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Conserved domains on  [gi|33859793|ref|NP_775765|]
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dynein axonemal assembly factor 6 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PIH1_CS super family cl38976
PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists ...
 110-202 5.51e-05

PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists of a seven-stranded beta sandwich with the topology of a CS domain, a structural motif also found in Hsp90 co-chaperones such as p23/Sba1 and Sgt1.


The actual alignment was detected with superfamily member pfam18201:

Pssm-ID: 408028 [Multi-domain]  Cd Length: 100  Bit Score: 40.86  E-value: 5.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859793   110 PEYEIIFRQQVGTEDIFLGLSKKDSstGCCSELVAKIKLPN-TNPSDIQIDIQETILDL--RTPQKKLLITLPELVECTS 186
Cdd:pfam18201   4 PKYKLRYRSYVDYQDFTDERDSKRS--TVPKELVIEIYLPLlTSAAEIKLRVTERRLVLesEKAKYFLSLKLPYPVDEDR 81

                          90
                  ....*....|....*.
gi 33859793   187 AKAFYIPETETLEITM 202
Cdd:pfam18201  82 GSAKFNKKTRTLKVTL 97
 
Name Accession Description Interval E-value
PIH1_CS pfam18201
PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists ...
 110-202 5.51e-05

PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists of a seven-stranded beta sandwich with the topology of a CS domain, a structural motif also found in Hsp90 co-chaperones such as p23/Sba1 and Sgt1.


Pssm-ID: 408028 [Multi-domain]  Cd Length: 100  Bit Score: 40.86  E-value: 5.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859793   110 PEYEIIFRQQVGTEDIFLGLSKKDSstGCCSELVAKIKLPN-TNPSDIQIDIQETILDL--RTPQKKLLITLPELVECTS 186
Cdd:pfam18201   4 PKYKLRYRSYVDYQDFTDERDSKRS--TVPKELVIEIYLPLlTSAAEIKLRVTERRLVLesEKAKYFLSLKLPYPVDEDR 81

                          90
                  ....*....|....*.
gi 33859793   187 AKAFYIPETETLEITM 202
Cdd:pfam18201  82 GSAKFNKKTRTLKVTL 97
 
Name Accession Description Interval E-value
PIH1_CS pfam18201
PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists ...
 110-202 5.51e-05

PIH1 CS-like domain; This domain is found in yeast PIH1 and its homologs. This domain consists of a seven-stranded beta sandwich with the topology of a CS domain, a structural motif also found in Hsp90 co-chaperones such as p23/Sba1 and Sgt1.


Pssm-ID: 408028 [Multi-domain]  Cd Length: 100  Bit Score: 40.86  E-value: 5.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859793   110 PEYEIIFRQQVGTEDIFLGLSKKDSstGCCSELVAKIKLPN-TNPSDIQIDIQETILDL--RTPQKKLLITLPELVECTS 186
Cdd:pfam18201   4 PKYKLRYRSYVDYQDFTDERDSKRS--TVPKELVIEIYLPLlTSAAEIKLRVTERRLVLesEKAKYFLSLKLPYPVDEDR 81

                          90
                  ....*....|....*.
gi 33859793   187 AKAFYIPETETLEITM 202
Cdd:pfam18201  82 GSAKFNKKTRTLKVTL 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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