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Conserved domains on  [gi|4758316|ref|NP_004445|]
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ETS translocation variant 5 [Homo sapiens]

Protein Classification

ETS translocation variant( domain architecture ID 12054215)

ETS translocation variant (ETV) is a transcriptional activator that binds to consensus DNA sequences, such as human ETV1 that binds to the pentanucleotide 5'-CGGA[AT]-3'

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ETS_PEA3_N pfam04621
PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 ...
 1-366 0e+00

PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 transcription factors is implicated in transactivation and in inhibition of DNA binding. Transactivation is potentiated by activation of the Ras/MAP kinase and protein kinase A signalling cascades. The N terminal region contains conserved MAP kinase phosphorylation sites.


:

Pssm-ID: 461371  Cd Length: 344  Bit Score: 516.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316      1 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVL 80
Cdd:pfam04621   1 MDGFYDQQVPFMVPGSSCGEGPLGRPLMDRKRKFMDTELAQDSEELFQDLSQLQETWLAEAQVPDDEQFVPDFQSENLAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     81 HAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKPPSGFKpltppttplspthqnPLFPPPQATLPTS 160
Cdd:pfam04621  81 HGPPPAKIKREPQSPSSDLSSCSHEQSFKYPYGEQCLYNYSAYDRKPPSGFK---------------PPTPPSTPVSPLQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    161 GHAPAAGPVQGVGPAPAPHSLpepgpQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNR 240
Cdd:pfam04621 146 QHSSLKTPPLQRQPSPLPLMR-----QSPPFAVPRPPRGYMPMPPSQPSNSYPIEHRFQRQLSEPCLPFPPPEGGPRDGR 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    241 PSYHRQMSEPIVpaaPPPPQGFKQEYHDPLYEHGvPGMPGPPAHGFQSPMGIKQEPRDYCVDSEVPNCQSSYMR--GGYF 318
Cdd:pfam04621 221 PPYQRQMSEPLV---PYPPQGFKQEYHDPLYEHG-PPPGGPPPHRFPPPMMIKQEPRDYGYDSEVPNCQSSYGRseGFLY 296

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 4758316    319 SSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRG 366
Cdd:pfam04621 297 PNSHDGFSYDKDPRLFYDDTCVVPEKLEGKVKQEPGVYREGPPYQRRG 344
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 367-452 1.15e-49

erythroblast transformation specific domain; variation of the helix-turn-helix motif


:

Pssm-ID: 197710  Cd Length: 87  Bit Score: 165.13  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     367 SLQLWQFLVTLLDDPANAHFIAWTGR-GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVY 445
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRdEGEFKLVDPEEVARLWGQRKNKPNMNYEKLSRALRYYYKKNILEKVPGKRLVY 80


                   ....*..
gi 4758316     446 KFVCDPD 452
Cdd:smart00413  81 KFVKNPL 87
 
Name Accession Description Interval E-value
ETS_PEA3_N pfam04621
PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 ...
 1-366 0e+00

PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 transcription factors is implicated in transactivation and in inhibition of DNA binding. Transactivation is potentiated by activation of the Ras/MAP kinase and protein kinase A signalling cascades. The N terminal region contains conserved MAP kinase phosphorylation sites.


Pssm-ID: 461371  Cd Length: 344  Bit Score: 516.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316      1 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVL 80
Cdd:pfam04621   1 MDGFYDQQVPFMVPGSSCGEGPLGRPLMDRKRKFMDTELAQDSEELFQDLSQLQETWLAEAQVPDDEQFVPDFQSENLAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     81 HAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKPPSGFKpltppttplspthqnPLFPPPQATLPTS 160
Cdd:pfam04621  81 HGPPPAKIKREPQSPSSDLSSCSHEQSFKYPYGEQCLYNYSAYDRKPPSGFK---------------PPTPPSTPVSPLQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    161 GHAPAAGPVQGVGPAPAPHSLpepgpQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNR 240
Cdd:pfam04621 146 QHSSLKTPPLQRQPSPLPLMR-----QSPPFAVPRPPRGYMPMPPSQPSNSYPIEHRFQRQLSEPCLPFPPPEGGPRDGR 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    241 PSYHRQMSEPIVpaaPPPPQGFKQEYHDPLYEHGvPGMPGPPAHGFQSPMGIKQEPRDYCVDSEVPNCQSSYMR--GGYF 318
Cdd:pfam04621 221 PPYQRQMSEPLV---PYPPQGFKQEYHDPLYEHG-PPPGGPPPHRFPPPMMIKQEPRDYGYDSEVPNCQSSYGRseGFLY 296

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 4758316    319 SSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRG 366
Cdd:pfam04621 297 PNSHDGFSYDKDPRLFYDDTCVVPEKLEGKVKQEPGVYREGPPYQRRG 344
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 367-452 1.15e-49

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 165.13  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     367 SLQLWQFLVTLLDDPANAHFIAWTGR-GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVY 445
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRdEGEFKLVDPEEVARLWGQRKNKPNMNYEKLSRALRYYYKKNILEKVPGKRLVY 80


                   ....*..
gi 4758316     446 KFVCDPD 452
Cdd:smart00413  81 KFVKNPL 87
Ets pfam00178
Ets-domain;
369-447 1.00e-43

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 149.18  E-value: 1.00e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    369 QLWQFLVTLLDDPANAHFIAWTGR-GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 447
Cdd:pfam00178   1 QLWQFLLDLLTDPEYSDIIKWTDKeEGEFRLVDPEAVARLWGKRKGNPKMTYEKLSRALRYYYKKGILEKVPGKRLTYRF 80
PHA03247 PHA03247
large tegument protein UL36; Provisional
 151-236 1.68e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    151 PPPQATLPTSGHAPAAGPVQGVGPAPAP------------HSLPEPGPQQQTFAVPRPPHQPLQMPKmmPENQYPSEQRF 218
Cdd:PHA03247 2844 GPPPPSLPLGGSVAPGGDVRRRPPSRSPaakpaaparppvRRLARPAVSRSTESFALPPDQPERPPQ--PQAPPPPQPQP 2921

                          90
                  ....*....|....*...
gi 4758316    219 QRQLSEPCHPFPPQPGVP 236
Cdd:PHA03247 2922 QPPPPPQPQPPPPPPPRP 2939
 
Name Accession Description Interval E-value
ETS_PEA3_N pfam04621
PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 ...
 1-366 0e+00

PEA3 subfamily ETS-domain transcription factor N terminal domain; The N terminus of the PEA3 transcription factors is implicated in transactivation and in inhibition of DNA binding. Transactivation is potentiated by activation of the Ras/MAP kinase and protein kinase A signalling cascades. The N terminal region contains conserved MAP kinase phosphorylation sites.


Pssm-ID: 461371  Cd Length: 344  Bit Score: 516.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316      1 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVL 80
Cdd:pfam04621   1 MDGFYDQQVPFMVPGSSCGEGPLGRPLMDRKRKFMDTELAQDSEELFQDLSQLQETWLAEAQVPDDEQFVPDFQSENLAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     81 HAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKPPSGFKpltppttplspthqnPLFPPPQATLPTS 160
Cdd:pfam04621  81 HGPPPAKIKREPQSPSSDLSSCSHEQSFKYPYGEQCLYNYSAYDRKPPSGFK---------------PPTPPSTPVSPLQ 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    161 GHAPAAGPVQGVGPAPAPHSLpepgpQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNR 240
Cdd:pfam04621 146 QHSSLKTPPLQRQPSPLPLMR-----QSPPFAVPRPPRGYMPMPPSQPSNSYPIEHRFQRQLSEPCLPFPPPEGGPRDGR 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    241 PSYHRQMSEPIVpaaPPPPQGFKQEYHDPLYEHGvPGMPGPPAHGFQSPMGIKQEPRDYCVDSEVPNCQSSYMR--GGYF 318
Cdd:pfam04621 221 PPYQRQMSEPLV---PYPPQGFKQEYHDPLYEHG-PPPGGPPPHRFPPPMMIKQEPRDYGYDSEVPNCQSSYGRseGFLY 296

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 4758316    319 SSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRG 366
Cdd:pfam04621 297 PNSHDGFSYDKDPRLFYDDTCVVPEKLEGKVKQEPGVYREGPPYQRRG 344
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 367-452 1.15e-49

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 165.13  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316     367 SLQLWQFLVTLLDDPANAHFIAWTGR-GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVY 445
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRdEGEFKLVDPEEVARLWGQRKNKPNMNYEKLSRALRYYYKKNILEKVPGKRLVY 80


                   ....*..
gi 4758316     446 KFVCDPD 452
Cdd:smart00413  81 KFVKNPL 87
Ets pfam00178
Ets-domain;
369-447 1.00e-43

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 149.18  E-value: 1.00e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    369 QLWQFLVTLLDDPANAHFIAWTGR-GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 447
Cdd:pfam00178   1 QLWQFLLDLLTDPEYSDIIKWTDKeEGEFRLVDPEAVARLWGKRKGNPKMTYEKLSRALRYYYKKGILEKVPGKRLTYRF 80
PHA03247 PHA03247
large tegument protein UL36; Provisional
 151-236 1.68e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    151 PPPQATLPTSGHAPAAGPVQGVGPAPAP------------HSLPEPGPQQQTFAVPRPPHQPLQMPKmmPENQYPSEQRF 218
Cdd:PHA03247 2844 GPPPPSLPLGGSVAPGGDVRRRPPSRSPaakpaaparppvRRLARPAVSRSTESFALPPDQPERPPQ--PQAPPPPQPQP 2921

                          90
                  ....*....|....*...
gi 4758316    219 QRQLSEPCHPFPPQPGVP 236
Cdd:PHA03247 2922 QPPPPPQPQPPPPPPPRP 2939
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 153-250 5.74e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.85  E-value: 5.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    153 PQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPR---PPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPF 229
Cdd:PRK10263  740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQqpvAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ 819

                          90       100
                  ....*....|....*....|.
gi 4758316    230 PPQPGVPgdnRPSYHRQMSEP 250
Cdd:PRK10263  820 PQQPVAP---QPQYQQPQQPV 837
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 150-241 5.14e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.76  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    150 FPPPQATLPTSGHAPAAGPvqGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPK--MMPENQYPSEQR---FQRQLSE 224
Cdd:PRK10263  729 FSPMKALLDDGPHEPLFTP--IVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQqpVAPQPQYQQPQQpvaPQPQYQQ 806

                          90
                  ....*....|....*..
gi 4758316    225 PCHPFPPQPGVPGDNRP 241
Cdd:PRK10263  807 PQQPVAPQPQYQQPQQP 823
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 146-289 8.10e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 42.06  E-value: 8.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    146 QNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAvPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEP 225
Cdd:pfam03154 177 QSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQS-TAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQP 255

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    226 CHPFP------PQPGVPGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSP 289
Cdd:pfam03154 256 PPPSQvspqplPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI 325
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 197-298 1.02e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.99  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    197 PHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNRP-SYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGV 275
Cdd:PRK10263  740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPvAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ 819

                          90       100
                  ....*....|....*....|....
gi 4758316    276 PGMPGPPAHGFQSPMG-IKQEPRD 298
Cdd:PRK10263  820 PQQPVAPQPQYQQPQQpVAPQPQD 843
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 162-291 1.13e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.56  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    162 HAPAAGPVQGVGPAPAPHSLPEP--GPQQQTFAVPRPPHQPLQMPKMMP--ENQYPSEQRFQRQLSEPCHPFPPQPG-VP 236
Cdd:pfam09770 206 QAKKPAQQPAPAPAQPPAAPPAQqaQQQQQFPPQIQQQQQPQQQPQQPQqhPGQGHPVTILQRPQSPQPDPAQPSIQpQA 285

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 4758316    237 GDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMG 291
Cdd:pfam09770 286 QQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFG 340
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 151-250 1.29e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316   151 PPPQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRfQRQLSEPCHPFP 230
Cdd:PRK07764 392 GAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP-AAAPSAQPAPAP 470

                         90       100
                 ....*....|....*....|
gi 4758316   231 PQPGVPGDNRPSYHRQMSEP 250
Cdd:PRK07764 471 AAAPEPTAAPAPAPPAAPAP 490
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 153-296 1.66e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    153 PQATLPTSgHAPAAGPVQGVGPAPAPHS-------LPEPGPQQQTFAVPRPPHQ-PLQMPkMMPENQYPSEQRFQRQLSE 224
Cdd:PRK10263  342 QTPPVASV-DVPPAQPTVAWQPVPGPQTgepviapAPEGYPQQSQYAQPAVQYNePLQQP-VQPQQPYYAPAAEQPAQQP 419

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4758316    225 PCHPFPPQPGvpgdNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGM-PGPPAHGFQSPMGIKQEP 296
Cdd:PRK10263  420 YYAPAPEQPA----QQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQqPAAQEPLYQQPQPVEQQP 488
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 151-287 2.65e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 40.40  E-value: 2.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    151 PPPQATLPTSGHAPAAGP-VQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPF 229
Cdd:pfam09770 209 KPAQQPAPAPAQPPAAPPaQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQF 288

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4758316    230 PPQPGVPGD---------NRPSYHRQmsepivpaappppqgfkqeyhdPLYEHGVPGMPGPPAHGFQ 287
Cdd:pfam09770 289 HQQPPPVPVqptqilqnpNRLSAARV----------------------GYPQNPQPGVQPAPAHQAH 333
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
151-252 3.79e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 3.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316   151 PPPQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPkmmPENQYPSEQRFQRQLSEPCHPFP 230
Cdd:PRK12323 427 SPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAP---ARAAPAAAPAPADDDPPPWEELP 503

                         90       100
                 ....*....|....*....|....
gi 4758316   231 PQPGVPG--DNRPSYHRQMSEPIV 252
Cdd:PRK12323 504 PEFASPApaQPDAAPAGWVAESIP 527
PHA03247 PHA03247
large tegument protein UL36; Provisional
 148-289 6.89e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 6.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    148 PLFPPPQAT--LPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEP 225
Cdd:PHA03247 2589 PDAPPQSARprAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRAR 2668

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4758316    226 CHPFPPQPGVPGDN-RPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSP 289
Cdd:PHA03247 2669 RLGRAAQASSPPQRpRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASP 2733
PHA03247 PHA03247
large tegument protein UL36; Provisional
 125-242 8.45e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 8.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4758316    125 RKPPSGFkpltppttplspthqnplfPPPQATLPTSghaPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMP 204
Cdd:PHA03247 2864 RRPPSRS-------------------PAAKPAAPAR---PPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQP 2921

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 4758316    205 kmmPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNRPS 242
Cdd:PHA03247 2922 ---QPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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