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Conserved domains on  [gi|256818804|ref|NP_659086|]
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little elongation complex subunit 1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mplasa_alph_rch super family cl37461
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 24-192 1.00e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


The actual alignment was detected with superfamily member TIGR04523:

Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    24 SLQQNLNEYVEALIALKQkiiNTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKS 103
Cdd:TIGR04523  465 SLETQLKVLSRSINKIKQ---NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   104 SLklyqdthqeyarvKEECLRTDaqkkkLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNE--K 181
Cdd:TIGR04523  542 DL-------------EDELNKDD-----FELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDliK 603

                          170
                   ....*....|.
gi 256818804   182 ELRHIGTQISS 192
Cdd:TIGR04523  604 EIEEKEKKISS 614
 
Name Accession Description Interval E-value
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 24-192 1.00e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    24 SLQQNLNEYVEALIALKQkiiNTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKS 103
Cdd:TIGR04523  465 SLETQLKVLSRSINKIKQ---NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   104 SLklyqdthqeyarvKEECLRTDaqkkkLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNE--K 181
Cdd:TIGR04523  542 DL-------------EDELNKDD-----FELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDliK 603

                          170
                   ....*....|.
gi 256818804   182 ELRHIGTQISS 192
Cdd:TIGR04523  604 EIEEKEKKISS 614
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
34-190 2.51e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   34 EALIALKQKIINTDNLLTEYQKKCDELQF-------ARRENSTLHHQVEQMLQKISP------LQKCQEELGSLKAELEE 100
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEEleeeleeLEAELEELREELEKLEKLLQLlplyqeLEALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  101 KKSSLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQT-QDFKQLRNEKKILEKEFKKTQERLDEFSKQKN 179
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLaEELEELQQRLAELEEELEEAQEELEELEEELE 230

                         170
                  ....*....|.
gi 256818804  180 EKELRHIGTQI 190
Cdd:COG4717   231 QLENELEAAAL 241
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
29-182 1.30e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   29 LNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSSLKLY 108
Cdd:PRK03918  278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256818804  109 QDTHQEYARVKEecLRTDAQKKKLEAKVKKLEEAAVKqtqdFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKE 182
Cdd:PRK03918  358 EERHELYEEAKA--KKEELERLKKRLTGLTPEKLEKE----LEELEKAKEEIEEEISKITARIGELKKEIKELK 425
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 50-210 7.03e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 7.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    50 LTEYQKKCDELQFARRENSTLHHQVEQMLQKISP-LQKCQEELGSLKAELEEKKSSLK-------------------LYQ 109
Cdd:pfam05483  249 ITEKENKMKDLTFLLEESRDKANQLEEKTKLQDEnLKELIEKKDHLTKELEDIKMSLQrsmstqkaleedlqiatktICQ 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   110 DTHQEYARVKEECLRTDAQK---KKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEK--ELR 184
Cdd:pfam05483  329 LTEEKEAQMEELNKAKAAHSfvvTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKevELE 408

                          170       180
                   ....*....|....*....|....*.
gi 256818804   185 HIGTQISSDSHGSIDKRKVKVLLKEL 210
Cdd:pfam05483  409 ELKKILAEDEKLLDEKKQFEKIAEEL 434
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 26-122 9.44e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 9.44e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804     26 QQNLNEYVEALIALKQKIINTDNLLTEYQK---KCD--ELQFARRENSTLHHQVEQMLQKISPLQkcqEELGSLKAELEE 100
Cdd:smart00787  167 LELLNSIKPKLRDRKDALEEELRQLKQLEDeleDCDptELDRAKEKLKKLLQEIMIKVKKLEELE---EELQELESKIED 243

                            90       100
                    ....*....|....*....|..
gi 256818804    101 KKSSLKLYQDTHQEYARVKEEC 122
Cdd:smart00787  244 LTNKKSELNTEIAEAEKKLEQC 265
 
Name Accession Description Interval E-value
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 24-192 1.00e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    24 SLQQNLNEYVEALIALKQkiiNTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKS 103
Cdd:TIGR04523  465 SLETQLKVLSRSINKIKQ---NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   104 SLklyqdthqeyarvKEECLRTDaqkkkLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNE--K 181
Cdd:TIGR04523  542 DL-------------EDELNKDD-----FELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDliK 603

                          170
                   ....*....|.
gi 256818804   182 ELRHIGTQISS 192
Cdd:TIGR04523  604 EIEEKEKKISS 614
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
34-190 2.51e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   34 EALIALKQKIINTDNLLTEYQKKCDELQF-------ARRENSTLHHQVEQMLQKISP------LQKCQEELGSLKAELEE 100
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEEleeeleeLEAELEELREELEKLEKLLQLlplyqeLEALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  101 KKSSLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQT-QDFKQLRNEKKILEKEFKKTQERLDEFSKQKN 179
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLaEELEELQQRLAELEEELEEAQEELEELEEELE 230

                         170
                  ....*....|.
gi 256818804  180 EKELRHIGTQI 190
Cdd:COG4717   231 QLENELEAAAL 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
23-184 1.14e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   23 ASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCD------ELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKA 96
Cdd:COG4717    91 AELQEELEELEEELEELEAELEELREELEKLEKLLQllplyqELEALEAELAELPERLEELEERLEELRELEEELEELEA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   97 ELEEKKSSL--KLYQDTHQEYARVKEecLRTDAQkkkleakvkKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEF 174
Cdd:COG4717   171 ELAELQEELeeLLEQLSLATEEELQD--LAEELE---------ELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239

                         170
                  ....*....|
gi 256818804  175 SKQKNEKELR 184
Cdd:COG4717   240 ALEERLKEAR 249
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 39-210 1.34e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    39 LKQKIINTDNLLTEYQKKCDELQfarRENSTLHHQVEQMLQKISPLQKCQEELGSLKA---ELEEKKSSLK-LYQDTHQE 114
Cdd:TIGR04523  164 LKKQKEELENELNLLEKEKLNIQ---KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESqisELKKQNNQLKdNIEKKQQE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   115 YARVKEECLRTDAQkkkleakvkkLEEAAVKQTQDFKQL--------RNEKKI--LEKEFKKTQERLDEFSKQKN----- 179
Cdd:TIGR04523  241 INEKTTEISNTQTQ----------LNQLKDEQNKIKKQLsekqkeleQNNKKIkeLEKQLNQLKSEISDLNNQKEqdwnk 310

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 256818804   180 ---------EKELRHIGTQIsSDSHGSID--KRKVKVLLKEL 210
Cdd:TIGR04523  311 elkselknqEKKLEEIQNQI-SQNNKIISqlNEQISQLKKEL 351
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 23-180 6.77e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 6.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    23 ASLQQNLNEYVEALIALKQKIintDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKK 102
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESEL---EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   103 SSLKLYQDTHQEYARVKEEclrTDAQKKKLEAKVKKLEEAAVKQtqDFKQLRNEKKIL-------EKEFKKTQERLDEFS 175
Cdd:TIGR02168  932 EGLEVRIDNLQERLSEEYS---LTLEEAEALENKIEDDEEEARR--RLKRLENKIKELgpvnlaaIEEYEELKERYDFLT 1006


                   ....*
gi 256818804   176 KQKNE 180
Cdd:TIGR02168 1007 AQKED 1011
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
23-189 8.32e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 8.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   23 ASLQQNLNEYVEALIALKQKIINT----DNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKispLQKCQEELGSLKAEL 98
Cdd:COG4372    27 AALSEQLRKALFELDKLQEELEQLreelEQAREELEQLEEELEQARSELEQLEEELEELNEQ---LQAAQAELAQAQEEL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   99 EEKKSSlklYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQK 178
Cdd:COG4372   104 ESLQEE---AEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180

                         170
                  ....*....|.
gi 256818804  179 NEKELRHIGTQ 189
Cdd:COG4372   181 AEQALDELLKE 191
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
29-182 1.30e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   29 LNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSSLKLY 108
Cdd:PRK03918  278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256818804  109 QDTHQEYARVKEecLRTDAQKKKLEAKVKKLEEAAVKqtqdFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKE 182
Cdd:PRK03918  358 EERHELYEEAKA--KKEELERLKKRLTGLTPEKLEKE----LEELEKAKEEIEEEISKITARIGELKKEIKELK 425
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 24-185 1.33e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    24 SLQQNLNEYVEALIALKQKIINT----DNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPL--QKCQEELGSLKAE 97
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLkdeqNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnQKEQDWNKELKSE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    98 LEEKKSSL-----------KLYQDTHQEYARVKEEC--LRTDAQkkkleAKVKKLEEaavKQT-------------QDFK 151
Cdd:TIGR04523  316 LKNQEKKLeeiqnqisqnnKIISQLNEQISQLKKELtnSESENS-----EKQRELEE---KQNeieklkkenqsykQEIK 387

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 256818804   152 QLRNEKKILEKEFKKT-------QERLDEFSKQKNEKELRH 185
Cdd:TIGR04523  388 NLESQINDLESKIQNQeklnqqkDEQIKKLQQEKELLEKEI 428
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 26-210 1.35e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    26 QQNLNEYVEALIALKQ-KIINTDNLLTEYQKKCDELQfarrenstlhhqveqmlQKISPLQKCQEELGS----LKAELEE 100
Cdd:TIGR04523  305 EQDWNKELKSELKNQEkKLEEIQNQISQNNKIISQLN-----------------EQISQLKKELTNSESenseKQRELEE 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   101 KKSSLKLYQDTHQEYarvKEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFK-------KTQERLDE 173
Cdd:TIGR04523  368 KQNEIEKLKKENQSY---KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIErlketiiKNNSEIKD 444

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 256818804   174 FSKQKNEKEL---------RHIGTQIS--SDSHGSIdKRKVKVLLKEL 210
Cdd:TIGR04523  445 LTNQDSVKELiiknldntrESLETQLKvlSRSINKI-KQNLEQKQKEL 491
PYST-B TIGR01597
Plasmodium yoelii subtelomeric family PYST-B; This model represents a paralogous family of ...
 26-180 2.83e-04

Plasmodium yoelii subtelomeric family PYST-B; This model represents a paralogous family of Plasmodium yoelii genes preferentially located in the subtelomeric regions of the chromosomes. There are no obvious homologs to these genes in any other organism.


Pssm-ID: 130658  Cd Length: 255  Bit Score: 44.89  E-value: 2.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    26 QQNLNEYVEALIALKqkiintdNLLTEYQKKCDELQFAR----------RENSTLH--HQVEQMLQKIspLQKCQEELGS 93
Cdd:TIGR01597   54 QFDLNEFYQSTLSLA-------NQFNDCNDDDKEIAHLRniidshikkhKERNTLPdlNNVDKKTKKL--INKLQKELEE 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    94 LKAELEEKKSSLKLYQDTHQEYARVKEEclrtdaqkkkleakvkkleEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDE 173
Cdd:TIGR01597  125 LKKELDNEMNDELTIQPIHDKIIIKKDE-------------------NNSVSEHEDFKQLENEKNSSVSEHEEFDIASSD 185


                   ....*..
gi 256818804   174 FSKQKNE 180
Cdd:TIGR01597  186 NLKIKRK 192
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 16-184 2.91e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 2.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    16 LARCQGCASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKIS-PLQKCQEELGSL 94
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEaEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    95 KAELEEKKSSLKLYQDTHQEYARVKEEClrtDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEF 174
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEA---EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          170
                   ....*....|
gi 256818804   175 SKQKNEKELR 184
Cdd:TIGR02168  830 ERRIAATERR 839
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 50-210 7.03e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 7.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    50 LTEYQKKCDELQFARRENSTLHHQVEQMLQKISP-LQKCQEELGSLKAELEEKKSSLK-------------------LYQ 109
Cdd:pfam05483  249 ITEKENKMKDLTFLLEESRDKANQLEEKTKLQDEnLKELIEKKDHLTKELEDIKMSLQrsmstqkaleedlqiatktICQ 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   110 DTHQEYARVKEECLRTDAQK---KKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEK--ELR 184
Cdd:pfam05483  329 LTEEKEAQMEELNKAKAAHSfvvTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKevELE 408

                          170       180
                   ....*....|....*....|....*.
gi 256818804   185 HIGTQISSDSHGSIDKRKVKVLLKEL 210
Cdd:pfam05483  409 ELKKILAEDEKLLDEKKQFEKIAEEL 434
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
24-211 7.22e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 44.13  E-value: 7.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   24 SLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKI--SPLQKCQE-----ELGSLKA 96
Cdd:COG1340    68 ELNEKVKELKEERDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQqtEVLSPEEEkelveKIKELEK 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   97 ELEEKKSSLKLYQDTHQEYARVKEecLRTDAQKKKLEAKVKKlEEA--AVKQTQDFKQLRNE--KKILE--KEFKKTQER 170
Cdd:COG1340   148 ELEKAKKALEKNEKLKELRAELKE--LRKEAEEIHKKIKELA-EEAqeLHEEMIELYKEADElrKEADElhKEIVEAQEK 224

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 256818804  171 LDEFSKQKNE--KELRHIGTQISS--DSHGSIDKRKVKVLLKELW 211
Cdd:COG1340   225 ADELHEEIIElqKELRELRKELKKlrKKQRALKREKEKEELEEKA 269
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
27-176 7.56e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   27 QNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSSLK 106
Cdd:PRK03918  207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK 286

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256818804  107 LYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAA---VKQTQDFKQLRNEKKILEKEFKKTQERLDEFSK 176
Cdd:PRK03918  287 ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIngiEERIKELEEKEERLEELKKKLKELEKRLEELEE 359
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
25-181 1.82e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   25 LQQNLNEYVEALIALKQKIINTDNLLTEYQKkcdELQFARRENSTLHHQVEQMLQKISPLQkcqEELGSLKAELEEKKSS 104
Cdd:COG4372    43 LQEELEQLREELEQAREELEQLEEELEQARS---ELEQLEEELEELNEQLQAAQAELAQAQ---EELESLQEEAEELQEE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  105 LklyQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFK-----KTQERLDEFSKQKN 179
Cdd:COG4372   117 L---EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQalseaEAEQALDELLKEAN 193


                  ..
gi 256818804  180 EK 181
Cdd:COG4372   194 RN 195
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 90-184 2.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    90 ELGSLKAELEEKKSSLKLYQDTHQEYARVKEEClrtDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQE 169
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQEL---EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90
                   ....*....|....*
gi 256818804   170 RLDEFSKQKNEKELR 184
Cdd:TIGR02168  310 RLANLERQLEELEAQ 324
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 63-174 2.53e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 2.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   63 ARRENSTLHHQVEQMLQKISPLQKCQE-----------ELGSLKAELEEKKSSL-----KLYQDTHQEYARVKEECLRTD 126
Cdd:PRK00409  507 AKKLIGEDKEKLNELIASLEELERELEqkaeeaeallkEAEKLKEELEEKKEKLqeeedKLLEEAEKEAQQAIKEAKKEA 586

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 256818804  127 AQKKKLEAKVKKLEEAAVK--QTQD-FKQLRNEKKILEKEFKKTQERLDEF 174
Cdd:PRK00409  587 DEIIKELRQLQKGGYASVKahELIEaRKRLNKANEKKEKKKKKQKEKQEEL 637
IFT57 pfam10498
Intra-flagellar transport protein 57; Eukaryotic cilia and flagella are specialized organelles ...
 25-105 2.76e-03

Intra-flagellar transport protein 57; Eukaryotic cilia and flagella are specialized organelles found at the periphery of cells of diverse organizms. Intra-flagellar transport (IFT) is required for the assembly and maintenance of eukaryotic cilia and flagella, and consists of the bidirectional movement of large protein particles between the base and the distal tip of the organelle. IFT particles contain multiple copies of two distinct protein complexes, A and B, which contain at least 6 and 11 protein subunits. IFT57 is part of complex B but is not, however, required for the core subunits to stay associated. This protein is known as Huntington-interacting protein-1 in humans.


Pssm-ID: 463118 [Multi-domain]  Cd Length: 360  Bit Score: 42.25  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    25 LQQNLNEYVEAlIALKQKIINT--DNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKispLQKCQEELGSLKAELEEKK 102
Cdd:pfam10498  248 LHTDISKTLEK-IESREKYINSqlEPLIQEYREAQDELSEVQEKYKQLSEGVTERTRE---LAEITEELEKVKQEMEERG 323


                   ...
gi 256818804   103 SSL 105
Cdd:pfam10498  324 SSM 326
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 34-209 2.83e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    34 EALIALKQKIintDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSslklyqDTHQ 113
Cdd:TIGR02169  357 EEYAELKEEL---EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA------DLNA 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   114 EYARVKEECLRTDAQkkkleakVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQ--KNEKELRHIGTQIS 191
Cdd:TIGR02169  428 AIAGIEAKINELEEE-------KEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKElsKLQRELAEAEAQAR 500

                          170
                   ....*....|....*...
gi 256818804   192 SDSHGSIDKRKVKVLLKE 209
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKA 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 22-191 3.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 3.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    22 CASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDEL-----------QFARRENSTLHHQVEQMLQKISPLQKCQEE 90
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaneisrleqqkQILRERLANLERQLEELEAQLEELESKLDE 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    91 LGSLKAELEEKKSSLKlyqdthQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNE-------------- 156
Cdd:TIGR02168  335 LAEELAELEEKLEELK------EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQiaslnneierlear 408

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 256818804   157 KKILEKEFKKTQERLDEFSKQKNEKELRHIGTQIS 191
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELE 443
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
40-223 3.47e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   40 KQKIINTDNLlteyqkkcDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQDTHQEYARVK 119
Cdd:COG4717    64 RKPELNLKEL--------KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  120 EeclrTDAQKKKLEAKVKKLEEaavkQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKELRHIGTQIssDSHGSID 199
Cdd:COG4717   136 A----LEAELAELPERLEELEE----RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLA--EELEELQ 205

                         170       180
                  ....*....|....*....|....
gi 256818804  200 KRkVKVLLKELWLCVNTAHRLSGE 223
Cdd:COG4717   206 QR-LAELEEELEEAQEELEELEEE 228
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 23-180 4.07e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 4.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    23 ASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARREnstLHHQVEQMLQKISPLQKCQEELGSLKAELEEKK 102
Cdd:TIGR02169  871 EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK---KRKRLSELKAKLEALEEELSEIEDPKGEDEEIP 947

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   103 SSLKLYQDTHQEYARVKEEcLRTdaqkkkleakvkkLEEAAVKQTQDFKQ-------LRNEKKILEKEFKKTQERLDEFS 175
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEE-IRA-------------LEPVNMLAIQEYEEvlkrldeLKEKRAKLEEERKAILERIEEYE 1013


                   ....*
gi 256818804   176 KQKNE 180
Cdd:TIGR02169 1014 KKKRE 1018
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
68-182 4.26e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   68 STLHHQVEQMLQKIspLQKCQEELGS--------LKAELEEKKSSLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKL 139
Cdd:COG4717    37 STLLAFIRAMLLER--LEKEADELFKpqgrkpelNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL 114

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 256818804  140 EE---------AAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKE 182
Cdd:COG4717   115 REeleklekllQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELE 166
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
23-184 4.39e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 41.43  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   23 ASLQQNLNEyVEALIALKQKIintDNLLTEYQKKcdelqfaRRENSTLHHQVEQMLQKIsplQKCQEELGSLKAELEEKK 102
Cdd:COG1340   143 KELEKELEK-AKKALEKNEKL---KELRAELKEL-------RKEAEEIHKKIKELAEEA---QELHEEMIELYKEADELR 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  103 SSLKLYqdtHQEYarvkeeclrtdaqkkkleakvKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKE 182
Cdd:COG1340   209 KEADEL---HKEI---------------------VEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEE 264


                  ..
gi 256818804  183 LR 184
Cdd:COG1340   265 LE 266
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 26-209 7.40e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 7.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    26 QQNLNEYVEALIALKQKIINTDN----LLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPL-----------QKCQEE 90
Cdd:TIGR04523  334 NKIISQLNEQISQLKKELTNSESenseKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLeskiqnqeklnQQKDEQ 413

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804    91 LGSLKAELEEKkssLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLE------------------------EAAVKQ 146
Cdd:TIGR04523  414 IKKLQQEKELL---EKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDntresletqlkvlsrsinkikqnlEQKQKE 490

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256818804   147 ----TQDFKQLRNEKKILEKEFKKTQERLDEF-SKQKN-EKELRHIGTQISS--DSHGSIDKRKVKVLLKE 209
Cdd:TIGR04523  491 lkskEKELKKLNEEKKELEEKVKDLTKKISSLkEKIEKlESEKKEKESKISDleDELNKDDFELKKENLEK 561
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 23-252 8.67e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804   23 ASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQfarRENSTLHHQVEQMLQKISPLQKcqeELGSLKAELEEKK 102
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAALEAELAELEK---EIAELRAELEAQK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  103 SSLK-----LYQDTHQEYARV---KEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEF 174
Cdd:COG4942   104 EELAellraLYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804  175 SKQKNE-KELRHIGTQISSDSHGSIDKRKVKvlLKELWLCVNTAHRLSGEGGRRIPEKPAKGSSAARASEQDEL-LPVQG 252
Cdd:COG4942   184 EEERAAlEALKAERQKLLARLEKELAELAAE--LAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLpWPVSG 261
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 26-122 9.44e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 9.44e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818804     26 QQNLNEYVEALIALKQKIINTDNLLTEYQK---KCD--ELQFARRENSTLHHQVEQMLQKISPLQkcqEELGSLKAELEE 100
Cdd:smart00787  167 LELLNSIKPKLRDRKDALEEELRQLKQLEDeleDCDptELDRAKEKLKKLLQEIMIKVKKLEELE---EELQELESKIED 243

                            90       100
                    ....*....|....*....|..
gi 256818804    101 KKSSLKLYQDTHQEYARVKEEC 122
Cdd:smart00787  244 LTNKKSELNTEIAEAEKKLEQC 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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