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Conserved domains on  [gi|13259376|ref|NP_077172|]
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multiple myeloma tumor-associated protein 2 homolog [Mus musculus]

Protein Classification

MMtag domain-containing protein( domain architecture ID 10562706)

MMtag domain-containing protein similar to human multiple myeloma tumor-associated protein 2 (hMMTAG2)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MMtag pfam10159
Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly ...
8-83 1.02e-36

Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly conserved region of a family of proteins that in vertebrates are associated with tumours in multiple myelomas. The region may contain nuclear localization signals, so it might act as a signal molecule in the nucleus.


:

Pssm-ID: 431097  Cd Length: 78  Bit Score: 124.61  E-value: 1.02e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13259376     8 GVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKDRAPCTGPS--REEELAAVREAEREALLAALG 83
Cdd:pfam10159   1 GSRGGRDQFKWEDVKSSKHRENYLGHSLMAPVGRWQKGKDLDWYAKGDDDADEAEeeRKEEIRRIKEAEEEALAEALG 78
 
Name Accession Description Interval E-value
MMtag pfam10159
Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly ...
8-83 1.02e-36

Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly conserved region of a family of proteins that in vertebrates are associated with tumours in multiple myelomas. The region may contain nuclear localization signals, so it might act as a signal molecule in the nucleus.


Pssm-ID: 431097  Cd Length: 78  Bit Score: 124.61  E-value: 1.02e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13259376     8 GVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKDRAPCTGPS--REEELAAVREAEREALLAALG 83
Cdd:pfam10159   1 GSRGGRDQFKWEDVKSSKHRENYLGHSLMAPVGRWQKGKDLDWYAKGDDDADEAEeeRKEEIRRIKEAEEEALAEALG 78
 
Name Accession Description Interval E-value
MMtag pfam10159
Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly ...
8-83 1.02e-36

Multiple myeloma tumor-associated; This is a glycine-rich domain that is the most highly conserved region of a family of proteins that in vertebrates are associated with tumours in multiple myelomas. The region may contain nuclear localization signals, so it might act as a signal molecule in the nucleus.


Pssm-ID: 431097  Cd Length: 78  Bit Score: 124.61  E-value: 1.02e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13259376     8 GVRGGQDQFNWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKDRAPCTGPS--REEELAAVREAEREALLAALG 83
Cdd:pfam10159   1 GSRGGRDQFKWEDVKSSKHRENYLGHSLMAPVGRWQKGKDLDWYAKGDDDADEAEeeRKEEIRRIKEAEEEALAEALG 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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