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Conserved domains on  [gi|6325200|ref|NP_015268|]
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mannosylinositol phosphorylceramide synthase catalytic subunit SUR1 [Saccharomyces cerevisiae S288C]

Protein Classification

glycosyltransferase family 32 protein( domain architecture ID 11467330)

glycosyltransferase family 32 protein similar to initiation-specific alpha-1,6-mannosyltransferase that is involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2)

CAZY:  GT32
EC:  2.4.-.-
PubMed:  11231017

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
55-184 7.36e-39

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 135.40  E-value: 7.36e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325200   55 IPKIIHQTYKTED-IPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYG 133
Cdd:COG3774   3 IPKIIHQTWFGDKeLPELVQRCIASWKKLNPDWEYRLWDDENFDDFIKEHGPEYLEAYYKLKKGAARADLFRLLLLYKYG 82

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 6325200  134 GVYIDLDDGCERKLDPLLAFPAFL---RKTSPLGVSNDVMGSVPRHPFFLKALK 184
Cdd:COG3774  83 GIYLDIDVECLKPLDPLLDGDDLFlgyEDPPPGIISNGFIAAEPGHPFLKKALE 136
 
Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
55-184 7.36e-39

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 135.40  E-value: 7.36e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325200   55 IPKIIHQTYKTED-IPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYG 133
Cdd:COG3774   3 IPKIIHQTWFGDKeLPELVQRCIASWKKLNPDWEYRLWDDENFDDFIKEHGPEYLEAYYKLKKGAARADLFRLLLLYKYG 82

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 6325200  134 GVYIDLDDGCERKLDPLLAFPAFL---RKTSPLGVSNDVMGSVPRHPFFLKALK 184
Cdd:COG3774  83 GIYLDIDVECLKPLDPLLDGDDLFlgyEDPPPGIISNGFIAAEPGHPFLKKALE 136
Gly_transf_sug pfam04488
Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short ...
 69-157 3.37e-29

Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases.


Pssm-ID: 398274 [Multi-domain]  Cd Length: 93  Bit Score: 108.57  E-value: 3.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325200     69 PEHWKEGRQKCLDLHPDYKYILWTDEMA----YEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYGGVYIDLDDGCE 144
Cdd:pfam04488   1 PERVMKAIESLIKLHPDYCYVVLSDDLDfaldINFLKSDTPWFLEAYSLLPLFIAKSDLLRYAILYKYGGIYLDTDVIPL 80

                          90
                  ....*....|...
gi 6325200    145 RKLDPLLAFPAFL 157
Cdd:pfam04488  81 KSLNSIGAQERFL 93
 
Name Accession Description Interval E-value
OCH1 COG3774
Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];
55-184 7.36e-39

Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442988 [Multi-domain]  Cd Length: 136  Bit Score: 135.40  E-value: 7.36e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325200   55 IPKIIHQTYKTED-IPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYG 133
Cdd:COG3774   3 IPKIIHQTWFGDKeLPELVQRCIASWKKLNPDWEYRLWDDENFDDFIKEHGPEYLEAYYKLKKGAARADLFRLLLLYKYG 82

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 6325200  134 GVYIDLDDGCERKLDPLLAFPAFL---RKTSPLGVSNDVMGSVPRHPFFLKALK 184
Cdd:COG3774  83 GIYLDIDVECLKPLDPLLDGDDLFlgyEDPPPGIISNGFIAAEPGHPFLKKALE 136
Gly_transf_sug pfam04488
Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short ...
 69-157 3.37e-29

Glycosyltransferase sugar-binding region containing DXD motif; The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases.


Pssm-ID: 398274 [Multi-domain]  Cd Length: 93  Bit Score: 108.57  E-value: 3.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6325200     69 PEHWKEGRQKCLDLHPDYKYILWTDEMA----YEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYGGVYIDLDDGCE 144
Cdd:pfam04488   1 PERVMKAIESLIKLHPDYCYVVLSDDLDfaldINFLKSDTPWFLEAYSLLPLFIAKSDLLRYAILYKYGGIYLDTDVIPL 80

                          90
                  ....*....|...
gi 6325200    145 RKLDPLLAFPAFL 157
Cdd:pfam04488  81 KSLNSIGAQERFL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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