![](files/infoQ.gif)
caspase-1 isoform epsilon [Homo sapiens]
caspase family protein( domain architecture ID 1724)
caspase family protein similar to caspases which are cysteine class enzymes that drive the terminal stages of apoptosis as well as other cellular remodeling and inflammatory events
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | ||
CASc super family | cl00042 | Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent ... |
13-86 | 3.26e-29 | ||
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide backbone adjacent to an aspartate. The resulting two subunits associate to form an (alpha)2(beta)2-tetramer which is the active enzyme. Activation of caspases can be mediated by other caspase homologs. The actual alignment was detected with superfamily member smart00115: Pssm-ID: 444667 Cd Length: 241 Bit Score: 103.86 E-value: 3.26e-29
|
||||||
Name | Accession | Description | Interval | E-value | |||
CASc | smart00115 | Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine aspartases that ... |
13-86 | 3.26e-29 | |||
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine aspartases that mediate programmed cell death (apoptosis). Caspases are synthesised as zymogens and activated by proteolysis of the peptide backbone adjacent to an aspartate. The resulting two subunits associate to form an (alpha)2(beta)2-tetramer which is the active enzyme. Activation of caspases can be mediated by other caspase homologues. Pssm-ID: 214521 Cd Length: 241 Bit Score: 103.86 E-value: 3.26e-29
|
|||||||
CASc | cd00032 | Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent ... |
13-85 | 1.11e-22 | |||
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide backbone adjacent to an aspartate. The resulting two subunits associate to form an (alpha)2(beta)2-tetramer which is the active enzyme. Activation of caspases can be mediated by other caspase homologs. Pssm-ID: 237997 Cd Length: 243 Bit Score: 87.27 E-value: 1.11e-22
|
|||||||
Peptidase_C14 | pfam00656 | Caspase domain; |
3-83 | 5.01e-22 | |||
Caspase domain; Pssm-ID: 425803 Cd Length: 213 Bit Score: 84.68 E-value: 5.01e-22
|
|||||||
Name | Accession | Description | Interval | E-value | |||
CASc | smart00115 | Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine aspartases that ... |
13-86 | 3.26e-29 | |||
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine aspartases that mediate programmed cell death (apoptosis). Caspases are synthesised as zymogens and activated by proteolysis of the peptide backbone adjacent to an aspartate. The resulting two subunits associate to form an (alpha)2(beta)2-tetramer which is the active enzyme. Activation of caspases can be mediated by other caspase homologues. Pssm-ID: 214521 Cd Length: 241 Bit Score: 103.86 E-value: 3.26e-29
|
|||||||
CASc | cd00032 | Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent ... |
13-85 | 1.11e-22 | |||
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide backbone adjacent to an aspartate. The resulting two subunits associate to form an (alpha)2(beta)2-tetramer which is the active enzyme. Activation of caspases can be mediated by other caspase homologs. Pssm-ID: 237997 Cd Length: 243 Bit Score: 87.27 E-value: 1.11e-22
|
|||||||
Peptidase_C14 | pfam00656 | Caspase domain; |
3-83 | 5.01e-22 | |||
Caspase domain; Pssm-ID: 425803 Cd Length: 213 Bit Score: 84.68 E-value: 5.01e-22
|
|||||||
Blast search parameters | ||||
|