|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
39-353 |
1.08e-123 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 358.80 E-value: 1.08e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGpELFRLRVLELNASDERGIQV 118
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG-EDWRENFLELNASDERGIDV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 119 VREKVKNFAQLTVSGSrsdgkpcPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFR 198
Cdd:PRK00440 85 IRNKIKEFARTAPVGG-------APFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 199 FKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLtgGKEITEKVITDIAGVIPAEKIDGVF 278
Cdd:PRK00440 158 FSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAAT--GKEVTEEAVYKITGTARPEEIREMI 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 279 AACQSGSFDKLEAVVKDL-IDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCA 353
Cdd:PRK00440 236 ELALNGDFTEAREKLRDLmIDYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLA 311
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
38-353 |
6.90e-83 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 255.04 E-value: 6.90e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 38 VPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPeLFRLRVLELNASDERGIQ 117
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGP-NYKEAVLELNASDDRGID 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 118 VVREKVKNFAQLTVSgsrsdgkpCPP--FKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCS 195
Cdd:PLN03025 80 VVRNKIKMFAQKKVT--------LPPgrHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 196 KFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQsATRLTGG---KEITEKVITDiagviPAE 272
Cdd:PLN03025 152 IVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQ-ATHSGFGfvnQENVFKVCDQ-----PHP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 273 K-IDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKsiiTEKLAEVDKC---LADGADEHLQL 348
Cdd:PLN03025 226 LhVKNIVRNCLKGKFDDACDGLKQLYDLGYSPTDIITTLFRVVKNYDMPEFLK---LEYLREIGFAhmrICDGVGSLLQL 302
|
....*
gi 4506491 349 ISLCA 353
Cdd:PLN03025 303 SGLLA 307
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
40-354 |
1.22e-69 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 221.40 E-value: 1.22e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 40 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGpELFRLRVLELNASD--ERGIQ 117
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYG-DPWENNFTEFNVADffDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 118 VVREKvKNFAQLTVSGSRS---------------------DGkpcpPFKIVILDEADSMTSAAQAALRRTMEKESKTTRF 176
Cdd:PRK12402 84 YLVED-PRFAHFLGTDKRIrsskidnfkhvlkeyasyrplSA----DYKTILLDNAEALREDAQQALRRIMEQYSRTCRF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 177 CLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGgkE 256
Cdd:PRK12402 159 IIATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAG--E 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 257 ITEKVITDIAGVIPA-EKIDGVFAACQSGSFDKLEAVVKDL-IDEGHAATQLVNQLHDVVVENNLSDKQKSIITeKLAEV 334
Cdd:PRK12402 237 ITMEAAYEALGDVGTdEVIESLLDAAEAGDFTDARKTLDDLlIDEGLSGGEVLEELLRVARSRYRGDNLARLHR-LAADA 315
|
330 340
....*....|....*....|
gi 4506491 335 DKCLADGADEHLQLISLCAT 354
Cdd:PRK12402 316 DARLTDGANDRIQLEALLAE 335
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
85-353 |
8.91e-59 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 203.92 E-value: 8.91e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 85 TSTILAAARELFGpELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcPPFKIVILDEADSMTSAAQAALR 164
Cdd:PRK04132 580 TTAALALARELFG-ENWRHNFLELNASDERGINVIREKVKEFARTKPIGG-------ASFKIIFLDEADALTQDAQQALR 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 165 RTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITF 244
Cdd:PRK04132 652 RTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINI 731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 245 LQSATRLTggKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKL-EAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQ 323
Cdd:PRK04132 732 LQAAAALD--DKITDENVFLVASRARPEDIREMMLLALKGNFLKArEKLREILLKQGLSGEDVLVQMHREVFNLPIDEPK 809
|
250 260 270
....*....|....*....|....*....|
gi 4506491 324 KSIITEKLAEVDKCLADGADEHLQLISLCA 353
Cdd:PRK04132 810 KVELADKIGEYNFRLVEGANEMIQLEALLA 839
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
55-353 |
5.09e-50 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 169.00 E-value: 5.09e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 55 QEEVVAVLKKSLEGADLP-NLLFYGPPGTGKTSTILAAARELFG-------------PELFRLR----VLELNA---SDE 113
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPhALLLHGPPGIGKTTLALALARDLLCenpeggkacgqchSRLMAAGnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 114 RGIQVVREkVKNFAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSR 193
Cdd:COG0470 81 IGIDQIRE-LGEFLSLTPLEGG--------RKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 194 CSKFRFKPLSDKIQQQRLldiaKKENVkiSDEGIAYLVKVSEGDLRKAITFLQsatRLTGGKEITEKVITDIAGVIPAEK 273
Cdd:COG0470 152 CQVIRFRPPSEEEALAWL----REEGV--DEDALEAILRLAGGDPRAAINLLQ---ALAGRKELLEDLAALLSRDRALEL 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 274 IDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLhdvvvennlsdkqksiitEKLAEVDKCLADGADEHLQLISLCA 353
Cdd:COG0470 223 LDALLKAEALELLDWLLKWLLDNLPLEYAGEDLARAY------------------EALSEADRRLGRYANDRLLLEALLA 284
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
40-356 |
1.54e-42 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 150.53 E-value: 1.54e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 40 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGP-PGTGKTSTILAAARELfGPElfrlrVLELNASDERgIQV 118
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEV-GAE-----VLFVNGSDCR-IDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 119 VREKVKNFAQlTVSgsrsdgkPCPPFKIVILDEAD-SMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKF 197
Cdd:PHA02544 84 VRNRLTRFAS-TVS-------LTGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 198 RF-KPLSDK---IQQQ---RLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQsatRLTGGKEITEKVITDIAGvip 270
Cdd:PHA02544 156 DFgVPTKEEqieMMKQmivRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQ---RYASTGKIDAGILSEVTN--- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 271 aEKIDGVFAACQSGSFDKLEAVVKDLIDEGhaaTQLVNQLHDVVVEnnlSDKQKSII--TEKLAEVDKCLADGADEHLQL 348
Cdd:PHA02544 230 -SDIDDVVEALKAKDFKAVRALAPNYANDY---ASFVGKLYDELYP---QVTPPSIIrlIEIIGENNQYHGFAADQEIHL 302
|
....*...
gi 4506491 349 ISLCATVM 356
Cdd:PHA02544 303 LYLLTQLM 310
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
37-259 |
2.67e-36 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 137.36 E-value: 2.67e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 37 PVPWVEKYRPKCVDEVAFQEEVVAVLKKSLE----GADLPNLLFYGPPGTGKTSTILAAARElfgpelFRLRVLELNASD 112
Cdd:PRK04195 1 MMPWVEKYRPKTLSDVVGNEKAKEQLREWIEswlkGKPKKALLLYGPPGVGKTSLAHALAND------YGWEVIELNASD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 113 ERGIQVVREKVKNFAQL-TVSGSRSdgkpcppfKIVILDEADSM-----TSAAQAALRRTmekesKTTRFCLIC---NYV 183
Cdd:PRK04195 75 QRTADVIERVAGEAATSgSLFGARR--------KLILLDEVDGIhgnedRGGARAILELI-----KKAKQPIILtanDPY 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATrlTGGKEITE 259
Cdd:PRK04195 142 DPSLRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIA--EGYGKLTL 215
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
46-362 |
3.92e-29 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 114.90 E-value: 3.92e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 46 PKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA-----RELFGP--------ELFRLR---VL 106
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLarILAKAlncenGPTGEPcgecescrAIAAGShpdVI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 107 EL--NASdERGIQVVREKVKNFAQLTVSGsrsdgkpcpPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVS 184
Cdd:COG2812 86 EIdaEAS-NIGVDDIRELIEKVSYAPVEG---------RYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 185 RIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSAtrltggkeitekvitD 264
Cdd:COG2812 156 KLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQA---------------I 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 265 IAGVIPA-EKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQL----HDVVVENNLSDKQKSIITEKLAEVDKcLA 339
Cdd:COG2812 221 AFGLLDRrELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLlsllRDLLLLKLGPDAELLVNEDERERLQE-LA 299
|
330 340
....*....|....*....|....*
gi 4506491 340 D--GADEHLQLISLCATVMQQLSQN 362
Cdd:COG2812 300 RrlSPERLLRAIQILLEARRELERN 324
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
43-316 |
2.49e-28 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 114.86 E-value: 2.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA-----RELFGP-----------ELFRL 103
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVarILAKSlncenRKGVEPcnecracrsidEGTFM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVReKVKNfaqlTVSGSRSDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK14962 87 DVIELDAASNRGIDEIR-KIRD----AVGYRPMEGK----YKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITEKVIT 263
Cdd:PRK14962 158 EKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGK-ITLETVH 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 4506491 264 DIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVE 316
Cdd:PRK14962 237 EALGLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVE 289
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
38-314 |
1.69e-26 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 109.91 E-value: 1.69e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 38 VPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELFGPELFR------------ 102
Cdd:PRK14953 4 IPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHaYIFAGPRGTGKTTIarILAKVLNCLNPQEGEpcgkcencveid 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 ----LRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCL 178
Cdd:PRK14953 84 kgsfPDLIEIDAASNRGIDDIRALRDAVSYTPIKGK---------YKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 179 ICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeIT 258
Cdd:PRK14953 155 CTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGK-VT 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 259 EKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVV 314
Cdd:PRK14953 234 IKVVEEFLGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEI 289
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
40-316 |
2.55e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 110.29 E-value: 2.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 40 WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA------RELFGP-----ELFR--L 103
Cdd:PRK07133 8 LYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVakIFANAlncshkTDLLEPcqeciENVNnsL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVR---EKVKNFAQLTvsgsrsdgkpcpPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
Cdd:PRK07133 88 DIIEMDAASNNGVDEIReliENVKNLPTQS------------KYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILAT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 181 NYVSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeIT 258
Cdd:PRK07133 156 TEVHKI--PLTilSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNK-IT 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 259 EKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVE 316
Cdd:PRK07133 233 LKNVEELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKE 290
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
42-267 |
9.42e-26 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 106.71 E-value: 9.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 42 EKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTSTILAAARElfgpelFRLRVLELNASDErGIQV 118
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLGpgkPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGA------TDAPFEALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 119 VREKVKNFAQLTVSGSRsdgkpcppfKIVILDEADSMTSAAQAALRRTMEKES-----KTTR---FclicnyvsRIIEPL 190
Cdd:PRK13342 77 LREVIEEARQRRSAGRR---------TILFIDEIHRFNKAQQDALLPHVEDGTitligATTEnpsF--------EVNPAL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 191 TSRCSKFRFKPLSDK-IQQ--QRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLtgGKEITEKVITDIAG 267
Cdd:PRK13342 140 LSRAQVFELKPLSEEdIEQllKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAALG--VDSITLELLEEALQ 217
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
269-353 |
2.08e-25 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 97.93 E-value: 2.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 269 IPAEKIDGVFAACQSGSFDKLEAVVK-DLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQ 347
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVReLLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*.
gi 4506491 348 LISLCA 353
Cdd:pfam08542 81 LSALLA 86
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
55-201 |
2.13e-23 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 94.52 E-value: 2.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 55 QEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPelfRLRVLELNASDERGIQVVREKVKNFAQLTVSGS 134
Cdd:cd00009 3 QEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRP---GAPFLYLNASDLLEGLVVAELFGHFLVRLLFEL 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 135 RSDGKPCppfkIVILDEADSMTSAAQAALRRTMEKESKTT------RFCLICNYVS--RIIEPLTSRC-SKFRFKP 201
Cdd:cd00009 80 AEKAKPG----VLFIDEIDSLSRGAQNALLRVLETLNDLRidrenvRVIGATNRPLlgDLDRALYDRLdIRIVIPL 151
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
42-310 |
4.24e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 100.30 E-value: 4.24e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 42 EKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELFGP--------ELFRL------- 103
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHaYLFSGPRGVGKTTTarLIAMAVNCSGEdpkpcgecESCLAvrrgahp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVREKVKNFAQLTVSGSRsdgkpcppfKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK14963 86 DVLEIDAASNNSVEDVRDLREKVLLAPLRGGR---------KVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSAtrLTGGKEITEKVIT 263
Cdd:PRK14963 157 EKMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERL--LALGTPVTRKQVE 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 4506491 264 DIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQL 310
Cdd:PRK14963 235 EALGLPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGL 281
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
43-269 |
1.61e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 94.17 E-value: 1.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELFGP------ELFRLRVLELNASDERG 115
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPgyddpnEDFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 116 IQVVREKVKNfaqltVSGSRSDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCS 195
Cdd:PRK14970 90 VDDIRNLIDQ-----VRIPPQTGK----YKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4506491 196 KFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTgGKEITEKVITDIAGVI 269
Cdd:PRK14970 161 IFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFC-GKNITRQAVTENLNIL 233
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
42-335 |
5.77e-20 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 91.06 E-value: 5.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 42 EKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTS--TILAAARELFGP------------ELFR---- 102
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSiaKIFAKAINCLNPkdgdccnscsvcESINtnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 LRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNY 182
Cdd:PRK05896 88 VDIVELDAASNNGVDEIRNIIDNINYLPTTFK---------YKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 183 VSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTgGKEITEK 260
Cdd:PRK05896 159 FQKI--PLTiiSRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFK-NSEIDIE 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4506491 261 VITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVD 335
Cdd:PRK05896 236 DINKTFGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQKTKNINLLKKLSKE 310
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
43-255 |
7.09e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 90.78 E-value: 7.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELFGP-------------ELFR---L 103
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHaYIFFGPRGVGKTTIarILAKRLNCENPignepcnectsclEITKgisS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVREKVKNfaqltVSGSRSDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK14956 91 DVLEIDAASNRGIENIRELRDN-----VKFAPMGGK----YKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEF 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGK 255
Cdd:PRK14956 162 HKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSK 233
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
45-267 |
8.67e-20 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 90.12 E-value: 8.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 45 RPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTS--TILAAArelfgpelFRLRVLELNASDErGIQVV 119
Cdd:COG2256 20 RPRTLDEVVGQEHLLGpgkPLRRAIEAGRLSSMILWGPPGTGKTTlaRLIANA--------TDAEFVALSAVTS-GVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 120 REKVKNfAQLtvsgSRSDGKPCppfkIVILDEADSMTSAAQAALRRTMEKESKTtrfcLIC----N-YVSrIIEPLTSRC 194
Cdd:COG2256 91 REVIEE-ARE----RRAYGRRT----ILFVDEIHRFNKAQQDALLPHVEDGTIT----LIGatteNpSFE-VNSALLSRC 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 195 SKFRFKPLSDK-IQQ--QRLLDIAKK----ENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLT---GGKEITEKVITD 264
Cdd:COG2256 157 RVFVLKPLSEEdLEQllERALADDERglggYKLELDDEALEALARLADGDARRALNALELAVLSAppdGVIEITLELVEE 236
|
...
gi 4506491 265 IAG 267
Cdd:COG2256 237 ALQ 239
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
43-307 |
2.66e-19 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 89.06 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAAREL---FGP------ELF---------RL 103
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANaYIFSGPRGVGKTSSARAFARCLncvNGPtpmpcgECSscksidndnSL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVREkVKNFAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK06647 89 DVIEIDGASNTSVQDVRQ-IKEEIMFPPASSR--------YRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGkEITEKVIT 263
Cdd:PRK06647 160 HKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDS-DITLEQIR 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 4506491 264 DIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLV 307
Cdd:PRK06647 239 SKMGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFL 282
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
43-315 |
3.46e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 85.21 E-value: 3.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELFGPELFR------------------- 102
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHaYLFSGIRGTGKTTLARIFAKALNCQNPTEdqepcnqcasckeissgts 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 LRVLELNASDERGIQVVREkvknfAQLTVSGSRSDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNY 182
Cdd:PRK06305 90 LDVLEIDGASHRGIEDIRQ-----INETVLFTPSKSR----YKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 183 VSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITEKVI 262
Cdd:PRK06305 161 IHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKS-LDPDSV 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 4506491 263 TDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLvnqLHDVVV 315
Cdd:PRK06305 240 AKALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHF---LHDLTL 289
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
74-202 |
1.37e-17 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 78.02 E-value: 1.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARELfgpelfRLRVLELNASDERGIQvVREKVKNFAQLtVSGSRSDgKPCppfkIVILDEAD 153
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKEL------GAPFIEISGSELVSKY-VGESEKRLREL-FEAAKKL-APC----VIFIDEID 67
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4506491 154 SMTSA-----------AQAALRRTMEKESKTTR---FCLICNYVSRIIEPLTSRCSKFRFKPL 202
Cdd:pfam00004 68 ALAGSrgsggdsesrrVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
43-315 |
1.80e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 83.64 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA------------------RELfgPELF 101
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTarILAKAlnceqgltaepcnvcppcVEI--TEGR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 102 RLRVLELNASDERGIQVVREKVKNFAQLTvSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICN 181
Cdd:PRK14965 87 SVDVFEIDGASNTGVDDIRELRENVKYLP-SRSR--------YKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 182 YVSRIIEPLTSRCSKFRFK--PLSdKIqQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSaTRLTGGKEITE 259
Cdd:PRK14965 158 EPHKVPITILSRCQRFDFRriPLQ-KI-VDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQ-VLAFCGDAVGD 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 260 KVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQ----LVNQLHDVVV 315
Cdd:PRK14965 235 DDVAELLGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQfcqeLIDHLRNLVV 294
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
43-310 |
2.00e-17 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 83.38 E-value: 2.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEG-----AdlpnLLFYGPPGTGKTST--ILAAARELFGP---------ELFR---- 102
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQgkishA----YLFSGPRGTGKTSAakIFAKAVNCLNPpdgepcnecEICKaitn 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 ---LRVLELNASDERG---IQVVREKVKnFAQltvsgsrSDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRF 176
Cdd:PRK05563 85 gslMDVIEIDAASNNGvdeIRDIRDKVK-YAP-------SEAK----YKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 177 CLICNYVSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGG 254
Cdd:PRK05563 153 ILATTEPHKI--PATilSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDG 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 255 KeITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQL 310
Cdd:PRK05563 231 K-VTYEDALEVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDL 285
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
30-276 |
3.22e-17 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 83.18 E-value: 3.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 30 GENKKAKPVPWVEKYRPKCVDEVAFQEEVVA---VLKKSLEGADLPNLLFYGPPGTGKTS--TILAAArelfgpelFRLR 104
Cdd:PRK13341 8 GEQMSQSEAPLADRLRPRTLEEFVGQDHILGegrLLRRAIKADRVGSLILYGPPGVGKTTlaRIIANH--------TRAH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 105 VLELNASdERGIQVVREKVKN-FAQLTVSGSRSdgkpcppfkIVILDEADSMTSAAQAALRRTMEKESKTtrfcLIC--- 180
Cdd:PRK13341 80 FSSLNAV-LAGVKDLRAEVDRaKERLERHGKRT---------ILFIDEVHRFNKAQQDALLPWVENGTIT----LIGatt 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 181 -NYVSRIIEPLTSRCSKFRFKPLSD----KIQQQRLLDIAK---KENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLT 252
Cdd:PRK13341 146 eNPYFEVNKALVSRSRLFRLKSLSDedlhQLLKRALQDKERgygDRKVDLEPEAEKHLVDVANGDARSLLNALELAVEST 225
|
250 260
....*....|....*....|....
gi 4506491 253 GGKEITekvITDIAGVIPAEKIDG 276
Cdd:PRK13341 226 PPDEDG---LIDITLAIAEESIQQ 246
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
43-269 |
7.46e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 81.37 E-value: 7.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAAREL---FGP---------ELFRLR----- 104
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCARIISLCLncsNGPtsdpcgtchNCISIKnsnhp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 105 -VLELNASDERGIQVVREKVKNFAQLTVSgSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK14964 86 dVIEIDAASNTSVDDIKVILENSCYLPIS-SK--------FKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 SRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITEKV 261
Cdd:PRK14964 157 KKI--PVTiiSRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNK-ISEKS 233
|
....*...
gi 4506491 262 ITDIAGVI 269
Cdd:PRK14964 234 VRDLLGCV 241
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
202-266 |
8.81e-17 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 73.72 E-value: 8.81e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4506491 202 LSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRltGGKEITEKVITDIA 266
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAA--GGGVITEEDVYEVA 63
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
43-270 |
1.25e-16 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 81.16 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADL-PNLLFYGPPGTGKTST--ILAaaRELF-----GP--------ELFR---- 102
Cdd:PRK14948 9 KYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSarILA--KSLNclnsdKPtpepcgkcELCRaiaa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 ---LRVLELNASDERGIQVVREKVKNfAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLI 179
Cdd:PRK14948 87 gnaLDVIEIDAASNTGVDNIRELIER-AQFAPVQAR--------WKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 180 CNYVSRIIEPLTSRCSKFRFK--PLSDKIQQqrLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGkeI 257
Cdd:PRK14948 158 TTDPQRVLPTIISRCQRFDFRriPLEAMVQH--LSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLLPGP--I 233
|
250
....*....|...
gi 4506491 258 TEKVITDIAGVIP 270
Cdd:PRK14948 234 TPEAVWDLLGAVP 246
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
39-300 |
2.44e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 80.11 E-value: 2.44e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSL-EGADLPNLLFYGPPGTGKTSTILAAAREL---FGP--------ELFR---- 102
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAqENRVAPAYLFSGTRGVGKTTIARIFAKALnceTAPtgepcntcEQCRkvtq 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 ---LRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLI 179
Cdd:PRK14959 85 gmhVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGR---------YKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 180 CNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLtGGKEITE 259
Cdd:PRK14959 156 TTEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLAL-GESRLTI 234
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 4506491 260 KVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEG 300
Cdd:PRK14959 235 DGARGVLGLAGQELFLRLMEALAAQDCLGVANVVRELLDRG 275
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
43-296 |
1.69e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 77.38 E-value: 1.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELF---GP---------------ELFRL 103
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHaYLFSGLRGSGKTSSARIFARALVceqGPsstpcdtciqcqsalENRHI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVREKVKNfAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNyv 183
Cdd:PRK08451 87 DIIEMDAASNRGIDDIRELIEQ-TKYKPSMAR--------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATT-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 sriiEPLT------SRCSKFRFKplsdKIQQQRLLD----IAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATrLTG 253
Cdd:PRK08451 156 ----DPLKlpatilSRTQHFRFK----QIPQNSIIShlktILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAI-IYC 226
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 4506491 254 GKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDL 296
Cdd:PRK08451 227 KNAITESKVADMLGLLDPSKLEDFFQAILNQDKEKLFELLKEL 269
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
43-321 |
1.82e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 77.54 E-value: 1.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSL-EGADLPNLLFYGPPGTGKTST--ILAAARELFGPELfRLR--------------- 104
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIaEGRVAHAYLFTGPRGVGKTSTarILAKAVNCTTNDP-KGRpcgtcemcraiaegs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 105 ---VLELNASDERGIQVVREkVKNFAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICN 181
Cdd:PRK14950 88 avdVIEMDAASHTSVDDARE-IIERVQFRPALAR--------YKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 182 YVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFL-QSATrlTGGKEITEK 260
Cdd:PRK14950 159 EVHKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLqQLAT--TYGGEISLS 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4506491 261 VITDIAGVIPAEKI----DGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSD 321
Cdd:PRK14950 237 QVQSLLGISGDEEVkalaEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSGAD 301
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
43-274 |
2.78e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 76.00 E-value: 2.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLE-GADLPNLLFYGPPGTGKTSTILAAAREL-----FGPELFR-------------L 103
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSlGRIHHAWLLSGTRGVGKTTIARLLAKSLncqngITSNPCRkciickeiekglcL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 104 RVLELNASDERGIQVVREKVKNFaQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYV 183
Cdd:PRK14961 89 DLIEIDAASRTKVEEMREILDNI-YYSPSKSR--------FKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 184 SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGkEITEKVIT 263
Cdd:PRK14961 160 EKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKG-NINIKNVT 238
|
250
....*....|.
gi 4506491 264 DIAGVIPAEKI 274
Cdd:PRK14961 239 DMLGLLNEKQS 249
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
43-338 |
6.76e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 75.54 E-value: 6.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILAAA------------------RELFG---P 98
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHaYLFTGTRGVGKTtiSRILAKClncekgvsanpcndcencREIDEgrfP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 99 ELFrlrvlELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCL 178
Cdd:PRK14958 89 DLF-----EVDAASRTKVEDTRELLDNIPYAPTKGR---------FKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFIL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 179 ICNYVSRIIEPLTSRCSKF---RFKPLSDKIQQQRLLdiaKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGK 255
Cdd:PRK14958 155 ATTDHHKLPVTVLSRCLQFhlaQLPPLQIAAHCQHLL---KEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 256 EITEKVITDIAGVIPAEKIDgVFAACQSGSFDKLEAVVKDLIDEG----HAATQLVNQLHDVVVENNLSDKQKSIITEKL 331
Cdd:PRK14958 232 VLIADVKTMLGTIEPLLLFD-ILEALAAKAGDRLLGCVTRLVEQGvdfsNALADLLSLLHQIAIIQTVPEALIENDSEQL 310
|
....*..
gi 4506491 332 AEVDKCL 338
Cdd:PRK14958 311 RQLAKLL 317
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
43-296 |
7.49e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 75.50 E-value: 7.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAAREL-------------------FGPELFr 102
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHaYLFTGTRGVGKTTLGRLLAKCLncktgvtaepcnkcencvaINNNSF- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 LRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNY 182
Cdd:PRK14957 88 IDLIEIDAASRTGVEETKEILDNIQYMPSQGR---------YKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 183 VSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGkEITEKVI 262
Cdd:PRK14957 159 YHKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGG-ELKQAQI 237
|
250 260 270
....*....|....*....|....*....|....
gi 4506491 263 TDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDL 296
Cdd:PRK14957 238 KQMLGIIDSEEVYSIINAIIDNDPKAILPAIKNL 271
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
50-247 |
4.53e-14 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 71.86 E-value: 4.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 50 DEVAFQEEVVAVLKKSLEGADL-PNLLFYGPPGTGKTSTILAAARELF----GPELFRLRVLELNASD------------ 112
Cdd:PRK07399 4 ANLIGQPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLsqgsPSKNIRRRLEEGNHPDllwveptyqhqg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 113 ---------ERGI------QV----VREkVKNF-AQLTVSGSRsdgkpcppfKIVILDEADSMTSAAQAALRRTMEkESK 172
Cdd:PRK07399 84 klitaseaeEAGLkrkappQIrleqIRE-IKRFlSRPPLEAPR---------KVVVIEDAETMNEAAANALLKTLE-EPG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4506491 173 TTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS 247
Cdd:PRK07399 153 NGTLILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAAIANIEQLQS 227
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
31-274 |
1.94e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 71.04 E-value: 1.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 31 ENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKS-LEGADLPNLLFYGPPGTGKTST--ILAAARELFGP--ELFRLR- 104
Cdd:PRK06645 2 INSSNQYIPFARKYRPSNFAELQGQEVLVKVLSYTiLNDRLAGGYLLTGIRGVGKTTSarIIAKAVNCSALitENTTIKt 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 105 -----------------VLELNASDERGIQVVREKVKNfaqltvsgsrSDGKPCP-PFKIVILDEADSMTSAAQAALRRT 166
Cdd:PRK06645 82 ceqctncisfnnhnhpdIIEIDAASKTSVDDIRRIIES----------AEYKPLQgKHKIFIIDEVHMLSKGAFNALLKT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 167 MEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQ 246
Cdd:PRK06645 152 LEEPPPHIIFIFATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILD 231
|
250 260 270
....*....|....*....|....*....|
gi 4506491 247 SATRLTG--GKEITEKVITDIAGVIPAEKI 274
Cdd:PRK06645 232 QAASMSAksDNIISPQVINQMLGLVDSSVI 261
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
43-264 |
1.44e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 68.65 E-value: 1.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAARELFGP-----------------ELFR 102
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTCarIFAKTINCQNLtadgeacnecescvafnEQRS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 LRVLELNASDERGIQVVR---EKVKNFAQLtvsgsrsdGKpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLI 179
Cdd:PRK14971 90 YNIHELDAASNNSVDDIRnliEQVRIPPQI--------GK----YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 180 CNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITE 259
Cdd:PRK14971 158 TTEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGN-ITY 236
|
....*
gi 4506491 260 KVITD 264
Cdd:PRK14971 237 KSVIE 241
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
55-203 |
3.05e-12 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 64.15 E-value: 3.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 55 QEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELFGPELFR----------LRVLELN-------ASDERGI 116
Cdd:pfam13177 2 QPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDdlpcgqcrscRRIESGNhpdlviiEPEGQSI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 117 QV--VREKVKNFAQLTVSGSRsdgkpcppfKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 194
Cdd:pfam13177 82 KIdqIRELQKEFSKSPYEGKK---------KVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRC 152
|
....*....
gi 4506491 195 SKFRFKPLS 203
Cdd:pfam13177 153 QIIRFKPLS 161
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
43-255 |
1.01e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 66.27 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILA------------------AARELFGPELF 101
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIarILAkslncenaqhgepcgvcqSCTQIDAGRYV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 102 RLrvLELNASDERGIQVVREKVKNfAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICN 181
Cdd:PRK08691 89 DL--LEIDAASNTGIDNIREVLEN-AQYAPTAGK--------YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATT 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4506491 182 YVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGK 255
Cdd:PRK08691 158 DPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGK 231
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
39-139 |
1.01e-11 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 66.40 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTilAAARELFGPELFRLRVLELNASDER-GIQ 117
Cdd:PRK04132 8 PWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLT--GDTKVIANGELFEIGELVEKISNGKfGPT 85
|
90 100
....*....|....*....|..
gi 4506491 118 VVRekvknfaQLTVSGSRSDGK 139
Cdd:PRK04132 86 PVN-------GLKVLGIDEDGK 100
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
43-269 |
1.17e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 65.92 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILA------------------AARELFGPELF 101
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHaYLFTGTRGVGKTtlARILAkslncetgvtatpcgvcsACLEIDSGRFV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 102 RLrvLELNASDERGIQVVREKVKNfAQLTVSGSRsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICN 181
Cdd:PRK14969 89 DL--IEVDAASNTQVDAMRELLDN-AQYAPTRGR--------FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 182 YVSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLtGGKEITE 259
Cdd:PRK14969 158 DPQKI--PVTvlSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAY-GGGTVNE 234
|
250
....*....|
gi 4506491 260 KVITDIAGVI 269
Cdd:PRK14969 235 SEVRAMLGAI 244
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
56-328 |
1.22e-10 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 61.98 E-value: 1.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLEGADLPN-LLFYGPPGTGKTS-------TIL-----AAARELFG-PE----LFRL-------RVLELNA 110
Cdd:PRK09112 29 EEAEAFLAQAYREGKLHHaLLFEGPEGIGKATlafhlanHILshpdpAEAPETLAdPDpaspVWRQiaqgahpNLLHITR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 111 S-DER------GIQV--VREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICN 181
Cdd:PRK09112 109 PfDEKtgkfktAITVdeIRRVGHFLSQTSGDGN---------WRIVIIDPADDMNRNAANAILKTLEEPPARALFILISH 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 182 YVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENvkISDEGIAYLVKVSEGDLRKAITFLQSatrltGGKEITEKV 261
Cdd:PRK09112 180 SSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQG--SDGEITEALLQRSKGSVRKALLLLNY-----GGLEIIATI 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 262 ITDIAGVIP--------AEKIDGVFAACQSGSF-----DKLEAVVKDLIDEGHAAT-----QLVNQLHDVVVEN---NLs 320
Cdd:PRK09112 253 DQLLAGSGPdarkahklADALSGRESEVQFDFFrdhllDRIMAEARRAAEAGDLALaerlaRLWSEIIEEIVEAeayNL- 331
|
....*...
gi 4506491 321 DKQKSIIT 328
Cdd:PRK09112 332 DRKQTVIS 339
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
43-320 |
2.31e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 61.45 E-value: 2.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA----RELFGPELFR------------- 102
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAarVFAKAvncqRMIDDADYLQevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 -------LRVLELNASDERG---IQVVREKVKNFAQltvsgsrsDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESK 172
Cdd:PRK14955 89 dfdagtsLNISEFDAASNNSvddIRLLRENVRYGPQ--------KGR----YRVYIIDEVHMLSIAAFNAFLKTLEEPPP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 173 TTRFCLICNYVSRIIEPLTSRCSKFRFK--PLSDkIQQQrLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS--- 247
Cdd:PRK14955 157 HAIFIFATTELHKIPATIASRCQRFNFKriPLEE-IQQQ-LQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQvia 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 248 -ATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGS----FDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLS 320
Cdd:PRK14955 235 fSVESEGEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDavamLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHNLR 312
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
43-348 |
3.37e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 61.60 E-value: 3.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILA-----------------AARELFGPELFr 102
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHaYLFTGTRGVGKTTIarILAkclncetgvtstpcevcATCKAVNEGRF- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 LRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNY 182
Cdd:PRK14960 87 IDLIEIDAASRTKVEDTRELLDNVPYAPTQGR---------FKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 183 VSRIIEPLTSRCSKFRFKPLS-DKIQQQrLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITEKV 261
Cdd:PRK14960 158 PQKLPITVISRCLQFTLRPLAvDEITKH-LGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGA-VHHQD 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 262 ITDIAGVIPAEKI-DGVFAACQsgsfDKLEAVVKDLIDEGHAA-------TQLVNQLHDVVVENNLSD---KQKSIITEK 330
Cdd:PRK14960 236 VKEMLGLIDRTIIyDLILAVHQ----NQREKVSQLLLQFRYQAldvslvlDQLISTLHELALLQYLPElglKYSEEINAK 311
|
330
....*....|....*...
gi 4506491 331 LAEVDKCLadgADEHLQL 348
Cdd:PRK14960 312 ILQLSKLI---SAQDLQL 326
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
73-199 |
4.11e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 57.77 E-value: 4.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 73 NLLFYGPPGTGKTSTILAAARELFGPElfrLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDG---------KPCPp 143
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPG---GGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRlrlalalarKLKP- 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4506491 144 fKIVILDEADSMTSAAQAALRR--------TMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRF 199
Cdd:smart00382 80 -DVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
56-259 |
2.99e-09 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 57.94 E-value: 2.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL---FGPELFRLRVLELNASDERGI-QVVR---EKVKNFAQ 128
Cdd:COG1474 36 EELASALRPALRGERPSNVLIYGPTGTGKTAVAKYVLEELeeeAEERGVDVRVVYVNCRQASTRyRVLSrilEELGSGED 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 129 LTVSG-SRSD------------GKPCppfkIVILDEADSMTSAAQ----AALRRTMEkESKTTRFCLICnyVSR---IIE 188
Cdd:COG1474 116 IPSTGlSTDElfdrlyealderDGVL----VVVLDEIDYLVDDEGddllYQLLRANE-ELEGARVGVIG--ISNdleFLE 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 189 PLTSR------CSKFRFKP-----LSDkIQQQRlLDIAKKENVkISDEGIAYLVKVS---EGDLRKAITFLQSATRL--- 251
Cdd:COG1474 189 NLDPRvksslgEEEIVFPPydadeLRD-ILEDR-AELAFYDGV-LSDEVIPLIAALAaqeHGDARKAIDLLRVAGEIaer 265
|
....*...
gi 4506491 252 TGGKEITE 259
Cdd:COG1474 266 EGSDRVTE 273
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
50-263 |
7.59e-09 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 55.66 E-value: 7.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 50 DEVAFQEEVVAVLK---KSLEGADLP---------NLLFYGPPGTGKTSTILAAARELfgpelfRLRVLELNASDERGiQ 117
Cdd:COG1223 2 DDVVGQEEAKKKLKliiKELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLDSLIG-S 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 118 VVREKVKNFAQLTvsgSRSDGKPCppfkIVILDEADSMtsaaqaALRRTMEKESKTTR----------------FCLIC- 180
Cdd:COG1223 75 YLGETARNLRKLF---DFARRAPC----VIFFDEFDAI------AKDRGDQNDVGEVKrvvnallqeldglpsgSVVIAa 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 181 -NYVSRIIEPLTSRCS-KFRFkPLSDKIQQQRLLD--IAK-KENVKISDEGIAYLVK-VSEGDLRKAITFLQSATRLTGG 254
Cdd:COG1223 142 tNHPELLDSALWRRFDeVIEF-PLPDKEERKEILElnLKKfPLPFELDLKKLAKKLEgLSGADIEKVLKTALKKAILEDR 220
|
....*....
gi 4506491 255 KEITEKVIT 263
Cdd:COG1223 221 EKVTKEDLE 229
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
39-276 |
9.87e-09 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 56.89 E-value: 9.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-----LLFYGPPGTGKTSTILAAAREL-------FGPELFRLRVL 106
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKELgiqvqewSNPTLPDFQKN 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 107 ELNASDERG--IQVVREKVKNFAQLTVSGSRSDGKPCPPF----KIVILDEADSMTSAAQAALRRTME-KESKTTRFCLI 179
Cdd:TIGR00602 153 DHKVTLSLEscFSNFQSQIEVFSEFLLRATNKLQMLGDDLmtdkKIILVEDLPNQFYRDTRALHEILRwKYVSIGRCPLV 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 180 CnYVSRIIEPLTS--------------------RCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAY-------LVK 232
Cdd:TIGR00602 233 F-IITESLEGDNNqrrllfpaetimnkeileepRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPkktsvelLCQ 311
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 4506491 233 VSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDG 276
Cdd:TIGR00602 312 GCSGDIRSAINSLQFSSSKSGSLPIKKRMSTKSDAHASKSKIKG 355
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
43-262 |
1.75e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 56.10 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTST--ILAAA----RELFGPELFR------------- 102
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAarVFAKAvncqRMIDDPVYLQevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 103 -------LRVLELNASDERG---IQVVREKVKNFAQltvsgsrsDGKpcppFKIVILDEADSMTSAAQAALRRTMEKESK 172
Cdd:PRK14954 89 dfdagtsLNISEFDAASNNSvddIRQLRENVRYGPQ--------KGR----YRVYIIDEVHMLSTAAFNAFLKTLEEPPP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 173 TTRFCLICNYVSRIIEPLTSRCSKFRFK--PLsDKIQQQrLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATR 250
Cdd:PRK14954 157 HAIFIFATTELHKIPATIASRCQRFNFKriPL-DEIQSQ-LQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIA 234
|
250
....*....|..
gi 4506491 251 LTGGKEiTEKVI 262
Cdd:PRK14954 235 FSVGSE-AEKVI 245
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
145-310 |
4.24e-08 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 54.10 E-value: 4.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 145 KIVILDEADSMT--SAAQAALRRTMEKESKTTRFCLICNYV---SRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKEN 219
Cdd:COG1466 64 RLVIVRNAEFLKkpGEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 220 VKISDEGIAYLVKVSEGDLRKAITFLQS-ATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLID 298
Cdd:COG1466 144 LRIDPDAAQLLAERVGGDLLALAQELEKlALYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLA 223
|
170
....*....|..
gi 4506491 299 EGHAATQLVNQL 310
Cdd:COG1466 224 EGEEPVLILAAL 235
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
210-262 |
4.32e-08 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 49.39 E-value: 4.32e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 4506491 210 RLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVI 262
Cdd:cd18133 9 RLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRV 61
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
43-255 |
1.76e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 52.79 E-value: 1.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILAAARELFGPE-------------------- 99
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHaYLFTGTRGVGKTtvSRILAKSLNCQGPDgqggitatpcgvcqacrdid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 100 --LFrLRVLELNASDERGIQVVREKVKNFAQLTVSGSrsdgkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFC 177
Cdd:PRK14951 89 sgRF-VDYTELDAASNRGVDEVQQLLEQAVYKPVQGR---------FKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 178 LICNYVSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGK 255
Cdd:PRK14951 159 LATTDPQKV--PVTvlSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQ 236
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
39-100 |
2.48e-07 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 50.34 E-value: 2.48e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4506491 39 PWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-----LLFYGPPGTGKTSTILAAARELfGPEL 100
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL-GPKY 73
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
72-175 |
5.07e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.82 E-value: 5.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 72 PNLLFYGPPGTGKTSTILAAARELfGPELFRLRVLELNasdERGIQVVREKVKN-FAQLtvsgsrSDGKPCppfkIVILD 150
Cdd:cd19481 27 KGILLYGPPGTGKTLLAKALAGEL-GLPLIVVKLSSLL---SKYVGESEKNLRKiFERA------RRLAPC----ILFID 92
|
90 100
....*....|....*....|....*
gi 4506491 151 EADSMtsaaqaALRRTMEKESKTTR 175
Cdd:cd19481 93 EIDAI------GRKRDSSGESGELR 111
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
75-262 |
5.53e-07 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 50.34 E-value: 5.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 75 LFYGPPGTGKTSTILAAARE-----------LFGP-ELFRLRVLELNASDERG-----IQVVREKVKNFAQLtvsgsrsd 137
Cdd:COG2842 54 VVYGESGVGKTTAAREYANRnpnviyvtaspSWTSkELLEELAEELGIPAPPGtiadlRDRILERLAGTGRL-------- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 138 gkpcppfkiVILDEADSMTSAAQAALRR------------TMEK-ESKTTRFCLIcnyVSRIIEpltsrcsKFRFKPLSD 204
Cdd:COG2842 126 ---------LIIDEADHLKPKALEELRDihdetgvgvvliGMERlPAKLKRYEQL---YSRIGF-------WVEFKPLSL 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4506491 205 KiQQQRLLDIAkkENVKISDEgIAYLVKVSEGDLR---KAITFLQSATRLTGGKEITEKVI 262
Cdd:COG2842 187 E-DVRALAEAW--GELTDPDL-LELLHRITRGNLRrldRTLRLAARAAKRNGLTKITLDHV 243
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
145-236 |
5.88e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 50.42 E-value: 5.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 145 KIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSdkiQQQRLLDIAKKENVkISD 224
Cdd:PRK05564 95 KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLS---KEEIEKFISYKYND-IKE 170
|
90
....*....|..
gi 4506491 225 EGIAYLVKVSEG 236
Cdd:PRK05564 171 EEKKSAIAFSDG 182
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
45-95 |
1.12e-06 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 47.88 E-value: 1.12e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 45 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKTSTILAAAREL 95
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHVLLYGPPGLGKTTLANIIANEM 57
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
102-245 |
1.23e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 49.64 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 102 RLRVLELNASDERG-----IQV--VREkVKNFAQLT--VSGSRsdgkpcppfkIVILDEADSMTSAAQAALRRTMEKESK 172
Cdd:PRK07471 102 GLLTLERSWNEKGKrlrtvITVdeVRE-LISFFGLTaaEGGWR----------VVIVDTADEMNANAANALLKVLEEPPA 170
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4506491 173 TTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAkkenVKISDEGIAYLVKVSEGDLRKAITFL 245
Cdd:PRK07471 171 RSLFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDALAAAG----PDLPDDPRAALAALAEGSVGRALRLA 239
|
|
| PRK08058 |
PRK08058 |
DNA polymerase III subunit delta'; Validated |
55-213 |
1.38e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181214 [Multi-domain] Cd Length: 329 Bit Score: 49.54 E-value: 1.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 55 QEEVVAVLKKSLEGADLPN-LLFYGPPGTGKTSTILAAARELFGPELFR----------LRVLELN-------ASDERGI 116
Cdd:PRK08058 11 QPVVVKMLQNSIAKNRLSHaYLFEGAKGTGKKATALWLAKSLFCLERNGvepcgtctncKRIDSGNhpdvhlvAPDGQSI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 117 QV--VREKVKNFAQLTVSGSRsdgkpcppfKIVILDEADSMT-SAAQAALRRTMEKESKTTRFCLICNYvSRIIEPLTSR 193
Cdd:PRK08058 91 KKdqIRYLKEEFSKSGVESNK---------KVYIIEHADKMTaSAANSLLKFLEEPSGGTTAILLTENK-HQILPTILSR 160
|
170 180
....*....|....*....|
gi 4506491 194 CSKFRFKPLSDKIQQQRLLD 213
Cdd:PRK08058 161 CQVVEFRPLPPESLIQRLQE 180
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
56-242 |
3.44e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 48.37 E-value: 3.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLE-----GADLPN-LLFYGPPGTGKTSTILAAARELFGPelfrlrVLELNASDERGiQVVREKVKNFAQL 129
Cdd:COG0464 170 RELVALPLKRPElreeyGLPPPRgLLLYGPPGTGKTLLARALAGELGLP------LIEVDLSDLVS-KYVGETEKNLREV 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 130 --TVSGSrsdgKPCppfkIVILDEADSMTSAAQAALRRTMEK---------ESKTTRFCLIC--NYVSRIIEPLTSRC-S 195
Cdd:COG0464 243 fdKARGL----APC----VLFIDEADALAGKRGEVGDGVGRRvvntlltemEELRSDVVVIAatNRPDLLDPALLRRFdE 314
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 4506491 196 KFRFkPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEG----DLRKAI 242
Cdd:COG0464 315 IIFF-PLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEGlsgaDIRNVV 364
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
45-95 |
7.22e-06 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 47.43 E-value: 7.22e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 45 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKTStiLAA--AREL 95
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTT--LANiiANEM 75
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
205-267 |
8.42e-06 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 43.39 E-value: 8.42e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 205 KIQQQRLLDIAK--KENVKISDEGIAYLVKVSEGDLRKAITFLQ---SATRLTGGKEITEKVITDIAG 267
Cdd:cd18139 8 KLLKRALEDKERggDRKVTIDDEALELLAEAADGDARSALNLLElavLSAEEDGGIVITLEDLEEVLQ 75
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
43-267 |
1.68e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.77 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 43 KYRPKCVDEVAFQEEVVAVLKKSLEGADLPN-LLFYGPPGTGKT--STILA------------------AARELfgPELF 101
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTtlSRIFAkalncetgvtsqpcgvcrACREI--DEGR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 102 RLRVLELNASDERGiqvvrekVKNFAQLTvsgSRSDGKPCPP-FKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLIC 180
Cdd:PRK07003 87 FVDYVEMDAASNRG-------VDEMAALL---ERAVYAPVDArFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 181 NYVSRIiePLT--SRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTgGKEIT 258
Cdd:PRK07003 157 TDPQKI--PVTvlSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYS-ANEVT 233
|
....*....
gi 4506491 259 EKVITDIAG 267
Cdd:PRK07003 234 ETAVSGMLG 242
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
53-158 |
2.02e-05 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 44.20 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 53 AFQEEVVAVLKKSLE----GADLPN-LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVR 120
Cdd:cd19511 4 ELKEAVEWPLKHPDAfkrlGIRPPKgVLLYGPPGCGKTLLAKALASEaglnfisVKGPELFSKYVGE----SERAVREIF 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 4506491 121 EKVKnfaqltvsgsrsDGKPCppfkIVILDEADSMTSA 158
Cdd:cd19511 80 QKAR------------QAAPC----IIFFDEIDSLAPR 101
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
56-151 |
2.79e-05 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 45.92 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSlegadlPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNAS--DERGIQ-----------VVREK 122
Cdd:COG1401 212 EAFLAALKTK------KNVILAGPPGTGKTYLARRLAEALGGEDNGRIEFVQFHPSwsYEDFLLgyrpsldegkyEPTPG 285
|
90 100
....*....|....*....|....*....
gi 4506491 123 VknFAQLTVSGSRSDGKPCppfkIVILDE 151
Cdd:COG1401 286 I--FLRFCLKAEKNPDKPY----VLIIDE 308
|
|
| cdc6 |
PRK00411 |
ORC1-type DNA replication protein; |
56-248 |
4.21e-05 |
|
ORC1-type DNA replication protein;
Pssm-ID: 234751 [Multi-domain] Cd Length: 394 Bit Score: 45.22 E-value: 4.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELfGPELFRLRVLELNasdergIQVVREKVKNFAQLtvsGSR 135
Cdd:PRK00411 40 EELAFALRPALRGSRPLNVLIYGPPGTGKTTTVKKVFEEL-EEIAVKVVYVYIN------CQIDRTRYAIFSEI---ARQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 136 SDGKPCP----PFK-----------------IVILDEADSM--TSAAQA--ALRRTMEkESKTTRFCLICnyVSR---II 187
Cdd:PRK00411 110 LFGHPPPssglSFDelfdkiaeylderdrvlIVALDDINYLfeKEGNDVlySLLRAHE-EYPGARIGVIG--ISSdltFL 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4506491 188 EPLTSRC-SKFR-----FKP-----LSDkIQQQRlLDIAKKENVkISDEG---IAYLVKVSEGDLRKAITFLQSA 248
Cdd:PRK00411 187 YILDPRVkSVFRpeeiyFPPytadeIFD-ILKDR-VEEGFYPGV-VDDEVldlIADLTAREHGDARVAIDLLRRA 258
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
56-248 |
4.80e-05 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 44.93 E-value: 4.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL---FGPELFRLRVLELNASDERGI-QVVREKVKNFAQLTV 131
Cdd:TIGR02928 25 EELAKALRPILRGSRPSNVFIYGKTGTGKTAVTKYVMKELeeaAEDRDVRVVTVYVNCQILDTLyQVLVELANQLRGSGE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 132 S-------------------GSRSDgkpcppFKIVILDEADSMTSAAQAAL------RRTMEKESKTTRFCLICNYVSrI 186
Cdd:TIGR02928 105 EvpttglstsevfrrlykelNERGD------SLIIVLDEIDYLVGDDDDLLyqlsraRSNGDLDNAKVGVIGISNDLK-F 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 4506491 187 IEPLTSRC-SKFR-----FKP-----LSDkIQQQRlLDIAKKENVkISDEGI---AYLVKVSEGDLRKAITFLQSA 248
Cdd:TIGR02928 178 RENLDPRVkSSLCeeeiiFPPydaeeLRD-ILENR-AEKAFYDGV-LDDGVIplcAALAAQEHGDARKAIDLLRVA 250
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
45-95 |
5.38e-05 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 44.69 E-value: 5.38e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 45 RPKCVDEVAFQEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKT--STILaaAREL 95
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEAAKkrgeaLDHVLLYGPPGLGKTtlAHII--ANEM 78
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
78-162 |
6.07e-05 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 43.32 E-value: 6.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 78 GPPGTGKTsTILAAARELFGPELFRLRVLelnASDERGIQVVRE----KVKNFAQLTvsGSRSDGKPCPPFKIVILDEAd 153
Cdd:pfam13604 25 GPAGTGKT-TALKALREAWEAAGYRVIGL---APTGRAAKVLGEelgiPADTIAKLL--HRLGGRAGLDPGTLLIVDEA- 97
|
....*....
gi 4506491 154 SMTSAAQAA 162
Cdd:pfam13604 98 GMVGTRQMA 106
|
|
| PRK05917 |
PRK05917 |
DNA polymerase III subunit delta'; Validated |
143-264 |
7.30e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 102059 [Multi-domain] Cd Length: 290 Bit Score: 44.02 E-value: 7.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 143 PFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRfkplsdkiqqqrlldIAKKENVKI 222
Cdd:PRK05917 95 PYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIH---------------IPMEEKTLV 159
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 4506491 223 SDEGIAYLVKVSEGDlrkaITFLQSATRLTGGKEITEKVITD 264
Cdd:PRK05917 160 SKEDIAYLIGYAQGK----ESVTEVGQIVKGSADTDKQVLRD 197
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
9-95 |
9.41e-05 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 43.84 E-value: 9.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 9 SISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCV-DEVAFQEEVVAVLKKSLE------------GADLPN-L 74
Cdd:COG1222 36 VKALELLEEAPALLLNDANLTQKRLGTPRGTAVPAESPDVTfDDIGGLDEQIEEIREAVElplknpelfrkyGIEPPKgV 115
|
90 100
....*....|....*....|.
gi 4506491 75 LFYGPPGTGKTSTILAAAREL 95
Cdd:COG1222 116 LLYGPPGTGKTLLAKAVAGEL 136
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
74-211 |
1.81e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 42.77 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTS-------TILAAARELFG----------------PELFRLRVLElnASDERGIQVVREKVkNFAQLT 130
Cdd:PRK05707 25 YLLHGPAGIGKRAlaerlaaALLCEAPQGGGacgsckgcqllragshPDNFVLEPEE--ADKTIKVDQVRELV-SFVVQT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 131 vsgSRSDGkpcppFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQR 210
Cdd:PRK05707 102 ---AQLGG-----RKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQW 173
|
.
gi 4506491 211 L 211
Cdd:PRK05707 174 L 174
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
74-155 |
3.47e-04 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 40.57 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVREKVKnfaqltvsgsrsDGKPCppfkI 146
Cdd:cd19527 29 ILLYGPPGTGKTLLAKAIATEcslnflsVKGPELINMYIGE----SEANVREVFQKAR------------DAKPC----V 88
|
....*....
gi 4506491 147 VILDEADSM 155
Cdd:cd19527 89 IFFDELDSL 97
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
74-169 |
3.47e-04 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 40.74 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVREKVKNFAqltvsgsrsdgkPCppfkI 146
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEaganflsISGPSIVSKYLGE----SEKNLREIFEEARSHA------------PS----I 96
|
90 100
....*....|....*....|...
gi 4506491 147 VILDEADSMTSaAQAALRRTMEK 169
Cdd:cd19503 97 IFIDEIDALAP-KREEDQREVER 118
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
47-169 |
4.03e-04 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 40.47 E-value: 4.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 47 KCVDEVafqEEVVAVLKKSLE-----GADLPN-LLFYGPPGTGKTSTILAAARELFGPeLFRLRVLEL-----NASDERg 115
Cdd:cd19518 7 STLKEL---CELLIHPILPPEyfqhlGVEPPRgVLLHGPPGCGKTMLANAIAGELKVP-FLKISATEIvsgvsGESEEK- 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 4506491 116 IQVVREKVKNFAqltvsgsrsdgkPCppfkIVILDEADSMTSAAQAAlRRTMEK 169
Cdd:cd19518 82 IRELFDQAISNA------------PC----IVFIDEIDAITPKRESA-QREMER 118
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
208-267 |
4.42e-04 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 38.25 E-value: 4.42e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 208 QQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKeITEKVITDIAG 267
Cdd:cd18137 7 VGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGR-VTLDDVREMLG 65
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
74-158 |
4.42e-04 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 40.57 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVREKVKNFAqltvsgsrsdgkPCppfkI 146
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANEcqanfisVKGPELLTMWFGE----SEANVRDIFDKARAAA------------PC----V 89
|
90
....*....|..
gi 4506491 147 VILDEADSMTSA 158
Cdd:cd19528 90 LFFDELDSIAKA 101
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
78-106 |
5.30e-04 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 39.53 E-value: 5.30e-04
10 20
....*....|....*....|....*....
gi 4506491 78 GPPGTGKTSTILAAARELFGPELFRlRVL 106
Cdd:cd17934 6 GPPGTGKTTTIAAIVLQLLKGLRGK-RVL 33
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
55-95 |
6.58e-04 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 40.68 E-value: 6.58e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 4506491 55 QEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL 95
Cdd:cd18038 4 DEQKLAVRNIVTGTSRPPPYIIFGPPGTGKTVTLVEAILQV 44
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
75-95 |
7.41e-04 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 39.64 E-value: 7.41e-04
10 20
....*....|....*....|.
gi 4506491 75 LFYGPPGTGKTSTILAAAREL 95
Cdd:cd19510 27 LLYGPPGTGKSSFIAALAGEL 47
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
68-156 |
9.12e-04 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 39.39 E-value: 9.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 68 GADLP-NLLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVREKVKNFAqltvsgsrsdgk 139
Cdd:cd19530 26 GIDLPtGVLLYGPPGCGKTLLAKAVANEsganfisVKGPELLNKYVGE----SERAVRQVFQRARASA------------ 89
|
90
....*....|....*..
gi 4506491 140 PCppfkIVILDEADSMT 156
Cdd:cd19530 90 PC----VIFFDEVDALV 102
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
74-179 |
9.87e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 38.86 E-value: 9.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARELfgpELFRLRVLELNASDERGIQVVREKVknFAQLTVSGSRSDGKP------------C 141
Cdd:pfam13401 8 LVLTGESGTGKTTLLRRLLEQL---PEVRDSVVFVDLPSGTSPKDLLRAL--LRALGLPLSGRLSKEellaalqqlllaL 82
|
90 100 110
....*....|....*....|....*....|....*...
gi 4506491 142 PPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLI 179
Cdd:pfam13401 83 AVAVVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| DEXXQc_HELZ2-N |
cd18076 |
N-terminal DEXXQ-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known ... |
55-95 |
1.21e-03 |
|
N-terminal DEXXQ-box helicase domain of HELZ2; Helicase with zinc finger 2 (HELZ2, also known as PPAR-alpha-interacting complex protein 285 or PRIC285 and PPAR-gamma DBD-interacting protein 1 or PDIP1) acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB, and RXRA. It belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350834 [Multi-domain] Cd Length: 230 Bit Score: 39.87 E-value: 1.21e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 4506491 55 QEEVVA-VLKKSLEGADLPNLLFYGPPGTGKTSTILAAAREL 95
Cdd:cd18076 6 QQLAFNfIAGKPSEARFVPPLLIYGPFGTGKTFTLAMAALEV 47
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
50-114 |
1.31e-03 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 39.08 E-value: 1.31e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 4506491 50 DEVAFQEE----VVAVLKKSLEGADLPN-----LLFYGPPGTGKTSTILAAARELFGPELFRLRVlELNASDER 114
Cdd:cd19499 11 ERVVGQDEavkaVSDAIRRARAGLSDPNrpigsFLFLGPTGVGKTELAKALAELLFGDEDNLIRI-DMSEYMEK 83
|
|
| RecA-like_Lon |
cd19500 |
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ... |
57-105 |
1.50e-03 |
|
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410908 [Multi-domain] Cd Length: 182 Bit Score: 39.08 E-value: 1.50e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 4506491 57 EVVAV--LKKSLEGadlPNLLFYGPPGTGKTSTILAAARELfGPELFRLRV 105
Cdd:cd19500 24 EYLAVrkLKGSMKG---PILCLVGPPGVGKTSLGKSIARAL-GRKFVRISL 70
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
144-201 |
1.70e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 39.79 E-value: 1.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 144 FKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKP 201
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTP 166
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
56-92 |
4.80e-03 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 38.88 E-value: 4.80e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 4506491 56 EEVVAVLKKS----LEGADLPN-LLFYGPPGTGKtsTILAAA 92
Cdd:CHL00176 196 EEVVSFLKKPerftAVGAKIPKgVLLVGPPGTGK--TLLAKA 235
|
|
| Lon |
COG0466 |
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, ... |
60-86 |
5.00e-03 |
|
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440234 [Multi-domain] Cd Length: 785 Bit Score: 38.84 E-value: 5.00e-03
10 20
....*....|....*....|....*....
gi 4506491 60 AV--LKKSLEGadlPNLLFYGPPGTGKTS 86
Cdd:COG0466 342 AVrkLKKKLKG---PILCLVGPPGVGKTS 367
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
55-261 |
6.19e-03 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 38.05 E-value: 6.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 55 QEEVVAVLKKSLEGAD-----LPNLLFYGPPGTGKTStilaaarelfgpeLFRLRVLELNASdergIQV----VREKVKN 125
Cdd:TIGR00635 9 QEKVKEQLQLFIEAAKmrqeaLDHLLLYGPPGLGKTT-------------LAHIIANEMGVN----LKItsgpALEKPGD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 126 FAQLTVSGSRSDgkpcppfkIVILDEADSMTSAAQAALRRTMEK-----------ESKTTR-----FCLI--CNYVSRII 187
Cdd:TIGR00635 72 LAAILTNLEEGD--------VLFIDEIHRLSPAVEELLYPAMEDfrldivigkgpSARSVRldlppFTLVgaTTRAGMLT 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506491 188 EPLTSRCS-KFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFL---QSATRLTGGKEITEKV 261
Cdd:TIGR00635 144 SPLRDRFGiILRLEFYTVEELAEIVSRSAGLLNVEIEPEAALEIARRSRGTPRIANRLLrrvRDFAQVRGQKIINRDI 221
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
75-192 |
6.66e-03 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 37.96 E-value: 6.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 75 LFYGPPGTGKTSTIL------AAARELFGPELFRLRVLELNAsdERGIQVVREKVKNFAQltvsgSRSDGKPCPPFKIVI 148
Cdd:COG3598 17 LLAGPPGTGKSFLALqlaaavAAGGPWLGRRVPPGKVLYLAA--EDDRGELRRRLKALGA-----DLGLPFADLDGRLRL 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 4506491 149 LDEADSMTSaaqAALRRTMEKESKTTRFCLIcnyvsrIIEPLTS 192
Cdd:COG3598 90 LSLAGDLDD---TDDLEALERAIEEEGPDLV------VIDPLAR 124
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
56-165 |
6.90e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 37.10 E-value: 6.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 56 EEVVAVLKKSLEGaDLPNLLFYGPPGTGKTSTILAAARELFGPelfRLRVLELNASDERGIQVVREKVKNFAQLTVSGSR 135
Cdd:pfam13191 10 EQLLDALDRVRSG-RPPSVLLTGEAGTGKTTLLRELLRALERD---GGYFLRGKCDENLPYSPLLEALTREGLLRQLLDE 85
|
90 100 110
....*....|....*....|....*....|
gi 4506491 136 SDGKPCPPFKIVILDEADSMTSAAQAALRR 165
Cdd:pfam13191 86 LESSLLEAWRAALLEALAPVPELPGDLAER 115
|
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
74-155 |
8.43e-03 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 36.70 E-value: 8.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 74 LLFYGPPGTGKTSTILAAARE-------LFGPELFRLRVLElnasDERGIQVVREKVKNFAqltvsgsrsdgkPCppfkI 146
Cdd:cd19529 30 ILLYGPPGTGKTLLAKAVATEsnanfisVKGPELLSKWVGE----SEKAIREIFRKARQVA------------PC----V 89
|
....*....
gi 4506491 147 VILDEADSM 155
Cdd:cd19529 90 IFFDEIDSI 98
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
78-162 |
8.44e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 36.38 E-value: 8.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506491 78 GPPGTGKTsTILAAARELFGPELFRLRVLelnASDERGIQVVREKVKNFAQlTV----------SGSRSDGKPCPPFKIV 147
Cdd:cd17933 19 GGAGTGKT-TTLKALLAALEAEGKRVVLA---APTGKAAKRLSESTGIEAS-TIhrllginpggGGFYYNEENPLDADLL 93
|
90
....*....|....*
gi 4506491 148 ILDEAdSMTSAAQAA 162
Cdd:cd17933 94 IVDEA-SMVDTRLMA 107
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
53-106 |
9.94e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 37.70 E-value: 9.94e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 4506491 53 AFQEEVVAVLKKSLEGADlPNLLFYGPPGTGKTSTILAAARELFGPElfrlRVL 106
Cdd:COG1061 83 PYQQEALEALLAALERGG-GRGLVVAPTGTGKTVLALALAAELLRGK----RVL 131
|
|
| |
