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Conserved domains on  [gi|1491609464|ref|NP_001956|]
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early growth response protein 4 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11986654)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  22803940|11361095|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
408-466 1.19e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.19e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1491609464 408 KPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSD--EKKRHSKVHLKQKAR 466
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplELSRHLRTHHNNPSD 92
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 380-404 4.05e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


:

Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 4.05e-03
                          10        20
                  ....*....|....*....|....*
gi 1491609464 380 FACPVesCVRSFARSDELNRHLRIH 404
Cdd:pfam00096   1 YKCPD--CGKSFSRKSNLKRHLRTH 23
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 74-339 4.73e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464   74 PTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAP 153
Cdd:PHA03247  2720 PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  154 FPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDavsafKGPYAPWELLSVG-APGncgsqGDYQAAPEAR 232
Cdd:PHA03247  2800 SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP-----PGPPPPSLPLGGSvAPG-----GDVRRRPPSR 2869

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  233 FPVigtkiedllsiSCPAELPAVPANRL---YPSGAYDAFPLAPgdlgegaEGLPGLLTPPSGEGGSSGDGGEFLASTQP 309
Cdd:PHA03247  2870 SPA-----------AKPAAPARPPVRRLarpAVSRSTESFALPP-------DQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270
                   ....*....|....*....|....*....|
gi 1491609464  310 QLSPLGLRSAAAAdfPKPLVADIPGSSGVA 339
Cdd:PHA03247  2932 PPPPPPRPQPPLA--PTTDPAGAGEPSGAV 2959
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
408-466 1.19e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.19e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1491609464 408 KPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSD--EKKRHSKVHLKQKAR 466
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplELSRHLRTHHNNPSD 92
zf-H2C2_2 pfam13465
Zinc-finger double domain;
424-449 2.12e-07

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 46.98  E-value: 2.12e-07
                          10        20
                  ....*....|....*....|....*.
gi 1491609464 424 HLTTHVRTHTGEKPFACDVCGRRFAR 449
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 409-456 1.86e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 1.86e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1491609464 409 PFQCRICLRNFSRSDHLTTHVRTHTGEKpfACDVCGRRFARSDEKKRH 456
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 380-404 4.05e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 4.05e-03
                          10        20
                  ....*....|....*....|....*
gi 1491609464 380 FACPVesCVRSFARSDELNRHLRIH 404
Cdd:pfam00096   1 YKCPD--CGKSFSRKSNLKRHLRTH 23
PHA03247 PHA03247
large tegument protein UL36; Provisional
 74-339 4.73e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464   74 PTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAP 153
Cdd:PHA03247  2720 PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  154 FPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDavsafKGPYAPWELLSVG-APGncgsqGDYQAAPEAR 232
Cdd:PHA03247  2800 SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP-----PGPPPPSLPLGGSvAPG-----GDVRRRPPSR 2869

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  233 FPVigtkiedllsiSCPAELPAVPANRL---YPSGAYDAFPLAPgdlgegaEGLPGLLTPPSGEGGSSGDGGEFLASTQP 309
Cdd:PHA03247  2870 SPA-----------AKPAAPARPPVRRLarpAVSRSTESFALPP-------DQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270
                   ....*....|....*....|....*....|
gi 1491609464  310 QLSPLGLRSAAAAdfPKPLVADIPGSSGVA 339
Cdd:PHA03247  2932 PPPPPPRPQPPLA--PTTDPAGAGEPSGAV 2959
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
408-466 1.19e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.19e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1491609464 408 KPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSD--EKKRHSKVHLKQKAR 466
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplELSRHLRTHHNNPSD 92
zf-H2C2_2 pfam13465
Zinc-finger double domain;
424-449 2.12e-07

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 46.98  E-value: 2.12e-07
                          10        20
                  ....*....|....*....|....*.
gi 1491609464 424 HLTTHVRTHTGEKPFACDVCGRRFAR 449
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
383-438 1.77e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 50.46  E-value: 1.77e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1491609464 383 PVESCVRSFARSDELNRHLRIHTGHKPFQCR--ICLRNFSRSDHLTTHVRTHTGEKPF 438
Cdd:COG5048    35 SCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSD 92
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
408-468 5.27e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.92  E-value: 5.27e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1491609464 408 KPFQCRICLRNFSRSDHLTTHVRT--HTGE--KPFACDV--CGRRFARSDEKKRHSKVHLKQKARAE 468
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKE 354
zf-H2C2_2 pfam13465
Zinc-finger double domain;
396-421 6.28e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 6.28e-06
                          10        20
                  ....*....|....*....|....*.
gi 1491609464 396 ELNRHLRIHTGHKPFQCRICLRNFSR 421
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
382-464 1.06e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.77  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464 382 CPVESCVRSFARSDELNRHLR--IHTG--HKPFQCRI--CLRNFSRSDHLTTHVRTHTGEKPFAC--DVCGRRFARSDEK 453
Cdd:COG5048   290 IKSKQCNISFSRSSPLTRHLRsvNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNN 369

                          90
                  ....*....|.
gi 1491609464 454 KRHSKVHLKQK 464
Cdd:COG5048   370 EPPQSLQQYKD 380
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 410-432 8.18e-05

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 8.18e-05
                          10        20
                  ....*....|....*....|...
gi 1491609464 410 FQCRICLRNFSRSDHLTTHVRTH 432
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2_4 pfam13894
C2H2-type zinc finger; This family contains a number of divergent C2H2 type zinc fingers.
 410-432 1.65e-03

C2H2-type zinc finger; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464025  Cd Length: 24  Bit Score: 35.70  E-value: 1.65e-03
                          10        20
                  ....*....|....*....|...
gi 1491609464 410 FQCRICLRNFSRSDHLTTHVRTH 432
Cdd:pfam13894   1 FKCPICGKSFSSKKSLKRHLKTH 23
PHA00733 PHA00733
hypothetical protein
 409-456 1.86e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.32  E-value: 1.86e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1491609464 409 PFQCRICLRNFSRSDHLTTHVRTHTGEKpfACDVCGRRFARSDEKKRH 456
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
380-456 2.72e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 40.00  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464 380 FACPVESCVRSFARSDELNRHLRIHtgHKPFQCRICLRN---------FSRSDHLTTHVRTHTGEKPFA----CDVCGRR 446
Cdd:COG5236   152 FKCPKSKCHRRCGSLKELKKHYKAQ--HGFVLCSECIGNkkdfwneirLFRSSTLRDHKNGGLEEEGFKghplCIFCKIY 229

                          90
                  ....*....|
gi 1491609464 447 FARSDEKKRH 456
Cdd:COG5236   230 FYDDDELRRH 239
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 380-404 4.05e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 4.05e-03
                          10        20
                  ....*....|....*....|....*
gi 1491609464 380 FACPVesCVRSFARSDELNRHLRIH 404
Cdd:pfam00096   1 YKCPD--CGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 438-460 4.34e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.58  E-value: 4.34e-03
                          10        20
                  ....*....|....*....|...
gi 1491609464 438 FACDVCGRRFARSDEKKRHSKVH 460
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
PHA03247 PHA03247
large tegument protein UL36; Provisional
 74-339 4.73e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464   74 PTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAP 153
Cdd:PHA03247  2720 PLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  154 FPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDavsafKGPYAPWELLSVG-APGncgsqGDYQAAPEAR 232
Cdd:PHA03247  2800 SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP-----PGPPPPSLPLGGSvAPG-----GDVRRRPPSR 2869

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  233 FPVigtkiedllsiSCPAELPAVPANRL---YPSGAYDAFPLAPgdlgegaEGLPGLLTPPSGEGGSSGDGGEFLASTQP 309
Cdd:PHA03247  2870 SPA-----------AKPAAPARPPVRRLarpAVSRSTESFALPP-------DQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270
                   ....*....|....*....|....*....|
gi 1491609464  310 QLSPLGLRSAAAAdfPKPLVADIPGSSGVA 339
Cdd:PHA03247  2932 PPPPPPRPQPPLA--PTTDPAGAGEPSGAV 2959
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
112-333 6.53e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.09  E-value: 6.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464 112 APFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAfweASPCAGApsqcLYEPQLSPPDVKPGLRAPPA 191
Cdd:PRK12323  380 APVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPAR---RSPAPEA----LAAARQASARGPGGAPAPAP 452

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464 192 SPAldAVSAFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKIEDL---LSISCPAELPAVPANRLYPSGAYDA 268
Cdd:PRK12323  453 APA--AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELppeFASPAPAQPDAAPAGWVAESIPDPA 530

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1491609464 269 FPLAPGDLGEGAEGLPGLLTPPsgeggSSGDGGEFLASTQPQLSPLGLRSAAAADFPKpLVADIP 333
Cdd:PRK12323  531 TADPDDAFETLAPAPAAAPAPR-----AAAATEPVVAPRPPRASASGLPDMFDGDWPA-LAARLP 589
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
25-207 8.71e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 38.68  E-value: 8.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464  25 PSAELPRLPARDAPAATGYPGAGDFLSWALNSCGASGDLADscflegpAPTPPPGlsysgsffIQAVPEHPHDPEAlfnl 104
Cdd:PRK07003  368 PGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGA-------ALAPKAA--------AAAAATRAEAPPA---- 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1491609464 105 msgilglAPFPGPEAAASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPqlSPPDVKP 184
Cdd:PRK07003  429 -------APAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEP--APRAAAP 499

                         170       180
                  ....*....|....*....|...
gi 1491609464 185 GLRAPPASPALDAVSAFKGPYAP 207
Cdd:PRK07003  500 SAATPAAVPDARAPAAASREDAP 522
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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