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arrestin domain-containing protein 2 [Mus musculus]
arrestin family protein( domain architecture ID 10448464)
arrestin family protein with both N-terminal and C-terminal Ig-like beta-sandwich domains found in arrestin (S antigen); similar to Homo sapiens beta-arrestin-1 and arrestin domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
9-158 | 3.36e-48 | |||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. : Pssm-ID: 425619 Cd Length: 148 Bit Score: 160.92 E-value: 3.36e-48
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
180-307 | 1.47e-30 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. : Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 114.36 E-value: 1.47e-30
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Name | Accession | Description | Interval | E-value | |||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
9-158 | 3.36e-48 | |||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. Pssm-ID: 425619 Cd Length: 148 Bit Score: 160.92 E-value: 3.36e-48
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
180-307 | 1.47e-30 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 114.36 E-value: 1.47e-30
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Arrestin_C | pfam02752 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
180-307 | 1.41e-28 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Pssm-ID: 460676 Cd Length: 135 Bit Score: 108.95 E-value: 1.41e-28
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ART10-like | cd22952 | Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking ... |
98-138 | 6.30e-05 | |||
Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking adaptors (ARTs) function by targeting specific plasma membrane proteins to the endocytic system. They contain multiple PY motifs that are required for recruitment of Rsp5/Nedd4-like ubiquitin ligase which modifies the cargoes. It has been proposed that ARTs remodel the cell surface in response to environmental cues and may serve as part of a quality-control system at the plasma membrane, targeting damaged and misfolded membrane proteins for ubiquitination and subsequent degradation in the lysosome/vacuole. The specific target protein for ART10 is not yet known. Pssm-ID: 438568 [Multi-domain] Cd Length: 409 Bit Score: 44.66 E-value: 6.30e-05
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Name | Accession | Description | Interval | E-value | |||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
9-158 | 3.36e-48 | |||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. Pssm-ID: 425619 Cd Length: 148 Bit Score: 160.92 E-value: 3.36e-48
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
180-307 | 1.47e-30 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 114.36 E-value: 1.47e-30
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Arrestin_C | pfam02752 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
180-307 | 1.41e-28 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Pssm-ID: 460676 Cd Length: 135 Bit Score: 108.95 E-value: 1.41e-28
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ART10-like | cd22952 | Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking ... |
98-138 | 6.30e-05 | |||
Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking adaptors (ARTs) function by targeting specific plasma membrane proteins to the endocytic system. They contain multiple PY motifs that are required for recruitment of Rsp5/Nedd4-like ubiquitin ligase which modifies the cargoes. It has been proposed that ARTs remodel the cell surface in response to environmental cues and may serve as part of a quality-control system at the plasma membrane, targeting damaged and misfolded membrane proteins for ubiquitination and subsequent degradation in the lysosome/vacuole. The specific target protein for ART10 is not yet known. Pssm-ID: 438568 [Multi-domain] Cd Length: 409 Bit Score: 44.66 E-value: 6.30e-05
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Blast search parameters | ||||
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