NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|7706349|ref|NP_057155|]
View 

small ribosomal subunit protein mS33 [Homo sapiens]

Protein Classification

mS33 family mitochondrion-specific ribosomal protein( domain architecture ID 10550643)

mS33 family mitochondrion-specific ribosomal protein is a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MRP-S33 pfam08293
Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ...
 6-91 3.76e-23

Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ribosomal subunit S27 in prokaryotes and to subunit S33 in humans. It is a small 106 residue protein.The evolutionary history of the mitoribosomal proteome that is encoded by a diverse subset of eukaryotic genomes, reveals an ancestral ribosome of alpha-proteobacterial descent that more than doubled its protein content in most eukaryotic lineages. Several new MRPs have originated via duplication of existing MRPs as well as by recruitment from outside of the mitoribosomal proteome.


:

Pssm-ID: 462417  Cd Length: 87  Bit Score: 84.87  E-value: 3.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7706349      6 EYAFRMSRLSARLFGEVTRPTNS-KSMKVVKLFSELPLakkkeTYDWYPNHHTYAELMQTLRFLGLYRDEHQDFMDEQKR 84
Cdd:pfam08293   1 ARLLRLARLSARIFGTVYNPETVrTGNKVLRQRLKGPA-----LASYYPRHVTFKDLKKLLRELGLFRDEHEDFRLEMVR 75


                  ....*..
gi 7706349     85 LKKLRGK 91
Cdd:pfam08293  76 LRKLRGK 82
 
Name Accession Description Interval E-value
MRP-S33 pfam08293
Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ...
 6-91 3.76e-23

Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ribosomal subunit S27 in prokaryotes and to subunit S33 in humans. It is a small 106 residue protein.The evolutionary history of the mitoribosomal proteome that is encoded by a diverse subset of eukaryotic genomes, reveals an ancestral ribosome of alpha-proteobacterial descent that more than doubled its protein content in most eukaryotic lineages. Several new MRPs have originated via duplication of existing MRPs as well as by recruitment from outside of the mitoribosomal proteome.


Pssm-ID: 462417  Cd Length: 87  Bit Score: 84.87  E-value: 3.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7706349      6 EYAFRMSRLSARLFGEVTRPTNS-KSMKVVKLFSELPLakkkeTYDWYPNHHTYAELMQTLRFLGLYRDEHQDFMDEQKR 84
Cdd:pfam08293   1 ARLLRLARLSARIFGTVYNPETVrTGNKVLRQRLKGPA-----LASYYPRHVTFKDLKKLLRELGLFRDEHEDFRLEMVR 75


                  ....*..
gi 7706349     85 LKKLRGK 91
Cdd:pfam08293  76 LRKLRGK 82
 
Name Accession Description Interval E-value
MRP-S33 pfam08293
Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ...
 6-91 3.76e-23

Mitochondrial ribosomal subunit S27; This family of proteins corresponds to mitochondrial ribosomal subunit S27 in prokaryotes and to subunit S33 in humans. It is a small 106 residue protein.The evolutionary history of the mitoribosomal proteome that is encoded by a diverse subset of eukaryotic genomes, reveals an ancestral ribosome of alpha-proteobacterial descent that more than doubled its protein content in most eukaryotic lineages. Several new MRPs have originated via duplication of existing MRPs as well as by recruitment from outside of the mitoribosomal proteome.


Pssm-ID: 462417  Cd Length: 87  Bit Score: 84.87  E-value: 3.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7706349      6 EYAFRMSRLSARLFGEVTRPTNS-KSMKVVKLFSELPLakkkeTYDWYPNHHTYAELMQTLRFLGLYRDEHQDFMDEQKR 84
Cdd:pfam08293   1 ARLLRLARLSARIFGTVYNPETVrTGNKVLRQRLKGPA-----LASYYPRHVTFKDLKKLLRELGLFRDEHEDFRLEMVR 75


                  ....*..
gi 7706349     85 LKKLRGK 91
Cdd:pfam08293  76 LRKLRGK 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH