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Conserved domains on  [gi|164519122|ref|NP_037428|]
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G-protein-signaling modulator 2 [Homo sapiens]

Protein Classification

TPR and TPR_12 domain-containing protein; tetratricopeptide repeat protein( domain architecture ID 11421212)

protein containing domains TPR, TPR_12, and GoLoco; tetratricopeptide repeat (TPR) protein such as kinesin light chain, which mediates the selective binding of kinesin to its cargo

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
65-335 8.93e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 89.30  E-value: 8.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  65 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 144
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 145 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 224
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 225 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 304
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 164519122 305 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 335
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
GoLoco pfam02188
GoLoco motif;
490-511 4.31e-07

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.31e-07
                          10        20
                  ....*....|....*....|..
gi 164519122  490 EGFFDLLSRFQSNRMDDQRCCL 511
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 594-616 2.16e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


:

Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.41  E-value: 2.16e-06
                           10        20
                   ....*....|....*....|...
gi 164519122   594 DEDFFDILVKCQGSRLDDQRCAP 616
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
629-650 4.47e-06

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 4.47e-06
                          10        20
                  ....*....|....*....|..
gi 164519122  629 EDFFSLILRSQGKRMDEQRVLL 650
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
545-566 1.64e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.64e-05
                          10        20
                  ....*....|....*....|..
gi 164519122  545 DEFLDLLASSQSRRLDDQRASF 566
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_7 pfam13176
Tetratricopeptide repeat;
324-359 2.33e-03

Tetratricopeptide repeat;


:

Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 164519122  324 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 359
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
65-335 8.93e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 89.30  E-value: 8.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  65 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 144
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 145 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 224
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 225 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 304
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 164519122 305 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 335
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
TPR_12 pfam13424
Tetratricopeptide repeat;
243-314 3.87e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.55  E-value: 3.87e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164519122  243 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQL--KDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 314
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
490-511 4.31e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.31e-07
                          10        20
                  ....*....|....*....|..
gi 164519122  490 EGFFDLLSRFQSNRMDDQRCCL 511
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 489-511 6.25e-07

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 45.96  E-value: 6.25e-07
                           10        20
                   ....*....|....*....|...
gi 164519122   489 DEGFFDLLSRFQSNRMDDQRCCL 511
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 594-616 2.16e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.41  E-value: 2.16e-06
                           10        20
                   ....*....|....*....|...
gi 164519122   594 DEDFFDILVKCQGSRLDDQRCAP 616
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
629-650 4.47e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 4.47e-06
                          10        20
                  ....*....|....*....|..
gi 164519122  629 EDFFSLILRSQGKRMDEQRVLL 650
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
595-614 4.74e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.18  E-value: 4.74e-06
                          10        20
                  ....*....|....*....|
gi 164519122  595 EDFFDILVKCQGSRLDDQRC 614
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRC 20
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 628-650 8.27e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.87  E-value: 8.27e-06
                           10        20
                   ....*....|....*....|...
gi 164519122   628 DEDFFSLILRSQGKRMDEQRVLL 650
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 88-407 1.56e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.38  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  88 DLTLARTIGDQLGEA-------------KASGNLGNTLKVLGNFDEAivccqrhldisRELNDKV-GEARALYNLGNVYH 153
Cdd:NF040586 407 DYESARDLAERALERwrerlgpddrqtlRLRFHLANALRSLGRYEEA-----------RELDEDTlERQRRVLGLGEDHP 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 154 ----AKGkSFGcpgpQD---VGEFPE---EVRDALQAAVDFYEENlslvtalgDRAAQgRAFGNLGNTHYLLGNFRDAVI 223
Cdd:NF040586 476 htlmTAG-GLG----ADlraLGRFREaleLDEETLERHRRVFGED--------HPRTL-RAANNLAVSLRLLGDYREALE 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 224 AHEQRLLIAKE-FG-DKAAERRAYSNLGNAYIFLGEF-------ETASEYYKKTLLLA------RQLKDRAVeaqSCYSL 288
Cdd:NF040586 542 LDREVLRRRRRvLGpDHPRTLLSANNLARDLRELGRYaealdllEEALERYREVLGGPdhpdtlRAAKSLAV---ALRRA 618

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 289 GntytllqDYEKAidyhlkhLAIAQE----LNDRIGEG----RAC-WSLGNAYTALGNHDQAMHFAEKHLEISREVGdks 359
Cdd:NF040586 619 G-------RLEEA-------LELAEDtyerYRRRFGPDhpdtLAAaLSLANDLRALGDADEARELAREVLDRYRRVL--- 681

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 164519122 360 GE-----LTARLNLSDLQMVLGLSYstnnsimsENTEID-SSLNGVRPKLGRRH 407
Cdd:NF040586 682 GEdhpftLACRNNLAVLLRALGDPE--------EARELAeAALEGLRERLGPDH 727
GoLoco pfam02188
GoLoco motif;
545-566 1.64e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.64e-05
                          10        20
                  ....*....|....*....|..
gi 164519122  545 DEFLDLLASSQSRRLDDQRASF 566
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 544-566 7.49e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.18  E-value: 7.49e-05
                           10        20
                   ....*....|....*....|...
gi 164519122   544 TDEFLDLLASSQSRRLDDQRASF 566
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 282-314 5.20e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 5.20e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 164519122   282 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 314
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_7 pfam13176
Tetratricopeptide repeat;
324-359 2.33e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 164519122  324 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 359
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 323-354 9.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 9.85e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 164519122   323 RACWSLGNAYTALGNHDQAMHFAEKHLEISRE 354
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
65-335 8.93e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 89.30  E-value: 8.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  65 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 144
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 145 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 224
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 225 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 304
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 164519122 305 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 335
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
101-368 2.93e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 87.75  E-value: 2.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 101 EAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQA 180
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR--------------------YEE 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 181 AVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFET 260
Cdd:COG0457   61 ALADYEQ------ALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDE 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 261 ASEYYKKTLLLARQLkdraveAQSCYSLGNTYTLLQDYEKAIDYHLKhlAIAQELNDRIGEGRACWSLGNAYTALGNHDQ 340
Cdd:COG0457  129 AIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALL 200

                        250       260
                 ....*....|....*....|....*...
gi 164519122 341 AMHFAEKHLEISREVGDKSGELTARLNL 368
Cdd:COG0457  201 LALEQALRKKLAILTLAALAELLLLALA 228
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 67-351 2.01e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.00  E-value: 2.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  67 QLGNAYFYLHDYAKALEYhhhdltLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALY 146
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDL------LEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 147 NLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHE 226
Cdd:COG2956   81 ELAQDYLKAGL--------------------LDRAEELLEK------LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 227 QrllIAKEFGDKAaerRAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhl 306
Cdd:COG2956  135 R---LLKLGPENA---HAYCELAELYLEQGDYDEAIEALEK----ALKLDPDCARAL--LLLAELYLEQGDYEEAI---- 198

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 164519122 307 KHLAIAQELNDRIGEGRAcwSLGNAYTALGNHDQAMHFAEKHLEI 351
Cdd:COG2956  199 AALERALEQDPDYLPALP--RLAELYEKLGDPEEALELLRKALEL 241
COG3899 COG3899
Predicted ATPase [General function prediction only];
175-329 3.85e-12

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 69.89  E-value: 3.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  175 RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNF-------RDAVIAHEQRLLIAKEFGDKAAERRAYSN 247
Cdd:COG3899   718 RGAYAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGRFeeaeallERALAARALAALAALRHGNPPASARAYAN 797

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  248 LGnaYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWS 327
Cdd:COG3899   798 LG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAA 875


                  ..
gi 164519122  328 LG 329
Cdd:COG3899   876 AA 877
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 29-350 2.00e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 2.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  29 LEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNL 108
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALLEL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 109 GNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEn 188
Cdd:COG2956   83 AQDYLKAGLLDRAEELLEKLLELDPD------DAEALRLLAEIYEQEGD--------------------WEKAIEVLER- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 189 lslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFgdkaaeRRAYSNLGNAYIFLGEFETASEYYKKT 268
Cdd:COG2956  136 -----LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAELYLEQGDYEEAIAALERA 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 269 LllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIgegracwSLGNAYTALGNHDQAMHFAEKH 348
Cdd:COG2956  205 L----EQDPDYLPAL--PRLAELYEKLGDPEEALELLRKALELDPSDDLLL-------ALADLLERKEGLEAALALLERQ 271


                 ..
gi 164519122 349 LE 350
Cdd:COG2956  272 LR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 56-274 4.48e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.17  E-value: 4.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  56 EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNLGNTLKVLGNFDEAIVCCQRHLDIsrel 135
Cdd:COG3914   72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALAL---- 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 136 ndKVGEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLslvtalgdraaqgRAFGNLGNTHYLL 215
Cdd:COG3914  142 --NPDFAEAYLNLGEALRRLGR-------------LEEAIAALRRALELDPDNA-------------EALNNLGNALQDL 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 164519122 216 GNFRDAVIAHEQRLLIAKEFgdkaaeRRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 274
Cdd:COG3914  194 GRLEEAIAAYRRALELDPDN------ADAHSNLLFALRQACDWEVYDRFEELLAALARG 246
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 175-351 3.87e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 175 RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIF 254
Cdd:COG3914   51 LAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAE------ALFNLGNLLLA 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 255 LGEFETASEYYKKtlllARQLKDRAVEAqsCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDrigegrACWSLGNAYTA 334
Cdd:COG3914  125 LGRLEEALAALRR----ALALNPDFAEA--YLNLGEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQD 192

                        170
                 ....*....|....*..
gi 164519122 335 LGNHDQAMHFAEKHLEI 351
Cdd:COG3914  193 LGRLEEAIAAYRRALEL 209
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 199-352 3.04e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 3.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 199 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDR 278
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE------AFALLGEILLQLGDLDEAIVLLHE----ALELDPD 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164519122 279 AVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndrigEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS 352
Cdd:COG4783   71 EPEAR--LNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR_12 pfam13424
Tetratricopeptide repeat;
243-314 3.87e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.55  E-value: 3.87e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164519122  243 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQL--KDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 314
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 171-376 1.15e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 171 PEEVRDALQAAVDFYEENLSlvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGN 250
Cdd:COG3914   10 AALAAAALLAAAAAAELALA---AELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAAL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 251 AYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELndrigeGRACWSLGN 330
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGE 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 164519122 331 AYTALGNHDQAMHFAEKHLEIsrevgdKSGELTARLNLSDLQMVLG 376
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALEL------DPDNAEALNNLGNALQDLG 194
TPR_12 pfam13424
Tetratricopeptide repeat;
286-354 2.66e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 51.23  E-value: 2.66e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 164519122  286 YSLGNTYTLLQDYEKAIDYHLKHLAIAQEL--NDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISRE 354
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 178-312 3.47e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 3.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 178 LQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGE 257
Cdd:COG3914   94 YEEALALYRR------ALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGR 161

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 164519122 258 FETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIA 312
Cdd:COG3914  162 LEEAIAALRR----ALELDPDNAEAL--NNLGNALQDLGRLEEAIAAYRRALELD 210
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
31-245 8.89e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 8.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  31 GERLCKSGDCRAGVSFFEAAVQVGTEDlktlSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNLGN 110
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALEDYDKALELDPD------DAEALYNLGL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 111 TLKVLGNFDEAIVCCQRHLDISRELndkvgeARALYNLGNVYHAKGKSfgcPGPQDVGEFPEEVRDALQAAVDFYEENLS 190
Cdd:COG0457  119 ALLELGRYDEAIEAYERALELDPDD------ADALYNLGIALEKLGRY---EEALELLEKLEAAALAALLAAALGEAALA 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 164519122 191 LVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAY 245
Cdd:COG0457  190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
COG3899 COG3899
Predicted ATPase [General function prediction only];
78-341 1.23e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 55.25  E-value: 1.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122   78 YAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYhakgk 157
Cdd:COG3899   728 LERALELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLL----- 802

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  158 sfgcpgpqdvgefpeevRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGD 237
Cdd:COG3899   803 -----------------LGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGD 865

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  238 KAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLAR------QLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAI 311
Cdd:COG3899   866 AALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAaalaaaAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAAL 945

                         250       260       270
                  ....*....|....*....|....*....|
gi 164519122  312 AQELNDRIGEGRACWSLGNAYTALGNHDQA 341
Cdd:COG3899   946 AAAAAAAALAAALALAAAAAAAAAAALAAA 975
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 191-304 3.01e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.00  E-value: 3.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 191 LVTALGDRAAQ----GRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYK 266
Cdd:COG4235    2 AIARLRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD------ALLDLAEALLAAGDTEEAEELLE 75

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 164519122 267 KtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDY 304
Cdd:COG4235   76 R----ALALDPDNPEAL--YLLGLAAFQQGDYAEAIAA 107
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 140-314 3.90e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 3.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 140 GEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLslvtalgdraaqgRAFGNLGNTHYLLGNFR 219
Cdd:COG4783    2 ACAEALYALAQALLLAGD-------------YDEAEALLEKALELDPDNP-------------EAFALLGEILLQLGDLD 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 220 DAVIAHEQRLLIAKEfgdkaaERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYE 299
Cdd:COG4783   56 EAIVLLHEALELDPD------EPEARLNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGRPD 123

                        170
                 ....*....|....*
gi 164519122 300 KAIDYHLKHLAIAQE 314
Cdd:COG4783  124 EAIAALEKALELDPD 138
GoLoco pfam02188
GoLoco motif;
490-511 4.31e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.31e-07
                          10        20
                  ....*....|....*....|..
gi 164519122  490 EGFFDLLSRFQSNRMDDQRCCL 511
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
203-274 4.76e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.77  E-value: 4.76e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164519122  203 RAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEF--GDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 274
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 489-511 6.25e-07

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 45.96  E-value: 6.25e-07
                           10        20
                   ....*....|....*....|...
gi 164519122   489 DEGFFDLLSRFQSNRMDDQRCCL 511
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
102-187 8.08e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.00  E-value: 8.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  102 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISREL--NDKVGEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQ 179
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGR-------------YEEALELLE 69


                  ....*...
gi 164519122  180 AAVDFYEE 187
Cdd:pfam13424  70 RALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 165-312 1.33e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.80  E-value: 1.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 165 QDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrA 244
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------L 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164519122 245 YSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIA 312
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEK----ALALSPDNPNAY--SNLAALLLSLGQDDEAKAALQRALGTS 152
TPR_12 pfam13424
Tetratricopeptide repeat;
61-134 2.13e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.84  E-value: 2.13e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 164519122   61 LSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTI--GDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRE 134
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 594-616 2.16e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.41  E-value: 2.16e-06
                           10        20
                   ....*....|....*....|...
gi 164519122   594 DEDFFDILVKCQGSRLDDQRCAP 616
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 26-157 2.50e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 2.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  26 ELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLktlsAIYSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKAS 105
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 164519122 106 GNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGK 157
Cdd:COG4783   76 LNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGR 121
GoLoco pfam02188
GoLoco motif;
629-650 4.47e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 4.47e-06
                          10        20
                  ....*....|....*....|..
gi 164519122  629 EDFFSLILRSQGKRMDEQRVLL 650
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
595-614 4.74e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.18  E-value: 4.74e-06
                          10        20
                  ....*....|....*....|
gi 164519122  595 EDFFDILVKCQGSRLDDQRC 614
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRC 20
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 628-650 8.27e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.87  E-value: 8.27e-06
                           10        20
                   ....*....|....*....|...
gi 164519122   628 DEDFFSLILRSQGKRMDEQRVLL 650
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
251-354 1.05e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 1.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 251 AYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYEKAIDYHLkhlaiAQELNDRIGEgrACWSLGN 330
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAE--ALLNLAE 67

                         90       100
                 ....*....|....*....|....
gi 164519122 331 AYTALGNHDQAMHFAEKHLEISRE 354
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 243-352 1.12e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 243 RAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhlKHLAIAQELNDRigEG 322
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEK----ALRLDPDNADAL--LDLAEALLAAGDTEEAE----ELLERALALDPD--NP 85

                         90       100       110
                 ....*....|....*....|....*....|
gi 164519122 323 RACWSLGNAYTALGNHDQAMHFAEKHLEIS 352
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 88-407 1.56e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.38  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  88 DLTLARTIGDQLGEA-------------KASGNLGNTLKVLGNFDEAivccqrhldisRELNDKV-GEARALYNLGNVYH 153
Cdd:NF040586 407 DYESARDLAERALERwrerlgpddrqtlRLRFHLANALRSLGRYEEA-----------RELDEDTlERQRRVLGLGEDHP 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 154 ----AKGkSFGcpgpQD---VGEFPE---EVRDALQAAVDFYEENlslvtalgDRAAQgRAFGNLGNTHYLLGNFRDAVI 223
Cdd:NF040586 476 htlmTAG-GLG----ADlraLGRFREaleLDEETLERHRRVFGED--------HPRTL-RAANNLAVSLRLLGDYREALE 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 224 AHEQRLLIAKE-FG-DKAAERRAYSNLGNAYIFLGEF-------ETASEYYKKTLLLA------RQLKDRAVeaqSCYSL 288
Cdd:NF040586 542 LDREVLRRRRRvLGpDHPRTLLSANNLARDLRELGRYaealdllEEALERYREVLGGPdhpdtlRAAKSLAV---ALRRA 618

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 289 GntytllqDYEKAidyhlkhLAIAQE----LNDRIGEG----RAC-WSLGNAYTALGNHDQAMHFAEKHLEISREVGdks 359
Cdd:NF040586 619 G-------RLEEA-------LELAEDtyerYRRRFGPDhpdtLAAaLSLANDLRALGDADEARELAREVLDRYRRVL--- 681

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 164519122 360 GE-----LTARLNLSDLQMVLGLSYstnnsimsENTEID-SSLNGVRPKLGRRH 407
Cdd:NF040586 682 GEdhpftLACRNNLAVLLRALGDPE--------EARELAeAALEGLRERLGPDH 727
GoLoco pfam02188
GoLoco motif;
545-566 1.64e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.64e-05
                          10        20
                  ....*....|....*....|..
gi 164519122  545 DEFLDLLASSQSRRLDDQRASF 566
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_7 pfam13176
Tetratricopeptide repeat;
284-318 1.96e-05

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 41.76  E-value: 1.96e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 164519122  284 SCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDR 318
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-352 2.91e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 2.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 248 LGNAYIFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndrigEGRACWS 327
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEAL----ELDPETVEAH--LALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALLE 81

                         90       100
                 ....*....|....*....|....*
gi 164519122 328 LGNAYTALGNHDQAMHFAEKHLEIS 352
Cdd:COG2956   82 LAQDYLKAGLLDRAEELLEKLLELD 106
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
173-352 3.06e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.68  E-value: 3.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 173 EVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAaerRAYSNLGNAY 252
Cdd:COG4785    7 ALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLA---QLYYERGVAY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 253 IFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYhlkhLAIAQELNDRIGEgrACWSLGNAY 332
Cdd:COG4785   84 DSLGDYDLAIADFDQAL----ELDPDLAEAY--NNRGLAYLLLGDYDAALED----FDRALELDPDYAY--AYLNRGIAL 151

                        170       180
                 ....*....|....*....|
gi 164519122 333 TALGNHDQAMHFAEKHLEIS 352
Cdd:COG4785  152 YYLGRYELAIADLEKALELD 171
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
141-324 4.62e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 4.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 141 EARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEenlslvTALGDRAAQGRAFGNLGNTHYLLGNFRD 220
Cdd:COG4785   72 LAQLYYERGVAYDSLGD--------------------YDLAIADFD------QALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 221 AVIAheqrlliakeFgDKAAERR-----AYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYslgntytLL 295
Cdd:COG4785  126 ALED----------F-DRALELDpdyayAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAE-------RK 187

                        170       180
                 ....*....|....*....|....*....
gi 164519122 296 QDYEKAIDYHLKHLAIAQELNDRIGEGRA 324
Cdd:COG4785  188 LDPEKALALLLEDWATAYLLQGDTEEARE 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 239-376 5.70e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 5.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 239 AAERRAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndr 318
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEK----ALELDPDNPEAF--ALLGEILLQLGDLDEAIVLLHEALELDPD---- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 164519122 319 igEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDksgeltARLNLSDLQMVLG 376
Cdd:COG4783   71 --EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALG 120
TPR_12 pfam13424
Tetratricopeptide repeat;
142-234 7.03e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 7.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  142 ARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEENLSLVTAL--GDRAAQGRAFGNLGNTHYLLGNFR 219
Cdd:pfam13424   3 ATALNNLAAVLRRLGR--------------------YDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYE 62

                          90
                  ....*....|....*
gi 164519122  220 DAVIAHEQRLLIAKE 234
Cdd:pfam13424  63 EALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 194-352 7.48e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 7.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 194 ALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKtlllAR 273
Cdd:COG5010    6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQ----AL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164519122 274 QLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhlKHLAIAQELNDriGEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS 352
Cdd:COG5010   82 QLDPNNPELY--YNLALLYSRSGDKDEAK----EYYEKALALSP--DNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 544-566 7.49e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.18  E-value: 7.49e-05
                           10        20
                   ....*....|....*....|...
gi 164519122   544 TDEFLDLLASSQSRRLDDQRASF 566
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
172-318 8.30e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.52  E-value: 8.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 172 EEVRDALQAAVDFYEENLSLVTALGDRAaqgRAFGNLGNTHYLLGNFRDAVIAHEQRLliaKEFGDKAaerRAYSNLGNA 251
Cdd:COG4785   46 LALAAAALAAAALAAERIDRALALPDLA---QLYYERGVAYDSLGDYDLAIADFDQAL---ELDPDLA---EAYNNRGLA 116

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 164519122 252 YIFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDR 318
Cdd:COG4785  117 YLLLGDYDAALEDFDRAL----ELDPDYAYAY--LNRGIALYYLGRYELAIADLEKALELDPNDPER 177
COG3899 COG3899
Predicted ATPase [General function prediction only];
25-366 2.18e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.85  E-value: 2.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122   25 LELALE-GERLCKSGDCRAGVSFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIG 96
Cdd:COG3899   745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122   97 DQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYnlgnvyhakgkSFGCPGPQDVGEFPEEVRD 176
Cdd:COG3899   825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALA-----------AAAAAAAAAAALAAAAAAA 893

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  177 ALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEfgdkAAERRAYSNLGNAYIFLG 256
Cdd:COG3899   894 ARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAA----AALAAALALAAAAAAAAA 969

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  257 EFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALG 336
Cdd:COG3899   970 AALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAAL 1049

                         330       340       350
                  ....*....|....*....|....*....|
gi 164519122  337 NHDQAMHFAEKHLEISREVGDKSGELTARL 366
Cdd:COG3899  1050 AAAAAAAAAAAALAAAAALLAAAAAAAAAA 1079
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 212-304 2.56e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 2.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 212 HYLLGNFRDAVIAHEQrllIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKtllLARQLKDRAVEAQSCYSLGNT 291
Cdd:COG1729    3 LLKAGDYDEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGLS 76

                         90
                 ....*....|...
gi 164519122 292 YTLLQDYEKAIDY 304
Cdd:COG1729   77 YLELGDYDKARAT 89
TPR_1 pfam00515
Tetratricopeptide repeat;
243-274 2.93e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 2.93e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 164519122  243 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 274
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 179-267 3.88e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 3.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 179 QAAVDFYEEnlsLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQrllIAKEFGDKAAERRAYSNLGNAYIFLGEF 258
Cdd:COG1729   10 DEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGLSYLELGDY 83


                 ....*....
gi 164519122 259 ETASEYYKK 267
Cdd:COG1729   84 DKARATLEE 92
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 57-233 3.97e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 3.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  57 DLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISREln 136
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN-- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 137 dkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLG 216
Cdd:COG5010   87 ----NPELYYNLALLYSRSGD--------------------KDEAKEYYEK------ALALSPDNPNAYSNLAALLLSLG 136

                        170
                 ....*....|....*..
gi 164519122 217 NFRDAVIAHEQRLLIAK 233
Cdd:COG5010  137 QDDEAKAALQRALGTSP 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 251-341 4.85e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 4.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 251 AYIFLGEFETASEYYKKtllLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKhlaIAQELNDRIGEGRACWSLGN 330
Cdd:COG1729    2 ALLKAGDYDEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                         90
                 ....*....|.
gi 164519122 331 AYTALGNHDQA 341
Cdd:COG1729   76 SYLELGDYDKA 86
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 282-314 5.20e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 5.20e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 164519122   282 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 314
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
102-131 6.19e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 6.19e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 164519122  102 AKASGNLGNTLKVLGNFDEAIVCCQRHLDI 131
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 243-274 6.52e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.52e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 164519122   243 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 274
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 102-134 1.11e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.11e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 164519122   102 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRE 134
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
61-269 1.19e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.05  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  61 LSAIYSQLGNAYFYLHDYAKALEyhhhDLTLArtIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLdisrELNDKvg 140
Cdd:COG4785   72 LAQLYYERGVAYDSLGDYDLAIA----DFDQA--LELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL----ELDPD-- 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 141 EARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENlslvtalgdraaqgrafgnlgnthyllgnfrd 220
Cdd:COG4785  140 YAYAYLNRGIALYYLGR-------------YELAIADLEKALELDPND-------------------------------- 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 164519122 221 aVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 269
Cdd:COG4785  175 -PERALWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLAL 222
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 142-283 1.32e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 142 ARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLSlvtalgdraaqgrAFGNLGNTHYLLGNFRDA 221
Cdd:COG4235   17 AEGWLLLGRAYLRLGR-------------YDEALAAYEKALRLDPDNAD-------------ALLDLAEALLAAGDTEEA 70

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 164519122 222 VIAHEQRLLIAKEFGdkaaerRAYSNLGNAYIFLGEFETASEYYKKTL-LLARQLKDRAVEAQ 283
Cdd:COG4235   71 EELLERALALDPDNP------EALYLLGLAAFQQGDYAEAIAAWQKLLaLLPADAPARLLEAS 127
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 107-230 1.45e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 107 NLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYE 186
Cdd:COG4235   22 LLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGD-------------TEEAEELLERALALDP 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 164519122 187 ENLslvtalgdraaqgRAFGNLGNTHYLLGNFRDAvIAHEQRLL 230
Cdd:COG4235   83 DNP-------------EALYLLGLAAFQQGDYAEA-IAAWQKLL 112
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
212-315 2.24e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 212 HYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKktlllARQLKDRAVEAQscYSLGNT 291
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNAD------ALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAEAL--LNLAEL 68

                         90       100
                 ....*....|....*....|....
gi 164519122 292 YTLLQDYEKAIDYHLKHLAIAQEL 315
Cdd:COG3063   69 LLELGDYDEALAYLERALELDPSA 92
TPR_7 pfam13176
Tetratricopeptide repeat;
244-279 2.26e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 164519122  244 AYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 279
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_7 pfam13176
Tetratricopeptide repeat;
324-359 2.33e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 164519122  324 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 359
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_11 pfam13414
TPR repeat;
109-156 2.87e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.91  E-value: 2.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 164519122  109 GNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARALYNLGNVYHAKG 156
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDN------PEAYYNLGLAYYKLG 42
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
71-157 3.03e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 3.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  71 AYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVcCQRHLDISRElndkvgEARALYNLGN 150
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDP------DNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN------NAEALLNLAE 67


                 ....*..
gi 164519122 151 VYHAKGK 157
Cdd:COG3063   68 LLLELGD 74
TPR COG0790
TPR repeat [General function prediction only];
70-312 3.69e-03

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 39.53  E-value: 3.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122  70 NAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLG----NTLKVLGNFDEAIVCCQRhldiSRELndkvGEARAL 145
Cdd:COG0790   31 AAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGlmyaEGRGVPKDYEKALEWFEK----AAEQ----GDAEAQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 146 YNLGNVYHakgksFGCPGPQDvgefpeevrdaLQAAVDFYEEnlslVTALGDRAAQgrafgnlgnthYLLGNFRDAVIAH 225
Cdd:COG0790  103 YNLGLMYE-----EGLGVPQD-----------YAKALEWYEK----AAEQGDADAQ-----------YNLGLLYLNGEGV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 226 EQRLLIAKEFGDKAAER---RAYSNLGNAYiFLGE-----FETASEYYKKtlllARQLKDraveAQSCYSLGNTYT---- 293
Cdd:COG0790  152 PKDPAKAAEWYRKAAEQgdaDAQYNLGVLY-ENGRgvpkdPAKALEWYRK----AAEQGD----ADAQYNLGRLYLngeg 222

                        250
                 ....*....|....*....
gi 164519122 294 LLQDYEKAIDYHLKHLAIA 312
Cdd:COG0790  223 VEKDLEKALRWLRKAAEQA 241
TPR_1 pfam00515
Tetratricopeptide repeat;
282-314 3.78e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 3.78e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 164519122  282 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 314
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
178-275 5.19e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 5.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164519122 178 LQAAVDFYEENLSLvtalgdRAAQGRAFGNLGNTHYLLGNFRDAvIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGE 257
Cdd:COG3063    8 LEEAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAE------ALLNLAELLLELGD 74

                         90
                 ....*....|....*...
gi 164519122 258 FETASEYYKKTLLLARQL 275
Cdd:COG3063   75 YDEALAYLERALELDPSA 92
TPR_8 pfam13181
Tetratricopeptide repeat;
243-267 6.42e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 6.42e-03
                          10        20
                  ....*....|....*....|....*
gi 164519122  243 RAYSNLGNAYIFLGEFETASEYYKK 267
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEK 26
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 64-94 6.98e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 6.98e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 164519122    64 IYSQLGNAYFYLHDYAKALEYHHHDLTLART 94
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 323-354 9.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 9.85e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 164519122   323 RACWSLGNAYTALGNHDQAMHFAEKHLEISRE 354
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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