|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
128-312 |
5.19e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 117.34 E-value: 5.19e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 128 EALDGLGSLRRLELEGNALEELrPGTFGALGALATLNLAHNALVYLPAmAFQGLLRVRWLRLSHNALSVLaPEALAGLPA 207
Cdd:COG4886 107 EELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTN 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 208 LRRLSLHHNELQALPGPvLSQARGLARLELGHNPLTYAGEEdgLA-LPGLRELLLDGGALQALgpRAFAHCPRLHTLDLR 286
Cdd:COG4886 184 LKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEP--LAnLTNLETLDLSNNQLTDL--PELGNLTNLEELDLS 258
|
170 180
....*....|....*....|....*.
gi 194440719 287 GNQLDTLPPLQGPGQLRRLRLQGNPL 312
Cdd:COG4886 259 NNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
445-677 |
4.38e-25 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 108.48 E-value: 4.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 445 FPGLGHLVSLHLQHCGiaeleagALAGLGRLIYLYLSDNQLAGLSAAaLEGAPRLGYLYLERNRFLQVPgAALRALPSLF 524
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 525 SLHLQDNAVDRLaPGDLGRTRALRWVYLSGNRITEVSLgALGPARELEKLHLDRNQLREVPTgALEGLPALLELQLSGNP 604
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 194440719 605 LRALRdgafqpvgrSLQHLflnssgleqicpgafsglgPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPF 677
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
498-696 |
5.69e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 5.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 498 RLGYLYLERNRFLQVPGaaLRALPSLFSLHLQDNAVDRLApgDLGRTRALRWVYLSGNRITEvsLGALGPARELEKLHLD 577
Cdd:cd21340 3 RITHLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--IENLENLVNLKKLYLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 578 RNQLREVpTGaLEGLPALLELQLSGnplralrdgafqpvgrslQHLFLNssglEQIC--PGAFSGLGPGLQSLHLQKNQL 655
Cdd:cd21340 77 GNRISVV-EG-LENLTNLEELHIEN------------------QRLPPG----EKLTfdPRSLAALSNSLRVLNISGNNI 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 194440719 656 RALPALPSLSQLELIDLSSNP---FHCDCQLLPLHRWLTGLNLR 696
Cdd:cd21340 133 DSLEPLAPLRNLEQLDASNNQisdLEELLDLLSSWPSLRELDLT 176
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
160-218 |
1.44e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 60.23 E-value: 1.44e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 194440719 160 LATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNEL 218
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
450-509 |
7.38e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 7.38e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 450 HLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRF 509
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
65-146 |
1.24e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 65 QRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNHLRELPQEALDGLGSLRRLELEGN 144
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSN------------------------NLLTTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 194440719 145 AL 146
Cdd:pfam13855 60 RL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
119-295 |
1.24e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.55 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 119 SNHLRELPqEALDGlgSLRRLELEGNALEELrPGTFGalGALATLNLAHNALVYLP---AMAFQGLLrvrwlrLSHNALS 195
Cdd:PRK15370 208 NNELKSLP-ENLQG--NIKTLYANSNQLTSI-PATLP--DTIQEMELSINRITELPerlPSALQSLD------LFHNKIS 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 196 VLaPEALAglPALRRLSLHHNELQALPGPVLSqarGLARLELGHNPLTYAGEedglALP-GLRELLLDGGALQALgPRAF 274
Cdd:PRK15370 276 CL-PENLP--EELRYLSVYDNSIRTLPAHLPS---GITHLNVQSNSLTALPE----TLPpGLKTLEAGENALTSL-PASL 344
|
170 180
....*....|....*....|....*
gi 194440719 275 AhcPRLHTLDLRGNQL----DTLPP 295
Cdd:PRK15370 345 P--PELQVLDVSKNQItvlpETLPP 367
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
67-222 |
1.70e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.56 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 67 LDLQGNLLKVIPAaaFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNHLRELpqEALDGLGSLRRLELEGN-- 144
Cdd:cd21340 29 LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQIEKI--ENLENLVNLKKLYLGGNri 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 145 ----------ALEELR---------------PGTFGALGA-LATLNLAHNALVYLpaMAFQGLLRVRWLRLSHNALSVLA 198
Cdd:cd21340 81 svveglenltNLEELHienqrlppgekltfdPRSLAALSNsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLE 158
|
170 180
....*....|....*....|....*.
gi 194440719 199 P--EALAGLPALRRLSLHHNELQALP 222
Cdd:cd21340 159 EllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
675-723 |
3.16e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 47.42 E-value: 3.16e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 194440719 675 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPNARGQRVKAAAAVFeDCP 723
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGPLLELLHSEF-KCP 51
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
425-675 |
9.31e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.54 E-value: 9.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 425 SDTQLLDLRRNHFP-SVPRAAFPGLGHLVSLHLQHCGIAELEAGALAglgRLIYLYLSDNQLAGLSAAALEGAPRLGYLY 503
Cdd:PLN00113 118 SSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFS---SLKVLDLGGNVLVGKIPNSLTNLTSLEFLT 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 504 LERNRFL-QVPgAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLR 582
Cdd:PLN00113 195 LASNQLVgQIP-RELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 583 EVPTGALEGLPALLELQLSGNPLRA-LRDGAFQPVGRSLQHLFLNSsgLEQICPGAFSGLgPGLQSLHLQKNQLRA-LPA 660
Cdd:PLN00113 274 GPIPPSIFSLQKLISLDLSDNSLSGeIPELVIQLQNLEILHLFSNN--FTGKIPVALTSL-PRLQVLQLWSNKFSGeIPK 350
|
250
....*....|....*.
gi 194440719 661 -LPSLSQLELIDLSSN 675
Cdd:PLN00113 351 nLGKHNNLTVLDLSTN 366
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
664-710 |
1.57e-06 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 52.01 E-value: 1.57e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 194440719 664 LSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPNARGQ 710
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
395-429 |
2.66e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 36.14 E-value: 2.66e-03
10 20 30
....*....|....*....|....*....|....*
gi 194440719 395 PCPRACVCVPesRHSSCEGCGLQAVPRGFPSDTQL 429
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
33-65 |
3.67e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 3.67e-03
10 20 30
....*....|....*....|....*....|...
gi 194440719 33 CPQACICdnSRRHVACRYQNLTEVPDAIPELTQ 65
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
128-312 |
5.19e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 117.34 E-value: 5.19e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 128 EALDGLGSLRRLELEGNALEELrPGTFGALGALATLNLAHNALVYLPAmAFQGLLRVRWLRLSHNALSVLaPEALAGLPA 207
Cdd:COG4886 107 EELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTN 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 208 LRRLSLHHNELQALPGPvLSQARGLARLELGHNPLTYAGEEdgLA-LPGLRELLLDGGALQALgpRAFAHCPRLHTLDLR 286
Cdd:COG4886 184 LKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEP--LAnLTNLETLDLSNNQLTDL--PELGNLTNLEELDLS 258
|
170 180
....*....|....*....|....*.
gi 194440719 287 GNQLDTLPPLQGPGQLRRLRLQGNPL 312
Cdd:COG4886 259 NNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
125-312 |
9.49e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 110.79 E-value: 9.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 125 LPQEALDGLGSLRRLELEGNAleelrpgTFGALGALATLNLAHNALVYLPAmAFQGLLRVRWLRLSHNALSVLaPEALAG 204
Cdd:COG4886 87 LGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL-PEPLGN 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 205 LPALRRLSLHHNELQALPGPvLSQARGLARLELGHNPLTYAGEEdgLA-LPGLRELLLDGGALQALgPRAFAHCPRLHTL 283
Cdd:COG4886 158 LTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQITDLPEP--LGnLTNLEELDLSGNQLTDL-PEPLANLTNLETL 233
|
170 180
....*....|....*....|....*....
gi 194440719 284 DLRGNQLDTLPPLQGPGQLRRLRLQGNPL 312
Cdd:COG4886 234 DLSNNQLTDLPELGNLTNLEELDLSNNQL 262
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
445-677 |
4.38e-25 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 108.48 E-value: 4.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 445 FPGLGHLVSLHLQHCGiaeleagALAGLGRLIYLYLSDNQLAGLSAAaLEGAPRLGYLYLERNRFLQVPgAALRALPSLF 524
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 525 SLHLQDNAVDRLaPGDLGRTRALRWVYLSGNRITEVSLgALGPARELEKLHLDRNQLREVPTgALEGLPALLELQLSGNP 604
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 194440719 605 LRALRdgafqpvgrSLQHLflnssgleqicpgafsglgPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPF 677
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
425-675 |
8.51e-25 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 107.71 E-value: 8.51e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 425 SDTQLLDLRRNHFPSVPrAAFPGLGHLVSLHLQHCGIAELEAgALAGLGRLIYLYLSDNQLAGLSAAaLEGAPRLGYLYL 504
Cdd:COG4886 113 TNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 505 ERNRFLQVPgAALRALPSLFSLHLQDNAVDRLaPGDLGRTRALRWVYLSGNRITevSLGALGPARELEKLHLDRNQLREV 584
Cdd:COG4886 190 SNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLT--DLPELGNLTNLEELDLSNNQLTDL 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 585 PTgaLEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSL 664
Cdd:COG4886 266 PP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343
|
250
....*....|.
gi 194440719 665 SQLELIDLSSN 675
Cdd:COG4886 344 LSLLALLTLLL 354
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
67-293 |
6.98e-24 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 105.02 E-value: 6.98e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 67 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEvelvaegAFRGLGRLLLLNLASNHLRELPqEALDGLGSLRRLELEGNAL 146
Cdd:COG4886 77 LSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 147 EELrPGTFGALGALATLNLAHNALVYLPAmAFQGLLRVRWLRLSHNALSVLaPEALAGLPALRRLSLHHNELQALPGPvL 226
Cdd:COG4886 149 TDL-PEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEP-L 224
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 194440719 227 SQARGLARLELGHNPLTYAGEedgLA-LPGLRELLLDGGALQALGPraFAHCPRLHTLDLRGNQLDTL 293
Cdd:COG4886 225 ANLTNLETLDLSNNQLTDLPE---LGnLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDL 287
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
52-271 |
1.92e-23 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 103.86 E-value: 1.92e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 52 NLTEVPDAIPELT--QRLDLQGNLLKVIPAAaFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNHLRELPqEA 129
Cdd:COG4886 124 QLTDLPEELANLTnlKELDLSNNQLTDLPEP-LGNLTNLKSLDLSN------------------------NQLTDLP-EE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 130 LDGLGSLRRLELEGNALEELrPGTFGALGALATLNLAHNALVYLPAmAFQGLLRVRWLRLSHNALSVLapEALAGLPALR 209
Cdd:COG4886 178 LGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLTDL--PELGNLTNLE 253
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194440719 210 RLSLHHNELQALPgpVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGP 271
Cdd:COG4886 254 ELDLSNNQLTDLP--PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLEL 313
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
461-677 |
9.27e-23 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 101.55 E-value: 9.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 461 IAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQvpgaalrALPSLFSLHLQDNAVDRLaPGD 540
Cdd:COG4886 60 LLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELS-------NLTNLESLDLSGNQLTDL-PEE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 541 LGRTRALRWVYLSGNRITEVSLgALGPARELEKLHLDRNQLREVPTgALEGLPALLELQLSGNPLRALRDgafqPVGR-- 618
Cdd:COG4886 132 LANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPE----PLGNlt 205
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 194440719 619 SLQHLFLNSSGLEQIcPGAFSGLgPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPF 677
Cdd:COG4886 206 NLEELDLSGNQLTDL-PEPLANL-TNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQL 262
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
44-262 |
5.01e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 5.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 44 RHVACRYQNLTEVPDAIPELT--QRLDLQGNLLKVIPAAaFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNH 121
Cdd:COG4886 139 KELDLSNNQLTDLPEPLGNLTnlKSLDLSNNQLTDLPEE-LGNLTNLKELDLSN------------------------NQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 122 LRELPqEALDGLGSLRRLELEGNALEELrPGTFGALGALATLNLAHNALVYLPAMAfqGLLRVRWLRLSHNALSVLAPea 201
Cdd:COG4886 194 ITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPELG--NLTNLEELDLSNNQLTDLPP-- 267
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194440719 202 LAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLD 262
Cdd:COG4886 268 LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLL 328
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
410-672 |
8.44e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.44 E-value: 8.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 410 SCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPrAAFPGLGHLVSLHLQHCGIAELEAgALAGLGRLIYLYLSDNQLAG 487
Cdd:COG4886 142 DLSNNQLTDLPEPLGNLTNLksLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTD 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 488 LSAAaLEGAPRLGYLYLERNRFLQVPgaALRALPSLFSLHLQDNAVDRLAPgdLGRTRALRWVYLSGNRITEVSLGALGP 567
Cdd:COG4886 220 LPEP-LANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELEL 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 568 ARELEKLHLDRNQL--REVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGL 645
Cdd:COG4886 295 LLGLNSLLLLLLLLnlLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGL 374
|
250 260
....*....|....*....|....*..
gi 194440719 646 QSLHLQKNQLRALPALPSLSQLELIDL 672
Cdd:COG4886 375 LEATLLTLALLLLTLLLLLLTTTAGVL 401
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
498-696 |
5.69e-15 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 5.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 498 RLGYLYLERNRFLQVPGaaLRALPSLFSLHLQDNAVDRLApgDLGRTRALRWVYLSGNRITEvsLGALGPARELEKLHLD 577
Cdd:cd21340 3 RITHLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--IENLENLVNLKKLYLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 578 RNQLREVpTGaLEGLPALLELQLSGnplralrdgafqpvgrslQHLFLNssglEQIC--PGAFSGLGPGLQSLHLQKNQL 655
Cdd:cd21340 77 GNRISVV-EG-LENLTNLEELHIEN------------------QRLPPG----EKLTfdPRSLAALSNSLRVLNISGNNI 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 194440719 656 RALPALPSLSQLELIDLSSNP---FHCDCQLLPLHRWLTGLNLR 696
Cdd:cd21340 133 DSLEPLAPLRNLEQLDASNNQisdLEELLDLLSSWPSLRELDLT 176
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
430-605 |
1.40e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 67.50 E-value: 1.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 430 LDLRRNHFPSVPraAFPGLGHLVSLHLQHCGIAELEAgaLAGLGRLIYLYLSDNQLAGLSAaaLEGAPRLGYLYLERNRf 509
Cdd:cd21340 29 LYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVVEG--LENLTNLEELHIENQR- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 510 lqvpgaalraLPSLFSLHLQDNAVDRLAPgdlgrtrALRWVYLSGNRITevSLGALGPARELEKLHLDRNQLREVP--TG 587
Cdd:cd21340 102 ----------LPPGEKLTFDPRSLAALSN-------SLRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISDLEelLD 162
|
170
....*....|....*...
gi 194440719 588 ALEGLPALLELQLSGNPL 605
Cdd:cd21340 163 LLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
160-218 |
1.44e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 60.23 E-value: 1.44e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 194440719 160 LATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNEL 218
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
135-194 |
1.06e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.53 E-value: 1.06e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 135 SLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNAL 194
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
254-312 |
5.84e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 5.84e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194440719 254 PGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPP--LQGPGQLRRLRLQGNPL 312
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
450-509 |
7.38e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 7.38e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 450 HLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRF 509
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
569-630 |
1.11e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.11e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194440719 569 RELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVgRSLQHLFLNSSGL 630
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
65-146 |
1.24e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 65 QRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNHLRELPQEALDGLGSLRRLELEGN 144
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSN------------------------NLLTTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 194440719 145 AL 146
Cdd:pfam13855 60 RL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
119-295 |
1.24e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.55 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 119 SNHLRELPqEALDGlgSLRRLELEGNALEELrPGTFGalGALATLNLAHNALVYLP---AMAFQGLLrvrwlrLSHNALS 195
Cdd:PRK15370 208 NNELKSLP-ENLQG--NIKTLYANSNQLTSI-PATLP--DTIQEMELSINRITELPerlPSALQSLD------LFHNKIS 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 196 VLaPEALAglPALRRLSLHHNELQALPGPVLSqarGLARLELGHNPLTYAGEedglALP-GLRELLLDGGALQALgPRAF 274
Cdd:PRK15370 276 CL-PENLP--EELRYLSVYDNSIRTLPAHLPS---GITHLNVQSNSLTALPE----TLPpGLKTLEAGENALTSL-PASL 344
|
170 180
....*....|....*....|....*
gi 194440719 275 AhcPRLHTLDLRGNQL----DTLPP 295
Cdd:PRK15370 345 P--PELQVLDVSKNQItvlpETLPP 367
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
67-222 |
1.70e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.56 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 67 LDLQGNLLKVIPAaaFQGVPHLTHLDLRHcevelvaegafrglgrllllnlasNHLRELpqEALDGLGSLRRLELEGN-- 144
Cdd:cd21340 29 LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQIEKI--ENLENLVNLKKLYLGGNri 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 145 ----------ALEELR---------------PGTFGALGA-LATLNLAHNALVYLpaMAFQGLLRVRWLRLSHNALSVLA 198
Cdd:cd21340 81 svveglenltNLEELHienqrlppgekltfdPRSLAALSNsLRVLNISGNNIDSL--EPLAPLRNLEQLDASNNQISDLE 158
|
170 180
....*....|....*....|....*.
gi 194440719 199 P--EALAGLPALRRLSLHHNELQALP 222
Cdd:cd21340 159 EllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
183-242 |
1.93e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.93e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 183 RVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPL 242
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
545-605 |
2.46e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.99 E-value: 2.46e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194440719 545 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPL 605
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
453-631 |
8.19e-08 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 55.18 E-value: 8.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 453 SLHLQHCGIAELEA----GALAGLGRLIYLYLSDNQL--AGLSAAA--LEGAPRLGYLYLERNRfLQVPGA-----ALRA 519
Cdd:COG5238 212 TLWLKRNPIGDEGAeilaEALKGNKSLTTLDLSNNQIgdEGVIALAeaLKNNTTVETLYLSGNQ-IGAEGAialakALQG 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 520 LPSLFSLHLQDN-----AVDRLAPGdLGRTRALRWVYLSGNRITEVSLGALGPARE----LEKLHLDRNQLR----EVPT 586
Cdd:COG5238 291 NTTLTSLDLSVNrigdeGAIALAEG-LQGNKTLHTLNLAYNGIGAQGAIALAKALQenttLHSLDLSDNQIGdegaIALA 369
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 194440719 587 GALEGLPALLELQLSGNplrALRDGAFQPVGRSLQHLFLNSSGLE 631
Cdd:COG5238 370 KYLEGNTTLRELNLGKN---NIGKQGAEALIDALQTNRLHTLILD 411
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
119-170 |
1.63e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 1.63e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 194440719 119 SNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNAL 170
Cdd:pfam13855 10 NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
618-677 |
2.30e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 2.30e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194440719 618 RSLQHLFLNSSGLEQICPGAFSGLgPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSNPF 677
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGL-SNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
497-557 |
2.69e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 2.69e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194440719 497 PRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRI 557
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
675-723 |
3.16e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 47.42 E-value: 3.16e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 194440719 675 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPNARGQRVKAAAAVFeDCP 723
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGPLLELLHSEF-KCP 51
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
118-290 |
3.90e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.70 E-value: 3.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 118 ASNHLR-ELPqEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSV 196
Cdd:PLN00113 364 STNNLTgEIP-EGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQG 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 197 LAPEALAGLPALRRLSLHHNE-LQALPGpvLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFA 275
Cdd:PLN00113 443 RINSRKWDMPSLQMLSLARNKfFGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELS 520
|
170
....*....|....*
gi 194440719 276 HCPRLHTLDLRGNQL 290
Cdd:PLN00113 521 SCKKLVSLDLSHNQL 535
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
44-312 |
6.83e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.78 E-value: 6.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 44 RHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPaaafQGVPH-LTHLDLRHcevelvaegafrglgrllllnlasNHL 122
Cdd:PRK15370 223 KTLYANSNQLTSIPATLPDTIQEMELSINRITELP----ERLPSaLQSLDLFH------------------------NKI 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 123 RELPQEALDGLGSLRRLELEGNALEELRPgtfgalGALATLNLAHNALVYLPAMAFQGLlrvRWLRLSHNALSVLaPEAL 202
Cdd:PRK15370 275 SCLPENLPEELRYLSVYDNSIRTLPAHLP------SGITHLNVQSNSLTALPETLPPGL---KTLEAGENALTSL-PASL 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 203 AglPALRRLSLHHNELQALPG---PVLSQarglarLELGHNPLTYAGEEdglaLPglrellldgGALQalgprafahcpr 279
Cdd:PRK15370 345 P--PELQVLDVSKNQITVLPEtlpPTITT------LDVSRNALTNLPEN----LP---------AALQ------------ 391
|
250 260 270
....*....|....*....|....*....|....*...
gi 194440719 280 lhTLDLRGNQL----DTLPPLQGPG-QLRRLRLQGNPL 312
Cdd:PRK15370 392 --IMQASRNNLvrlpESLPHFRGEGpQPTRIIVEYNPF 427
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
425-675 |
9.31e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.54 E-value: 9.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 425 SDTQLLDLRRNHFP-SVPRAAFPGLGHLVSLHLQHCGIAELEAGALAglgRLIYLYLSDNQLAGLSAAALEGAPRLGYLY 503
Cdd:PLN00113 118 SSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFS---SLKVLDLGGNVLVGKIPNSLTNLTSLEFLT 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 504 LERNRFL-QVPgAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLR 582
Cdd:PLN00113 195 LASNQLVgQIP-RELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 583 EVPTGALEGLPALLELQLSGNPLRA-LRDGAFQPVGRSLQHLFLNSsgLEQICPGAFSGLgPGLQSLHLQKNQLRA-LPA 660
Cdd:PLN00113 274 GPIPPSIFSLQKLISLDLSDNSLSGeIPELVIQLQNLEILHLFSNN--FTGKIPVALTSL-PRLQVLQLWSNKFSGeIPK 350
|
250
....*....|....*.
gi 194440719 661 -LPSLSQLELIDLSSN 675
Cdd:PLN00113 351 nLGKHNNLTVLDLSTN 366
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
664-710 |
1.57e-06 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 52.01 E-value: 1.57e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 194440719 664 LSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPNARGQ 710
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
430-485 |
1.75e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 1.75e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 194440719 430 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQL 485
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
200-312 |
2.00e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.40 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 200 EALAGLPALRRLSLHHNELQALPGpvLSQARGLARLELGHNPLTyagEEDGLA-LPGLRELLLDGgalQALGPR------ 272
Cdd:cd21340 40 ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRIS---VVEGLEnLTNLEELHIEN---QRLPPGekltfd 111
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 194440719 273 ---AFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPL 312
Cdd:cd21340 112 prsLAALSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQI 154
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
124-290 |
3.32e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 50.62 E-value: 3.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 124 ELPQEaLDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 203
Cdd:PLN00113 155 EIPND-IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIG 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 204 GLPALRRLSLHHNELQA---------------------LPGPVLSQARGLAR---LELGHNPLTYAGEEDGLALPGLREL 259
Cdd:PLN00113 234 GLTSLNHLDLVYNNLTGpipsslgnlknlqylflyqnkLSGPIPPSIFSLQKlisLDLSDNSLSGEIPELVIQLQNLEIL 313
|
170 180 190
....*....|....*....|....*....|.
gi 194440719 260 LLDGGALQALGPRAFAHCPRLHTLDLRGNQL 290
Cdd:PLN00113 314 HLFSNNFTGKIPVALTSLPRLQVLQLWSNKF 344
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
124-312 |
6.61e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 49.85 E-value: 6.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 124 ELPQEaLDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALV-YLPAMAFqGLLRVRWLRLSHNALSVLAPEAL 202
Cdd:PLN00113 227 EIPYE-IGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIF-SLQKLISLDLSDNSLSGEIPELV 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 203 AGLPALRRLSLHHNELQA-LPGPVLSQARgLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLH 281
Cdd:PLN00113 305 IQLQNLEILHLFSNNFTGkIPVALTSLPR-LQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLF 383
|
170 180 190
....*....|....*....|....*....|...
gi 194440719 282 TLDLRGNQLDT-LPP-LQGPGQLRRLRLQGNPL 312
Cdd:PLN00113 384 KLILFSNSLEGeIPKsLGACRSLRRVRLQDNSF 416
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
124-242 |
1.24e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 49.08 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 124 ELPQeaLDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 203
Cdd:PLN00113 467 GLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFS 544
|
90 100 110
....*....|....*....|....*....|....*....
gi 194440719 204 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPL 242
Cdd:PLN00113 545 EMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
119-290 |
1.70e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 48.31 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 119 SNHLR-ELPQeALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNAL----------------VYLPAMAFQGL 181
Cdd:PLN00113 389 SNSLEgEIPK-SLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLqgrinsrkwdmpslqmLSLARNKFFGG 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 182 L-------RVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTyaGEEdglalp 254
Cdd:PLN00113 468 LpdsfgskRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLS--GQI------ 539
|
170 180 190
....*....|....*....|....*....|....*.
gi 194440719 255 glrellldggalqalgPRAFAHCPRLHTLDLRGNQL 290
Cdd:PLN00113 540 ----------------PASFSEMPVLSQLDLSQNQL 559
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
403-608 |
2.09e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.15 E-value: 2.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 403 VPESRHS-----SCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRaAFPGLghLVSLHLQHCGIAELEAGALAGLGrliY 477
Cdd:PRK15370 214 LPENLQGniktlYANSNQLTSIPATLPDTIQEMELSINRITELPE-RLPSA--LQSLDLFHNKISCLPENLPEELR---Y 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 478 LYLSDNQLAGLSAAALEGaprLGYLYLERNRFLQVPgAALRalPSLFSLHLQDNAVDRLaPGDLgrTRALRWVYLSGNRI 557
Cdd:PRK15370 288 LSVYDNSIRTLPAHLPSG---ITHLNVQSNSLTALP-ETLP--PGLKTLEAGENALTSL-PASL--PPELQVLDVSKNQI 358
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 194440719 558 TeVSLGALGPAreLEKLHLDRNQLREVPtgalEGLPALLE-LQLSGNPLRAL 608
Cdd:PRK15370 359 T-VLPETLPPT--ITTLDVSRNALTNLP----ENLPAALQiMQASRNNLVRL 403
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
521-581 |
2.09e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.51 E-value: 2.09e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194440719 521 PSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQL 581
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
430-677 |
2.18e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 47.92 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 430 LDLRRNHFP-SVPraafPGLGHLVSLH---LQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLE 505
Cdd:PLN00113 241 LDLVYNNLTgPIP----SSLGNLKNLQylfLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLF 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 506 RNRFL-QVPGAaLRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRIT-EVSLG-------------------- 563
Cdd:PLN00113 317 SNNFTgKIPVA-LTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGlcssgnlfklilfsnslege 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 564 ---ALGPARELEKLHLDRNQLR-EVPTGALEgLPALLELQLSGNPLRalrdgafqpvGRslqhlfLNSSGLEQicpgafs 639
Cdd:PLN00113 396 ipkSLGACRSLRRVRLQDNSFSgELPSEFTK-LPLVYFLDISNNNLQ----------GR------INSRKWDM------- 451
|
250 260 270
....*....|....*....|....*....|....*....
gi 194440719 640 glgPGLQSLHLQKNQLRA-LPALPSLSQLELIDLSSNPF 677
Cdd:PLN00113 452 ---PSLQMLSLARNKFFGgLPDSFGSKRLENLDLSRNQF 487
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
561-663 |
6.23e-05 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 46.69 E-value: 6.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 561 SLGALGParELEKLHLDRNQLREVPTGAleglPALLELQLSGNPLRALrdgAFQPVGRSLQHLFLNSSGLEQICPgafsg 640
Cdd:PRK15387 236 SLPALPP--ELRTLEVSGNQLTSLPVLP----PGLLELSIFSNPLTHL---PALPSGLCKLWIFGNQLTSLPVLP----- 301
|
90 100
....*....|....*....|...
gi 194440719 641 lgPGLQSLHLQKNQLRALPALPS 663
Cdd:PRK15387 302 --PGLQELSVSDNQLASLPALPS 322
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
424-603 |
9.93e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.04 E-value: 9.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 424 PSDTQLLDLRRNHFPSVPRA------AFPGLGHLVSLHLQHCGIAELEAGALAGLGR---LIYLYLSDNQLAG----LSA 490
Cdd:cd00116 50 QPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVLESLLRsssLQELKLNNNGLGDrglrLLA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 491 AAL-EGAPRLGYLYLERNRfLQVPGA-----ALRALPSLFSLHLQDNAVD-----RLAPGdLGRTRALRWVYLSGNRITE 559
Cdd:cd00116 130 KGLkDLPPALEKLVLGRNR-LEGASCealakALRANRDLKELNLANNGIGdagirALAEG-LKANCNLEVLDLNNNGLTD 207
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 194440719 560 VSLGALGPA----RELEKLHLDRNQLREVPTGAL-----EGLPALLELQLSGN 603
Cdd:cd00116 208 EGASALAETlaslKSLEVLNLGDNNLTDAGAAALasallSPNISLLTLSLSCN 260
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
118-555 |
1.34e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.61 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 118 ASNHLR-ELPQEaLDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSV 196
Cdd:PLN00113 196 ASNQLVgQIPRE-LGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 197 LAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAH 276
Cdd:PLN00113 275 PIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGK 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 277 CPRLHTLDLRGNQLDTLPP--LQGPGQLRRLRLQGNPLwcGCQARPLLewlararvrsdGACQGPRRLRGEaldalrpwD 354
Cdd:PLN00113 355 HNNLTVLDLSTNNLTGEIPegLCSSGNLFKLILFSNSL--EGEIPKSL-----------GACRSLRRVRLQ--------D 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 355 LRCPGDAAQEEEELEEravagprapprgpprgpgeeravapcpracVCVPESRHSSCEGcGLQAVPRGFPSdTQLLDLRR 434
Cdd:PLN00113 414 NSFSGELPSEFTKLPL------------------------------VYFLDISNNNLQG-RINSRKWDMPS-LQMLSLAR 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 435 NHF-PSVPRaaFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFL-QV 512
Cdd:PLN00113 462 NKFfGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQI 539
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 194440719 513 PgAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGN 555
Cdd:PLN00113 540 P-ASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHN 581
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
130-258 |
2.63e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.42 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 130 LDGLGslrrleLEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALR 209
Cdd:PLN03150 420 IDGLG------LDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLR 493
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 194440719 210 RLSLHHNELQA-LPGPVLSQARGLARLELGHNPltyageedGL-ALPGLRE 258
Cdd:PLN03150 494 ILNLNGNSLSGrVPAALGGRLLHRASFNFTDNA--------GLcGIPGLRA 536
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
445-676 |
3.15e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.50 E-value: 3.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 445 FPGLGHLVSLHLQHCGIAELEAGALAGLGR----LIYLYLSDNQLAGLSAA------ALEGAPRLGYLYLERNRFLQVPG 514
Cdd:cd00116 19 LPKLLCLQVLRLEGNTLGEEAAKALASALRpqpsLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGC 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 515 AALRAL---PSLFSLHLQDNAVDR-----LAPGDLGRTRALRWVYLSGNRITEVSLGALGPA----RELEKLHLDRNQLR 582
Cdd:cd00116 99 GVLESLlrsSSLQELKLNNNGLGDrglrlLAKGLKDLPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNGIG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 583 EvptgalEGLPALLElqlsgnplrALRDGAfqpvgrSLQHLFLNSSGLEQICPGAFSGlgpglqslhlqknqlralpALP 662
Cdd:cd00116 179 D------AGIRALAE---------GLKANC------NLEVLDLNNNGLTDEGASALAE-------------------TLA 218
|
250
....*....|....
gi 194440719 663 SLSQLELIDLSSNP 676
Cdd:cd00116 219 SLKSLEVLNLGDNN 232
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
41-319 |
3.53e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 43.63 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 41 NSRRHVACRYQNL----TEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLN 116
Cdd:COG5238 107 ETATAVATPPPDLrrimAKTLEDSLILYLALPRRINLIQVLKDPLGGNAVHLLGLAARLGLLAAISMAKALQNNSVETVY 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 117 LASNHLR----ELPQEALDGLGSLRRLELEGNALEELRPGTFGALG----ALATLNLAHNALVYLPAMAFQGLLR----V 184
Cdd:COG5238 187 LGCNQIGdegiEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALkgnkSLTTLDLSNNQIGDEGVIALAEALKnnttV 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 185 RWLRLSHNALS----VLAPEALAGLPALRRLSLHHNELQAlPGPV-----LSQARGLARLELGHNPLTYAGEEdGLA--- 252
Cdd:COG5238 267 ETLYLSGNQIGaegaIALAKALQGNTTLTSLDLSVNRIGD-EGAIalaegLQGNKTLHTLNLAYNGIGAQGAI-ALAkal 344
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194440719 253 --LPGLRELLLDGGALQALGPRAFAH----CPRLHTLDLRGNQL------DTLPPLQGpGQLRRLRLQGNPLWCGCQAR 319
Cdd:COG5238 345 qeNTTLHSLDLSDNQIGDEGAIALAKylegNTTLRELNLGKNNIgkqgaeALIDALQT-NRLHTLILDGNLIGAEAQQR 422
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
643-676 |
4.91e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 38.38 E-value: 4.91e-04
10 20 30
....*....|....*....|....*....|....
gi 194440719 643 PGLQSLHLQKNQLRALPALPSLSQLELIDLSSNP 676
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNN 34
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
462-592 |
7.11e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.85 E-value: 7.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 462 AELEAGALAGLGRLIYLYLSDNQLAGLSAAA----LEGAPRLGYLYLERNRfLQVPGA-----ALRALPSLFSLHLQDNA 532
Cdd:COG5238 281 AIALAKALQGNTTLTSLDLSVNRIGDEGAIAlaegLQGNKTLHTLNLAYNG-IGAQGAialakALQENTTLHSLDLSDNQ 359
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 194440719 533 -----VDRLAPGDLGRTrALRWVYLSGNRITEVSLGALGPARELEKLH---LDRNQLREVPTGALEGL 592
Cdd:COG5238 360 igdegAIALAKYLEGNT-TLRELNLGKNNIGKQGAEALIDALQTNRLHtliLDGNLIGAEAQQRLEQL 426
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
478-675 |
1.07e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.08 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 478 LYLSDNQLA--GLS--AAALEGAPRLGYLYLERNRF--LQVP--GAALRALPSLFSLHLQDNAVDR---LAPGD-LGRTR 545
Cdd:COG5238 185 VYLGCNQIGdeGIEelAEALTQNTTVTTLWLKRNPIgdEGAEilAEALKGNKSLTTLDLSNNQIGDegvIALAEaLKNNT 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 546 ALRWVYLSGNRITEVSLGALGPARE----LEKLHLDRNQLREvpTGA------LEGLPALLELQLSGNPLRAlrDGAfQP 615
Cdd:COG5238 265 TVETLYLSGNQIGAEGAIALAKALQgnttLTSLDLSVNRIGD--EGAialaegLQGNKTLHTLNLAYNGIGA--QGA-IA 339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 194440719 616 VGRSLQHlflnssgleqicpgafsglGPGLQSLHLQKNQLRALPA------LPSLSQLELIDLSSN 675
Cdd:COG5238 340 LAKALQE-------------------NTTLHSLDLSDNQIGDEGAialakyLEGNTTLRELNLGKN 386
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
128-306 |
1.55e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 41.70 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 128 EALDGLGSLRRLELEGNAL---------EELRPGTfgalgALATLNLAHN-----ALVYLpAMAFQGLLRVRWLRLSHNA 193
Cdd:COG5238 230 EALKGNKSLTTLDLSNNQIgdegvialaEALKNNT-----TVETLYLSGNqigaeGAIAL-AKALQGNTTLTSLDLSVNR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 194 LS-----VLApEALAGLPALRRLSLHHNELQALPGPVLSQA----RGLARLELGHNPLTYAGEEdGLA-----LPGLREL 259
Cdd:COG5238 304 IGdegaiALA-EGLQGNKTLHTLNLAYNGIGAQGAIALAKAlqenTTLHSLDLSDNQIGDEGAI-ALAkylegNTTLREL 381
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 194440719 260 LLDGGALQALGPRAFA---HCPRLHTLDLRGNQLDTLPPLQGPGQLRRLR 306
Cdd:COG5238 382 NLGKNNIGKQGAEALIdalQTNRLHTLILDGNLIGAEAQQRLEQLLERIK 431
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
133-613 |
1.64e-03 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 42.17 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 133 LGSLRRLELEGNALeelrpgtFGALGALAT--LNLAHNAL--------VYLPAMAFQgllRVRWLRLSHNALSVLAPEAL 202
Cdd:COG3321 820 LPSLRRGEDELAQL-------LTALAQLWVagVPVDWSALypgrgrrrVPLPTYPFQ---REDAAAALLAAALAAALAAA 889
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 203 AGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHT 282
Cdd:COG3321 890 AALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAA 969
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 283 LDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRCPGDAA 362
Cdd:COG3321 970 AAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALA 1049
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 363 QEEEELEERAVAGPRAPPRGPPRGPGEERAVAPCPRAcvcvpesrhsscEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPR 442
Cdd:COG3321 1050 ALAAAAAAAAALALALAALLLLAALAELALAAAALAL------------AAALAAAALALALAALAAALLLLALLAALAL 1117
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 443 AAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPS 522
Cdd:COG3321 1118 AAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLL 1197
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 523 LFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSG 602
Cdd:COG3321 1198 AALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAA 1277
|
490
....*....|.
gi 194440719 603 NPLRALRDGAF 613
Cdd:COG3321 1278 AAAAAAALALA 1288
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
120-312 |
2.32e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 41.30 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 120 NHLRELPQEALDglgsLRRLELEGNALEELR---PGtfgalgaLATLNLAHNALVYLPAMAfQGLLRVRWLRLSHNALSV 196
Cdd:PRK15387 232 NNLTSLPALPPE----LRTLEVSGNQLTSLPvlpPG-------LLELSIFSNPLTHLPALP-SGLCKLWIFGNQLTSLPV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 197 LAPealaglpALRRLSLHHNELQALPgpvlSQARGLARLELGHNPLTyageedglALP----GLRELLLDGGALQALGP- 271
Cdd:PRK15387 300 LPP-------GLQELSVSDNQLASLP----ALPSELCKLWAYNNQLT--------SLPtlpsGLQELSVSDNQLASLPTl 360
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 194440719 272 -----RAFAHCPRLHTLD----------LRGNQLDTLPPLqgPGQLRRLRLQGNPL 312
Cdd:PRK15387 361 pselyKLWAYNNRLTSLPalpsglkeliVSGNRLTSLPVL--PSELKELMVSGNRL 414
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
49-290 |
2.46e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.80 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 49 RYQNLTE-----VPDAI--PELTQRLDLQGNLLKVIPAA------AFQGVPHLTHLDLRHCEVELVAEGAFRGLGRllll 115
Cdd:cd00116 31 EGNTLGEeaakaLASALrpQPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVLESLLR---- 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 116 nlaSNHLRELP--QEALDGLG-------------SLRRLELEGNALE----ELRPGTFGALGALATLNLAHNALvylpam 176
Cdd:cd00116 107 ---SSSLQELKlnNNGLGDRGlrllakglkdlppALEKLVLGRNRLEgascEALAKALRANRDLKELNLANNGI------ 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 177 afqgllrvrwlrlSHNALSVLApEALAGLPALRRLSLHHNEL-----QALPGpVLSQARGLARLELGHNPLTYAG----- 246
Cdd:cd00116 178 -------------GDAGIRALA-EGLKANCNLEVLDLNNNGLtdegaSALAE-TLASLKSLEVLNLGDNNLTDAGaaala 242
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 194440719 247 EEDGLALPGLRELLLDGGALQALGPRAFAHC----PRLHTLDLRGNQL 290
Cdd:cd00116 243 SALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKF 290
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
395-429 |
2.66e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 36.14 E-value: 2.66e-03
10 20 30
....*....|....*....|....*....|....*
gi 194440719 395 PCPRACVCVPesRHSSCEGCGLQAVPRGFPSDTQL 429
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
33-65 |
3.67e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 3.67e-03
10 20 30
....*....|....*....|....*....|...
gi 194440719 33 CPQACICdnSRRHVACRYQNLTEVPDAIPELTQ 65
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
404-677 |
3.72e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 40.92 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 404 PESRHSSCEGCGLQAVPRgFPSDTQLLDLRRN---HFPSVPRaafpGLGHLVSLHLQHCGIAELEAGalaglgrLIYLYL 480
Cdd:PRK15387 242 PELRTLEVSGNQLTSLPV-LPPGLLELSIFSNpltHLPALPS----GLCKLWIFGNQLTSLPVLPPG-------LQELSV 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 481 SDNQLAGLSAAALEgaprLGYLYLERNRFLQVPgaalrALPS-LFSLHLQDNAVDRLA--PGDLGRTralrWVYlsGNRI 557
Cdd:PRK15387 310 SDNQLASLPALPSE----LCKLWAYNNQLTSLP-----TLPSgLQELSVSDNQLASLPtlPSELYKL----WAY--NNRL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194440719 558 TevSLGALGPAreLEKLHLDRNQLREVPTgalegLPA-LLELQLSGNPLRALrdgafqPVgrslqhlflnssgleqicpg 636
Cdd:PRK15387 375 T--SLPALPSG--LKELIVSGNRLTSLPV-----LPSeLKELMVSGNRLTSL------PM-------------------- 419
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 194440719 637 afsgLGPGLQSLHLQKNQLRALP-ALPSLSQLELIDLSSNPF 677
Cdd:PRK15387 420 ----LPSGLLSLSVYRNQLTRLPeSLIHLSSETTVNLEGNPL 457
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
278-312 |
8.29e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.91 E-value: 8.29e-03
10 20 30
....*....|....*....|....*....|....*
gi 194440719 278 PRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPL 312
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNK 35
|
|
| |
