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Y-box-binding protein 2 [Homo sapiens]
cold shock domain-containing protein( domain architecture ID 10448154)
cold shock domain-containing protein similar to mammalian Y-box-binding proteins, which are DNA- and RNA-binding proteins involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation
List of domain hits
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Name | Accession | Description | Interval | E-value | ||
CSD | pfam00313 | 'Cold-shock' DNA-binding domain; |
94-163 | 6.73e-27 | ||
'Cold-shock' DNA-binding domain; : Pssm-ID: 278729 Cd Length: 66 Bit Score: 101.16 E-value: 6.73e-27
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PRK12323 super family | cl46901 | DNA polymerase III subunit gamma/tau; |
304-352 | 8.75e-04 | ||
DNA polymerase III subunit gamma/tau; The actual alignment was detected with superfamily member PRK14965: Pssm-ID: 481241 [Multi-domain] Cd Length: 576 Bit Score: 41.27 E-value: 8.75e-04
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Name | Accession | Description | Interval | E-value | ||
CSD | pfam00313 | 'Cold-shock' DNA-binding domain; |
94-163 | 6.73e-27 | ||
'Cold-shock' DNA-binding domain; Pssm-ID: 278729 Cd Length: 66 Bit Score: 101.16 E-value: 6.73e-27
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CSP_CDS | cd04458 | Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in ... |
96-162 | 1.12e-23 | ||
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription. Pssm-ID: 239905 Cd Length: 65 Bit Score: 92.64 E-value: 1.12e-23
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CspC | COG1278 | Cold shock protein, CspA family [Transcription]; |
96-161 | 6.90e-20 | ||
Cold shock protein, CspA family [Transcription]; Pssm-ID: 440889 Cd Length: 67 Bit Score: 82.55 E-value: 6.90e-20
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CSP | smart00357 | Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria ... |
96-163 | 5.93e-16 | ||
Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. Pssm-ID: 214633 [Multi-domain] Cd Length: 64 Bit Score: 71.48 E-value: 5.93e-16
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cspE | PRK09507 | cold shock-like protein CspE; |
93-161 | 5.17e-15 | ||
cold shock-like protein CspE; Pssm-ID: 169931 Cd Length: 69 Bit Score: 69.30 E-value: 5.17e-15
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PRK14965 | PRK14965 | DNA polymerase III subunits gamma and tau; Provisional |
304-352 | 8.75e-04 | ||
DNA polymerase III subunits gamma and tau; Provisional Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 41.27 E-value: 8.75e-04
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Name | Accession | Description | Interval | E-value | ||
CSD | pfam00313 | 'Cold-shock' DNA-binding domain; |
94-163 | 6.73e-27 | ||
'Cold-shock' DNA-binding domain; Pssm-ID: 278729 Cd Length: 66 Bit Score: 101.16 E-value: 6.73e-27
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CSP_CDS | cd04458 | Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in ... |
96-162 | 1.12e-23 | ||
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription. Pssm-ID: 239905 Cd Length: 65 Bit Score: 92.64 E-value: 1.12e-23
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CspC | COG1278 | Cold shock protein, CspA family [Transcription]; |
96-161 | 6.90e-20 | ||
Cold shock protein, CspA family [Transcription]; Pssm-ID: 440889 Cd Length: 67 Bit Score: 82.55 E-value: 6.90e-20
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CSP | smart00357 | Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria ... |
96-163 | 5.93e-16 | ||
Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. Pssm-ID: 214633 [Multi-domain] Cd Length: 64 Bit Score: 71.48 E-value: 5.93e-16
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cspE | PRK09507 | cold shock-like protein CspE; |
93-161 | 5.17e-15 | ||
cold shock-like protein CspE; Pssm-ID: 169931 Cd Length: 69 Bit Score: 69.30 E-value: 5.17e-15
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PRK10354 | PRK10354 | RNA chaperone/antiterminator CspA; |
93-161 | 6.06e-14 | ||
RNA chaperone/antiterminator CspA; Pssm-ID: 182402 Cd Length: 70 Bit Score: 66.15 E-value: 6.06e-14
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PRK09890 | PRK09890 | cold shock protein CspG; Provisional |
93-160 | 2.54e-13 | ||
cold shock protein CspG; Provisional Pssm-ID: 77467 Cd Length: 70 Bit Score: 64.40 E-value: 2.54e-13
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PRK10943 | PRK10943 | cold shock-like protein CspC; Provisional |
93-161 | 1.91e-12 | ||
cold shock-like protein CspC; Provisional Pssm-ID: 170841 Cd Length: 69 Bit Score: 62.01 E-value: 1.91e-12
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PRK09937 | PRK09937 | cold shock-like protein CspD; |
96-169 | 1.18e-09 | ||
cold shock-like protein CspD; Pssm-ID: 77494 Cd Length: 74 Bit Score: 54.35 E-value: 1.18e-09
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PRK14998 | PRK14998 | cold shock-like protein CspD; Provisional |
95-158 | 2.38e-08 | ||
cold shock-like protein CspD; Provisional Pssm-ID: 184960 Cd Length: 73 Bit Score: 50.43 E-value: 2.38e-08
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PRK14965 | PRK14965 | DNA polymerase III subunits gamma and tau; Provisional |
304-352 | 8.75e-04 | ||
DNA polymerase III subunits gamma and tau; Provisional Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 41.27 E-value: 8.75e-04
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Blast search parameters | ||||
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