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Conserved domains on  [gi|222831590|ref|NP_060762|]
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glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial [Homo sapiens]

Protein Classification

amidase( domain architecture ID 10000643)

amidase catalyzes the hydrolysis of a monocarboxylic acid amide to form a monocarboxylate and ammonia; similar to aspartyl/glutamyl-tRNA synthase subunit A (GatA), which is part of a heterotrimeric complex that forms correctly charged Gln-tRNA(Gln) or Asn-tRNA(Asn) through the transamidation of misacylated Glu-tRNA(Gln) or Asp-tRNA(Asn)

CATH:  3.90.1300.10
Gene Ontology:  GO:0003824
SCOP:  3001251|4002446

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 6.10e-165

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


:

Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 475.80  E-value: 6.10e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   1 MLGRSLREVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqNPHse 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 240 AAIVLGALAGPDPRDSTTVHEPInKPFMLPSLADVSKLCIGIPKEYLVPE-LSSEVQSLWSKAADLFESEGAKVIEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdidvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 222831590 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 6.10e-165

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 475.80  E-value: 6.10e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   1 MLGRSLREVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqNPHse 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 240 AAIVLGALAGPDPRDSTTVHEPInKPFMLPSLADVSKLCIGIPKEYLVPE-LSSEVQSLWSKAADLFESEGAKVIEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdidvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 222831590 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 11-496 2.80e-160

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 463.73  E-value: 2.80e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   11 AALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRykngqSLGDLDGIPIAVKDNFSTSGIETTCA 89
Cdd:TIGR00132   3 QLLKKKEISIKEVLEASLDRIEANKdKINAFLEVTVEKALKQAKKLDKA-----ILTPLAGIPIAVKDNISTKGIVTTCA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqnphseNEDsdwLITG 169
Cdd:TIGR00132  78 SKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPW-----------------NLD---RVPG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  170 GSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAG 249
Cdd:TIGR00132 138 GSSGGSAAAVAADLAPFSLGSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISG 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  250 PDPRDSTTVHEPInkPFMLPSLADVSK-LCIGIPKEYLvPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYH 328
Cdd:TIGR00132 218 HDKRDSTSAKVPD--PEFFEELKKDLKgLKVGVVKEFS-EEMDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYY 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  329 VLCTSEVASNMARFDGLQYGHRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFV 408
Cdd:TIGR00132 295 IISPSEASSNLARYDGIRYGYRIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFL 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  409 NAFnSGVDVLLTPTTlseavPYLEFI---KEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQ 485
Cdd:TIGR00132 375 KLF-EEVDVIVSPTA-----PTLPFKigeKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKEKGLPIGLQIIGKCFDDK 448

                         490
                  ....*....|.
gi 222831590  486 QLLTVAKWFEK 496
Cdd:TIGR00132 449 TLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
37-488 3.24e-135

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 398.98  E-value: 3.24e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   37 LNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLM 116
Cdd:pfam01425  17 LNAFVTVFFDEALAQAAAADKQRAAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPYDATVVERLRKAGAVIL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  117 GKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqnphseneDSDW-----------LItggssggsaaavSAFTCY 185
Cdd:pfam01425  97 GKTNMDEFAMGSSTENSVFGPTRNPW-------------------DLSRtpggssggsaaAV------------AAGLVP 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  186 AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPInKP 265
Cdd:pfam01425 146 LAIGTDTGGSIRIPASFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPV-PD 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  266 FMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGl 345
Cdd:pfam01425 225 YAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDG- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  346 qyghRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLS 425
Cdd:pfam01425 304 ----VPSGPDDLSELYPRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEE-LDVLLSPTAPT 378

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 222831590  426 EAVPYLEFikEDNRTRSAQDDIFTQA---VNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLL 488
Cdd:pfam01425 379 PAPRLGEP--DDSPLVMYNLDDFTAGvvpVNLAGLPAISLPAGFTADGLPVGVQIIGKPGDEETLL 442
PRK07139 PRK07139
amidase; Provisional
 75-496 1.04e-76

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 248.42  E-value: 1.04e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  75 VKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQ 154
Cdd:PRK07139  44 IKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKNPLDSSKLVGGSSSG 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 155 NPHSENEDSDWlitggssggsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK07139 124 SAATFNKNISF---------------------AIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFT 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 235 RCVDDAAIVLGALAGPDPRDSTTVHEPIN-----KPFMLPSLaDVSKlcigipkeylvpELSSEVQSLWSKAADLFESEG 309
Cdd:PRK07139 183 HNVNDAIILSKVLFGKDENDLTSVDVKINnvkktKPKKVAYL-DCFK------------ELEEYVAKKYKKLINILKSEN 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 310 AKVIEVSLPH-------TSYSIVCYhvlctSEVASNMARFDGLQYGHRCDIDvSTEAMYAATRREGFNDVVRGRILSGNF 382
Cdd:PRK07139 250 IEVEKIKIDEkllkaikPVYKIISY-----SEASSNLANLNGIAFGNREKGS-SWEEIMINTRSEGFGKMVQKRLILGSY 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 383 FLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAvPYLEFIKEDNrtRSAQDDIFTQAvNMAGLPAVSI 462
Cdd:PRK07139 324 FLEEENQEKYFLKAKKVRRVIKNYYESIHNK-FDIVIYPAYADIA-PDIDENENKS--DNYMDYILTIS-NLVGNPSLSI 398

                        410       420       430
                 ....*....|....*....|....*....|....
gi 222831590 463 PVAlSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07139 399 PLG-KYNNLPFNLAIDSKIYDDEKLLSYSLYIEE 431
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 1-496 6.10e-165

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 475.80  E-value: 6.10e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   1 MLGRSLREVSAALKQGQITPTELCQKCLSLIKKT-KFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNF 79
Cdd:COG0154    4 LAELSAAELAAALRAGEVSAVELVEAALARIEAVnPALNAFVTVDAERALAEARAADARRAAGEALGPLAGVPVAVKDLI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqNPHse 159
Cdd:COG0154   84 DVAGLPTTAGSKALADFVPPYDATVVARLRAAGAVILGKTNMPEFAMGGSTENSAYGPTRNPW------------DPDrt 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 160 nedsdwlitggssggSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:COG0154  152 pgg--------ssggSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASSLDQVGPLARTVAD 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 240 AAIVLGALAGPDPRDSTTVHEPInKPFMLPSLADVSKLCIGIPKEYLVPE-LSSEVQSLWSKAADLFESEGAKVIEVSLP 318
Cdd:COG0154  224 AALLLDVLAGPDPRDPTSAPAPV-PDYLAALDRDLKGLRIGVPREYFGGDgVDPEVAAAVEAAAAALEALGAEVVEVDLP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 319 HTSYSIVCYHVLCTSEVASNMArfdglqyghrcdidvsteAMYaATRREGFNDVVRGRILSGNFFllkenYENYFVKAQK 398
Cdd:COG0154  303 DLDEALAAYYTIAAAEAAANLA------------------DLL-RTRPEGFGPEVRRRILLGAYY-----SAADYLKAQR 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 399 VRRLIANDFVNAFNsGVDVLLTPTTLSEAVPYLEFIKEDN--RTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQ 476
Cdd:COG0154  359 VRALLRRDFAAAFE-DYDVLLTPTTPTPAPPIGELDADIDpaLAMNYLLDRFTAPANLAGLPALSVPAGFTADGLPVGLQ 437

                        490       500
                 ....*....|....*....|
gi 222831590 477 FIGRAFCDQQLLTVAKWFEK 496
Cdd:COG0154  438 LIGPPGDEATLLRLAAALEQ 457
gatA TIGR00132
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase ...
 11-496 2.80e-160

aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; In many species, Gln--tRNA ligase is missing. tRNA(Gln) is misacylated with Glu after which a heterotrimeric amidotransferase converts Glu to Gln. This model represents the amidase chain of that heterotrimer, encoded by the gatA gene. In the Archaea, Asn--tRNA ligase is also missing. This amidase subunit may also function in the conversion of Asp-tRNA(Asn) to Asn-tRNA(Asn), presumably with a different recognition unit to replace gatB. Both Methanococcus jannaschii and Methanobacterium thermoautotrophicum have both authentic gatB and a gatB-related gene, but only one gene like gatA. It has been shown that gatA can be expressed only when gatC is also expressed. In most species expressing the amidotransferase, the gatC ortholog is about 90 residues in length, but in Mycoplasma genitalium and Mycoplasma pneumoniae the gatC equivalent is as the C-terminal domain of a much longer protein. Not surprisingly, the Mycoplasmas also represent the most atypical lineage of gatA orthology. This orthology group is more narrowly defined here than in Proc Natl Acad Aci USA 94, 11819-11826 (1997). In particular, a Rhodococcus homolog found in association with nitrile hydratase genes and described as an enantiomer-selective amidase active on several 2-aryl propionamides, is excluded here. It is likely, however, that the amidase subunit GatA is not exclusively a part of the Glu-tRNA(Gln) amidotransferase heterotrimer and restricted to that function in all species. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272925 [Multi-domain]  Cd Length: 460  Bit Score: 463.73  E-value: 2.80e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   11 AALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRykngqSLGDLDGIPIAVKDNFSTSGIETTCA 89
Cdd:TIGR00132   3 QLLKKKEISIKEVLEASLDRIEANKdKINAFLEVTVEKALKQAKKLDKA-----ILTPLAGIPIAVKDNISTKGIVTTCA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqnphseNEDsdwLITG 169
Cdd:TIGR00132  78 SKILENYIPPYDATVIERLKQAGALIIGKTNMDEFAMGSSTETSAFGPTKNPW-----------------NLD---RVPG 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  170 GSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAG 249
Cdd:TIGR00132 138 GSSGGSAAAVAADLAPFSLGSDTGGSIRQPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFARTVEDIALLLDVISG 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  250 PDPRDSTTVHEPInkPFMLPSLADVSK-LCIGIPKEYLvPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYH 328
Cdd:TIGR00132 218 HDKRDSTSAKVPD--PEFFEELKKDLKgLKVGVVKEFS-EEMDKEVQEKFENALEVLEELGAEIVEVSFPHVKYALPIYY 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  329 VLCTSEVASNMARFDGLQYGHRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFV 408
Cdd:TIGR00132 295 IISPSEASSNLARYDGIRYGYRIEEPNSLKELYAKTRAEGFGEEVKRRIMLGNYALSAGYYDKYYLKAQKVRTLIIDDFL 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  409 NAFnSGVDVLLTPTTlseavPYLEFI---KEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQ 485
Cdd:TIGR00132 375 KLF-EEVDVIVSPTA-----PTLPFKigeKLDDPLEMYLSDILTVPANLAGLPAISVPCGVKEKGLPIGLQIIGKCFDDK 448

                         490
                  ....*....|.
gi 222831590  486 QLLTVAKWFEK 496
Cdd:TIGR00132 449 TLLQVSYAFEQ 459
Amidase pfam01425
Amidase;
37-488 3.24e-135

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 398.98  E-value: 3.24e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   37 LNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLM 116
Cdd:pfam01425  17 LNAFVTVFFDEALAQAAAADKQRAAGDPKGPLHGVPIAVKDNIDVKGVPTTAGSKALENYPAPYDATVVERLRKAGAVIL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  117 GKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqnphseneDSDW-----------LItggssggsaaavSAFTCY 185
Cdd:pfam01425  97 GKTNMDEFAMGSSTENSVFGPTRNPW-------------------DLSRtpggssggsaaAV------------AAGLVP 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  186 AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPInKP 265
Cdd:pfam01425 146 LAIGTDTGGSIRIPASFCGLVGLKPTYGRVSRYGVVGYASSLDQVGPLARSVEDAALLLRVISGYDPKDSTSLPPPV-PD 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  266 FMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGl 345
Cdd:pfam01425 225 YAEPVKKSLKGLRIGVYREDGYFDLDPEVRRAVEEALAQLEALGHEVVEVDPPSLDYALPLYYLIAPAEASSNLARYDG- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  346 qyghRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLS 425
Cdd:pfam01425 304 ----VPSGPDDLSELYPRTRAEGLGDEVKRRIILGNYALSAGYYDKYYLKAQKVRRLIRREFAGLFEE-LDVLLSPTAPT 378

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 222831590  426 EAVPYLEFikEDNRTRSAQDDIFTQA---VNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLL 488
Cdd:pfam01425 379 PAPRLGEP--DDSPLVMYNLDDFTAGvvpVNLAGLPAISLPAGFTADGLPVGVQIIGKPGDEETLL 442
PRK07139 PRK07139
amidase; Provisional
 75-496 1.04e-76

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 248.42  E-value: 1.04e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  75 VKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQ 154
Cdd:PRK07139  44 IKDNFATSEGPTHASSKSLENFKPSYNATVVQKLINAGAKPVAKVHCDELGLGGTGLFSAFGLIKNPLDSSKLVGGSSSG 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 155 NPHSENEDSDWlitggssggsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK07139 124 SAATFNKNISF---------------------AIGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYASSLDTVAYFT 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 235 RCVDDAAIVLGALAGPDPRDSTTVHEPIN-----KPFMLPSLaDVSKlcigipkeylvpELSSEVQSLWSKAADLFESEG 309
Cdd:PRK07139 183 HNVNDAIILSKVLFGKDENDLTSVDVKINnvkktKPKKVAYL-DCFK------------ELEEYVAKKYKKLINILKSEN 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 310 AKVIEVSLPH-------TSYSIVCYhvlctSEVASNMARFDGLQYGHRCDIDvSTEAMYAATRREGFNDVVRGRILSGNF 382
Cdd:PRK07139 250 IEVEKIKIDEkllkaikPVYKIISY-----SEASSNLANLNGIAFGNREKGS-SWEEIMINTRSEGFGKMVQKRLILGSY 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 383 FLLKENYENYFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAvPYLEFIKEDNrtRSAQDDIFTQAvNMAGLPAVSI 462
Cdd:PRK07139 324 FLEEENQEKYFLKAKKVRRVIKNYYESIHNK-FDIVIYPAYADIA-PDIDENENKS--DNYMDYILTIS-NLVGNPSLSI 398

                        410       420       430
                 ....*....|....*....|....*....|....
gi 222831590 463 PVAlSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07139 399 PLG-KYNNLPFNLAIDSKIYDDEKLLSYSLYIEE 431
PRK07488 PRK07488
indoleacetamide hydrolase;
5-496 5.22e-75

indoleacetamide hydrolase;


Pssm-ID: 236030 [Multi-domain]  Cd Length: 472  Bit Score: 244.88  E-value: 5.22e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGdLDGIPIAVKDNFSTSGI 84
Cdd:PRK07488  12 SLTEAAAALRSGRLSCLELVEALLARAAALAPLNAFTTVDAEGALAAARRIDAQRAAGAALL-LAGVPIVIKDNINTAGM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  85 ETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSkqyrekrkqnphsenedsd 164
Cdd:PRK07488  91 PTTAGTPALLGFVPATDAPVVQRLLDAGAVPLGKANMHELAFGITSNNGAFGAVRNPYDPA------------------- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 165 wLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVL 244
Cdd:PRK07488 152 -RIAGGSSGGTAAAVAARLAPAGLGTDTGGSVRIPAALCGVVGLRPTVGRYSGDGVVPISHTRDTVGPIARSVADLALLD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 245 GALAGPDPrdsttvhepinkpfmLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPH----- 319
Cdd:PRK07488 231 AVITGDAA---------------LPAPVALAGLRLGVPAAPFWDGLDPDVAAVAEAALAKLAAAGVTFVELDLPGlheln 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 320 --TSYSIVCYHvlctsevasnmARFDGLQYGHRCDIDVSTEAMYAATR----REGFNDVVRGRILSGnffllkenyENYF 393
Cdd:PRK07488 296 eaVGFPIALYE-----------ALADLRAYLRENGAGVSFEELVARIAspdvRAIFRDLLDPPQISE---------DAYR 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 394 VKAQKVRRLIANDFVNAF-NSGVDVLLTPTTLSEAVPylefIKEDNRT--RSAQDDIFTQAV-NM-----AGLPAVSIPV 464
Cdd:PRK07488 356 AALDVGRPRLQAWYRQAFaRHGLDAILFPTTPLTAPP----IGDDDTVilNGAAVPTFARVIrNTdpasnAGLPGLSLPA 431

                        490       500       510
                 ....*....|....*....|....*....|..
gi 222831590 465 ALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK07488 432 GLTPHGLPVGLELDGPAGSDRRLLAIGRALER 463
PRK07235 PRK07235
amidase; Provisional
 62-498 6.69e-62

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 211.02  E-value: 6.69e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  62 GQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNP 141
Cdd:PRK07235  82 GAAEGKLAGKTVALKDNVAVAGVPMMNGSSTLEGFVPSFDATVVTRLLDAGATIVGKATCEDLCFSGGSHTSDPGPVHNP 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 142 WsyskqyrekrkqNP-HSENEDSdwlitggssGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGL 220
Cdd:PRK07235 162 R------------DPgYSAGGSS---------SGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGA 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 221 IPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLCIGIPKE-YLVPELSSEVQSLWS 299
Cdd:PRK07235 221 FPIERTIDHLGPMTATVRDNALLLEVIAGRDGLDPRQPAQPPVDDYTAALDRGVKGLKIGILREgFGLPNSEPEVDEAVR 300

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 300 KAADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVSTEAMYAATRRE---GFNDVVRGR 376
Cdd:PRK07235 301 AAAKRLEDLGATVEEVSIPLHRLALAIWNPIATEGATAQMMLGNGYGFNWKGLYDTGLLDAFGAGWREradDLSETVKLV 380

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 377 ILSGNFFLlkENYEN-YFVKAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAVPYLEfikednrTRSAQDDIFTQAVNM- 454
Cdd:PRK07235 381 MLLGQYGL--ERYHGrYYAKARNLARRLRAAYDEALRK-YDLLVMPTTPMVATPLPA-------PDASREEYVSRALEMi 450

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|..
gi 222831590 455 --------AGLPAVSIPVALSNqGLPIGLQFIGRAFCDQQLLTVAKWFEKQV 498
Cdd:PRK07235 451 antapfdvTGHPAMSVPCGLVD-GLPVGLMLVGRHFDEATILRAAAAFEASG 501
PRK09201 PRK09201
AtzE family amidohydrolase;
5-505 5.22e-58

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 199.81  E-value: 5.22e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSG 83
Cdd:PRK09201   8 SAAEIAAAVRAGELSARAVAQATLARIARANpQLNAFTAVTAERALAEAARIDAARAAGEPLGPLAGVPFAVKNLFDVAG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  84 iETTCASNMLKGYIPP--YNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPwsyskqyrekrkqnpHSENE 161
Cdd:PRK09201  88 -LTTLAGSKINRDRPPatRDATAVRRLEAAGAVLVGALNMDEYAYGFTTENSHYGATRNP---------------HDLTR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 162 dsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAA 241
Cdd:PRK09201 152 -----IAGGSSGGSAAAVAAGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPFVASLDHIGPFARSVADLA 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 242 IVLGALAGPDPRDSTTVHEPINKpfMLPSL-ADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESegakVIEVSLPHT 320
Cdd:PRK09201 227 LVYDVLQGPDPQDPFQADRPAEP--TAPLLdRGAEGLRIAVLGGYFAQWADPEARAAVDRVAKALGA----TREVELPEA 300

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 321 SYSIVCYHVLCTSEVASNmarfdglqygHRCDIdvsteamyaATRREGFNDVVRGRILSGnfFLLKenyENYFVKAQKVR 400
Cdd:PRK09201 301 ARARAAAFIITASEGGNL----------HLPAL---------RTRPQDFDPASRDRLLAG--AMLP---AAWYVQAQRFR 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 401 RLIANDFVNAFNSgVDVLLTPTTLSEAvPYL--EFIKEDNRTRSAQDD--IFTQAVNMAGLPAVSIPVALSNqGLPIGLQ 476
Cdd:PRK09201 357 RWFRQAVLELFEH-VDVLIAPATPCSA-PLIgqETMRIDGVELPVRANlgILTQPISFIGLPVVAVPLRTPG-GLPIGVQ 433

                        490       500       510
                 ....*....|....*....|....*....|.
gi 222831590 477 FIGRAFCDQQLLTVAKWFEKQ--VQFPVIQL 505
Cdd:PRK09201 434 LIAAPWREDLALRAAAALEQQgvAAAPVPTV 464
PRK06169 PRK06169
putative amidase; Provisional
 8-496 6.03e-55

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 191.77  E-value: 6.03e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIET 86
Cdd:PRK06169  11 ELLAAYRRGELSPVEATQAVLDRIDRrDPAVNAFCLVDAEGALAAARASEERWRRGEPCGLLDGVPVSIKDIFLTRGWPT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  87 TCASNMLKGYIP-PYNATVVQKLLDQGALLMGKTNLDEFAMgSGSTDG-VFGPVKNPWSYSKqyrekrkqNPHSENEDSd 164
Cdd:PRK06169  91 LRGSRAIDADGPwDVDAPAVARLREAGAVLLGKTTTPEFGW-KGVTDSpLYGITRNPWDTRL--------TAGGSSGGA- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 165 wlitggssggsaaavsafTCYAAL-------GSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLvNSMDVPGILTRCV 237
Cdd:PRK06169 161 ------------------AAAVALgmgplsvGTDGGGSVRIPASFCGTFGFKPTFGRVPLYPASPF-GTLAHVGPMTRTV 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 238 DDAAIVLGALAGPDPRDSTTVhEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSL 317
Cdd:PRK06169 222 ADAALLLDVIARPDARDWSAL-PPPTTSFLDALDRDVRGLRIAYSPTLGYVDVDPEVAALVAQAVQRLAALGARVEEVDP 300

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 318 PHTSySIVCYHVLCTSEVASNMARFdGLQYGHRCDidvsteamyaatrrEGFNDVV-RGRILSGNFFLlkenyenyfvKA 396
Cdd:PRK06169 301 GFSD-PVEAFHVLWFAGAARLLRAL-PPGQRALLD--------------PGLRRIAeRGATYSASDYL----------DA 354

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 397 QKVRR-LIANdfVNAFNSGVDVLLTPTtlseaVPYLEF-IKEDNRTRSAQDDI-----FTQAVNMAGLPAVSIPVALSNQ 469
Cdd:PRK06169 355 TAVRAaLGAR--MGAFHERYDLLLTPT-----LPIPAFeAGHDVPPGSGLTDWtqwtpFTYPFNLTQQPAASVPCGFTAA 427

                        490       500
                 ....*....|....*....|....*..
gi 222831590 470 GLPIGLQFIGRAFCDQQLLTVAKWFEK 496
Cdd:PRK06169 428 GLPVGLQIVGPRHSDDLVLRVARAYEQ 454
PRK08186 PRK08186
allophanate hydrolase; Provisional
 1-504 3.22e-53

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 190.05  E-value: 3.22e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   1 MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYIT-VSEEVALKQAEESEKRYkngQSLGDLDGIPIAVKDNF 79
Cdd:PRK08186   4 PTDLTLASLRAAYRAGTLTPRAVVAALYARIAAVDDPEVWIHlRPEADLLAQAAALEARD---PAALPLYGVPFAVKDNI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSGIETTCASNMLkGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqnphse 159
Cdd:PRK08186  81 DVAGLPTTAACPAF-AYTPERDATVVARLRAAGAIVIGKTNLDQFATGLVGTRSPYGAVRNAF----------------- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 160 neDSDwlitggssggsaaavsaftcY-------------------AALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGL 220
Cdd:PRK08186 143 --DPE--------------------YvsggsssgsavavalglvsFALGTDTAGSGRVPAAFNNIVGLKPTLGLLSTRGV 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 221 IPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPsladvSKLCIGIPK----EYLVPELSsevQS 296
Cdd:PRK08186 201 VPACRTLDCVSVFALTVDDADAVLAVMAGFDPADPYSRANPADAPAALP-----AGPRVGVPRaaqlEFFGDAEA---EA 272

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 297 LWSKAADLFESEGAKVIEVslphtsysivcyhvlctsevasnmarfdglqyghrcDIDVSTEAM------------YAA- 363
Cdd:PRK08186 273 AFAAALARLEALGAELVEI------------------------------------DFSPFLEAArllyegpwvaerYAAv 316

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 364 -----TRREGFNDVVRGRILSGNFF----LLKENYenyfvKAQKVRRLIANDFvnafnSGVDVLLTPTTlsEAVPYLEFI 434
Cdd:PRK08186 317 gefleAHPDAVDPVVRGIIAGAAAFsaadAFRALY-----RLAELRRAAEAVL-----AGIDALLVPTA--PTHPTIAEV 384

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 435 KEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQ 504
Cdd:PRK08186 385 AADPIGLNSRLGTYTNFVNLLDLCALAVPAGFRADGLPFGVTLIAPAFADQALADLAARLQAALALPLGG 454
PRK07042 PRK07042
amidase; Provisional
 5-495 3.87e-53

amidase; Provisional


Pssm-ID: 235915 [Multi-domain]  Cd Length: 464  Bit Score: 186.72  E-value: 3.87e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSG 83
Cdd:PRK07042   8 SAVELLAGYRARSLSPVEVTEAVLAHIARWEpHLNALYAFDPEAARAAARASTARWAKGEPLGPLDGVPVTIKENIATRG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  84 IETT--CASNMLKgyIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSkqyrekrkQNPHSENE 161
Cdd:PRK07042  88 VPVPlgTAATDLP--PAAADAPPAARLREAGAVILAKTTMPDYGMLSSGLSSFHGLTRNPWDLD--------QNPGGSSA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 162 DSDwlitggssggsaaavsaftcyAA---------LGSDTGGSTRNPAAHCGLVGFKPSyglvsrHGLIPLvnsmDVP-- 230
Cdd:PRK07042 158 GAG---------------------AAaaagygplhLGTDIGGSVRLPAGWCGIVGLKPS------LGRIPI----DPPyt 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 231 ----GILTRCVDDAAIVLGALAGPDPRDSTTV-HEPINkpfmLPSLA-DVSKLCIGIpkeYLVP----ELSSEVQSLWSK 300
Cdd:PRK07042 207 grcaGPMTRTVDDAALLMSVLSRPDARDGTSLpPQDID----WSDLDiDVRGLRIGL---MLDAgcglAVDPEVRAAVEA 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 301 AADLFESEGAKVIEVSLphtsysivcyhVLctsevasNMARFDGLQ--YGHRCDIDVSteamyaatrreGFNDVVRGRIL 378
Cdd:PRK07042 280 AARRFEAAGAIVEPVPP-----------FL-------TRAMLDGLDrfWRARLWSDLA-----------ALPPERRAKVL 330

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 379 SgnffllkenyenYFVK-AQKVRRLIANDFVNAFN-------------SGVDVLLTPTTLSEAVPyLEFIKEDNRTRSAQ 444
Cdd:PRK07042 331 P------------YIRRwAEGGADLSGVEAVRGFNqtfamraaaarlfAEFDYVLSPVAPVPAFP-AEWASPTNDPARPF 397

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|..
gi 222831590 445 DDI-FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFE 495
Cdd:PRK07042 398 EHIaFTVPWNMSEQPAASINCGFTRDGLPIGLQIVGPRFDDLGVLRLAKAFE 449
PRK06170 PRK06170
amidase; Provisional
 4-495 9.15e-50

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 178.30  E-value: 9.15e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   4 RSLREVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQsLGDLDGIPIAVKDNFSTS 82
Cdd:PRK06170  12 LPATELAAALAAGEVSSVELTDLAIARIERhDGKINAIVVRDFDRARAAARAADAARARGE-RGPLLGIPVTVKESFNVA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  83 GIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKqyrekrkqNPHSENED 162
Cdd:PRK06170  91 GLPTTWGFPDLRDYVPAEDAVAVARLKAAGAVILGKTNVPLGLQDWQSYNEIYGTTNNPWDLAR--------TPGGSSGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 163 SdwlitggssggSAAAVSAFTcYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVN-------SMDVPGILTR 235
Cdd:PRK06170 163 S-----------AAALAAGFG-ALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIPPPApalpgqaDLAVAGPMAR 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 236 CVDDAAIVLGALAGPDPRDSTTVHEpinkpFMLP-----SLADVSKLCIgiPKEYLVPeLSSEVQSLWSKAADLFESEGA 310
Cdd:PRK06170 231 SARDLALLLDVMAGPDPLDGGVAYR-----LALPparhgRLKDFRVLVL--DEHPLLP-TDAAVRAAIERLAAALADAGA 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 311 KVIEVS--LPHTSysiVCYHVLCTSEVASNMARFDGLQYGhrcdiDVSTEAM--------YAATRRegfndvvRGRILSG 380
Cdd:PRK06170 303 RVVRHSplLPDLA---ESARLYMRLLFAASAARFPPDAYA-----DAQARAAglsaddrsLAAERL-------RGAVLSH 367

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 381 NFFLLkenyenyfvkAQKVRRLIANDFVNAFNSgVDVLLTPTTLSEAVPYLEFIKEDNRTRS---AQDDIFTQAV----- 452
Cdd:PRK06170 368 RDWLF----------ADAAREELRAAWRRFFAE-FDVVLCPVTPTPAFPHDHAPDPLERRIDidgVSYPYWDQLVwagla 436

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 222831590 453 NMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFE 495
Cdd:PRK06170 437 TLPGLPATAIPIGLSATGLPVGVQIVGPALEDRTPLRLAELLE 479
PRK08137 PRK08137
amidase; Provisional
 5-499 1.76e-47

amidase; Provisional


Pssm-ID: 236161 [Multi-domain]  Cd Length: 497  Bit Score: 172.26  E-value: 1.76e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKKTK----FLNAYITVSEEvALKQAEESEKRYKNGQSLGDLDGIPIAVKDNF- 79
Cdd:PRK08137   7 RAGALQAAMPAGAAPASQLTRAYLQRIARIDrdgpRLNAVIELNPD-AEADAAALDAERKAGKVRGPLHGIPVLLKDNId 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFA-----MGSGSTDGVFGPVKNPwsyskqYREKRkq 154
Cdd:PRK08137  86 AADPMPTTAGSLALAGNRPTRDAFLVARLRDAGAVILGKANLSEWAnfrstRSSSGWSARGGLTRNP------YALDR-- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 155 NPHSENEDSDWLITGGSSGgsaaavsaftcyAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILT 234
Cdd:PRK08137 158 SPCGSSSGSGAAVAAGLAA------------VAIGTETDGSITCPAAINGLVGLKPTVGLVSRDGIVPISHSQDTAGPMT 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 235 RCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPSL-ADVSK-LCIGIPKEYLvpELSSEVQSLWSKAADLFESEGAKV 312
Cdd:PRK08137 226 RTVADAAAVLTAIAGGDPADPATASAPAPAVDYVAALdADALRgARLGVARNYL--GYHPEVDAQFERALAELKAAGAVV 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 313 IEVSLP-HTSYSIVCYHVLCTsEVASNMARFdgLQyGHRCDIDVSTEAMYAAtrregFNDVVRGRILS--GNFFLLKENY 389
Cdd:PRK08137 304 IDVVDLdDGDWGEAEKVVLLH-EFKAGLNAY--LR-STAPHAPVRTLADLIA-----FNRAQHAREMPyfGQELFEQAQA 374

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 390 EN------YFVKAQKVRRLIANDFVNAF--NSGVDVLLTPTTlSEAVPyLEFIKEDNRTRSaqddiFTQAVNMAGLPAVS 461
Cdd:PRK08137 375 APglddpaYLDALADAKRLAGPEGIDAAlkEHRLDALVAPTT-GPAWL-IDLINGDSFGGS-----SSTPAAVAGYPHLT 447

                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 222831590 462 IPVALSnQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK08137 448 VPMGQV-QGLPVGLSFIGAAWSEARLLELGYAYEQATH 484
PRK07056 PRK07056
amidase; Provisional
 6-499 7.66e-42

amidase; Provisional


Pssm-ID: 235921 [Multi-domain]  Cd Length: 454  Bit Score: 155.86  E-value: 7.66e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   6 LREVSAALKQGQITPTELCQKCLSLI--KKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSG 83
Cdd:PRK07056   8 LAALAADLAAGRTTSRALVEAALARIadPAGEGARVFTHVDADAARAAADAADALRAAGAAPSPLAGIPVSVKDLFDVAG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  84 IETTCASNMLKGYIP-PYNATVVQKLLDQGALLMGKTNLDEFAMgSGStdGV---FGPVKNPWSYSKQyrEKRkqnphse 159
Cdd:PRK07056  88 QVTRAGSRVLADAPPaAADAPAVARLRRAGAVLIGRTNMTEFAF-SGL--GLnphYGTPRNPWRRDVG--DGR------- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 160 nedsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDD 239
Cdd:PRK07056 156 -------IPGGSSSGAAVSVADGMAAAALGTDTGGSIRIPAALCGLTGFKPTARRVPLQGAVPLSTTLDSIGPLARSVAC 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 240 AAIVLGALAGPDPRDsttvhepinkpfmlPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPH 319
Cdd:PRK07056 229 CALVDAVLAGEEPVV--------------PAARPLEGLRLAVPTTVVLDGLDATVAAAFERALKRLSAAGAIIEEIAFPE 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 320 tsysivcyhvlcTSEVASNMARFdGLQyghrcdidvSTEAmYA------ATRREGFNDVVRGRILSGNffllKENYENYF 393
Cdd:PRK07056 295 ------------LAELAEINAKG-GFS---------AAES-YAwhrpllARHRDQYDPRVAARILRGE----PMSAADYI 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 394 VKAQKVRRLIANdfVNAFNSGVDVLLTPTTlseAV--PYLEFIKEDnrtrsaqDDIFTQA----------VNMAGLPAVS 461
Cdd:PRK07056 348 DLLAARAAWIAR--AAARLARFDALVMPTV---PIvpPRIADLEAD-------DAAFFRTnalllrnpslINFLDGCALS 415

                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 222831590 462 IPVALSNQgLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK07056 416 LPCHAPGE-APVGLMLAGAPGRDDRLLAIALAVEAVLR 452
PRK06102 PRK06102
amidase;
3-491 1.41e-41

amidase;


Pssm-ID: 235698 [Multi-domain]  Cd Length: 452  Bit Score: 154.81  E-value: 1.41e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   3 GRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTS 82
Cdd:PRK06102   5 AKSAAQLAVLIQSGALDPVQVAEQALDAIASYADQAVFISLTEERAMREAEASSARWRAGRSLGLLDGIPIAWKDLFDVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  83 GIETTCASNMLKGYIPP-YNATVVQKLLDQGALLMGKTNLDEFAMgSGStdGVfgpvkNPwsyskQYREKRkqNPHSENE 161
Cdd:PRK06102  85 GSVTTAGSVVLANAAPAsRDAAVVALLARAGMVSIGRTNMSEFAF-SGL--GL-----NP-----HYGTPV--NPRSTDV 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 162 DSdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAA 241
Cdd:PRK06102 150 PR---IPGGSSSGSAVAVAAGLVPVAMGTDTGGSVRIPAAFNGLVGYKATRGRYSMDGVFPLAKSLDSLGPLCRSVRDAV 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 242 IVLGALAGPDPRDSTTVhepinkpfmlpSLADVSKLcigIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLP--H 319
Cdd:PRK06102 227 WIDAAMRGLTAPDVVRR-----------PLAGLRLV---VPETVVFDDAEPGVRAAFEAAVERLQAAGALVERQAFPafQ 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 320 TSYSIVCYH-VLCTSEV-ASNMARFDG---LQYGHRcdidvsteamyaatrregfndvVRGRILSGNFFLLkenyENYFV 394
Cdd:PRK06102 293 EILDLIARHgWLVTAEAfALHQERLDGpdaARMDPR----------------------VVKRTRLGRKITA----SDYIA 346

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 395 KAQKVRRLIAndfvnAFNSGVD--VLLTPTTLSEAvPYLEFIKEDnrtrsaqDDIFTqAVNMAGL-----------PAVS 461
Cdd:PRK06102 347 LLEARERLIA-----QVTRELGgaLLATPTVAHVA-PPLAPLEAD-------DDLFF-ATNLKTLrntmpgnfldmCGVS 412

                        490       500       510
                 ....*....|....*....|....*....|
gi 222831590 462 IPVALSNQGLPIGLQFIGRAFCDQQLLTVA 491
Cdd:PRK06102 413 LPCGTGAAGMPVGLLLSAPAGRDERLLRAA 442
PRK06061 PRK06061
amidase; Provisional
 6-497 3.96e-40

amidase; Provisional


Pssm-ID: 235686 [Multi-domain]  Cd Length: 483  Bit Score: 151.77  E-value: 3.96e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   6 LREVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQSLgDLDGIPIAVKDNFSTSGI 84
Cdd:PRK06061  20 LTDQAYQLASGAVTSVELVRRSLRRIEASQpTLNAFRVVRAEAALAEAAEADRRRAAGDRL-PLLGVPIAVKDDVDVAGV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  85 ETT--CAsnmlkGYIPP--YNATVVQKLLDQGALLMGKTNLDE-----FAMGSGstdgvFGPVKNPWSyskqyREkrkqn 155
Cdd:PRK06061  99 PTAfgTA-----GEVPPatADSEVVRRLRAAGAVIVGKTNTCElgqwpFTSGPA-----FGHTRNPWS-----RD----- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 156 pHSENEDSDwlitggssgGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTR 235
Cdd:PRK06061 159 -HTPGGSSG---------GSAAAVAAGLVTAAIGSDGAGSVRIPAAWTHLVGIKPQRGRISTWPLPEAFNGLTVNGPLAR 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 236 CVDDAAIVLGALAGPDPRDsttVHEPinKPFMLPSLA--DVSKLCIG----IPKEYLVPELSSEVQSLWSKAADLFESEG 309
Cdd:PRK06061 229 TVADAALLLDAASGNHPGD---RHRP--PPVTVSDAVgrAPGPLRIAlstrFPFTGFPAKLHPEIRAAVRRVAEQLALLG 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 310 AKVIEVSLPhtsYSIvcyhVLCTSEVASNMArfdGL-----QYGHRCDIDVSTEamyAATRregfndvvRGRILSGNFFL 384
Cdd:PRK06061 304 HTVVPADPD---YGL----RLGLNFLPRSTA---GLrdwaeRLGDPVLLDPRTV---SNAR--------MGRLLSQAILR 362

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 385 LKENYEnyfVKAQkvRRLIAndfvnAFNSgVDVLLTPTTlseAVPYLEFIKEDNRTRSAQDDIFTQAV------NMAGLP 458
Cdd:PRK06061 363 LARAAE---AAAQ--RRVGS-----IFDI-VDVVLAPTT---AQPPPRVGAFDRLGGWATDRAMIAACpytwpwNVLGWP 428

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*.
gi 222831590 459 AVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVA-------KWFEKQ 497
Cdd:PRK06061 429 SINVPAGFTSDGLPIGAQLMGPANSEPLLISLAaqleavsGWAERQ 474
PRK06828 PRK06828
amidase; Provisional
 5-498 9.30e-40

amidase; Provisional


Pssm-ID: 180715 [Multi-domain]  Cd Length: 491  Bit Score: 150.74  E-value: 9.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLI----KKTKFLNAYITVS-EEVALKQAEESEKRYKNgqSLGDLDGIPIAVKDNF 79
Cdd:PRK06828  14 TIHDIQTAMEDGKLTSKELVMYYLHRIakydQDGPKINSILEINpDAIFIAEALDHERKIKG--VRGPLHGIPVLLKDNI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  80 STSG-IETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMgsgstdgvFGPVKNPWSYSKqyREKRKQNPHS 158
Cdd:PRK06828  92 ETNDsMHTSAGTIALEQHISSEDAFLVTKLREAGAVILGKANMTELAN--------FMSFEMWAGYSA--RGGQTINPYG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 159 ENEDSdwLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVD 238
Cdd:PRK06828 162 TGEDD--MFVGGSSTGSAIAVAANFTVVSVGTETDGSILSPAVQNSVVGIKPTVGLISRRGIIPFTYSQDTAGPFARTVT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 239 DAAIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLC---IGI----PKEYLvpELSSEVQSLWSKAADLFESEGAK 311
Cdd:PRK06828 240 DAAILLGSLTGVDEKDVVTHKSEGIAEHDYTKYLDANGLNgakIGVynnaPKEYY--ESGEYDEKLFKETIEVLRSEGAT 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 312 VIE-VSLP--HTSYSIvcyHVLcTSEVASNMARFDGlQYGHRCDIDVSTEAM------------YAATRREGFNDVvrGR 376
Cdd:PRK06828 318 VVEdIDIPsfHREWSW---GVL-LYELKHSLDNYLS-KLPSTIPVHSISELMefneniaeralkYGQTKLERRKDF--PN 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 377 ILSGNFFLLKENYENYFVKAQKVrrlianDFVNAfNSGVDVLLTPTTLSEAVPylefikednrtrsaqddiftqavNMAG 456
Cdd:PRK06828 391 TLRNPEYLNARLEDIYFSQEQGI------DFALE-KYNLDAILFPSYIGSTIC-----------------------AKAG 440

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 222831590 457 LPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQV 498
Cdd:PRK06828 441 YPSIAIPAGYMEGGRPFGITLASTAFSEGTLIKLAYAFEQAT 482
PRK05962 PRK05962
amidase; Validated
 39-499 1.10e-37

amidase; Validated


Pssm-ID: 168315 [Multi-domain]  Cd Length: 424  Bit Score: 143.77  E-value: 1.10e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  39 AYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGiETTCASNMLKGYIPP--YNATVVQKLLDQGALLM 116
Cdd:PRK05962  17 VFSKLYAERARAEADAADARRRAGRSLGPLDGRIVSIKDLFDVAG-EPTLAGSVIRRDAPPagADALIVQRLRNAGAVII 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 117 GKTNLDEFAmgsgstdgvFGPVKnpwsyskqyrekrkQNPH---SENEDSDWLITGGSSGGSAAAVSAFTCYAALGSDTG 193
Cdd:PRK05962  96 GKTHMTEFA---------FTPVG--------------LNPHygePGNAIDPARIPGGSSSGAAVSVAEGTSEIAIGSDTG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 194 GSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRdsttvhepinkPFMLPSLAD 273
Cdd:PRK05962 153 GSVRIPAALNGLVGFKPTARRIPLEGAFPLSPSLDSIGPLARTVADCAAADAVMAGEKPI-----------PLEVLPVAG 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 274 vskLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVslphtsysivcyhvlctsEVASNMARFD-GLQYGHRCD 352
Cdd:PRK05962 222 ---LRIGLPKGYLLADMEPDVAAAFEASLAALEKAGARIADL------------------AIDDLIARLAeATRIGSIAG 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 353 IDVS-TEAMYAATRREGFNDVVRGRILSGnfflLKENYENYFVKAQKVRRLIANdfVNAFNSGVDVLLTPTTLSEAVPyL 431
Cdd:PRK05962 281 IEAShIHADWLADLDANVDIRVKRPLSRR----IKVPLEAYHRLMRTRAALARA--MDERLAGFDMFALPATPIVAPT-I 353

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 222831590 432 EFIKEDNRTRSAQDDIF---TQAVNMAGLPAVSIPvaLSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK05962 354 ASVSEDEEEYDRVENLLlrnTQVANQFDLCSITLP--MPGMALPAGLMLTARNGSDRRLLAAAASVEKLLE 422
PRK07486 PRK07486
amidase; Provisional
 5-501 1.35e-37

amidase; Provisional


Pssm-ID: 236028 [Multi-domain]  Cd Length: 484  Bit Score: 144.39  E-value: 1.35e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYIT-VSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTS 82
Cdd:PRK07486  13 SAHALSRAIRRRQVSCVEVMRAYLAHIERvNPAVNAIVAlRDRDALLAEAAEKDAALARGEYRGWLHGMPQAPKDLAPTK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  83 GIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKqyrekrkqnphSENED 162
Cdd:PRK07486  93 GIRTTLGSPIFADQVPQEDAIVVERMRAAGAIFIGKTNTPEFGLGSHTYNPVYGATRNPYDPSR-----------SAGGS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 163 SDwlitggssggsaaavsafTCYAAL---------GSDTGGSTRNPAAHCGLVGFKPSYGLVSrHGLIP--LVNSMDVPG 231
Cdd:PRK07486 162 SG------------------GAAAALalrmlpvadGSDMMGSLRNPAAFNNVYGFRPSQGRVP-HGPGGdvFVQQLGTEG 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 232 ILTRCVDDAAIVLGALAGPDPRDSTTV-HEPinKPFMLPSLADVSKLCIG--------IPKEylvpelsSEVQSLWSKAA 302
Cdd:PRK07486 223 PMGRTVEDVALLLAVQAGYDPRDPLSLaEDP--ARFAQPLEADLRGKRIAwlgdwggyLPME-------AGVLELCEAAL 293

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 303 DLFESEGAKVIEVSLPHTSYSI-VCYHVLCTSEVASNMArfdglqyghrcdidvsteAMYA--ATRR----EGFNDVVRG 375
Cdd:PRK07486 294 ATLRELGCDVEAALPAFPPERLwRAWLTLRHFLVGGSLL------------------ALYRdpARRAllkpEAIWEIEGG 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 376 RILSGnffllKENYENYFVKA---QKVRRLIANdfvnafnsgVDVLLTPTTlsEAVPYlefikeDNRTR-------SAQD 445
Cdd:PRK07486 356 LALTA-----AQVYEASVIRSawyQALLRLFER---------YDFLALPTA--QVFPF------DAEWRwpraiagRAMD 413

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 222831590 446 DI--FTQAV---NMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFP 501
Cdd:PRK07486 414 TYhrWMEVVvpaTLAGLPAISVPVGFNAAGLPMGMQIIGPPRADLAVLQLAHAYEQATDWV 474
PRK07487 PRK07487
amidase; Provisional
 8-482 2.02e-34

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 135.10  E-value: 2.02e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIET 86
Cdd:PRK07487  12 ELAAAVRSRDVSAREAAEAALARLDAvNPAINAVVDHRPEEALAQADAVDAARARGDDPGPLAGVPVTVKVNVDQAGFAT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  87 TCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWsyskqyrekrkqNPHsenedsdwl 166
Cdd:PRK07487  92 TNGVRLQKDLIAPADSPVVDNLRKAGAVIIGRTNTPAFSYRWFTDNPLHGRTLNPW------------DPS--------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 167 itggssggsaaavsaFTC----------------YAALGSDTGGSTRNPAAHCGLVGFKPSYGLV-------SRHGLipL 223
Cdd:PRK07487 151 ---------------LTPggssggaaaavaagigAIAHGTDIGGSIRYPAYACGVHGLRPTLGRVpaynassPERPI--G 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 224 VNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPSLAdvskLCIGIPKEYLVPelssEVQSLWSKAAD 303
Cdd:PRK07487 214 AQLMSVQGPLARTVADLRLALAAMAAPDPRDPWWVPAPLEGPPRPKRVA----LCVRPDGLDVDP----EVEAALRDAAR 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 304 LFESEGAKVIEVS-LPHTSYSIVCYHVLCTSEVASNMARfDGLQYGhrcdidvsTEAMYAATRreGFNDVVRGRILSGnf 382
Cdd:PRK07487 286 RLEDAGWTVEEVDdTPPLREAAELQERLWLGDGYEALLA-AAEAEG--------DPGALAALR--GQRAKARPLDLAG-- 352

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 383 fllkenyenyFVKAQKVRRLIANDFvNAFNSGVDVLLTPTTLSEAVPYLEFIKEDNRTRSAQDDIFTQ-AVNMAGLPAVS 461
Cdd:PRK07487 353 ----------YMNALARRATLTRQW-QLFFEDYPLLLMPVSAELPFPDDLDRQGAEGFRRVWEAQLPQiALPFMGLPGLS 421

                        490       500
                 ....*....|....*....|.
gi 222831590 462 IPVALSNqGLPIGLQFIGRAF 482
Cdd:PRK07487 422 VPTGLVG-GVPVGVQLVAGRF 441
PRK12470 PRK12470
amidase; Provisional
 8-501 1.51e-33

amidase; Provisional


Pssm-ID: 171524 [Multi-domain]  Cd Length: 462  Bit Score: 132.70  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   8 EVSAALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALKQAEESEKRYKNGQSLgDLDGIPIAVKDNFSTSGIET 86
Cdd:PRK12470  13 AQARMLADGELTAPMLLEVYLQRIERlDSHLRAYRVVLFDRARAEAEAAQQRLDAGERL-PLLGVPIAIKDDVDVAGEVT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  87 TCASnmlKGYIPPY--NATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKqyrekrkqNPHSENEDSD 164
Cdd:PRK12470  92 TYGS---AGHGPAAtsDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWDPNR--------TPGGSSGGSA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 165 WLITGGSSGgsaaavsaftcyAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVL 244
Cdd:PRK12470 161 AAVAAGLAP------------VALGSDGGGSIRIPSTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLL 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 245 galagpdprDSTTVHEPINKPFMLPSLADVSKLCIGIPKEYLVP---ELSSEVQSLWSKAADLFESEGAKVIEVS--LPH 319
Cdd:PRK12470 229 ---------DATTTVPGPEGEFVAAAAREPGRLRIALSTRVPTPlpvRCGKQELAAVHQAGALLRDLGHDVVVRDpdYPA 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 320 TSYSIVCYHVLctsevasNMARFDGLQYGHRCDIDVSTEAMYaatrregfndvvrgRIlsGNFFLLKEnyenyfVKAQKV 399
Cdd:PRK12470 300 ATYANYLPRFF-------RGISDDADAQAHPDRLEARTRAIA--------------RL--GSFFSDRR------MAALRA 350

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 400 RRLIANDFVNAFNSGVDVLLTPTTLSEAVPylefIKEDNRT-------RSAQDDIFTQAVNMAGLPAVSIPVALSNQGLP 472
Cdd:PRK12470 351 AEVVLSARIQSIFDDVDVVVTPGTATGPSR----IGAYQRRgavstllLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLP 426

                        490       500
                 ....*....|....*....|....*....
gi 222831590 473 IGLQFIGRAFCDQQLLTVAKWFEKQVQFP 501
Cdd:PRK12470 427 MSVQLVGRPYDEATLLALAAQIESARPWA 455
PRK07869 PRK07869
amidase; Provisional
 8-504 1.52e-31

amidase; Provisional


Pssm-ID: 181154 [Multi-domain]  Cd Length: 468  Bit Score: 127.02  E-value: 1.52e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   8 EVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEEsekrykNGQSLGDLDGIPIAVKDNFSTSGIET 86
Cdd:PRK07869  19 GLAEAIRAGRVSAAEVVEAAIARAEAVNpALNALAYAAFDRARDRAAR------PGSQGGFFSGVPTFIKDNVDVAGLPT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  87 TCASNMlkgyIPPYNAT----VVQKLLDQGALLMGKTNLDEFAMgSGSTDGV-FGPVKNPWsyskqyrekrkqnphsene 161
Cdd:PRK07869  93 MHGSDA----WTPRPAKadsdFARQFLATGLISLGKTQLPEFGF-SASTEHPrLGPVRNPW------------------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 162 DSDwlitggssggsaaavsaFTC------YAAL----------GSDTGGSTRNPAAHCGLVGFKPSYGlvsRHGLIPLVN 225
Cdd:PRK07869 149 NTD-----------------YSAgassggSAALvaagvvpiahANDGGGSIRIPAACCGLVGLKPSRG---RLPLDPELR 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 226 SMDV----PGILTRCVDDAAIVLGALagpdprdsttvhEPINKPFMLPSLADVSK-----LCIGIPKEYL-VPELSSEVQ 295
Cdd:PRK07869 209 RLPVnivaNGVLTRTVRDTAAFYREA------------ERYYRNPKLPPIGDVTGpgkqrLRIAVVTDSVtGREADPEVR 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 296 SLWSKAADLFESEGAKVIEVSLPHTSySIVCYHVLCTSEVASNMARFDGLQYG---HRCDIDVSTEAMYAATRRegfndv 372
Cdd:PRK07869 277 EAVLATARLLEELGHRVEPVDLPVPA-SFVDDFLLYWGFLAFALVRGGRRTFGpsfDRTRLDNLTLGLARHARR------ 349

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 373 vrgRILSGNFFLLkenyenyfvkaqKVRRLIAnDFVNAFNSgVDVLLTPtTLSEAVPYLEFIKEDNRTRSAQDDI----- 447
Cdd:PRK07869 350 ---NLHRLPLAIA------------RLRRLRR-VYARFFGT-YDVVLTP-TLAHTTPEIGYLDPTQDFDTVLDRLisyva 411

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 222831590 448 FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQ 504
Cdd:PRK07869 412 FTPLQNATGEPAISLPLGQSSDGLPVGMMFSADVGDEATLLELAYELEEAQPWPRIQ 468
PRK06529 PRK06529
amidase; Provisional
 12-500 1.92e-30

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 124.16  E-value: 1.92e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  12 ALKQGQITPTELCQKCLSLIKK-TKFLNAYITVSEEVALkqaEESEKRYKNGQSLGdldGIPIAVKD-NFSTSGIETTCA 89
Cdd:PRK06529  12 AVQQGQVTPLELVTQAIYKAKKlNPTLNAIVSERYEEAL---EEAKQRDFSGKPFA---GVPIFLKDlGQELKGQLSTSG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  90 SNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKqyrekrkqNPHSENEDSDWLITG 169
Cdd:PRK06529  86 SRLFKNYQATKTDLYVKRLEDLGFIILGRSNTPEFGFKNISDSSLHGPVNLPFDNSR--------NAGGSSGGAAALVSS 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 170 GSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSyglvsrHGLIPLVNS-------MDVPGILTRCVDDAAI 242
Cdd:PRK06529 158 GIVAL------------AAASDGGGSIRIPASFNGLIGLKPS------RGRIPVGPGsyrgwqgASVHFALTKSVRDTRR 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 243 VLGALA-----GPDPRDSTT---VHEPINKPFmlpSLADVSKLCIGIPkeylvpeLSSEVQSLWSKAADLFESEGAKVIE 314
Cdd:PRK06529 220 LLYYLQmyqmeSPFPLATLSkesLFQSLQRPL---KIAFYQRSPDGSP-------VSLDAAKALKQAVTFLREQGHEVVE 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 315 VS-LP-HTSYSIVCYHVLCTSEVAsnmARFDGLQ--YGH---RCDIDVSTEAMYAATRRegfndvvrgrILSGNFFLLKE 387
Cdd:PRK06529 290 LEeFPlDMTEVMRSYYIMNSVETA---AMFDDIEdaLGRpmtKDDMETMTWAIYQSGQD----------IPAKRYSQVLQ 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 388 NYENYfvKAQKVRrliandfvnaFNSGVDVLLTPTTLSEAVPYLEFI----------KEDNRTRSAQDDI---------- 447
Cdd:PRK06529 357 KWDTY--SATMAS----------FHETYDLLLTFTTNTPAPKHGQLDpdsklmanlaQAEIFSSEEQQNLvetmfeksla 424

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 222831590 448 ---FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQF 500
Cdd:PRK06529 425 itpYTALANLTGQPAISLPTYETKEGLPMGVQLIAAKGREDLLLGIAEQFEAAGLL 480
PRK06707 PRK06707
amidase; Provisional
 5-499 5.82e-30

amidase; Provisional


Pssm-ID: 235855 [Multi-domain]  Cd Length: 536  Bit Score: 123.48  E-value: 5.82e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   5 SLREVSAALKQGQITPTELCQKCLSLIKKTKF----LNAYITVSEEVALKQAEESEKRYKNGQSlgDLDGIPIAVKDNFS 80
Cdd:PRK06707  72 TVDELQKMIDDGKLSYEELTSIYLFRIQEHDQngitLNSVTEINPNAMEEARKLDQERSRNKKS--NLYGIPVVVKDNVQ 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  81 TSG-IETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFA------MGSGSTdGVFGPVKNPWSyskqyreKRK 153
Cdd:PRK06707 150 TAKvMPTSAGTYVLKDWIADQDATIVKQLKEEGAFVLGKANMSEWAnylsftMPSGYS-GKKGQNLNPYG-------PIK 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 154 QNPHSENEDSDWLITGGSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGIL 233
Cdd:PRK06707 222 FDTSGSSSGSATVVAADFAPL------------AVGTETTGSIVAPAAQQSVVGLRPSLGMVSRTGIIPLAETLDTAGPM 289

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 234 TRCVDDAAIVLGALAGPDPRDSTTvhEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSE---VQSLWSKAADLFESEGA 310
Cdd:PRK06707 290 ARTVKDAATLFNAMIGYDEKDVMT--EKVKDKERIDYTKDLSIDGLKGKKIGLLFSVDQQdenRKAVAEKIRKDLQDAGA 367

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 311 KVievslphtsysivcyhvlcTSEVASNMARFDGLQ-------------YGHRCDIDV-STEAMYAATRREGFNDVVRGR 376
Cdd:PRK06707 368 IL-------------------TDYIQLNNGGVDNLQtleyefkhnvndyFSQQKNVPVkSLEEIIAFNKKDSKRRIKYGQ 428

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 377 IL---SGNFFLLKENYENYFVKAQK-VRRLIANDFVnafNSGVDVLLtpttlseavpyleFIKEDNRTRSAqddiftqav 452
Cdd:PRK06707 429 TLieaSEKSAITKDEFEKVVQTSQEnAKKELDRYLV---EKGLDALV-------------MINNEEVLLSA--------- 483

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 222831590 453 nMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQ 499
Cdd:PRK06707 484 -VAGYPELAVPAGYDNNGEPVGAVFVGKQFGEKELFNIGYAYEQQSK 529
PRK08310 PRK08310
amidase; Provisional
 61-492 3.53e-29

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 118.93  E-value: 3.53e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  61 NGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNAT--VVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPV 138
Cdd:PRK08310  19 PHAASGPLAGLRFAVKDVFDVAGYVTGCGNPDWLAESPVATRTapAVEKLLAAGARFVGKTQTDELAFSLNGQNAHYGTP 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 139 KNPWSYSKqyrekrkqnphsenedsdwlITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRH 218
Cdd:PRK08310  99 VNPAAPDR--------------------VPGGSSSGSAAAVAGGLADFALGTDTGGSVRAPASFCGLYGLRPTHGRISLE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 219 GLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDsttvhEPINKPFMLPSLAdvsklcigipKEYLVPELSSEVQSLW 298
Cdd:PRK08310 159 GVMPLAPSFDTVGWFARDIALLERVGEVLLGDDAQE-----FPLTQRLLIPVDL----------FALLDPAVRAALEAAL 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 299 SKAADLF-ESEGAKVIEVSLPHTSYsivCYHVLCTSEVAsnmarfdgLQYGHRCDidvsteamyaATRREgFNDVVRGRi 377
Cdd:PRK08310 224 ARLRPHLgPAKPASVPPLSLDEWYE---AFRVLQAAEAW--------ETHGAWIS----------SGNPQ-LGPGVADR- 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 378 lsgnfFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLTPTTLSEAvPYLefikedNRTRSAQDDIFTQAVNM--- 454
Cdd:PRK08310 281 -----FAAGAEVTADQVEAARARRAAFARELAALLGPDAVLLLPTVPGAA-PLR------GAPFEALEAYRERALRLlci 348

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|.
gi 222831590 455 ---AGLPAVSIPVAlSNQGLPIGLQFIGRAFCDQQLLTVAK 492
Cdd:PRK08310 349 aglAGLPQISLPLA-SVDGAPFGLSLIGPRGSDRSLLALAQ 388
PRK11910 PRK11910
amidase; Provisional
 1-264 1.66e-28

amidase; Provisional


Pssm-ID: 183377 [Multi-domain]  Cd Length: 615  Bit Score: 119.75  E-value: 1.66e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   1 MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTK----FLNAYITVSEEVaLKQAEESEKryKNGQSLGDLDGIPIAVK 76
Cdd:PRK11910 162 IIGADVTKLQQLIATKQLSYKELAGIYLNRIKKYDqnglNLNAITEINPTI-IAEAEQLDK--ENTTNKSALYGMPVLLK 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  77 DNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAmgSGSTDGVfgpvknPWSYSKqyREKRKQNP 156
Cdd:PRK11910 239 DNIGTKELPTSAGTVALKDWVIGKDATIVENLKANGALILGKTNMSEWA--AGMDEDL------PNGYSG--KKGQSKNP 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 157 HSENEDSdwliTGGSSGGSAAAVSAFTCYAaLGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRC 236
Cdd:PRK11910 309 YSSNLDP----SGSSSGSATAATSDFAAIA-IGTETNGSIITPASAQSAVGYKPSQGLVNNKGIIPLSSRFDTPGPLTRT 383

                        250       260
                 ....*....|....*....|....*...
gi 222831590 237 VDDAAIVLGALAgpdprdSTTVHEPINK 264
Cdd:PRK11910 384 VNDAYLTTNALT------NTTSNPPLST 405
PRK06565 PRK06565
amidase; Validated
 3-495 1.50e-27

amidase; Validated


Pssm-ID: 180626  Cd Length: 566  Bit Score: 116.41  E-value: 1.50e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590   3 GRSLREVSAALKQGQITPTELCQKCLSLIKK-------TKfLNAyITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAV 75
Cdd:PRK06565   6 EVSIAELRAALESGRTTAVELVKAYLARIDAydgpatgTA-LNA-VVVRNPDALKEAEASDARRARGETLGPLDGIPYTA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  76 KDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGsGSTDGVFGpvknpwsyskqyrekRKQN 155
Cdd:PRK06565  84 KDSYLVKGLTAASGSPAFKDLVAQRDAFTIERLRAAGAICLGKTNMPPMANG-GMQRGVYG---------------RAES 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 156 PHSENEDSDWLITGGSSGGSAAAVSAFTCYAaLGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTR 235
Cdd:PRK06565 148 PYNAAYLTAPFASGSSNGAGTATAASFSAFG-LAEETWSSGRGPASNNGLCAYTPSRGVISVRGNWPLTPTMDVVVPYAR 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 236 CVDDAAIVLGALAGPDP-------RDSTTVHEPIN---KPFMLPSLADVSKLC----IGIPKEYLVP------------- 288
Cdd:PRK06565 227 TMADLLEVLDVIVADDPdtrgdlwRLQPWVPIPKAsevRPASYLALAAGADALkgkrFGVPRMYINAdpdagtsenpgig 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 289 -------ELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYsivcyhvlCTSEVASNMARFD-GL---QYGHRCDIDVST 357
Cdd:PRK06565 307 gptgqriHTRPSVIDLWEAARRALEAAGAEVIEVDFPLVSN--------CEGDRPGAPTVFNrGLvspEFLHDELWELSG 378

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 358 EAMYAATRREG------FNDVVRGRILSGNFFLLKENYENY------FVKA---------------------QKVRRLIA 404
Cdd:PRK06565 379 WAFDDFLRANGdpklnrLADVDGPQIFPHDPGTLPNREGDLaagmdeYVNMakrglkswdqiptlpdglrglEKTRKLDL 458

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 405 NDFVNAFnsGVDVLLTPtTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMA----GLPAVSIPV-ALSNQGLPIGLQFIG 479
Cdd:PRK06565 459 EDWMDGL--GLDAVLFP-TVADVGPADADVNPASADIAWSNGVWVANGNLAirhlGVPTVTVPMgVMADIGMPVGLTFAG 535

                        570
                 ....*....|....*.
gi 222831590 480 RAFCDQQLLTVAKWFE 495
Cdd:PRK06565 536 RAYDDNALLRFAAAFE 551
PLN02722 PLN02722
indole-3-acetamide amidohydrolase
 68-298 2.02e-13

indole-3-acetamide amidohydrolase


Pssm-ID: 166363  Cd Length: 422  Bit Score: 72.23  E-value: 2.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590  68 LDGIPIAVKDNFSTSGIETtcasnmlkGYIPP----------YNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGP 137
Cdd:PLN02722  27 LHGLTFAVKDIFDVEGYVT--------GFGNPdwarthsaatSTAPAVLAVLRGGATCVGKTIMDEMAYSINGENAHYGT 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 138 VKNPWSYSKQyrekrkqnPHSENEDSDWLITGGSSGGsaaavsaftcyaALGSDTGGSTRNPAAHCGLVGFKPSYGLVSR 217
Cdd:PLN02722  99 PTNPIAPDRV--------PGGSSSGSAVAVGAKLVDF------------SLGTDTGGSVRVPASYCGIFGFRPSHGAVST 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 222831590 218 HGLIPLVNSMDVPGILTRcvdDAAIV--LGALAGPDPrdsttVHEPInKPFMLPSLADVSKLCiGIPKEYLVPELSSEVQ 295
Cdd:PLN02722 159 VGVIPMAQSFDTVGWFAR---DPVILkrVGHVLLQQP-----DVNPI-KPSQIIIAEDCFQLS-SIPHDRLVQVLVKSVE 228


                 ...
gi 222831590 296 SLW 298
Cdd:PLN02722 229 KLF 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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