|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
12-404 |
0e+00 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 719.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFMKPGgeNSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIYHsLGLTGIPIINVN 91
Cdd:PRK08256 1 NKVFVAGVGMTPFEKPG--ASWDYPDMAAEAGRAALADAGIDYDAVQQAYVGYVYGDSTSGQRALYE-VGMTGIPIVNVN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 92 NNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKEHM 171
Cdd:PRK08256 78 NNCSTGSTALFLARQAVRSGAADCALALGFEQMQPGALGSVWDDRPSPLERFDKALAELQGFDPAPPALRMFGGAGREHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 172 EKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQQYGLqSKA 251
Cdd:PRK08256 158 EKYGTTAETFAKIGVKARRHAANNPYAQFRDEYTLEDVLASPMIWGPLTRLQCCPPTCGAAAAIVCSEEFARKHGL-DRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 252 VEIVAQEMMTDLPSTFEEKSIIKVVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQGGTLV 331
Cdd:PRK08256 237 VEIVAQAMTTDTPSTFDGRSMIDLVGYDMTRAAAQQVYEQAGIGPEDIDVVELHDCFSANELLTYEALGLCPEGEAEKFI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 45476581 332 DRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAVVVTLYR 404
Cdd:PRK08256 317 DDGDNTYGGRWVVNPSGGLLSKGHPLGATGLAQCAELTWQLRGTAGARQVEGARLALQHNLGLGGACVVTLYQ 389
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
17-403 |
0e+00 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 594.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 17 VGVGMTKFMKPGGENSRDYPDMAKEAGQKALEDAQIPYS----AVEQACVGYVYGD---STSGQRAIYHSLGLTGIPIIN 89
Cdd:cd00826 1 AGAAMTAFGKFGGENGADANDLAHEAGAKAIAAALEPAGvaagAVEEACLGQVLGAgegQNCAQQAAMHAGGLQEAPAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 90 VNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMErgsigtkFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKE 169
Cdd:cd00826 81 MNNLCGSGLRALALAMQLIAGGDANCILAGGFEKME-------TSAENNAKEKHIDVLINKYGMRACPDAFALAGQAGAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 170 HMEKYGTKVEHFAKIGWKN---HKHSVNNTYSQFQDEYSLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILSSEEFVQ 243
Cdd:cd00826 154 AAEKDGRFKDEFAKFGVKGrkgDIHSDADEYIQFGDEASLDEIAKLRPAFDkedFLTAGNACGLNDGAAAAILMSEAEAQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 244 QYGLQSKAVEIVAQEMMTDLPSTFEEKSIIKVVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCP 323
Cdd:cd00826 234 KHGLQSKAREIQALEMITDMASTFEDKKVIKMVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGLCP 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 324 EGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAVVVTLY 403
Cdd:cd00826 314 EGQGGALVDRGDNTYGGKSIINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQGAGAGLALLCIGGGGGAAMCIES 393
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
17-403 |
1.29e-163 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 469.82 E-value: 1.29e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 17 VGVGMTKFMKPGGensRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGD---STSGQRAIYHsLGLTGIPIINVNNN 93
Cdd:cd00829 1 VGVGMTPFGRRSD---RSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGrfqSFPGALIAEY-LGLLGKPATRVEAA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 94 CSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIdkYGLSAhpitPQMFGYAGKEHMEK 173
Cdd:cd00829 77 GASGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASDLEWEGPEPP--GGLTP----PALYALAARRYMHR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 174 YGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQQYGLqsKAVE 253
Cdd:cd00829 151 YGTTREDLAKVAVKNHRNAARNPYAQFRKPITVEDVLNSRMIADPLRLLDCCPVSDGAAAVVLASEERARELTD--RPVW 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 254 IVAQEMMTDLPSTFEEKSIikvVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQGGTLVDR 333
Cdd:cd00829 229 ILGVGAASDTPSLSERDDF---LSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFCEKGEGGKLVRE 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 334 GDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAVVVTLY 403
Cdd:cd00829 306 GDTAIGGDLPVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQVPGARVGLAHNIGGTGSAAVVTI 375
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
11-404 |
1.01e-105 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 322.23 E-value: 1.01e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFmkpGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAI------YhsLGLTG 84
Cdd:PRK06064 1 MRDVAIIGVGQTKF---GELWDVSLRDLAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLFVSQEHIaaliadY--AGLAP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 85 IPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMergsigtkfsdrttpTDKHIEVLIDKYGLSAHPITPQMFG 164
Cdd:PRK06064 76 IPATRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKM---------------TDVPTPDATEAIARAGDYEWEEFFG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 ------YA--GKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAIL 236
Cdd:PRK06064 141 atfpglYAliARRYMHKYGTTEEDLALVAVKNHYNGSKNPYAQFQKEITVEQVLNSPPVADPLKLLDCSPITDGAAAVIL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 237 SSEEFVQQYglQSKAVEIVAQEMMTDLPSTFEEKSIikvVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITY 316
Cdd:PRK06064 221 ASEEKAKEY--TDTPVWIKASGQASDTIALHDRKDF---TTLDAAVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAY 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 317 EALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEA--GKRQVPGAKVALQHNL-G 393
Cdd:PRK06064 296 EDLGFAKKGEGGKLAREGQTYIGGDIPVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAekGRQQVIGAGYGLTHNVgG 375
|
410
....*....|.
gi 45476581 394 LGGAVVVTLYR 404
Cdd:PRK06064 376 TGHTAVVHILS 386
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
12-404 |
5.63e-80 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 255.54 E-value: 5.63e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFmkpGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRA--IYHSLGLTGIPIIN 89
Cdd:PRK12578 1 RRVAVIGVGNSKF---GRRDDVSVQELAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYPApiVAEYSGLTGKVPLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 90 VNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMergsigtkfSDRTTPTDKHIEVLIDKYGLSAH---PITPQMFGYA 166
Cdd:PRK12578 78 VEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKM---------TEVDTSTSLAIGGRGGNYQWEYHfygTTFPTYYALY 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 167 GKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQQYG 246
Cdd:PRK12578 149 ATRHMAVYGTTEEQMALVSVKAHKYGAMNPKAHFQKPVTVEEVLKSRAISWPIKLLDSCPISDGSATAIFASEEKVKELK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 247 LQSkAVEIVAQEMMTDLPSTFEEksiIKVVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQ 326
Cdd:PRK12578 229 IDS-PVWITGIGYANDYAYVARR---GEWVGFKATQLAARQAYNMAKVTPNDIEVATVHDAFTIAEIMGYEDLGFTEKGK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 327 GGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAK-VALQHNLGLGG--AVVVTLY 403
Cdd:PRK12578 305 GGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEAGKLQQPLKKyIGLVHNVGGTGhfAYVMILR 384
|
.
gi 45476581 404 R 404
Cdd:PRK12578 385 R 385
|
|
| PRK06059 |
PRK06059 |
lipid-transfer protein; Provisional |
10-401 |
1.03e-72 |
|
lipid-transfer protein; Provisional
Pssm-ID: 180373 [Multi-domain] Cd Length: 399 Bit Score: 237.35 E-value: 1.03e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 10 RLRRVFVVGVGMtkfmKPGGENSRDYPDMAKEAGQKALEDAQIPY---------SAVEQACVGYVYGdSTSGQraiyhSL 80
Cdd:PRK06059 2 MPEPVYILGAGM----HPWGKWGRDFVEYGVVAARAALADAGLDWrdvqlvvgaDTIRNGYPGFVAG-ATFAQ-----AL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 81 GLTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDkhievlidkyGLSAHPI-- 158
Cdd:PRK06059 72 GWNGAPVSSSYAACASGSQALQSARAQILAGLCDVALVVGADTTPKGFFAPVGGERPDDPD----------WLRFHLIga 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 159 -TPQMFGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILS 237
Cdd:PRK06059 142 tNPVYFALLARRRMDLYGATVEDFAQVKVKNARHGLLNPNARYRKEVTVEDVLASPVVSDPLRLLDICATSDGAAALIVA 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 238 SEEFVQQYGLQSK-AVEIVAQEMMT--------DLPsTFEEKSIIKVVGYDMS--KEAARRCYEKSGLTPNDVDVIELHD 306
Cdd:PRK06059 222 SKSFARRHLGSVAgVPSVRAISTVTprypqhlpELP-DIATDSTAAVPAPERVfkDQILDAAYAEAGIGPEDLSLAEVYD 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 307 CFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKV 386
Cdd:PRK06059 301 LSTALELDWYEHLGLCPKGEAEALLRSGATTLGGRIPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQAGGRQVEGARV 380
|
410
....*....|....*...
gi 45476581 387 ALQHNLGL---GGAVVVT 401
Cdd:PRK06059 381 GITANQGLfghGSSVIVA 398
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
12-393 |
1.51e-65 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 218.36 E-value: 1.51e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFmkpgGEN-SRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIYHS--LGLTGIPII 88
Cdd:PRK06157 7 DKVAILGMGCTKF----GERwDAGAEDLMVEAFLEALADAGIEPKDIDAAWFGTHYDEIGSGKSGTPLSraLRLPNIPVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 89 NVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEK-MERGSIGTKFSDRTTPTDKHIEvlidkyGLSAhpitPQMFGYAG 167
Cdd:PRK06157 83 RVENFCATGSEAFRGAVYAVASGAYDIALALGVEKlKDTGYGGLPVANPGTLADMTMP------NVTA----PGNFAQLA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 168 KEHMEKYGTKVEHF----AKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQ 243
Cdd:PRK06157 153 SAYAAKYGVSREDLkramAHVSVKSHANGARNPKAHLRKAVTEEQVLKAPMIAGPLGLFDCCGVSDGAAAAIVTTPEIAR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 244 QYG----LQSKAVEIVA---QEMMTDlpstfeeksiikvvGYDMS-----KEAARRCYEKSGLT-P-NDVDVIELHDCFS 309
Cdd:PRK06157 233 ALGkkdpVYVKALQLAVsngWELQYN--------------GWDGSyfpttRIAARKAYREAGITdPrEELSMAEVHDCFS 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 310 VNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQ 389
Cdd:PRK06157 299 ITELVTMEDLGLSERGQAWRDVLDGFFDADGGLPCQIDGGLKCFGHPIGASGLRMLYEMYLQLLGRAGERQLKNPRLALT 378
|
....
gi 45476581 390 HNLG 393
Cdd:PRK06157 379 HNLG 382
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
13-398 |
1.29e-62 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 210.19 E-value: 1.29e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 13 RVFVVGVGMTKFMKPGGEnsrDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYG----DSTSGQRAIYHSLGLTGIPII 88
Cdd:PRK07516 3 TASIVGWAHTPFGKLDAE---TLESLIVRVAREALAHAGIAAGDVDGIFLGHFNAgfspQDFPASLVLQADPALRFKPAT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 89 NVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERgsigtkfsdrtTPTDKHIEVLID-KYGLSAHPIT---PQMFG 164
Cdd:PRK07516 80 RVENACATGSAAVYAALDAIEAGRARIVLVVGAEKMTA-----------TPTAEVGDILLGaSYLKEEGDTPggfAGVFG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 YAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLE---EVMKSKP-VFDFLTILQCCPTSDGAAAAILSSEE 240
Cdd:PRK07516 149 RIAQAYFQRYGDQSDALAMIAAKNHANGVANPYAQMRKDLGFEfcrTVSEKNPlVAGPLRRTDCSLVSDGAAALVLADAE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 241 FVQQYglqSKAVEIVAQEMMTD-LPstfeeksiikvvgydMSK------EAARRC----YEKSGLTPNDVDVIELHDCFS 309
Cdd:PRK07516 229 TARAL---QRAVRFRARAHVNDfLP---------------LSRrdplafEGPRRAwqraLAQAGVTLDDLSFVETHDCFT 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 310 VNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQ 389
Cdd:PRK07516 291 IAELIEYEAMGLAPPGQGARAIREGWTAKDGKLPVNPSGGLKAKGHPIGATGVSMHVLAAMQLTGEAGGMQIPGAKLAGV 370
|
....*....
gi 45476581 390 HNLGlGGAV 398
Cdd:PRK07516 371 FNMG-GAAV 378
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
36-401 |
1.86e-61 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 203.06 E-value: 1.86e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVYGD---STSGQRAIYHsLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGL 112
Cdd:cd00327 8 SELGFEAAEQAIADAGLSKGPIVGVIVGTTGGSgefSGAAGQLAYH-LGISGGPAYSVNQACATGLTALALAVQQVQNGK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 113 ANCVLALGFEKmergsigtkfsdrttptdkhievlidkyglsahpitpqmfgyagkehmekygtkvehfakigwknhkhs 192
Cdd:cd00327 87 ADIVLAGGSEE--------------------------------------------------------------------- 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 193 vnntysqfqdeysleevmkskpvfdfltilqcCPTSDGAAAAILSSEEFVQQYGlqskaveIVAQEMMTDLPSTFEEKSI 272
Cdd:cd00327 98 --------------------------------FVFGDGAAAAVVESEEHALRRG-------AHPQAEIVSTAATFDGASM 138
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 273 IKVVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQGGtlvdrgdntyggkwvINPSGGLIS 352
Cdd:cd00327 139 VPAVSGEGLARAARKALEGAGLTPSDIDYVEAHGTGTPIGDAVELALGLDPDGVRS---------------PAVSATLIM 203
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 45476581 353 KGHPLGATGLAQCAELCWQLRGEAGK--RQVPGAKVALQHNLGLGGAVVVT 401
Cdd:cd00327 204 TGHPLGAAGLAILDELLLMLEHEFIPptPREPRTVLLLGFGLGGTNAAVVL 254
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
6-402 |
1.96e-59 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 203.22 E-value: 1.96e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 6 LKSPRLRR-VFVVGVGMTKFMKPGGENsrDYPDMAKEAGQKALEDAQIPYSAVEQACVGYV---YGDSTSGQRAIYHSLG 81
Cdd:PRK06365 9 LKMKKKSRdVYMVAAGVTKFDKASPYM--DFRERVKKAFDYAMNDAGLTLADIDGSVASYFsdhFQRQLLAGIMVQDYLG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 82 LTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERgsigtkfsdrtTPTDKHIEVLidkyGLSA-----H 156
Cdd:PRK06365 87 LVPKPSKRIEGGGATGGLAFQAGYEEIASGRMDCVAVYGFETMSH-----------VNTWKGNEFI----ALASdtnfdY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 157 PITPQMFGY---AGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAA 233
Cdd:PRK06365 152 PLGGFYTGYyamMAVRHMYEFGTTVEQLAKVSVKNHGNAIHNPFAQSPMKITVEDVRKSPMVSYPLTRLDVCAMSDGAAC 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 234 AILSSEEfvQQYGLQSKAVEIVAQEMMTD--------------LPStfEEKSIIK------VVGYDMSKEAARRCYEKSG 293
Cdd:PRK06365 232 AILASED--KAFEITDKPVLIKAIGTGSDtlrladrpfgevplLPN--ESPDDYKdlrypgVHSFRAGRMAAKEAYEMAG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 294 LTP--NDVDVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQ 371
Cdd:PRK06365 308 ITDplNDLDLIELHDAYTSSEIQTYEDLGLCKYGEGGQFIESGKPELPGKLPVNPSGGLLAAGHAVGATGIMQAVFMFWQ 387
|
410 420 430
....*....|....*....|....*....|....*...
gi 45476581 372 LRGEAGKR------QVPGAKVALQH-NLGLGGAVVVTL 402
Cdd:PRK06365 388 LQGRIKKHfhddylQVKNAKRGLIHsHAGTGTYVTVTI 425
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
14-402 |
1.63e-47 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 170.25 E-value: 1.63e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 14 VFVVGVGMTKFMKPGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQR------AIYHSlGLTGIPI 87
Cdd:PRK06289 5 VWVLGGYQSDFARNWTKEGRDFADLTREVVDGTLAAAGVDADDIEVVHVGNFFGELFAGQGhlgampATVHP-ALWGVPA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 88 INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMergsigtkfsdRTTPTDKHIEVL-----IDKYGLSAHPITPQM 162
Cdd:PRK06289 84 SRHEAACASGSVATLAAMADLRAGRYDVALVVGVELM-----------KTVPGDVAAEHLgaaawTGHEGQDARFPWPSM 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 163 FGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQ-----FQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILS 237
Cdd:PRK06289 153 FARVADEYDRRYGLDEEHLRAIAEINFANARRNPNAQtrgwaFPDEATNDDDATNPVVEGRLRRQDCSQVTDGGAGVVLA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 238 SEEFVQQY-------------------GLQSKAVEIVAQEMMtdLPSTfeeksiikvvgydmsKEAARRCYEKSGLTPND 298
Cdd:PRK06289 233 SDAYLRDYadarpiprikgwghrtaplGLEQKLDRSAGDPYV--LPHV---------------RQAVLDAYRRAGVGLDD 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 299 VDVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGK 378
Cdd:PRK06289 296 LDGFEVHDCFTPSEYLAIDHIGLTGPGESWKAIENGEIAIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVTGTAGD 375
|
410 420
....*....|....*....|....
gi 45476581 379 RQVPGAKVALQHNLGLGGAVVVTL 402
Cdd:PRK06289 376 YQVEGAKTFGTLNIGGSTTTTVSF 399
|
|
| PRK08313 |
PRK08313 |
thiolase domain-containing protein; |
12-397 |
2.95e-47 |
|
thiolase domain-containing protein;
Pssm-ID: 181378 [Multi-domain] Cd Length: 386 Bit Score: 169.14 E-value: 2.95e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFMKPGGENSrdYPDMAKEAGQKALEDAQIPYSAVEQACVGY---VYGDSTSGQRAIYHSLGLTGIPII 88
Cdd:PRK08313 3 RLAAVLGTGQTKYVAKRQDVS--MAGLVREAIDRALADAGLTWDDIDAVVVGKapdFFEGVMMPELFLADALGATGKPLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 89 NVNNNCSTG-STALFMAHqLIQGGLANCVLALGFEKMERGSigtkfsdrttptdkhievliDKYGLSAH-PITPQMFGYA 166
Cdd:PRK08313 81 RVHTAGSVGgSTAVVAAS-LVQSGVYRRVLAVAWEKQSESN--------------------AMWALSIPvPFTKPVGAGA 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 167 G-------KEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQF-QDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSS 238
Cdd:PRK08313 140 GgyfaphvRAYIRRSGAPEHIGAMVAVKDRLNGAKNPYAHLhQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVIGD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 239 EEFVQQYGLQSKAVeIVAQEMMTDlPSTFEEKSiikVVGYDMSKEAARRCYEKSGLT-P-NDVDVIELHDCFSVNELITY 316
Cdd:PRK08313 220 EEAADAAAGRPVAW-IHGTAMRTE-PLAFAGRD---QVNPQAGRDAAAALWKAAGITdPrDEIDVAEIYVPFSWFEPMWL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 317 EALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISkGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGlGG 396
Cdd:PRK08313 295 ENLGFAPEGEGWKLTEAGETAIGGRLPVNPSGGVLS-SNPIGASGMIRFAEAALQVMGKAGEHQVDGARKALGHAYG-GG 372
|
.
gi 45476581 397 A 397
Cdd:PRK08313 373 S 373
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
37-396 |
1.25e-39 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 148.25 E-value: 1.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALEDAQIPYSAVEQACVGYVYgDSTSGQRAIYHslglTGIPIINVNNNCSTGSTalFMAH-----QLIQGG 111
Cdd:PRK06158 30 ELLAQAAHRALADAGLTMADVDGLFTASPD-DALWGLSVAEY----LGIRPRFVDGTMIGGSS--FLAHllpaaLALEAG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVL-ALGfekMERGSIGTKFSDRTTPTdkhievlidkygLSAHPITPQM----FGYAGKEHMEKYGTKVEHFAKIGW 186
Cdd:PRK06158 103 LCDVALiCYG---SNQRSAGGKLRSMLDPQ------------PYEAPYKPVNpvsaYALAAARHMHQYGTTREQLAEVAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 187 KNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQqyGLQSKAVEIVAQEM------- 259
Cdd:PRK06158 168 AARQWAQLNPEAFMRDPLTIDDVLAARMVSDPLSVRDCCLVTDGAGAVVMVRADRAR--DLPRPPVYVLGAAAatwhrqi 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 260 --MTDLPSTfeeksiikvvgydMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNT 337
Cdd:PRK06158 246 ssMPDLTVT-------------AAAESGPRAFAMAGLTPADIDVVELYDAFTINTILFLEDLGFCAKGEGGAFVEGGRIA 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 45476581 338 YGGKWVINPSGGLISKGHPlGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHnlGLGG 396
Cdd:PRK06158 313 PGGRLPVNTNGGGLSCVHP-GMYGLFLLIEAVRQLRGEAGERQVAGAEVALAH--GNGG 368
|
|
| PRK06065 |
PRK06065 |
thiolase domain-containing protein; |
12-382 |
9.66e-39 |
|
thiolase domain-containing protein;
Pssm-ID: 180379 [Multi-domain] Cd Length: 392 Bit Score: 146.12 E-value: 9.66e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFMKPGGENSRDypdMAKEAGQKALEDAQIPYSAVEQACVGYVyGDSTSG--QRAIYHSLGLTGI--PI 87
Cdd:PRK06065 9 KRVAVIGAGLTLFRRRLLETPQE---LAWEAASKALDEAGLELKDIDCVVIGSA-PDAFDGvhMKGEYLSHGSGGIrkPV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 88 INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMErgsigtkfSDRTTPTD--KHI-EVLIDKyglsahPITPQM-- 162
Cdd:PRK06065 85 SRVYVGGATGVMTAIAGWYHVASGLCQKVLAVAEEKMS--------PARPHPQAvfRYIwDPILEK------PLNPNLiw 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 163 -FGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEF 241
Cdd:PRK06065 151 iFAMEMHRYMATYGIKKEEIALVSVKNKRNALNNPYAQLGSKITVEDVLKSEVLVWPVQLLDVSPVSDGAAAIVLASEDL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 242 VQQYglqskaveivaqemmTDLPSTfeeksiIKVVGYDMS---------------KEAARRCYEKSGLT-PN-DVDVIEL 304
Cdd:PRK06065 231 ARRY---------------TDTPVW------VEGVGWTLDntewpnrdlaypryvEFAARMAYKMAGIErPRkEIDVAEP 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45476581 305 HDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVP 382
Cdd:PRK06065 290 YDPFDYKELHHLEGLQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGTAGKMQVK 367
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
10-396 |
4.19e-34 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 134.25 E-value: 4.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 10 RLRRVFVVGVGMTKFMKPGGEN--SRDYPDMAK-----------EAGQKALEDAQIPYSA--VEQACVGYVYGDSTSGQ- 73
Cdd:PTZ00455 10 AAKRVFVVGGHITPFVGKGSPLfiDKKHPDFGKkenktleellaTAIQGTLENTGLDGKAalVDKVVVGNFLGELFSSQg 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 74 ---RAIYHSLGLTGI-------PIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGS--IGTKFSDRTTptD 141
Cdd:PTZ00455 90 hlgPAAVGSLGQSGAsnallykPAMRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEVQTTVSarVGGDYLARAA--D 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 142 KHIEVLIDKYGLsahpitPQMFGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQ-FQDEYSLEEVMK---SKPVF- 216
Cdd:PTZ00455 168 YRRQRKLDDFTF------PCLFAKRMKYIQEHGHFTMEDTARVAAKAYANGNKNPLAHmHTRKLSLEFCTGasdKNPKFl 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 217 ------DFLTILQCCPTSDGAAAAILSSEEFVQQYGLQ---SKAVEIVAQE-----MMTDLPSTfeeksiikvvgYDM-- 280
Cdd:PTZ00455 242 gnetykPFLRMTDCSQVSDGGAGLVLASEEGLQKMGLSpndSRLVEIKSLAcasgnLYEDPPDA-----------TRMft 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 281 SKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 360
Cdd:PTZ00455 311 SRAAAQKALSMAGVKPSDLQVAEVHDCFTIAELLMYEALGIAEYGHAKDLIRNGATALEGRIPVNTGGGLLSFGHPVGAT 390
|
410 420 430
....*....|....*....|....*....|....*.
gi 45476581 361 GLAQCAELCWQLRGEAGKRQVPGAkVALQHNLGLGG 396
Cdd:PTZ00455 391 GVKQIMEVYRQMKGQCGEYQMKNI-PALGATLNMGG 425
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
36-400 |
1.67e-32 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 128.37 E-value: 1.67e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVYGdSTSGQ---RAIYHSLGL-TGIPIINVNNNCSTGSTALFMAHQLIQGG 111
Cdd:cd00751 23 DDLGAAVIKALLERAGLDPEEVDDVIMGNVLQ-AGEGQnpaRQAALLAGLpESVPATTVNRVCGSGLQAVALAAQSIAAG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAgkEHM-EKYG-TKVE---------- 179
Cdd:cd00751 102 EADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGMLDDGLTDPFTGLSMGITA--ENVaEKYGiSREEqdefalrshq 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 180 ---------HFA------KIGWKNHKHSVNntysqfQDEY-----SLEEVMKSKPVFD---FLTILQCCPTSDGAAAAIL 236
Cdd:cd00751 180 raaaaqeagRFKdeivpvEVPGRKGPVVVD------RDEGprpdtTLEKLAKLKPAFKkdgTVTAGNASGINDGAAAVLL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 237 SSEEFVQQYGLQSKAVeIVAQEmmtdlpstfeeksiikVVGYD---MSK---EAARRCYEKSGLTPNDVDVIELHDCFSV 310
Cdd:cd00751 254 MSEEKAKELGLKPLAR-IVGYA----------------VAGVDpaiMGIgpvPAIPKALKRAGLTLDDIDLIEINEAFAA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 311 NELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVpgakVALQH 390
Cdd:cd00751 317 QALACLKELGLDPE------------------KVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGL----ATMCI 374
|
410
....*....|
gi 45476581 391 NLGLGGAVVV 400
Cdd:cd00751 375 GGGQGAAMVI 384
|
|
| SCP2 |
pfam02036 |
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the ... |
452-538 |
4.39e-32 |
|
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the SCP2 protein as well as the C terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.
Pssm-ID: 460423 [Multi-domain] Cd Length: 100 Bit Score: 118.90 E-value: 4.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 452 VKKIGG-IFAFKVKDGPGgkeaTWVVDVKNGKGSVLPNSDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGNMG 530
Cdd:pfam02036 15 LKKLNGkVIRFDLTDLGL----SLTLDLKDGGGRVLAGDEGKADVTLSASDSDLLALATGKLNPQKAFMQGKLKIEGDME 90
|
....*...
gi 45476581 531 LAMKLQNL 538
Cdd:pfam02036 91 LAQKLEGL 98
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
11-400 |
1.14e-31 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 126.02 E-value: 1.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFMKPGGENSrdYPDMAKEAGQKALEDAQI--PYSAVeqacvgyvygDS-TSGQRAIYHSLGLT---- 83
Cdd:PRK06066 3 LNRVAIVGIGWYGFRPTTPEVS--FREMMFEAASRAYKDAGNinPRRDV----------DSfISCQEDFWEGIAIAdefa 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 84 -----GI--PIINVnnncsTGSTALFMAH--QLIQGGLANCVLALGFEKmergsigtkfsdrttPTDkhIEVLIDKYGLS 154
Cdd:PRK06066 71 pdqigGAmrPTMTV-----AGDGLQGLAHavMHINSGLANVVVVEAHSK---------------PSD--ILTFSDVVKFA 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 155 AHPI------TPQMFGYAGKE---HMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCC 225
Cdd:PRK06066 129 MDPIyvrpigPPNPHFIAGLDavkFMSRKGITREDLALVVEKNKKAGLSNPRASYASNISLEDVLSSEYVVYPLTELDIA 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 226 PTSDGAAAAILSSEEFVQQYglqskaveivaqemmTDLPStfeeksIIKVVGY--DMS-------------KEAARRCYE 290
Cdd:PRK06066 209 PFVDGAIVVVLASEEVAKKL---------------TDDPV------WIKGIGWstESSnletaelgkanymRIAADMAYK 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 291 KSGLTP--NDVDVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAEL 368
Cdd:PRK06066 268 MAGIESprKEVDAAEVDDRYSYKELQHIEALRLSEEPEKDSLLREGNFDPQGELPVNPSGGHLAKGVPLEASGLSLLLDA 347
|
410 420 430
....*....|....*....|....*....|....*.
gi 45476581 369 CWQLRGEAGKRQvPGAKVALQHNL----GLGGAVVV 400
Cdd:PRK06066 348 VEYLRGEAGARQ-GKAERAVVASWrgipTLTGSVVV 382
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
22-400 |
2.85e-29 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 119.25 E-value: 2.85e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 22 TKFMKPGGENSRDYP-DMAKEAGQKALEDAQIPYSAVEQACVGYVygDSTSGQR------AIYHSLGLTgIPIINVNNNC 94
Cdd:TIGR01930 7 TPIGKFGGSLKDVSAeDLGAAVIKELLERNPLDPELIDDVIFGNV--LQAGEQQniarqaALLAGLPES-VPAYTVNRQC 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 95 STGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKEHMEKY 174
Cdd:TIGR01930 84 ASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSLRWGVKPGNAELEDARLKDLTDANTGLPMGVTAENLAKKY 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 175 G-TKVE--HFA----KIGWKNHK-------------HSVNNTYSQFQDE-----YSLEEVMKSKPVFD---FLTILQCCP 226
Cdd:TIGR01930 164 GiSREEqdEYAlrshQRAAKAWEeglfkdeivpvtvKGRKGPVTVSSDEgirpnTTLEKLAKLKPAFDpdgTVTAGNSSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 227 TSDGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFeeksiikvvGYdMSKEAARRCYEKSGLTPNDVDVIELHD 306
Cdd:TIGR01930 244 LNDGAAALLLMSEEKAKELGLTPLA-RIVSFAVAGVDPEIM---------GL-GPVPAIPKALKKAGLSISDIDLFEINE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 307 CFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVpgakV 386
Cdd:TIGR01930 313 AFAAQVLACIKELGLDLE------------------KVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGL----A 370
|
410
....*....|....
gi 45476581 387 ALQHNLGLGGAVVV 400
Cdd:TIGR01930 371 TMCIGGGQGAAVIL 384
|
|
| PRK08142 |
PRK08142 |
thiolase domain-containing protein; |
156-397 |
2.32e-27 |
|
thiolase domain-containing protein;
Pssm-ID: 236164 [Multi-domain] Cd Length: 388 Bit Score: 113.64 E-value: 2.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 156 HPITPQMFGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAI 235
Cdd:PRK08142 139 GPTTHNLYAMCAMRHMHEYGTTSEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMIADPLHRLDCCVVTDGGGALV 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 236 LSSEEfvqqyglqskaveiVAQEMmtdlpstfeEKSIIKVVGY------------DMSKEAAR----RCYEKSGLTPNDV 299
Cdd:PRK08142 219 VVRPE--------------IARSL---------KRPLVKVLGAgeaikgqmggkvDLTYSGAAwsgpAAFAEAGVTPADI 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 300 DVIELHDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYG-GKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAG- 377
Cdd:PRK08142 276 KYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGvGKLPFNTDGGGLCNNHPANRGGMTKVIEAVRQLRGEAHp 355
|
250 260
....*....|....*....|
gi 45476581 378 KRQVPGAKVALQHnlGLGGA 397
Cdd:PRK08142 356 AVQVPNCDLALAH--GTGGL 373
|
|
| PRK07855 |
PRK07855 |
lipid-transfer protein; Provisional |
16-384 |
2.81e-26 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181147 [Multi-domain] Cd Length: 386 Bit Score: 110.45 E-value: 2.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 16 VVGVGMTKFMKPGGENSRDypdMAKEAGQKALEDAQIPYSAVEqacvGYV-YGDSTSGQRAIYHSLG---LTGIPIINVN 91
Cdd:PRK07855 8 IVGIGATEFSKNSGRSELR---LACEAVLAALDDAGLAPSDVD----GLVtFTMDTNPEIAVARALGigeLKFFSRIHYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 92 NNCSTGSTA-LFMAhqlIQGGLANCVLAlgFEKMERGSiGTKFSDRTTPTDKHIEVLIDKYGLSAhP---ITP-QMFGYA 166
Cdd:PRK07855 81 GGAACATVQqAAMA---VATGVADVVVC--YRAFNERS-GMRFGQGQTGLAENPTSTGVDYGWSY-PhglLTPaAWVAML 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 167 GKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDE-YSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQQy 245
Cdd:PRK07855 154 ARRYMHEYGATSEDFGRVAVADRKHAATNPKAWFYGRpITLEDHQNSRWIAEPLRLLDCCQESDGAVALVVTSAERARD- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 246 gLQSKAVEIVA--------QEMMT----DLPSTFEEKSIikvvgydmskeAARRCYEKSGLTPNDVDVIELHDCFSVNEL 313
Cdd:PRK07855 233 -LKQRPAVIKAaaqgsgadQYMMTsyyrDDITGLPEMGL-----------VARQLWAQSGLGPADIDTAILYDHFTPFVL 300
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45476581 314 ITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLaqcAELCWQLRGEAgKRQVPGA 384
Cdd:PRK07855 301 MQLEELGFCGRGEAKDFIADGALELGGRLPINTHGGQLGEAYIHGMNGI---AEAVRQLRGTS-VNQVPGV 367
|
|
| SCP2 |
COG3255 |
Putative sterol carrier protein, contains SCP2 domain [Lipid transport and metabolism]; |
453-538 |
1.66e-24 |
|
Putative sterol carrier protein, contains SCP2 domain [Lipid transport and metabolism];
Pssm-ID: 442486 [Multi-domain] Cd Length: 104 Bit Score: 97.67 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 453 KKIGGIFAFKVKDGPGGkeaTWVVDVKNGKGSVLPNSDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGNMGLA 532
Cdd:COG3255 18 AGWDGVVQFVITGEGGG---AYYLVIDDGKCTVSEGDDDDADVTLTASYEDWKKLLTGELDPMTAFMTGKLKVEGDMGLA 94
|
....*.
gi 45476581 533 MKLQNL 538
Cdd:COG3255 95 MKLMSL 100
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
12-400 |
1.31e-22 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 99.76 E-value: 1.31e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMTKFMKPGGE-NSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVygdSTSGQ-----RAIYHSLGL-TG 84
Cdd:COG0183 2 REVVIVDAVRTPFGRFGGAlADVRADDLGAAVIKALLERAGLDPEAVDDVILGCV---LQAGQgqnpaRQAALLAGLpES 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 85 IPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFG 164
Cdd:COG0183 79 VPAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMNAKLVDPMINPGLTDPYTGLSMGE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 YAgkEHM-EKYG-TKVE-------------------HFAK------IGWKNHKHSVNntysqfQDEY-----SLEEVMKS 212
Cdd:COG0183 159 TA--ENVaERYGiSREEqdafalrshqraaaaiaagRFDDeivpveVPDRKGEVVVD------RDEGprpdtTLEKLAKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 213 KPVFD---FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAvEIVAQ-------EMMTDLPStfeeksiikvvgydmsk 282
Cdd:COG0183 231 KPAFKkdgTVTAGNASGINDGAAALLLMSEEAAKELGLKPLA-RIVAYavagvdpEIMGIGPV----------------- 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 283 EAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGL 362
Cdd:COG0183 293 PATRKALARAGLTLDDIDLIEINEAFAAQVLAVLRELGLDPD------------------KVNVNGGAIALGHPLGASGA 354
|
410 420 430
....*....|....*....|....*....|....*...
gi 45476581 363 AQCAELCWQLRGEAGKRQVpgakVALQHNLGLGGAVVV 400
Cdd:COG0183 355 RILVTLLHELERRGGRYGL----ATMCIGGGQGIALII 388
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
14-240 |
2.29e-18 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 85.05 E-value: 2.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 14 VFVVGVGMTKFMKPGGeNSRDYP--DMAKEAGQKALEDAQIPYSAVEQACVGYVyGDSTSGQ---RAIYHSLGLT-GIPI 87
Cdd:pfam00108 1 VVIVSAARTPFGSFGG-SLKDVSavELGAEAIKAALERAGVDPEDVDEVIVGNV-LQAGEGQnpaRQAALKAGIPdSAPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 88 INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDR---TTPTDKHIEVLIdKYGLSAHPITPQMfG 164
Cdd:pfam00108 79 VTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARsglKHGDEKKHDLLI-PDGLTDAFNGYHM-G 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 YAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQ-FQDE------------------------YSLEEVMKSKPVFD-- 217
Cdd:pfam00108 157 LTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAGkFKDEivpvtvkgrkgkptvdkdegirppTTAEPLAKLKPAFDke 236
|
250 260
....*....|....*....|....
gi 45476581 218 -FLTILQCCPTSDGAAAAILSSEE 240
Cdd:pfam00108 237 gTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
85-400 |
3.69e-18 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 86.70 E-value: 3.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 85 IPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTkfsdrttptDKHIEV----LID-KY-------- 151
Cdd:PRK06445 86 IPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGD---------NPHIEPnpklLTDpKYieydlttg 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 152 ---GLSAHpitpQMFGYAG--KEHMEKYGTKVEHFA----KIGW-----------KNHKHSVNNTYSQFQDEYSLEEVMK 211
Cdd:PRK06445 157 yvmGLTAE----KLAEEAGikREEMDRWSLRSHQLAakaiQEGYfkdeilpieveVEGKKKVVDVDQSVRPDTSLEKLAK 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 212 SKPVFD---FLTILQCCPTSDGAAAAILSSEEFVQQYGLQ--SKAVEI----VAQEMMTDLPSTfeeksiikvvgydmsk 282
Cdd:PRK06445 233 LPPAFKpdgVITAGNSSPLNSGASYVLLMSKKAVKKYGLKpmAKIRSFgfagVPPAIMGKGPVP---------------- 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 283 eAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGL 362
Cdd:PRK06445 297 -ASKKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLDPE------------------TVNIKGGAIAIGHPLGATGA 357
|
330 340 350
....*....|....*....|....*....|....*...
gi 45476581 363 AQCAELCWQLRGEAGKRQVPGAKVAlqhnLGLGGAVVV 400
Cdd:PRK06445 358 RIVGTLARQLQIKGKDYGVATLCVG----GGQGGAVVL 391
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
11-402 |
3.65e-17 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 83.52 E-value: 3.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFMKPGGENSR-DYPDMAKEAGQKALEDAQIPYSAVEQACVGYVY----GDSTSGQrAIYHSLGLTGI 85
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGRSFSKiKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIqagvGQNPAGQ-AAYHAGLPFGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 86 PIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPtdKHIevLIDKYGLSAHPITPQMFGY 165
Cdd:PRK06366 80 TKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLPSDLRWGP--KHL--LHKNYKIDDAMLVDGLIDA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 166 AGKEHM--------EKYGTKVEHFAKIGWKNHKHSVNNTYS-QFQDEY---------------SLEEVMKSKPVFD---F 218
Cdd:PRK06366 156 FYFEHMgvsaertaRKYGITREMADEYSVQSYERAIRATESgEFRNEIvpfndldrdegirktTMEDLAKLPPAFDkngI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 219 LTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPND 298
Cdd:PRK06366 236 LTAGNSAQLSDGGSALVMASEKAINEYGLKPIA-RITGYESASLDPLDFVEAPI----------PATRKLLEKQNKSIDY 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 299 VDVIELHDCFSVNELITYEALGLcpegqggtlvdrgDNTYggkwvINPSGGLISKGHPLGATGlaqcAELCWQLRGEAGK 378
Cdd:PRK06366 305 YDLVEHNEAFSIASIIVRDQLKI-------------DNER-----FNVNGGAVAIGHPIGNSG----SRIIVTLINALKT 362
|
410 420
....*....|....*....|....
gi 45476581 379 RQVPGAKVALQHnlGLGGAVVVTL 402
Cdd:PRK06366 363 RHMKTGLATLCH--GGGGAHTLTL 384
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
37-378 |
6.74e-17 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 82.74 E-value: 6.74e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALedAQIP---YSAVEQACVGYVYGDSTSGQRAIYHSLGLTGIPI----INVNNNCSTGSTALFMAHQLIQ 109
Cdd:PRK09052 33 DLLAHVLRSAV--AQVPgldPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLPNsvggVTVNRFCASGLQAVAMAADRIR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 110 GGLANCVLALGFEKMERGSI-GTKFSDRTTPTDKHIEVLI----------------------DKYGLSAH--PITPQMFG 164
Cdd:PRK09052 111 VGEADVMIAAGVESMSMVPMmGNKPSMSPAIFARDENVGIaygmgltaekvaeqwkvsredqDAFALESHqkAIAAQQAG 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 YAGKEhMEKYgTKVEHFAKIgwkNHKHSVNNTYSQFQDE-----YSLEEVMKSKPVFDF---LTILQCCPTSDGAAAAIL 236
Cdd:PRK09052 191 EFKDE-ITPY-EITERFPDL---ATGEVDVKTRTVDLDEgpradTSLEGLAKLKPVFANkgsVTAGNSSQTSDGAGAVIL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 237 SSEEFVQQYGLQ------SKAVEIVAQEMMTDLPstfeeksiikvvgydmsKEAARRCYEKSGLTPNDVDVIELHDCFSV 310
Cdd:PRK09052 266 VSEKALKQFNLTplarfvSFAVAGVPPEIMGIGP-----------------IEAIPAALKQAGLKQDDLDWIELNEAFAA 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45476581 311 NELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGK 378
Cdd:PRK09052 329 QSLAVIRDLGLDPS------------------KVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLK 378
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
11-361 |
5.88e-15 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 76.67 E-value: 5.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFMKPGGENSrdyPDMAKEAG----QKALEDAQIPYSAVEQACVGYVYgDSTSGQ---RAIYHSLGLT 83
Cdd:PRK08235 1 MSKTVIVSAARTPFGKFGGSLK---DVKATELGgiaiKEALERANVSAEDVEEVIMGTVL-QGGQGQipsRQAARAAGIP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 84 -GIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKM-------ERGSIGTKFSDRT------------TPTDKH 143
Cdd:PRK08235 77 wEVQTETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMsnapyilPGARWGYRMGDNEvidlmvadgltcAFSGVH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 144 IEV----LIDKYGLSAHpitpQMFGYAGKEHME-----KYGTKVEHFAKIGWKNHKhsvNNTYSQFQDE-----YSLEEV 209
Cdd:PRK08235 157 MGVyggeVAKELGISRE----AQDEWAYRSHQRavsahEEGRFEEEIVPVTIPQRK---GDPIVVAKDEaprkdTTIEKL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 210 MKSKPVFD---FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVeIVAQEMMTDLPSTFEeksiiKVVGYdmskeAAR 286
Cdd:PRK08235 230 AKLKPVFDktgTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLAT-ILAHTAIAVEAKDFP-----RTPGY-----AIN 298
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45476581 287 RCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATG 361
Cdd:PRK08235 299 ALLEKTGKTVEDIDLFEINEAFAAVALASTEIAGIDPE------------------KVNVNGGAVALGHPIGASG 355
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
36-361 |
3.52e-14 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 74.42 E-value: 3.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVYGdSTSGQRAIYHSLGLTGIPI----INVNNNCSTGSTALFMAHQLIQGG 111
Cdd:PRK05790 27 VELGAIVIKAALERAGVPPEQVDEVIMGQVLQ-AGAGQNPARQAALKAGLPVevpaLTINKVCGSGLKAVALAAQAIRAG 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVLALGFEKMER------GS-IGTKFSDrTTPTDKHI-EVLIDKYglsahpiTPQMFGYAGKEHMEKYG-TKVE--H 180
Cdd:PRK05790 106 DADIVVAGGQESMSQaphvlpGSrWGQKMGD-VELVDTMIhDGLTDAF-------NGYHMGITAENLAEQYGiTREEqdE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 181 F-------AKIGWKNHKHS---VNNTYSQ--------FQDEY-----SLEEVMKSKPVFD---FLTILQCCPTSDGAAAA 234
Cdd:PRK05790 178 FalasqqkAEAAIKAGRFKdeiVPVTIKQrkgdpvvvDTDEHprpdtTAESLAKLRPAFDkdgTVTAGNASGINDGAAAV 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 235 ILSSEEFVQQYGLQSKAvEIVAQemmtdlpstfeeksiiKVVGYDMSK------EAARRCYEKSGLTPNDVDVIELHDCF 308
Cdd:PRK05790 258 VVMSEAKAKELGLTPLA-RIVSY----------------AVAGVDPAImgigpvPAIRKALEKAGWSLADLDLIEINEAF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 45476581 309 SVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATG 361
Cdd:PRK05790 321 AAQALAVEKELGLDPE------------------KVNVNGGAIALGHPIGASG 355
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
12-405 |
9.58e-14 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 73.20 E-value: 9.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 12 RRVFVVGVGMT---KFMkpGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYgDSTSGQR-AIYHSLGlTGIP- 86
Cdd:PLN02644 1 RDVCIVGVARTpigGFL--GSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVL-SANLGQApARQAALG-AGLPp 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 87 ---IINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKME-------RGSIGTKFSDRTTP------------TDKHI 144
Cdd:PLN02644 77 stiCTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSnapkylpEARKGSRLGHDTVVdgmlkdglwdvyNDFGM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 145 ----EVLIDKYGLS-----AHPITPQMFGYAGKE--HMEKYGTKVEHFAKIGwknhKHSVNNTYSQFQDEYSLEEVMKSK 213
Cdd:PLN02644 157 gvcaELCADQYSISreeqdAYAIQSYERAIAAQEagAFAWEIVPVEVPGGRG----RPSVIVDKDEGLGKFDPAKLRKLR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 214 PVFD----FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVEI----VAQ--EMMTDLPSTfeeksiikvvgydmske 283
Cdd:PLN02644 233 PSFKedggSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRgyadAAQapELFTTAPAL----------------- 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 284 AARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGqggtlvdrgdntyggkwvINPSGGLISKGHPLGATGLA 363
Cdd:PLN02644 296 AIPKALKHAGLEASQVDYYEINEAFSVVALANQKLLGLDPEK------------------VNVHGGAVSLGHPIGCSGAR 357
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 45476581 364 QCAELCWQLRGEAGKRQVPGAkvalqHNlGLGGAVVVTLYRM 405
Cdd:PLN02644 358 ILVTLLGVLRSKNGKYGVAGI-----CN-GGGGASAIVVELM 393
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
11-361 |
2.01e-13 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 72.05 E-value: 2.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFMKPGGENSRDYP-DMAKEAGQKALEDAQIPYSAVEQACVGYVygDSTSGQ-----RAIYHSLGLT- 83
Cdd:PRK07801 1 MAEAYIVDAVRTPVGKRKGGLAGVHPaDLGAHVLKGLVDRTGIDPAAVDDVIFGCV--DTIGPQagniaRTSWLAAGLPe 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 84 GIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTK--------FSDRTTPTDKHIEvlidKYGlsA 155
Cdd:PRK07801 79 EVPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAmtageqlgFTSPFAESKGWLH----RYG--D 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 156 HPITPqmfgYAGKEHM-EKYGTKVEHFAKIGWKNHKHSVNNTYS-QFQDEY---------------SLEEVMKSKPVFD- 217
Cdd:PRK07801 153 QEVSQ----FRGAELIaEKWGISREEMERFALESHRRAFAAIRAgRFDNEIvpvggvtvdegpretSLEKMAGLKPLVEg 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 218 -FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTP 296
Cdd:PRK07801 229 gRLTAAVASQISDGASAVLLASERAVKRHGLTPRA-RIHHLSVRGDDPVFMLTAPI----------PATRYALEKTGLSI 297
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45476581 297 NDVDVIELHDCFSVNELITYEALGLCPEGqggtlvdrgdntyggkwvINPSGGLISKGHPLGATG 361
Cdd:PRK07801 298 DDIDVVEINEAFAPVVLAWLKETGADPAK------------------VNPNGGAIALGHPLGATG 344
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
205-361 |
1.13e-12 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 69.65 E-value: 1.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 205 SLEEVMKSKPVF---DFLTILQCCPTSDGAAAAILSSEEFVQQYGLQ------SKAVEIVAQEMMTDLPStfeeksiikv 275
Cdd:PRK07851 237 TYEKVSQLKPVFrpdGTVTAGNACPLNDGAAAVVIMSDTKARELGLTplarivSTGVSGLSPEIMGLGPV---------- 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 276 vgydmskEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLcPEgqggtlvDRgdntyggkwvINPSGGLISKGH 355
Cdd:PRK07851 307 -------EASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGI-DE-------DK----------LNVSGGAIALGH 361
|
....*.
gi 45476581 356 PLGATG 361
Cdd:PRK07851 362 PFGMTG 367
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
201-379 |
2.98e-12 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 68.44 E-value: 2.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 201 QDEY-----SLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVEI------VAQEMMTDLPST 266
Cdd:PRK09050 222 RDEHprpetTLEALAKLKPVFRpdgTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILgmatagVEPRIMGIGPAP 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 267 feeksiikvvgydmskeAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLcpegqggtlVDRGDNtyggkwvINP 346
Cdd:PRK09050 302 -----------------ATRKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGL---------ADDDAR-------VNP 348
|
170 180 190
....*....|....*....|....*....|....*
gi 45476581 347 SGGLISKGHPLGATG--LAQCAELcwQLRGEAGKR 379
Cdd:PRK09050 349 NGGAIALGHPLGMSGarLVLTALH--QLERTGGRY 381
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
284-400 |
2.70e-11 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 60.73 E-value: 2.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 284 AARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATGLA 363
Cdd:pfam02803 27 AIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPE------------------KVNVNGGAIALGHPLGASGAR 88
|
90 100 110
....*....|....*....|....*....|....*..
gi 45476581 364 QCAELCWQLRGEAGKRQVpgakVALQHNLGLGGAVVV 400
Cdd:pfam02803 89 ILVTLLHELKRRGGKYGL----ASLCIGGGQGVAMII 121
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
37-138 |
2.87e-11 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 64.75 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALEDAQIPYSAVEQACVGYVYGD----STSGQraIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGL 112
Cdd:COG0332 53 DLAVEAARKALEAAGIDPEDIDLIIVATVTPDylfpSTACL--VQHKLGAKNAAAFDINAACSGFVYALSVAAALIRSGQ 130
|
90 100
....*....|....*....|....*.
gi 45476581 113 ANCVLALGFEKMERgsiGTKFSDRTT 138
Cdd:COG0332 131 AKNVLVVGAETLSR---IVDWTDRST 153
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
82-361 |
4.63e-11 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 64.60 E-value: 4.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 82 LTGIPI----INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMerGSIG-TKFSDRTTPTDKHIEVLIDKYGLSA- 155
Cdd:PRK08947 75 LAGIPHsvpaVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHM--GHVPmNHGVDFHPGLSKNVAKAAGMMGLTAe 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 156 -----HPITPQM---FGYagKEHMEKYGTKVE-HFAKIGWKNHKHSVNNTYSQFQD------EYSLEEVMKSKPVFD--- 217
Cdd:PRK08947 153 mlgkmHGISREQqdaFAA--RSHQRAWAATQEgRFKNEIIPTEGHDADGVLKLFDYdevirpETTVEALAALRPAFDpvn 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 218 -FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVeIVAqemMTdlpstfeeksiikVVGYDMS------KEAARRCYE 290
Cdd:PRK08947 231 gTVTAGTSSALSDGASAMLVMSESRAKELGLKPRAR-IRS---MA-------------VAGCDPSimgygpVPATQKALK 293
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45476581 291 KSGLTPNDVDVIELHDCFSVNELITYEALGlcpegqggtLVDRGDNTyggkwvINPSGGLISKGHPLGATG 361
Cdd:PRK08947 294 RAGLSISDIDVFELNEAFAAQSLPCLKDLG---------LLDKMDEK------VNLNGGAIALGHPLGCSG 349
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
11-392 |
5.65e-11 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 64.33 E-value: 5.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 11 LRRVFVVGVGMTKFMkPGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVG---YVYGDSTSGQRAIyHSLGltGIPI 87
Cdd:PRK07937 1 MRDVAVVGFAQAPHV-RRTDGTTNGVEMLMPCFAELYAELGITKSDIGFWCSGssdYLAGRAFSFISAI-DSIG--AVPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 88 INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKmerGSIGTkfSDRTTPTDkhievlIDKYGLSahPITPQMFGYAG 167
Cdd:PRK07937 77 INESHVEMDAAWALYEAWVKLLTGEVDTALVYGFGK---SSAGT--LRRVLALQ------LDPYTVA--PLWPDSVSMAG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 168 ---KEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQfqDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEfvqq 244
Cdd:PRK07937 144 lqaRAGLDAGKWTEEQMAEVAARSRADARRNPSAE--PSISVDELLARPYFADPLRRHDIAPITDGAAAVVLAAGD---- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 245 yglqsKAVEIVAQEM------------------MTDLPSTfeeksiikvvgydmsKEAARRCyekSGLTPNDVDVIELHD 306
Cdd:PRK07937 218 -----RARELRERPAwitgiehriespslgardLTRSPST---------------ALAAEAA---TGGDAGGVDVAELHA 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 307 CFSVNELITYEALGLcpegqggtlvdrGDNTyggkwVINPSGGLISkGHPLGATGLAQCAELCWQ-LRGEAGkRQVPGAK 385
Cdd:PRK07937 275 PFTHQELILREALGL------------GDKT-----KVNPSGGALA-ANPMFAAGLERIGEAARHiWDGSAR-RALAHAT 335
|
....*....
gi 45476581 386 V--ALQHNL 392
Cdd:PRK07937 336 SgpALQQNL 344
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
229-361 |
6.06e-11 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 64.41 E-value: 6.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 229 DGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCF 308
Cdd:PRK06025 276 DGAAALLLASKAYAEKHGLKPRA-RIVAMANMGDDPTLMLNAPV----------PAAKKVLAKAGLTKDDIDLWEINEAF 344
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 45476581 309 SVNELITYEALGLcpegqggtlvDRGDntyggkwvINPSGGLISKGHPLGATG 361
Cdd:PRK06025 345 AVVAEKFIRDLDL----------DRDK--------VNVNGGAIALGHPIGATG 379
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
84-361 |
2.15e-10 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 62.67 E-value: 2.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 84 GIPI----INVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSI-------GTKFSDrTTPTDKHIEVLIDKYG 152
Cdd:PRK09051 76 GVPQetpaFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYllpaarwGARMGD-AKLVDMMVGALHDPFG 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 153 lsahpitpqmfgyagKEHM--------EKYGTKVEH---FAKIGWKNHKHSVNNTYSQFQ-----------------DEY 204
Cdd:PRK09051 155 ---------------TIHMgvtaenvaAKYGISREAqdaLALESHRRAAAAIAAGYFKDQivpveiktrkgevvfdtDEH 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 205 -----SLEEVMKSKPVF--DFLTIlqccpTS-------DGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFEEK 270
Cdd:PRK09051 220 vradtTLEDLAKLKPVFkkENGTV-----TAgnasginDGAAAVVLAEADAAEARGLKPLA-RLVGYAHAGVDPEYMGIG 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 271 SIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEGqggtlvdrgdntyggkwvINPSGGL 350
Cdd:PRK09051 294 PV----------PATQKALERAGLTVADLDVIEANEAFAAQACAVTRELGLDPAK------------------VNPNGSG 345
|
330
....*....|.
gi 45476581 351 ISKGHPLGATG 361
Cdd:PRK09051 346 ISLGHPVGATG 356
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
36-400 |
4.32e-10 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 61.58 E-value: 4.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVYgDSTSGQRAIYHSLGLTGIPI----INVNNNCSTGSTALFMAHQLIQGG 111
Cdd:PRK06633 28 PMLAAHLIKDILQNSKIDPALVNEVILGQVI-TGGSGQNPARQTLIHAGIPKevpgYTINKVCGSGLKSVALAANSIMTG 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVLALGFEKMERG------SIGTKFSDRTTPTDKHIEVLIDKY-----GLSAHPITPQmFGYAGKEHMEKYGTKVEH 180
Cdd:PRK06633 107 DNEIVIAGGQENMSLGmhgsyiRAGAKFGDIKMVDLMQYDGLTDVFsgvfmGITAENISKQ-FNISRQEQDEFALSSHKK 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 181 FAKIG----WKNH----KHSVNNTYSQF-QDE-----YSLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILSSEEFVQ 243
Cdd:PRK06633 186 AAKAQlagiFKDEilpiEVTIKKTTSLFdHDEtvrpdTSLEILSKLRPAFDkngVVTAGNASSINDGAACLMVVSEEALK 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 244 QYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALglcp 323
Cdd:PRK06633 266 KHNLTPLA-RIVSYASAGVDPSIMGTAPV----------PASQKALSKAGWSVNDLEVIEVNEAFAAQSIYVNREM---- 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 324 egqggtlvdrgdntyggKW---VINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVpgakVALQHNLGLGGAVVV 400
Cdd:PRK06633 331 -----------------KWdmeKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGL----VTLCIGGGMGMAMCV 389
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
85-361 |
6.37e-10 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 61.05 E-value: 6.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 85 IPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGtkfSD-RTTPTDKhiEVLIDKY----GLSAHPIT 159
Cdd:PRK08242 82 VPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMG---SDgGAWAMDP--STNFPTYfvpqGISADLIA 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 160 pQMFGYaGKEHMEKYGTKVEHFAKIGWKNH--KHSV------NNTYSQFQDEY-----SLEEVMKSKPVFDFL------- 219
Cdd:PRK08242 157 -TKYGF-SREDVDAYAVESQQRAAAAWAEGyfAKSVvpvkdqNGLTILDHDEHmrpgtTMESLAKLKPSFAMMgemggfd 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 220 -TILQCCPT----------------SDGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPStfeeksiIKVVGydmSK 282
Cdd:PRK08242 235 aVALQKYPEverinhvhhagnssgiVDGAAAVLIGSEEAGKALGLKPRA-RIVATATIGSDPT-------IMLTG---PV 303
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 45476581 283 EAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATG 361
Cdd:PRK08242 304 PATRKALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHD------------------KVNVNGGAIAMGHPLGATG 364
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
37-138 |
7.56e-10 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 60.25 E-value: 7.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALEDAQIpySAVEQACVgyVYGDSTSGQRA------IYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQG 110
Cdd:cd00830 52 DLAVEAAKKALEDAGI--DADDIDLI--IVATSTPDYLFpataclVQARLGAKNAAAFDINAACSGFLYGLSTAAGLIRS 127
|
90 100
....*....|....*....|....*...
gi 45476581 111 GLANCVLALGFEKMERgsiGTKFSDRTT 138
Cdd:cd00830 128 GGAKNVLVVGAETLSR---ILDWTDRST 152
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
22-400 |
1.47e-09 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 60.18 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 22 TKFMKPGGENSRDYPD-MAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIYHSLGLTGIPI----INVNNNCST 96
Cdd:PRK08131 12 SPFGRHAGALASVRPDdLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPVtvpgQTVNRLCAS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 97 GSTALFMAHQLIQGGLANCVLALGFEKMER-----GSIGTKFSDRTTPTDKHI------EVLIDKYGLSAHPITPQ---- 161
Cdd:PRK08131 92 GLAAVIDAARAITCGEGDLYLAGGVESMSRapfvmGKAESAFSRDAKVFDTTIgarfpnPKIVAQYGNDSMPETGDnvaa 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 162 MFG--------YAGKEHMEKYGTKVEHF---------AKIGWKNHKHSVNntysqfQDEY-----SLEEVMKSKPVFD-- 217
Cdd:PRK08131 172 EFGisredadrFAAQSQAKYQAAKEEGFfadeitpieVPQGRKLPPKLVA------EDEHprpssTVEALTKLKPLFEgg 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 218 FLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPStfeeksiIKVVGydmSKEAARRCYEKSGLTPN 297
Cdd:PRK08131 246 VVTAGNASGINDGAAALLIGSRAAGEKYGLKPMA-RILSSAAAGVEPR-------IMGIG---PVEAIKKALARAGLTLD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 298 DVDVIELHDCFSVNELITYEALGlcpegqggtlVDRGDNTyggkwvINPSGGLISKGHPLGATGlaqcAELCWQLRGEAG 377
Cdd:PRK08131 315 DMDIIEINEAFASQVLGCLKGLG----------VDFDDPR------VNPNGGAIAVGHPLGASG----ARLALTAARELQ 374
|
410 420
....*....|....*....|...
gi 45476581 378 KRQVPGAKVALQHNLGLGGAVVV 400
Cdd:PRK08131 375 RRGKRYAVVSLCIGVGQGLAMVI 397
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
42-361 |
4.00e-09 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 58.58 E-value: 4.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 42 AGQKA-LEDAQIPYSAVEQ---ACVGYVYGDSTSGQRAIYHSLGL---TGIPIINVNnnCSTGSTALFMAHQLIQGGLAN 114
Cdd:PRK07850 32 AVQRAvLDRAGIDPGDVEQvigGCVTQAGEQSNNITRTAWLHAGLpyhVGATTIDCQ--CGSAQQANHLVAGLIAAGAID 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 115 CVLALGFEKMERGSIGTKFSDRTT---PTDKHI---------EVLIDKYGLSahpitpqmfgyagKEHMEKYGTKVEHFA 182
Cdd:PRK07850 110 VGIACGVEAMSRVPLGANAGPGRGlprPDSWDIdmpnqfeaaERIAKRRGIT-------------REDVDAFGLRSQRRA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 183 KIGWKNHK---------------------HSVNNTYSQFQDEYSLEEVMKSKPVFD--FLTILQCCPTSDGAAAAILSSE 239
Cdd:PRK07850 177 AQAWAEGRfdreispvqapvldeegqptgETRLVTRDQGLRDTTMEGLAGLKPVLEggIHTAGTSSQISDGAAAVLWMDE 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 240 EFVQQYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCFSvnelityeAL 319
Cdd:PRK07850 257 DRARALGLRPRA-RIVAQALVGAEPYYHLDGPV----------QATAKVLEKAGMKIGDIDLVEINEAFA--------SV 317
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 45476581 320 GLCPEGQGGTLVDRgdntyggkwvINPSGGLISKGHPLGATG 361
Cdd:PRK07850 318 VLSWAQVHEPDMDK----------VNVNGGAIALGHPVGSTG 349
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
37-379 |
4.17e-09 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 58.59 E-value: 4.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALEDAQIPYSAVEQA---CVGYVYGDSTS-GQRAIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGL 112
Cdd:PRK06504 28 DLAAQVLDALVDRSGADPALIEDVimgCVSQVGEQATNvARNAVLASKLPESVPGTSIDRQCGSSQQALHFAAQAVMSGT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 113 ANCVLALGFEKMERGSIGTKFSdrttptdkhievLIDKYGLsAHPITPQM--------FG-YAGKEHM-EKYGTKVEHFA 182
Cdd:PRK06504 108 MDIVIAAGVESMTRVPMGSPST------------LPAKNGL-GHYKSPGMeerypgiqFSqFTGAEMMaKKYGLSKDQLD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 183 KIGWKNHKHSVNNTYSQ-FQDEY-------------------------SLEEVMKSKPVFD-----FLTILQCCptsDGA 231
Cdd:PRK06504 175 EFALQSHQRAIAATQAGkFKAEIvpleitradgsgemhtvdegirfdaTLEGIAGVKLIAEggrltAATASQIC---DGA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 232 AAAILSSEEFVQQYGLQSKAvEIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCFSVN 311
Cdd:PRK06504 252 SGVMVVNERGLKALGVKPLA-RIHHMTVIGGDPVIMLEAPL----------PATERALKKAGMKIDDIDLYEVNEAFASV 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45476581 312 ELITYEALGLCPEGqggtlvdrgdntyggkwvINPSGGLISKGHPLGATGLAQCAELCWQLRgEAGKR 379
Cdd:PRK06504 321 PLAWLKATGADPER------------------LNVNGGAIALGHPLGASGTKLMTTLVHALK-QRGKR 369
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
36-382 |
8.44e-09 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 57.59 E-value: 8.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVY----GDSTSGQRAIYHSLGLtGIPIINVNNNCSTGSTALFMAHQLIQGG 111
Cdd:PRK06954 32 PQLGAAAIAAAVERAGLKPEQIDEVVMGCVLpagqGQAPARQAALGAGLPL-SVGCTTVNKMCGSGMRAAMFAHDMLVAG 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVLALGFEKME-------RGSIGTKFSDRTTPTDKHIEVLIDKYGLSahpitpQMFGYAGKEHMEKYGTKVEH---F 181
Cdd:PRK06954 111 SVDVIVAGGMESMTnapyllpKARGGMRMGHGQVLDHMFLDGLEDAYDKG------RLMGTFAEECAGEYGFTREAqdaF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 182 AKIGWKNHKHSVNNTYSQFQ-----------------DE----YSLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILS 237
Cdd:PRK06954 185 AIESLARAKRANEDGSFAWEiapvtvagkkgdtvidrDEqpfkANPEKIPTLKPAFSktgTVTAANSSSISDGAAALVMM 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 238 SEEFVQQYGLQSKAVeIVAQEMMTDLPSTFEEKSIikvvgydmskEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYE 317
Cdd:PRK06954 265 RASTAKRLGLAPLAR-VVGHSTFAQAPSKFTTAPV----------GAIRKLFEKNGWRAAEVDLFEINEAFAVVTMAAMK 333
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45476581 318 ALGLCPEGqggtlvdrgdntyggkwvINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVP 382
Cdd:PRK06954 334 EHGLPHEK------------------VNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVA 380
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
205-368 |
1.41e-08 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 57.22 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 205 SLEEVMKSKPVFDF-----LTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVEIVAQEMMTDLpstfeeksiikVVGYD 279
Cdd:PRK09268 237 SLEKLAKLKPVFGKggratMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVDF-----------VHGKE 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 280 ---MSKE-AARRCYEKSGLTPNDVDVIELHDCFSVNELIT---YEALGLCPE--GQGGTL--VDRGDntyggkwvINPSG 348
Cdd:PRK09268 306 gllMAPAyAVPRLLARNGLTLQDFDFYEIHEAFASQVLATlkaWEDEEYCRErlGLDAPLgsIDRSK--------LNVNG 377
|
170 180
....*....|....*....|...
gi 45476581 349 GLISKGHPLGATG---LAQCAEL 368
Cdd:PRK09268 378 SSLAAGHPFAATGgriVATLAKL 400
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
47-365 |
1.62e-08 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 57.08 E-value: 1.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 47 LEDAQIPYSAVEQACVGYVYGDSTsgQRAIYHSLG--LTGIP----IINVNNNCSTGSTALFMAHQLIQGGLANCVLALG 120
Cdd:PLN02287 83 VEKTGLNPSEVGDIVVGTVLAPGS--QRANECRMAafYAGFPetvpVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAG 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 121 FEKM------ERGSIGTKFSDRTTPTDKHIEVlidkyGLSAHPITpqmfgyagkehmEKYGTKVEHFAKIGWKNHKHSVN 194
Cdd:PLN02287 161 VESMttnpmaWEGGVNPRVESFSQAQDCLLPM-----GITSENVA------------ERFGVTREEQDQAAVESHRKAAA 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 195 NTYS-QFQDEY------------------------------SLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILSSEE 240
Cdd:PLN02287 224 ATASgKFKDEIvpvhtkivdpktgeekpivisvddgirpntTLADLAKLKPVFKkngTTTAGNSSQVSDGAGAVLLMKRS 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 241 FVQQYGL------QSKAVEIVAQEMMTDLPSTfeekSIIKVVgydmskeaarrcyEKSGLTPNDVDVIELHDCFSVNELI 314
Cdd:PLN02287 304 VAMQKGLpilgvfRSFAAVGVDPAVMGIGPAV----AIPAAV-------------KAAGLELDDIDLFEINEAFASQFVY 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 45476581 315 TYEALGLCPEGqggtlvdrgdntyggkwvINPSGGLISKGHPLGATGlAQC 365
Cdd:PLN02287 367 CCKKLGLDPEK------------------VNVNGGAIALGHPLGATG-ARC 398
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
36-361 |
4.43e-08 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 55.28 E-value: 4.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 36 PDMAKEAGQKALEDAQIPYSAVEQACVGYVY----GDSTSGQRAIYHSLGLTgIPIINVNNNCSTGSTALFMAHQLIQGG 111
Cdd:PRK05656 27 VELGAAVIRRLLEQTGLDPAQVDEVILGQVLtagaGQNPARQAAIKAGLPHS-VPAMTLNKVCGSGLKALHLAAQAIRCG 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 112 LANCVLALGFEKMERGS-----------------IGTKFSDR--TTPTDKHI----EVLIDKYGLS-----AHPITPQMF 163
Cdd:PRK05656 106 DAEVIIAGGQENMSLAPyvlpgartglrmghaqlVDSMITDGlwDAFNDYHMgitaENLVEKYGISreaqdAFAAASQQK 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 164 GYAGKEHmekyGTKVEHFAKIGWKNHKHS--VNNTYSQFQDEYSLEEVMKSKPVFD---FLTILQCCPTSDGAAAAILSS 238
Cdd:PRK05656 186 AVAAIEA----GRFDDEITPILIPQRKGEplAFATDEQPRAGTTAESLAKLKPAFKkdgSVTAGNASSLNDGAAAVLLMS 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 239 EEFVQQYGLQSKAvEIVAQEMMTDLPStfeeksiIKVVGydmSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEA 318
Cdd:PRK05656 262 AAKAKALGLPVLA-KIAAYANAGVDPA-------IMGIG---PVSATRRCLDKAGWSLAELDLIEANEAFAAQSLAVGKE 330
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 45476581 319 LGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATG 361
Cdd:PRK05656 331 LGWDAA------------------KVNVNGGAIALGHPIGASG 355
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
85-402 |
2.95e-07 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 52.83 E-value: 2.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 85 IPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMergSIGTKFSDRTTPTDKHIEVLIDKYglsahpitpQMFG 164
Cdd:PRK07661 81 VPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESM---SLVPMMGHVVRPNPRLVEAAPEYY---------MGMG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 165 YAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQ-FQDEY---------------------------------SLEEVM 210
Cdd:PRK07661 149 HTAEQVAVKYGISREDQDAFAVRSHQRAAKALAEGkFADEIvpvdvtlrtvgennklqeetitfsqdegvradtTLEILG 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 211 KSKPVFDF---LTILQCCPTSDGAAAAILSSEEFVQQYGLQ------SKAVEIVAQEMMTDLPStfeeksiikvvgydms 281
Cdd:PRK07661 229 KLRPAFNVkgsVTAGNSSQMSDGAAAVLLMDREKAESDGLKplakfrSFAVAGVPPEVMGIGPI---------------- 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 282 kEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALGLCPEgqggtlvdrgdntyggkwVINPSGGLISKGHPLGATG 361
Cdd:PRK07661 293 -AAIPKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDEE------------------KVNVNGGAIALGHPLGCTG 353
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 45476581 362 laqcAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAVVVTL 402
Cdd:PRK07661 354 ----AKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFEL 390
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
4-120 |
6.12e-07 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 51.66 E-value: 6.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 4 VALKSPRLRRVFVVGVGmTKFMKPGGENSrdyPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIY--HSLG 81
Cdd:cd00827 21 LAEGLGVDPGKYTTGIG-QRHMAGDDEDV---PTMAVEAARRALERAGIDPDDIGLLIVATESPIDKGKSAATYlaELLG 96
|
90 100 110
....*....|....*....|....*....|....*....
gi 45476581 82 LTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALG 120
Cdd:cd00827 97 LTNAEAFDLKQACYGGTAALQLAANLVESGPWRYALVVA 135
|
|
| Alkyl_sulf_C |
pfam14864 |
Alkyl sulfatase C-terminal; This domain is found at the C-terminus of alkyl sulfatases. ... |
471-528 |
9.42e-07 |
|
Alkyl sulfatase C-terminal; This domain is found at the C-terminus of alkyl sulfatases. Together with the N-terminal catalytic domain, this domain forms a hydrophobic chute and may recruit hydrophobic substrates.
Pssm-ID: 405542 [Multi-domain] Cd Length: 124 Bit Score: 47.96 E-value: 9.42e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45476581 471 EATWVVDVKNGkgsVL----PNSDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGN 528
Cdd:pfam14864 43 DEQYRLTLSNG---VLtyrkGRQADDADATLTLTRADLLALLLGKATLGKLIAAGKIKVEGD 101
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
229-361 |
3.08e-06 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 49.60 E-value: 3.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 229 DGAAAAILSSEEFVQQYGLQ------SKAVEIVAQEMMTdlpstfeeksiIKVVGydmskeAARRCYEKSGLTPNDVDVI 302
Cdd:PRK06205 259 DAAAACLVTTEDKAEELGLRplarlvSWAVAGVEPSRMG-----------IGPVP------ATEKALARAGLTLDDIDLI 321
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 45476581 303 ELHDCFSVNELITYEALGLCPEGqggtlVDRgdntyggkwvINPSGGLISKGHPLGATG 361
Cdd:PRK06205 322 ELNEAFAAQVLAVLKEWGFGADD-----EER----------LNVNGSGISLGHPVGATG 365
|
|
| PRK09352 |
PRK09352 |
beta-ketoacyl-ACP synthase 3; |
37-138 |
5.27e-06 |
|
beta-ketoacyl-ACP synthase 3;
Pssm-ID: 236475 [Multi-domain] Cd Length: 319 Bit Score: 48.53 E-value: 5.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 37 DMAKEAGQKALEDAQIPYSAVEQACVGYVYGD----STSGQraIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGL 112
Cdd:PRK09352 54 DLATEAAKKALEAAGIDPEDIDLIIVATTTPDyafpSTACL--VQARLGAKNAAAFDLSAACSGFVYALSTADQFIRSGA 131
|
90 100
....*....|....*....|....*.
gi 45476581 113 ANCVLALGFEKMERgsIgTKFSDRTT 138
Cdd:PRK09352 132 YKNVLVIGAEKLSR--I-VDWTDRST 154
|
|
| BDS1 |
COG2015 |
Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily [Secondary ... |
472-538 |
9.07e-06 |
|
Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 441618 [Multi-domain] Cd Length: 629 Bit Score: 48.30 E-value: 9.07e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45476581 472 ATWVVDVKNGkgsVLPN----SDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGNMGLAMKLQNL 538
Cdd:COG2015 551 EKYLLELRNG---VLTYrkgpQADDADATLTLTRADLLALLLGKTTLDDLVASGGAKVEGDAAALARLLGL 618
|
|
| UbiJ |
COG3165 |
Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism]; ... |
485-538 |
1.42e-05 |
|
Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain [Coenzyme transport and metabolism];
Pssm-ID: 442398 Cd Length: 204 Bit Score: 46.01 E-value: 1.42e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 45476581 485 VLPNSDKKADCTITMADSDLLALMTGKmNPQSAFFQGKLKIAGNMGLAMKLQNL 538
Cdd:COG3165 58 VLGAWEGEADCTLTGSLSALLRLADAQ-DLTALIASGELRIEGDAQLAQQLSRL 110
|
|
| ACP_syn_III |
pfam08545 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl- ... |
90-138 |
2.43e-04 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.180, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430064 [Multi-domain] Cd Length: 80 Bit Score: 39.81 E-value: 2.43e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 45476581 90 VNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMergSIGTKFSDRTT 138
Cdd:pfam08545 3 INAACSGFVYALSTAAALIRSGRAKNVLVIGAETL---SKILDWTDRST 48
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
38-122 |
4.59e-04 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 42.53 E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 38 MAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIY--------------------------------HSLGLTGi 85
Cdd:cd00834 74 FALAAAEEALADAGLDPEELDPERIGVVIGSGIGGLATIEeayrallekgprrvspffvpmalpnmaagqvaIRLGLRG- 152
|
90 100 110
....*....|....*....|....*....|....*..
gi 45476581 86 PIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFE 122
Cdd:cd00834 153 PNYTVSTACASGAHAIGDAARLIRLGRADVVIAGGAE 189
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
42-122 |
7.90e-04 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 42.00 E-value: 7.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 42 AGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIYHS--------------------------------LGLTGiPIIN 89
Cdd:COG0304 78 AAREALADAGLDLDEVDPDRTGVIIGSGIGGLDTLEEAyrallekgprrvspffvpmmmpnmaaghvsirFGLKG-PNYT 156
|
90 100 110
....*....|....*....|....*....|...
gi 45476581 90 VNNNCSTGSTALFMAHQLIQGGLANCVLALGFE 122
Cdd:COG0304 157 VSTACASGAHAIGEAYRLIRRGRADVMIAGGAE 189
|
|
| PRK07204 |
PRK07204 |
beta-ketoacyl-ACP synthase III; |
38-170 |
7.68e-03 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 235964 Cd Length: 329 Bit Score: 38.66 E-value: 7.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45476581 38 MAKEAGQKALEDAQIPYSAVEQacvgyVYGDSTSGQRAI-------YHSLGL--TGIPIINVNNNCSTGSTALFMAHQLI 108
Cdd:PRK07204 55 MGAEAAKKAVEDAKLTLDDIDC-----IICASGTIQQAIpctasliQEQLGLqhSGIPCFDINSTCLSFITALDTISYAI 129
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45476581 109 QGGLANCVLALgfeKMERGSIGTKFSDRTTPT---DKHIEVLIDKYGLSAHPITPQMFGYAGKEH 170
Cdd:PRK07204 130 ECGRYKRVLII---SSEISSVGLNWGQNESCIlfgDGAAAVVITKGDHSSRILASHMETYSSGAH 191
|
|
| |
