NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|154426300|ref|NP_060292|]
View 

KAT8 regulatory NSL complex subunit 2 [Homo sapiens]

Protein Classification

zf-C3Hc3H domain-containing protein( domain architecture ID 10620855)

zf-C3Hc3H domain-containing protein may be a DNA-binding protein and is similar to human KAT8 regulatory NSL complex subunit 2 that, as part of the NSL complex, is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 308-364 1.02e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 77.00  E-value: 1.02e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 154426300  308 DVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEV--PCNKPVPVSLSEDPCCPLHF 364
Cdd:pfam13891   4 GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnkRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 28-91 1.35e-16

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 73.92  E-value: 1.35e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 154426300   28 CAFThRPCSHPRLEGQEFCIKHILEDKN-APFKQCSYISTKNgKRCPNAAPKPEKKDgvSFCAEH 91
Cdd:pfam13891   1 CSYG-VGCKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGN-KRCGNPVLKSDVPS--PLCPEH 61
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 308-364 1.02e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 77.00  E-value: 1.02e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 154426300  308 DVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEV--PCNKPVPVSLSEDPCCPLHF 364
Cdd:pfam13891   4 GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnkRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 28-91 1.35e-16

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 73.92  E-value: 1.35e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 154426300   28 CAFThRPCSHPRLEGQEFCIKHILEDKN-APFKQCSYISTKNgKRCPNAAPKPEKKDgvSFCAEH 91
Cdd:pfam13891   1 CSYG-VGCKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGN-KRCGNPVLKSDVPS--PLCPEH 61
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 308-364 1.02e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 77.00  E-value: 1.02e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 154426300  308 DVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEV--PCNKPVPVSLSEDPCCPLHF 364
Cdd:pfam13891   4 GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGnkRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 28-91 1.35e-16

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 73.92  E-value: 1.35e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 154426300   28 CAFThRPCSHPRLEGQEFCIKHILEDKN-APFKQCSYISTKNgKRCPNAAPKPEKKDgvSFCAEH 91
Cdd:pfam13891   1 CSYG-VGCKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGN-KRCGNPVLKSDVPS--PLCPEH 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH