NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|58037131|ref|NP_081149|]
View 

pentatricopeptide repeat-containing protein 2, mitochondrial [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MRP-S27 super family cl25450
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
 128-205 6.26e-06

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


The actual alignment was detected with superfamily member pfam10037:

Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 47.82  E-value: 6.26e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58037131   128 VFMRLCYELDLEDSAVELVRDKHLQGFFLDSTSFNILMDMLFTKGKYERALQVLIEMKNQDVrFSKE-TYILAFAICYK 205
Cdd:pfam10037 110 AWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSAASVVTELMLQEA-FDNPsTQLLSLYSCYK 187
PLN03218 super family cl33664
maturation of RBCL 1; Provisional
 159-269 4.46e-03

maturation of RBCL 1; Provisional


The actual alignment was detected with superfamily member PLN03218:

Pssm-ID: 215636 [Multi-domain]  Cd Length: 1060  Bit Score: 39.09  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037131   159 TSFNILMDMLFTKGKYERALQVLIEMKNQDVRFSKETYILAFAICYKLNTLE-SLKICTTLREEALIKGDIICRrayCFV 237
Cdd:PLN03218  720 STMNALITALCEGNQLPKALEVLSEMKRLGLCPNTITYSILLVASERKDDADvGLDLLSQAKEDGIKPNLVMCR---CIT 796

                          90       100       110
                  ....*....|....*....|....*....|..
gi 58037131   238 valALNKNQLKNAVSIfsqivnPESIVCINLN 269
Cdd:PLN03218  797 ---GLCLRRFEKACAL------GEPVVSFDSG 819
 
Name Accession Description Interval E-value
MRP-S27 pfam10037
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
 128-205 6.26e-06

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 47.82  E-value: 6.26e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58037131   128 VFMRLCYELDLEDSAVELVRDKHLQGFFLDSTSFNILMDMLFTKGKYERALQVLIEMKNQDVrFSKE-TYILAFAICYK 205
Cdd:pfam10037 110 AWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSAASVVTELMLQEA-FDNPsTQLLSLYSCYK 187
PLN03218 PLN03218
maturation of RBCL 1; Provisional
 159-269 4.46e-03

maturation of RBCL 1; Provisional


Pssm-ID: 215636 [Multi-domain]  Cd Length: 1060  Bit Score: 39.09  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037131   159 TSFNILMDMLFTKGKYERALQVLIEMKNQDVRFSKETYILAFAICYKLNTLE-SLKICTTLREEALIKGDIICRrayCFV 237
Cdd:PLN03218  720 STMNALITALCEGNQLPKALEVLSEMKRLGLCPNTITYSILLVASERKDDADvGLDLLSQAKEDGIKPNLVMCR---CIT 796

                          90       100       110
                  ....*....|....*....|....*....|..
gi 58037131   238 valALNKNQLKNAVSIfsqivnPESIVCINLN 269
Cdd:PLN03218  797 ---GLCLRRFEKACAL------GEPVVSFDSG 819
 
Name Accession Description Interval E-value
MRP-S27 pfam10037
Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins ...
 128-205 6.26e-06

Mitochondrial 28S ribosomal protein S27; Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.


Pssm-ID: 462947 [Multi-domain]  Cd Length: 395  Bit Score: 47.82  E-value: 6.26e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58037131   128 VFMRLCYELDLEDSAVELVRDKHLQGFFLDSTSFNILMDMLFTKGKYERALQVLIEMKNQDVrFSKE-TYILAFAICYK 205
Cdd:pfam10037 110 AWIRQCLKYGAPDKALYTLKNKVQYGIFPDNFTFNLLMDSFLKNGDYKSAASVVTELMLQEA-FDNPsTQLLSLYSCYK 187
PPR_2 pfam13041
PPR repeat family; This repeat has no known function. It is about 35 amino acids long and is ...
 157-196 4.07e-04

PPR repeat family; This repeat has no known function. It is about 35 amino acids long and is found in up to 18 copies in some proteins. The family appears to be greatly expanded in plants and fungi. The repeat has been called PPR.


Pssm-ID: 463778 [Multi-domain]  Cd Length: 50  Bit Score: 37.73  E-value: 4.07e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 58037131   157 DSTSFNILMDMLFTKGKYERALQVLIEMKNQDVRFSKETY 196
Cdd:pfam13041   2 DVVTYNTLINGYCKKGKVEEAFKLFNEMKKRGVKPNVYTY 41
PLN03218 PLN03218
maturation of RBCL 1; Provisional
 159-269 4.46e-03

maturation of RBCL 1; Provisional


Pssm-ID: 215636 [Multi-domain]  Cd Length: 1060  Bit Score: 39.09  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037131   159 TSFNILMDMLFTKGKYERALQVLIEMKNQDVRFSKETYILAFAICYKLNTLE-SLKICTTLREEALIKGDIICRrayCFV 237
Cdd:PLN03218  720 STMNALITALCEGNQLPKALEVLSEMKRLGLCPNTITYSILLVASERKDDADvGLDLLSQAKEDGIKPNLVMCR---CIT 796

                          90       100       110
                  ....*....|....*....|....*....|..
gi 58037131   238 valALNKNQLKNAVSIfsqivnPESIVCINLN 269
Cdd:PLN03218  797 ---GLCLRRFEKACAL------GEPVVSFDSG 819
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH