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Conserved domains on  [gi|31981400|ref|NP_035941|]
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phenylalanine--tRNA ligase beta subunit isoform 1 [Mus musculus]

Protein Classification

phenylalanine--tRNA ligase beta subunit( domain architecture ID 1004798)

phenylalanine--tRNA ligase beta subunit is involved in the process of aminoacylation which attaching an amino acid to a tRNA

CATH:  3.30.56.10
EC:  6.1.1.20
Gene Ontology:  GO:0005524|GO:0046872|GO:0004826|GO:0003723

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02265 super family cl33446
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


The actual alignment was detected with superfamily member PLN02265:

Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 900.20  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    1 MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----HGKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   77 LEGLARGLQVFKERIKAPVYK-RVMPKGDIQKLVITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  236 IINGNHSKITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEHCENQFTVEAVEVVSPNGKSSTFPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  316 KKVGIRETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  475 FEISDVVVKDSGKDVGAKNYRHLCAVYYNKTPGFEIIHGLLDRIMQLLDVPPGE--ESGGYMIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 31981400  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
 
Name Accession Description Interval E-value
PLN02265 PLN02265
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 900.20  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    1 MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----HGKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   77 LEGLARGLQVFKERIKAPVYK-RVMPKGDIQKLVITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  236 IINGNHSKITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEHCENQFTVEAVEVVSPNGKSSTFPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  316 KKVGIRETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  475 FEISDVVVKDSGKDVGAKNYRHLCAVYYNKTPGFEIIHGLLDRIMQLLDVPPGE--ESGGYMIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 31981400  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
pheT_arch TIGR00471
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ...
 1-589 7.59e-167

phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 273096 [Multi-domain]  Cd Length: 551  Bit Score: 486.18  E-value: 7.59e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400     1 MPTVSVKRDLLFqalgRTYTDEEFDELCFEFGL---ELDEITSEKQIIskeqghgkaqgasdvvlyKIDVPANRYDLLCL 77
Cdd:TIGR00471   1 MPTVTVYKDDLE----DLLIGTDRDEILEELPMmgdEIEGFDEESPEI------------------KVEFNPNRPDLLSV 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    78 EGLARGLQVFKErIKAPVYKRVMPKGDIqKLVITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALV 157
Cdd:TIGR00471  59 EGLARSLRGYLG-IEKGLKSYDSKKGDV-KLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKV 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   158 AIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDnhlKHYLHIIESKPLYPVIYDSNGVVLSMPPII 237
Cdd:TIGR00471 137 AIGIHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHPKG---IRYAHIIEDSDKFPLILDSKDDVLSMPPII 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   238 NGNHSKITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEHCENQFTVeaVEVVSPNGkSSTFPELPYRKEMVRADLINKK 317
Cdd:TIGR00471 214 NSELTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITV--VEVERPDE-HLGQPNLAPRFMEVSVEYINSL 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   318 VGIRETPANLAKLLTRMCLKSEVigDGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLT 397
Cdd:TIGR00471 291 LGLNLSADEIAHSLKKMRLDAVQ--SDEKLKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVS 368

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   398 ELLRLDMAAAGFTEALTFALCSQEDIADKlgLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEI 477
Cdd:TIGR00471 369 DIIREIMVGLGFQEVIPLTLTSEEVNFKR--MRIEDNNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEI 446

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   478 SDVVVKDSGKDVGAKNYRHLCAVYYNKTPGFEIIHGLLDRIMQLLDVppgeesgGYMIKASAGSAFFPGRCAEIFVGGQS 557
Cdd:TIGR00471 447 GDVVVKDDKSETRSRVVTKLAVGITHSEANFNEIKSIVAALARELGI-------EYEIEESEHPSFIPGRGAKIVFEGKA 519

                         570       580       590
                  ....*....|....*....|....*....|..
gi 31981400   558 IGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:TIGR00471 520 IGHFGEIHPEVLTNFELEFPVSAFEVNIEVFL 551
tRNA_synthFbeta pfam17759
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ...
 377-585 1.03e-60

Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.


Pssm-ID: 465487 [Multi-domain]  Cd Length: 214  Bit Score: 200.47  E-value: 1.03e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   377 IQMTLPKTYTIANQ-FPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLDISATKAVHISNPKTAEFQVARTTLL 455
Cdd:pfam17759   1 IPSTLPKGPTTGGGlTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKD-LDKLLEDDPRRKAVKLANPLSEELSVMRTSLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   456 PGLLKTIAANRKMPLP-LKLFEISDVVVKDsGKDVGAKNYRHLCAVYYNKT-----------PGFEIIHGLLDRIMQLLD 523
Cdd:pfam17759  80 PGLLETLAYNLNRGNPdVRLFEIGRVFLPD-ELEELPREPRRLAGLLTGKRlpeswqgkarpVDFYDLKGIVEALLAALG 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31981400   524 VppgeesGGYMIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINI 585
Cdd:pfam17759 159 I------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
PheT COG0072
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ...
 56-589 1.47e-52

Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439842 [Multi-domain]  Cd Length: 793  Bit Score: 192.30  E-value: 1.47e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  56 GASDVVLyKIDVPANRYDLLCLEGLARGLQV-FKERIKAPVYK-RVMPKGDIQKLVITEETAKVRPFAvAAVLRNIKFTK 133
Cdd:COG0072 152 GLDDTVL-EIDLTPNRADCLSVRGVARELAAlLGAPLKLPAIEpEVPPAIDDPIPVEIEDPEACPRYA-GRVIRGVKVGP 229

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 134 drydSFIELQEKLHqnicrkralvAIG---------------------TH--DLDTLSGPFTytAKR-PSDIKFKPLNKt 189
Cdd:COG0072 230 ----SPLWMQERLR----------AAGirpinnvvditnyvmlelgqpLHafDLDKLKGGIV--VRRaREGEKLTTLDG- 292

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 190 KEYTaceLmniykTDNHLkhylhiieskplypVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC----------T--- 256
Cdd:COG0072 293 KERT---L-----DPDDL--------------VIADDEGPL-ALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarr 349

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 257 -------------GTDFTKAKIVLDIIVTMFSEHCENQFTVEAVEVVspngksstfPELPYRKE-MVRADLINKKVGIRE 322
Cdd:COG0072 350 lglhsdasyrferGVDPALTVAALERATQLILEIAGGEVGPGIVDVY---------PEPPEPKTiTLRLARINRLLGVEI 420

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 323 TPANLAKLLTRmcLKSEVIGDGNQIEVEIPPTRADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTEL 399
Cdd:COG0072 421 PAEEIEEILER--LGFEVEEDGDGLTVTVPSWRFDIEIEADLIEE--VAriYGYDNIPSTLPRaPLAGGGLTEAQRLRRR 496

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 400 LRLDMAAAGFTEALTFALCSQEDiADKLGLDisaTKAVHISNPKTAEFQVARTTLLPGLLKTIAAN--RKMPlPLKLFEI 477
Cdd:COG0072 497 VRRALAARGYQEVITYSFVSPED-ADLFGLR---REAVRLANPISEDLSVMRTSLLPGLLEAAAYNlnRGQK-DVRLFEI 571

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 478 SDVVVKDSGKDvgAKNYRHLCAVYY-NKTPG-----------FEIIhGLLDRIMQLLDVPpgeesgGYMIKASAGSAFFP 545
Cdd:COG0072 572 GRVFLPDEGEE--PREPLHLAGVLTgNREPEswggkarpvdfFDLK-GDVEALLAALGVP------KLEFEAAEHPALHP 642

                       570       580       590       600
                ....*....|....*....|....*....|....*....|....
gi 31981400 546 GRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:COG0072 643 GRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALL 686
PheRS_beta_core cd00769
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ...
 392-588 4.07e-52

Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.


Pssm-ID: 238392 [Multi-domain]  Cd Length: 198  Bit Score: 177.06  E-value: 4.07e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 392 PLNKLTELLRLDMAAAGFTEALTFALCSQEDIADklgLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMP-L 470
Cdd:cd00769   1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAEL---FDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnK 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 471 PLKLFEISDVVVKDSGkdvGAKNYRHLCAVYYNKT-----------PGFEIIHGLLDRIMQLLdvppgEESGGYMIKASA 539
Cdd:cd00769  78 PLRLFEIGRVFLKDED---GPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRAL-----GIIVEFELEELD 149

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 31981400 540 GSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPF 588
Cdd:cd00769 150 ADLFHPGRSAKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
B3_4 smart00873
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 118-279 1.04e-29

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 214876 [Multi-domain]  Cd Length: 174  Bit Score: 115.05  E-value: 1.04e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    118 RPFAVAAVLRNIKFTkdrYDSFIELQEKLHQNICRKRaLVAIGTHDLDTLSGPFTYTAKRPSDIKFK--PLNKTKEYTAC 195
Cdd:smart00873   1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPI-NNVVDITNYVSLETGQPLHAFDLDKIKGKdiPLRRAKEGEKF 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    196 ELMNiyKTDNHLKHYLHIIESKPLYPVIYDSNGV----------VLSMPPIINGNHS-KITVNTRNIFIECT-----GTD 259
Cdd:smart00873  77 ETLD--GKEYELDEGDLVIADDEGPLALAGVMGGeesevtenttVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVD 154

                          170       180
                   ....*....|....*....|
gi 31981400    260 FTKAKIVLDIIVTMFSEHCE 279
Cdd:smart00873 155 PELVELALDRAAALLLEICG 174
 
Name Accession Description Interval E-value
PLN02265 PLN02265
probable phenylalanyl-tRNA synthetase beta chain
 1-589 0e+00

probable phenylalanyl-tRNA synthetase beta chain


Pssm-ID: 215149 [Multi-domain]  Cd Length: 597  Bit Score: 900.20  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    1 MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKQIISKEQG----HGKAQGASDVVLYKIDVPANRYDLLC 76
Cdd:PLN02265   1 MPTVSVGRDRLFAALGRTYTQEEFDELCFEFGIELDDVTTEKAIIRKEKHldeeEDGGADDDEEVIYKIDVPANRYDLLC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   77 LEGLARGLQVFKERIKAPVYK-RVMPKGDIQKLVITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRA 155
Cdd:PLN02265  81 LEGLARALRVFLGTEPIPTYRlAEISKGSILKMHVKPETSLIRPFVVCAVLRGVTFDEARYNSFIDLQDKLHQNICRRRT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  156 LVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIESKPLYPVIYDSNGVVLSMPP 235
Cdd:PLN02265 161 LVAIGTHDLDTLQGPFTYEALPPEDINFVPLKQTKSFRADELMEFYKSDMKLKKFLHIIENSPVFPVIYDSNRTVLSLPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  236 IINGNHSKITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEHCENQFTVEAVEVVSPNGKSSTFPELPYRKEMVRADLIN 315
Cdd:PLN02265 241 IINGAHSAITLDTKNVFIECTATDLTKAKIVLNTMVTMFSEYCARKFEVEPVEVVYPDGKSTVYPDLSVRTMEVDLSYIN 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  316 KKVGIRETPANLAKLLTRMCLKSEVIG-DGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLN 394
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKMQLQAEQSSdDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  395 KLTELLRLDMAAAGFTEALTFALCSQEDIADKLGLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKL 474
Cdd:PLN02265 401 QFSDLLRAEVAMAGFTEVLTWILCSHKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKPIKL 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  475 FEISDVVVKDSGKDVGAKNYRHLCAVYYNKTPGFEIIHGLLDRIMQLLDVPPGE--ESGGYMIKASAGSAFFPGRCAEIF 552
Cdd:PLN02265 481 FEVSDVVLLDESKDVGARNSRRLAALYCGTTSGFEVIHGLVDRIMEVLGIPFVEigDNNGYYVEPSNEPEYFPGRQASII 560

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 31981400  553 VGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PLN02265 561 YKGKHVGTFGIVHPEVLNNFDIPDPCSFLELDLEPLL 597
pheT_arch TIGR00471
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ...
 1-589 7.59e-167

phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 273096 [Multi-domain]  Cd Length: 551  Bit Score: 486.18  E-value: 7.59e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400     1 MPTVSVKRDLLFqalgRTYTDEEFDELCFEFGL---ELDEITSEKQIIskeqghgkaqgasdvvlyKIDVPANRYDLLCL 77
Cdd:TIGR00471   1 MPTVTVYKDDLE----DLLIGTDRDEILEELPMmgdEIEGFDEESPEI------------------KVEFNPNRPDLLSV 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    78 EGLARGLQVFKErIKAPVYKRVMPKGDIqKLVITEETAKVRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALV 157
Cdd:TIGR00471  59 EGLARSLRGYLG-IEKGLKSYDSKKGDV-KLTVDESVLQIRPFITGAVVKGIILNDKVLESLIELQEKLHWNIGRNRRKV 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   158 AIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDnhlKHYLHIIESKPLYPVIYDSNGVVLSMPPII 237
Cdd:TIGR00471 137 AIGIHDLDKVEFPFHYKAVSPNGIKFVPLNSDQEMTPDEILEEHPKG---IRYAHIIEDSDKFPLILDSKDDVLSMPPII 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   238 NGNHSKITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEHCENQFTVeaVEVVSPNGkSSTFPELPYRKEMVRADLINKK 317
Cdd:TIGR00471 214 NSELTKLTVNTRNLLIDVTGTDKTAVEITLNIACTMFADRGDGRITV--VEVERPDE-HLGQPNLAPRFMEVSVEYINSL 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   318 VGIRETPANLAKLLTRMCLKSEVigDGNQIEVEIPPTRADVIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLT 397
Cdd:TIGR00471 291 LGLNLSADEIAHSLKKMRLDAVQ--SDEKLKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPLINTIGRLKPLNKVS 368

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   398 ELLRLDMAAAGFTEALTFALCSQEDIADKlgLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEI 477
Cdd:TIGR00471 369 DIIREIMVGLGFQEVIPLTLTSEEVNFKR--MRIEDNNDVKVANPKTLEYTIVRTSLLPGLLETLSENKHHELPQKIFEI 446

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   478 SDVVVKDSGKDVGAKNYRHLCAVYYNKTPGFEIIHGLLDRIMQLLDVppgeesgGYMIKASAGSAFFPGRCAEIFVGGQS 557
Cdd:TIGR00471 447 GDVVVKDDKSETRSRVVTKLAVGITHSEANFNEIKSIVAALARELGI-------EYEIEESEHPSFIPGRGAKIVFEGKA 519

                         570       580       590
                  ....*....|....*....|....*....|..
gi 31981400   558 IGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:TIGR00471 520 IGHFGEIHPEVLTNFELEFPVSAFEVNIEVFL 551
tRNA_synthFbeta pfam17759
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ...
 377-585 1.03e-60

Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.


Pssm-ID: 465487 [Multi-domain]  Cd Length: 214  Bit Score: 200.47  E-value: 1.03e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   377 IQMTLPKTYTIANQ-FPLNKLTELLRLDMAAAGFTEALTFALCSQEDiADKLGLDISATKAVHISNPKTAEFQVARTTLL 455
Cdd:pfam17759   1 IPSTLPKGPTTGGGlTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKD-LDKLLEDDPRRKAVKLANPLSEELSVMRTSLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   456 PGLLKTIAANRKMPLP-LKLFEISDVVVKDsGKDVGAKNYRHLCAVYYNKT-----------PGFEIIHGLLDRIMQLLD 523
Cdd:pfam17759  80 PGLLETLAYNLNRGNPdVRLFEIGRVFLPD-ELEELPREPRRLAGLLTGKRlpeswqgkarpVDFYDLKGIVEALLAALG 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31981400   524 VppgeesGGYMIKASAGSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINI 585
Cdd:pfam17759 159 I------DDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
PheT COG0072
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ...
 56-589 1.47e-52

Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439842 [Multi-domain]  Cd Length: 793  Bit Score: 192.30  E-value: 1.47e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  56 GASDVVLyKIDVPANRYDLLCLEGLARGLQV-FKERIKAPVYK-RVMPKGDIQKLVITEETAKVRPFAvAAVLRNIKFTK 133
Cdd:COG0072 152 GLDDTVL-EIDLTPNRADCLSVRGVARELAAlLGAPLKLPAIEpEVPPAIDDPIPVEIEDPEACPRYA-GRVIRGVKVGP 229

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 134 drydSFIELQEKLHqnicrkralvAIG---------------------TH--DLDTLSGPFTytAKR-PSDIKFKPLNKt 189
Cdd:COG0072 230 ----SPLWMQERLR----------AAGirpinnvvditnyvmlelgqpLHafDLDKLKGGIV--VRRaREGEKLTTLDG- 292

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 190 KEYTaceLmniykTDNHLkhylhiieskplypVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC----------T--- 256
Cdd:COG0072 293 KERT---L-----DPDDL--------------VIADDEGPL-ALAGVMGGEDSEVTEETTDVLLESayfdpvsirrTarr 349

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 257 -------------GTDFTKAKIVLDIIVTMFSEHCENQFTVEAVEVVspngksstfPELPYRKE-MVRADLINKKVGIRE 322
Cdd:COG0072 350 lglhsdasyrferGVDPALTVAALERATQLILEIAGGEVGPGIVDVY---------PEPPEPKTiTLRLARINRLLGVEI 420

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 323 TPANLAKLLTRmcLKSEVIGDGNQIEVEIPPTRADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTEL 399
Cdd:COG0072 421 PAEEIEEILER--LGFEVEEDGDGLTVTVPSWRFDIEIEADLIEE--VAriYGYDNIPSTLPRaPLAGGGLTEAQRLRRR 496

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 400 LRLDMAAAGFTEALTFALCSQEDiADKLGLDisaTKAVHISNPKTAEFQVARTTLLPGLLKTIAAN--RKMPlPLKLFEI 477
Cdd:COG0072 497 VRRALAARGYQEVITYSFVSPED-ADLFGLR---REAVRLANPISEDLSVMRTSLLPGLLEAAAYNlnRGQK-DVRLFEI 571

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 478 SDVVVKDSGKDvgAKNYRHLCAVYY-NKTPG-----------FEIIhGLLDRIMQLLDVPpgeesgGYMIKASAGSAFFP 545
Cdd:COG0072 572 GRVFLPDEGEE--PREPLHLAGVLTgNREPEswggkarpvdfFDLK-GDVEALLAALGVP------KLEFEAAEHPALHP 642

                       570       580       590       600
                ....*....|....*....|....*....|....*....|....
gi 31981400 546 GRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:COG0072 643 GRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALL 686
PheRS_beta_core cd00769
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ...
 392-588 4.07e-52

Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.


Pssm-ID: 238392 [Multi-domain]  Cd Length: 198  Bit Score: 177.06  E-value: 4.07e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 392 PLNKLTELLRLDMAAAGFTEALTFALCSQEDIADklgLDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMP-L 470
Cdd:cd00769   1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAEL---FDGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKnK 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400 471 PLKLFEISDVVVKDSGkdvGAKNYRHLCAVYYNKT-----------PGFEIIHGLLDRIMQLLdvppgEESGGYMIKASA 539
Cdd:cd00769  78 PLRLFEIGRVFLKDED---GPEEEEHLAALLSGNRepeswqgkgrpVDFYDAKGILEALLRAL-----GIIVEFELEELD 149

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 31981400 540 GSAFFPGRCAEIFVGGQSIGKLGVLHPDVITKFELTMPCSSLEINIEPF 588
Cdd:cd00769 150 ADLFHPGRSAKIYVNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
pheT PRK00629
phenylalanyl-tRNA synthetase subunit beta; Reviewed
 56-589 5.12e-51

phenylalanyl-tRNA synthetase subunit beta; Reviewed


Pssm-ID: 234804 [Multi-domain]  Cd Length: 791  Bit Score: 188.07  E-value: 5.12e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   56 GASDVVLyKIDVPANRYDLLCLEGLARGLQV-FKERIKAPVYKRVMPKGDIQKLVITEETAKVRPFAvAAVLRNIKFTKD 134
Cdd:PRK00629 151 GLDDTVI-EISLTPNRADCLSVRGIARELAAlLGLPLKLPEIEPVPATIDDKLPVEIEDPDLCPRYA-GRVIKGVKNIAP 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  135 rydSFIELQEKLHQNICR-KRALVAI--------G--TH--DLDTLSGPFTytAKR-PSDIKFKPLNKtKEYTaceLmni 200
Cdd:PRK00629 229 ---SPLWLQERLRAAGIRpINNVVDItnyvmlelGqpLHafDLDKIGGGIV--VRRaKEGEKLTTLDG-KERT---L--- 296

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  201 ykTDNHLkhylhiieskplypVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIEC------------------T------ 256
Cdd:PRK00629 297 --DPEDL--------------VIADDKKPL-ALAGVMGGEDSEVTENTTNVLLESayfdpvsirktarrlglrTdasyrf 359

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  257 --GTDFTKAKIVLDIIVTMFSEHCENqftvEAVEVVSPNGKsstfpeLPYRKE-MVRADLINKKVGIRETPANLAKLLTR 333
Cdd:PRK00629 360 erGVDPALTLLALERATALILELGGG----EVVEGVVDVYP------LPKEPTiTLRLERINRLLGTEISDEEIVDILKR 429

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  334 MCLKSEVIGDGnQIEVEIPPTRADVIHACDIVEDaaIA--YGYNNIQMTLPK-TYTIANQFPLNKLTELLRLDMAAAGFT 410
Cdd:PRK00629 430 LGFEVTEVDGD-GLTVTVPSWRFDIEIEEDLVEE--VAriYGYDNIPSTPPVaALTMGGLTEAQRLLRRLRRALAALGYQ 506

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  411 EALTFALCSQEDiADKLGLDisaTKAVHISNPKTAEFQVARTTLLPGLLKTIAAN--RKMPLpLKLFEISDVVVKDSGKD 488
Cdd:PRK00629 507 EVITYSFVSPED-AKLFGLN---PEPLLLLNPISEELSVMRTSLLPGLLEAVAYNlnRGNKD-VALFEIGRVFLPDGDLP 581

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  489 vgaKNYRHLCAVYYNKTPG-----------FEIIhGLLDRIMQLLDVPPGEESggymiKASAGSAFFPGRCAEIFVGGQS 557
Cdd:PRK00629 582 ---REPEHLAGVLTGNRVEeswggkrpvdfFDLK-GDVEALLEALGLPEVEFV-----AEFEAAALHPGRSAEIYLDGKV 652

                        570       580       590
                 ....*....|....*....|....*....|..
gi 31981400  558 IGKLGVLHPDVITKFELTMPCSSLEINIEPFL 589
Cdd:PRK00629 653 IGFIGELHPKVLKKLDLPGRTYVFELDLDALL 684
PhetRS_B1 pfam18262
Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human ...
 1-90 4.94e-37

Phe-tRNA synthetase beta subunit B1 domain; This is the N-terminal domain found in human cytosolic phenylalanyl tRNA synthetase beta subunit.


Pssm-ID: 408077  Cd Length: 83  Bit Score: 132.16  E-value: 4.94e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400     1 MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKqiiskeqGHGKAQGASDVVLYKIDVPANRYDLLCLEGL 80
Cdd:pfam18262   1 MPTISVKKVRLFKVLGRVYTEEEFSDLCFEFGLELDEITSEE-------NQLKTSWRSEEVVYKIDIPANRYDLLCVEGL 73

                          90
                  ....*....|
gi 31981400    81 ARGLQVFKER 90
Cdd:pfam18262  74 ATALLIFKGK 83
B3_4 smart00873
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 118-279 1.04e-29

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 214876 [Multi-domain]  Cd Length: 174  Bit Score: 115.05  E-value: 1.04e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    118 RPFAVAAVLRNIKFTkdrYDSFIELQEKLHQNICRKRaLVAIGTHDLDTLSGPFTYTAKRPSDIKFK--PLNKTKEYTAC 195
Cdd:smart00873   1 CPRYLGRVIRGVKNT---RPSPEWLQERLHRAGIRPI-NNVVDITNYVSLETGQPLHAFDLDKIKGKdiPLRRAKEGEKF 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    196 ELMNiyKTDNHLKHYLHIIESKPLYPVIYDSNGV----------VLSMPPIINGNHS-KITVNTRNIFIECT-----GTD 259
Cdd:smart00873  77 ETLD--GKEYELDEGDLVIADDEGPLALAGVMGGeesevtenttVIFLEPAIFSPRTiRITARTLNLFTDASgrferGVD 154

                          170       180
                   ....*....|....*....|
gi 31981400    260 FTKAKIVLDIIVTMFSEHCE 279
Cdd:smart00873 155 PELVELALDRAAALLLEICG 174
B3_4 pfam03483
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ...
 117-278 2.83e-19

B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.


Pssm-ID: 427327 [Multi-domain]  Cd Length: 174  Bit Score: 85.29  E-value: 2.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   117 VRPFAVAAVLRNIKFTKDrydSFIELQEKLHQniCRKR---ALV------------AIGTHDLDTLSGPFTytakrpsdi 181
Cdd:pfam03483   1 ACPRYFGRVIRGVKKNRP---SPEWLQRRLRR--AGIRpinNVVditnyvmlelgqPLHAFDLDKIAGDIV--------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   182 kfKPLNKTKEytacELMNIYKTDNHLKhylhiieskPLYPVIYDSNGVVlSMPPIINGNHSKITVNTRNIFIECT----- 256
Cdd:pfam03483  67 --VRLAKGGE----KFTTLDGKERELD---------PGDLVIADDDGPV-ALAGIMGGEESEVTEDTTNIFLESAgfdpv 130

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 31981400   257 ---------------------GTDFTKAKIVLDIIVTMFSEHC 278
Cdd:pfam03483 131 airktarrlglrtdasyrferGVDPELVEAALDRATALLLELC 173
B5 pfam03484
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
 309-374 1.18e-17

tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.


Pssm-ID: 460942 [Multi-domain]  Cd Length: 67  Bit Score: 77.43  E-value: 1.18e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 31981400   309 VRADLINKKVGIRETPANLAKLLTRMCLKSEVIgDGNQIEVEIPPTRADVIHACDIVEDAAIAYGY 374
Cdd:pfam03484   3 LRLDRINRLLGIDLSAEEIVEILERLGFEVEEE-DGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
B5 smart00874
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
 305-374 4.91e-17

tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.


Pssm-ID: 197942 [Multi-domain]  Cd Length: 68  Bit Score: 75.61  E-value: 4.91e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400    305 RKEMVRADLINKKVGIRETPANLAKLLTRMCLKSEVIGDGnqIEVEIPPTRADVIHACDIVEDAAIAYGY 374
Cdd:smart00874   1 RTITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDT--LEVTVPSYRFDILIEADLIEEVARIYGY 68
syfB CHL00192
phenylalanyl-tRNA synthetase beta chain; Provisional
 32-587 9.31e-12

phenylalanyl-tRNA synthetase beta chain; Provisional


Pssm-ID: 214391 [Multi-domain]  Cd Length: 704  Bit Score: 67.81  E-value: 9.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400   32 GLELDEITSEKqiISKEqghgkaqgaSDVVLyKIDVPANRYDLLCLEGLARGLQVF--KERIKAPVYKRVMPKGDIQKLV 109
Cdd:CHL00192  30 GFEVEDILSVK--IGGE---------SDIIL-DISSTANRSDVLSIQGLSREISALfnSDPIKLKYYNPSISWFDKLKNL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  110 ITEETAKVR-PFAVAAVLRNIKFtkdrYDSFIELQEKLhqnicrkralVAIGTHDLDTLSGPFTYTA-KRPSDIKFKPLN 187
Cdd:CHL00192  98 ISNDSSKLNcSMFIAVIIENIEI----KDSPKWLQNRL----------SSSGFKSLNNLTDIQNYIMlETGQPIEIYDLD 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  188 KtkeytacelmnIYKTDNhlKHYLHIIESKPLYP---VIYDS--------------NGVVLSMPPIINGNHSKITVNTRN 250
Cdd:CHL00192 164 K-----------IYSKNT--TSSLALSSKFALQKssfIASNSknielennilvvqaNNVIISIAGIISNEEIICDKNTKS 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  251 IFIEctGTDFTKAKI-----VLDIiVTMFSEHCENQFTV----EAV-EVVS------PNGKSSTFPELPYRKEMVRADLI 314
Cdd:CHL00192 231 ILIE--ASIFDAAVIrkssrKLGL-RTDRSIRYEKSLKNdnllEAYyRLVSllrilnPKLKCKFHFIYKKIKNSSRRIKL 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  315 NKK-------------VGIRETPANLAKLLTRMCLKSEVIGDGNQIEVEIPPTRA-DVIHACDIVEDAAIAYGYNNIQMT 380
Cdd:CHL00192 308 SYKkikdilgpikintNTRYLSPKEITNALKRLNFKITYDSLKLNWEVLIPSYRKdDIVREIDVIEEIARIYGFNNFLSK 387

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  381 LPKTYTIAN-----QFpLNKLTELLRldmaAAGFTEALTFALCSQEDIADklgldisatKAVHISNPKTAEFQVARTTLL 455
Cdd:CHL00192 388 LPNIKFIGRldidyNT-RDKIRSYLR----NLGLTELIHYSLVKQESFSK---------NEIKLKNPLIKDYSTLRSSLL 453

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31981400  456 PGLLKTIAAN-RKMPLPLKLFEISDVVVKDSGKDVGAKnyrHLCAVYYN----KTPGFEIIH--------GLLDRIMQLL 522
Cdd:CHL00192 454 PGLIEAVQENlKQGNSTLEGFEIGHVFNLDSSSIIEET---ELAGGIFGgidiRSSWSEKAQslnwfeakGIIENFFQKL 530

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31981400  523 DVPPgeesggYMIKASAGSA---FFPGRCAEIFV-GGQSIGKLGVLHPDVITKFELTMPCSSLEINIEP 587
Cdd:CHL00192 531 NLPI------YWKKYSDLDEkinFHPYCTSEIFLsNGQKIGIFGQLHPLLANKLNLNTEIYLFEINLDI 593
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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