|
Name |
Accession |
Description |
Interval |
E-value |
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
19-332 |
0e+00 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 588.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 19 VDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLST 98
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 99 GSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPES 178
Cdd:TIGR02238 81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 179 CLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVF 258
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVAVF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6321027 259 LTNQVQSDPGASALFASaDGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDS 332
Cdd:TIGR02238 241 VTNQVQADPGATMTFIA-DPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
6-334 |
5.80e-177 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 493.36 E-value: 5.80e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 6 TEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATV 85
Cdd:PTZ00035 10 EEEEEEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVPMGFISATE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 86 QLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERI 165
Cdd:PTZ00035 90 YLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 166 KQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFK 245
Cdd:PTZ00035 170 VQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQHLGKFLRA 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 246 LNRLAEEFNVAVFLTNQVQSDPGASALFAsADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIG 325
Cdd:PTZ00035 250 LQKLADEFNVAVVITNQVMADVDGASMFV-ADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPESEAVFAIS 328
|
....*....
gi 6321027 326 EKGITDSSD 334
Cdd:PTZ00035 329 EGGIIDAKD 337
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
78-331 |
2.35e-160 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 447.90 E-value: 2.35e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 78 VGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTE 157
Cdd:pfam08423 1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 158 GTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQ 237
Cdd:pfam08423 81 GTFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 238 KLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPE 317
Cdd:pfam08423 161 HLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPE 240
|
250
....*....|....
gi 6321027 318 KECVYVIGEKGITD 331
Cdd:pfam08423 241 SEAVFAIGSGGIID 254
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
96-331 |
4.97e-158 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 441.41 E-value: 4.97e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELD 175
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLGEELS-SGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFN 254
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHeEAVFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6321027 255 VAVFLTNQVQSDPGASALFAsADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITD 331
Cdd:cd19514 161 VAVFITNQVTADPGAAMTFQ-ADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
18-334 |
9.73e-152 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 429.97 E-value: 9.73e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 18 SVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLS 97
Cdd:PLN03187 30 SIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQGFITGSDALLKRKSVVRIT 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 98 TGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPE 177
Cdd:PLN03187 110 TGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIAERFGMDAD 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 178 SCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAV 257
Cdd:PLN03187 190 AVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTGRGELAERQQKLAQMLSRLTKIAEEFNVAV 269
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6321027 258 FLTNQVQSDPGASAlFASaDGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD 334
Cdd:PLN03187 270 YMTNQVIADPGGGM-FIS-DPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEAEAEFQITSGGIMDAKD 344
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
11-334 |
6.82e-147 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 417.60 E-value: 6.82e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 11 DTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIR 90
Cdd:PLN03186 20 EAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPLGFTTASQLHAQR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 91 QRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAE 170
Cdd:PLN03186 100 QEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQIAE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 171 GYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLA 250
Cdd:PLN03186 180 RFGLNGADVLENVAYARAYNTDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSGRGELSARQMHLGKFLRSLQRLA 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 251 EEFNVAVFLTNQVQSDPGASALFASADgRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGIT 330
Cdd:PLN03186 260 DEFGVAVVITNQVVAQVDGSAFFAGPQ-LKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCLPEAEARFSISSEGVT 338
|
....
gi 6321027 331 DSSD 334
Cdd:PLN03186 339 DVKD 342
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
19-334 |
2.87e-145 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 412.20 E-value: 2.87e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 19 VDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLST 98
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 99 GSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPES 178
Cdd:TIGR02239 81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 179 CLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVF 258
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6321027 259 LTNQVQSDP-GASALFAsADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD 334
Cdd:TIGR02239 241 ITNQVVAQVdGAGSMFA-GDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
13-331 |
1.01e-131 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 378.07 E-value: 1.01e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 13 AKNILSVDELQnyGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQV-GFIPATVQLDIRQ 91
Cdd:PRK04301 2 KMKEKDLEDLP--GVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADIgGFETALEVLERRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 92 RVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEG 171
Cdd:PRK04301 80 NVGKITTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 172 YELDPESCLANVSYARALNSEHQMELVEQLgEELSSGDY--RLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRL 249
Cdd:PRK04301 160 LGLDPDEVLDNIHVARAYNSDHQMLLAEKA-EELIKEGEniKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 250 AEEFNVAVFLTNQVQSDPGasALFasADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGI 329
Cdd:PRK04301 239 ADLYNAAVVVTNQVMARPD--AFF--GDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGI 314
|
..
gi 6321027 330 TD 331
Cdd:PRK04301 315 RD 316
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
96-331 |
2.09e-126 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 361.25 E-value: 2.09e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELD 175
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNV 255
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6321027 256 AVFLTNQVQSDPGASALFAsADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITD 331
Cdd:cd19513 161 AVVITNQVVAQVDGAAMFA-GDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
96-329 |
7.35e-122 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 349.91 E-value: 7.35e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELD 175
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNV 255
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6321027 256 AVFLTNQVQSDPGASALFAsADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGI 329
Cdd:cd01123 161 AVVVTNQVVAQVDGAMMFA-ADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGV 233
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
26-331 |
1.87e-121 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 351.74 E-value: 1.87e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 26 GINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVG-FIPATVQLDIRQRVYSLSTGSKQLD 104
Cdd:TIGR02236 6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 105 SILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVS 184
Cdd:TIGR02236 86 ELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 185 YARALNSEHQMELVEQLGEELSSGDY--RLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQ 262
Cdd:TIGR02236 166 VARAYNSNHQMLLVEKAEDLIKELNNpvKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQ 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6321027 263 VQSDPgaSALFasADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITD 331
Cdd:TIGR02236 246 VMARP--DAFF--GDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
96-331 |
3.92e-116 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 335.10 E-value: 3.92e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELD 175
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLGEELSSGD-YRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFN 254
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNnIKLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6321027 255 VAVFLTNQVQSDPgaSALFasADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITD 331
Cdd:cd19515 161 IAVLVTNQVMAKP--DAFF--GDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
96-333 |
1.04e-46 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 157.72 E-value: 1.04e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTqmshTLCVttQLPREMGGGEGKVAYIDTEGtFRPERIKQIAEGyelD 175
Cdd:PRK09361 5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKT----NICL--QLAVEAAKNGKKVIYIDTEG-LSPERFKQIAGE---D 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLgEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNV 255
Cdd:PRK09361 75 FEELLSNIIIFEPSSFEEQSEAIRKA-EKLAKENVGLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTHLLKLARKHDL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6321027 256 AVFLTNQVQSDPGasalfasADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKE-CVYVIGEKGITDSS 333
Cdd:PRK09361 154 AVVITNQVYSDID-------SDGLRPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGEsAEFRITDRGIEIID 225
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
103-299 |
5.68e-45 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 153.99 E-value: 5.68e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 103 LDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYE-----LDPE 177
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLPkryhlEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 178 SCLANVSYARALNSEHQMELV-EQLGEELSSGDYRLIVVDSIMANFRVDY-CGRGELSERQQKLNQHLFKLNRLAEEFNV 255
Cdd:cd19491 81 NFLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYNL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6321027 256 AVFLTNQVQSDPGAS-----------ALFASADGRKPIG-------GHVLAHASATRILLRK 299
Cdd:cd19491 161 AVVVVNQVTDRFDSSsdasglgvldyLSQFSSFSGGVSGnrkvpalGLTWANLVNTRLMLSR 222
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
96-329 |
9.14e-45 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 152.47 E-value: 9.14e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTqmshTLCVTTQLprEMGGGEGKVAYIDTEGtFRPERIKQIAEGyelD 175
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKT----NICLQLAV--EAAKQGKKVVYIDTEG-LSPERFQQIAGE---R 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 PESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDycgRGELSERQQKLNQHLFKLNRLAEEFNV 255
Cdd:cd01394 71 FESIASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLE---LGDDSEANRELSRQMSKLLSIARKYDI 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6321027 256 AVFLTNQVQSDPGASALfasadgrKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPE-KECVYVIGEKGI 329
Cdd:cd01394 148 PVVITNQVYSDIDDDRL-------KPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEgQSAGFRITDRGI 215
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
115-299 |
3.11e-44 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 149.81 E-value: 3.11e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 115 SITEVFGEFRCGKTQMSHTLCVTTQLpremggGEGKVAYIDTEGTFRPERIKQIAEGY---ELDPESCLANVSYARALNS 191
Cdd:cd01393 2 KITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEASpssELELAEALSRLLYFRPPDT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 192 EHQMELVEQLGEEL-SSGDYRLIVVDSIMANFRVDY----CGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSD 266
Cdd:cd01393 76 LAHLLALDSLPESLfPPPNTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTK 155
|
170 180 190
....*....|....*....|....*....|....
gi 6321027 267 PGAsalfASADGR-KPIGGHVLAHASATRILLRK 299
Cdd:cd01393 156 IRG----GSGASLvPPALGNTWEHSVSTRLLLYR 185
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
104-305 |
1.09e-36 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 131.29 E-value: 1.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 104 DSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAE-----------GY 172
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAEarfpeafsgfmEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 173 ELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCG-RGELSERQQKLNQHLFKLNRLAE 251
Cdd:cd19493 81 NERAEEMLKRVAVVRVTTLAQLLERLPNLEEHILSSGVRLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLKRLAE 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 6321027 252 EFNVAVFLTNQVQSDPGASALFASADgrKPIGGHVLAHASATRILLRKGRGDER 305
Cdd:cd19493 161 EFRIAVLVTNQATTHFGDAGDGSSGV--TAALGDAWAHAVNTRLRLERCLLQLR 212
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
103-329 |
1.79e-34 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 125.22 E-value: 1.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 103 LDSILGGGIMTMSITEVFGEFRCGKTqmshTLCVTTQLPREMGGgeGKVAYIDTEGtFRPERIKQIAEGyelDPESCLAN 182
Cdd:TIGR02237 1 IDELLGGGVERGTITQIYGPPGSGKT----NICMILAVNAARQG--KKVVYIDTEG-LSPERFKQIAED---RPERALSN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 183 VSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDycGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQ 262
Cdd:TIGR02237 71 FIVFEVFDFDEQGVAIQKTSKFIDRDSASLVVVDSFTALYRLE--LSDDRISRNRELARQLTLLLSLARKKNLAVVITNQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6321027 263 VQSDPGASALfasadgrKPIGGHVLAHASATRILLRKGRGDeRVAKLQDSPDMPEKECVYV-IGEKGI 329
Cdd:TIGR02237 149 VYTDVNNGTL-------RPLGGHLLEHWSKVILRLEKFRGR-RLATLEKHRSRPEGESVYFrITDDGI 208
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
114-313 |
4.21e-33 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 120.41 E-value: 4.21e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 114 MSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFrperikqiaegyeldpesclaNVSYARALNSEH 193
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 194 QMELVEQLGEELSSG-DYRLIVVDSIMANFRVDYcgrGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQV--QSDPGAS 270
Cdd:cd19492 60 LLALINSLPKFLEDHpKVKLIVVDSIAFPFRHDF---DDLAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVttKISEDGQ 136
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 6321027 271 ALFASADGRKpigghvLAHASATRILLRKGrGDERVAKLQDSP 313
Cdd:cd19492 137 SQLVPALGES------WSHACTTRLFLTWD-EKQRFAHLYKSP 172
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
90-334 |
2.81e-27 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 109.49 E-value: 2.81e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 90 RQRVYSLSTGSKQLDSILG-GGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLpreMGGGegkVAYIDTEGTFRPERIKQI 168
Cdd:COG0468 38 RQDVEVISTGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEYAKKL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 169 aeGYELDpesclaNVSYARALNSEHQMELVEQLgeeLSSGDYRLIVVDSIMANFRVDYCgRGELSE-----RQQKLNQHL 243
Cdd:COG0468 112 --GVDID------NLLVSQPDTGEQALEIAETL---VRSGAVDLIVVDSVAALVPKAEI-EGEMGDshvglQARLMSQAL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 244 FKLNRLAEEFNVAVFLTNQVQSDPGasALFASADgrKPIGGHVLAHASATRILLRKG----RGDERV-----AKLQDS-- 312
Cdd:COG0468 180 RKLTGAISKSNTTVIFINQLREKIG--VMFGNPE--TTTGGNALKFYASVRLDIRRIgtikDGDEVIgnrtrVKVVKNkv 255
|
250 260
....*....|....*....|....
gi 6321027 313 -PdmPEKECVY-VIGEKGITDSSD 334
Cdd:COG0468 256 aP--PFKEAEFdIMYGEGISKEGE 277
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
108-299 |
5.62e-18 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 81.14 E-value: 5.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 108 GGGIMTMSITEVFGEFRCGKTQMSHTLCVttQLPREMGGGegkVAYIDTEGTFRPERIKQIAEG---YELDPESCLANVS 184
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAA--NVASRSGQN---VLYIDTKSSFSARRLAQILKSraqDAEEIDKALQRIR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 185 YARALNSEHQMELVEQLGEELS------SGDYRLIVVDSIMANFrVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVF 258
Cdd:cd19489 76 VVRVFDPYELLDLLEELRNTLSqqqenlYSRLKLVIIDSLSALI-SPLLGGSKHSEGHALLASLARLLKKLAAEYQIAVL 154
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 6321027 259 LTNQVQSDPGASALFasadGRKPIGGHVLAHASATRILLRK 299
Cdd:cd19489 155 VTNLTVRGGDGGQQG----STKPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
116-299 |
4.47e-13 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 67.37 E-value: 4.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 116 ITEVFGEFRCGKTQMSHTLCVTTQLPRE-----MGGGEGKVAYIDTEGTFRPERIKQIAEGY---------------ELD 175
Cdd:cd19490 3 VIEITGPSGSGKTELLYHLAARCILPSSwggvpLGGLEAAVVFIDTDGRFDILRLRSILEARiraaiqaanssddeeDVE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 176 P--ESCLANVSYARALNSEH---QMELVEQLGEELS-SGDYRLIVVDSIMANFRVDYCGRGELSERQQKLN----QHLFK 245
Cdd:cd19490 83 EiaRECLQRLHIFRCHSSLQllaTLLSLENYLLSLSaNPELGLLLIDSISAFYWQDRFSAELARAAPLLQEaalrAILRE 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6321027 246 LNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASAT----------RILLRK 299
Cdd:cd19490 163 LRRLRRRFQLVVIATKQALFPGKSASTDNPAANNAVSKASAPSHREYLprpwqrlvthRLVLSR 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
96-330 |
1.79e-11 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 63.01 E-value: 1.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTtqlpremGGGEG-KVAYIDTEgtFRPERIKQIAEGYEL 174
Cdd:COG0467 2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLAE-------GLRRGeKGLYVSFE--ESPEQLLRRAESLGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 175 DPESCLAN--VSYARALNSEHQM---ELVEQLGEELSSGDYRLIVVDSIMAnFRvdycgrgELSERQQKLNQHLFKLNRL 249
Cdd:COG0467 73 DLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGAKRVVIDSLSG-LL-------LALPDPERLREFLHRLLRY 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 250 AEEFNVAVFLTNQvqsdpgasalfaSADGRKPIGGHVLAHASATRILLRKGRGDE------RVAKLQDSP-DMPEKEcvY 322
Cdd:COG0467 145 LKKRGVTTLLTSE------------TGGLEDEATEGGLSYLADGVILLRYVELGGelrralSVLKMRGSAhDRTIRE--F 210
|
....*...
gi 6321027 323 VIGEKGIT 330
Cdd:COG0467 211 EITDGGIE 218
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
96-330 |
2.00e-09 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 56.89 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMShTLCVTTQLPRemggGEgKVAYIDTEGTfrPERIKQIAE--GYE 173
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFG-LQFLYAGAKN----GE-PGLFFTFEES--PERLLRNAKsfGWD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 174 LDPESCLANVSYARALNSEHQMELVEQLGEELSS----GDYRLIVVDSIMANFRvdycgrgeLSERQQKLNQHLFKLNRL 249
Cdd:cd01124 73 FDEMEDEGKLIIVDAPPTEAGRFSLDELLSRILSiiksFKAKRVVIDSLSGLRR--------AKEDQMRARRIVIALLNE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 250 AEEFNVAVFLTNQVQSDPGASALfasadgrkpiGGHVLAHASATRILLRKGRGDE------RVAKLQDSPDMPeKECVYV 323
Cdd:cd01124 145 LRAAGVTTIFTSEMRSFLSSESA----------GGGDVSFIVDGVILLRYVEIEGelrrtiRVLKMRGTGHDT-GTHPFE 213
|
....*..
gi 6321027 324 IGEKGIT 330
Cdd:cd01124 214 ITDKGIV 220
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
92-300 |
2.56e-08 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 53.71 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 92 RVYSLSTGSKQLDSILG-GGIMTMSITEVFGEFRCGKTqmshTLcvTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIae 170
Cdd:cd00983 1 DVEVIPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKT----TL--ALHAIAEAQKLGGTAAFIDAEHALDPEYAKKL-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 171 GYELDpesclaNVSYARALNSEHQMELVEQLgeeLSSGDYRLIVVDSIMANF-RVDYcgRGELSERQQKLN-----QHLF 244
Cdd:cd00983 73 GVDID------NLLVSQPDTGEQALEIADTL---IRSGAVDLIVVDSVAALVpKAEI--EGEMGDSHVGLQarlmsQALR 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 6321027 245 KLNRLAEEFNVAVFLTNQVQSDPGasALFASADgrKPIGGHVLAHASATRILLRKG 300
Cdd:cd00983 142 KLTGSLSKSKTTVIFINQLREKIG--VMFGNPE--TTTGGNALKFYASVRLDIRRI 193
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
90-299 |
2.63e-08 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 53.94 E-value: 2.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 90 RQRVYSLSTGSKQLDSILG-GGIMTMSITEVFGEFRCGKTQMS-HTLCvttqlprEMGGGEGKVAYIDTEgtfrperikq 167
Cdd:pfam00154 27 KLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTLAlHAIA-------EAQKAGGTAAFIDAE---------- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 168 iaegYELDPesclanvSYARAL-------------NSEHQMELVEQLgeeLSSGDYRLIVVDSIMA---NFRVDycgrGE 231
Cdd:pfam00154 90 ----HALDP-------VYAKKLgvdidnllvsqpdTGEQALEIADML---VRSGAIDLIVVDSVAAlvpKAEIE----GE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6321027 232 LSERQQKL-----NQHLFKLNRLAEEFNVAVFLTNQVQSDPGasALFASADgrKPIGGHVLAHASATRILLRK 299
Cdd:pfam00154 152 MGDSHVGLqarlmSQALRKLTGSISKSNTTVIFINQIREKIG--VMFGNPE--TTTGGRALKFYASVRLDIRR 220
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
149-317 |
3.53e-08 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 54.14 E-value: 3.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 149 GKVAYIDTEGTFRP--ERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDy 226
Cdd:COG3598 51 GKVLYLAAEDDRGElrRRLKALGADLGLPFADLDGRLRLLSLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFGGD- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 227 cgrgELSERQQK--LNQhlfkLNRLAEEFNVAVFL---TNQVQSDP-------GASALFASADgrkpigghvlahasATR 294
Cdd:COG3598 130 ----ENDAEEMRafLNP----LDRLAERTGAAVLLvhhTGKGGAGKdsgdrarGSSALRGAAR--------------SVL 187
|
170 180
....*....|....*....|...
gi 6321027 295 ILLRKGRGDERVAKLQDSPDMPE 317
Cdd:COG3598 188 VLSREKGEDLRVLTRAKSNYGPE 210
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
96-329 |
5.68e-05 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 43.77 E-value: 5.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPRemggGEgKVAYIDTEGTfrPERIKQIAE--GYE 173
Cdd:pfam06745 1 VKTGIPGLDEILKGGFPEGRVVLITGGPGTGKTIFGLQFLYNGALKY----GE-PGVFVTLEEP--PEDLRENARsfGWD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 174 LDP---ESCLANV-------SYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFrvdycgrgeLSERQQKLNQHL 243
Cdd:pfam06745 74 LEKleeEGKLAIIdastsgiGIAEVEDRFDLEELIERLREAIREIGAKRVVIDSITTLF---------YLLKPAVAREIL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 244 FKLNRLAEEFNVAVFLTNQVqsdpgasalfasADGRKPIGGHVLAHASAT-RILLRKGRGDE------RVAKLQDSPDMP 316
Cdd:pfam06745 145 RRLKRVLKGLGVTAIFTSEK------------PSGEGGIGGYGVEEFIVDgVIRLDLKEIEEervrtiEIVKMRGTPHSM 212
|
250
....*....|...
gi 6321027 317 eKECVYVIGEKGI 329
Cdd:pfam06745 213 -KRYPFEITDNGI 224
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
102-260 |
1.55e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 41.98 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 102 QLDSILGGGIMTMSITEVFGEFRCGKT----QMShtLCVTTQLP---REMGGGEGKVAYIDTEGTFR--PERIKQIAEGY 172
Cdd:pfam13481 21 PRRWLIKGLLPAGGLGLLAGAPGTGKTtlalDLA--AAVATGKPwlgGPRVPEQGKVLYVSAEGPADelRRRLRAAGADL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 173 E-------LDPESCLANVSYARAlnSEHQMELVEQLGEEL-SSGDYRLIVVDSIMAnfrvdYCGRGELSERQqkLNQHLF 244
Cdd:pfam13481 99 DlparllfLSLVESLPLFFLDRG--GPLLDADVDALEAALeEVEDPDLVVIDPLAR-----ALGGDENSNSD--VGRLVK 169
|
170
....*....|....*.
gi 6321027 245 KLNRLAEEFNVAVFLT 260
Cdd:pfam13481 170 ALDRLARRTGATVLLV 185
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
96-263 |
3.31e-04 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 41.75 E-value: 3.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 96 LSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTqmshTLcvTTQLPREMGGGEGKVAYIDTEGT-----FRPERIKQIAE 170
Cdd:cd01121 64 ISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKS----TL--LLQVAARLAQRGGKVLYVSGEESlsqikLRAERLGLGSD 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6321027 171 GYELDPESCLanvsyaralnsehqmelvEQLGEELSSGDYRLIVVDSIMANFR------------VDYCGrgelserqqk 238
Cdd:cd01121 138 NLYLLAETNL------------------EAILAEIEELKPSLVVIDSIQTVYSpeltsspgsvsqVRECA---------- 189
|
170 180
....*....|....*....|....*
gi 6321027 239 lnqhlFKLNRLAEEFNVAVFLTNQV 263
Cdd:cd01121 190 -----AELLRLAKETGIPVFLVGHV 209
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
26-74 |
3.52e-04 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 37.85 E-value: 3.52e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 6321027 26 GINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGK 74
Cdd:pfam14520 9 GIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
|
|
| |
