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Conserved domains on  [gi|33356130|ref|NP_060997|]
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N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 2 [Homo sapiens]

Protein Classification

TPR and NARP1 domain-containing protein( domain architecture ID 11420148)

TPR and NARP1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NatA_aux_su super family cl26342
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-303 2.16e-46

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


The actual alignment was detected with superfamily member pfam12569:

Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 163.60  E-value: 2.16e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   187 YEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEK 266
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 33356130   267 ALQIST--LEERLQIYEEISKQHPKAITPRRLPLTLVPG 303
Cdd:pfam12569  81 ALGISKedHEALLALYDELAEKYPRSDAPRRLPLDFLEG 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-243 1.51e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 1.51e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  21 YEQKQYKNGLKFCKMILS-NPKFAEhgeTLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEA 99
Cdd:COG0457  19 RRLGRYEEAIEDYEKALElDPDDAE---ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEA 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQ 179
Cdd:COG0457  96 LEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33356130 180 VPPNKIDYEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEA 243
Cdd:COG0457 176 AALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-303 2.16e-46

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 163.60  E-value: 2.16e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   187 YEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEK 266
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 33356130   267 ALQIST--LEERLQIYEEISKQHPKAITPRRLPLTLVPG 303
Cdd:pfam12569  81 ALGISKedHEALLALYDELAEKYPRSDAPRRLPLDFLEG 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-243 1.51e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 1.51e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  21 YEQKQYKNGLKFCKMILS-NPKFAEhgeTLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEA 99
Cdd:COG0457  19 RRLGRYEEAIEDYEKALElDPDDAE---ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEA 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQ 179
Cdd:COG0457  96 LEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33356130 180 VPPNKIDYEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEA 243
Cdd:COG0457 176 AALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 83-291 1.45e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 1.45e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  83 WHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLK 162
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 163 DYDMALKLLEEFRQTqqvPPNKIDYEYSELILYQnqvmREADlLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKE 242
Cdd:COG2956  91 LLDRAEELLEKLLEL---DPDDAEALRLLAEIYE----QEGD-WEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDE 162

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 33356130 243 ASEVFKNLIDRNAENWCYYEGLEK-ALQISTLEERLQIYEEISKQHPKAI 291
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAElYLEQGDYEEAIAALERALEQDPDYL 212
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 39-257 2.74e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 2.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130    39 NPKFAEHGETLAMKGLTLNclgKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILR 118
Cdd:TIGR02917 155 DPRSLYAKLGLAQLALAEN---RFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   119 DLSLLQIQMRDLEGYRETRYQLLQLRPTQ-RASWIGYAIAYHlLKDYDMALKLLEEFRqtqqvppnKIDYEYSELILYQN 197
Cdd:TIGR02917 232 ALATILIEAGEFEEAEKHADALLKKAPNSpLAHYLKALVDFQ-KKNYEDARETLQDAL--------KSAPEYLPALLLAG 302

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   198 QVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAEN 257
Cdd:TIGR02917 303 ASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDD 362
TPR_1 pfam00515
Tetratricopeptide repeat;
87-113 1.47e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 1.47e-03
                          10        20
                  ....*....|....*....|....*..
gi 33356130    87 GLLQRSDKKYDEAIKCYRNALKLDKDN 113
Cdd:pfam00515   8 GNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 87-113 7.76e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.57  E-value: 7.76e-03
                           10        20
                   ....*....|....*....|....*..
gi 33356130     87 GLLQRSDKKYDEAIKCYRNALKLDKDN 113
Cdd:smart00028   8 GNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 187-303 2.16e-46

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 163.60  E-value: 2.16e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   187 YEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEK 266
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 33356130   267 ALQIST--LEERLQIYEEISKQHPKAITPRRLPLTLVPG 303
Cdd:pfam12569  81 ALGISKedHEALLALYDELAEKYPRSDAPRRLPLDFLEG 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-243 1.51e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 1.51e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  21 YEQKQYKNGLKFCKMILS-NPKFAEhgeTLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEA 99
Cdd:COG0457  19 RRLGRYEEAIEDYEKALElDPDDAE---ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEA 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQ 179
Cdd:COG0457  96 LEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33356130 180 VPPNKIDYEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEA 243
Cdd:COG0457 176 AALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
44-283 8.71e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.65  E-value: 8.71e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  44 EHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLL 123
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 124 QIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQtqqvppnkIDYEYSELILYQNQVMREA 203
Cdd:COG0457  86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALE--------LDPDDADALYNLGIALEKL 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 204 DLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQISTLEERLQIYEEI 283
Cdd:COG0457 158 GRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 12-218 5.76e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.25  E-value: 5.76e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  12 NLFKRILKCYEQKQYKNGLKFCKMILS-NPKFAEHGETLamkGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQ 90
Cdd:COG3914  80 LLELAALLLQALGRYEEALALYRRALAlNPDNAEALFNL---GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  91 RSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKL 170
Cdd:COG3914 157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 33356130 171 LEEFRQTQQVPPNKIDYeyseLILYQNQVmREADLLQESLEHIEMYEK 218
Cdd:COG3914 237 EELLAALARGPSELSPF----ALLYLPDD-DPAELLALARAWAQLVAA 279
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 44-287 1.89e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.29  E-value: 1.89e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  44 EHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLL 123
Cdd:COG2956  40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEI 119

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 124 QIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRqtqqvppnKIDYEYSELILYQNQVMREA 203
Cdd:COG2956 120 YEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL--------KLDPDCARALLLLAELYLEQ 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 204 DLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQISTLEERLQIYEEI 283
Cdd:COG2956 192 GDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQ 271


                ....
gi 33356130 284 SKQH 287
Cdd:COG2956 272 LRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 43-220 5.81e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 5.81e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  43 AEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSL 122
Cdd:COG3914  75 LLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 123 LQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMAlklLEEFRQTQQVPPNKIDYEYSEL-ILYQNQVMR 201
Cdd:COG3914 155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA---IAAYRRALELDPDNADAHSNLLfALRQACDWE 231

                       170
                ....*....|....*....
gi 33356130 202 EADLLQESLEHIEMYEKQI 220
Cdd:COG3914 232 VYDRFEELLAALARGPSEL 250
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 64-193 4.83e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.55  E-value: 4.83e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  64 EAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQL 143
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 33356130 144 RPTQRASWIGYAIAYHLLKDYDMALKLLEEFRqtQQVPPNKIDYEYSELI 193
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL--ALLPADAPARLLEASI 128
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
73-279 1.06e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 1.06e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  73 LRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWI 152
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 153 GYAIAYHLLKDYDMALKLLEEFRQtqqvppnkIDYEYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGE 232
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALE--------LDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI 152

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 33356130 233 ILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQISTLEERLQI 279
Cdd:COG0457 153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 83-291 1.45e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 1.45e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  83 WHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLK 162
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 163 DYDMALKLLEEFRQTqqvPPNKIDYEYSELILYQnqvmREADlLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKE 242
Cdd:COG2956  91 LLDRAEELLEKLLEL---DPDDAEALRLLAEIYE----QEGD-WEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDE 162

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 33356130 243 ASEVFKNLIDRNAENWCYYEGLEK-ALQISTLEERLQIYEEISKQHPKAI 291
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAElYLEQGDYEEAIAALERALEQDPDYL 212
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-211 2.43e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 2.43e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  21 YEQKQYKNGLKFCKMILS-NPKFAEhgeTLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEA 99
Cdd:COG0457  53 LRLGRYEEALADYEQALElDPDDAE---ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEA 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 100 IKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEEFRQTQQ 179
Cdd:COG0457 130 IEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRK 209

                       170       180       190
                ....*....|....*....|....*....|..
gi 33356130 180 VPPNKIDYEYSELILYQNQVMREADLLQESLE 211
Cdd:COG0457 210 KLAILTLAALAELLLLALALLLALRLAALALY 241
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-173 4.14e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 4.14e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  43 AEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSL 122
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 33356130 123 LQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEE 173
Cdd:COG4783  81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEK 131
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-147 6.55e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 6.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  21 YEQKQYKNGLKFCKMILSnpKFAEHGETLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAI 100
Cdd:COG4783  15 LLAGDYDEAEALLEKALE--LDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEAL 92

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 33356130 101 KCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147
Cdd:COG4783  93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 86-257 3.49e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 3.49e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  86 YGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYD 165
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 166 MALKLLEEfrqtqqvppnkidyeyselilyqnqvmreadLLQESLEHIEMYEKqicdkllveeiKGEILLKLGRLKEASE 245
Cdd:COG4783  90 EALALLEK-------------------------------ALKLDPEHPEAYLR-----------LARAYRALGRPDEAIA 127

                       170
                ....*....|..
gi 33356130 246 VFKNLIDRNAEN 257
Cdd:COG4783 128 ALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 86-173 6.94e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.11  E-value: 6.94e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  86 YGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYD 165
Cdd:COG5010  60 SDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDD 139


                ....*...
gi 33356130 166 MALKLLEE 173
Cdd:COG5010 140 EAKAALQR 147
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 6-173 7.88e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.42  E-value: 7.88e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   6 LPPKESNLFKRILKCYEQ-KQYKNGLKFCKMILSNPKFAEHgeTLAMKGLTLNCLGKKEEAYEFVRKGLRNDVKSHVCWH 84
Cdd:COG2956 105 LDPDDAEALRLLAEIYEQeGDWEKAIEVLERLLKLGPENAH--AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  85 VYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPtQRASWIGYAIAYHLLKDY 164
Cdd:COG2956 183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP-SDDLLLALADLLERKEGL 261


                ....*....
gi 33356130 165 DMALKLLEE 173
Cdd:COG2956 262 EAALALLER 270
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 39-257 2.74e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 2.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130    39 NPKFAEHGETLAMKGLTLNclgKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILR 118
Cdd:TIGR02917 155 DPRSLYAKLGLAQLALAEN---RFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   119 DLSLLQIQMRDLEGYRETRYQLLQLRPTQ-RASWIGYAIAYHlLKDYDMALKLLEEFRqtqqvppnKIDYEYSELILYQN 197
Cdd:TIGR02917 232 ALATILIEAGEFEEAEKHADALLKKAPNSpLAHYLKALVDFQ-KKNYEDARETLQDAL--------KSAPEYLPALLLAG 302

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   198 QVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNLIDRNAEN 257
Cdd:TIGR02917 303 ASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDD 362
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
87-189 3.72e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 3.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  87 GLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEG----YRETryqlLQLRPTQRASWIGYAIAYHLLK 162
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAaledFDRA----LELDPDYAYAYLNRGIALYYLG 155

                        90       100
                ....*....|....*....|....*..
gi 33356130 163 DYDMALKLLEEFRQTQQVPPNKIDYEY 189
Cdd:COG4785 156 RYELAIADLEKALELDPNDPERALWLY 182
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 54-145 4.71e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.80  E-value: 4.71e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  54 LTLNCLGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGY 133
Cdd:COG5010  62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                        90
                ....*....|..
gi 33356130 134 RETRYQLLQLRP 145
Cdd:COG5010 142 KAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
89-178 7.95e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 7.95e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  89 LQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRyQLLQLRPTQRASWIGYAIAYHLLKDYDMAL 168
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|
gi 33356130 169 KLLEEFRQTQ 178
Cdd:COG3063  80 AYLERALELD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
59-149 1.81e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.55  E-value: 1.81e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130  59 LGKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKcYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRY 138
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83

                        90
                ....*....|.
gi 33356130 139 QLLQLRPTQRA 149
Cdd:COG3063  84 RALELDPSALR 94
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 147-289 1.08e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 1.08e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130 147 QRASWIGYAIAYHLLKDYDMALKLLEEFRQTQqvPPNKIDYEYSELILYQNQVMREA-DLLQESLEHIEmyekqicDKLL 225
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEAFALLGEILLQLGDLDEAiVLLHEALELDP-------DEPE 73

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33356130 226 VEEIKGEILLKLGRLKEASEVFKNLIDRNAENWCYYEGLEKALQ-ISTLEERLQIYEEISKQHPK 289
Cdd:COG4783  74 ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRaLGRPDEAIAALEKALELDPD 138
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 60-210 1.69e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 1.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130    60 GKKEEAYEFVRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLE--GYRETR 137
Cdd:TIGR02917 750 GNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRalEYAERA 829

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33356130   138 yqlLQLRPTQRASWIGYAIAYHLLKDYDMALKLLEefRQTQQVPPN-KIDYEYSELILYQNQVMREADLLQESL 210
Cdd:TIGR02917 830 ---LKLAPNIPAILDTLGWLLVEKGEADRALPLLR--KAVNIAPEAaAIRYHLALALLATGRKAEARKELDKLL 898
TPR_1 pfam00515
Tetratricopeptide repeat;
87-113 1.47e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 1.47e-03
                          10        20
                  ....*....|....*....|....*..
gi 33356130    87 GLLQRSDKKYDEAIKCYRNALKLDKDN 113
Cdd:pfam00515   8 GNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 91-253 1.63e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130    91 RSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLKDYDMALKl 170
Cdd:TIGR02917 578 LGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAIT- 656

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   171 leEFRQTQQVPPNkidyeYSELILYQNQVMREADLLQESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250
Cdd:TIGR02917 657 --SLKRALELKPD-----NTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKA 729


                  ...
gi 33356130   251 IDR 253
Cdd:TIGR02917 730 LKR 732
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 83-289 2.44e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130    83 WHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHLLK 162
Cdd:TIGR02917 604 WLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAK 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33356130   163 DYDMALKLLEEFRQTQQVPPNKIDYEYSeliLYqnqvMREADLLQESLEHIEMYEKQICDKLLVEeiKGEILLKLGRLKE 242
Cdd:TIGR02917 684 RTESAKKIAKSLQKQHPKAALGFELEGD---LY----LRQKDYPAAIQAYRKALKRAPSSQNAIK--LHRALLASGNTAE 754

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 33356130   243 ASEVFKNLIDRNAENWC--YYEGlEKALQISTLEERLQIYEEISKQHPK 289
Cdd:TIGR02917 755 AVKTLEAWLKTHPNDAVlrTALA-ELYLAQKDYDKAIKHYQTVVKKAPD 802
TPR_11 pfam13414
TPR repeat;
95-127 6.68e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 33.98  E-value: 6.68e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 33356130    95 KYDEAIKCYRNALKLDKDNLQILRDLSLLQIQM 127
Cdd:pfam13414   9 KYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 87-113 7.76e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.57  E-value: 7.76e-03
                           10        20
                   ....*....|....*....|....*..
gi 33356130     87 GLLQRSDKKYDEAIKCYRNALKLDKDN 113
Cdd:smart00028   8 GNAYLKLGDYDEALEYYEKALELDPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
44-115 9.60e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 35.15  E-value: 9.60e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33356130  44 EHGETLAMKGLTLNCLGKKEEAYEFvRKGLRNDVKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKLDKDNLQ 115
Cdd:COG3063  24 DNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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