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Conserved domains on  [gi|63079709|ref|NP_443200|]
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apolipoprotein A-V precursor [Homo sapiens]

Protein Classification

apolipoprotein A1/A4/E family protein( domain architecture ID 12019813)

apolipoprotein A1/A4/E family protein associates with lipid particles and may function in lipoprotein-mediated lipid transport

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
59-247 1.26e-36

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


:

Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 130.46  E-value: 1.26e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709    59 SLEQDLNNMNKFLEKLR----PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTM 134
Cdd:pfam01442   1 LLEDSLDELSTYAEELQeqlgPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709   135 DLMEQVALRVQELQEQLRVVGEdtkaqllggvdeawallqGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 214
Cdd:pfam01442  81 ELRKRLNADAEELQEKLAPYGE------------------ELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLA 142
                         170       180       190
                  ....*....|....*....|....*....|...
gi 63079709   215 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQ 247
Cdd:pfam01442 143 PYAEEVQAQLSQRLQELREKLEPQAEDLREKLD 175
 
Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
59-247 1.26e-36

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 130.46  E-value: 1.26e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709    59 SLEQDLNNMNKFLEKLR----PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTM 134
Cdd:pfam01442   1 LLEDSLDELSTYAEELQeqlgPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709   135 DLMEQVALRVQELQEQLRVVGEdtkaqllggvdeawallqGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 214
Cdd:pfam01442  81 ELRKRLNADAEELQEKLAPYGE------------------ELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLA 142
                         170       180       190
                  ....*....|....*....|....*....|...
gi 63079709   215 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQ 247
Cdd:pfam01442 143 PYAEEVQAQLSQRLQELREKLEPQAEDLREKLD 175
 
Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
59-247 1.26e-36

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 130.46  E-value: 1.26e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709    59 SLEQDLNNMNKFLEKLR----PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTM 134
Cdd:pfam01442   1 LLEDSLDELSTYAEELQeqlgPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 63079709   135 DLMEQVALRVQELQEQLRVVGEdtkaqllggvdeawallqGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 214
Cdd:pfam01442  81 ELRKRLNADAEELQEKLAPYGE------------------ELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLA 142
                         170       180       190
                  ....*....|....*....|....*....|...
gi 63079709   215 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQ 247
Cdd:pfam01442 143 PYAEEVQAQLSQRLQELREKLEPQAEDLREKLD 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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