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Conserved domains on  [gi|7262378|ref|NP_004205|]
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acidic fibroblast growth factor intracellular-binding protein isoform b [Homo sapiens]

Protein Classification

FIBP domain-containing protein( domain architecture ID 10527117)

FIBP domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FIBP pfam05427
Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) ...
3-356 0e+00

Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) intracellular binding protein (FIBP) is a protein found mainly in the nucleus that is thought to be involved in the intracellular function of aFGF.


:

Pssm-ID: 461649  Cd Length: 360  Bit Score: 607.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378      3 SELDIFVGNTTLIDEDVYRLWLDGYSVTDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIF 82
Cdd:pfam05427   1 TEVDVFVGNYTLIDPEVYQLWLDGYSVSDAVSILQQSGILQQTGASLDLLASDVLDHYRTFQLLERLLHSPPKLAEQLLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378     83 QIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQH 162
Cdd:pfam05427  81 QIEPQTQRLLIEKYYEFDDVVVREILGKKLSSRHRKDLDEVSEKTGIALKSCRRQFDNVKRVFKAVEEMPGPLVNNIQQH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    163 FLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQMDDMDMD-LDKEFLQDLKELKVLV 241
Cdd:pfam05427 161 FLLSEDLAKKYAAIVFIANNRFETGKKKLQYLTFSDFYFCAHQMMNNWTYGAVDSGVDHDMDVdLDKEFLQDLRELKVLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    242 aDKDLLDLHKSLVCTALRGKL--GVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRF 319
Cdd:pfam05427 241 -DKEVLDEHKHLVCSALKGKLleRSYQELEANFKNLSRAIINIACNLHRSKELRDLFVDLVEKFIEPCRQAGWTKSDLEL 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 7262378    320 FLNQYSASVHSLDGFRH----QALWDRYMGTLRGCLLRLYH 356
Cdd:pfam05427 320 FLKAYTQSALELDVFRDlphlKAVWERYMDTLTSCLLQMYH 360
 
Name Accession Description Interval E-value
FIBP pfam05427
Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) ...
3-356 0e+00

Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) intracellular binding protein (FIBP) is a protein found mainly in the nucleus that is thought to be involved in the intracellular function of aFGF.


Pssm-ID: 461649  Cd Length: 360  Bit Score: 607.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378      3 SELDIFVGNTTLIDEDVYRLWLDGYSVTDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIF 82
Cdd:pfam05427   1 TEVDVFVGNYTLIDPEVYQLWLDGYSVSDAVSILQQSGILQQTGASLDLLASDVLDHYRTFQLLERLLHSPPKLAEQLLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378     83 QIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQH 162
Cdd:pfam05427  81 QIEPQTQRLLIEKYYEFDDVVVREILGKKLSSRHRKDLDEVSEKTGIALKSCRRQFDNVKRVFKAVEEMPGPLVNNIQQH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    163 FLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQMDDMDMD-LDKEFLQDLKELKVLV 241
Cdd:pfam05427 161 FLLSEDLAKKYAAIVFIANNRFETGKKKLQYLTFSDFYFCAHQMMNNWTYGAVDSGVDHDMDVdLDKEFLQDLRELKVLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    242 aDKDLLDLHKSLVCTALRGKL--GVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRF 319
Cdd:pfam05427 241 -DKEVLDEHKHLVCSALKGKLleRSYQELEANFKNLSRAIINIACNLHRSKELRDLFVDLVEKFIEPCRQAGWTKSDLEL 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 7262378    320 FLNQYSASVHSLDGFRH----QALWDRYMGTLRGCLLRLYH 356
Cdd:pfam05427 320 FLKAYTQSALELDVFRDlphlKAVWERYMDTLTSCLLQMYH 360
 
Name Accession Description Interval E-value
FIBP pfam05427
Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) ...
3-356 0e+00

Acidic fibroblast growth factor binding (FIBP); Acidic fibroblast growth factor (aFGF) intracellular binding protein (FIBP) is a protein found mainly in the nucleus that is thought to be involved in the intracellular function of aFGF.


Pssm-ID: 461649  Cd Length: 360  Bit Score: 607.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378      3 SELDIFVGNTTLIDEDVYRLWLDGYSVTDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIF 82
Cdd:pfam05427   1 TEVDVFVGNYTLIDPEVYQLWLDGYSVSDAVSILQQSGILQQTGASLDLLASDVLDHYRTFQLLERLLHSPPKLAEQLLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378     83 QIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQH 162
Cdd:pfam05427  81 QIEPQTQRLLIEKYYEFDDVVVREILGKKLSSRHRKDLDEVSEKTGIALKSCRRQFDNVKRVFKAVEEMPGPLVNNIQQH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    163 FLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQMDDMDMD-LDKEFLQDLKELKVLV 241
Cdd:pfam05427 161 FLLSEDLAKKYAAIVFIANNRFETGKKKLQYLTFSDFYFCAHQMMNNWTYGAVDSGVDHDMDVdLDKEFLQDLRELKVLL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7262378    242 aDKDLLDLHKSLVCTALRGKL--GVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRF 319
Cdd:pfam05427 241 -DKEVLDEHKHLVCSALKGKLleRSYQELEANFKNLSRAIINIACNLHRSKELRDLFVDLVEKFIEPCRQAGWTKSDLEL 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 7262378    320 FLNQYSASVHSLDGFRH----QALWDRYMGTLRGCLLRLYH 356
Cdd:pfam05427 320 FLKAYTQSALELDVFRDlphlKAVWERYMDTLTSCLLQMYH 360
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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