPVEDQ-LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1169 ENELRKQQRNVEDIslqkiraESEAKQYRRELETIVREKEAAERELERvrQLTI------EAEAKRAAVEENLLNFRNQL 1242
Cdd:pfam15921 309 RNQNSMYMRQLSDL-------ESTVSQLRSELREAKRMYEDKIEELEK--QLVLanseltEARTERDQFSQESGNLDDQL 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1243 EentftrRTLED-HLKRKDLSLndlEQQKNKLMEElrRKRDNEEELLKLIKQMEkDLAFQKQVAEKQLKE-KQKIELEAR 1320
Cdd:pfam15921 380 Q------KLLADlHKREKELSL---EKEQNKRLWD--RDTGNSITIDHLRRELD-DRNMEVQRLEALLKAmKSECQGQME 447
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1321 RKITEIQytcrenalpvcpiTQATSCRAVTGLQQEHDKQKaEELKQQVDELTAANRKAEQDMRELTYELNALQ-----LE 1395
Cdd:pfam15921 448 RQMAAIQ-------------GKNESLEKVSSLTAQLESTK-EMLRKVVEELTAKKMTLESSERTVSDLTASLQekeraIE 513
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1396 KTSSE------------EKARLLKDKLDETNNT---LRCLKLELERKDQAEKGYSQQLRELgRQLNQTTGKAEEAMQ-EA 1459
Cdd:pfam15921 514 ATNAEitklrsrvdlklQELQHLKNEGDHLRNVqteCEALKLQMAEKDKVIEILRQQIENM-TQLVGQHGRTAGAMQvEK 592
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1460 SDLKKIKRNYQLELESLNHEKGKlqrevdritrahavAEKNIQHLNSQIHSFrdekELERLQICQRKSDHLK--EQFEKS 1537
Cdd:pfam15921 593 AQLEKEINDRRLELQEFKILKDK--------------KDAKIRELEARVSDL----ELEKVKLVNAGSERLRavKDIKQE 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1538 HEQLLQNIKAEKennDKIQRLNEELE--KSNecaemLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQ-QRCEAL 1614
Cdd:pfam15921 655 RDQLLNEVKTSR---NELNSLSEDYEvlKRN-----FRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgSDGHAM 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1615 KIqADGFKDQLRSTNEHLHKqtkteqdFQRKIKCLEEDLA---KSQNLVSEFKQKCDQQniiIQNTKKEVRNLNAELNAS 1691
Cdd:pfam15921 727 KV-AMGMQKQITAKRGQIDA-------LQSKIQFLEEAMTnanKEKHFLKEEKNKLSQE---LSTVATEKNKMAGELEVL 795
|
810 820 830
....*....|....*....|....*....|
gi 4502443 1692 KEEKRRGEQKVQLQQAQVQELNNRLKKVQD 1721
Cdd:pfam15921 796 RSQERRLKEKVANMEVALDKASLQFAECQD 825
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1165-1860 |
3.23e-15 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 82.71 E-value: 3.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1165 REAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIE---AEAKRAAVEENLLNFRNQ 1241
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDylkLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1242 LEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLK----LIKQMEKDLAFQKQVAEKQLKEKQKIEL 1317
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKsellKLERRKVDDEEKLKESEKEKKKAEKELK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1318 EARRKITEIQytcRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKT 1397
Cdd:pfam02463 332 KEKEEIEELE---KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1398 SSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDL----KKIKRNYQLEL 1473
Cdd:pfam02463 409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLlketQLVKLQEQLEL 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1474 ESL--------------------------NHEKGKLQREVDRITRAHAVAEK-------NIQHLNSQIHSFRDEKELERL 1520
Cdd:pfam02463 489 LLSrqkleersqkeskarsglkvllalikDGVGGRIISAHGRLGDLGVAVENykvaistAVIVEVSATADEVEERQKLVR 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1521 QICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEE-------LEKSNECAEMLKQKVEELTRQNNETKLMMQRI 1593
Cdd:pfam02463 569 ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDkatleadEDDKRAKVVEGILKDTELTKLKESAKAKESGL 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1594 QAESE-----------NIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNlvSE 1662
Cdd:pfam02463 649 RKGVSleeglaeksevKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA--DR 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1663 FKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQK-----VQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737
Cdd:pfam02463 727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEkselsLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1738 VLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRL-DFVSLQQENSRAQEN-AKLCETNIKELERQLQQYREQMQ 1815
Cdd:pfam02463 807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQkLEKLAEEELERLEEEiTKEELLQELLLKEEELEEQKLKD 886
|
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 4502443 1816 QGQHMEANHYQKcQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 1860
Cdd:pfam02463 887 ELESKEEKEKEE-KKELEEESQKLNLLEEKENEIEERIKEEAEIL 930
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1169-1562 |
5.95e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.64 E-value: 5.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1169 ENELRKQQRNVEDISLQKIRAESEAKQYRRELETIvrekeaaERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFT 1248
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEEL-------EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1249 RRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLafqkQVAEKQLKEKQKIELEARRKITEIQY 1328
Cdd:TIGR02168 749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL----KALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1329 TCRenalpvcpitQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKD 1408
Cdd:TIGR02168 825 RLE----------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1409 KLDETNNTLRclklELERKDQAEKGYSQQLRELGRQLNQTTGKAEeaMQEASDLKKIKRNYQLELE-------SLNHEKG 1481
Cdd:TIGR02168 895 ELEELSEELR----ELESKRSELRRELEELREKLAQLELRLEGLE--VRIDNLQERLSEEYSLTLEeaealenKIEDDEE 968
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1482 KLQREVDRITRahavAEKNIQHLN-SQIHSFRDEKElerlqicqRKsDHLKEQFE---KSHEQLLQNIK-----AEKENN 1552
Cdd:TIGR02168 969 EARRRLKRLEN----KIKELGPVNlAAIEEYEELKE--------RY-DFLTAQKEdltEAKETLEEAIEeidreARERFK 1035
|
410
....*....|
gi 4502443 1553 DKIQRLNEEL 1562
Cdd:TIGR02168 1036 DTFDQVNENF 1045
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
762-1583 |
9.39e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 9.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 762 RQIRTPLERDDLHESVFRITEqekLKKELERLKDDLGTITNKCEEFFSQAAAS-SSVPTLRSELNVVlqnmnqvysmsST 840
Cdd:TIGR02168 216 KELKAELRELELALLVLRLEE---LREELEELQEELKEAEEELEELTAELQELeEKLEELRLEVSEL-----------EE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 841 YIDKLKTVNLVLKNTQAaealvKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEM 920
Cdd:TIGR02168 282 EIEELQKELYALANEIS-----RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 921 FKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDD----WIQQVETTQRKIQENQpe 996
Cdd:TIGR02168 357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrrerLQQEIEELLKKLEEAE-- 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 997 nSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMD 1076
Cdd:TIGR02168 435 -LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1077 LRTRYTALVTLMTQYIKFA-----------GDSLKRLEEEEIKRCKETSEHGAYSDLlqrQKATVLENSKLTG-KISELE 1144
Cdd:TIGR02168 514 NQSGLSGILGVLSELISVDegyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNEL---GRVTFLPLDSIKGtEIQGND 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1145 RMVAELKKQKSRVEEELPKVREAAE---NELRKQQRNVEDISlqkiRAESEAKQYRRElETIVrekeAAERELERVRQLT 1221
Cdd:TIGR02168 591 REILKNIEGFLGVAKDLVKFDPKLRkalSYLLGGVLVVDDLD----NALELAKKLRPG-YRIV----TLDGDLVRPGGVI 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1222 IEAEAKRAAveeNLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQ 1301
Cdd:TIGR02168 662 TGGSAKTNS---SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1302 KQVAEKQLKEKQKIELEARRKITEIqytcrenalpvcpiTQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQD 1381
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEI--------------EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1382 MRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLnqttgkaEEAMQEASD 1461
Cdd:TIGR02168 805 LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI-------EELESELEA 877
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1462 LKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRdekelERLQICQRKSDHLKEQFEKSHEQL 1541
Cdd:TIGR02168 878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-----LRLEGLEVRIDNLQERLSEEYSLT 952
|
810 820 830 840
....*....|....*....|....*....|....*....|...
gi 4502443 1542 LQNIKAEKENND-KIQRLNEELEKsnecaemLKQKVEELTRQN 1583
Cdd:TIGR02168 953 LEEAEALENKIEdDEEEARRRLKR-------LENKIKELGPVN 988
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1223-1851 |
1.24e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.28 E-value: 1.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1223 EAEAKRAAVEENLlnfrnqleentfTRrtLEDHLKRKDLSLNDLEQQKNK------LMEELRRkRDNEEELLKLikqmek 1296
Cdd:COG1196 176 EAERKLEATEENL------------ER--LEDILGELERQLEPLERQAEKaeryreLKEELKE-LEAELLLLKL------ 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1297 dlafqkQVAEKQLKEKQKIELEARRKITEIQytcrenalpvcpitqatscravtgLQQEHDKQKAEELKQQVDELTAANR 1376
Cdd:COG1196 235 ------RELEAELEELEAELEELEAELEELE------------------------AELAELEAELEELRLELEELELELE 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1377 KAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDEtnntlrcLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAM 1456
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1457 QEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKE---------LERLQICQRKS 1527
Cdd:COG1196 358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLErleeeleelEEALAELEEEE 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1528 DHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTI 1607
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1608 QQR--CEALKIQADGFK-----DQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLV--SEFKQKCDQQNIIIQNTK 1678
Cdd:COG1196 518 GLRglAGAVAVLIGVEAayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLplDKIRARAALAAALARGAI 597
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1679 KEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNN----RLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEF 1754
Cdd:COG1196 598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEaalrRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1755 RKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDE 1834
Cdd:COG1196 678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757
|
650 660
....*....|....*....|.
gi 4502443 1835 LI----AQKREVENLKQKMDQ 1851
Cdd:COG1196 758 EPpdleELERELERLEREIEA 778
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1179-1849 |
1.39e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 77.08 E-value: 1.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1179 VEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLtieAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKR 1258
Cdd:pfam15921 59 VELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQRRLNESNEL---HEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1259 KDLSLNDLEQQKNKLMEELRRKRDNEEELLK----LIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEiqytcrENA 1334
Cdd:pfam15921 136 ESQSQEDLRNQLQNTVHELEAAKCLKEDMLEdsntQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE------HDS 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1335 LPVCPITQATScrAVTGLQQEHDKQkAEELKQQV----DELTAANRKAEQDMrELTYELNALQLEKTSSEEKARL--LKD 1408
Cdd:pfam15921 210 MSTMHFRSLGS--AISKILRELDTE-ISYLKGRIfpveDQLEALKSESQNKI-ELLLQQHQDRIEQLISEHEVEItgLTE 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1409 KLDETNNTLRCLKLELE-RKDQAEKGYSQQLRELGrQLNQTTGkaeeamQEASDLKKIKRNYQLELESL-------NHEK 1480
Cdd:pfam15921 286 KASSARSQANSIQSQLEiIQEQARNQNSMYMRQLS-DLESTVS------QLRSELREAKRMYEDKIEELekqlvlaNSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1481 GKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQ---ICQRKS------DHLKEQFEKSH------EQLLQNI 1545
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrLWDRDTgnsitiDHLRRELDDRNmevqrlEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1546 KAE-----KENNDKIQRLNEELEKSNECA-------EMLKQKVEELTRQnnetKLMMQRIQAESENIVLEKQTIQQRCEA 1613
Cdd:pfam15921 439 KSEcqgqmERQMAAIQGKNESLEKVSSLTaqlestkEMLRKVVEELTAK----KMTLESSERTVSDLTASLQEKERAIEA 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1614 LKIQADGFKDQLR---STNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKcdqqniiIQNTKKEVRNLNAELNA 1690
Cdd:pfam15921 515 TNAEITKLRSRVDlklQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ-------IENMTQLVGQHGRTAGA 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1691 SKEEKRRGEQKVQLQQAQVQELnnRLKKVQDELHLKTIEEQMTH---RKMVLFQEESGKFKqSAEEFRKKMEKLMESKVI 1767
Cdd:pfam15921 588 MQVEKAQLEKEINDRRLELQEF--KILKDKKDAKIRELEARVSDlelEKVKLVNAGSERLR-AVKDIKQERDQLLNEVKT 664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1768 TENDISGIRLDFVSLQQeNSRAQENAKLCETN-----IKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREV 1842
Cdd:pfam15921 665 SRNELNSLSEDYEVLKR-NFRNKSEEMETTTNklkmqLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI 743
|
....*..
gi 4502443 1843 ENLKQKM 1849
Cdd:pfam15921 744 DALQSKI 750
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1201-2077 |
1.89e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 1.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1201 ETIVREKEAAERELERVRQLTIEAEAKRAAVEENllnfRNQLEENTFTRrtledhlKRKDLSLNDLEQQKNKLMEELRRK 1280
Cdd:PTZ00121 1039 DDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGL----KPSYKDFDFDA-------KEDNRADEATEEAFGKAEEAKKTE 1107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1281 RDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIElEARRKiteiqytcrENALPVCPITQATSCRAVTGLQQEHDKQK 1360
Cdd:PTZ00121 1108 TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAE-EARKA---------EDAKRVEIARKAEDARKAEEARKAEDAKK 1177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1361 AEELKQQVDELTAAN-RKAE-----QDMRELTYELNALQLEKTSSEEKARLLKdKLDETNNTLRCLKLELERKDQAEKGY 1434
Cdd:PTZ00121 1178 AEAARKAEEVRKAEElRKAEdarkaEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 SQQLRELGRQLNQTTGKAEEAmQEASDLKKIKRNYQLELESLNHEKGKLQ---------REVDRITRAHAVAEKNIQHLN 1505
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEA-RKADELKKAEEKKKADEAKKAEEKKKADeakkkaeeaKKADEAKKKAEEAKKKADAAK 1335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1506 SQIHSFRDEKELERLQiCQRKSDHLKEQFEKSHEQLLQNiKAEKENNDKIQRLNEELEKSNEC---AEMLKQKVEELTRQ 1582
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAE-AEAAADEAEAAEEKAEAAEKKK-EEAKKKADAAKKKAEEKKKADEAkkkAEEDKKKADELKKA 1413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1583 NNETKlMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEE----DLAKSQn 1658
Cdd:PTZ00121 1414 AAAKK-KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEakkaDEAKKK- 1491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1659 lVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMV 1738
Cdd:PTZ00121 1492 -AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1739 LFQEESGKFKQSAEEFRKKMEKLMEskvitenDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQlqqyREQMQQGQ 1818
Cdd:PTZ00121 1571 KAEEDKNMALRKAEEAKKAEEARIE-------EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE----KKKVEQLK 1639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1819 HMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHqlvLLQCEIQKKSTAKDCTFKPDFEMTVKECQHSGELSSR 1898
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1899 NTGHLHPTPRSPLLRWTQEPQPLEEkwQHRVVEQIPKEVQFQPPGAPLEKEKSQQCySEYFSQTSTELQITFDETNPITR 1978
Cdd:PTZ00121 1717 KAEELKKAEEENKIKAEEAKKEAEE--DKKKAEEAKKDEEEKKKIAHLKKEEEKKA-EEIRKEKEAVIEEELDEEDEKRR 1793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1979 LSEIEKIRD--------QALNNSRPPvrYQDNACEMElVKVLTPLEIAKNKQYDMHTEVTTLKQEKNPVpSAEEWMLEGC 2050
Cdd:PTZ00121 1794 MEVDKKIKDifdnfaniIEGGKEGNL--VINDSKEME-DSAIKEVADSKNMQLEEADAFEKHKFNKNNE-NGEDGNKEAD 1869
|
890 900
....*....|....*....|....*..
gi 4502443 2051 RASGGLKKGDFLKKGLEPETFQNFDGD 2077
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADEIEKIDKD 1896
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1122-1620 |
3.86e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 3.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1122 LLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELE 1201
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1202 TIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEEntftRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKR 1281
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA----LLEAEAELAEAEEELEELAEELLEALRAAAELA 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1282 DNEEELLKLIKQMEKDLA-FQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALpvcpitqatscravtGLQQEHDKQK 1360
Cdd:COG1196 400 AQLEELEEAEEALLERLErLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL---------------EEEEEALLEL 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1361 AEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRE 1440
Cdd:COG1196 465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1441 LGRQLNQTTGKAEEAMQEASDLK-------------KIKRNYQLELESLNHEKGKLQREVDRITRAHA---------VAE 1498
Cdd:COG1196 545 AAALQNIVVEDDEVAAAAIEYLKaakagratflpldKIRARAALAAALARGAIGAAVDLVASDLREADaryyvlgdtLLG 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1499 KNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEE 1578
Cdd:COG1196 625 RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 4502443 1579 LTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADG 1620
Cdd:COG1196 705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1174-1864 |
3.87e-13 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 75.53 E-value: 3.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1174 KQQRNVEDISLQKIRAESEAKQYRRELEtivREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRrtle 1253
Cdd:pfam05483 82 KLYKEAEKIKKWKVSIEAELKQKENKLQ---ENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATR---- 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1254 dHLkrkdlsLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLafqkqvaEKQLKEKQKIELEARRKITEIQYTCREN 1333
Cdd:pfam05483 155 -HL------CNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-------EKMILAFEELRVQAENARLEMHFKLKED 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1334 AlpvcpitqatscRAVTGLQQEHDKQKAEElKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDET 1413
Cdd:pfam05483 221 H------------EKIQHLEEEYKKEINDK-EKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKEL 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1414 N-------NTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELES--------LNH 1478
Cdd:pfam05483 288 IekkdhltKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEAttcsleelLRT 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1479 EKGKLQREVDRITRAHAVAEKNIQHLnSQIHSFRDEK--ELERLQICQRKSDHL---KEQFEKSHEQlLQNIKAE----- 1548
Cdd:pfam05483 368 EQQRLEKNEDQLKIITMELQKKSSEL-EEMTKFKNNKevELEELKKILAEDEKLldeKKQFEKIAEE-LKGKEQElifll 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1549 KENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIqadgfkdQLRST 1628
Cdd:pfam05483 446 QAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTL-------ELKKH 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1629 NEHLHKQTKTEQDFQRKIKCLEEDLAKSQN----LVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQL 1704
Cdd:pfam05483 519 QEDIINCKKQEERMLKQIENLEEKEMNLRDelesVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNN 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1705 QQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKF-------KQSAEEFRKKMEKLMESKVITENDISG--- 1774
Cdd:pfam05483 599 LKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLelelasaKQKFEEIIDNYQKEIEDKKISEEKLLEeve 678
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1775 ----IRLDFVSLQQE-NSRAQ----ENAKLCETN-------IKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQ 1838
Cdd:pfam05483 679 kakaIADEAVKLQKEiDKRCQhkiaEMVALMEKHkhqydkiIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSL 758
|
730 740
....*....|....*....|....*.
gi 4502443 1839 KREVENLKQKMDQQIKEHEHQLVLLQ 1864
Cdd:pfam05483 759 KKQLEIEKEEKEKLKMEAKENTAILK 784
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
2480-2517 |
3.88e-13 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 65.43 E-value: 3.88e-13
10 20 30
....*....|....*....|....*....|....*...
gi 4502443 2480 LEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFAQQL 2517
Cdd:pfam00681 2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1207-1816 |
4.50e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 4.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1207 KEAAERELERVRQ-LTiEAEAKRAAVEENLlnfrNQLE---ENTFTRRTLEDHLKRKDLSL-----NDLEQQKNKLMEEL 1277
Cdd:COG1196 174 KEEAERKLEATEEnLE-RLEDILGELERQL----EPLErqaEKAERYRELKEELKELEAELlllklRELEAELEELEAEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1278 RRKRDNEEELLKLIKQMEKDLAFQKQV---AEKQLKEKQKIELEARRKITEIQytcrenalpvcpitqatscravtgLQQ 1354
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLEleeLELELEEAQAEEYELLAELARLE------------------------QDI 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1355 EHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGY 1434
Cdd:COG1196 305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 SQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRD- 1513
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEl 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1514 -EKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEmLKQKVEELTRQNNETKLMMQR 1592
Cdd:COG1196 465 lAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL-AGAVAVLIGVEAAYEAALEAA 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1593 IQAESENIVLEKQTIQQRC-EALKIQADGF-------KDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEF- 1663
Cdd:COG1196 544 LAAALQNIVVEDDEVAAAAiEYLKAAKAGRatflpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLl 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1664 -----KQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMV 1738
Cdd:COG1196 624 grtlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502443 1739 LFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFvslQQENSRAQENAKLCETNIKELERQLQQYREQMQQ 1816
Cdd:COG1196 704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE---EELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
852-1767 |
6.20e-13 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 75.08 E-value: 6.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 852 LKNTQAAEALVKLYETKLCEEEAVIADKNN-----------IENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEM 920
Cdd:TIGR00606 202 VQEHQMELKYLKQYKEKACEIRDQITSKEAqlessreivksYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQM 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 921 FKTYKerdldfdwhkekadQLVERWQNVHVQIDNRLRDLegigkslkyYRDTYHPLDDWIQQVETTQRKIQENQPEnskt 1000
Cdd:TIGR00606 282 EKDNS--------------ELELKMEKVFQGTDEQLNDL---------YHNHQRTVREKERELVDCQRELEKLNKE---- 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1001 lATQLNQQKmlvSEIEMKQSKMdECQKYAEQYSATVKDYELQTMTYRAMVDSQQKSP-----------VKRRRMQSSADL 1069
Cdd:TIGR00606 335 -RRLLNQEK---TELLVEQGRL-QLQADRHQEHIRARDSLIQSLATRLELDGFERGPfserqiknfhtLVIERQEDEAKT 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1070 IIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEhgaysdllqrQKATVLENSKLTGKISELERMVAE 1149
Cdd:TIGR00606 410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEE----------LKFVIKELQQLEGSSDRILELDQE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1150 LKKQksrvEEELPKVREAAENELRKQQ----RNVEDISLQKIRAESEA-------KQYRRELETIVREKEAAERELERVR 1218
Cdd:TIGR00606 480 LRKA----ERELSKAEKNSLTETLKKEvkslQNEKADLDRKLRKLDQEmeqlnhhTTTRTQMEMLTKDKMDKDEQIRKIK 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1219 QLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLI------K 1292
Cdd:TIGR00606 556 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQ 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1293 QMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENAlPVCPITQatscravtglqqeHDKQKAEELKQQVDELT 1372
Cdd:TIGR00606 636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQ-SCCPVCQ-------------RVFQTEAELQEFISDLQ 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1373 AANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKA 1452
Cdd:TIGR00606 702 SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEE 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1453 EEAMQEASDLKKIKRNYQ----------------------LELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHS 1510
Cdd:TIGR00606 782 ESAKVCLTDVTIMERFQMelkdverkiaqqaaklqgsdldRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1511 FR---DEKELERLQICQRKSDhlKEQFEkshEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETK 1587
Cdd:TIGR00606 862 LKsktNELKSEKLQIGTNLQR--RQQFE---EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSN 936
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1588 LM----MQRIQAESENIVLEKQTIQQrcealKIQaDGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEF 1663
Cdd:TIGR00606 937 KKaqdkVNDIKEKVKNIHGYMKDIEN-----KIQ-DGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1664 KQkcdQQNIIIQNTKKEVRNlnaelNASKEEKRRGEQKV-QLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQE 1742
Cdd:TIGR00606 1011 KI---QERWLQDNLTLRKRE-----NELKEVEEELKQHLkEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEK 1082
|
970 980
....*....|....*....|....*..
gi 4502443 1743 ESGKFKQ--SAEEFRKKMEKLMESKVI 1767
Cdd:TIGR00606 1083 EIKHFKKelREPQFRDAEEKYREMMIV 1109
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
882-1615 |
8.79e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 74.71 E-value: 8.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 882 IENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDldfdwhkEKADQLVERWQNVHVQIDNRLRDLEG 961
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE-------EEIEELQKELYALANEISRLEQQKQI 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 962 IGKSLKYYRDTYHPLDDWIQQVETTQRKIQEN---QPENSKTLATQLNQQKMLVSEIEMKQ----SKMDECQKYAEQYSA 1034
Cdd:TIGR02168 307 LRERLANLERQLEELEAQLEELESKLDELAEElaeLEEKLEELKEELESLEAELEELEAELeeleSRLEELEEQLETLRS 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1035 TVKDYELQTMTYRAMV---DSQQKSPVKRRRMQSS------ADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEE 1105
Cdd:TIGR02168 387 KVAQLELQIASLNNEIerlEARLERLEDRRERLQQeieellKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1106 EIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVRE----------AAENELRKQ 1175
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvdegyeaAIEAALGGR 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1176 QRNVEDISLQKIRAESEA-KQYRRELETI-----VREKEAAERELERVRQL-----------TIEAEAKRA--------A 1230
Cdd:TIGR02168 547 LQAVVVENLNAAKKAIAFlKQNELGRVTFlpldsIKGTEIQGNDREILKNIegflgvakdlvKFDPKLRKAlsyllggvL 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1231 VEENLLNFRNQLEENTFTRR--TLEDHL---------KRKDLSLNDLEQQKNklMEELRRKRDNEEELLKLIKQMEKDLA 1299
Cdd:TIGR02168 627 VVDDLDNALELAKKLRPGYRivTLDGDLvrpggvitgGSAKTNSSILERRRE--IEELEEKIEELEEKIAELEKALAELR 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1300 FQKQVAEKQLKEKQKIELEARRKI--TEIQYTCRENAlpvcpITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRK 1377
Cdd:TIGR02168 705 KELEELEEELEQLRKELEELSRQIsaLRKDLARLEAE-----VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1378 AEQDMRELTYELNALQLEKTSSEEKarllkdkLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAmq 1457
Cdd:TIGR02168 780 AEAEIEELEAQIEQLKEELKALREA-------LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL-- 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1458 easdlkkikrnyQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQIcqrksdhlkeqfeKS 1537
Cdd:TIGR02168 851 ------------SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL-------------RE 905
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1538 HEqllqniKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQ-NNETKLMMQRIQAESENIVLEKQTIQQRCEALK 1615
Cdd:TIGR02168 906 LE------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1100-1579 |
2.72e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 72.79 E-value: 2.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1100 KRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAE--NELRKQQR 1177
Cdd:PRK03918 283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKrlEELEERHE 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1178 NVEDI--------SLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTR 1249
Cdd:PRK03918 363 LYEEAkakkeeleRLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1250 RTLEDH-----LKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQmEKDLAFQKQVAE--KQLKEK-QKIELEarr 1321
Cdd:PRK03918 443 RELTEEhrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEqlKELEEKlKKYNLE--- 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1322 kiteiqytcrenalpvcpitqatscravtglQQEHDKQKAEELKQQVDELTAANRKAEQDMRELtyelNALQLEKTSSEE 1401
Cdd:PRK03918 519 -------------------------------ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEK 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1402 KARLLKDKLDETNNTLRCLKLELERKDQAEkgysqqLRELgrqlnqttgkaEEAMQEASDLKKIKRnyqlELESLNHEKG 1481
Cdd:PRK03918 564 KLDELEEELAELLKELEELGFESVEELEER------LKEL-----------EPFYNEYLELKDAEK----ELEREEKELK 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1482 KLQREVDRITRAHAVAEKNIQHLNSQIHSFR---DEKELERL-QICQRKSDHLK------EQFEKSHEQL---LQNIKAE 1548
Cdd:PRK03918 623 KLEEELDKAFEELAETEKRLEELRKELEELEkkySEEEYEELrEEYLELSRELAglraelEELEKRREEIkktLEKLKEE 702
|
490 500 510
....*....|....*....|....*....|.
gi 4502443 1549 KENNDKIQRLNEELEKSNECAEMLKQKVEEL 1579
Cdd:PRK03918 703 LEEREKAKKELEKLEKALERVEELREKVKKY 733
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
2170-2208 |
3.13e-12 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 62.73 E-value: 3.13e-12
10 20 30
....*....|....*....|....*....|....*....
gi 4502443 2170 FLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFRIRL 2208
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1352-1860 |
3.73e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 3.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1352 LQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDEtnntlrcLKLELERKdqae 1431
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-------LELELEEA---- 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1432 kgySQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSF 1511
Cdd:COG1196 287 ---QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1512 ---RDEKELERLQICQRKSDHLKEQFEKSHE------QLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQ 1582
Cdd:COG1196 364 eeaLLEAEAELAEAEEELEELAEELLEALRAaaelaaQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1583 NNETKLMMQRIQAESEN---IVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKclEEDLAKSQNL 1659
Cdd:COG1196 444 LEEAAEEEAELEEEEEAlleLLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK--AALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1660 VSEFKQKCDQ-----------------QNIIIQNTK--KEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQ 1720
Cdd:COG1196 522 LAGAVAVLIGveaayeaaleaalaaalQNIVVEDDEvaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1721 DELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNI 1800
Cdd:COG1196 602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1801 KELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 1860
Cdd:COG1196 682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1514-1846 |
4.85e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.02 E-value: 4.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1514 EKELERLQICQRKSDHLKEQFEKSHEQLlQNIKAEKENNDKIQRLNEELEKSnECAEMLKQKvEELTRQNNETKLMMQRI 1593
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQL-ERLRREREKAERYQALLKEKREY-EGYELLKEK-EALERQKEAIERQLASL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1594 QAESENIVLEKQTIQQRCEALKiqadgfkDQLRSTNEHLHKQTKTEQ-DFQRKIKCLEEDLAKSQNLVSEFKQKcdqqni 1672
Cdd:TIGR02169 250 EEELEKLTEEISELEKRLEEIE-------QLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEKERE------ 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1673 iIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKT--IEE-----QMTHRKMVLFQEESG 1745
Cdd:TIGR02169 317 -LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRaeLEEvdkefAETRDELKDYREKLE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1746 KFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHY 1825
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
|
330 340
....*....|....*....|.
gi 4502443 1826 QKCQKLEDELIAQKREVENLK 1846
Cdd:TIGR02169 476 EEYDRVEKELSKLQRELAEAE 496
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
896-1741 |
7.40e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 71.64 E-value: 7.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 896 VDEKRQVFHALEDELQKA---KAISDEMfktykeRDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDT 972
Cdd:TIGR02169 193 IDEKRQQLERLRREREKAeryQALLKEK------REYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 973 YHPLDDWIQQVEttqRKIQENQPENSKTLATQLNQqkmLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVDS 1052
Cdd:TIGR02169 267 LEEIEQLLEELN---KKIKDLGEEEQLRVKEKIGE---LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1053 QQKS--PVKRRRMQssadlIIQEFMDLRTRYTALVtlmtqyikfagdslKRLEEEEiKRCKETSEhgaysdllqRQKATV 1130
Cdd:TIGR02169 341 LEREieEERKRRDK-----LTEEYAELKEELEDLR--------------AELEEVD-KEFAETRD---------ELKDYR 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1131 LENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAEnelrkqqrnvedislqkiRAESEAKQYRRELETIVREKEAA 1210
Cdd:TIGR02169 392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA------------------GIEAKINELEEEKEDKALEIKKQ 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1211 ERELERVRqltieaeAKRAAVEENLLNFRNQLEEntftrrtLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLK- 1289
Cdd:TIGR02169 454 EWKLEQLA-------ADLSKYEQELYDLKEEYDR-------VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAs 519
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1290 ----------LIKQMEKDLA---------FQKQVAEKQLKEKQKIELEARRKITEIQY----TCRENALPVCPITQATSC 1346
Cdd:TIGR02169 520 iqgvhgtvaqLGSVGERYATaievaagnrLNNVVVEDDAVAKEAIELLKRRKAGRATFlplnKMRDERRDLSILSEDGVI 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1347 RAVTGLQqEHDKQKAEELKQQ------VDELTAANRKAEQdMRELTYE----------------LNALQLEKTSSEEKAR 1404
Cdd:TIGR02169 600 GFAVDLV-EFDPKYEPAFKYVfgdtlvVEDIEAARRLMGK-YRMVTLEgelfeksgamtggsraPRGGILFSRSEPAELQ 677
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1405 LLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQ 1484
Cdd:TIGR02169 678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1485 REVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEK------SHEQLLQNIKAEKEN-NDKIQR 1557
Cdd:TIGR02169 758 SELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRiearlrEIEQKLNRLTLEKEYlEKEIQE 837
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1558 LNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTK 1637
Cdd:TIGR02169 838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRK 917
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1638 TEQDFQRKIKCLEEDLAKSQNLVSEFKQKcDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQK---VQLQQAQVQELNN 1714
Cdd:TIGR02169 918 RLSELKAKLEALEEELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEyeeVLKRLDELKEKRA 996
|
890 900
....*....|....*....|....*..
gi 4502443 1715 RLKKVQDELhLKTIEEQMTHRKMVLFQ 1741
Cdd:TIGR02169 997 KLEEERKAI-LERIEEYEKKKREVFME 1022
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1099-1600 |
1.09e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.86 E-value: 1.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1099 LKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAEnELRKQQRN 1178
Cdd:PRK03918 206 LREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE-ELEEKVKE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1179 VEDI---SLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEEnllnFRNQLEEntfTRRTLEDh 1255
Cdd:PRK03918 285 LKELkekAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE----LKKKLKE---LEKRLEE- 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1256 LKRKDLSLNDLEQQKNKlMEELRRKRDNE--EELLKLIKQMEKDlafQKQVAEKQLKEKQKI-ELEARRKITEIQYTCRE 1332
Cdd:PRK03918 357 LEERHELYEEAKAKKEE-LERLKKRLTGLtpEKLEKELEELEKA---KEEIEEEISKITARIgELKKEIKELKKAIEELK 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1333 NALPVCPItqatsCRAVtgLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQ--LEKTSSEEKARLLKDKL 1410
Cdd:PRK03918 433 KAKGKCPV-----CGRE--LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvLKKESELIKLKELAEQL 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1411 DETNNTLRCLKLE-LERKDQAEKGYSQQLRELG---RQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKL--- 1483
Cdd:PRK03918 506 KELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfe 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1484 -QREVD-RITRAHAVAEKNIQHLNSQIHSFRDEKELERLQicqrksDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEE 1561
Cdd:PRK03918 586 sVEELEeRLKELEPFYNEYLELKDAEKELEREEKELKKLE------EELDKAFEELAETEKRLEELRKELEELEKKYSEE 659
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 4502443 1562 ---------LEKSNECAEmLKQKVEELTRQNNETKLMMQRIQAESENI 1600
Cdd:PRK03918 660 eyeelreeyLELSRELAG-LRAELEELEKRREEIKKTLEKLKEELEER 706
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1155-1899 |
1.19e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 70.59 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1155 SRVEEELpkvrEAAENELRKQQRnvedislQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAE-------AK 1227
Cdd:pfam01576 1 TRQEEEM----QAKEEELQKVKE-------RQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEemrarlaAR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1228 RAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKN---------------------KLMEELRRKRDNEEE 1286
Cdd:pfam01576 70 KQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDeeeaarqklqlekvtteakikKLEEDILLLEDQNSK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1287 LLKLIKQMEKDLA-FQKQVAEKQLKEK--QKIELEARRKITEIQYTCRENALPVCPITQATscRAVTGLQQEHDKQKAeE 1363
Cdd:pfam01576 150 LSKERKLLEERISeFTSNLAEEEEKAKslSKLKNKHEAMISDLEERLKKEEKGRQELEKAK--RKLEGESTDLQEQIA-E 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1364 LKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDEtnntlrcLKLELERKDQAEKGYSQQLRELGR 1443
Cdd:pfam01576 227 LQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISE-------LQEDLESERAARNKAEKQRRDLGE 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1444 QLNQTTGKAEEAMQEAsdlkkikrNYQLELES-LNHEKGKLQREVDRITRAH--AVAEKNIQHlNSQIHSFRDEKE-LER 1519
Cdd:pfam01576 300 ELEALKTELEDTLDTT--------AAQQELRSkREQEVTELKKALEEETRSHeaQLQEMRQKH-TQALEELTEQLEqAKR 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1520 LQICQRKSDHL--KEQFEKSHE-QLLQNIKAEKENNDKiqRLNEELEKsnecaemLKQKVEELTRQNNETKLMMQRIQAE 1596
Cdd:pfam01576 371 NKANLEKAKQAleSENAELQAElRTLQQAKQDSEHKRK--KLEGQLQE-------LQARLSESERQRAELAEKLSKLQSE 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1597 SENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSE---FKQKCDQQ--- 1670
Cdd:pfam01576 442 LESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEeeeAKRNVERQlst 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1671 -NIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQE-------LNNRLKKVQDELHLKTIEEQMTHRKMVLFQE 1742
Cdd:pfam01576 522 lQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEkaaaydkLEKTKNRLQQELDDLLVDLDHQRQLVSNLEK 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1743 ESGKFKQSAEEfrkkmEKLMESKVITENDisgirldfvslqqensRAQENAKLCETNIKELERQLQQYREQMQqgqhmEA 1822
Cdd:pfam01576 602 KQKKFDQMLAE-----EKAISARYAEERD----------------RAEAEAREKETRALSLARALEEALEAKE-----EL 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1823 NHYQKCQKLE-DELIAQK-------REVENLKQKMDQQIKEHEHQLVLLQCEIQkksTAKDCTFKPDFEMTVKECQHSGE 1894
Cdd:pfam01576 656 ERTNKQLRAEmEDLVSSKddvgknvHELERSKRALEQQVEEMKTQLEELEDELQ---ATEDAKLRLEVNMQALKAQFERD 732
|
....*
gi 4502443 1895 LSSRN 1899
Cdd:pfam01576 733 LQARD 737
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1191-1879 |
1.28e-11 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 70.77 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1191 SEAKQYRRELETivrEKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDlEQQK 1270
Cdd:TIGR00618 183 LMEFAKKKSLHG---KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE-QLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1271 NKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQ--KIELEARRKITEIQ--YTCRENALPVCPITQATSC 1346
Cdd:TIGR00618 259 QQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAvtQIEQQAQRIHTELQskMRSRAKLLMKRAAHVKQQS 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1347 RAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLD-ETNNTLRCLKLELE 1425
Cdd:TIGR00618 339 SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDiLQREQATIDTRTSA 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1426 RKD------QAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREvdriTRAHAVAEK 1499
Cdd:TIGR00618 419 FRDlqgqlaHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQE----TRKKAVVLA 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1500 NIQHLNSQIHSFRD---EKELERLQICQRKSDHLK----EQFEKSHEQLLQNIKAE-KENNDKIQRLNEELEKSNECAEM 1571
Cdd:TIGR00618 495 RLLELQEEPCPLCGsciHPNPARQDIDNPGPLTRRmqrgEQTYAQLETSEEDVYHQlTSERKQRASLKEQMQEIQQSFSI 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1572 LKQKVEELTRQNNETKLMMQRIQAESEniVLEKQTIQQRCEAlkiqadgfKDQLRSTNEHLHKQTK--TEQDFQRKIKCL 1649
Cdd:TIGR00618 575 LTQCDNRSKEDIPNLQNITVRLQDLTE--KLSEAEDMLACEQ--------HALLRKLQPEQDLQDVrlHLQQCSQELALK 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1650 EEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQ--VQELNNRLKKVQDELHlkT 1727
Cdd:TIGR00618 645 LTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQtlLRELETHIEEYDREFN--E 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1728 IEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETnIKELERQL 1807
Cdd:TIGR00618 723 IENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL-REEDTHLL 801
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4502443 1808 QQYREQMQQgqhmEANHYQKCQKLEDELIAQKRE-VENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAKDCTFK 1879
Cdd:TIGR00618 802 KTLEAEIGQ----EIPSDEDILNLQCETLVQEEEqFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1258-1854 |
2.99e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 69.32 E-value: 2.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1258 RKDLSLNDLEQQKNKLME---ELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEiqytcrena 1334
Cdd:PRK03918 152 RQILGLDDYENAYKNLGEvikEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREE--------- 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1335 lpvcpitqatscraVTGLQQEhdKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETN 1414
Cdd:PRK03918 223 --------------LEKLEKE--VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1415 NtLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRnyqlELESLNHEKGKLQREVDRITRAH 1494
Cdd:PRK03918 287 E-LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE----RLEELKKKLKELEKRLEELEERH 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1495 AVAEKNIQHLNsqihsfrdekELERLQicQRKSDHLKEQFEKSHEQLLqniKAEKENNDKIQRLNEELEKSNECAEMLKQ 1574
Cdd:PRK03918 362 ELYEEAKAKKE----------ELERLK--KRLTGLTPEKLEKELEELE---KAKEEIEEEISKITARIGELKKEIKELKK 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1575 KVEELTRQNNETKLMMQRIQAESENIVLEKQTIQ-QRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDL 1653
Cdd:PRK03918 427 AIEELKKAKGKCPVCGRELTEEHRKELLEEYTAElKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLK 506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1654 AKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEqkvqlqqaqvqELNNRLKKVQDELH-----LKTI 1728
Cdd:PRK03918 507 ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-----------ELKKKLAELEKKLDeleeeLAEL 575
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1729 EEQMTHRKMVLFQEESGKFKqSAEEFRKKMEKLMESkvitENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQ 1808
Cdd:PRK03918 576 LKELEELGFESVEELEERLK-ELEPFYNEYLELKDA----EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 4502443 1809 QYREQMQQGQHMEAnhYQKCQKLEDELIAQKREVENLKQKMDQQIK 1854
Cdd:PRK03918 651 ELEKKYSEEEYEEL--REEYLELSRELAGLRAELEELEKRREEIKK 694
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1060-1564 |
3.21e-11 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 69.17 E-value: 3.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1060 RRRMQSSADLIIQEFMDLRTRYTALVTLMTQYikfagDSLKRLEE--EEIKRCKETSEHGAYSDLLQRQKATVLENSKLT 1137
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALEDAREQI-----ELLEPIRElaERYAAARERLAELEYLRAALRLWFAQRRLELLE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1138 GKISELERMVAELKKQKSRVEEELPKVREAAEnELRKQQRNVEDISLQKIRAESEAKQyrRELETIVREKEAAErelERV 1217
Cdd:COG4913 295 AELEELRAELARLEAELERLEARLDALREELD-ELEAQIRGNGGDRLEQLEREIERLE--RELEERERRRARLE---ALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1218 RQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEE---LRRKRDN-EEELLKLIKQ 1293
Cdd:COG4913 369 AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEiasLERRKSNiPARLLALRDA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1294 MEKDLAFQK----------QVAEKQLKEKQKIEL-----------------EARRKI------TEIQY------------ 1328
Cdd:COG4913 449 LAEALGLDEaelpfvgeliEVRPEEERWRGAIERvlggfaltllvppehyaAALRWVnrlhlrGRLVYervrtglpdper 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1329 -TCRENALP------VCPITQ-----------ATSCRAVTGLQQ------------------EHDKQ------------- 1359
Cdd:COG4913 529 pRLDPDSLAgkldfkPHPFRAwleaelgrrfdYVCVDSPEELRRhpraitragqvkgngtrhEKDDRrrirsryvlgfdn 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1360 --KAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLD--ETNNTLRCLKLELERKDQAekgyS 1435
Cdd:COG4913 609 raKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDvaSAEREIAELEAELERLDAS----S 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1436 QQLRELGRQLNQttgkAEEAMQEASDlkkikrnyqlELESLNHEKGKLQREVDRitrahavAEKNIQHLNSQIHSFRDEK 1515
Cdd:COG4913 685 DDLAALEEQLEE----LEAELEELEE----------ELDELKGEIGRLEKELEQ-------AEEELDELQDRLEAAEDLA 743
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 4502443 1516 ELERLQICQRKSDHLKEqfEKSHEQLLQNIKAE-KENNDKIQRLNEELEK 1564
Cdd:COG4913 744 RLELRALLEERFAAALG--DAVERELRENLEERiDALRARLNRAEEELER 791
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1132-1623 |
4.15e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.89 E-value: 4.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1132 ENSKLTGKISELERMVAELKKQKSRVEEELPKVreaaENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAE 1211
Cdd:TIGR04523 212 KNKSLESQISELKKQNNQLKDNIEKKQQEINEK----TTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1212 RELErvrQLTIEAEAKRAAVEENLLN-FRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKL 1290
Cdd:TIGR04523 288 KQLN---QLKSEISDLNNQKEQDWNKeLKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1291 IKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQatscravtgLQQEHdkqkaEELKQQVDE 1370
Cdd:TIGR04523 365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKK---------LQQEK-----ELLEKEIER 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1371 LTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTG 1450
Cdd:TIGR04523 431 LKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEE 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1451 KAEEAMQEASDLKKikrnyqlELESLNHEKGKLqrevdritrahavaEKNIQHLNSQIHSFRDEKELERLQIcqrKSDHL 1530
Cdd:TIGR04523 511 KVKDLTKKISSLKE-------KIEKLESEKKEK--------------ESKISDLEDELNKDDFELKKENLEK---EIDEK 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1531 KEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQR 1610
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
|
490
....*....|...
gi 4502443 1611 CEALKIQADGFKD 1623
Cdd:TIGR04523 647 VKQIKETIKEIRN 659
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1099-1538 |
1.48e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 66.71 E-value: 1.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1099 LKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRveEELPKVREAAENELRKQQRN 1178
Cdd:COG4717 70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL--LPLYQELEALEAELAELPER 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1179 VEdislqkiraesEAKQYRRELETIVREKEAAERELERVR-QLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLK 1257
Cdd:COG4717 148 LE-----------ELEERLEELRELEEELEELEAELAELQeELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1258 RKDLSLNDLEQQKNKLMEELRRKRDNEE----------------------ELLKLIKQMEKDLAFQKQVAEKQLKEKQKI 1315
Cdd:COG4717 217 EAQEELEELEEELEQLENELEAAALEERlkearlllliaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLARE 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1316 ELEARRKITEIQYTCRENALpvcpiTQATSCRAVT--GLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELtyELNALQ 1393
Cdd:COG4717 297 KASLGKEAEELQALPALEEL-----EEEELEELLAalGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELE 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1394 lektssEEKARLLKDKLDETNNTLRCLKLELERKDQAEkgysQQLRELGRQLNQTTGKAEEAM---------QEASDLKK 1464
Cdd:COG4717 370 ------QEIAALLAEAGVEDEEELRAALEQAEEYQELK----EELEELEEQLEELLGELEELLealdeeeleEELEELEE 439
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4502443 1465 IKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKN--IQHLNSQIHsfRDEKELERLQICQRKSDHLKEQFEKSH 1538
Cdd:COG4717 440 ELEELEEELEELREELAELEAELEQLEEDGELAELLqeLEELKAELR--ELAEEWAALKLALELLEEAREEYREER 513
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
376-476 |
2.35e-10 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 59.65 E-value: 2.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 376 HNFVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRA 455
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLE 80
|
90 100
....*....|....*....|.
gi 4502443 456 AMQTQWSWILQLCQCVEQHIK 476
Cdd:smart00150 81 ELNERWEELKELAEERRQKLE 101
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1132-1854 |
3.22e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 65.97 E-value: 3.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1132 ENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENElrKQQRNVediSLQKIR-AESEAKQYRRELEtivREKEAA 1210
Cdd:pfam01576 216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEE--TAQKNN---ALKKIReLEAQISELQEDLE---SERAAR 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1211 ERELERVRQLTIEAEAKRAAVEENLLNFRNQLE-------ENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELrrkrdn 1283
Cdd:pfam01576 288 NKAEKQRRDLGEELEALKTELEDTLDTTAAQQElrskreqEVTELKKALEEETRSHEAQLQEMRQKHTQALEEL------ 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1284 eEELLKLIKQMEKDLAFQKQVAEKQLKEKQ---------KIELEARRKITEIQytcrenalpvcpiTQATSCRAVTGLQQ 1354
Cdd:pfam01576 362 -TEQLEQAKRNKANLEKAKQALESENAELQaelrtlqqaKQDSEHKRKKLEGQ-------------LQELQARLSESERQ 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1355 EHDKQ-KAEELKQQVDELTAANRKAEQDMRELTYELNAL--QLEKTSS----EEKARL-LKDKLDETNNTLRCLKLELER 1426
Cdd:pfam01576 428 RAELAeKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLesQLQDTQEllqeETRQKLnLSTRLRQLEDERNSLQEQLEE 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1427 KDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNS 1506
Cdd:pfam01576 508 EEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLV 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1507 QIHSFRdeKELERLQICQRKSDH-LKEQFEKSHEQLLQNIKAEKENNDKIQRLneeLEKSNECAEMLKQKvEELTRQNNE 1585
Cdd:pfam01576 588 DLDHQR--QLVSNLEKKQKKFDQmLAEEKAISARYAEERDRAEAEAREKETRA---LSLARALEEALEAK-EELERTNKQ 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1586 TKLMMQRIQAESENI-----VLE--KQTIQQRCEALKIQADGFKDQLRSTNEHLHK--------QTKTEQDFQRKIKCLE 1650
Cdd:pfam01576 662 LRAEMEDLVSSKDDVgknvhELErsKRALEQQVEEMKTQLEELEDELQATEDAKLRlevnmqalKAQFERDLQARDEQGE 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1651 EDLAKSQNLVSEFKQKCD----QQNIIIQNTKK---EVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKV---- 1719
Cdd:pfam01576 742 EKRRQLVKQVRELEAELEderkQRAQAVAAKKKlelDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEArasr 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1720 --------QDELHLKTIEEQMTHrkmvlFQEE---SGKFKQSAEEFRKKMEKLMES----KVITENDISGIRLDFVSLQQ 1784
Cdd:pfam01576 822 deilaqskESEKKLKNLEAELLQ-----LQEDlaaSERARRQAQQERDELADEIASgasgKSALQDEKRRLEARIAQLEE 896
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1785 ENSRAQENAKLcetnIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIK 1854
Cdd:pfam01576 897 ELEEEQSNTEL----LNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVK 962
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
868-1602 |
3.24e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 66.24 E-value: 3.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 868 KLCEEEAVIADKNNIENLISTLK----QWRSEVDEKRQVFHALEDELQ----KAKAISDEMFKTYKERDLDF-------- 931
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEeeleKLTEEISELEKRLEEIEQLLEelnkKIKDLGEEEQLRVKEKIGELeaeiasle 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 932 ---DWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQ 1008
Cdd:TIGR02169 308 rsiAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1009 KMLVSEIEMKQSKMDECQKyaeqysatvkdyelqtmtyramvdsqqkspvKRRRMQSSADLIIQEFMDLRTRYTALVTLM 1088
Cdd:TIGR02169 388 KDYREKLEKLKREINELKR-------------------------------ELDRLQEELQRLSEELADLNAAIAGIEAKI 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1089 TQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVlenSKLTGKISELERMVAELKKQKSRVEE--------- 1159
Cdd:TIGR02169 437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY---DRVEKELSKLQRELAEAEAQARASEErvrggrave 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1160 ---------------ELPKVRE--------AAENelRKQQRNVED---------------------ISLQKIRAESEAKQ 1195
Cdd:TIGR02169 514 evlkasiqgvhgtvaQLGSVGEryataievAAGN--RLNNVVVEDdavakeaiellkrrkagratfLPLNKMRDERRDLS 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1196 YRRELETI--------------------------VREKEAAERELERVRQLTIEAE--AKRAAVEEnllNFRNQLEENTF 1247
Cdd:TIGR02169 592 ILSEDGVIgfavdlvefdpkyepafkyvfgdtlvVEDIEAARRLMGKYRMVTLEGElfEKSGAMTG---GSRAPRGGILF 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1248 TRRtLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDL----AFQKQVAEKQLKEKQKIElEARRKI 1323
Cdd:TIGR02169 669 SRS-EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIgeieKEIEQLEQEEEKLKERLE-ELEEDL 746
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1324 TEIQYTcRENAlpvcpITQATSCRAVTGLQQEhdkqKAEELKQQVDELTAanRKAEQDMRELTYELNAlqLEKTSSEEKA 1403
Cdd:TIGR02169 747 SSLEQE-IENV-----KSELKELEARIEELEE----DLHKLEEALNDLEA--RLSHSRIPEIQAELSK--LEEEVSRIEA 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1404 RllkdkLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKL 1483
Cdd:TIGR02169 813 R-----LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDL 887
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1484 QREVDRITRAHAVAEKNIQHLNSQIHSFRD--EKELERLQICQRKSDHL-----KEQFEKSHEQLLQNIKAEKEnndKIQ 1556
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKrlSELKAKLEALEEELSEIedpkgEDEEIPEEELSLEDVQAELQ---RVE 964
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 4502443 1557 RLNEELEKSNECAEmlkQKVEELTRQNNETKLMMQRIQAESENIVL 1602
Cdd:TIGR02169 965 EEIRALEPVNMLAI---QEYEEVLKRLDELKEKRAKLEEERKAILE 1007
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1103-1779 |
4.29e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 65.76 E-value: 4.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1103 EEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVE-- 1180
Cdd:pfam02463 293 KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQle 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1181 ---DISLQKIRAESEAKQYRRELETIVREKEAAER----ELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLE 1253
Cdd:pfam02463 373 eelLAKKKLESERLSSAAKLKEEELELKSEEEKEAqlllELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEE 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1254 DHLKRKDLSLNDLEQQKNKLMEELRRKRDNE---EELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTC 1330
Cdd:pfam02463 453 LEKQELKLLKDELELKKSEDLLKETQLVKLQeqlELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1331 R-ENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDK 1409
Cdd:pfam02463 533 DlGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKAT 612
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1410 LDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKI-KRNYQLELESLNHEKGKLQREVD 1488
Cdd:pfam02463 613 LEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLsELTKELLEIQELQEKAESELAKE 692
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1489 RITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNI-KAEKENNDKIQRLNEELEKSNE 1567
Cdd:pfam02463 693 EILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEeEEEKSRLKKEEKEEEKSELSLK 772
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1568 CAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQ-QRCEALKIQADGFKDQLRSTNEHLHKQTKTEQ-----D 1641
Cdd:pfam02463 773 EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEaELLEEEQLLIEQEEKIKEEELEELALELKEEQkleklA 852
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1642 FQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRG------EQKVQLQQAQVQELNNR 1715
Cdd:pfam02463 853 EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLnlleekENEIEERIKEEAEILLK 932
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1716 LKKVQDELHL---KTIEEQMTHRKMVL---------FQEESGKFKQSAEEFRKKMEK----LMESKVITENDISGIRLDF 1779
Cdd:pfam02463 933 YEEEPEELLLeeaDEKEKEENNKEEEEernkrlllaKEELGKVNLMAIEEFEEKEERynkdELEKERLEEEKKKLIRAII 1012
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1223-1445 |
4.65e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 64.40 E-value: 4.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1223 EAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQK 1302
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1303 QVAEKQLKEKQKIELEARRKIteiqytcrenALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDM 1382
Cdd:COG4942 104 EELAELLRALYRLGRQPPLAL----------LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4502443 1383 RELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQL 1445
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1135-1583 |
5.67e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.79 E-value: 5.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1135 KLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELE--TIVREKEAAER 1212
Cdd:COG4717 60 KPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1213 EL----ERVRQLT------IEAEAKRAAVEENLLNFRNQLEE-NTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKR 1281
Cdd:COG4717 140 ELaelpERLEELEerleelRELEEELEELEAELAELQEELEElLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1282 DNEEELLKLIKQMEKDLAFQKQvaEKQLKEkQKIELEARRKITEIQYTCRENALPVCPITQATSCRA-VTGLQQEHDKQK 1360
Cdd:COG4717 220 EELEELEEELEQLENELEAAAL--EERLKE-ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLgLLALLFLLLARE 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1361 AEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRclKLELERKDQAEKGYSQQLRE 1440
Cdd:COG4717 297 KASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR--EAEELEEELQLEELEQEIAA 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1441 LgrqLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH---EKGKLQREVDRITRAHAVAEKnIQHLNSQIHSFrdEKEL 1517
Cdd:COG4717 375 L---LAEAGVEDEEELRAALEQAEEYQELKEELEELEEqleELLGELEELLEALDEEELEEE-LEELEEELEEL--EEEL 448
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1518 ERLQICQRKSDHLKEQFEKSHEqlLQNIKAEKEN-NDKIQRLNEELEKSNECAEMLKQKVEELTRQN 1583
Cdd:COG4717 449 EELREELAELEAELEQLEEDGE--LAELLQELEElKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
811-1273 |
5.73e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 65.14 E-value: 5.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 811 AAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLK-TVNLVLKNTQAAEalvKLYETKLCEEEAVIADKNnienliSTL 889
Cdd:pfam15921 288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLEsTVSQLRSELREAK---RMYEDKIEELEKQLVLAN------SEL 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 890 KQWRSEVDEKRQVFHALEDELQKAKAisdEMFKTYKERDLDfdwhKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYY 969
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLA---DLHKREKELSLE----KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRL 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 970 RDTYHPLDDWIQ-QVETTQRKIQ-ENQP-ENSKTLATQLNQQKML----VSEIEMKQSKMDECQKYAEQYSATVKDYElq 1042
Cdd:pfam15921 432 EALLKAMKSECQgQMERQMAAIQgKNESlEKVSSLTAQLESTKEMlrkvVEELTAKKMTLESSERTVSDLTASLQEKE-- 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1043 tmtyRAMvdsqQKSPVKRRRMQSSADLIIQEFmdlrtrytalvtlmtQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDL 1122
Cdd:pfam15921 510 ----RAI----EATNAEITKLRSRVDLKLQEL---------------QHLKNEGDHLRNVQTECEALKLQMAEKDKVIEI 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1123 LQRQKATVLENSKLTGKIS---ELERMVAELKKQKSRVE-EELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRR 1198
Cdd:pfam15921 567 LRQQIENMTQLVGQHGRTAgamQVEKAQLEKEINDRRLElQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1199 ELETIVREKEAAERELERVRQltiEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRkdlSLNDLEQQKNKL 1273
Cdd:pfam15921 647 AVKDIKQERDQLLNEVKTSRN---ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKS---AQSELEQTRNTL 715
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
747-1574 |
8.42e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 64.60 E-value: 8.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 747 RNIRLRLENCEDRLIRQIRtpLERDDLHESVFRITEQEKLKKELERLKDDLGTITN-------KCEEFFSQAaasssvPT 819
Cdd:TIGR00618 92 RTLRCTRSHRKTEQPEQLY--LEQKKGRGRILAAKKSETEEVIHDLLKLDYKTFTRvvllpqgEFAQFLKAK------SK 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 820 LRSELNVVLQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEALVKLyetklCEEEAVIADKNNIENLISTLKQWRSEVDEK 899
Cdd:TIGR00618 164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL-----CTPCMPDTYHERKQVLEKELKHLREALQQT 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 900 RQVFHALEDELQKAKAISdemfktykerdldfdwhkekadqlveRWQNVHVQIDNRLRDLEGIGKSLKyyrdtyhplddw 979
Cdd:TIGR00618 239 QQSHAYLTQKREAQEEQL--------------------------KKQQLLKQLRARIEELRAQEAVLE------------ 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 980 IQQVETTQRKIQENQPENSKTLaTQLNQQKMLV-SEIemkQSKMDECQKYAEQYSATVKDyELQTMTYRAMVDSQQKSPV 1058
Cdd:TIGR00618 281 ETQERINRARKAAPLAAHIKAV-TQIEQQAQRIhTEL---QSKMRSRAKLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEI 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1059 KRRRMQSSADLIIQEF---MDLRTRYTAL---VTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAysdlLQRQKATVLE 1132
Cdd:TIGR00618 356 HIRDAHEVATSIREIScqqHTLTQHIHTLqqqKTTLTQKLQSLCKELDILQREQATIDTRTSAFRD----LQGQLAHAKK 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1133 NSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAER 1212
Cdd:TIGR00618 432 QQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCI 511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1213 ELERVRQLTIEAEA----------KRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRD 1282
Cdd:TIGR00618 512 HPNPARQDIDNPGPltrrmqrgeqTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN 591
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1283 NEEELLKLIkQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALpvcpiTQATSCRAVTGLQQEHDKQKAE 1362
Cdd:TIGR00618 592 ITVRLQDLT-EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELAL-----KLTALHALQLTLTQERVREHAL 665
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1363 ELKQQVDELTAANRKAEQDM----RELTY---ELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAekgYS 1435
Cdd:TIGR00618 666 SIRVLPKELLASRQLALQKMqsekEQLTYwkeMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDA---LN 742
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1436 QQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREvdRITRAHAVAEKNIQHlNSQIHSFRDEK 1515
Cdd:TIGR00618 743 QSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL--REEDTHLLKTLEAEI-GQEIPSDEDIL 819
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1516 ELERLQICQRKsDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQ 1574
Cdd:TIGR00618 820 NLQCETLVQEE-EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1100-1317 |
8.71e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 63.24 E-value: 8.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1100 KRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSK----LTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQ 1175
Cdd:COG4942 34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARriraLEQELAALEAELAELEKEIAELRAELEAQKEELAELLRAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1176 QRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDH 1255
Cdd:COG4942 114 YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAL 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4502443 1256 LKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIEL 1317
Cdd:COG4942 194 KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1097-1614 |
1.57e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 63.52 E-value: 1.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1097 DSLKRLEEEEIkRCKETSEhgAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAEnELRKQQ 1176
Cdd:PRK02224 220 EEIERYEEQRE-QARETRD--EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE-ELEEER 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1177 R-----------NVEDISLQKIRAESEAKQYRRELET----IVREKEAAERELERVRQLTIEAEAKR---AAVEENLLNF 1238
Cdd:PRK02224 296 DdllaeaglddaDAEAVEARREELEDRDEELRDRLEEcrvaAQAHNEEAESLREDADDLEERAEELReeaAELESELEEA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1239 RNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLafqkQVAEKQLKEKQKIeLE 1318
Cdd:PRK02224 376 REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATL----RTARERVEEAEAL-LE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1319 ARRkiteiqytCRENALPV--CPITQATscravtglqqEHDKQKAEELKQQVDELTAANRKAEQDMRELTyELNALQLEK 1396
Cdd:PRK02224 451 AGK--------CPECGQPVegSPHVETI----------EEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRI 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1397 TSSEEKARLLKDKLDETNNTLRclklelERKDQAEkgysqQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNyqlELESL 1476
Cdd:PRK02224 512 ERLEERREDLEELIAERRETIE------EKRERAE-----ELRERAAELEAEAEEKREAAAEAEEEAEEARE---EVAEL 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1477 NHEKGKLQREVDRITRAHAVAEKnIQHLNSQIHSFRDEKELERLQICQRKsDHLKEQFEKsHEQLlqnikAEKENNDKIQ 1556
Cdd:PRK02224 578 NSKLAELKERIESLERIRTLLAA-IADAEDEIERLREKREALAELNDERR-ERLAEKRER-KREL-----EAEFDEARIE 649
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4502443 1557 RLNEELEKSNECAEMLKQKVEELTRQNNETKL---MMQRIQAESENIVLEKQTIQQRCEAL 1614
Cdd:PRK02224 650 EAREDKERAEEYLEQVEEKLDELREERDDLQAeigAVENELEELEELRERREALENRVEAL 710
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
989-1591 |
1.79e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 63.59 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 989 KIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTmtyrAMVDSQQKSPVKRRrmqssaD 1068
Cdd:pfam05483 223 KIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKT----KLQDENLKELIEKK------D 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1069 LIIQEFMDLRT---RYTALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSE-HGAYSDLLQRQKATV--------LENSKL 1136
Cdd:pfam05483 293 HLTKELEDIKMslqRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKaKAAHSFVVTEFEATTcsleellrTEQQRL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1137 TGKISELERMVAELKKQKSRVeEELPKVREAAENELRKqqrnvedisLQKIRAESEAKQY-RRELETIVREKEAAERELE 1215
Cdd:pfam05483 373 EKNEDQLKIITMELQKKSSEL-EEMTKFKNNKEVELEE---------LKKILAEDEKLLDeKKQFEKIAEELKGKEQELI 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1216 RVRQltiEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQME 1295
Cdd:pfam05483 443 FLLQ---AREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1296 KDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTcrenalpvcpitqatscravtglqqehdkqkAEELKQQVDELTAAN 1375
Cdd:pfam05483 520 EDIINCKKQEERMLKQIENLEEKEMNLRDELESV-------------------------------REEFIQKGDEVKCKL 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1376 RKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLE---LERKDQAEkgySQQLRELGRQLNQTTGKA 1452
Cdd:pfam05483 569 DKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkaLKKKGSAE---NKQLNAYEIKVNKLELEL 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1453 EEAMQEasdLKKIKRNYQLELESLNHEKGKLQREVDritRAHAVAEKNIQhLNSQIHSFRDEKELERLQICQRKSDHLKE 1532
Cdd:pfam05483 646 ASAKQK---FEEIIDNYQKEIEDKKISEEKLLEEVE---KAKAIADEAVK-LQKEIDKRCQHKIAEMVALMEKHKHQYDK 718
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1533 QFEKSHEQLlqNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQ 1591
Cdd:pfam05483 719 IIEERDSEL--GLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKME 775
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1213-1870 |
1.80e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 63.45 E-value: 1.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1213 ELERVRQLTIEAEA--KRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSlnDLEQQknkLMEELRRKRDNEEELLKL 1290
Cdd:TIGR00618 174 PLDQYTQLALMEFAkkKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLE--KELKH---LREALQQTQQSHAYLTQK 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1291 IKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQATscravtglqqEHDKQKAEELKQQVDE 1370
Cdd:TIGR00618 249 REAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAV----------TQIEQQAQRIHTELQS 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1371 ltaanrkaeqDMRELTYEL---NALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYS--QQLRELGRQL 1445
Cdd:TIGR00618 319 ----------KMRSRAKLLmkrAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTltQHIHTLQQQK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1446 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSfrdEKELERLQICQR 1525
Cdd:TIGR00618 389 TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQC---EKLEKIHLQESA 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1526 KSDHLKEQFEKSHEQLLQniKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQ 1605
Cdd:TIGR00618 466 QSLKEREQQLQTKEQIHL--QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1606 TiqqrcEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNiiiqNTKKEVRNLN 1685
Cdd:TIGR00618 544 E-----EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLS----EAEDMLACEQ 614
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1686 AELNASKEEKRRGEQKVQLQQAQVQELNNRL-KKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAE-EFRKKMEKLME 1763
Cdd:TIGR00618 615 HALLRKLQPEQDLQDVRLHLQQCSQELALKLtALHALQLTLTQERVREHALSIRVLPKELLASRQLALqKMQSEKEQLTY 694
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1764 SKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQ-------LQQYREQMQQGQHMEANHYQKCQKLEDELI 1836
Cdd:TIGR00618 695 WKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARedalnqsLKELMHQARTVLKARTEAHFNNNEEVTAAL 774
|
650 660 670
....*....|....*....|....*....|....*..
gi 4502443 1837 AQKREVENLKQKMDQQIKEHE---HQLVLLQCEIQKK 1870
Cdd:TIGR00618 775 QTGAELSHLAAEIQFFNRLREedtHLLKTLEAEIGQE 811
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1423-1878 |
2.47e-09 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 63.32 E-value: 2.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1423 ELERKDQAEKGYSQQLRELGRQLNQttgKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQRevDRITRAHAVAEkniq 1502
Cdd:pfam12128 277 RQEERQETSAELNQLLRTLDDQWKE---KRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQE---- 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1503 hlnsQIHSFRDEKEL--ERLQICQRKSDHLKEQFEKsheqLLQNIKaeKENNDKIQRLNEELEKSNECAEMLKQkVEELT 1580
Cdd:pfam12128 348 ----QLPSWQSELENleERLKALTGKHQDVTAKYNR----RRSKIK--EQNNRDIAGIKDKLAKIREARDRQLA-VAEDD 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1581 RQNNETKLMMQRIQAESEnivlekqtiqqrceaLKIQADGFKDQLRSTNEHLHKQTKTEQdfqrkikcLEEDLAKSQNLV 1660
Cdd:pfam12128 417 LQALESELREQLEAGKLE---------------FNEEEYRLKSRLGELKLRLNQATATPE--------LLLQLENFDERI 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1661 SEFKQKCDQQNiiiqntkKEVRNLNAELNASKeeKRRGEQKVQLQQAQ--VQELNNRLKKVQDELHLKTIEEQMTHRKMV 1738
Cdd:pfam12128 474 ERAREEQEAAN-------AEVERLQSELRQAR--KRRDQASEALRQASrrLEERQSALDELELQLFPQAGTLLHFLRKEA 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1739 LFQEES-GKFKQSAEEFRKKME-KLMESKVITENDISGIRLDFVSLQQENSRAQEN------AKLCET------NIKELE 1804
Cdd:pfam12128 545 PDWEQSiGKVISPELLHRTDLDpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEelrerlDKAEEAlqsareKQAAAE 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1805 RQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEH-----------EHQLVLLQCEIQKKSTA 1873
Cdd:pfam12128 625 EQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERkdsanerlnslEAQLKQLDKKHQAWLEE 704
|
....*
gi 4502443 1874 KDCTF 1878
Cdd:pfam12128 705 QKEQK 709
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1326 |
6.60e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.32 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 883 ENLISTLKQWRSEVDEKRQV---FHALEDELQKAKAISDEMFKTYKERDLDFDwHKEKADQLVERWQNVHvQIDNRLRDL 959
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKeeeYAELQEELEELEEELEELEAELEELREELE-KLEKLLQLLPLYQELE-ALEAELAEL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 960 EGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQE--------NQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQ 1031
Cdd:COG4717 145 PERLEELEERLEELRELEEELEELEAELAELQEeleelleqLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1032 YSATVKDYELQtmtyrAMVDSQQKSPVKRRRMQSSADLII------QEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEE 1105
Cdd:COG4717 225 LEEELEQLENE-----LEAAALEERLKEARLLLLIAAALLallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1106 EIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKIS-----ELERMVAELKKQKSRVEEELpkvREAAENELRKQQRNVe 1180
Cdd:COG4717 300 LGKEAEELQALPALEELEEEELEELLAALGLPPDLSpeellELLDRIEELQELLREAEELE---EELQLEELEQEIAAL- 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1181 disLQKIRAESEAkqyrrELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLlnfrnqleeNTFTRRTLEDHLKRKD 1260
Cdd:COG4717 376 ---LAEAGVEDEE-----ELRAALEQAEEYQELKEELEELEEQLEELLGELEELL---------EALDEEELEEELEELE 438
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4502443 1261 LSLNDLEQQKNKLMEELRrkrdneeELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Cdd:COG4717 439 EELEELEEELEELREELA-------ELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1104-1586 |
6.64e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.59 E-value: 6.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1104 EEEIKRCKET-----SEHGAYSDLLQRQKATVLE-NSKLTGKISE----------LERMVAELKKQKSRVEEELPKVREA 1167
Cdd:PRK02224 257 EAEIEDLRETiaeteREREELAEEVRDLRERLEElEEERDDLLAEaglddadaeaVEARREELEDRDEELRDRLEECRVA 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1168 AENELRKQQRNVEDISlqkiRAESEAKQYRRELETIVREKEAAERELErvrqltiEAEAKRAAVEENLLNFRNQLEENTF 1247
Cdd:PRK02224 337 AQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVE-------DRREEIEELEEEIEELRERFGDAPV 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1248 TRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIK-----QMEKDLAFQKQVAEKQLKEKQKIELEARRK 1322
Cdd:PRK02224 406 DLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEGSPHVETIEEDRERVEELEAELE 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1323 ITEIQYTCRENALPVCPITQATSCRAVTGLQQ---------------EHDKQKAEELKQQVDELTAANRKAE-------- 1379
Cdd:PRK02224 486 DLEEEVEEVEERLERAEDLVEAEDRIERLEERredleeliaerretiEEKRERAEELRERAAELEAEAEEKReaaaeaee 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1380 --QDMRELTYELNALQLEKTSSEEKARLLKDKLDE-TNNTLRCLKLELERKDQAE-----KGYSQQLRELGRQLNQTTGK 1451
Cdd:PRK02224 566 eaEEAREEVAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAElnderRERLAEKRERKRELEAEFDE 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1452 A--EEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRItrahavaekniqhlnsqihsfrdEKELERLQICQRKSDH 1529
Cdd:PRK02224 646 AriEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAV-----------------------ENELEELEELRERREA 702
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1530 LKEQFEKsheqllqnIKAEKENNDKIQRLNEELEksnecAEMLKQKVEELTRQNNET 1586
Cdd:PRK02224 703 LENRVEA--------LEALYDEAEELESMYGDLR-----AELRQRNVETLERMLNET 746
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1142-1487 |
9.86e-09 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 60.91 E-value: 9.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1142 ELERMVAE-LKKQKSRVEEELPKVREAAENElrkQQRNVEDISLQKIRAESE--AKQYRRELETIvrEKEAAERELERVR 1218
Cdd:pfam17380 292 KFEKMEQErLRQEKEEKAREVERRRKLEEAE---KARQAEMDRQAAIYAEQErmAMERERELERI--RQEERKRELERIR 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1219 QLTIEAEAKRAAVEENLLNFRNQleENTFTRRTLEDHLKRKDL--SLNDLEQQKNKLMEELRRKRDN--EEELLKLIKQM 1294
Cdd:pfam17380 367 QEEIAMEISRMRELERLQMERQQ--KNERVRQELEAARKVKILeeERQRKIQQQKVEMEQIRAEQEEarQREVRRLEEER 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1295 EKDLafqKQVAEKQLKEKQKIEL------EARRKITEIQytcrenalpvcpitqatscravtglQQEHDKQKAEELKQQV 1368
Cdd:pfam17380 445 AREM---ERVRLEEQERQQQVERlrqqeeERKRKKLELE-------------------------KEKRDRKRAEEQRRKI 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1369 DELTAANRKaeQDMREltyelnalqlektsSEEKARLLKDKLDETNNTlrcLKLELERKDQAEKGYSQQLRELGRQLNQT 1448
Cdd:pfam17380 497 LEKELEERK--QAMIE--------------EERKRKLLEKEMEERQKA---IYEEERRREAEEERRKQQEMEERRRIQEQ 557
|
330 340 350
....*....|....*....|....*....|....*....
gi 4502443 1449 TGKAEEamqEASDLKKIKRNYQLELESLNHEKGKLQREV 1487
Cdd:pfam17380 558 MRKATE---ERSRLEAMEREREMMRQIVESEKARAEYEA 593
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1502-1810 |
1.28e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 60.52 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1502 QHLNSQIHSFRDEKEL-ERLQicqrksdhlKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNEcAEMLKQ------ 1574
Cdd:pfam17380 269 EFLNQLLHIVQHQKAVsERQQ---------QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ-AEMDRQaaiyae 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1575 -------KVEELTR-QNNETKLMMQRIQAES-----------ENIVLEKQT----IQQRCEALKIQADGFKDQLRSTNEH 1631
Cdd:pfam17380 339 qermameRERELERiRQEERKRELERIRQEEiameisrmrelERLQMERQQknerVRQELEAARKVKILEEERQRKIQQQ 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1632 LHKQTKT----EQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNasKEEKRRGEQKVQLQQA 1707
Cdd:pfam17380 419 KVEMEQIraeqEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELE--KEKRDRKRAEEQRRKI 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1708 QVQELN-NRLKKVQDELHLKTIEEQMTHRKMVLFQEESgkfKQSAEEFRKKMEKLMESKVITEndisgiRLDFVSLQQEN 1786
Cdd:pfam17380 497 LEKELEeRKQAMIEEERKRKLLEKEMEERQKAIYEEER---RREAEEERRKQQEMEERRRIQE------QMRKATEERSR 567
|
330 340
....*....|....*....|....
gi 4502443 1787 SRAQENAKLCETNIKELERQLQQY 1810
Cdd:pfam17380 568 LEAMEREREMMRQIVESEKARAEY 591
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
2244-2282 |
1.76e-08 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 52.33 E-value: 1.76e-08
10 20 30
....*....|....*....|....*....|....*....
gi 4502443 2244 ILEAQIASGGVIDPVRGIRVPPEIALQQGLLNNAILQFL 2282
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1635-1855 |
2.08e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.01 E-value: 2.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1635 QTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNN 1714
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1715 RLKKVQDELHLKTIEEQMTHR----KMVLFQEESGKFKQSAEEFRKKMEKLMEskvitenDISGIRLDFVSLQQENSRAQ 1790
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARRE-------QAEELRADLAELAALRAELE 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1791 ENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKE 1855
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
2556-2593 |
4.77e-08 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 50.79 E-value: 4.77e-08
10 20 30
....*....|....*....|....*....|....*...
gi 4502443 2556 LEFQYLTGGLIEPQVHSRLSIEEALQVGIIDVLIATKL 2593
Cdd:pfam00681 2 LEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
761-1326 |
4.85e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.92 E-value: 4.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 761 IRQ--IRTPLERDDLHESVFR-ITEQEKLKKELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSELNVVL-QNMNQVYS 836
Cdd:PRK03918 132 IRQgeIDAILESDESREKVVRqILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELeEVLREINE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 837 MSSTYIDKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAI 916
Cdd:PRK03918 212 ISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 917 SDEMFKTYKERDlDFDWHKEKADQLVERWQNVHVQIDNRLRDLEG-------IGKSLKYYRDTYHPLDDWIQQVETTQRK 989
Cdd:PRK03918 292 AEEYIKLSEFYE-EYLDELREIEKRLSRLEEEINGIEERIKELEEkeerleeLKKKLKELEKRLEELEERHELYEEAKAK 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 990 iqENQPENSKTLATQLNQQKmLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVD----SQQKSPVKRRrmqs 1065
Cdd:PRK03918 371 --KEELERLKKRLTGLTPEK-LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEelkkAKGKCPVCGR---- 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1066 saDLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQ--------------------R 1125
Cdd:PRK03918 444 --ELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaeqlkeleeklkkynleelE 521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1126 QKATVLENSK-----LTGKISELERMV---AELKKQKSRVEEELPKVREAAENELRK-QQRNVEDISLQKIRAESEAKQY 1196
Cdd:PRK03918 522 KKAEEYEKLKeklikLKGEIKSLKKELeklEELKKKLAELEKKLDELEEELAELLKElEELGFESVEELEERLKELEPFY 601
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1197 RR--ELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEE--------------NTFTRrtLEDHLKRKD 1260
Cdd:PRK03918 602 NEylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEElekkyseeeyeelrEEYLE--LSRELAGLR 679
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1261 LSLNDLEQQKN---KLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Cdd:PRK03918 680 AELEELEKRREeikKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEI 748
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1103-1817 |
5.14e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 58.65 E-value: 5.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1103 EEEEIKRC--KETSEHGA-YSDLLQRQKATVLEnskLTGKISELERMVAELKKQKSRVEEElpkvreaaENELRKQQRnv 1179
Cdd:pfam01576 328 EVTELKKAleEETRSHEAqLQEMRQKHTQALEE---LTEQLEQAKRNKANLEKAKQALESE--------NAELQAELR-- 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1180 ediSLQKIRAESEAKqyRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRR----TLEDH 1255
Cdd:pfam01576 395 ---TLQQAKQDSEHK--RKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkdvsSLESQ 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1256 LKRKDLSLNDLEQQKNKLMEELRRKrdnEEELLKLIKQMEKDLAfQKQVAEKQLKEKQKIELEARRKITEIQYTcrenal 1335
Cdd:pfam01576 470 LQDTQELLQEETRQKLNLSTRLRQL---EDERNSLQEQLEEEEE-AKRNVERQLSTLQAQLSDMKKKLEEDAGT------ 539
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1336 pvcpITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNN 1415
Cdd:pfam01576 540 ----LEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKA 615
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1416 TlrCLKLELERkDQAEKgysqQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHA 1495
Cdd:pfam01576 616 I--SARYAEER-DRAEA----EAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKR 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1496 VAEKNIQHLNSQIHSFRDE---KELERLQIcQRKSDHLKEQFEKSheqlLQNikAEKENNDKIQRLNEEL-EKSNECAEM 1571
Cdd:pfam01576 689 ALEQQVEEMKTQLEELEDElqaTEDAKLRL-EVNMQALKAQFERD----LQA--RDEQGEEKRRQLVKQVrELEAELEDE 761
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1572 LKQKVEELT-RQNNETKLMMQRIQAESENIVLEKQTIQQRcealKIQADgFKDQLRSTNEHLHKQTK---TEQDFQRKIK 1647
Cdd:pfam01576 762 RKQRAQAVAaKKKLELDLKELEAQIDAANKGREEAVKQLK----KLQAQ-MKDLQRELEEARASRDEilaQSKESEKKLK 836
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1648 CLE-------EDLAKSQNLVSEFKQKCDQqniiiqnTKKEVRNLNAELNASKEEKRRGEQKV-QLQ------QAQVQELN 1713
Cdd:pfam01576 837 NLEaellqlqEDLAASERARRQAQQERDE-------LADEIASGASGKSALQDEKRRLEARIaQLEeeleeeQSNTELLN 909
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1714 NRLKKVQdeLHLKTIEEQMTHRKMVLFQEESGK--FKQSAEEFRKKMEKlMESKVITE--NDISGIRLDFVS----LQQE 1785
Cdd:pfam01576 910 DRLRKST--LQVEQLTTELAAERSTSQKSESARqqLERQNKELKAKLQE-MEGTVKSKfkSSIAALEAKIAQleeqLEQE 986
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 4502443 1786 NSRAQENAKLC---ETNIKEL-------ERQLQQYREQMQQG 1817
Cdd:pfam01576 987 SRERQAANKLVrrtEKKLKEVllqvedeRRHADQYKDQAEKG 1028
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2170-2205 |
7.05e-08 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 50.56 E-value: 7.05e-08
10 20 30
....*....|....*....|....*....|....*.
gi 4502443 2170 FLEAQAATGFIIDPISGQTYSVEDAVLKGVVDPEFR 2205
Cdd:smart00250 3 LLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2477-2514 |
9.55e-08 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 50.17 E-value: 9.55e-08
10 20 30
....*....|....*....|....*....|....*...
gi 4502443 2477 LRCLEAQVSTGGIIDPLTGKKYRVAEALHRGLVDEGFA 2514
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
620-1854 |
9.62e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 58.14 E-value: 9.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 620 KEAVDLANRIEQqyqnvltlwHESHINMKSVVSwHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLedsQE 699
Cdd:TIGR01612 620 KKAIDLKKIIEN---------NNAYIDELAKIS-PYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIV---KE 686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 700 SQVFSGSDITQLEKEVNVCKQYYQELlksaerEEQEESVYNLYISEVRNIRLRLENCEDRLIRQIRTPLERDdLHESV-- 777
Cdd:TIGR01612 687 NAIDNTEDKAKLDDLKSKIDKEYDKI------QNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD-LNKILed 759
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 778 FRITEQEKLKK--ELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSElnvvlqNMNQVYSMSSTYIdklKTVNLvlknt 855
Cdd:TIGR01612 760 FKNKEKELSNKinDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDE------DAKQNYDKSKEYI---KTISI----- 825
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 856 QAAEALVKLYETKLCEEEAViadkNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAkaISDEMFKTYKERDLDF-DWH 934
Cdd:TIGR01612 826 KEDEIFKIINEMKFMKDDFL----NKVDKFINFENNCKEKIDSEHEQFAELTNKIKAE--ISDDKLNDYEKKFNDSkSLI 899
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 935 KEKADQLVERWQNVHV--QIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQ-VETTQ-----RKIQENQPENskTLATQLN 1006
Cdd:TIGR01612 900 NEINKSIEEEYQNINTlkKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKesnliEKSYKDKFDN--TLIDKIN 977
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1007 QQKMLVSEIEMK--QSKMDECQKYAEQYSATVKDYELQTMTY------RAMVDSQQKSpVKRRRMQSSADLIIqefmdlr 1078
Cdd:TIGR01612 978 ELDKAFKDASLNdyEAKNNELIKYFNDLKANLGKNKENMLYHqfdekeKATNDIEQKI-EDANKNIPNIEIAI------- 1049
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1079 trYTALVTLMTQYIKFAGDSLKRLEEEEIKRC----------KETSEHGAYSDLLQRqkatvlENSKLTGKISELERMVA 1148
Cdd:TIGR01612 1050 --HTSIYNIIDEIEKEIGKNIELLNKEILEEAeinitnfneiKEKLKHYNFDDFGKE------ENIKYADEINKIKDDIK 1121
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1149 ELKKQKSRVEEELPKVREAAEN---ELRKQQRNVEDISLQKIRAEsEAKQYRRELETIVREKEaaerelervrqltieae 1225
Cdd:TIGR01612 1122 NLDQKIDHHIKALEEIKKKSENyidEIKAQINDLEDVADKAISND-DPEEIEKKIENIVTKID----------------- 1183
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1226 aKRAAVEENLLNFRNQLEENTFTRRTLEdhlKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDL-AFQKQV 1304
Cdd:TIGR01612 1184 -KKKNIYDEIKKLLNEIAEIEKDKTSLE---EVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKS 1259
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1305 AEKQLKEKQKIELEARRKITEIQYTCRENALPVcpitqatscravtglQQEHDKQkAEELKQQVDELTAANRKaEQDMRE 1384
Cdd:TIGR01612 1260 PEIENEMGIEMDIKAEMETFNISHDDDKDHHII---------------SKKHDEN-ISDIREKSLKIIEDFSE-ESDIND 1322
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1385 LTYEL--NALQLEKTSSEekarlLKDKLDETNNTLRCLKLELERKDQAE-KGYSQQLRELGRQLNQTTGKAEEAmqeasd 1461
Cdd:TIGR01612 1323 IKKELqkNLLDAQKHNSD-----INLYLNEIANIYNILKLNKIKKIIDEvKEYTKEIEENNKNIKDELDKSEKL------ 1391
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1462 LKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHS-FRDEKE--------LERLQICQRKSDH-LK 1531
Cdd:TIGR01612 1392 IKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTyFKNADEnnenvlllFKNIEMADNKSQHiLK 1471
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1532 EQFEKSHEQLLQNIKAEKENNDKIQRLNEE-------LEKSNECAEMLKQKVEEL-------------TRQNNETKLMMQ 1591
Cdd:TIGR01612 1472 IKKDNATNDHDFNINELKEHIDKSKGCKDEadknakaIEKNKELFEQYKKDVTELlnkysalaiknkfAKTKKDSEIIIK 1551
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1592 RIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNehlhKQTKTEQDFQRKIKCLEEDLAKsqnlVSEFKQKcdqqn 1671
Cdd:TIGR01612 1552 EIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKND----KSNKAAIDIQLSLENFENKFLK----ISDIKKK----- 1618
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1672 iiIQNTKKEVRNLnaelnaskeEKRRGEQKVQLQQAQVQELNNRLKKVQDelHLKTIEEQmthrkmvlfqeesgkfKQSA 1751
Cdd:TIGR01612 1619 --INDCLKETESI---------EKKISSFSIDSQDTELKENGDNLNSLQE--FLESLKDQ----------------KKNI 1669
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1752 EEFRKKMEKLmeskvitendisgirldfvslqqensraqenaklcETNIKELERQLQQYREQMQQGqhmeanhyqKCQKL 1831
Cdd:TIGR01612 1670 EDKKKELDEL-----------------------------------DSEIEKIEIDVDQHKKNYEIG---------IIEKI 1705
|
1290 1300
....*....|....*....|...
gi 4502443 1832 EDELIAQKREVENLKQKMDQQIK 1854
Cdd:TIGR01612 1706 KEIAIANKEEIESIKELIEPTIE 1728
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1136-1455 |
3.95e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.08 E-value: 3.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1136 LTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRE--------LETIVREK 1207
Cdd:COG4913 615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELErldassddLAALEEQL 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1208 EAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENtftRRTLEDHLKRKDLSLN-DLEQQKNKLMEELRRKRdneee 1286
Cdd:COG4913 695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL---QDRLEAAEDLARLELRaLLEERFAAALGDAVERE----- 766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1287 llklikqMEKDLAFQKQVAEKQLKEKQKielEARRKITEIQytcreNALPVCPITQATSCRAVTGLQQEHDKQKAEELKQ 1366
Cdd:COG4913 767 -------LRENLEERIDALRARLNRAEE---ELERAMRAFN-----REWPAETADLDADLESLPEYLALLDRLEEDGLPE 831
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1367 QVDELTAA-NRKAEQDMRELTYELnalqlektssEEKARLLKDKLDETNNTL--------RCLKLELE-RKDQAEKGYSQ 1436
Cdd:COG4913 832 YEERFKELlNENSIEFVADLLSKL----------RRAIREIKERIDPLNDSLkripfgpgRYLRLEARpRPDPEVREFRQ 901
|
330
....*....|....*....
gi 4502443 1437 QLRELGRQLNQTTGKAEEA 1455
Cdd:COG4913 902 ELRAVTSGASLFDEELSEA 920
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1359-1584 |
4.48e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.69 E-value: 4.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1359 QKAEELKQQVDELTAAN------RKAEQDMRELTYELNALQLEKtsSEEKARLLKDKLDETNNTLRCLKLELERKDQAEK 1432
Cdd:COG4913 242 EALEDAREQIELLEPIRelaeryAAARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELARLEAELERLEARLD 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1433 GYSQQLRELGRQLNQTTGKaeeamqeasdlkkikrnyqlELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSfr 1512
Cdd:COG4913 320 ALREELDELEAQIRGNGGD--------------------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPA-- 377
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4502443 1513 DEKELERLqicQRKSDHLKEQFEKSHEQLLQnikAEKENNDKIQRLNEELEKsnecaemLKQKVEELTRQNN 1584
Cdd:COG4913 378 SAEEFAAL---RAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRE-------LEAEIASLERRKS 436
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1117-1723 |
5.74e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.57 E-value: 5.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1117 GAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVR---EAAENELRKQQRNVEDISLQKIRAES-- 1191
Cdd:pfam01576 398 QAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSsllNEAEGKNIKLSKDVSSLESQLQDTQEll 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1192 -EAKQYRRELETIVREKEAAERELErvRQLTIEAEAKRAA------VEENLLNFRNQLEENTFTRRTLEDHLKR------ 1258
Cdd:pfam01576 478 qEETRQKLNLSTRLRQLEDERNSLQ--EQLEEEEEAKRNVerqlstLQAQLSDMKKKLEEDAGTLEALEEGKKRlqrele 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1259 --------KDLSLNDLEQQKNKLMEELR-------RKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKI 1323
Cdd:pfam01576 556 altqqleeKAAAYDKLEKTKNRLQQELDdllvdldHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKE 635
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1324 TEIQYTCRenALPVCPITQATSCRAVTGLQQEHDK--QKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEE 1401
Cdd:pfam01576 636 TRALSLAR--ALEEALEAKEELERTNKQLRAEMEDlvSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATED 713
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1402 -KARLlkdkldETNntLRCLKLELERKDQA--EKGySQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH 1478
Cdd:pfam01576 714 aKLRL------EVN--MQALKAQFERDLQArdEQG-EEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEA 784
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1479 E-----KGK----------------LQREVD--RITRAHAVA-----EKNIQHLnsqihsfrdEKELERLQICQRKSDHL 1530
Cdd:pfam01576 785 QidaanKGReeavkqlkklqaqmkdLQRELEeaRASRDEILAqskesEKKLKNL---------EAELLQLQEDLAASERA 855
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1531 KEQFEKSHEQLLQNIKAEKENN-----------DKIQRLNEELEKSNECAEMLKQKVEELTRQNNEtklMMQRIQAEsen 1599
Cdd:pfam01576 856 RRQAQQERDELADEIASGASGKsalqdekrrleARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ---LTTELAAE--- 929
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1600 ivlekQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEqdFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKK 1679
Cdd:pfam01576 930 -----RSTSQKSESARQQLERQNKELKAKLQEMEGTVKSK--FKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEK 1002
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 4502443 1680 EVRNLnaeLNASKEEKRRGEQkvqlQQAQVQELNNRLKKVQDEL 1723
Cdd:pfam01576 1003 KLKEV---LLQVEDERRHADQ----YKDQAEKGNSRMKQLKRQL 1039
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1358-1875 |
7.53e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.97 E-value: 7.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1358 KQKAEELKQQVDELTAANrKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQ 1437
Cdd:TIGR00618 159 KAKSKEKKELLMNLFPLD-QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQ 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1438 LRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQlELESLNHEKGKLQREVDRITRAHAVAE--KNIQHLNSQ---IHSFR 1512
Cdd:TIGR00618 238 TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIE-ELRAQEAVLEETQERINRARKAAPLAAhiKAVTQIEQQaqrIHTEL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1513 DEKELERLQICQRKSDHLKEQFEKSHEQLLQNikaekenndKIQRLNEELEKSNECAEMLKqkvEELTRQNNETklmmQR 1592
Cdd:TIGR00618 317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQ---------TLHSQEIHIRDAHEVATSIR---EISCQQHTLT----QH 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1593 IQAESENIVLEKQTIQQRCEALkiqadgfkDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQnlvsefkQKCDQQNI 1672
Cdd:TIGR00618 381 IHTLQQQKTTLTQKLQSLCKEL--------DILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQ-------RYAELCAA 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1673 IIQNTKKEVRNLNAELNASKEEKRrgEQKVQLQQAQVQELNNRLKKvqdELHLKTIEEQmthrkmvlfQEESGKFKQSAE 1752
Cdd:TIGR00618 446 AITCTAQCEKLEKIHLQESAQSLK--EREQQLQTKEQIHLQETRKK---AVVLARLLEL---------QEEPCPLCGSCI 511
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1753 EFRKKMEKLMESKVITENDISGIrldfvslqQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLE 1832
Cdd:TIGR00618 512 HPNPARQDIDNPGPLTRRMQRGE--------QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSK 583
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 4502443 1833 DELIAQKREVENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAKD 1875
Cdd:TIGR00618 584 EDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
785-1851 |
8.04e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 55.06 E-value: 8.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 785 KLKKELERLKDDLGTITNKCEEFFSQAAASSS----VPTLRSELNVVLQNMnqvySMSSTYIDKLKTVNLVLKNTQAaea 860
Cdd:TIGR01612 562 EIKKELEEENEDSIHLEKEIKDLFDKYLEIDDeiiyINKLKLELKEKIKNI----SDKNEYIKKAIDLKKIIENNNA--- 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 861 lvklyetkLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFhalEDELQKakaISDEMFKTYKERDLDFDWHKEKADQ 940
Cdd:TIGR01612 635 --------YIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIY---EDDIDA---LYNELSSIVKENAIDNTEDKAKLDD 700
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 941 LVERWQNVHVQIDNRlrDLEGIGKSLKYYRDTYHPLDDWIqqVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQS 1020
Cdd:TIGR01612 701 LKSKIDKEYDKIQNM--ETATVELHLSNIENKKNELLDII--VEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAK 776
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1021 KMDECQKYAEQYSATVKDYELQTMtyramVDSQQKSPVKRRRMQSSadliiqefmdlrtRYTALVTLMTQYIKFAGDSLK 1100
Cdd:TIGR01612 777 EKDELNKYKSKISEIKNHYNDQIN-----IDNIKDEDAKQNYDKSK-------------EYIKTISIKEDEIFKIINEMK 838
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1101 RLEEEEIKR----------CKET--SEHGAYSDLLQRQKATVLEN--SKLTGKISELERMVAELKKQksrVEEELPKVre 1166
Cdd:TIGR01612 839 FMKDDFLNKvdkfinfennCKEKidSEHEQFAELTNKIKAEISDDklNDYEKKFNDSKSLINEINKS---IEEEYQNI-- 913
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1167 aaeNELRKQqrnveDISLQKIRAESEAKQYRRELETIVREKeaAERELERVRqltieaeakraavEENLL--NFRNQLEe 1244
Cdd:TIGR01612 914 ---NTLKKV-----DEYIKICENTKESIEKFHNKQNILKEI--LNKNIDTIK-------------ESNLIekSYKDKFD- 969
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1245 NTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDN-----EEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEA 1319
Cdd:TIGR01612 970 NTLIDKINELDKAFKDASLNDYEAKNNELIKYFNDLKANlgknkENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAI 1049
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1320 RRKI-------------------TEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEE----------LKQQVD- 1369
Cdd:TIGR01612 1050 HTSIyniideiekeigkniellnKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENIKYADEinkikddiknLDQKIDh 1129
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1370 ---ELTAANRKAEQDMRELTYELNALQ--LEKTSS-------EEKARLLKDKLDETNNTLRCLKLELERKDQAEK----- 1432
Cdd:TIGR01612 1130 hikALEEIKKKSENYIDEIKAQINDLEdvADKAISnddpeeiEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKdktsl 1209
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1433 --------GYSQQLRELG-RQLNQTTGKAE---EAMQE-ASDLKKIKRNYQlELESLNHEKGKLQREVDRITRAHAVAEK 1499
Cdd:TIGR01612 1210 eevkginlSYGKNLGKLFlEKIDEEKKKSEhmiKAMEAyIEDLDEIKEKSP-EIENEMGIEMDIKAEMETFNISHDDDKD 1288
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1500 niQHLNSQIH--SFRD--EKELERLQICQRKSD--HLKEQFEKSHeqllqnIKAEKENNDKIQRLNE--------ELEKS 1565
Cdd:TIGR01612 1289 --HHIISKKHdeNISDirEKSLKIIEDFSEESDinDIKKELQKNL------LDAQKHNSDINLYLNEianiynilKLNKI 1360
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1566 NECAEMLKQKVEELTRQNNETKLMMQR----IQAESENIVLE--KQTIQQRCEALKIQaDGFKDQLRSTNEHLHKQTKTE 1639
Cdd:TIGR01612 1361 KKIIDEVKEYTKEIEENNKNIKDELDKseklIKKIKDDINLEecKSKIESTLDDKDID-ECIKKIKELKNHILSEESNID 1439
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1640 QDFQRK----------IKCLEEDLAKSQNL---------------VSEFKQKCDQQNIIIQNTKKEVRNLnaELNASKEE 1694
Cdd:TIGR01612 1440 TYFKNAdennenvlllFKNIEMADNKSQHIlkikkdnatndhdfnINELKEHIDKSKGCKDEADKNAKAI--EKNKELFE 1517
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1695 KRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLfqeESGKFKQSAEEFRKkmEKLMESKVITENDIS- 1773
Cdd:TIGR01612 1518 QYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFIL---EAEKSEQKIKEIKK--EKFRIEDDAAKNDKSn 1592
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1774 ----GIRLDFVSLQQE-----NSRAQENAKLCETniKELERQLQQYREQMQQGQHME-ANHYQKCQKLEDELIAQKREVE 1843
Cdd:TIGR01612 1593 kaaiDIQLSLENFENKflkisDIKKKINDCLKET--ESIEKKISSFSIDSQDTELKEnGDNLNSLQEFLESLKDQKKNIE 1670
|
....*...
gi 4502443 1844 NLKQKMDQ 1851
Cdd:TIGR01612 1671 DKKKELDE 1678
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
282-373 |
8.73e-07 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 49.25 E-value: 8.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 282 VQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTA---PLKLTYAEKLHRLESQY 358
Cdd:smart00150 7 ADELEAWLEEKEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEeghPDAEEIEERLEELNERW 86
|
90
....*....|....*
gi 4502443 359 AKLLNTSRNQERHLD 373
Cdd:smart00150 87 EELKELAEERRQKLE 101
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1163-1615 |
1.13e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 1.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1163 KVREAAENELRKQQRNVEdISLQKIRAES----EAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLlnf 1238
Cdd:COG4717 50 RLEKEADELFKPQGRKPE-LNLKELKELEeelkEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL--- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1239 rnQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKekqkielE 1318
Cdd:COG4717 126 --QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ-------D 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1319 ARRKITEIQytcrenalpvcpitqatscravtglqqehdkQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTS 1398
Cdd:COG4717 197 LAEELEELQ-------------------------------QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1399 SEEKARLL------------KDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIK 1466
Cdd:COG4717 246 KEARLLLLiaaallallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1467 RNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLnsQIHSFRDEKElerlQICQRKSDHLKEQFEKSHEQLLQNIK 1546
Cdd:COG4717 326 AALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIA----ALLAEAGVEDEEELRAALEQAEEYQE 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1547 AEKENNDKIQRLNEELEKSNECAEMLKQkvEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALK 1615
Cdd:COG4717 400 LKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELREELAELEAELEQLE 466
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1289-1619 |
1.24e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.97 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1289 KLIKQMEKDLAFQKQVAEK--QLKEKQKIELEARRKITEIQyTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQ 1366
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERlrQEKEEKAREVERRRKLEEAE-KARQAEMDRQAAIYAEQERMAMERERELERIRQEERKR 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1367 QVDELtaanRKAEQDMR-ELTYELNALQLEKTSSEEKARllkdkldetnntlrcLKLELERKDQ-AEKGYSQQLRELGRQ 1444
Cdd:pfam17380 361 ELERI----RQEEIAMEiSRMRELERLQMERQQKNERVR---------------QELEAARKVKiLEEERQRKIQQQKVE 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1445 LNQTTGKAEEAMQEasDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQ 1524
Cdd:pfam17380 422 MEQIRAEQEEARQR--EVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1525 rksdHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEK 1604
Cdd:pfam17380 500 ----ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERER 575
|
330
....*....|....*
gi 4502443 1605 QTIQQRCEALKIQAD 1619
Cdd:pfam17380 576 EMMRQIVESEKARAE 590
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1435-1658 |
1.39e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 SQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRde 1514
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR-- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1515 KELERLQicQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQR---LNEELEKSNECAEMLKQKVEELTRQNNETKLMMQ 1591
Cdd:COG4942 97 AELEAQK--EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1592 RIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQN 1658
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1605-1864 |
1.42e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1605 QTIQQRCEALKIQAdgFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKcdqqniiIQNTKKEVRNL 1684
Cdd:COG1196 216 RELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE-------LEELELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1685 NAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMES 1764
Cdd:COG1196 287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1765 KVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQ-------QYREQMQQGQHMEANHYQKCQKLEDELIA 1837
Cdd:COG1196 367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEallerleRLEEELEELEEALAELEEEEEEEEEALEE 446
|
250 260
....*....|....*....|....*..
gi 4502443 1838 QKREVENLKQKMDQQIKEHEHQLVLLQ 1864
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAA 473
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1149-1665 |
1.49e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.89 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1149 ELKKQKSRVEE-ELPKVREAAENELRKQQRNVEDISLQKIRAE----------SEAKQYRRELETIvrekeaaERELERV 1217
Cdd:PRK02224 191 QLKAQIEEKEEkDLHERLNGLESELAELDEEIERYEEQREQARetrdeadevlEEHEERREELETL-------EAEIEDL 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1218 RQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKD 1297
Cdd:PRK02224 264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1298 lafqkqvAEKQLKEKQKIELEARRKiteiqytcRENALPVcpITQATSCRAVTGLQQEhdkqKAEELKQQVDELTAANRK 1377
Cdd:PRK02224 344 -------AESLREDADDLEERAEEL--------REEAAEL--ESELEEAREAVEDRRE----EIEELEEEIEELRERFGD 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1378 AEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLEL----------------------ERKDQAEKgys 1435
Cdd:PRK02224 403 APVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgqpvegsphvetieEDRERVEE--- 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1436 qqLRELGRQLNQTTGKAEEAMQEASDLKKIKRnyqlELESLnheKGKLQREVDRITRAHAVAEKNiqhlNSQIHSFRDEK 1515
Cdd:PRK02224 480 --LEAELEDLEEEVEEVEERLERAEDLVEAED----RIERL---EERREDLEELIAERRETIEEK----RERAEELRERA 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1516 -ELERLQICQRKS-DHLKEQFEKSHEQL------LQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETK 1587
Cdd:PRK02224 547 aELEAEAEEKREAaAEAEEEAEEAREEVaelnskLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERR 626
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1588 lmmQRIQAESENIV-LEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQ 1665
Cdd:PRK02224 627 ---ERLAEKRERKReLEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREA 702
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1528-1723 |
1.58e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1528 DHLKEQFE--KSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLmmQRIQAESENIVLEKQ 1605
Cdd:COG4913 228 DALVEHFDdlERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL--ELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1606 TIQQRCEALKIQADGFKDQLRSTNEHLHKQ-TKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKE---- 1680
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEfaal 385
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 4502443 1681 VRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDEL 1723
Cdd:COG4913 386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1382-1855 |
1.96e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1382 MRELTYELNALQlekTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEkgysQQLRELGRQLNQTTGKAEEAMQEASD 1461
Cdd:COG4717 48 LERLEKEADELF---KPQGRKPELNLKELKELEEELKEAEEKEEEYAELQ----EELEELEEELEELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1462 LKKIKRNYQL--ELESLNHEKGKLQREVDRITRAHAV---AEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLkEQFEK 1536
Cdd:COG4717 121 LEKLLQLLPLyqELEALEAELAELPERLEELEERLEElreLEEELEELEAELAELQEELEELLEQLSLATEEEL-QDLAE 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1537 SHEQLLQnikaekenndKIQRLNEELEKsnecaemLKQKVEELTRQNNETKLMMQRIQAESEnivLEKQTIQQRCEALKI 1616
Cdd:COG4717 200 ELEELQQ----------RLAELEEELEE-------AQEELEELEEELEQLENELEAAALEER---LKEARLLLLIAAALL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1617 QADGFKDQLRSTNEHLHKQTKTEQDFqrkIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKR 1696
Cdd:COG4717 260 ALLGLGGSLLSLILTIAGVLFLVLGL---LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSP 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1697 RGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHrkmvLFQEESGKfkqSAEEFRKKMEKLMESKVITEndisgiR 1776
Cdd:COG4717 337 EELLELLDRIEELQELLREAEELEEELQLEELEQEIAA----LLAEAGVE---DEEELRAALEQAEEYQELKE------E 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1777 LDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLE---------DELIAQKREVENLKQ 1847
Cdd:COG4717 404 LEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEaeleqleedGELAELLQELEELKA 483
|
....*...
gi 4502443 1848 KMDQQIKE 1855
Cdd:COG4717 484 ELRELAEE 491
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1462-1860 |
3.17e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.76 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1462 LKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRD-EKELERLQICQRKSDHLKEQFEKSHEQ 1540
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPElREELEKLEKEVKELEELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1541 LLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMqRIQAESENIVLEKQTIQQRCEALKIQADG 1620
Cdd:PRK03918 247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYI-KLSEFYEEYLDELREIEKRLSRLEEEING 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1621 FKDQLR---STNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRR 1697
Cdd:PRK03918 326 IEERIKeleEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEE 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1698 GEQKVQLQQAQVQELNNRLKKVQDELHL---------KTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVIT 1768
Cdd:PRK03918 406 EISKITARIGELKKEIKELKKAIEELKKakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1769 ENDISGIRlDFVSLQQ--ENSRAQENaKLCETNIKELERQLQQYREQMQQGQHMEAN--HYQKCQKLEDELIAQKREVEN 1844
Cdd:PRK03918 486 EKVLKKES-ELIKLKElaEQLKELEE-KLKKYNLEELEKKAEEYEKLKEKLIKLKGEikSLKKELEKLEELKKKLAELEK 563
|
410
....*....|....*.
gi 4502443 1845 LKQKMDQQIKEHEHQL 1860
Cdd:PRK03918 564 KLDELEEELAELLKEL 579
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1399-1814 |
3.21e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.13 E-value: 3.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1399 SEEKArlLKDKLDETNNTLRCLK-LELERKDQAEKGYSQQLRELGRQLNQTTGK----------AEEAMQEASdlKKIKR 1467
Cdd:TIGR00606 166 SEGKA--LKQKFDEIFSATRYIKaLETLRQVRQTQGQKVQEHQMELKYLKQYKEkaceirdqitSKEAQLESS--REIVK 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1468 NYQLELESLNHEKGKLQR------EVDRITRAHAVAEKNIQHLNSQIhsfrdekELERLQICQRKSDHLKEQFEKSHEQL 1541
Cdd:TIGR00606 242 SYENELDPLKNRLKEIEHnlskimKLDNEIKALKSRKKQMEKDNSEL-------ELKMEKVFQGTDEQLNDLYHNHQRTV 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1542 lqnikaeKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCE--------- 1612
Cdd:TIGR00606 315 -------REKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLEldgfergpf 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1613 -------ALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLN 1685
Cdd:TIGR00606 388 serqiknFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1686 ----------------------AELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDEL-HLKTIEEQM---THRKMVL 1739
Cdd:TIGR00606 468 gssdrileldqelrkaerelskAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLnHHTTTRTQMemlTKDKMDK 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1740 FQEESGKFKQSAEEF---------RKKMEKLMESKvitENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQY 1810
Cdd:TIGR00606 548 DEQIRKIKSRHSDELtsllgyfpnKKQLEDWLHSK---SKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY 624
|
....
gi 4502443 1811 REQM 1814
Cdd:TIGR00606 625 EDKL 628
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
1359-1852 |
3.35e-06 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 52.83 E-value: 3.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1359 QKAEELKQQVDELtaanRKAEQDMReltyelnalQLEKTSSEEKARLlkdkldetnnTLRCLKLE-LERKDQAEKGYSQQ 1437
Cdd:pfam07111 63 QQAELISRQLQEL----RRLEEEVR---------LLRETSLQQKMRL----------EAQAMELDaLAVAEKAGQAEAEG 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1438 LRELGRQLNQTTGKAEEAMQEasDLKKIKRNYQLELESLNHEKgklQREVDRITRAHAVAEKNIQHLNSqihsfRDEKEL 1517
Cdd:pfam07111 120 LRAALAGAEMVRKNLEEGSQR--ELEEIQRLHQEQLSSLTQAH---EEALSSLTSKAEGLEKSLNSLET-----KRAGEA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1518 ERLQICQRKSDHLKEQFEKSHEQL------LQNIK--AEKENNDKIQRLNEELEKsNECAEMLKQKVEELTRQNNETKLM 1589
Cdd:pfam07111 190 KQLAEAQKEAELLRKQLSKTQEELeaqvtlVESLRkyVGEQVPPEVHSQTWELER-QELLDTMQHLQEDRADLQATVELL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1590 MQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEH-------LHKQTKTeQDFQRK--IKCLEEDLAKSQNLV 1660
Cdd:pfam07111 269 QVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKKCRSLLNRwrekvfaLMVQLKA-QDLEHRdsVKQLRGQVAELQEQV 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1661 SEFKQKCDQQNIIIQNTKKEV-------RNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELH--------- 1724
Cdd:pfam07111 348 TSQSQEQAILQRALQDKAAEVevermsaKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLEttmtrveqa 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1725 -----------------LKTIEEQMThRKMVLFQ--EESGKFKQSAEEFRKKMEKLMESKVITENDISG-IRLDFVSLQQ 1784
Cdd:pfam07111 428 varipslsnrlsyavrkVHTIKGLMA-RKVALAQlrQESCPPPPPAPPVDADLSLELEQLREERNRLDAeLQLSAHLIQQ 506
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502443 1785 ENSRAQENAKLCETNIKELERQLQQyreQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQ 1852
Cdd:pfam07111 507 EVGRAREQGEAERQQLSEVAQQLEQ---ELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQ 571
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1363-1722 |
3.54e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 52.20 E-value: 3.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1363 ELKQQVDELTAANRKAEQDMRELTYELNALQLEKTS-SEEKARLLKDKLDetnNTLRCLKLElerkdQAEKGYSQQLREL 1441
Cdd:pfam07888 77 ELESRVAELKEELRQSREKHEELEEKYKELSASSEElSEEKDALLAQRAA---HEARIRELE-----EDIKTLTQRVLER 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1442 GRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDekeleRLQ 1521
Cdd:pfam07888 149 ETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQ-----KLT 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1522 ICQRKsdhlkeqfEKSHEQLLQNIKAekenndkiqrLNEELEKSNECAEMLKQKVEELTRQNNET--KLMMQRIQAESEN 1599
Cdd:pfam07888 224 TAHRK--------EAENEALLEELRS----------LQERLNASERKVEGLGEELSSMAAQRDRTqaELHQARLQAAQLT 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1600 IVLEKQTIQQRCEalKIQADGFKDQLRSTNEHLH-KQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTK 1678
Cdd:pfam07888 286 LQLADASLALREG--RARWAQERETLQQSAEADKdRIEKLSAELQRLEERLQEERMEREKLEVELGREKDCNRVQLSESR 363
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 4502443 1679 KEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDE 1722
Cdd:pfam07888 364 RELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVADA 407
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
981-1325 |
4.01e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 981 QQVETTQRKIQE-NQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEqysATVKDYELQTMTYRAMVDSQQKSPVK 1059
Cdd:PTZ00121 1457 KKAEEAKKKAEEaKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE---AKKKADEAKKAEEAKKADEAKKAEEA 1533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1060 RRRMQSSADLIIQEFMDLR----TRYTALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSK 1135
Cdd:PTZ00121 1534 KKADEAKKAEEKKKADELKkaeeLKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK 1613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1136 LtgkiSELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELE 1215
Cdd:PTZ00121 1614 K----AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1216 RVRQLTIEAEAKRAAveENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQME 1295
Cdd:PTZ00121 1690 AAEALKKEAEEAKKA--EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767
|
330 340 350
....*....|....*....|....*....|
gi 4502443 1296 KDLAFQKQVAEKQLKEKQKIELEARRKITE 1325
Cdd:PTZ00121 1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
627-1772 |
5.31e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 52.36 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 627 NRIEQQYQNVLTlwHESHINMKSVVSWHYLINEIDRIRASNVASIKTmlpgehqQVLSNLQSRFEDFLEDSQESQVFSGS 706
Cdd:TIGR01612 1029 NDIEQKIEDANK--NIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNK-------EILEEAEINITNFNEIKEKLKHYNFD 1099
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 707 DITqleKEVNVckQYYQELLKSAEREEQEESVYNLYISEVRNIRLRLENCEDRLIRQIrtplerDDLhESVFRITEQEKL 786
Cdd:TIGR01612 1100 DFG---KEENI--KYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQI------NDL-EDVADKAISNDD 1167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 787 KKELERLKDDLGTITNKCEEFFSqaaasssvptlrsELNVVLQNMNQVySMSSTYIDKLKTVNLvlkntQAAEALVKLYE 866
Cdd:TIGR01612 1168 PEEIEKKIENIVTKIDKKKNIYD-------------EIKKLLNEIAEI-EKDKTSLEEVKGINL-----SYGKNLGKLFL 1228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 867 TKLCEEeaviadKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEM--FKTYKERDLDFDWHKEKADQLVER 944
Cdd:TIGR01612 1229 EKIDEE------KKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMetFNISHDDDKDHHIISKKHDENISD 1302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 945 WQNVHVQI---DNRLRDLEGIGKSLKYY------------------RDTYHPL-----DDWIQQVETTQRKIQenqpENS 998
Cdd:TIGR01612 1303 IREKSLKIiedFSEESDINDIKKELQKNlldaqkhnsdinlylneiANIYNILklnkiKKIIDEVKEYTKEIE----ENN 1378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 999 KTLATQLNQQKMLVSEIEmKQSKMDECQKYAEqysATVKDYELQtmtyramvDSQQKSPVKRRRMQSSADLIIQEFMDLR 1078
Cdd:TIGR01612 1379 KNIKDELDKSEKLIKKIK-DDINLEECKSKIE---STLDDKDID--------ECIKKIKELKNHILSEESNIDTYFKNAD 1446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1079 tRYTALVTLMTQYIKFAGDSLKRLeeEEIKRCKETSEHG-------AYSDLLQRQKATVLENSKLTGKISELermvaeLK 1151
Cdd:TIGR01612 1447 -ENNENVLLLFKNIEMADNKSQHI--LKIKKDNATNDHDfninelkEHIDKSKGCKDEADKNAKAIEKNKEL------FE 1517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1152 KQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRaesEAKQyrreleTIVREKEAAERELERVR--QLTIEAEA--- 1226
Cdd:TIGR01612 1518 QYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIK---DAHK------KFILEAEKSEQKIKEIKkeKFRIEDDAakn 1588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1227 ---KRAA--VEENLLNFRNQLEENTFTRRTLEDHLK-----RKDLSLNDLEQQKNKLmEELRRKRDNEEELLKLIKQMEK 1296
Cdd:TIGR01612 1589 dksNKAAidIQLSLENFENKFLKISDIKKKINDCLKetesiEKKISSFSIDSQDTEL-KENGDNLNSLQEFLESLKDQKK 1667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1297 DLAFQKQVAEKQLKEKQKIELEA--RRKITEIQytcrenalpvcpITQATSCRAVTglqqehDKQKAEELKQQVdeltaa 1374
Cdd:TIGR01612 1668 NIEDKKKELDELDSEIEKIEIDVdqHKKNYEIG------------IIEKIKEIAIA------NKEEIESIKELI------ 1723
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1375 nrkaEQDMRELTYELNALQLEKTSSEEkarllkdKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEE 1454
Cdd:TIGR01612 1724 ----EPTIENLISSFNTNDLEGIDPNE-------KLEEYNTEIGDIYEEFIELYNIIAGCLETVSKEPITYDEIKNTRIN 1792
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1455 AMQEASDLKKIKRNYQLELES---------LNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFR---DEKELerLQI 1522
Cdd:TIGR01612 1793 AQNEFLKIIEIEKKSKSYLDDieakefdriINHFKKKLDHVNDKFTKEYSKINEGFDDISKSIENVKnstDENLL--FDI 1870
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1523 CQRKSDHLKEQFEKSH-------EQLLQNI-KAEKENNDKIQrlneelekSNECAEMLKQ-KVEELTRQNNETKLMMQRI 1593
Cdd:TIGR01612 1871 LNKTKDAYAGIIGKKYysykdeaEKIFINIsKLANSINIQIQ--------NNSGIDLFDNiNIAILSSLDSEKEDTLKFI 1942
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1594 ---QAESENIVLEKQTIQQRCEALKIQADGFKDQ-----LRSTNEHLH---KQTKTEQDFQRKIKCLEEDLAKSQNLV-- 1660
Cdd:TIGR01612 1943 pspEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEqdtlnIIFENQQLYekiQASNELKDTLSDLKYKKEKILNDVKLLlh 2022
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1661 --SEFKQ-KCDQQN--IIIQNTKKEvrNLNAELNASKEEKRRGEQKVQLqQAQVQELNNRLKKVQDELHLKTIEEQMTHR 1735
Cdd:TIGR01612 2023 kfDELNKlSCDSQNydTILELSKQD--KIKEKIDNYEKEKEKFGIDFDV-KAMEEKFDNDIKDIEKFENNYKHSEKDNHD 2099
|
1210 1220 1230 1240
....*....|....*....|....*....|....*....|...
gi 4502443 1736 kmvlFQEESGKFKQSAEEFRKKME------KLMESKVITENDI 1772
Cdd:TIGR01612 2100 ----FSEEKDNIIQSKKKLKELTEafnteiKIIEDKIIEKNDL 2138
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2553-2586 |
5.80e-06 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 45.17 E-value: 5.80e-06
10 20 30
....*....|....*....|....*....|....
gi 4502443 2553 IRCLEFQYLTGGLIEPQVHSRLSIEEALQVGIID 2586
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1139-1591 |
7.69e-06 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 51.38 E-value: 7.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1139 KISELERMVAELKKQKsrVEEELPKVREA-----AENELRKQQRNVEDISLQKI--------RAESEAKQYR-----REL 1200
Cdd:PRK04778 30 RIDELEERKQELENLP--VNDELEKVKKLnltgqSEEKFEEWRQKWDEIVTNSLpdieeqlfEAEELNDKFRfrkakHEI 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1201 ETIVREKEAAERELERVR----QLTIEAEAKRAAVEENLLNF---RNQLEENTFTRRTLEDHLKRKdlsLNDLEQQKNKl 1273
Cdd:PRK04778 108 NEIESLLDLIEEDIEQILeelqELLESEEKNREEVEQLKDLYrelRKSLLANRFSFGPALDELEKQ---LENLEEEFSQ- 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1274 MEELRRKRDNE---EELLKLIKQMEkdlAFQKQVAE-KQLKEKQKIELEARrkITEIQYTCRE-----NALPVCPITQAt 1344
Cdd:PRK04778 184 FVELTESGDYVearEILDQLEEELA---ALEQIMEEiPELLKELQTELPDQ--LQELKAGYRElveegYHLDHLDIEKE- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1345 scraVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELtYELnaLQLE---KTSSEEKARLLKDKLDETNNTLRCLK 1421
Cdd:PRK04778 258 ----IQDLKEQIDENLALLEELDLDEAEEKNEEIQERIDQL-YDI--LEREvkaRKYVEKNSDTLPDFLEHAKEQNKELK 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1422 LELERKDQA----------EKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRIT 1491
Cdd:PRK04778 331 EEIDRVKQSytlneselesVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEILKQLEEIEKEQEKLSEMLQGLR 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1492 RAHAVAEKNIQHLNSQIHSFRdeKELERLQICQRKSDHLKEQFEKSHE--QLLQNIKAEKENNDKIQRLneeLEKSNECA 1569
Cdd:PRK04778 411 KDELEAREKLERYRNKLHEIK--RYLEKSNLPGLPEDYLEMFFEVSDEieALAEELEEKPINMEAVNRL---LEEATEDV 485
|
490 500
....*....|....*....|..
gi 4502443 1570 EMLKQKVEELTRQNNETKLMMQ 1591
Cdd:PRK04778 486 ETLEEETEELVENATLTEQLIQ 507
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1134-1465 |
7.94e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.56 E-value: 7.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1134 SKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISL---------QKIR-AESEAKQYRRELETI 1203
Cdd:TIGR04523 338 SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesqindleSKIQnQEKLNQQKDEQIKKL 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1204 VREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDN 1283
Cdd:TIGR04523 418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1284 EEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCREnalpvcpITQATSCRAVTGLQQEHDK--QKA 1361
Cdd:TIGR04523 498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE-------LNKDDFELKKENLEKEIDEknKEI 570
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1362 EELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLREL 1441
Cdd:TIGR04523 571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQI 650
|
330 340
....*....|....*....|....
gi 4502443 1442 GRQLNQTTGKAEEAMQEASDLKKI 1465
Cdd:TIGR04523 651 KETIKEIRNKWPEIIKKIKESKTK 674
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1311-1859 |
9.86e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 9.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1311 EKQKIELEARRKITEIQYTCRENAlpvcpitqatscravTGLQQEHDKQKaeELKQQVDELTAANRKAEQDMREltyELN 1390
Cdd:pfam05557 17 EKKQMELEHKRARIELEKKASALK---------------RQLDRESDRNQ--ELQKRIRLLEKREAEAEEALRE---QAE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1391 ALQLEKTSSEEKARLLKDK---LDETNNTLRCLKlelerkdqaekgysqqlrelgrqlnqttgkaeeamQEASDLKKIKR 1467
Cdd:pfam05557 77 LNRLKKKYLEALNKKLNEKesqLADAREVISCLK-----------------------------------NELSELRRQIQ 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1468 NYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDE----KELERlQICQRKSDhlKEQFEKSHEQLLQ 1543
Cdd:pfam05557 122 RAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAeqriKELEF-EIQSQEQD--SEIVKNSKSELAR 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1544 NIKAEKEnndkIQRL---NEELEKSNECAEMLKQKVEELtrqnnETKL-MMQRIQAESENIVLEKQTIQQRCEALKiqad 1619
Cdd:pfam05557 199 IPELEKE----LERLrehNKHLNENIENKLLLKEEVEDL-----KRKLeREEKYREEAATLELEKEKLEQELQSWV---- 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1620 gfkdqlrstnehlhkqtKTEQDfqrkiKCLeeDLAKSQNLVSEFKQkCDQQNIiiqNTKKEVRNLNAELNASKEEKRRGE 1699
Cdd:pfam05557 266 -----------------KLAQD-----TGL--NLRSPEDLSRRIEQ-LQQREI---VLKEENSSLTSSARQLEKARRELE 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1700 QKVQLQQAQVQELNNRLKkvqdelHLKTIEEQMTHRKMVLFQEESGkFKQSAEEFRKKM------EKLMESKVITENDIS 1773
Cdd:pfam05557 318 QELAQYLKKIEDLNKKLK------RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELtmsnysPQLLERIEEAEDMTQ 390
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1774 GIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQG-QHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQ 1852
Cdd:pfam05557 391 KMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLAdPSYSKEEVDSLRRKLETLELERQRLREQKNELEME 470
|
....*..
gi 4502443 1853 IKEHEHQ 1859
Cdd:pfam05557 471 LERRCLQ 477
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1393-1736 |
1.11e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.89 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1393 QLEKTSSEEKARLLKDKLDETNntlrclklELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQle 1472
Cdd:pfam17380 289 QQEKFEKMEQERLRQEKEEKAR--------EVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEER-- 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1473 leslnhekgklQREVDRITRahavaekniQHLNSQIHSFRdekELERLQI-CQRKSDHLKEQFEKSHEQLLQ-------- 1543
Cdd:pfam17380 359 -----------KRELERIRQ---------EEIAMEISRMR---ELERLQMeRQQKNERVRQELEAARKVKILeeerqrki 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1544 --------NIKAEKEN--NDKIQRLNEELEKsnecaEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTiQQRCEA 1613
Cdd:pfam17380 416 qqqkvemeQIRAEQEEarQREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEK-RDRKRA 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1614 LKIQADGFKDQLRStnehlHKQTKTEQDFQRKIkcLEEDLAKSQNLVSEFKQKcdqqniiiqNTKKEVRNLNAELnaskE 1693
Cdd:pfam17380 490 EEQRRKILEKELEE-----RKQAMIEEERKRKL--LEKEMEERQKAIYEEERR---------REAEEERRKQQEM----E 549
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 4502443 1694 EKRRgeqkVQLQQAQVQELNNRLKKVQDELH-LKTIEEQMTHRK 1736
Cdd:pfam17380 550 ERRR----IQEQMRKATEERSRLEAMEREREmMRQIVESEKARA 589
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1184-1326 |
1.17e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.55 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1184 LQKIRAESEAKQYRRELETIVrekEAAERELERVRQLtIEAEAKraaveENLLNFRNQLEENTFTRRtleDHLKRKDLSL 1263
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRIL---EEAKKEAEAIKKE-ALLEAK-----EEIHKLRNEFEKELRERR---NELQKLEKRL 91
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4502443 1264 NDLEQQKNKLMEELRRKrdnEEELLKLikqmEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Cdd:PRK12704 92 LQKEENLDRKLELLEKR---EEELEKK----EKELEQKQQELEKKEEELEELIEEQLQELERI 147
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1264-1564 |
1.78e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 50.29 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1264 NDLEQQKNKLMEElRRKRDNEEELLKLIKQMEKDLAFQKQV-------AEKQLKEKQKIElearRKITEIQYTCREnalp 1336
Cdd:PLN02939 111 IDNEQQTNSKDGE-QLSDFQLEDLVGMIQNAEKNILLLNQArlqaledLEKILTEKEALQ----GKINILEMRLSE---- 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1337 vcpitqaTSCRAVTGLQQEHDKQKAEE-LKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNN 1415
Cdd:PLN02939 182 -------TDARIKLAAQEKIHVEILEEqLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAE 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1416 T-LRCLKLELERKdqaekGYSQQLRELGRQLNQttgkAEEAMQEASDLKkikrnYQLELESLNHEKGKLQREVDRITRAH 1494
Cdd:PLN02939 255 TeERVFKLEKERS-----LLDASLRELESKFIV----AQEDVSKLSPLQ-----YDCWWEKVENLQDLLDRATNQVEKAA 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1495 AVAEKNiQHLNSQIHSFRDEKE--------LERLQICQRKSDHLKEQFEKSHEQLLQNIK----AEKENNDKIQRLNEEL 1562
Cdd:PLN02939 321 LVLDQN-QDLRDKVDKLEASLKeanvskfsSYKVELLQQKLKLLEERLQASDHEIHSYIQlyqeSIKEFQDTLSKLKEES 399
|
..
gi 4502443 1563 EK 1564
Cdd:PLN02939 400 KK 401
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1436-1736 |
1.81e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.73 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1436 QQLRELGRQLNQttgKAEEAMQEASDLKKIKRNYQ-------------------LELESLNHEKGKLQREVDRIT----- 1491
Cdd:PRK04863 786 KRIEQLRAEREE---LAERYATLSFDVQKLQRLHQafsrfigshlavafeadpeAELRQLNRRRVELERALADHEsqeqq 862
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1492 -RAHAVAEKN----IQHLNSQIHSFRDEKELERLQICQRKSDHLKE--QFEKSH-------EQLLQNIKAEKENNDKIQR 1557
Cdd:PRK04863 863 qRSQLEQAKEglsaLNRLLPRLNLLADETLADRVEEIREQLDEAEEakRFVQQHgnalaqlEPIVSVLQSDPEQFEQLKQ 942
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1558 LNEELEKSNEcaeMLKQKVEELTRqnnetklMMQRIQ----AESENIVLEKQ----TIQQRCEALKIQADGFKDQLRSTN 1629
Cdd:PRK04863 943 DYQQAQQTQR---DAKQQAFALTE-------VVQRRAhfsyEDAAEMLAKNSdlneKLRQRLEQAEQERTRAREQLRQAQ 1012
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1630 EHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEvrNLNAELNASKEEKRRGEQKVQLQQAQV 1709
Cdd:PRK04863 1013 AQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARRD--ELHARLSANRSRRNQLEKQLTFCEAEM 1090
|
330 340
....*....|....*....|....*..
gi 4502443 1710 QELNNRLKKVQDELHlkTIEEQMTHRK 1736
Cdd:PRK04863 1091 DNLTKKLRKLERDYH--EMREQVVNAK 1115
|
|
| Tht1 |
pfam04163 |
Tht1-like nuclear fusion protein; |
1599-1875 |
1.96e-05 |
|
Tht1-like nuclear fusion protein;
Pssm-ID: 282073 Cd Length: 595 Bit Score: 50.21 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1599 NIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTktEQDFQRkikcLEEDLAKS-QNLVSEFKQKCDQQNIIIQNT 1677
Cdd:pfam04163 156 LLEFEKELIIELFLNITELQDQFGDDLDMKILHLMFQM--EQDFEN----FLDDLAQMfDKFDGEFNNATESNRIIIEND 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1678 KKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELhlktieeqmtHRKMVLFQEESGKFKQSAeefrkk 1757
Cdd:pfam04163 230 FKDFNFKVNDEIMGLVELENHEQEGMVLEKEIIEKIKQLKNEIDDI----------HHFFADFADELAGYKNDI------ 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1758 MEKLMESKVITENDIsgirldfvSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANhyQKCQKLEDELIA 1837
Cdd:pfam04163 294 IEKINDLKDDSENAI--------ALSAIGKYTSEFSAFMEKNIKDLIEMSEDSLKESVQRNIDFVN--SGFQELEDFSIG 363
|
250 260 270
....*....|....*....|....*....|....*....
gi 4502443 1838 QKREVENLKQKM-DQQIKEHEHqlvLLQCEIQKKSTAKD 1875
Cdd:pfam04163 364 LKEELGGLKKDLsEQQNLEAEE---ILQWKSDFLNILHD 399
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1432-1874 |
2.18e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.21 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1432 KGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSF 1511
Cdd:pfam10174 170 KGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNI 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1512 RD-EKELERLQ-----ICQRKSDHLKeQFE--KSHEQLLQNikaekenndKIQRLNEELEKSNECAEMLKQKVEELTRQN 1583
Cdd:pfam10174 250 RDlEDEVQMLKtngllHTEDREEEIK-QMEvyKSHSKFMKN---------KIDQLKQELSKKESELLALQTKLETLTNQN 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1584 NETKlmmQRIQAESENIVLEkqtiQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD---------------------- 1641
Cdd:pfam10174 320 SDCK---QHIEVLKESLTAK----EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDlteekstlageirdlkdmldvk 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1642 ------FQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELnASKEE--KRRGEQKVQLQQAQVQELN 1713
Cdd:pfam10174 393 erkinvLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEAL-SEKERiiERLKEQREREDRERLEELE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1714 NRLKKvqdelhLKTIEEQMTHRKMVLFQEESG--KFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQE 1791
Cdd:pfam10174 472 SLKKE------NKDLKEKVSALQPELTEKESSliDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHN 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1792 NAKLCETN------IKELERQLQQYREqmqqgqhmEANhyqKCQKLEDELIAQKREVENLKQKMDQQIKEHEhQLVLLQC 1865
Cdd:pfam10174 546 AEEAVRTNpeindrIRLLEQEVARYKE--------ESG---KAQAEVERLLGILREVENEKNDKDKKIAELE-SLTLRQM 613
|
....*....
gi 4502443 1866 EIQKKSTAK 1874
Cdd:pfam10174 614 KEQNKKVAN 622
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1514-1723 |
2.33e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1514 EKELERLQICQRKSDHLKEQFEKSHEQLLQNIKaekENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRI 1593
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLA---ALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1594 QAESENIVLEKQTIQQRCE-ALKIQADGFKDQLRST------NEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQK 1666
Cdd:COG4942 103 KEELAELLRALYRLGRQPPlALLLSPEDFLDAVRRLqylkylAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1667 CDQQNIIIQNTKKEVRNLNAELNASKEEKRrgeQKVQLQQAQVQELNNRLKKVQDEL 1723
Cdd:COG4942 183 LEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEA 236
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1519-1876 |
2.45e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.51 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1519 RLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKS----NECAEMLKQKVEELTRQNNETKLMMQRIQ 1594
Cdd:pfam07888 35 RLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRvaelKEELRQSREKHEELEEKYKELSASSEELS 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1595 AESENIVLEKQTIQQRCEALK--IQADGFKDQLRSTNEHLHKQTKTEQDFQRKikcleEDLAKSQNLVSEFKQkcdqqni 1672
Cdd:pfam07888 115 EEKDALLAQRAAHEARIRELEedIKTLTQRVLERETELERMKERAKKAGAQRK-----EEEAERKQLQAKLQQ------- 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1673 iiqnTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLkkvqDELHLKTIEEQMTHRKMVLFQEESGKFKQSAE 1752
Cdd:pfam07888 183 ----TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKL----TTAHRKEAENEALLEELRSLQERLNASERKVE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1753 EFRKKMEKLMESKVITENDISGIRLDfvslqqensRAQENAKLCETNI--KELERQLQQYREQMQQGqhMEANHyQKCQK 1830
Cdd:pfam07888 255 GLGEELSSMAAQRDRTQAELHQARLQ---------AAQLTLQLADASLalREGRARWAQERETLQQS--AEADK-DRIEK 322
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 4502443 1831 LEDELiaqkrevenlkQKMDQQIKEHEHQLVLLQCEIQKKstaKDC 1876
Cdd:pfam07888 323 LSAEL-----------QRLEERLQEERMEREKLEVELGRE---KDC 354
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1113-1846 |
2.54e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.95 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1113 TSEHGAYSDLLQRqkatVLENSKLTGKIselERMVAELKKQKSRVEEELPKVREAAENELRKQQRnvedislqKIRAESE 1192
Cdd:COG3096 326 EQDYQAASDHLNL----VQTALRQQEKI---ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEAR--------LEAAEEE 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1193 AKQ-------YRRELETIVREKEA---AERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLS 1262
Cdd:COG3096 391 VDSlksqladYQQALDVQQTRAIQyqqAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAA 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1263 LNDLE-------------------QQKNKLMEELRRKR---DNEEELLKLIKQMEKDLAFQKQvAEKQLKE---KQKIEL 1317
Cdd:COG3096 471 RRQFEkayelvckiageversqawQTARELLRRYRSQQalaQRLQQLRAQLAELEQRLRQQQN-AERLLEEfcqRIGQQL 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1318 EARRKITEIQYTcRENALPVCPITQATSCRAVTGLQQEHD--KQKAEELKQQVDELTAANRKAEQdMRELTYE------- 1388
Cdd:COG3096 550 DAAEELEELLAE-LEAQLEELEEQAAEAVEQRSELRQQLEqlRARIKELAARAPAWLAAQDALER-LREQSGEaladsqe 627
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1389 -LNALQ--LEKtssEEKARLLKDKLDETNntlRCLKLELERKDQAEKGYSQQLRELGRQLN------------------- 1446
Cdd:COG3096 628 vTAAMQqlLER---EREATVERDELAARK---QALESQIERLSQPGGAEDPRLLALAERLGgvllseiyddvtledapyf 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1447 -------------QTTGKAEEAMQE----ASDLKKIKRNYQLELESLNH----EKGKLQREVDRITR----------AHA 1495
Cdd:COG3096 702 salygparhaivvPDLSAVKEQLAGledcPEDLYLIEGDPDSFDDSVFDaeelEDAVVVKLSDRQWRysrfpevplfGRA 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1496 VAEKNIQHLNS-------QIHSFR-DEKELERL--QICQRKSDHLKEQFEKSHEQLLQNIkaekenNDKIQRLNEELEKS 1565
Cdd:COG3096 782 AREKRLEELRAerdelaeQYAKASfDVQKLQRLhqAFSQFVGGHLAVAFAPDPEAELAAL------RQRRSELERELAQH 855
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1566 NECAEMLKQKVEELTRQNNetklMMQRIQAESEniVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEqdfqRK 1645
Cdd:COG3096 856 RAQEQQLRQQLDQLKEQLQ----LLNKLLPQAN--LLADETLADRLEELREELDAAQEAQAFIQQHGKALAQLE----PL 925
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1646 IKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTK--KEVRNLNAELNASKEEKRRGEQ-------KVQLQQAQVQ--ELNN 1714
Cdd:COG3096 926 VAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFalSEVVQRRPHFSYEDAVGLLGENsdlneklRARLEQAEEArrEARE 1005
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1715 RLKKVQDELhlktieEQMTHRKMVLFQEESGKfKQSAEEFRKKMEKLmeskvitendisGIRLDFVSLQQENSRAQE-NA 1793
Cdd:COG3096 1006 QLRQAQAQY------SQYNQVLASLKSSRDAK-QQTLQELEQELEEL------------GVQADAEAEERARIRRDElHE 1066
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1794 KLCETN--IKELERQLQQYREQMQQGQhmeanhyQKCQKLEDELIAQKREVENLK 1846
Cdd:COG3096 1067 ELSQNRsrRSQLEKQLTRCEAEMDSLQ-------KRLRKAERDYKQEREQVVQAK 1114
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1142-1657 |
2.82e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 2.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1142 ELERMVAELKKQKSRVE--EELPKVREAAENELRKQQRnvedisLQKIRAESEAKQYRRELETIVREKEAAERELERVRQ 1219
Cdd:COG4913 236 DLERAHEALEDAREQIEllEPIRELAERYAAARERLAE------LEYLRAALRLWFAQRRLELLEAELEELRAELARLEA 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1220 LTIEAEAKRAAVEENLLNFRNQLEENTFTRrtledhlkrkdlsLNDLEQQKNKLMEELRRKRDNEEELLKLIKQmekdLA 1299
Cdd:COG4913 310 ELERLEARLDALREELDELEAQIRGNGGDR-------------LEQLEREIERLERELEERERRRARLEALLAA----LG 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1300 FQKQVAEKQLKEKQKIELEARRKITEIQYTCRENAlpvcpiTQATscRAVTGLQQEHDKQKAE--ELKQQV--------- 1368
Cdd:COG4913 373 LPLPASAEEFAALRAEAAALLEALEEELEALEEAL------AEAE--AALRDLRRELRELEAEiaSLERRKsniparlla 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1369 --DELTAANRKAEQDMR---ELtyelnaLQLEKTSSE-----EKA------RLL---------KDKLDETNNTLRcLKLE 1423
Cdd:COG4913 445 lrDALAEALGLDEAELPfvgEL------IEVRPEEERwrgaiERVlggfalTLLvppehyaaaLRWVNRLHLRGR-LVYE 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1424 LERKDQA--------EKGYSQQL------------RELGR-----------QLNQTT--------GKAEEAMQEASDLKK 1464
Cdd:COG4913 518 RVRTGLPdperprldPDSLAGKLdfkphpfrawleAELGRrfdyvcvdspeELRRHPraitragqVKGNGTRHEKDDRRR 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1465 IKRNYQLELEslNHEKGK-LQREVDRITRAHAVAEKNIQHLNSQIHSFRdekelERLQICQRKSDHLKEQFE-KSHEQLL 1542
Cdd:COG4913 598 IRSRYVLGFD--NRAKLAaLEAELAELEEELAEAEERLEALEAELDALQ-----ERREALQRLAEYSWDEIDvASAEREI 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1543 QNIKAEKE----NNDKIQRLNEELEKsnecaemLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALkiqA 1618
Cdd:COG4913 671 AELEAELErldaSSDDLAALEEQLEE-------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA---E 740
|
570 580 590
....*....|....*....|....*....|....*....
gi 4502443 1619 DGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQ 1657
Cdd:COG4913 741 DLARLELRALLEERFAAALGDAVERELRENLEERIDALR 779
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1169-1326 |
3.45e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 47.61 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1169 ENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFT 1248
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQ 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502443 1249 RRtlEDHLKRKdlsLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Cdd:COG1579 96 KE--IESLKRR---ISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
1524-1710 |
3.46e-05 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 49.83 E-value: 3.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1524 QRKSDHLKEQFEKSheQLLQNIKAEKENNDK-IQRLneELEKSNECAEMLK-QKVEELTRQNN-ETKLMMQR--IQAESE 1598
Cdd:NF012221 1541 SQQADAVSKHAKQD--DAAQNALADKERAEAdRQRL--EQEKQQQLAAISGsQSQLESTDQNAlETNGQAQRdaILEESR 1616
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1599 NIVLEKQTIQQRCEALKIQ---------------ADGFKD----QLRSTNEHLHKQ-TKTEQDFQRKIKCLEEDLAKSQN 1658
Cdd:NF012221 1617 AVTKELTTLAQGLDALDSQatyagesgdqwrnpfAGGLLDrvqeQLDDAKKISGKQlADAKQRHVDNQQKVKDAVAKSEA 1696
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1659 LV--SEFKQKCDQQNIIIQNTKKEVRNLNAELN-------------ASKEEKRRGEQKV---QLQQAQVQ 1710
Cdd:NF012221 1697 GVaqGEQNQANAEQDIDDAKADAEKRKDDALAKqneaqqaesdanaAANDAQSRGEQDAsaaENKANQAQ 1766
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1238-1514 |
3.63e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 3.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1238 FRNQ-LEE-NTFTR-RTLEDHLKRkdlsLNDLEQQknklMEELRRKRdneeELLKLIKQMEKDLAfqkqvaekqlkekqk 1314
Cdd:COG4913 213 VREYmLEEpDTFEAaDALVEHFDD----LERAHEA----LEDAREQI----ELLEPIRELAERYA--------------- 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1315 ielEARRKITEIQYtcrenalpvcpitqatscrAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQL 1394
Cdd:COG4913 266 ---AARERLAELEY-------------------LRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALRE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1395 EKTSSEEKARLLK-DKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQT----TGKAEEAMQEASDLKKIKRNY 1469
Cdd:COG4913 324 ELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASaeefAALRAEAAALLEALEEELEAL 403
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 4502443 1470 QLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDE 1514
Cdd:COG4913 404 EEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
1236-1871 |
3.91e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 49.66 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1236 LNFRNQLEENTFTRRTLEDHLKR---KDLSLNDLEQQKNKLMEELRRKRDN---EEELLK----LIKQMEKDLAFQKQVA 1305
Cdd:TIGR01612 561 HEIKKELEEENEDSIHLEKEIKDlfdKYLEIDDEIIYINKLKLELKEKIKNisdKNEYIKkaidLKKIIENNNAYIDELA 640
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1306 E-------KQLKEKQKIELEARRKITEIqYTCRENALpvcpITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAAnrka 1378
Cdd:TIGR01612 641 KispyqvpEHLKNKDKIYSTIKSELSKI-YEDDIDAL----YNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDK---- 711
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1379 EQDMRELTYELNALQLEKTSSEEKARLLKDK---LDETNNTLRCLKLELERKDqaekgysqqlRELGRQLNQTTGKAEEA 1455
Cdd:TIGR01612 712 IQNMETATVELHLSNIENKKNELLDIIVEIKkhiHGEINKDLNKILEDFKNKE----------KELSNKINDYAKEKDEL 781
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1456 MQEASDLKKIKRNY--QLELESLNHEKGKLQREVDR-ITRAHAVAEKNIQHLNSQIHSFRDEKeLERLQICQRKSDHLKE 1532
Cdd:TIGR01612 782 NKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKeYIKTISIKEDEIFKIINEMKFMKDDF-LNKVDKFINFENNCKE 860
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1533 QFEKSHEQ---LLQNIKAEKENndkiQRLNEELEKSNECAEMLkqkveeltrqnNETKlmmQRIQAESENIvlekQTIQQ 1609
Cdd:TIGR01612 861 KIDSEHEQfaeLTNKIKAEISD----DKLNDYEKKFNDSKSLI-----------NEIN---KSIEEEYQNI----NTLKK 918
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1610 RCEALKIqadgFKDQLRSTNEHLHKQTKTEQDFQRKIKCLeedlaKSQNLVSefKQKCDQQNIIIQNTKKEVRNLNAELN 1689
Cdd:TIGR01612 919 VDEYIKI----CENTKESIEKFHNKQNILKEILNKNIDTI-----KESNLIE--KSYKDKFDNTLIDKINELDKAFKDAS 987
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1690 ASKEEKRrgeqkvqlqqaqvqelNNRLKKVQDEL--HLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLmesKVI 1767
Cdd:TIGR01612 988 LNDYEAK----------------NNELIKYFNDLkaNLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNI---EIA 1048
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1768 TENDISGIrldfvsLQQENSRAQENAKLCETNI-KELERQLQQYREQMQQGQHMEANHYQKCQ--KLEDELIAQKREVEN 1844
Cdd:TIGR01612 1049 IHTSIYNI------IDEIEKEIGKNIELLNKEIlEEAEINITNFNEIKEKLKHYNFDDFGKEEniKYADEINKIKDDIKN 1122
|
650 660
....*....|....*....|....*..
gi 4502443 1845 LKQKMDQQIKEHEhqlvllqcEIQKKS 1871
Cdd:TIGR01612 1123 LDQKIDHHIKALE--------EIKKKS 1141
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1143-1326 |
4.02e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.24 E-value: 4.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1143 LERMVAELKKQKSRVEEELPKVR---EAAENELRKQQRNVEDISLqkiraESEAKQYRRELETIvrekeaaERELERVRQ 1219
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRkelEEAEAALEEFRQKNGLVDL-----SEEAKLLLQQLSEL-------ESQLAEARA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1220 LTIEAEAKRAAVEENLLNFRNQLEE--NTFTRRTLEDHLKRKDLSLNDLEQQ---KNKLMEELRRKRDN-EEELLKLIKQ 1293
Cdd:COG3206 234 ELAEAEARLAALRAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAELSARytpNHPDVIALRAQIAAlRAQLQQEAQR 313
|
170 180 190
....*....|....*....|....*....|...
gi 4502443 1294 MEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Cdd:COG3206 314 ILASLEAELEALQAREASLQAQLAQLEARLAEL 346
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1166-1723 |
4.16e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1166 EAAENELRKQQRNVEdiSLQKIRAESEA-KQYRRELETIVREKEA-----AERELERVRQLTIEAEAKRAAVEENLLNFR 1239
Cdd:COG4913 238 ERAHEALEDAREQIE--LLEPIRELAERyAAARERLAELEYLRAAlrlwfAQRRLELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1240 NQLEENTFTRRTLEDHLKRKDLS-LNDLEQQKNKLMEELRRKRDNEEELLKLIKQmekdLAFQKQVAEKQLKEKQKIELE 1318
Cdd:COG4913 316 ARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAA----LGLPLPASAEEFAALRAEAAA 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1319 ARRKITEIQytcrenalpvcpitqatscravtglqqehdkqkaEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTS 1398
Cdd:COG4913 392 LLEALEEEL----------------------------------EALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1399 SEEKARLLKDKL-DETNNTLRCLK-----LELERKDQA------------------EKGYSQQLRE------LGRQLNqt 1448
Cdd:COG4913 438 IPARLLALRDALaEALGLDEAELPfvgelIEVRPEEERwrgaiervlggfaltllvPPEHYAAALRwvnrlhLRGRLV-- 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1449 TGKAEEAMQEAsDLKKIKRN---YQLELES------LNHEKGK------------LQREVDRITRA------HAVAEKNI 1501
Cdd:COG4913 516 YERVRTGLPDP-ERPRLDPDslaGKLDFKPhpfrawLEAELGRrfdyvcvdspeeLRRHPRAITRAgqvkgnGTRHEKDD 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1502 QHLNSQIH--SFRDEKELERLQicqRKSDHLKEQFEKSHEQLlQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEEL 1579
Cdd:COG4913 595 RRRIRSRYvlGFDNRAKLAALE---AELAELEEELAEAEERL-EALEAELDALQERREALQRLAEYSWDEIDVASAEREI 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1580 TRQNNetklmmQRIQAESENIVLEkqtiqqrceALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNL 1659
Cdd:COG4913 671 AELEA------ELERLDASSDDLA---------ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4502443 1660 VSEFKQKCDQQniiiqntkkEVRNLNAELNASKEEKRRGEQKVQLQQaQVQELNNRLKKVQDEL 1723
Cdd:COG4913 736 LEAAEDLARLE---------LRALLEERFAAALGDAVERELRENLEE-RIDALRARLNRAEEEL 789
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
853-1465 |
4.55e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.07 E-value: 4.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 853 KNTQAAEALVKLYETKLCEEEAVIADKNNIENL---ISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDL 929
Cdd:pfam12128 310 LSAADAAVAKDRSELEALEDQHGAFLDADIETAaadQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNN 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 930 -DFDWHKEKADQLVERWQNVHVQIDNRLRDLEgigkslkyyrdtyHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQ 1008
Cdd:pfam12128 390 rDIAGIKDKLAKIREARDRQLAVAEDDLQALE-------------SELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQA 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1009 KMLVSEIEMKQSKMDECQKYAEQYSATVKDYElqtmtyramvDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLM 1088
Cdd:pfam12128 457 TATPELLLQLENFDERIERAREEQEAANAEVE----------RLQSELRQARKRRDQASEALRQASRRLEERQSALDELE 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1089 TQYIKFAGdSLKRLEEEEIKRCKETSEHGAYSDLLQR-------QKATVLENSKLTGKISELERM-VAELKKQKSRVEEE 1160
Cdd:pfam12128 527 LQLFPQAG-TLLHFLRKEAPDWEQSIGKVISPELLHRtdldpevWDGSVGGELNLYGVKLDLKRIdVPEWAASEEELRER 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1161 LPKVREAAENELRKQQRnvedislqkirAESEAKQYRRELETIVREKEAAEREL----ERVRQLTIEAEAKRAAVEENLL 1236
Cdd:pfam12128 606 LDKAEEALQSAREKQAA-----------AEEQLVQANGELEKASREETFARTALknarLDLRRLFDEKQSEKDKKNKALA 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1237 NFRNQLEENtftRRTLEDHLKRKDLSLND-LEQQKnklmeelRRKRDNEEELLKLIKQMEKDLAFQkQVAEKQLKEKQKI 1315
Cdd:pfam12128 675 ERKDSANER---LNSLEAQLKQLDKKHQAwLEEQK-------EQKREARTEKQAYWQVVEGALDAQ-LALLKAAIAARRS 743
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1316 ELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQ-----EHDKQKA--------EELKQQVDELTAANRKAEQDM 1382
Cdd:pfam12128 744 GAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERkieriAVRRQEVlryfdwyqETWLQRRPRLATQLSNIERAI 823
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1383 RELTYELNALQ------LEKTSSEEKArlLKDKLDETNNTLRCLKLELER---------KDQAEKGYSQQLRELGRQLNQ 1447
Cdd:pfam12128 824 SELQQQLARLIadtklrRAKLEMERKA--SEKQQVRLSENLRGLRCEMSKlatlkedanSEQAQGSIGERLAQLEDLKLK 901
|
650
....*....|....*...
gi 4502443 1448 TTGKAEEAMQEASDLKKI 1465
Cdd:pfam12128 902 RDYLSESVKKYVEHFKNV 919
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1121-1455 |
5.00e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 48.74 E-value: 5.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1121 DLLQRQKATV--LENSKLTGKIS--ELERMVAELKKQKSRVEEELPKVREAAENELRKQ---QRNVEDISLQKI---RAE 1190
Cdd:pfam07888 45 ELLQAQEAANrqREKEKERYKRDreQWERQRRELESRVAELKEELRQSREKHEELEEKYkelSASSEELSEEKDallAQR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1191 SEAKQYRRELE----TIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTL-------EDHLKRK 1259
Cdd:pfam07888 125 AAHEARIRELEedikTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLskefqelRNSLAQR 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1260 DLSLNDLEQQKNKLMEEL---RRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALP 1336
Cdd:pfam07888 205 DTQVLQLQDTITTLTQKLttaHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQL 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1337 VCPITQAT----SCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLE----KTSSEEKARLLKD 1408
Cdd:pfam07888 285 TLQLADASlalrEGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVElgreKDCNRVQLSESRR 364
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 4502443 1409 KLDETNNTLRCLKLELERKdQAEKgysQQLRELGRQLNQTTGKAEEA 1455
Cdd:pfam07888 365 ELQELKASLRVAQKEKEQL-QAEK---QELLEYIRQLEQRLETVADA 407
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1077-1449 |
6.44e-05 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 48.92 E-value: 6.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1077 LRTRYTALVTLMT--QYIKFAGDSLKRLEEEEIKRCketsehgaysDLLQRQKATVLENSKLTGK-ISELERMVAELKKQ 1153
Cdd:COG5022 760 LRRRYLQALKRIKkiQVIQHGFRLRRLVDYELKWRL----------FIKLQPLLSLLGSRKEYRSyLACIIKLQKTIKRE 829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1154 KsrveeelpKVREAAENELRkqqRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAA--- 1230
Cdd:COG5022 830 K--------KLRETEEVEFS---LKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSISslk 898
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1231 -----VEENLLNFRNQLEENTFTR--------RTLEDHLKRKDL---SLNDLEQQK--NKLMEELRRKRDNEEELLKLIK 1292
Cdd:COG5022 899 lvnleLESEIIELKKSLSSDLIENlefkteliARLKKLLNNIDLeegPSIEYVKLPelNKLHEVESKLKETSEEYEDLLK 978
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1293 QMEKdLAFQKQVAEKQLKEKQKIELEARRKITEIQY---TCRENALPVCPITQATS--CRAVTGLQQEHDKQKAEELKQQ 1367
Cdd:COG5022 979 KSTI-LVREGNKANSELKNFKKELAELSKQYGALQEstkQLKELPVEVAELQSASKiiSSESTELSILKPLQKLKGLLLL 1057
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1368 VDELTAANRKAEQDMRELT--YELNALQLEKTSSEEKARLLKD-KLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQ 1444
Cdd:COG5022 1058 ENNQLQARYKALKLRRENSllDDKQLYQLESTENLLKTINVKDlEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQ 1137
|
....*
gi 4502443 1445 LNQTT 1449
Cdd:COG5022 1138 LVNTL 1142
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1437-1601 |
7.15e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.84 E-value: 7.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1437 QLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKE 1516
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1517 LERLqicQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECaemLKQKVEELTRQNNETKLMMQRIQAE 1596
Cdd:COG1579 91 YEAL---QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE---LEEKKAELDEELAELEAELEELEAE 164
|
....*
gi 4502443 1597 SENIV 1601
Cdd:COG1579 165 REELA 169
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1082-1308 |
7.31e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 7.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1082 TALVTLMTQYIKFAGDSLKRLEEE--EIKRCKETSEhGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEE 1159
Cdd:COG3883 1 ALALALAAPTPAFADPQIQAKQKElsELQAELEAAQ-AELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1160 ELPKVREAAENELRKQQRNVEDISLQKIRAESE-AKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNF 1238
Cdd:COG3883 80 EIEERREELGERARALYRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1239 RNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQ 1308
Cdd:COG3883 160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1381-1869 |
7.69e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 48.36 E-value: 7.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1381 DMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEAS 1460
Cdd:PRK01156 177 MLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYES 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1461 DLKKIKRNYQLELESLNHEKGkLQREVDRITRAHAVAEKN------------------IQHLNSQIHSFRDE-KELERLQ 1521
Cdd:PRK01156 257 EIKTAESDLSMELEKNNYYKE-LEERHMKIINDPVYKNRNyindyfkykndienkkqiLSNIDAEINKYHAIiKKLSVLQ 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1522 icQRKSDHLKEQFEKshEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETklmMQRIQAESENIV 1601
Cdd:PRK01156 336 --KDYNDYIKKKSRY--DDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEI---LKIQEIDPDAIK 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1602 LEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKC------LEEDlaKSQNLVSEFKQKCDQQNIIIQ 1675
Cdd:PRK01156 409 KELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCpvcgttLGEE--KSNHIINHYNEKKSRLEEKIR 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1676 NTKKEVRNLNAELNASKEEKRRgeqkvqLQQAQVQELNNRLKKVQDELH-LKTIEEQMTHRKmvlfqEESGKFKQSAEEF 1754
Cdd:PRK01156 487 EIEIEVKDIDEKIVDLKKRKEY------LESEEINKSINEYNKIESARAdLEDIKIKINELK-----DKHDKYEEIKNRY 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1755 RKKMEKLMESK---------VITENDISGIRLDFVSLQQE----NSRAQE-------NAKLCETNIKELERQLQQYREQM 1814
Cdd:PRK01156 556 KSLKLEDLDSKrtswlnalaVISLIDIETNRSRSNEIKKQlndlESRLQEieigfpdDKSYIDKSIREIENEANNLNNKY 635
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1815 QQGQHMEANHYQKCQKLED--ELIAQKREVENLKQKMDQQIKEHEHQLVLLQCEIQK 1869
Cdd:PRK01156 636 NEIQENKILIEKLRGKIDNykKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDD 692
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1366-1655 |
8.06e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.21 E-value: 8.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1366 QQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQL 1445
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1446 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNhekgKLQREVDRItrahavaEKNIQhlnSQIHSFRDEKEL-ERLQICQ 1524
Cdd:COG1340 81 DELNEKLNELREELDELRKELAELNKAGGSID----KLRKEIERL-------EWRQQ---TEVLSPEEEKELvEKIKELE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1525 RKSDHLKEQFEKSHE--QLLQNIKAEKENNDKI-QRLNEELEKSNEC-AEM--LKQKVEELTRQNNETKLMMQRIQAESE 1598
Cdd:COG1340 147 KELEKAKKALEKNEKlkELRAELKELRKEAEEIhKKIKELAEEAQELhEEMieLYKEADELRKEADELHKEIVEAQEKAD 226
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1599 NIVLEKQTIQQRCEALKIQADGFKDQLRSTnehlhKQTKTEQDFQRKIKCLEEDLAK 1655
Cdd:COG1340 227 ELHEEIIELQKELRELRKELKKLRKKQRAL-----KREKEKEELEEKAEEIFEKLKK 278
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1621-1818 |
9.39e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 9.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1621 FKDQLRSTNEHLHKQT-KTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQqniiIQNTKKEVRNLNAELNASKEEKRRGE 1699
Cdd:COG4717 47 LLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEE----LEELEEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1700 QKVQLQQ--AQVQELNNRLKKVQDELhlKTIEEQMTHRKMVLFQEESgkFKQSAEEFRKKMEKLMESK-VITENDISGIR 1776
Cdd:COG4717 123 KLLQLLPlyQELEALEAELAELPERL--EELEERLEELRELEEELEE--LEAELAELQEELEELLEQLsLATEEELQDLA 198
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 4502443 1777 LDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQ 1818
Cdd:COG4717 199 EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1148-1381 |
9.56e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 9.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1148 AELKKQKSRVEEELpkvrEAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERvRQLTIEAEAK 1227
Cdd:COG3883 19 QAKQKELSELQAEL----EAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE-RREELGERAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1228 RAAVEENLLNFRNQLeentFTRRTLEDHLKRKDLsLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEK 1307
Cdd:COG3883 94 ALYRSGGSVSYLDVL----LGSESFSDFLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEA 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4502443 1308 QLKEKQKIELEARRKITEIQytcrenalpvcpITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQD 1381
Cdd:COG3883 169 AKAELEAQQAEQEALLAQLS------------AEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
375-469 |
9.88e-05 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 43.85 E-value: 9.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 375 LHNFVSRATNELIWLNEKEE----EEVAYDWSErntnIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTI 450
Cdd:pfam00435 3 LQQFFRDADDLESWIEEKEAllssEDYGKDLES----VQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEEI 78
|
90
....*....|....*....
gi 4502443 451 EAYRAAMQTQWSWILQLCQ 469
Cdd:pfam00435 79 QERLEELNERWEQLLELAA 97
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1167-1564 |
1.30e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1167 AAENELRKQQRNVEDI--SLQKIRAESEAKQYR-----RELETIVREKEAAERELERVR---QLTIEAEA-----KRAAV 1231
Cdd:PRK04863 276 RHANERRVHLEEALELrrELYTSRRQLAAEQYRlvemaRELAELNEAESDLEQDYQAASdhlNLVQTALRqqekiERYQA 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1232 EENLLNFRnqLEENTFTRrtledhlkrkdlslndlEQQKNKLMEELRRKRDNEEELLKLikqmekdlafQKQVAEKQlke 1311
Cdd:PRK04863 356 DLEELEER--LEEQNEVV-----------------EEADEQQEENEARAEAAEEEVDEL----------KSQLADYQ--- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1312 kQKIELEARRKIteiQYTCRENALpvcpiTQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMR-------- 1383
Cdd:PRK04863 404 -QALDVQQTRAI---QYQQAVQAL-----ERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSvaqaahsq 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1384 -ELTYEL---------------NALQLEKTSSEEKArllkdkLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQ 1447
Cdd:PRK04863 475 fEQAYQLvrkiagevsrseawdVARELLRRLREQRH------LAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGK 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1448 TTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRahavaekNIQHLNSQIHSFRDEKE-LERLQicqrk 1526
Cdd:PRK04863 549 NLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQA-------RIQRLAARAPAWLAAQDaLARLR----- 616
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 4502443 1527 sDHLKEQFEKSHE------QLLQNIKAEKENNDKI----QRLNEELEK 1564
Cdd:PRK04863 617 -EQSGEEFEDSQDvteymqQLLERERELTVERDELaarkQALDEEIER 663
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
1152-1591 |
1.34e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 47.16 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1152 KQKSRVEEELPKVREAAEN-ELRKQQRNVEDISLQKIRAESEAKQYRRELETIV----REKEAAERELERVRQLTIEAEA 1226
Cdd:pfam06160 60 KSLPDIEELLFEAEELNDKyRFKKAKKALDEIEELLDDIEEDIKQILEELDELLeseeKNREEVEELKDKYRELRKTLLA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1227 KRAAVEENLLNFRNQLEE-----NTFTRRTLE-DHLKRKDLsLNDLEQQKNKLMEELrrkrdneEELLKLIKQMEKDlaF 1300
Cdd:pfam06160 140 NRFSYGPAIDELEKQLAEieeefSQFEELTESgDYLEAREV-LEKLEEETDALEELM-------EDIPPLYEELKTE--L 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1301 QKQVAE-----KQLKEKQKI--ELEARRKITEIqytcrenalpvcpitqatscravtglqqehdKQKAEELKQQVDELTA 1373
Cdd:pfam06160 210 PDQLEElkegyREMEEEGYAleHLNVDKEIQQL-------------------------------EEQLEENLALLENLEL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1374 ANrkAEQDMRELTYELNAL--QLEKtssEEKARL--------LKDKLDETNNTLRCLKLELERKDQA----------EKG 1433
Cdd:pfam06160 259 DE--AEEALEEIEERIDQLydLLEK---EVDAKKyveknlpeIEDYLEHAEEQNKELKEELERVQQSytlnenelerVRG 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1434 YSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRd 1513
Cdd:pfam06160 334 LEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIK- 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1514 eKELERLQIcQRKSDHLKEQFEKSHEQL--LQNIKAEKENNdkIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQ 1591
Cdd:pfam06160 413 -RLVEKSNL-PGLPESYLDYFFDVSDEIedLADELNEVPLN--MDEVNRLLDEAQDDVDTLYEKTEELIDNATLAEQLIQ 488
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1670-1870 |
1.35e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1670 QNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELhlKTIEEQMThrkmvLFQEESGKFKQ 1749
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI--RALEQELA-----ALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1750 SAEEFRKKMEKLME--SKVITENDISGI--RLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEA--- 1822
Cdd:COG4942 91 EIAELRAELEAQKEelAELLRALYRLGRqpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAele 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 4502443 1823 NHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQCEIQKK 1870
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1626-1873 |
1.37e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.43 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1626 RSTNEHlHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQ--KCDQQNIIIQNT-KKEVRNLNAELNASKEEKRRGEQKV 1702
Cdd:pfam17380 282 KAVSER-QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEaeKARQAEMDRQAAiYAEQERMAMERERELERIRQEERKR 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1703 QLQQAQVQELNNRLKKVQdELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMeskvitendisgIRLDFVSL 1782
Cdd:pfam17380 361 ELERIRQEEIAMEISRMR-ELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQK------------VEMEQIRA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1783 QQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHM---EANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQ 1859
Cdd:pfam17380 428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507
|
250 260
....*....|....*....|.
gi 4502443 1860 LV-------LLQCEIQKKSTA 1873
Cdd:pfam17380 508 MIeeerkrkLLEKEMEERQKA 528
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1654-1864 |
1.45e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1654 AKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKtiEEQMT 1733
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEER--REELG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1734 HRkMVLFQEESGKFK--------QSAEEFRKKMEKLmesKVITENDISGIRlDFVSLQQENSRAQENAKLCETNIKELER 1805
Cdd:COG3883 90 ER-ARALYRSGGSVSyldvllgsESFSDFLDRLSAL---SKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 4502443 1806 QLQQYREQMQQGQhmeanhyQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQ 1864
Cdd:COG3883 165 ELEAAKAELEAQQ-------AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2515-2552 |
1.51e-04 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 40.93 E-value: 1.51e-04
10 20 30
....*....|....*....|....*....|....*...
gi 4502443 2515 QQLRQCELVITGIGHPITNKMMSVVEAVNANIINKEMG 2552
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2242-2274 |
1.51e-04 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 40.93 E-value: 1.51e-04
10 20 30
....*....|....*....|....*....|...
gi 4502443 2242 KHILEAQIASGGVIDPVRGIRVPPEIALQQGLL 2274
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLI 33
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
1172-1326 |
1.53e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 47.01 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1172 LRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAavEENLLNFRNQLEENTFTRRT 1251
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQRE--EERLVQKEEQLDARAEKLDN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1252 LEDHLKRKDLSLND----LEQQKNKLMEELRRKRDNEEELLK--LIKQMEKDLAFQKQVAEKQLKEkqKIELEARRKITE 1325
Cdd:PRK12705 103 LENQLEEREKALSAreleLEELEKQLDNELYRVAGLTPEQARklLLKLLDAELEEEKAQRVKKIEE--EADLEAERKAQN 180
|
.
gi 4502443 1326 I 1326
Cdd:PRK12705 181 I 181
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1139-1298 |
1.83e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1139 KISELERMVAELKKQKSRVEEELpkvrEAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETI---------VREKEA 1209
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDEL----AALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeeqlgnvrnNKEYEA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1210 AERELErvrqltiEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDlslNDLEQQKNKLMEELRRKRDNEEELLK 1289
Cdd:COG1579 94 LQKEIE-------SLKRRISDLEDEILELMERIEELEEELAELEAELAELE---AELEEKKAELDEELAELEAELEELEA 163
|
....*....
gi 4502443 1290 LIKQMEKDL 1298
Cdd:COG1579 164 EREELAAKI 172
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1141-1757 |
1.83e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.14 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1141 SELERMVAELKKQKSRVEEELP--KVREA---AENELRKQQRNvEDISLQKIRAESEAKqyRRELETIVREKEAA----E 1211
Cdd:pfam12128 426 EQLEAGKLEFNEEEYRLKSRLGelKLRLNqatATPELLLQLEN-FDERIERAREEQEAA--NAEVERLQSELRQArkrrD 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1212 RELERVRQLTIEAEAKRAAVEE----------NLLNFRN---QLEENTFTRRTLEDHLKRKDL-----------SLN--- 1264
Cdd:pfam12128 503 QASEALRQASRRLEERQSALDElelqlfpqagTLLHFLRkeaPDWEQSIGKVISPELLHRTDLdpevwdgsvggELNlyg 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1265 ---DLEQ----QKNKLMEELRRKRDNEEELLK----LIKQMEKDLAfqkqVAEKQLKEKQKIELEARRKITEiqytCREN 1333
Cdd:pfam12128 583 vklDLKRidvpEWAASEEELRERLDKAEEALQsareKQAAAEEQLV----QANGELEKASREETFARTALKN----ARLD 654
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1334 alpvcpitqatscravtgLQQEHDKQKAEELKQQvDELTAANRKAEQDMRELTYELNALQLEktsseekarlLKDKLDET 1413
Cdd:pfam12128 655 ------------------LRRLFDEKQSEKDKKN-KALAERKDSANERLNSLEAQLKQLDKK----------HQAWLEEQ 705
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1414 NNTLRCLKLELERKDQAEKGysqqlrELGRQLNQ-TTGKAEEAMQEASDLKKIKRNYQLELESLNhekgklqrevdritr 1492
Cdd:pfam12128 706 KEQKREARTEKQAYWQVVEG------ALDAQLALlKAAIAARRSGAKAELKALETWYKRDLASLG--------------- 764
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1493 ahaVAEKNIQHLNSQIHSFrdEKELERlqICQRKSDHLKEQFEKSHEQLLQNikaekenndkiQRLNEELEKSNECAEML 1572
Cdd:pfam12128 765 ---VDPDVIAKLKREIRTL--ERKIER--IAVRRQEVLRYFDWYQETWLQRR-----------PRLATQLSNIERAISEL 826
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1573 KQkveELTRQNNETKLmmQRIQAESENIVLEKQTIQqrceaLKIQADGFKDQLRSTNE-HLHKQT-KTEQDFQRKIKCLE 1650
Cdd:pfam12128 827 QQ---QLARLIADTKL--RRAKLEMERKASEKQQVR-----LSENLRGLRCEMSKLATlKEDANSeQAQGSIGERLAQLE 896
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1651 EDLAKSQNLVSEFKQKCDQQNIIIqntKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELnnrLKKVQDELHLKTIEE 1730
Cdd:pfam12128 897 DLKLKRDYLSESVKKYVEHFKNVI---ADHSGSGLAETWESLREEDHYQNDKGIRLLDYRKL---VPYLEQWFDVRVPQS 970
|
650 660
....*....|....*....|....*...
gi 4502443 1731 QMTHRKMV-LFQEESGKFKQSAEEFRKK 1757
Cdd:pfam12128 971 IMVLREQVsILGVDLTEFYDVLADFDRR 998
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1358-1596 |
1.86e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 47.21 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1358 KQKAEELKQQVDEltaanrkAEQDMRELTYELNALQlEKTSSEEKARL-------LKDKLDETNNTLRCLKLEL------ 1424
Cdd:PRK11281 79 KEETEQLKQQLAQ-------APAKLRQAQAELEALK-DDNDEETRETLstlslrqLESRLAQTLDQLQNAQNDLaeynsq 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1425 --------ERKDQAEKGYSQQLRELGRQLNqtTGKAEEAMQEASDLKKikrnYQLELESLNhEKGKLQREV--------D 1488
Cdd:PRK11281 151 lvslqtqpERAQAALYANSQRLQQIRNLLK--GGKVGGKALRPSQRVL----LQAEQALLN-AQNDLQRKSlegntqlqD 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1489 RITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKI-QRLNEELEKSNe 1567
Cdd:PRK11281 224 LLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLsQRLLKATEKLN- 302
|
250 260 270
....*....|....*....|....*....|
gi 4502443 1568 caemlkqkveELTRQNNETKLMMQR-IQAE 1596
Cdd:PRK11281 303 ----------TLTQQNLRVKNWLDRlTQSE 322
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1378-1640 |
1.97e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.43 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1378 AEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQ 1457
Cdd:COG4372 29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1458 EASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKS 1537
Cdd:COG4372 109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1538 HEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQ 1617
Cdd:COG4372 189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268
|
250 260
....*....|....*....|...
gi 4502443 1618 ADGFKDQLRSTNEHLHKQTKTEQ 1640
Cdd:COG4372 269 VEKDTEEEELEIAALELEALEEA 291
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1124-1579 |
2.41e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.71 E-value: 2.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1124 QRQKATVLENskltgKISELERMVAELKKQKSRVEEElpkvREAAENELRKQQ-------RNVEDISLQKIRAESEAKQY 1196
Cdd:pfam01576 592 QRQLVSNLEK-----KQKKFDQMLAEEKAISARYAEE----RDRAEAEAREKEtralslaRALEEALEAKEELERTNKQL 662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1197 RRELETIVREKEAAER---ELERvrqltieaeAKRAAvEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQ---- 1269
Cdd:pfam01576 663 RAEMEDLVSSKDDVGKnvhELER---------SKRAL-EQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQferd 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1270 ---KNKLMEELRRK-----RDNEEELLKLIKQMEKDLAFQKQV------AEKQLKEKQKIELEARRKITEIQYTCRENAL 1335
Cdd:pfam01576 733 lqaRDEQGEEKRRQlvkqvRELEAELEDERKQRAQAVAAKKKLeldlkeLEAQIDAANKGREEAVKQLKKLQAQMKDLQR 812
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1336 PvCPITQATSCRAVTGLQQEHDKQKA--EELKQQVDELTAANR---KAEQDMRELTYEL-------NALQLEKTSSEEKA 1403
Cdd:pfam01576 813 E-LEEARASRDEILAQSKESEKKLKNleAELLQLQEDLAASERarrQAQQERDELADEIasgasgkSALQDEKRRLEARI 891
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1404 RLLKDKLDETNNTLRCLKLELERKDQ----------AEKGYSQQLRELGRQLNQTTGKAEEAMQEASdlKKIKRNYQLEL 1473
Cdd:pfam01576 892 AQLEEELEEEQSNTELLNDRLRKSTLqveqlttelaAERSTSQKSESARQQLERQNKELKAKLQEME--GTVKSKFKSSI 969
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1474 ESLNHEKGKLQREVDRITRAHAVAEKNIQhlnsqihsfRDEKELERLQIC----QRKSDHLKEQFEKSHEQLLQNIKAEK 1549
Cdd:pfam01576 970 AALEAKIAQLEEQLEQESRERQAANKLVR---------RTEKKLKEVLLQvedeRRHADQYKDQAEKGNSRMKQLKRQLE 1040
|
490 500 510
....*....|....*....|....*....|....*..
gi 4502443 1550 ENNDKIQRLN-------EELEKSNECAEMLKQKVEEL 1579
Cdd:pfam01576 1041 EAEEEASRANaarrklqRELDDATESNESMNREVSTL 1077
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1197-1605 |
2.59e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1197 RRELETIVREKEAAERELERVRQltieaEAKRAaveenllnfRNQLEEntfTRRTLEDHLKRkdlslndleqqknkLMEE 1276
Cdd:pfam07888 40 LQERAELLQAQEAANRQREKEKE-----RYKRD---------REQWER---QRRELESRVAE--------------LKEE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1277 LRRKRDNEEEllklikqmekdlafqkqvaekqLKEKQKIELEARRKITEIqytcrenalpvcpitqatscRAVTGLQQEH 1356
Cdd:pfam07888 89 LRQSREKHEE----------------------LEEKYKELSASSEELSEE--------------------KDALLAQRAA 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1357 DKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELE--RKDQAEKGY 1434
Cdd:pfam07888 127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQelRNSLAQRDT 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 S-QQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVdritrAHAVAEKNiqHLNSQIHSFRD 1513
Cdd:pfam07888 207 QvLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEEL-----SSMAAQRD--RTQAELHQARL 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1514 EKELERLQICQrKSDHLKE---QFEKSHEQLLQNIKAEKennDKIQRLNEELEKSNEC---AEMLKQKVE---------- 1577
Cdd:pfam07888 280 QAAQLTLQLAD-ASLALREgraRWAQERETLQQSAEADK---DRIEKLSAELQRLEERlqeERMEREKLEvelgrekdcn 355
|
410 420 430
....*....|....*....|....*....|...
gi 4502443 1578 -----ELTRQNNETKLMMQRIQAESENIVLEKQ 1605
Cdd:pfam07888 356 rvqlsESRRELQELKASLRVAQKEKEQLQAEKQ 388
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1420-1581 |
4.12e-04 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 45.34 E-value: 4.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1420 LKLELERKDQAekgysqqLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEK 1499
Cdd:PRK09039 44 LSREISGKDSA-------LDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1500 NIQHLNSQIHSFRDEKELERLQIcqrksDHLKEQFEKSHEQL--LQNI-----KAEKENNDKIQRLNEELEKSnecaemL 1572
Cdd:PRK09039 117 RAGELAQELDSEKQVSARALAQV-----ELLNQQIAALRRQLaaLEAAldaseKRDRESQAKIADLGRRLNVA------L 185
|
....*....
gi 4502443 1573 KQKVEELTR 1581
Cdd:PRK09039 186 AQRVQELNR 194
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
1142-1327 |
4.20e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 45.71 E-value: 4.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1142 ELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEakQYRREletivrekeaaerELERVRQLT 1221
Cdd:pfam15709 349 EVERKRREQEEQRRLQQEQLERAEKMREELELEQQRRFEEIRLRKQRLEEE--RQRQE-------------EEERKQRLQ 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1222 IEAEAKRAaveenllnfRNQLEEntFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQ 1301
Cdd:pfam15709 414 LQAAQERA---------RQQQEE--FRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQRQ 482
|
170 180
....*....|....*....|....*.
gi 4502443 1302 KQVAEkqlkEKQKIELEARRKITEIQ 1327
Cdd:pfam15709 483 KQEAE----EKARLEAEERRQKEEEA 504
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
745-943 |
4.42e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.87 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 745 EVRNIRLRLENC---EDRLIRQIRTPLERddlhESVFRiTEQEKLKKELERLKDDLGTITNKCEE-FFSQAAASSSVPTL 820
Cdd:pfam05483 514 ELKKHQEDIINCkkqEERMLKQIENLEEK----EMNLR-DELESVREEFIQKGDEVKCKLDKSEEnARSIEYEVLKKEKQ 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 821 RSELNVVLQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEA-LVKLYETKLCEEEAVIAD-KNNIENLISTlkqWRSEVDE 898
Cdd:pfam05483 589 MKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENkQLNAYEIKVNKLELELASaKQKFEEIIDN---YQKEIED 665
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 4502443 899 KRQVFHALEDELQKAKAISDEMFKTYKERDLD-----------FDWHKEKADQLVE 943
Cdd:pfam05483 666 KKISEEKLLEEVEKAKAIADEAVKLQKEIDKRcqhkiaemvalMEKHKHQYDKIIE 721
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1359-1863 |
4.62e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.98 E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1359 QKAEELKQQVDELTAANRKAEQDMRELTYELNALQlektssEEKARLLKDKLDEtnntlrcLKLELERKDQaekgYSQQL 1438
Cdd:pfam12128 294 TLDDQWKEKRDELNGELSAADAAVAKDRSELEALE------DQHGAFLDADIET-------AAADQEQLPS----WQSEL 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1439 RELGRQLNQTTGKAEEaMQEASDLKKIKRNYQLELE-SLNHEKGKLQREVdrITRAHAVAEKNIQHL--------NSQIH 1509
Cdd:pfam12128 357 ENLEERLKALTGKHQD-VTAKYNRRRSKIKEQNNRDiAGIKDKLAKIREA--RDRQLAVAEDDLQALeselreqlEAGKL 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1510 SFRDEK----------------------ELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNE 1567
Cdd:pfam12128 434 EFNEEEyrlksrlgelklrlnqatatpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASR 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1568 CAEMLKQKVEELTRQ------------NNETKLMMQRI---------------------QAESEN----IVLEKQTIQ-- 1608
Cdd:pfam12128 514 RLEERQSALDELELQlfpqagtllhflRKEAPDWEQSIgkvispellhrtdldpevwdgSVGGELnlygVKLDLKRIDvp 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1609 ---QRCEALKIQADGFK--------------DQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQ- 1670
Cdd:pfam12128 594 ewaASEEELRERLDKAEealqsarekqaaaeEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAl 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1671 NIIIQNTKKEVRNLNAELNASKEekrrgEQKVQLQQAQVQELNNRLKKVQDELHL-KTIEEQMTHRKMVLFQEESGKfKQ 1749
Cdd:pfam12128 674 AERKDSANERLNSLEAQLKQLDK-----KHQAWLEEQKEQKREARTEKQAYWQVVeGALDAQLALLKAAIAARRSGA-KA 747
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1750 SAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENaklcETNIKELERQLQ-QYREQMQQGQHMEANHYQKC 1828
Cdd:pfam12128 748 ELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR----RQEVLRYFDWYQeTWLQRRPRLATQLSNIERAI 823
|
570 580 590
....*....|....*....|....*....|....*
gi 4502443 1829 QKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLL 1863
Cdd:pfam12128 824 SELQQQLARLIADTKLRRAKLEMERKASEKQQVRL 858
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1154-1334 |
4.70e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 4.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1154 KSRVEEELPKVREAAENELRKQQRNVEDISLQKIR-AESEAKQYRRELETIVREKEaaeRELERVrqltieaeakraavE 1232
Cdd:PRK12704 26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLeAKEEIHKLRNEFEKELRERR---NELQKL--------------E 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1233 ENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAfqKQVAEKQLKEk 1312
Cdd:PRK12704 89 KRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEA--KEILLEKVEE- 165
|
170 180
....*....|....*....|..
gi 4502443 1313 qKIELEARRKITEIQYTCRENA 1334
Cdd:PRK12704 166 -EARHEAAVLIKEIEEEAKEEA 186
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1135-1220 |
6.53e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 45.23 E-value: 6.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1135 KLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQqrnvedislQKIRA-ESEAKQYRRELETIVREKEAAERE 1213
Cdd:COG2433 424 RLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKD---------REISRlDREIERLERELEEERERIEELKRK 494
|
....*..
gi 4502443 1214 LERVRQL 1220
Cdd:COG2433 495 LERLKEL 501
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1531-1875 |
7.44e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.11 E-value: 7.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1531 KEQFEKSHEQLLQNIKaekennDKIQRLNEELEKSNECAEMLKQKVEELtrqnnETKLmmQRIQAESENIVLEKQTIQQR 1610
Cdd:pfam15921 73 KEHIERVLEEYSHQVK------DLQRRLNESNELHEKQKFYLRQSVIDL-----QTKL--QEMQMERDAMADIRRRESQS 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1611 CEALKiqadgfkDQLRSTNEHLHKQtkteqdfqrkiKCLEEDLAKSQNL-VSEFKQKCDQQNIIIQntkkEVRNLNAELN 1689
Cdd:pfam15921 140 QEDLR-------NQLQNTVHELEAA-----------KCLKEDMLEDSNTqIEQLRKMMLSHEGVLQ----EIRSILVDFE 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1690 ASKEEKRRgeQKVQLQQAQVQELNNRLKKVqdelhLKTIEEQMTHRKMVLFQEESgKFKQSAEEFRKKMEKLMES-KVIT 1768
Cdd:pfam15921 198 EASGKKIY--EHDSMSTMHFRSLGSAISKI-----LRELDTEISYLKGRIFPVED-QLEALKSESQNKIELLLQQhQDRI 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1769 ENDISGIRLDFVSLQQENSRAQENAKlcetnikELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVenlKQK 1848
Cdd:pfam15921 270 EQLISEHEVEITGLTEKASSARSQAN-------SIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA---KRM 339
|
330 340
....*....|....*....|....*..
gi 4502443 1849 MDQQIKEHEHQLVLLQCEIQKKSTAKD 1875
Cdd:pfam15921 340 YEDKIEELEKQLVLANSELTEARTERD 366
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1067-1295 |
7.50e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 7.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1067 ADLIIQEFMD--LRTRYTALvtlmTQYIKFAGDSLKRLEEEeikrcKETSEHgAYSDLLQRQKATVL--ENSKLTGKISE 1142
Cdd:COG3206 154 ANALAEAYLEqnLELRREEA----RKALEFLEEQLPELRKE-----LEEAEA-ALEEFRQKNGLVDLseEAKLLLQQLSE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1143 LERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAE-SEAKQYRRELETIVREK----EAAERELERV 1217
Cdd:COG3206 224 LESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQlAELEAELAELSARYTPNhpdvIALRAQIAAL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1218 RQLtIEAEAKRAaveenLLNFRNQLEENTFTRRTLE---DHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQM 1294
Cdd:COG3206 304 RAQ-LQQEAQRI-----LASLEAELEALQAREASLQaqlAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEA 377
|
.
gi 4502443 1295 E 1295
Cdd:COG3206 378 R 378
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1371-1582 |
8.23e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 8.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1371 LTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTG 1450
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1451 KAEEAMQEasdLKKIKRNYQLELESL----NHEKGKL---QREVDRITRAHAVAEKNIQHLNSQIHSFRDE-KELERLQI 1522
Cdd:COG4942 91 EIAELRAE---LEAQKEELAELLRALyrlgRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADlAELAALRA 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4502443 1523 CQRKSDHLKEQFEKSHEQLLQNIKAEK-ENNDKIQRLNEELEKSNECAEMLKQKVEELTRQ 1582
Cdd:COG4942 168 ELEAERAELEALLAELEEERAALEALKaERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1353-1852 |
1.02e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.43 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1353 QQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKL---DETNNTLR----CLKLELE 1425
Cdd:pfam10174 276 QMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLtakEQRAAILQtevdALRLRLE 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1426 RKDQAEKGYSQQLRELGRQLNQTTGKAEEaMQEASDLKKIKRNyqleleslnhekgklqrevdritrahaVAEKNIQHLN 1505
Cdd:pfam10174 356 EKESFLNKKTKQLQDLTEEKSTLAGEIRD-LKDMLDVKERKIN---------------------------VLQKKIENLQ 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1506 SQIhsfRD-EKEL----ERLQICQRKSDHLK------EQFEKSHEQLLQNIKAEKENNDKIQRlnEELEKSNECAEMLKQ 1574
Cdd:pfam10174 408 EQL---RDkDKQLaglkERVKSLQTDSSNTDtalttlEEALSEKERIIERLKEQREREDRERL--EELESLKKENKDLKE 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1575 KVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHK------QTKTEQDFQRKIKC 1648
Cdd:pfam10174 483 KVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKahnaeeAVRTNPEINDRIRL 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1649 LEEDlaksqnlVSEFKQKCDQqniiiqnTKKEVRNLNAELNASKEEKRRGEQKVqlqqAQVQELNNRLKKVQD--ELHLK 1726
Cdd:pfam10174 563 LEQE-------VARYKEESGK-------AQAEVERLLGILREVENEKNDKDKKI----AELESLTLRQMKEQNkkVANIK 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1727 TIEEQMTHRKMVLFQEESGKFKQSAEEFR-KKMEKLME--SKVITENDISGIRLDfvSLQQenSRAQENAKLceTNIK-E 1802
Cdd:pfam10174 625 HGQQEMKKKGAQLLEEARRREDNLADNSQqLQLEELMGalEKTRQELDATKARLS--STQQ--SLAEKDGHL--TNLRaE 698
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4502443 1803 LERQLQQYREQMQQG-----QHMEAN------HYQKCQKLEDELIAQKREVENLKQKMDQQ 1852
Cdd:pfam10174 699 RRKQLEEILEMKQEAllaaiSEKDANiallelSSSKKKKTQEEVMALKREKDRLVHQLKQQ 759
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
1142-1322 |
1.07e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.07 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1142 ELERMVAELKKQKSRVEEELPKVREAAENelRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERElervrqlt 1221
Cdd:TIGR02794 51 QANRIQQQKKPAAKKEQERQKKLEQQAEE--AEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQ-------- 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1222 iEAEAKRAAVEEnllnfRNQLEENTFTRRTLEDHLKRKDlslndlEQQKNKLMEELRRKRDnEEELLKLIKQMEKDLAFQ 1301
Cdd:TIGR02794 121 -AEEAKAKQAAE-----AKAKAEAEAERKAKEEAAKQAE------EEAKAKAAAEAKKKAE-EAKKKAEAEAKAKAEAEA 187
|
170 180
....*....|....*....|....*
gi 4502443 1302 KQVAE----KQLKEKQKIELEARRK 1322
Cdd:TIGR02794 188 KAKAEeakaKAEAAKAKAAAEAAAK 212
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1278-1564 |
1.12e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1278 RRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIeLEARRKITEIQYTcrenalpvcPITQATSCRAVTGLQQEHD 1357
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQER-REALQRLAEYSWD---------EIDVASAEREIAELEAELE 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1358 KQKA-----EELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDEtnntlrclklelerkdqAEK 1432
Cdd:COG4913 679 RLDAssddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA-----------------AED 741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1433 GYSQQLRELGRQlnqttgKAEEAMQEASdLKKIKRNYQLELESLNHEKGKLQREVDRITRAH-AVAEKNIQHLNSQIHSF 1511
Cdd:COG4913 742 LARLELRALLEE------RFAAALGDAV-ERELRENLEERIDALRARLNRAEEELERAMRAFnREWPAETADLDADLESL 814
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4502443 1512 RD-EKELERLqicqrKSDHLKEQFEKSHEQLLQNIKAEKEN------------NDKIQRLNEELEK 1564
Cdd:COG4913 815 PEyLALLDRL-----EEDGLPEYEERFKELLNENSIEFVADllsklrraireiKERIDPLNDSLKR 875
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1064-1234 |
1.18e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1064 QSSADLIIQEFMDLRTRYTALvTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLE----NSKLTGK 1139
Cdd:COG3206 211 SEEAKLLLQQLSELESQLAEA-RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAElaelSARYTPN 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1140 ISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQY---RRELETIVREKEAAERELER 1216
Cdd:COG3206 290 HPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYES 369
|
170
....*....|....*...
gi 4502443 1217 VRQLTIEAEAKRAAVEEN 1234
Cdd:COG3206 370 LLQRLEEARLAEALTVGN 387
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
1536-1722 |
1.39e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 42.59 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1536 KSHEQLLQNIKA-----EKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQriQAESENIVLEKQTIQQr 1610
Cdd:pfam13851 4 KNHEKAFNEIKNyyndiTRNNLELIKSLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQ--KAQEEVEELRKQLENY- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1611 cEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEED----LAKSQNLVSEFKQKCDQQNIIIQntkKEVRNLNA 1686
Cdd:pfam13851 81 -EKDKQSLKNLKARLKVLEKELKDLKWEHEVLEQRFEKVERErdelYDKFEAAIQDVQQKTGLKNLLLE---KKLQALGE 156
|
170 180 190
....*....|....*....|....*....|....*...
gi 4502443 1687 ELNasKEEKRRGE--QKVQLQQAQVQELNNRLKKVQDE 1722
Cdd:pfam13851 157 TLE--KKEAQLNEvlAAANLDPDALQAVTEKLEDVLES 192
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1156-1496 |
1.49e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1156 RVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENL 1235
Cdd:COG4372 3 RLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEEL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1236 LNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKI 1315
Cdd:COG4372 83 EELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1316 ELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLE 1395
Cdd:COG4372 163 QEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDAL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1396 KTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELES 1475
Cdd:COG4372 243 ELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALL 322
|
330 340
....*....|....*....|.
gi 4502443 1476 LNHEKGKLQREVDRITRAHAV 1496
Cdd:COG4372 323 ELAKKLELALAILLAELADLL 343
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
1141-1466 |
1.52e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 43.37 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1141 SELERMVAELKKQKSRVEEELPKVREAAENELRKQqrnVEDISLQKIRAESEAKQYRRELETiVREKEAAERelervrql 1220
Cdd:pfam00038 28 KLLETKISELRQKKGAEPSRLYSLYEKEIEDLRRQ---LDTLTVERARLQLELDNLRLAAED-FRQKYEDEL-------- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1221 tieaeAKRAAVEENLLNFRNQLEENTFTRrtledhlkrkdlslNDLEQQKNKLMEELR-RKRDNEEEllklIKQMEKDLA 1299
Cdd:pfam00038 96 -----NLRTSAENDLVGLRKDLDEATLAR--------------VDLEAKIESLKEELAfLKKNHEEE----VRELQAQVS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1300 FQKQVAEkqLKEKQKIEL-----EARRKITEIQYTCRENAlpvcpitqatscravtglqQEHDKQKAEELKQQVDELTAA 1374
Cdd:pfam00038 153 DTQVNVE--MDAARKLDLtsalaEIRAQYEEIAAKNREEA-------------------EEWYQSKLEELQQAAARNGDA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1375 NRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNntlrclklelERKDQAEKGYSQQLRELGRQLNQTTGKAEE 1454
Cdd:pfam00038 212 LRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETE----------ERYELQLADYQELISELEAELQETRQEMAR 281
|
330
....*....|..
gi 4502443 1455 AMQEASDLKKIK 1466
Cdd:pfam00038 282 QLREYQELLNVK 293
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1550-1872 |
1.52e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.94 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1550 ENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNnETKLMMQRIQAESENIVLEKQTIQQRCEALKIQAD--GFKDQLRS 1627
Cdd:pfam05483 71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEiqENKDLIKE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1628 TNEHLHKQTKTEQDFQR---KIKCLEEDLAKSQNLVSEFKQKCDQqnIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQL 1704
Cdd:pfam05483 150 NNATRHLCNLLKETCARsaeKTKKYEYEREETRQVYMDLNNNIEK--MILAFEELRVQAENARLEMHFKLKEDHEKIQHL 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1705 QQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQ 1784
Cdd:pfam05483 228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQR 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1785 ENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHyqkcQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQ 1864
Cdd:pfam05483 308 SMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAH----SFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIIT 383
|
....*...
gi 4502443 1865 CEIQKKST 1872
Cdd:pfam05483 384 MELQKKSS 391
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
868-1032 |
1.61e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 42.43 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 868 KLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEdelQKAKAISDEmfktykeRDLDFDWHKEKADQLVERWQN 947
Cdd:cd00176 21 ELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALN---ELGEQLIEE-------GHPDAEEIQERLEELNQRWEE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 948 VHVQIDNRLRDLEGIGKSLKYYRDTYHpLDDWIQqvETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQK 1027
Cdd:cd00176 91 LRELAEERRQRLEEALDLQQFFRDADD-LEQWLE--EKEAALASEDLGKDLESVEELLKKHKELEEELEAHEPRLKSLNE 167
|
....*
gi 4502443 1028 YAEQY 1032
Cdd:cd00176 168 LAEEL 172
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1451-1702 |
1.63e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1451 KAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFrdEKELERLQicqRKSDHL 1530
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL--EAELAELE---KEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1531 KEQFEKSHEQLLQNIKA--EKENNDKIQRL--NEELEKSNECAEMLKQKVEELTRQnnetklmMQRIQAESENIVLEKQT 1606
Cdd:COG4942 96 RAELEAQKEELAELLRAlyRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQ-------AEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1607 IQQRCEALKiqadgfkdqlrstnehlhkQTKTEQDFQRKIkcLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNA 1686
Cdd:COG4942 169 LEAERAELE-------------------ALLAELEEERAA--LEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
250
....*....|....*.
gi 4502443 1687 ELNASKEEKRRGEQKV 1702
Cdd:COG4942 228 LIARLEAEAAAAAERT 243
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1253-1461 |
1.63e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1253 EDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDL-AFQKQV--AEKQLKEKQKIELEARRKITEI--- 1326
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELeALQAEIdkLQAEIAEAEAEIEERREELGERara 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1327 QYTCRENALPVCPITQATS----CRAVTGLQQ--EHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSE 1400
Cdd:COG3883 95 LYRSGGSVSYLDVLLGSESfsdfLDRLSALSKiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4502443 1401 EKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASD 1461
Cdd:COG3883 175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
770-1299 |
1.83e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 43.74 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 770 RDDLHESvfrITEQEKLKKELERLKDDLGTITNKCEEFfsqAAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLKTVN 849
Cdd:PRK01156 189 EEKLKSS---NLELENIKKQIADDEKSHSITLKEIERL---SIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAE 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 850 LVLKNTQAAEALVKLYETKL--CEEEAVIADKNNIENLISTLKQwrseVDEKRQVFHALEDELQKAKAISDEMFKTYKER 927
Cdd:PRK01156 263 SDLSMELEKNNYYKELEERHmkIINDPVYKNRNYINDYFKYKND----IENKKQILSNIDAEINKYHAIIKKLSVLQKDY 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 928 DlDFDWHKEKADQLverwqnvhvqiDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVEttqRKIQENQPENSKTLATQLNQ 1007
Cdd:PRK01156 339 N-DYIKKKSRYDDL-----------NNQILELEGYEMDYNSYLKSIESLKKKIEEYS---KNIERMSAFISEILKIQEID 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1008 QKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYR---AMVDSQQKSPVkrrrmqSSADLIIQEFMDLRTRYtal 1084
Cdd:PRK01156 404 PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSrnmEMLNGQSVCPV------CGTTLGEEKSNHIINHY--- 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1085 vtlmtqyikfaGDSLKRLEEEEIKrcketsehgaysdllqrqkaTVLENSKLTGKISELERMVAELKKQKSRVEEELPKV 1164
Cdd:PRK01156 475 -----------NEKKSRLEEKIRE--------------------IEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNK 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1165 REAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLtIEAEAKRAAVEE-----NLLNFR 1239
Cdd:PRK01156 524 IESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISL-IDIETNRSRSNEikkqlNDLESR 602
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502443 1240 NQLEENTF--TRRTLEDHLKRKDLSLNDLEQQKNKL------MEELRRKRDNEEELLKLIKQMEKDLA 1299
Cdd:PRK01156 603 LQEIEIGFpdDKSYIDKSIREIENEANNLNNKYNEIqenkilIEKLRGKIDNYKKQIAEIDSIIPDLK 670
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1090-1593 |
1.87e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.58 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1090 QYIKFAGDSLKR-LEEEEIKRCKETSEHGAYSDLLQRQKA-TVLENSKLTGKISELERMVAElKKQKSRVEEELPKVREA 1167
Cdd:pfam05557 5 IESKARLSQLQNeKKQMELEHKRARIELEKKASALKRQLDrESDRNQELQKRIRLLEKREAE-AEEALREQAELNRLKKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1168 AENELRKQQRN----VEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLE 1243
Cdd:pfam05557 84 YLEALNKKLNEkesqLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1244 ENTFTR---RTLEDHL-------------KRKDLSLNDLEQQKNKLMEELRRKRDN-------EEELLKLIKQMEKDLAF 1300
Cdd:pfam05557 164 SLAEAEqriKELEFEIqsqeqdseivknsKSELARIPELEKELERLREHNKHLNENienklllKEEVEDLKRKLEREEKY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1301 QKQVAEKQLkEKQKIELEARRKITEIQYTCRENALPVcpitqATSCRAVTGLQQEHD-KQKAEELKQQVDELTAANRKAE 1379
Cdd:pfam05557 244 REEAATLEL-EKEKLEQELQSWVKLAQDTGLNLRSPE-----DLSRRIEQLQQREIVlKEENSSLTSSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1380 QDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELER--KDQAEKGYSQQLRELGRQLNQTTGK----AE 1453
Cdd:pfam05557 318 QELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESydKELTMSNYSPQLLERIEEAEDMTQKmqahNE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1454 EAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAE-----KNIQHLNSQIHSFRDEKELERLQICQR--- 1525
Cdd:pfam05557 398 EMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEvdslrRKLETLELERQRLREQKNELEMELERRclq 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1526 --------KSDHL--------KEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNE-CAEMLKQKVEELTRQNNETKL 1588
Cdd:pfam05557 478 gdydpkktKVLHLsmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPEtTSTMNFKEVLDLRKELESAEL 557
|
....*
gi 4502443 1589 MMQRI 1593
Cdd:pfam05557 558 KNQRL 562
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1649-1818 |
2.23e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1649 LEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTI 1728
Cdd:COG4372 15 LFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1729 EEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQ 1808
Cdd:COG4372 95 ELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQ 174
|
170
....*....|
gi 4502443 1809 QYREQMQQGQ 1818
Cdd:COG4372 175 ALSEAEAEQA 184
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1343-1730 |
2.28e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 43.35 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1343 ATSCRAVTglQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNA-------LQLEKTSSEEKARLLKDKLDETNN 1415
Cdd:PLN02939 32 AVSCRARR--RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTslrtvmeLPQKSTSSDDDHNRASMQRDEAIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1416 TLRclKLELERKDQAEKGYSQQLRELGrQLNQTTGKAEEAMQEAsdlkkikRNYQLE-LESLNHEKGKLQREVDRI-TRA 1493
Cdd:PLN02939 110 AID--NEQQTNSKDGEQLSDFQLEDLV-GMIQNAEKNILLLNQA-------RLQALEdLEKILTEKEALQGKINILeMRL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1494 HAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKEN-NDKIQRLNEELEKSNECAEML 1572
Cdd:PLN02939 180 SETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLlKDDIQFLKAELIEVAETEERV 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1573 KQKVEELTRQNNETKLMMQRIQAESENiVLEKQTIQQRCEALKIqaDGFKDQLRSTNEHLHKQTKT---EQDFQRKIKCL 1649
Cdd:PLN02939 260 FKLEKERSLLDASLRELESKFIVAQED-VSKLSPLQYDCWWEKV--ENLQDLLDRATNQVEKAALVldqNQDLRDKVDKL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1650 EEDLAKSQnlVSEFKQKcdqqniIIQNTKKEVRNLNAELNASKEEKrrgEQKVQLQQAQVQELNNRLKKVQDELHLKTIE 1729
Cdd:PLN02939 337 EASLKEAN--VSKFSSY------KVELLQQKLKLLEERLQASDHEI---HSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
|
.
gi 4502443 1730 E 1730
Cdd:PLN02939 406 H 406
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1209-1564 |
2.45e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1209 AAERELERVRQLTIEAE-----AKRAAVEENLLNFRNQLEENTFTRRTLE-------DHLKrkdLSLNDLEQQknklmEE 1276
Cdd:COG3096 277 ANERRELSERALELRRElfgarRQLAEEQYRLVEMARELEELSARESDLEqdyqaasDHLN---LVQTALRQQ-----EK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1277 LRRKRDNEEELlklikqmEKDLAFQKQVAEKqlKEKQKIELEARRKITE------------------------IQYTCRE 1332
Cdd:COG3096 349 IERYQEDLEEL-------TERLEEQEEVVEE--AAEQLAEAEARLEAAEeevdslksqladyqqaldvqqtraIQYQQAV 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1333 NALpvcpiTQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMR---------ELTYELnalqLEKTSSE--- 1400
Cdd:COG3096 420 QAL-----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSvadaarrqfEKAYEL----VCKIAGEver 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1401 ----EKAR-LLKD-----KLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQ 1470
Cdd:COG3096 491 sqawQTAReLLRRyrsqqALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELE 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1471 LELESLNHEKGKLQREVDRITRahavaekNIQHLNSQIHSFRDEKE-LERLQicqrksDHLKEQFEKSHE------QLLQ 1543
Cdd:COG3096 571 EQAAEAVEQRSELRQQLEQLRA-------RIKELAARAPAWLAAQDaLERLR------EQSGEALADSQEvtaamqQLLE 637
|
410 420
....*....|....*....|.
gi 4502443 1544 NIKAEKENNDKIQRLNEELEK 1564
Cdd:COG3096 638 REREATVERDELAARKQALES 658
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
1104-1617 |
2.56e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 43.36 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1104 EEEIKRCKETsehgaYSDLLQRQKATVLENSKLTGK---------ISELERMVAELKKQKSRVEEE-------------- 1160
Cdd:pfam15964 127 EAEVKFCKEE-----LSEMKQRVQVVVLENEKLQQElksqtqeetLREQTLLDSSGNMQNSWCTPEdsrvhqtskrpash 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1161 --LPKVREAAENELRKQQRNVEDISL----QKIRAESEAKQYRRELETIVREKEAAEREL------------ERVRQLTI 1222
Cdd:pfam15964 202 nlAERLKSATTGEDEKWRLELEKLKLlyeaKTEVLESQVKSLRKDLAESQKTCEDLKERLkhkeslvaastsSRVGGLCL 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1223 EAEAKRAAVEENLLNFRNQ-LEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEEL-------LKLIKQM 1294
Cdd:pfam15964 282 KCAQHEAVLAQTHTNVHMQtIERLTKERDDLMSALVSVRSSLAEAQQRESSAYEQVKQAVQMTEEAnfektkaLIQCEQL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1295 EKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALPvcpiTQATSCRAVTGLQQEHDKQKAEELKQQVDELTAA 1374
Cdd:pfam15964 362 KSELERQKERLEKELASQQEKRAQEKEALRKEMKKEREELGA----TMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQ 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1375 NRKAEQDMR------ELTYELNALQLEKTSSEEKARLLKDKLDEtnntlrclklELERKDQAEKGYSQQLRELGRQLNQT 1448
Cdd:pfam15964 438 KQLASQEMDvtkvcgEMRYQLNQTKMKKDEAEKEHREYRTKTGR----------QLEIKDQEIEKLGLELSESKQRLEQA 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1449 TGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAV-AEKNIQHLNSQIHSF-----RDEKELERLQI 1522
Cdd:pfam15964 508 QQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALqAQQREQELTQKMQQMeaqhdKTVNEQYSLLT 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1523 CQ---------------RKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELE----KSNECAEMLKQKVEELTRQN 1583
Cdd:pfam15964 588 SQntfiaklkeecctlaKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEeqcvQHGRMHERMKQRLRQLDKHC 667
|
570 580 590
....*....|....*....|....*....|....
gi 4502443 1584 NETKLMMQRIQAESENIVLEKQTIQQRCEALKIQ 1617
Cdd:pfam15964 668 QATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQ 701
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2446-2476 |
2.59e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 37.46 E-value: 2.59e-03
10 20 30
....*....|....*....|....*....|.
gi 4502443 2446 SPVAGYWLTASGERISVLKASRRNLVDRITA 2476
Cdd:smart00250 8 SAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1608-1817 |
3.34e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 3.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1608 QQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAE 1687
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1688 LNASKEE-----------KRRGEQKVQLQQAQ----------VQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGK 1746
Cdd:COG4942 99 LEAQKEElaellralyrlGRQPPLALLLSPEDfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4502443 1747 FKQSAEEFRKKMEKLMESKVITENDISGirlDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQG 1817
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
1258-1610 |
3.75e-03 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 42.33 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1258 RKDLSLNDLEQQKNKLMEELRRKRD-----NEEELLKLIKQMEKdlafQKQVAEKQLKEKQKIELEARRKITEIQYTCRE 1332
Cdd:pfam15558 18 KEEQRMRELQQQAALAWEELRRRDQkrqetLERERRLLLQQSQE----QWQAEKEQRKARLGREERRRADRREKQVIEKE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1333 NalpvcpitqatSCRAVTGLQQEHDKQKAEELKQQVDELtaaNRKAEQDMRELTYELNALQlektssEEKARLLKDKLDE 1412
Cdd:pfam15558 94 S-----------RWREQAEDQENQRQEKLERARQEAEQR---KQCQEQRLKEKEEELQALR------EQNSLQLQERLEE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1413 TNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQ----EASDLKKIKRNYQLELESLNHEKGKLQREVD 1488
Cdd:pfam15558 154 ACHKRQLKEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRrlslEQSLQRSQENYEQLVEERHRELREKAQKEEE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1489 RITRAHAVAEKniqhlnsqihsfRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNiKAEkenndKIQRLNEELEKSNec 1568
Cdd:pfam15558 234 QFQRAKWRAEE------------KEEERQEHKEALAELADRKIQQARQVAHKTVQD-KAQ-----RARELNLEREKNH-- 293
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 4502443 1569 aEMLKQKVEELTRQNNE-TKLMMQRIQAESENIVLEKQTIQQR 1610
Cdd:pfam15558 294 -HILKLKVEKEEKCHREgIKEAIKKKEQRSEQISREKEATLEE 335
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1199-1427 |
3.91e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.58 E-value: 3.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1199 ELETIVREKEAAEREL--------ERVRQLTIEAEAKRAA--VEENLLNFRNQLEENTFTRRTLE-------DHLKRKDL 1261
Cdd:PLN02939 157 DLEKILTEKEALQGKInilemrlsETDARIKLAAQEKIHVeiLEEQLEKLRNELLIRGATEGLCVhslskelDVLKEENM 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1262 SL-NDLEQQKNKLMEelrrKRDNEEELLKLikqmEKDLAFQKQvAEKQLKEKQKIELEARRKITEIQYTCR----EN--A 1334
Cdd:PLN02939 237 LLkDDIQFLKAELIE----VAETEERVFKL----EKERSLLDA-SLRELESKFIVAQEDVSKLSPLQYDCWwekvENlqD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1335 LPVCPITQATscRAVTGLQQEHDkqkaeeLKQQVDELTAANRKAEQdMRELTYELNALQLEKTSSEEK-----------A 1403
Cdd:PLN02939 308 LLDRATNQVE--KAALVLDQNQD------LRDKVDKLEASLKEANV-SKFSSYKVELLQQKLKLLEERlqasdheihsyI 378
|
250 260
....*....|....*....|....
gi 4502443 1404 RLLKDKLDETNNTLRCLKLELERK 1427
Cdd:PLN02939 379 QLYQESIKEFQDTLSKLKEESKKR 402
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1518-1732 |
4.06e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 4.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1518 ERLQICQRKSDHLKEQFeKSHEQLLQNIkaEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQ------------NNE 1585
Cdd:PHA02562 181 QQIQTLDMKIDHIQQQI-KTYNKNIEEQ--RKKNGENIARKQNKYDELVEEAKTIKAEIEELTDEllnlvmdiedpsAAL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1586 TKLMMQRIQAES-------ENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQN 1658
Cdd:PHA02562 258 NKLNTAAAKIKSkieqfqkVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSK 337
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1659 LVSEFKQKCDQQNIIIQNTKKEVRNLNAEL-NASKEEKRRGEQKVQLQQaQVQELNNRLKKVQDELHLKTIEEQM 1732
Cdd:PHA02562 338 KLLELKNKISTNKQSLITLVDKAKKVKAAIeELQAEFVDNAEELAKLQD-ELDKIVKTKSELVKEKYHRGIVTDL 411
|
|
| Nup88 |
pfam10168 |
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ... |
1630-1734 |
4.91e-03 |
|
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.
Pssm-ID: 462975 [Multi-domain] Cd Length: 713 Bit Score: 42.34 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1630 EHLHKQTKTEQDFQRKIKCLE----------EDLAKSQNLVSE--------FKQKCDQQNIIIQNTKKEVRNLNAELNAS 1691
Cdd:pfam10168 547 EYLKKHDLAREEIQKRVKLLKlqkeqqlqelQSLEEERKSLSEraeklaekYEEIKDKQEKLMRRCKKVLQRLNSQLPVL 626
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 4502443 1692 KEEKRRGEQKVQLQQAQVQELNNRLKKVQdelhlKTIEEQMTH 1734
Cdd:pfam10168 627 SDAEREMKKELETINEQLKHLANAIKQAK-----KKMNYQRYQ 664
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1103-1846 |
4.96e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 4.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1103 EEEEIKRcKETS---EHGAYSDLLQRqkatVLENSKLTGKIselERMVAELKKQKSRVEEELPKVREAAE----NELRKQ 1175
Cdd:PRK04863 315 ELAELNE-AESDleqDYQAASDHLNL----VQTALRQQEKI---ERYQADLEELEERLEEQNEVVEEADEqqeeNEARAE 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1176 QRNVEDISLQK---------IRAESEAKQYRReletivrekeaAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENT 1246
Cdd:PRK04863 387 AAEEEVDELKSqladyqqalDVQQTRAIQYQQ-----------AVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEAT 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1247 FTRRTLEDHLK----------------RK---DLSLNDLEQQKNKLMEELRRKR---DNEEELLKLIKQMEKDLAfQKQV 1304
Cdd:PRK04863 456 EELLSLEQKLSvaqaahsqfeqayqlvRKiagEVSRSEAWDVARELLRRLREQRhlaEQLQQLRMRLSELEQRLR-QQQR 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1305 AEKQLKEKQK----------------IELEARRK-ITEIQYTCREnalpvcpitQATSCRAvtglQQEHDKQKAEELKQQ 1367
Cdd:PRK04863 535 AERLLAEFCKrlgknlddedeleqlqEELEARLEsLSESVSEARE---------RRMALRQ----QLEQLQARIQRLAAR 601
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1368 VDELTAANRKAEQ----------DMRELTyELNALQLEKtssEEKARLLKDKLDETNntlRCLKLELERKDQAEKGYSQQ 1437
Cdd:PRK04863 602 APAWLAAQDALARlreqsgeefeDSQDVT-EYMQQLLER---ERELTVERDELAARK---QALDEEIERLSQPGGSEDPR 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1438 LRELGRQLNQ---TTGKAEEAMQEA----------------SDLKKIKRnyQLE-----------------------LES 1475
Cdd:PRK04863 675 LNALAERFGGvllSEIYDDVSLEDApyfsalygparhaivvPDLSDAAE--QLAgledcpedlyliegdpdsfddsvFSV 752
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1476 LNHEKGKLQREVDRITR----------AHAVAEKNIQHLNSQIHSF--RDEKELERLQICQRKSDHLkEQFEKSHEQLLQ 1543
Cdd:PRK04863 753 EELEKAVVVKIADRQWRysrfpevplfGRAAREKRIEQLRAEREELaeRYATLSFDVQKLQRLHQAF-SRFIGSHLAVAF 831
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1544 NIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELtRQNNETKLMMQRIQAESEniVLEKQTIQQRCEALKIQ------ 1617
Cdd:PRK04863 832 EADPEAELRQLNRRRVELERALADHESQEQQQRSQL-EQAKEGLSALNRLLPRLN--LLADETLADRVEEIREQldeaee 908
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1618 ADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDqqniiiqnTKKEVRNLNAELNASKEEKRR 1697
Cdd:PRK04863 909 AKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAF--------ALTEVVQRRAHFSYEDAAEML 980
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1698 GEqkvqlQQAQVQELNNRLKKVQDEL-----HLKTIEEQMTHRKMVLFQEESgkfkqsaeEFRKKMEKLMESKviTENDI 1772
Cdd:PRK04863 981 AK-----NSDLNEKLRQRLEQAEQERtrareQLRQAQAQLAQYNQVLASLKS--------SYDAKRQMLQELK--QELQD 1045
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4502443 1773 SGIRLDFVSLQQENSRAQE-NAKL--CETNIKELERQLQQYREQMQqgqhmeaNHYQKCQKLEDELIAQKREVENLK 1846
Cdd:PRK04863 1046 LGVPADSGAEERARARRDElHARLsaNRSRRNQLEKQLTFCEAEMD-------NLTKKLRKLERDYHEMREQVVNAK 1115
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1557-1861 |
5.08e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 5.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1557 RLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQT 1636
Cdd:COG4372 14 SLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1637 KTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRL 1716
Cdd:COG4372 94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1717 KKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLC 1796
Cdd:COG4372 174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1797 ETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLV 1861
Cdd:COG4372 254 EVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALL 318
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1266-1722 |
5.18e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.06 E-value: 5.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1266 LEQQKNKLMEELRRKRDNEEEL-LKLIKQMEKDLAfQKQVAEKQLKEKQKIELEARRKITEIQytcrenalpvcpitqat 1344
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELnLKELKELEEELK-EAEEKEEEYAELQEELEELEEELEELE----------------- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1345 scRAVTGLQQEHDKQkaeELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEE---KARLLKDKLDETNNTL-RCL 1420
Cdd:COG4717 109 --AELEELREELEKL---EKLLQLLPLYQELEALEAELAELPERLEELEERLEELREleeELEELEAELAELQEELeELL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1421 KLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEK-------------------G 1481
Cdd:COG4717 184 EQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliaaallallG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1482 KLQREVDRITRAHAVA--------------EKNIQHLNSQIHSFRDEKELERLQicQRKSDHLKEQFEKSHEQLLQNIKA 1547
Cdd:COG4717 264 LGGSLLSLILTIAGVLflvlgllallflllAREKASLGKEAEELQALPALEELE--EEELEELLAALGLPPDLSPEELLE 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1548 EKENNDKIQRLNEELEKSNecaemlkqkvEELTRQNNETKL--MMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQL 1625
Cdd:COG4717 342 LLDRIEELQELLREAEELE----------EELQLEELEQEIaaLLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQL 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1626 RSTNEHLHKQ--TKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQN--TKKEVRNLNAELNASKEEKRRGEQK 1701
Cdd:COG4717 412 EELLGELEELleALDEEELEEELEELEEELEELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEE 491
|
490 500
....*....|....*....|.
gi 4502443 1702 VQLQQAQVQELNNRLKKVQDE 1722
Cdd:COG4717 492 WAALKLALELLEEAREEYREE 512
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
1194-1488 |
7.33e-03 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 40.78 E-value: 7.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1194 KQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAveenlLNFRNQLeentftrrtLEDHLKRKdlslNDLEQQKNKL 1273
Cdd:pfam00261 4 QQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAA-----LNRRIQL---------LEEELERT----EERLAEALEK 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1274 MEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIqytcrenalpvcpitqatscravtglq 1353
Cdd:pfam00261 66 LEEAEKAADESERGRKVLENRALKDEEKMEILEAQLKEAKEIAEEADRKYEEV--------------------------- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1354 qehdkqkAEELKQQVDELTAANRKAEQdmreltyelnalqlektsSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKG 1433
Cdd:pfam00261 119 -------ARKLVVVEGDLERAEERAEL------------------AESKIVELEEELKVVGNNLKSLEASEEKASEREDK 173
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 4502443 1434 YSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVD 1488
Cdd:pfam00261 174 YEEQIRFLTEKLKEAETRAEFAERSVQKLEKEVDRLEDELEAEKEKYKAISEELD 228
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1547-1871 |
8.51e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 8.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1547 AEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNEtklMMQRIQAESENIVLEKQTiqqRCEALkiqadgfkdqlr 1626
Cdd:PLN02939 94 DDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLED---LVGMIQNAEKNILLLNQA---RLQAL------------ 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1627 stnEHLHKQTKTEQDFQRKIKCLEEDLAKSqnlvSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQ 1706
Cdd:PLN02939 156 ---EDLEKILTEKEALQGKINILEMRLSET----DARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKEL 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1707 AQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEfrkkmeklMESKVI-TENDISGIrldfVSLQQE 1785
Cdd:PLN02939 229 DVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRE--------LESKFIvAQEDVSKL----SPLQYD 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1786 ----------------NSRAQENAKLCETNiKELERQLQQYREQMQQGQHMEANHY------QKCQKLEDELIAQKREVE 1843
Cdd:PLN02939 297 cwwekvenlqdlldraTNQVEKAALVLDQN-QDLRDKVDKLEASLKEANVSKFSSYkvellqQKLKLLEERLQASDHEIH 375
|
330 340
....*....|....*....|....*...
gi 4502443 1844 NLKQKMDQQIKEHEHQLVLLQCEIQKKS 1871
Cdd:PLN02939 376 SYIQLYQESIKEFQDTLSKLKEESKKRS 403
|
|
| PLEC |
smart00250 |
Plectin repeat; |
2337-2366 |
8.61e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 36.31 E-value: 8.61e-03
10 20 30
....*....|....*....|....*....|
gi 4502443 2337 HRISVVDTKTGSELTVYEAFQRNLIEKSIY 2366
Cdd:smart00250 9 AIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1355-1845 |
8.63e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.56 E-value: 8.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1355 EHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGY 1434
Cdd:PRK02224 247 EERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 SQQLRELGRQLNQTTGKAEEAMQEASDLKKikrnyqlELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDE 1514
Cdd:PRK02224 327 RDRLEECRVAAQAHNEEAESLREDADDLEE-------RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1515 KEL--ERLQICQRKSDHLKEQFEKSHEQlLQNIKAEKENNDKIQRLNEELEKSNECAEmLKQKVEELTRQN--NETKLMM 1590
Cdd:PRK02224 400 FGDapVDLGNAEDFLEELREERDELRER-EAELEATLRTARERVEEAEALLEAGKCPE-CGQPVEGSPHVEtiEEDRERV 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1591 QRIQAESENIVLEKQTIQQRCEALKiqadgfkdqlrstnehlhKQTKTEQDFQRkikcLEEDLAKSQNLVSEFKQKCDQQ 1670
Cdd:PRK02224 478 EELEAELEDLEEEVEEVEERLERAE------------------DLVEAEDRIER----LEERREDLEELIAERRETIEEK 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1671 NIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELH-LKTIEEQMTHR-----KMVLFQEES 1744
Cdd:PRK02224 536 RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIEsLERIRTLLAAIadaedEIERLREKR 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1745 GKFKQSAEEFRKKMEKLMESKVITENDISGIRLDfvSLQQENSRAQENAKLCETNIKELERQlqqyREQMQQGQHMEANH 1824
Cdd:PRK02224 616 EALAELNDERRERLAEKRERKRELEAEFDEARIE--EAREDKERAEEYLEQVEEKLDELREE----RDDLQAEIGAVENE 689
|
490 500
....*....|....*....|.
gi 4502443 1825 YQKCQKLEDELIAQKREVENL 1845
Cdd:PRK02224 690 LEELEELRERREALENRVEAL 710
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1471-1591 |
8.69e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.61 E-value: 8.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1471 LELESLNHEKGKLQREVDRITRAHAVAEKNiqhlnsqihsfRDEKELERLQICQRKSDHLKEQFEksheQLLQNIKAEKE 1550
Cdd:COG0542 404 MEIDSKPEELDELERRLEQLEIEKEALKKE-----------QDEASFERLAELRDELAELEEELE----ALKARWEAEKE 468
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 4502443 1551 NNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQ 1591
Cdd:COG0542 469 LIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLR 509
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1361-1697 |
8.71e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 41.58 E-value: 8.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1361 AEELKQQVDELTAANRKAEQD-MRELTYELNALQlEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGY----- 1434
Cdd:PRK10929 25 EKQITQELEQAKAAKTPAQAEiVEALQSALNWLE-ERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVppnms 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1435 -----------SQQLRELGRQLNQTTGKAEEAM-------QEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAV 1496
Cdd:PRK10929 104 tdaleqeilqvSSQLLEKSRQAQQEQDRAREISdslsqlpQQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1497 AEK-NIQHLNSQIHSFRDEKELERLQIcqrksdhlkEQFEKSHEQLLQNIKAEKeNNDKIQRlNEELEKSNECAEMLKQK 1575
Cdd:PRK10929 184 ALKaLVDELELAQLSANNRQELARLRS---------ELAKKRSQQLDAYLQALR-NQLNSQR-QREAERALESTELLAEQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1576 VEELT-------RQNNETKLMMQRiQAESENIVLEKQ------TIQQR-------------------CEALKIQA----- 1618
Cdd:PRK10929 253 SGDLPksivaqfKINRELSQALNQ-QAQRMDLIASQQrqaasqTLQVRqalntlreqsqwlgvsnalGEALRAQVarlpe 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1619 -------DGFKDQLRSTN-------EHLHKQTKTEQDF-------QRKIkcLEEDLAKSQNLVSEFKQKCDQQniIIQNT 1677
Cdd:PRK10929 332 mpkpqqlDTEMAQLRVQRlryedllNKQPQLRQIRQADgqpltaeQNRI--LDAQLRTQRELLNSLLSGGDTL--ILELT 407
|
410 420
....*....|....*....|..
gi 4502443 1678 KKEVRN--LNAELNASKEEKRR 1697
Cdd:PRK10929 408 KLKVANsqLEDALKEVNEATHR 429
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
1205-1405 |
8.84e-03 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 41.48 E-value: 8.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1205 REKEAAEREL---ERVRQLTIEAEAKRAAVEENllnfrnqleentftRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKR 1281
Cdd:pfam15709 328 REQEKASRDRlraERAEMRRLEVERKRREQEEQ--------------RRLQQEQLERAEKMREELELEQQRRFEEIRLRK 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502443 1282 DNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKielEARRKITEIQYTcrenalpvcpitqatscravtglQQEHDKQKA 1361
Cdd:pfam15709 394 QRLEEERQRQEEEERKQRLQLQAAQERARQQQE---EFRRKLQELQRK-----------------------KQQEEAERA 447
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 4502443 1362 EELKQQVDELT---AANRKAEQDMREltYELNALQLEKTSSEEKARL 1405
Cdd:pfam15709 448 EAEKQRQKELEmqlAEEQKRLMEMAE--EERLEYQRQKQEAEEKARL 492
|
|
|