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Conserved domains on  [gi|166197668|ref|NP_055022|]
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T-cell surface glycoprotein CD5 isoform 1 precursor [Homo sapiens]

Protein Classification

scavenger receptor cysteine-rich domain-containing protein( domain architecture ID 10640959)

scavenger receptor cysteine-rich (SRCR) domain-containing protein os a member of the group B scavenger receptor cysteine-rich family (SRCR-SF), composed of tandem-repeats of the SRCR domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 36-133 6.42e-16

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 73.14  E-value: 6.42e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668    36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWgrsskqweDPSQASKVCQRLNCGVPLSL--GPFLVTYTPQ---SSIICYGQ 110
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSAsgSAYFGPGSGPiwlDNVRCSGT 73

                           90       100
                   ....*....|....*....|....*...
gi 166197668   111 LGSFSNCSHS--RNDMCHS---LGLTCL 133
Cdd:smart00202  74 EASLSDCPHSgwGSHNCSHgedAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-368 1.43e-06

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 46.57  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668   277 RLVGGSSICEGTVEVRQGAQWAALCDSSsarsslrWEE-----VCREQQCGSVNSYRVLDAGDPTSRGLFCPH------- 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGSAYFGPGSGPIWLDNvrcsgte 74

                           90       100
                   ....*....|....*....|....*...
gi 166197668   345 QKLSQC-HELWERNSyCKK---VFVTCQ 368
Cdd:smart00202  75 ASLSDCpHSGWGSHN-CSHgedAGVVCS 101
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 36-133 6.42e-16

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 73.14  E-value: 6.42e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668    36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWgrsskqweDPSQASKVCQRLNCGVPLSL--GPFLVTYTPQ---SSIICYGQ 110
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSAsgSAYFGPGSGPiwlDNVRCSGT 73

                           90       100
                   ....*....|....*....|....*...
gi 166197668   111 LGSFSNCSHS--RNDMCHS---LGLTCL 133
Cdd:smart00202  74 EASLSDCPHSgwGSHNCSHgedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 40-132 2.17e-08

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 51.61  E-value: 2.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668   40 SNSKCQGQLEVYLKDGWHMVCSQSWgrsskqweDPSQASKVCQRLNCGVPLSLGPFLVTYTP-------QSSIICYGQLG 112
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGW--------DLRDAHVVCRQLGCGGAVSAPSGCSYFGPgstgpiwLDDVRCSGNET 72

                          90       100
                  ....*....|....*....|....*
gi 166197668  113 SFSNCSHS--RNDMCHS---LGLTC 132
Cdd:pfam00530  73 SLWQCPHRpwGNHNCSHsedAGVIC 97
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-368 1.43e-06

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 46.57  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668   277 RLVGGSSICEGTVEVRQGAQWAALCDSSsarsslrWEE-----VCREQQCGSVNSYRVLDAGDPTSRGLFCPH------- 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGSAYFGPGSGPIWLDNvrcsgte 74

                           90       100
                   ....*....|....*....|....*...
gi 166197668   345 QKLSQC-HELWERNSyCKK---VFVTCQ 368
Cdd:smart00202  75 ASLSDCpHSGWGSHN-CSHgedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 281-324 3.53e-04

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 39.67  E-value: 3.53e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 166197668  281 GSSICEGTVEVRQGAQWAALCDSSsarsslrWEE-----VCREQQCGSV 324
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDG-------WDLrdahvVCRQLGCGGA 42
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 36-133 6.42e-16

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 73.14  E-value: 6.42e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668    36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWgrsskqweDPSQASKVCQRLNCGVPLSL--GPFLVTYTPQ---SSIICYGQ 110
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSAsgSAYFGPGSGPiwlDNVRCSGT 73

                           90       100
                   ....*....|....*....|....*...
gi 166197668   111 LGSFSNCSHS--RNDMCHS---LGLTCL 133
Cdd:smart00202  74 EASLSDCPHSgwGSHNCSHgedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 40-132 2.17e-08

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 51.61  E-value: 2.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668   40 SNSKCQGQLEVYLKDGWHMVCSQSWgrsskqweDPSQASKVCQRLNCGVPLSLGPFLVTYTP-------QSSIICYGQLG 112
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGW--------DLRDAHVVCRQLGCGGAVSAPSGCSYFGPgstgpiwLDDVRCSGNET 72

                          90       100
                  ....*....|....*....|....*
gi 166197668  113 SFSNCSHS--RNDMCHS---LGLTC 132
Cdd:pfam00530  73 SLWQCPHRpwGNHNCSHsedAGVIC 97
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-368 1.43e-06

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 46.57  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166197668   277 RLVGGSSICEGTVEVRQGAQWAALCDSSsarsslrWEE-----VCREQQCGSVNSYRVLDAGDPTSRGLFCPH------- 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGSAYFGPGSGPIWLDNvrcsgte 74

                           90       100
                   ....*....|....*....|....*...
gi 166197668   345 QKLSQC-HELWERNSyCKK---VFVTCQ 368
Cdd:smart00202  75 ASLSDCpHSGWGSHN-CSHgedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 281-324 3.53e-04

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 39.67  E-value: 3.53e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 166197668  281 GSSICEGTVEVRQGAQWAALCDSSsarsslrWEE-----VCREQQCGSV 324
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDG-------WDLrdahvVCRQLGCGGA 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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